From owner-acedb@net.bio.net Mon Jan 10 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!swrinde!emory!emory!usenet
From: bcresas@bimcore.emory.edu (Scott Sammons)
Newsgroups: bionet.software.acedb
Subject: Problems executing xace
Date: 11 Jan 1994 16:32:06 GMT
Organization: Biomolecular Computing Resource, Emory University
Lines: 28
Distribution: world
Message-ID: <2guka6INNls0@emory.mathcs.emory.edu>
Reply-To: bcresas@bimcore.emory.edu
NNTP-Posting-Host: bimcore.cc.emory.edu

I'm having a problem getting acedb to run properly.  When I type acedb, I get
the following error message:

ld.so.1: xace: fatal: libXaw.so.5: can't open file: errno=2
Killed

libXaw.so.5 is found in /usr/openwin/lib which is

The strange thing is that I can get it to work if I am the owner of the 
executable xace.  Is something wrong with my setuid?  The setuid looks like:

# ls -l xace
-rwsr-xr-x   1 gcgadmin staff    1032732 Dec 23 10:06 xace

I don't think that it's my LD_LIBRARY_PATH since when I log in as gcgadmin,
my LD_LIBRARY_PATH is the same as other userids that fail to work.

Thanks,
Scott Sammons
==============================================================================
| Scott A. Sammons                                           (404) 727-2780  |
| Emory University                                      FAX: (404) 727-3659  |
| Biomolecular Computing Resource      Internet:  sammons@bimcore.emory.edu  |
| 3025 Rollins Research Center                                               |
| Atlanta, GA 30322                                                          |
==============================================================================



From owner-acedb@net.bio.net Mon Jan 10 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: "Dave Matthews" <matthews@greengenes.cit.cornell.edu>
Newsgroups: bionet.software.acedb
Subject: syntax for -A aliasing?
Date: 11 Jan 1994 20:45:38 -0000
Lines: 9
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2gv35i$p4i@mserv1.dl.ac.uk>
Original-To: acedb@net.bio.net

Is the Alias command -A in .ace files supposed to be working?  If so, what
is the syntax?  I can do Rename with 

-R Colleague : "Old Name" "New Name"

, but -A gives error message "Unrecognized Class -A".  (This is using xace
version 1-10).

- Dave Matthews

From owner-acedb@net.bio.net Wed Jan 12 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: "Dave Matthews" <matthews@greengenes.cit.cornell.edu>
Newsgroups: bionet.software.acedb
Subject: REPLIES: syntax for -A aliasing?
Date: 13 Jan 1994 21:42:20 -0000
Lines: 26
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2h4f7s$gbl@mserv1.dl.ac.uk>
Original-To: acedb@net.bio.net

> To: acedb@net.bio.net
> From: "Dave Matthews" <matthews@greengenes.cit.cornell.edu>
> Subject: syntax for -A aliasing?
> Date: 11 Jan 1994 20:45:38 -0000
> 
> Is the Alias command -A in .ace files supposed to be working?  If so, what
> is the syntax?  I can do Rename with 
> 
> -R Colleague : "Old Name" "New Name"
> 
> , but -A gives error message "Unrecognized Class -A".  (This is using xace
> version 1-10).

Jean replied that it didn't work, so he fixed it:

: if you need it badly i can send a fixed ace2/3 source code

Richard pointed out some problems with using the Alias feature, either via
..ace files or the menu:

: I don't know if it works or not.  We don't use it because it doesn't dump
: out in ace format, so is not preserved properly in updates etc.  It works
: internally, but I think is a potential source of confusion and errors, until
: we can automatically keep track for the aliased-to object of all its alias
: names.


From owner-acedb@net.bio.net Thu Jan 13 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: "" <unknown@dl.ac.uk>
Newsgroups: bionet.software.acedb
Subject: Release 1.0 of an image analysis package for fingerprint gels
Date: 14 Jan 1994 12:29:58 -0000
Lines: 27
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2h6386$n2d@mserv1.dl.ac.uk>
Original-To: rmott@gea.icnet.uk, mieg@ppsw.cam.ac.uk, ung@ash.tree.caltech.edu,
 spark@ic.ac.uk, acedb@net.bio.net


Release 1.0 of Image, an image analysis package for fingerprint gels
--------------------------------------------------------------------

We have written an integrated program for image analysis of
physical mapping fingerprint gels for use at the Sanger Centre.
This runs on Unix workstations using X11 for display.  It
incorporates the VAX film scanning software of Sulston et
al. (CABIOS 5, 101-106, 1989) and uses the ACEDB graphics
package.

It analyses scanned fingerprint gels, finding lanes, extracting
bands from lanes, and correcting for gel distortion by aligning
known standard marker lanes.  At each stage there are hand
editing tools for correcting errors.  The output format can be
read by the Contig9 fingerprint assembly routines being
integrated into ACEDB.

The package is available by anonymous ftp from rona.sanger.ac.uk
(193.60.84.39), in directory /pub/image.

Read the files README in /pub/image and TUTORIAL in the untarred
archive for further information.

Friedemann Wobus (fw@sanger.ac.uk)
Richard Durbin (rd@sanger.ac.uk)


From owner-acedb@net.bio.net Mon Jan 17 22:00:00 1994
Path: biosci!s.u-tokyo!kuis-news!wnoc-kyo-news!oskgate0.mei!chorus.mei!panasonic.com!newsserver.jvnc.net!darwin.sura.net!gatech!howland.reston.ans.net!agate!overload.lbl.gov!acedbfaq
From: acedbfaq@s27w007.pswfs.gov (ACEDB FAQ Pseudouser)
Newsgroups: bionet.software.acedb,news.answers
Subject: ACEDB Genome Database Software FAQ
Followup-To: bionet.software.acedb
Date: 17 Jan 1994 19:34:48 GMT
Organization: Dendrome, A genome database for forest trees
Lines: 640
Approved: news-answers-request@MIT.Edu
Distribution: world
Message-ID: <2hep8o$f47@overload.lbl.gov>
Reply-To: acedbfaq@s27w007.pswfs.gov
NNTP-Posting-Host: s27w007.pswfs.gov
Summary: Frequently Asked Questions about finding and getting
 started with the database system ACEDB.  ACEDB is used
 to collect information regarding the molecular biology
 of the genome.
Archive-name: acedb-faq
Last-modifed: 1/17/94
Version: 1.7
Xref: biosci bionet.software.acedb:138 news.answers:11497

----------------------------------------------------------------------
Common Questions and Answers about ACEDB.

    This document will be posted monthly to the BIOSCI newsgroup
    bionet.software.acedb and to USENET conference news.answers.
    It is intended to be used as an index to ACEDB databases and
    to information about the database software.

    The latest version of the ACEDB FAQ should be available via
    anonymous ftp at machine net.bio.net (134.172.2.69) as
    file pub/BIOSCI/ACEDB/ACEDB.FAQ or at rtfm.mit.edu
    (18.70.0.209) as pub/usenet.news.answers/acedb-faq. Answer 3
    demonstrates a sample FTP session.  If you only have
    electronic mail, the FAQ can be retrieved from
    mail-server@rtfm.mit.edu.

    There is an HyperText Markup Language (HTML) version of this
    document available on the World Wide Web:
        http://probe.nalusda.gov:8000/plant/acedbfaq.html
    [Until I get more familiar with HTML, it may not be totally
     synchronized with the plain FAQ. --bks]

    Curators of ACEDB databases should take note of Question 4 and
    keep me apprised of changes.

    Errors of commission or omission are unintentional.  If I have
    forgotten to give you credit please let me know.  Please
    send comments and corrections to: acedbfaq@s27w007.pswfs.gov
        --Bradley K. Sherman 

----------------------------------------------------------------------
The List of questions in the ACEDB FAQ.  Questions marked with
+ are new, those with ! have substantially changed answers:

Q0:  What is ACEDB?
Q1:  !What is the current version of ACEDB?
Q2:  What hardware|software do I need to run ACEDB?
Q3:  !Where can I get ACEDB?
Q4:  What ACEDB databases exist?
Q5:  What written documentation exists for ACEDB?
Q6:  Where can I find further information about ACEDB?
Q7:  How should ACEDB be cited?
Q8:  Is ACEDB object-oriented?
Q9:  What's all this about Gopher|WAIS|Anonymous ftp|WWW|URL ...
Q10: How can I get on the ACEDB announcements mailing list?
Q11: When and where is the next ACEDB Workshop?
Q411:Who contributed to this document?

----------------------------------------------------------------------
Q0:  What is ACEDB?

A0:  ACEDB is an acronym for A Caenorhabditis elegans Database.  It can
     refer to a database and data concerning the nematode C. elegans,
     or to the database software alone.  This document is concerned
     primarily with the latter meaning.  ACEDB is being adapted by many
     groups to organize molecular biology data about the genomes of
     diverse species [see Q4].

     ACEDB allows for automatic cross-referencing of items during
     loading and allows for hypertextual navigation of the links
     using a graphical user interface and mouse.  Certain special
     purpose graphical displays have been integrated into the
     software.  These reflect the needs of molecular biologists
     in constructing genetic and physical maps of genomes.

     ACEDB was written and developed by Richard Durbin (MRC LMB
     Cambridge, England) and Jean Thierry-Mieg (CNRS, Montpellier,
     France), beginning circa 1990.  It is written in the C programming
     language and uses the X11 windowing system to provide a platform
     independent graphical user interface.  The source code is publicly
     available [See Q3].  Durbin & Thierry-Mieg continue to develop
     the system, with contributions from other groups including
     Lawrence Berkeley Laboratory and the European integrated Genome
     Project.

     A description by Durbin & Thierry-Mieg:
         ACEDB does not use an underlying relational database
         schema, but a system we wrote ourselves in which data
         are stored in objects that belong in classes.  This is
         nevertheless a general database management system using
         caches, session control, and a powerful query language.
         Typical objects are clones, genes, alleles, papers,
         sequences, etc.  Each object is stored as a tree,
         following a hierarchical structure for the class (called
         the "model").  Maps are derived from data stored in tree
         objects, but precomputed and stored as tables for
         efficiency.  The system of models allows flexibility
         and efficiency of storage -missing data are not stored.
         A major advantage is that the models can be extended
         and refined without invalidating an existing database.
         Comments can be added to any node of an object.
         Current display modes are:
             TREE   for text type objects: papers, authors, genes
             etc.
             GMAP   genetic map
             PMAP   physical map (Sulston contig style)
             SEQ    DNA sequence - symbolic, features, sequence
             and translation
             GRID   hybridisation patterns for a probe to a clone
             grid
             BIBLIO bibliography attached to any object display
             modules under development:
             CMAP   whole chromosome physical map plot
             GEL    agarose gel simulation derived from sequence

----------------------------------------------------------------------
Q1:  What is the current version of ACEDB?

A1:  As of January 1994, ACEDB has undergone a bifurcation.  Those
     involved with C. elegans will want to to track the 2.x series
     under the stewardship of Richard Durbin and all other groups
     should probably track the 3.x series of Jean Thierry-Mieg.
     Thierry-Mieg writes "... 2 and 3 differ only at the level of
     displays ..."  Version 2.0 was released in December, 1993 and
     version 3.0 was released in January, 1994.
 
     To retrieve the software see Q3.

     To be kept informed of new releases see Q10.

     [This question refers to the software not the C. elegans data.]

----------------------------------------------------------------------
Q2:  What hardware/software do I need to run ACEDB?

A2:  ACEDB currently runs on the following Unix systems, under X11:
     Unix:
         Any machine running SunOS 4.x
             e.g. Sun SPARCstation 1, 1+, 2, IPC, IPX.
         SPARCstation 10 under Solaris [Probably all Solaris, then --bks]
         DEC  DECstation3100, 5100 etc.
         DEC  Alpha/OSF-1
         Silicon Graphics Iris series
         PC 386/486 with Linux (free Unix)
        There exist, or have existed, ports onto Alliant, Hewlett-
        Packard, IBM R6000, NeXT, Convex.   You may have to contact
        the developer responsible for the port to make these real.
    MSDOS/Windows/NT:
        A port to NT is rumored to be in the works.
    Macintosh:
        A port to the Macintosh may become available real soon now.

    For cost savings, a combination of a high-end Intel platform
    with Linux appears very attractive.

    Here at the Institute of Forest Genetics we run ACEDB on a 
    Sun Microsystems SPARCstation II, and users can interact
    using Macintoshes and PC-clones by using X11 implementations
    for the personal computers and a LAN.  [This section should
    be expanded to have a more thorough discussion of X11
    interactions.  --bks]

----------------------------------------------------------------------
Q3:  Where can I get ACEDB?

A3:  All the files are available in the following public access
     accounts (anonymous ftp sites) accessible via Internet:
        lirmm.lirmm.fr (193.49.104.10) in pub/acedb
        cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb
        ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb
        bioinformatics.weizmann.ac.il (132.76.55.12) in
            pub/databases/acedb.

    A typical session would be:
        ftp ncbi.nlm.nih.gov
        login: anonymous
        password: your email address
        cd repository/acedb/ace3
        binary
        ls
        get README_3
        get NOTES
        get INSTALL
        get bin.sparc.3.0.tar.Z
        quit

----------------------------------------------------------------------
Q4:  What ACEDB databases exist?

A4:  [In alphabetic order by Database name --bks]

     Database : AAnDB
     Species : Aspergillus nidulans
     PI : Leland Ellis
     Last_update : Sept. 1993

     Database : AAtDB
     Species : Arabidopsis thaliana
     Availability : 
     Curator : John Morris
     Current version: 1-5
     Contact : curator@frodo.mgh.harvard.edu
     Last_update : Sept. 1993

     Database : ACeDB
     Species : Caenorhabditis elegans
     Availability :
     Current version: 1-21
     Curator : Jean Thierry-Mieg
     Curator : Richard Durbin
     Contact : rd@mrc-lmb.cam.ac.uk
     Contact : mieg@kaa.cnrs-mop.fr
     Last_update : Sept. 1993

     Database : ChlamyDB
     Species : Chlamydomonas
     PI : Elizabeth Harris
     Contact : chlamy@acpub.duke.edu
     Availability : Still under construction
     Last_update : 30 Sept. 1993

     Database : EcoDB
     Species : E. coli
     PI : Staffan Bergh
     Contact : staffan@biochem.kth.se
     Availability : Still under construction
     Last_update : 11 Oct. 1993

     Database : FlyBase
     Species : Drosophila melanogaster
     Availability : gopher or gopher+ ftp.bio.indiana.edu
     Availability : ACeDB-style interface to SyBase server
                    due by end of 1994
     Curator : Edward Welbourne
     Contact : eddy@gen.cam.ac.uk
     Contact : flybase@morgan.harvard.edu
     PI : William Gelbart
     PI : Michael Ashburner
     PI : Thomas Kaufman
     PI : Kathy Matthews
     PI : John Merriam

     Database : Flydb
     Species : Drosophila melanogaster
     Availability : by request only, via ftp
     Curator : Suzanna E. Lewis
     Contact : SELewis@lbl.gov
     Focus : STS content mapping project summary
     PI : Gerald Rubin
     PI : Mike Palazzolo
     PI : Dan Hartl
     PI : Alan Spradling
     Last_update : Sept. 1993

     Database : GrainGenes
     Species : Wheat, barley, oats, relatives
     Availability : Gopher greengenes.cit.cornell.edu port 70
     Availability : ACEDB version by ftp, on request from the curators
     Curator : David E. Matthews
     PI : Olin D. Anderson
     Contact : matthews@greengenes.cit.cornell.edu
     Contact : oandersn@wheat.usda.gov
     Last_update : Sept. 1993

     Database : Mace
     Species : Zea mays L. ssp. mays
     Focus : Maize genome
     Comment : Mace is the front end for maizedb, a relational
               (SYBASE) database. It is updated from maizedb by
               software written by Stan Letovsky.  Maizedb is
               updated daily and will soon be accessible by
               public login.
     Curator : Ed Coe 
     Curator : Pat Byrne
     Curator : Georgia Davis
     Curator : Mary Polacco
     Off-Site Curator : Marty Sachs 
     Off-Site Curator : Christiane Fauron 
     Off-Site Curator : Carolyn Wetzel
     Off-Site Curator : Steve Rodermel 
     Off-Site Curator/Designer : Stan Letovsky 
     Off-Site Curator/Designer : Mary Berlyn 
     Systems Manager : Denis Hancock
     PI : Ed Coe
     Contact : maizedb@teosinte.agron.missouri.edu
     Last_update: 5 October 1993

     Database : MycDB
     Species : Mycobacterium
     PI : Staffan Bergh
     PI : Thierry Garnier
     Contact : staffan@pasteur.fr
     Last_update : Sept. 1993

     Database : RiceGenes
     Species : Rice (O. sative)
     Availability : under development, login at own risk
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SolGenes
     Coverage: Solanaceae - tomato, potato, pepper (eventually)
     Availability : Beta ACEDB via login or tar file
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SoyBase
     Species : Soybeans
     Curator :  Lisa Lorenzen
     PI : Randy Shoemaker
     Contact : lorenzen@mendel.agron.iastate.edu
     Last_update : Sept. 1993

     Database : TreeGenes
     Species : Forest trees, Pinus taeda
     Availability : contact curator
     Curator : Bradley K. Sherman
     PI : David B. Neale
     Contact : Dendrome@s27w007.pswfs.gov
     Contact : bks@s27w007.pswfs.gov
     Contact : dbn@s27w007.pswfs.gov
     Last_update : Sept. 1993

     Database : 21Bdb
     Species : Homo sapiens
     Availability : by request, via ftp, gopher
     Curator : Donn F. Davy
     Contact : DFDavy@lbl.gov
     Contact : aggarwal@genome.lbl.gov
     Focus : STS content mapping & sequencing of Human Chromosome 21
     PI : Jasper Rine
     PI : Michael Palazzolo
     PI : Chris Martin
     PI : Jan-Fang Cheng
     Last_update : Sept. 1993

     Database : VoxPop
     Species : Populus spp.
     Availability : contact curator
     Curator : Carl G. Riches
     PI : Reinhard F. Stettler
     Contact : cgr@poplar1.cfr.washington.edu
     Contact : STETTLER@coyote.cfr.washington.edu
     Last_update : Sept. 1993

     Database : ?
     Species : Bovine
     PI : Leland Ellis
     Last_update : Sept. 1993

     Database : ?
     Species : Sorghum
     PI : Leland Ellis
     Last_update : Sept. 1993

     Database : ?
     PI : Scott Chasalow
     Species : Potato
     Contact : Scottish Crop Institute, Dundee
     Last_update : Sept. 1993

     Database : ?
     PI : George Murphy
     PI : David Flanders
     Species : Arabidopsis thaliana
     Contact : John Innes Center, Norwich, England
     Last_update : Sept. 1993

     Database : ?
     Species : Homo sapiens
     Focus : Physical mapping of human chromosomes 22 and X
     Curator : Ian Dunham
     Contact : idunham@crc.ac.uk id1@sanger.ac.uk
     PI : Ian Dunham
     PI : David Bentley
     Last_update : 28 Sep 1993

     [Curators:  Please submit an entire paragraph in
      this format for inclusion or update. --bks]


----------------------------------------------------------------------
Q5:  What written documentation exists for ACEDB?

A5:  The primary documents are included in the Software
     distribution in the wdoc subdirectory:
         acedb -- A C. elegans Database: I. Users' Guide.
         acedb -- A C. elegans Database: II. Installation Guide.
         acedb -- A C. elegans Database: III. Configuration Guide.
         Syntactic Definitions for the ACEDB Data Base Manager
             --Jean Thierry-Mieg and Richard Durbin (1991-)
     You will find other interesting documents in the wdoc subdirectory.

     By anonymous ftp from ncbi.nlm.nih.gov (130.14.20.1)
     in repository/acedb:
        doc.1_9.tar.Z

     Cherry, J.M., Cartinhour, S.W., and Goodman, H.M. (1992) AAtDB,
     An Arabidopsis thaliana Database. Plant Molecular Biology Reporter
     10 (4): 308-309,409-410

     Tutorial manual for AAtDB:
     Cartinhour, S., Cherry, J.M., and Goodman, H.M. (1992) An
     Introduction to ACeDB: For AAtDB, An Arabidopsis thaliana
     Database. Massachusetts General Hospital. (Available on
     request in printed form from the AAtDB curator).

     A description of ACEDB:
     Cherry, J.M. and Cartinhour, S.W. (1993) ACEDB, A tool for
     biological information. in Automated DNA Sequencing and
     Analysis, edited by M.  Adams, C. Fields, and C. Venter.
     Academic Press (in press).  [text is available through
     ftp or gopher from weeds.mgh.harvard.edu]

     Another description of ACEDB for physical mapping projects:
     Dunham, I., Durbin, R., Mieg, J-T & Bentley, D.R. (1993)
     Physical mapping projects and ACEDB, in Guide to Human
     Genome Computing. Ed.  Bishop, M.J.  (Academic Press)
     (review, in press).  [text is available through ftp or
     gopher from weeds.mgh.harvard.edu]

----------------------------------------------------------------------
Q6:  Where can I find further information about ACEDB?

A6:  There is a Usenet/Biosci conference titled bionet.software.acedb.
     If you do not have access to the Biosci conferences via a
     newsreader (e.g. rn, trn) you can participate in the conference
     by electronic mail.  To subscribe to the e-mail version of the
     conference send email to biosci-server@net.bio.net (UK, European
     readers use biosci@uk.ac.daresbury or biosci.daresbury.ac.uk) with
     no subject line and only the message
           subscribe ACEDB-SOFT
     in the body.  To unsubscribe send the message
           unsubscribe ACEDB-SOFT
     to the same address.
     This is an automated service.  Your e-mail address will be taken
     from the header of the message that you send.  If you then send
     mail to acedb@net.bio.net the mail will be distributed to all
     subscribers and to the electronic conference.

     Mike Cherry has set up an ACEDB Developer's archive.  For
     anonymous ftp use the hostname weeds.mgh.harvard.edu and look in
     the acedb_dev directory. If you wish to contribute you can put
     files in the incoming directory.  Send a message to Mike
     (cherry@genome.stanford.edu) that you have put something in that
     directory then Mike will move it out for general access.
     For gopher you can connect to weeds.mgh.harvard.edu
     (132.183.190.21) and ...
        -->  N.  FTP Archives for Molecular Biology/
     then
        -->  M.  ACEDB Developer's archive/
     [N and M are integers which are subject to change.]

     The bionet.software. acedb.conference is archived and can be
     searched using WAIS.  Here is a Gopher-style link to the WAIS
     archive. (This is also courtesy of Mike Cherry.):
          #
          Type=7
          Name=ACEDB BioSci Electronic Conference
          Path=7/.index/acedb-biosci
          Host=genome-gopher.stanford.edu
          Port=70

     The AAtDB, Soybase, GrainGenes, Mace, and TreeGenes (see Q4)
     databases regularly submit data to the Plant Genome Database
     at the National Agricultural Library (NAL).  Nal makes this
     data available via the WWW using an http server with URL:
         http://probe.nalusda.gov:8000/index.html
     You will also find a selection of models.wrm files (schemata)
     for the various databases here.  You will want to get a
     "mosaic client" to examine this.

     Other URL's that readers with mosaic clients might want to
     examine are:
        http://moulon.inra.fr/acedb/acedb.html for C. elegans data
        http://moulon.inra.fr/acedb/mycdb.html for Mycobacterium data
        http://mouIon.inra.fr:8001/acedb/igd.html for an integrated
            genome database.
     For information on how these were created see
        http://moulon.inra.fr/acedb_conf_eng.html"
        http://moulon.inra.fr/acedb_conf.html (en francais)

     The Genome Computing Group, Lawrence Berkeley Laboratory
     has an anonymous ftp service at machine genome.lbl.gov
     (131.243.224.80) which contains:
          flydb - LBL's Drosophila Acedb-style database
          21bdb - LBL's Human Chromosome 21 Acedb-style database
          querdb - LBL's query-language extensions to Acedb 
          metadata - LBL's compendium of Acedb database schema variants
          macace-aatdb-demo.hqx  -  pre-release Acedb MacIntosh version
          There is also a repository of contributed software for
          data conversions and the like.

     Computer staff for the UC Berkeley Drosophila physical mapping
     project the LBL Human Chromosome 21 project, and the LBL plant
     genome projects meet regularly to coordinate their ACEDB
     extension and development efforts, along with Frank Eeckman,
     who is working on the Macintosh version of ACEDB (for further
     information, contact jlmccarthy@lbl.gov). They also keep in
     close touch (via email, personal visits, etc.) with their
     counterparts in Cambridge (Richard Durbin et al), Montpellier 
     Jean Thierry-Mieg et al), and the Interated Genome Database
     project in Heidelburg (Otto Ritter, Detlef Wolf et al).

----------------------------------------------------------------------
Q7:  How should ACEDB be cited?

A7:  From the distribution:

        We realize that we have not yet published any "real" paper on
        ACEDB.  We consider however that anonymous ftp servers are a
        form of publication. We would appreciate if users of ACEDB
        could quote:
            Richard Durbin and Jean Thierry Mieg (1991-). A C. elegans
            Database.  Documentation, code and data available from
            anonymous FTP servers at lirmm.lirmm.fr,
            cele.mrc-lmb.cam.ac.uk and  ncbi.nlm.nih.gov.

        Papers involved in database development could quote more
        precisely:
           I.   Users' Guide. Included as part of the ACEDB distribution
         kit,
           II.  Installation Guide. Included as part of the ACEDB
         distribution
           III. Configuration Guide. Included as part of the ACEDB
         distribution

        and the preprintkit, available by Anonymous FTP from ...
           Jean Thierry-Mieg and Richard Durbin (1992). Syntactic
           Definitions for the ACEDB Data Base Manager. Included as
           part of the ACEDB distribution.

             --Jean and Richard.

----------------------------------------------------------------------
Q8: Is ACEDB object-oriented?

A8: From the ACEDB User's Guide.

    A major current vogue in computer languages and database design
    is for ``object-oriented'' systems.  It's also a source of lots
    of argument.  We are just trying to build a good system, and
    don't want to get caught in the crossfire, but we do talk about
    organising our data into objects and classes.  We have undoubtedly
    been influenced by many of the ideas going around, but it isn't
    likely our system would be regarded as kosher by the object-
    oriented community.  In particular there is no class hierarchy, nor
    inheritance, and it is written in a modular but non-ideological way
    in straight C. However display and disk storage methods are class
    dependent.

    In some ways the class hierarchy is replaced by our system of
    models and trees, which seems to be rather unusual.  We think it
    is very natural for the representation of biological information,
    where for some members of a class a lot might be known about some
    aspect, but for most only a little is known.

    The advantages of our sytem over a relational database, such as
    Oracle or Sybase, is our ability to refine our descriptions without
    rebuilding the database and the possibility of organising the
    storage of data on disk according to their class, i.e. we store in
    a very different way the tree-objects and the long stretches of
    DNA sequence.

----------------------------------------------------------------------
Q9:  What's all this about Gopher/WAIS/Anonymous ftp/WWW ...

A9:  These terms all refer to Internet protocols.
     An excellent introduction to the Internet is:
       _The Whole Internet User's Guide & Catalog_,
       by Ed Krol, O'Reilly & Associates, 1992.
     Or ask your system administrator to provide you with
     a gopher client or mosaic client and begin navigating
     on your own. 

----------------------------------------------------------------------
Q10: How can I get on the ACEDB announcements mailing list?

A10: To get on or off the mailing list send mail to
     rd@mrc-lmb.cam.ac.uk or mieg@kaa.cnrs-mop.fr.
     New releases of the software are announced to
     this list.

----------------------------------------------------------------------
Q11: When and where is the Next ACEDB Workshop?

Q11: From Jean Thierry-Mieg:
         I am proposing to organize the 1994 acedb workshop 
         Monday, June 6, to Saturday, June 18, in Cargese,
         Corsica.  This place is equipped and used for summer
         school from may to october every year, this is the
         only slot yet available.

         The cost is around 3000F per person including lunch
         & lodging. Dinner is taken at the local village
         restaurant, or you can cook for yourself. It is
         possible to camp on site for free.  The place is
         beautiful, nested on a private beach, with many
         trees around. And there is plenty of work space.
         I can find some funding to cover part of the
         local costs but certainly not  pay for travels.

         The return ticket to Paris is around 1500 FF so
         3000 + 1500 = 4500 FF around 900 US $.

         This can work if at least 40 people would come
         ideal is between 50 to 80.  This may be too large
         for us.

         Could you please let me know ASAP if you are
         interested. I do not need a full commitment, but I
         have to evaluate the number of participants roughly.

         I hope 2 weeks would: 
              a) let us enjoy a very pleasant place
              b) give us time for actual programming
                 to take place on many problems
         There would be, I hope, plenty of cpu around.
             --Jean Thierry-Mieg, mieg@kaa.cnrs-mop.fr

----------------------------------------------------------------------
Q411:Who contributed to this document?
     [Note to international readers: 411 is the phone number for
     information in the USA. --bks]

A411: Major contributions in getting this FAQ off the ground
      were made by John McCarthy and Mike Cherry.  Other
      contributors include:
        Lisa Lorenzen
        David Matthews
        Edie Paul
        Donn Davy
        Eric De Mund
        Sam Cartinhour

      To add or modify information in this document, please
      send mail to: acedbfaq@s27w007.pswfs.gov

      Bradley K. Sherman
      Dendrome Project                
      Institute of Forest Genetics    
      P.O. Box 245, Berkeley, CA, 94701
      Phone: 510-559-6437 Fax: 510-559-6440  

      The Dendrome Project and TreeGenes are funded by the
      USDA-ARS Plant Genome Database Project.

---------------------End of file acedb-faq----------------------------

From owner-acedb@net.bio.net Wed Jan 19 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: mieg@kaa.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: Acedb 94 worshop
Date: 20 Jan 1994 15:18:35 -0000
Lines: 95
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2hm7cb$hkq@mserv1.dl.ac.uk>
Original-To: acedb_distrib@lirmm.lirmm.fr


acedb '94

*******************************************************************
DATES:

The acedb '94 workshop will be held july 2 to 16, in Saint Matthieu
de Treviers, a small village, 20 km north of Montpellier, at the
foot of the Pic Saint Loup.

HOUSING:

We have booked a place meant for family vacations which includes
ample space, a nice conference room and ten studios meant for 5
people (bathroom, shower, kitchenette, terrace, all nice and clean)
that we plan to share among 3 to 4 participants.  Meals will be
taken at a local restaurant.

The place is ideal for work and informal discussions and will be
well equiped with computers. The situation is nice for hiking and
allows volley-ball, ping-pong, tennis and petanque.

We can provide lists of possible hotels for those who would prefer
more privacy or find ways of accomodating families if you let us
know very soon (school ends early july in France).

Cost for 2 weeks is 1000 FF (about 200 US dollars) for housing on
site plus 2500 FF for full meals. We may get enough funding to
reduce this cost, but cannot pay for travel.

PROGRAM:

Formal presentations and general discussions will take place in the
mornings and the evenings, alternating network aspects, data handling,
displays and genome data analaysis.

The afternoons will be dedicated to data manipulation, programming
and writing documentation. The idea is to actually implement during
the meeting many of the ideas that will come up, to fuse and
coallesce the now numerous acedb-based applications into a working
modular package, and to import and consolidate large sets of
additional data.

Towards this goal, we will broadcast the following announcement 

*******************************************************************
ACEDB'94 Genome Database Workshop.

Montpellier, July 2-16, 1994

This meeting will cover the use and development of the 
ACEDB database manager central to several major genome projects,
including C.elegans, A.thaliana, human, and a number of
other plant and animal species. 

We wish to encourage people with large sets of data on other
organisms to attend this workshop. They will be helped to build,
during the meeting, a friendly graphic presentation of their own
data, in return for discussing their own experience.

*******************************************************************

FORMAT:

This meeting will be much longer than the 2 previous acedb workshops
(Cambridge 92 and Boston 93), in the hope of initiating new
collaborations and allowing concrete results. This format is usual in
physics summer schools and often very productive.

The workshop may be coupled to a 2 days presentation of acedb, open
to the general audience, and yet to be organised.

We anticipate at least the participation of people from: Berkeley,
Boston, Cambridge, Heidelberg and Montpellier, including Richard
Durbin (LMB and Sanger Centre, Cambridge), John McCarthy (LBL,
Berkeley), Otto Ritter (DKFZ, Heidelberg), Danielle and Jean
Thierry-Mieg (CNRS, Montpellier).

Please confirm your participation and forward this announcement to
your colleagues.


Danielle and Jean Thierry-Mieg 
CNRS-CRBM
BP 5051,
34033  Montpellier, France.

email mieg@kaa.cnrs-mop.fr
 (if this address fails, fall back on mieg@ncbi.nlm.nih.gov)

Tel: (33) 67 61 33 24
Fax: (33) 67 52 15 59

*******************************************************************
*******************************************************************

From owner-acedb@net.bio.net Mon Jan 24 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: "Dave Matthews" <matthews@greengenes.cit.cornell.edu>
Newsgroups: bionet.software.acedb
Subject: new Multimap feature requested
Date: 25 Jan 1994 18:53:08 -0000
Lines: 51
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i3pqk$p4p@mserv1.dl.ac.uk>
Original-To: mieg@kaa.cnrs-mop.fr

Hello Jean, greetings from Plant Genome II!  We have a request for a 
modification of the Multimap function for you, based on discussions with
the various groups here (all of whom are showing immense enthusiasm for 
ACEDB, by the way.)

Much of the scientific excitement in plant genomic mapping over the last year
has been about the surprisingly high degree of synteny exhibited by
relatively distantly related species, and now people want to put together
inter-species databases in ACEDB.  A problem that arises in doing this with
regard to the multimap is that frequently the 'same' (homoeologous) gene or
locus is called by different names in different species.  The multimap
currently only connects common loci by keying on the fact that they are
literally the same locus, i.e. they have the same name.

John McCarthy and I are thinking that the ideal solution would be if some
other tag within the ?Locus object could be used to determine which loci are
tied together in the Multimap.  Perhaps this tag could be chosen using an
option in options.wrm, analogous to the -Title option.  E.g.

     -Title  Tag : If present in some object of that class, the text following
                   will be used preferentially when referring to that object.

     -Multimap Tag : If present, the text following will be used as the key
                     for Multimap comparisons.

Then if we set the option '-Multimap Homoeologue_name' for example, the
following loci would be tied together when displayed on the multimap:

Locus : "cab 22L"
Homoeologue_name "Lhcb1"
gMap Petunia-6 121

Locus : "Cab-1C"
Homoeologue_name "Lhcb1"
gMap Pepper-2 143

Locus : "Lhcb1"
Homoeologue_name "Lhcb1"
gMap Tomato-2 156


Further it would be nice if the names shown on the multimap could be the 
actual locus names rather than the homoeologue names.  I.e. to allow
the user to select which map's nomenclature to display, or to show all 
nomenclatures beside their respective maps.

What do you think?

best regards,
- Dave Matthews, John McCarthy, Lisa Lorenzen, Sam Cartinhour


From owner-acedb@net.bio.net Mon Jan 24 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: multimap idea
Date: 25 Jan 1994 20:31:08 -0000
Lines: 4
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i3vic$dm@mserv1.dl.ac.uk>
Original-To: mieg@ppsw.cam.ac.uk


I like the idea from Matthews et al.  I also wanted to say I like the 21 database
with its multimaps very much.


From owner-acedb@net.bio.net Tue Jan 25 22:00:00 1994
Path: biosci!daresbury!bioftp.unibas.ch!citi2.fr!jussieu.fr!univ-lyon1.fr!swidir.switch.ch!scsing.switch.ch!xlink.net!howland.reston.ans.net!vixen.cso.uiuc.edu!sdd.hp.com!think.com!mbcrr!shih
From: shih@mbcrr.dfci.harvard.edu (Deborah Shih)
Newsgroups: bionet.software.acedb
Subject: ignore test
Date: 26 Jan 1994 07:36:10 GMT
Organization: Dana-Farber Cancer Institute
Lines: 7
Distribution: bionet
Message-ID: <2i56haINN1mp@early-bird.think.com>
NNTP-Posting-Host: mbcrr.harvard.edu



Sorry, just a test posted 02:30 EST Jan 26, 1994





From owner-acedb@net.bio.net Tue Jan 25 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: kirbym@har-rbu.mrc.ac.uk
Newsgroups: bionet.software.acedb
Subject: homologous genes
Date: 26 Jan 1994 15:42:51 -0000
Lines: 59
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i631r$ipm@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk


In a recent message posted to this bulletin board by Mathews et al, they
say:

> Much of the scientific excitement in plant genomic mapping over the last year
> has been about the surprisingly high degree of synteny exhibited by
> relatively distantly related species, and now people want to put together
> inter-species databases in ACEDB. A problem that arises in doing this with
> regard to the multimap is that frequently the 'same' (homoeologous) gene or
> locus is called by different names in different species.  The multimap
> currently only connects common loci by keying on the fact that they are
> literally the same locus, i.e. they have the same name.

and suggest that a tag within the ?Locus object be used to determine
which loci are tied together in the Multimap.


It's a good idea. However, we have other dificulties with regard to homologous
data. There are some species which have homologous genes but the symbols
are exactly the same. For example, the human, cow and sheep nomenclature.
As you can imagine, trying to store information with the same key causes
quite a few problems. To get around this, Jo Dicks and myself decided to
use a species prefix for all homologous data and keep the actual symbol
as a Text tag.
Eg Locus : "HsABL"
   Symbol : "ABL"

   Locus : "BvABL"
   Symbol : "ABL"

In fact, if this is done, all data items within the database need to have a
species prefix. But when it comes to displaying the data (whether on the maps
or in the keySet) we only want the symbol for that individual species, not
the symbol with the species prefix.

I tried to modify the genetic map code to do this but there are problems.
Could someone help me fix my code or if enough people want this facility,
could Jean and the acedb team offically implement this please.

The data structure for handling data objects to be displayed on the genetic
map is the SEG. It usually consists of the object's key, a few flags and the
object's position. Instead of using the key to display the object's name
(ie gene symbol) I have tried using a character pointer from within the SEG
structure. In the gMapConvert routine, this is set to point to the text
defined by the Symbol Tag definition in the ?Locus object. (ie is a Text tag,
not ?Text tag.) If this is done and later on you try and retrieve the Symbol
text, the data is corrupted and appears scrambled.

This is a pity because the only alternative which I have found that works
is: for each data object on the genetic map, retrieve its data (ie create
an OBJ for it) and then find the relevant data within the object for display.
It slows the map display down considerably and I am sure there is a better
way.

How is one expected to get help with acedb problems? Do you use this
bulletin board, or do you email Jean directly?

Michelle Kirby     (email kirbym@uk.ac.mrc.har-rbu)
Jo Dicks           (email jld@uk.ac.ox.bioch)

From owner-acedb@net.bio.net Thu Jan 27 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: mieg@kaa.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: multimap idea
Date: 27 Jan 1994 22:22:43 -0000
Lines: 13
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i9erj$99c@mserv1.dl.ac.uk>
Original-To: acedb@net.bio.net


I like the idea of Matthews and Kirby
i can implement that as suggested by Mathhews, it will also solve Kirby's problem 
and I think Danielle's requirement of easier access to homologies.

The reason the Text does not work is that a Text is only on disk and its char*
is only transient

You can only store in seg a KEY then display name(seg->key_of_homology)

The notion of -Multipmap like -Title in options is excellent i think

more on that in a few days, i ll try to implement that very soon.

From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: multimap idea
Date: 25 Jan 1994 20:31:08 -0000
Lines: 4
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i3vic$dm@mserv1.dl.ac.uk>
Original-To: mieg@ppsw.cam.ac.uk


I like the idea from Matthews et al.  I also wanted to say I like the 21 database
with its multimaps very much.


From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: "Dave Matthews" <matthews@greengenes.cit.cornell.edu>
Newsgroups: bionet.software.acedb
Subject: new Multimap feature requested
Date: 25 Jan 1994 18:53:08 -0000
Lines: 51
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i3pqk$p4p@mserv1.dl.ac.uk>
Original-To: mieg@kaa.cnrs-mop.fr

Hello Jean, greetings from Plant Genome II!  We have a request for a 
modification of the Multimap function for you, based on discussions with
the various groups here (all of whom are showing immense enthusiasm for 
ACEDB, by the way.)

Much of the scientific excitement in plant genomic mapping over the last year
has been about the surprisingly high degree of synteny exhibited by
relatively distantly related species, and now people want to put together
inter-species databases in ACEDB.  A problem that arises in doing this with
regard to the multimap is that frequently the 'same' (homoeologous) gene or
locus is called by different names in different species.  The multimap
currently only connects common loci by keying on the fact that they are
literally the same locus, i.e. they have the same name.

John McCarthy and I are thinking that the ideal solution would be if some
other tag within the ?Locus object could be used to determine which loci are
tied together in the Multimap.  Perhaps this tag could be chosen using an
option in options.wrm, analogous to the -Title option.  E.g.

     -Title  Tag : If present in some object of that class, the text following
                   will be used preferentially when referring to that object.

     -Multimap Tag : If present, the text following will be used as the key
                     for Multimap comparisons.

Then if we set the option '-Multimap Homoeologue_name' for example, the
following loci would be tied together when displayed on the multimap:

Locus : "cab 22L"
Homoeologue_name "Lhcb1"
gMap Petunia-6 121

Locus : "Cab-1C"
Homoeologue_name "Lhcb1"
gMap Pepper-2 143

Locus : "Lhcb1"
Homoeologue_name "Lhcb1"
gMap Tomato-2 156


Further it would be nice if the names shown on the multimap could be the 
actual locus names rather than the homoeologue names.  I.e. to allow
the user to select which map's nomenclature to display, or to show all 
nomenclatures beside their respective maps.

What do you think?

best regards,
- Dave Matthews, John McCarthy, Lisa Lorenzen, Sam Cartinhour


From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: kirbym@har-rbu.mrc.ac.uk
Newsgroups: bionet.software.acedb
Subject: homologous genes
Date: 26 Jan 1994 15:42:51 -0000
Lines: 59
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i631r$ipm@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk


In a recent message posted to this bulletin board by Mathews et al, they
say:

> Much of the scientific excitement in plant genomic mapping over the last year
> has been about the surprisingly high degree of synteny exhibited by
> relatively distantly related species, and now people want to put together
> inter-species databases in ACEDB. A problem that arises in doing this with
> regard to the multimap is that frequently the 'same' (homoeologous) gene or
> locus is called by different names in different species.  The multimap
> currently only connects common loci by keying on the fact that they are
> literally the same locus, i.e. they have the same name.

and suggest that a tag within the ?Locus object be used to determine
which loci are tied together in the Multimap.


It's a good idea. However, we have other dificulties with regard to homologous
data. There are some species which have homologous genes but the symbols
are exactly the same. For example, the human, cow and sheep nomenclature.
As you can imagine, trying to store information with the same key causes
quite a few problems. To get around this, Jo Dicks and myself decided to
use a species prefix for all homologous data and keep the actual symbol
as a Text tag.
Eg Locus : "HsABL"
   Symbol : "ABL"

   Locus : "BvABL"
   Symbol : "ABL"

In fact, if this is done, all data items within the database need to have a
species prefix. But when it comes to displaying the data (whether on the maps
or in the keySet) we only want the symbol for that individual species, not
the symbol with the species prefix.

I tried to modify the genetic map code to do this but there are problems.
Could someone help me fix my code or if enough people want this facility,
could Jean and the acedb team offically implement this please.

The data structure for handling data objects to be displayed on the genetic
map is the SEG. It usually consists of the object's key, a few flags and the
object's position. Instead of using the key to display the object's name
(ie gene symbol) I have tried using a character pointer from within the SEG
structure. In the gMapConvert routine, this is set to point to the text
defined by the Symbol Tag definition in the ?Locus object. (ie is a Text tag,
not ?Text tag.) If this is done and later on you try and retrieve the Symbol
text, the data is corrupted and appears scrambled.

This is a pity because the only alternative which I have found that works
is: for each data object on the genetic map, retrieve its data (ie create
an OBJ for it) and then find the relevant data within the object for display.
It slows the map display down considerably and I am sure there is a better
way.

How is one expected to get help with acedb problems? Do you use this
bulletin board, or do you email Jean directly?

Michelle Kirby     (email kirbym@uk.ac.mrc.har-rbu)
Jo Dicks           (email jld@uk.ac.ox.bioch)

From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!think.com!mbcrr!shih
From: shih@mbcrr.dfci.harvard.edu (Deborah Shih)
Newsgroups: bionet.software.acedb
Subject: ignore test
Date: 26 Jan 1994 07:36:10 GMT
Organization: Dana-Farber Cancer Institute
Lines: 7
Distribution: bionet
Message-ID: <2i56haINN1mp@early-bird.think.com>
NNTP-Posting-Host: mbcrr.harvard.edu



Sorry, just a test posted 02:30 EST Jan 26, 1994





From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!rutgers!usc!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: kirbym@har-rbu.mrc.ac.uk
Newsgroups: bionet.software.acedb
Subject: homologous genes
Message-ID: <2i631r$ipm@mserv1.dl.ac.uk>
Date: 26 Jan 94 15:42:51 GMT
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Lines: 59
Original-To: acedb@dl.ac.uk


In a recent message posted to this bulletin board by Mathews et al, they
say:

> Much of the scientific excitement in plant genomic mapping over the last year
> has been about the surprisingly high degree of synteny exhibited by
> relatively distantly related species, and now people want to put together
> inter-species databases in ACEDB. A problem that arises in doing this with
> regard to the multimap is that frequently the 'same' (homoeologous) gene or
> locus is called by different names in different species.  The multimap
> currently only connects common loci by keying on the fact that they are
> literally the same locus, i.e. they have the same name.

and suggest that a tag within the ?Locus object be used to determine
which loci are tied together in the Multimap.


It's a good idea. However, we have other dificulties with regard to homologous
data. There are some species which have homologous genes but the symbols
are exactly the same. For example, the human, cow and sheep nomenclature.
As you can imagine, trying to store information with the same key causes
quite a few problems. To get around this, Jo Dicks and myself decided to
use a species prefix for all homologous data and keep the actual symbol
as a Text tag.
Eg Locus : "HsABL"
   Symbol : "ABL"

   Locus : "BvABL"
   Symbol : "ABL"

In fact, if this is done, all data items within the database need to have a
species prefix. But when it comes to displaying the data (whether on the maps
or in the keySet) we only want the symbol for that individual species, not
the symbol with the species prefix.

I tried to modify the genetic map code to do this but there are problems.
Could someone help me fix my code or if enough people want this facility,
could Jean and the acedb team offically implement this please.

The data structure for handling data objects to be displayed on the genetic
map is the SEG. It usually consists of the object's key, a few flags and the
object's position. Instead of using the key to display the object's name
(ie gene symbol) I have tried using a character pointer from within the SEG
structure. In the gMapConvert routine, this is set to point to the text
defined by the Symbol Tag definition in the ?Locus object. (ie is a Text tag,
not ?Text tag.) If this is done and later on you try and retrieve the Symbol
text, the data is corrupted and appears scrambled.

This is a pity because the only alternative which I have found that works
is: for each data object on the genetic map, retrieve its data (ie create
an OBJ for it) and then find the relevant data within the object for display.
It slows the map display down considerably and I am sure there is a better
way.

How is one expected to get help with acedb problems? Do you use this
bulletin board, or do you email Jean directly?

Michelle Kirby     (email kirbym@uk.ac.mrc.har-rbu)
Jo Dicks           (email jld@uk.ac.ox.bioch)

From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!rutgers!sgigate.sgi.com!sgiblab!sdd.hp.com!think.com!mbcrr!shih
From: shih@mbcrr.dfci.harvard.edu (Deborah Shih)
Newsgroups: bionet.software.acedb
Subject: ignore test
Message-ID: <2i56haINN1mp@early-bird.think.com>
Date: 26 Jan 94 07:36:10 GMT
Distribution: bionet
Organization: Dana-Farber Cancer Institute
Lines: 3
NNTP-Posting-Host: mbcrr.harvard.edu



Sorry, just a test posted 02:30 EST Jan 26, 1994

From owner-acedb@net.bio.net Fri Jan 28 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: mieg@kaa.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: multimap idea
Date: 27 Jan 1994 22:22:43 -0000
Lines: 13
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2i9erj$99c@mserv1.dl.ac.uk>
Original-To: acedb@net.bio.net


I like the idea of Matthews and Kirby
i can implement that as suggested by Mathhews, it will also solve Kirby's problem 
and I think Danielle's requirement of easier access to homologies.

The reason the Text does not work is that a Text is only on disk and its char*
is only transient

You can only store in seg a KEY then display name(seg->key_of_homology)

The notion of -Multipmap like -Title in options is excellent i think

more on that in a few days, i ll try to implement that very soon.

From owner-acedb@net.bio.net Sat Jan 29 22:00:00 1994
Path: biosci!rutgers!usc!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: mieg@kaa.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: multimap idea
Message-ID: <2i9erj$99c@mserv1.dl.ac.uk>
Date: 27 Jan 94 22:22:43 GMT
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Lines: 13
Original-To: acedb@net.bio.net


I like the idea of Matthews and Kirby
i can implement that as suggested by Mathhews, it will also solve Kirby's problem 
and I think Danielle's requirement of easier access to homologies.

The reason the Text does not work is that a Text is only on disk and its char*
is only transient

You can only store in seg a KEY then display name(seg->key_of_homology)

The notion of -Multipmap like -Title in options is excellent i think

more on that in a few days, i ll try to implement that very soon.

From owner-acedb@net.bio.net Mon Jan 31 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.software.acedb
Subject: IMPORTANT BIOSCI INFORMATION
Date: 1 Feb 1994 10:02:39 -0000
Lines: 244
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2il9bv$h7t@mserv1.dl.ac.uk>
Original-To: acedb@net.bio.net


Three important items follow: BIOSCI archive searching by e-mail, the
BIOSCI FAQ, and the BIOSCI User Address Directory form.  If you have
not yet listed yourself in our e-mail address directory, please take a
few minutes to complete and return the form below.  If your address
information has changed since you listed yourself, please send us an
updated form.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net



	  **** SEARCHING BIOSCI ARCHIVES WITH WAISMAIL ****

E-mail users can search the BIOSCI archives by using our waismail
e-mail server.  For instructions send the message

help

to waismail@net.bio.net.  Leave the Subject: line blank.  Other
methods of searching the archives via WAIS and gopher are described in
the BIOSCI FAQ.


       **** BIOSCI FREQUENTLY ASKED QUESTIONS (FAQ) SHEET ****

New users of BIOSCI/bionet may want to read the "Frequently Asked
Questions" or "FAQ" sheet for BIOSCI.  The FAQ provides details on how
to participate in these forums and is available for anonymous FTP from
net.bio.net [134.172.2.69] in pub/BIOSCI/biosci.FAQ or for retrieval
by gopher to net.bio.net, port 70.  It may also be requested by
sending e-mail to biosci@net.bio.net (use plain English for your
request).  The FAQ is also posted on the first of each month to the
newsgroup BIONEWS/bionet.announce immediately following the posting of
the BIOSCI information sheet.


	       **** BIOSCI USER ADDRESS DIRECTORY ****

Please take this opportunity to add your name and address information
to the BIOSCI User Address Database if you have not already done so.

Below is the address form that we would like each reader of the
BIOSCI/bionet newsgroups to complete and return if you would like to
be listed in our database.  The database serves as a directory that
enables biologists, who are currently using (or even just reading) the
BIOSCI newsgroups, to look up e-mail addresses and other information
about our users.

The address database is reindexed nightly for WAIS and waismail access
(waismail is our WAIS e-mail server, more below) and will also be
available for access via other gopher sites if they wish to permit it.
The raw unindexed data is available for FTP from net.bio.net and is
atomized sufficiently to allow import into your local RDBMS should you
so desire.

Please carefully follow the instructions for completing the form
below and return it to either of the following two addresses
(whichever is more convenient for you).  Thanks in advance for taking
the time to complete and return the form.

Addresses for returning forms         Location        Network
-----------------------------         --------        -------
biovote@net.bio.net                   U.S.A.          Internet/BITNET
biovote@daresbury.ac.uk               U.K.            JANET


	     MAKING SURE THAT YOUR INFORMATION IS CURRENT

This notice will be mailed bimonthly to each newsgroup.  You should
check our WAIS source or waismail e-mail server from time-to-time to
see if your address information is still up-to-date.  Send the message

help

to waismail@net.bio.net for instructions on using waismail.  Leave the
Subject: line in your message blank.


		  Using Gopher to complete the form
                  ---------------------------------

If you don't want to use a text editor, you can also use Dan
Jacobson's gopher site to fill out the address database form as
follows.  Otherwise skip this section on gopher and proceed to the
instructions for filling out the form below.

> To add yourself to the database just point your
> gopher client at merlot.gdb.org and select the following:
> 
> -->  15. Searching For Biologists/
> 
>  -->  9.  E-mail Addresses of Biosci-Bionet Users/
> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

> Europeans can point their gopher client at gopher.csc.fi and add their
> information to the database. All entries will be mailed directly to
> Dave for incorporation in a wais source.
> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


	    IMPORTANT INSTRUCTIONS - PLEASE READ CAREFULLY

Please enter all responses after the : on each line, leaving one (1)
blank space after the : (i.e., before the start of your text).

Please do NOT extend your responses past the end of each line (80
characters) or alter any of the field identifiers such as "first name: ". 
Several lines are provided at the end of the form for comments, but,
please adhere to the line length restriction.

On the date: line, please enter the date in the DD-MM-YY format, e.g.,
05-05-93 for 5 May 1993.  This line will tell others when the
information was last updated.  Please be sure to include the 0's for
single digit days or months, e.g., 05-05-93, not 5-5-93.

Note that the "e-mail network: " line below is for specifying, e.g.,
"Internet," "BITNET," "EARN," "JANET," or whatever other network that
your computer may be on.

If you are uncertain about any field, please feel free to leave it
blank, but please DO NOT DELETE the field identifier from the form!

In the first field below, "New information or Update ...", please
enter "N" if this is the first time that you have registered in the
directory or "U" if you are correcting a listing that you sent to us
previously.

The comment: lines may be used for anything that you like but PLEASE
DO NOT DELETE THEM FROM THE FORM OR ALTER THEM.  One suggested use is
to list the names of the newsgroups in which you participate.  Please
use the MAILING LIST name (see below - the latest version of the list
can be requested from biosci@net.bio.net) instead of the USENET name
even if you don't participate by e-mail.  WAIS might get confused by
the periods in the USENET names.  This allows one to retrieve via WAIS
or waismail the list of participants in a particular group.

For example:

comment: ARABIDOPSIS PLANT-BIOLOGY BIONEWS

On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIO-SOFTWARE               bionet.software
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

Listing newsgroups on the comment: line is optional, of course.

Thanks again for your cooperation!



--------------- please cut here and return portion below ---------------

New information or Update to old record (enter N or U): 
date (DD-MM-YY): 
first name: 
middle initial: 
family name: 
job title: 
e-mail address: 
e-mail network: 
phone number: 
FAX number: 
institution: 
address1: 
address2: 
address3: 
city: 
state/province: 
country: 
postal code: 
research interest: 
research interest: 
comment: 
comment: 
comment: 
comment: 
comment: 

