From owner-acedb@net.bio.net Tue Feb 08 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!agate!overload.lbl.gov!acedbfaq
From: acedbfaq@s27w007.pswfs.gov (ACEDB FAQ Pseudouser)
Newsgroups: bionet.software.acedb,news.answers
Subject: ACEDB Genome Database Software FAQ
Followup-To: bionet.software.acedb
Date: 9 Feb 1994 17:41:55 GMT
Organization: Dendrome, A genome database for forest trees
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Summary: Frequently Asked Questions about finding and getting
 started with the database system ACEDB.  ACEDB is used
 to collect information regarding the molecular biology
 of the genome.
Archive-name: acedb-faq
Last-modifed: 2/9/94
Version: 1.8
Xref: biosci bionet.software.acedb:154 news.answers:12475

----------------------------------------------------------------------
Common Questions and Answers about ACEDB.

    This document will be posted monthly to the BIOSCI newsgroup
    bionet.software.acedb and to USENET conference news.answers.
    It is intended to be used as an index to ACEDB databases and
    to information about the database software.

    The latest version of the ACEDB FAQ should be available via
    anonymous ftp at machine net.bio.net (134.172.2.69) as
    file pub/BIOSCI/ACEDB/ACEDB.FAQ or at rtfm.mit.edu
    (18.70.0.209) as pub/usenet.news.answers/acedb-faq. Answer 3
    demonstrates a sample FTP session.  If you only have
    electronic mail, the FAQ can be retrieved from
    mail-server@rtfm.mit.edu.

    There is an HyperText Markup Language (HTML) version of this
    document available on the World Wide Web:
        http://probe.nalusda.gov:8000/plant/acedbfaq.html
    [Until I get more familiar with HTML, it may not be totally
     synchronized with the plain FAQ. --bks]

    Curators of ACEDB databases should take note of Question 4 and
    keep me apprised of changes.

    Errors of commission or omission are unintentional.  If I have
    forgotten to give you credit please let me know.  Please
    send comments and corrections to: acedbfaq@s27w007.pswfs.gov
        --Bradley K. Sherman 

----------------------------------------------------------------------
The List of questions in the ACEDB FAQ.  Questions marked with
+ are new, those with ! have substantially changed answers:

Q0:  What is ACEDB?
Q1:  What is the current version of ACEDB?
Q2:  What hardware|software do I need to run ACEDB?
Q3:  Where can I get ACEDB?
Q4:  !What ACEDB databases exist?
Q5:  What written documentation exists for ACEDB?
Q6:  Where can I find further information about ACEDB?
Q7:  How should ACEDB be cited?
Q8:  Is ACEDB object-oriented?
Q9:  What's all this about Gopher|WAIS|Anonymous ftp|WWW|URL ...
Q10: How can I get on the ACEDB announcements mailing list?
Q11: !When and where is the next ACEDB Workshop?
Q411:Who contributed to this document?

----------------------------------------------------------------------
Q0:  What is ACEDB?

A0:  ACEDB is an acronym for A Caenorhabditis elegans Database.  It can
     refer to a database and data concerning the nematode C. elegans,
     or to the database software alone.  This document is concerned
     primarily with the latter meaning.  ACEDB is being adapted by many
     groups to organize molecular biology data about the genomes of
     diverse species [see Q4].

     ACEDB allows for automatic cross-referencing of items during
     loading and allows for hypertextual navigation of the links
     using a graphical user interface and mouse.  Certain special
     purpose graphical displays have been integrated into the
     software.  These reflect the needs of molecular biologists
     in constructing genetic and physical maps of genomes.

     ACEDB was written and developed by Richard Durbin (MRC LMB
     Cambridge, England) and Jean Thierry-Mieg (CNRS, Montpellier,
     France), beginning circa 1990.  It is written in the C programming
     language and uses the X11 windowing system to provide a platform
     independent graphical user interface.  The source code is publicly
     available [See Q3].  Durbin & Thierry-Mieg continue to develop
     the system, with contributions from other groups including
     Lawrence Berkeley Laboratory and the European integrated Genome
     Project.

     A description by Durbin & Thierry-Mieg:
         ACEDB does not use an underlying relational database
         schema, but a system we wrote ourselves in which data
         are stored in objects that belong in classes.  This is
         nevertheless a general database management system using
         caches, session control, and a powerful query language.
         Typical objects are clones, genes, alleles, papers,
         sequences, etc.  Each object is stored as a tree,
         following a hierarchical structure for the class (called
         the "model").  Maps are derived from data stored in tree
         objects, but precomputed and stored as tables for
         efficiency.  The system of models allows flexibility
         and efficiency of storage -missing data are not stored.
         A major advantage is that the models can be extended
         and refined without invalidating an existing database.
         Comments can be added to any node of an object.
         Current display modes are:
             TREE   for text type objects: papers, authors, genes
             etc.
             GMAP   genetic map
             PMAP   physical map (Sulston contig style)
             SEQ    DNA sequence - symbolic, features, sequence
             and translation
             GRID   hybridisation patterns for a probe to a clone
             grid
             BIBLIO bibliography attached to any object display
             modules under development:
             CMAP   whole chromosome physical map plot
             GEL    agarose gel simulation derived from sequence

----------------------------------------------------------------------
Q1:  What is the current version of ACEDB?

A1:  As of January 1994, ACEDB has undergone a bifurcation.  Those
     involved with C. elegans will want to to track the 2.x series
     under the stewardship of Richard Durbin and all other groups
     should probably track the 3.x series of Jean Thierry-Mieg.
     Thierry-Mieg writes "... 2 and 3 differ only at the level of
     displays ..."  Version 2.0 was released in December, 1993 and
     version 3.0 was released in January, 1994.
 
     To retrieve the software see Q3.

     To be kept informed of new releases see Q10.

     [This question refers to the software not the C. elegans data.]

----------------------------------------------------------------------
Q2:  What hardware/software do I need to run ACEDB?

A2:  ACEDB currently runs on the following Unix systems, under X11:
     Unix:
         Any machine running SunOS 4.x
             e.g. Sun SPARCstation 1, 1+, 2, IPC, IPX.
         SPARCstation 10 under Solaris [Probably all Solaris, then --bks]
         DEC  DECstation3100, 5100 etc.
         DEC  Alpha/OSF-1
         Silicon Graphics Iris series
         PC 386/486 with Linux (free Unix)
        There exist, or have existed, ports onto Alliant, Hewlett-
        Packard, IBM R6000, NeXT, Convex.   You may have to contact
        the developer responsible for the port to make these real.
    MSDOS/Windows/NT:
        A port to NT is rumored to be in the works.
    Macintosh:
        A port to the Macintosh may become available real soon now.

    For cost savings, a combination of a high-end Intel platform
    with Linux appears very attractive.

    Here at the Institute of Forest Genetics we run ACEDB on a 
    Sun Microsystems SPARCstation II, and users can interact
    using Macintoshes and PC-clones by using X11 implementations
    for the personal computers and a LAN.  [This section should
    be expanded to have a more thorough discussion of X11
    interactions.  --bks]

----------------------------------------------------------------------
Q3:  Where can I get ACEDB?

A3:  All the files are available in the following public access
     accounts (anonymous ftp sites) accessible via Internet:
        lirmm.lirmm.fr (193.49.104.10) in pub/acedb
        cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb
        ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb
        bioinformatics.weizmann.ac.il (132.76.55.12) in
            pub/databases/acedb.

    A typical session would be:
        ftp ncbi.nlm.nih.gov
        login: anonymous
        password: your email address
        cd repository/acedb/ace3
        binary
        ls
        get README_3
        get NOTES
        get INSTALL
        get bin.sparc.3.0.tar.Z
        quit

----------------------------------------------------------------------
Q4:  What ACEDB databases exist?

A4:  [In alphabetic order by Database name --bks]

     Database : AAnDB-1.0
     Species : Aspergillus nidulans
     PI : Leland Ellis
     Last_update : Sept. 1993
     ACEDB_version : 2.0
     URL : http://keck.tamu.edu/ibt.html

     Database : AAtDB
     Species : Arabidopsis thaliana
     Availability : 
     Curator : John Morris
     Current version: 1-5
     Contact : curator@frodo.mgh.harvard.edu
     Last_update : Sept. 1993

     Database : ABtDB-1.0
     Species : Bovine, Bos taurus
     PI : Leland Ellis
     Last_update : Sept. 1993
     URL : http://keck.tamu.edu/ibt.html

     Database : ACeDB
     Species : Caenorhabditis elegans
     Availability :
     Current version: 1-21
     Curator : Jean Thierry-Mieg
     Curator : Richard Durbin
     Contact : rd@mrc-lmb.cam.ac.uk
     Contact : mieg@kaa.cnrs-mop.fr
     Last_update : Sept. 1993

     Database : ChlamyDB
     Species : Chlamydomonas
     PI : Elizabeth Harris
     Contact : chlamy@acpub.duke.edu
     Availability : Still under construction
     Last_update : 30 Sept. 1993

     Database : EcoDB
     Species : E. coli
     PI : Staffan Bergh
     Contact : staffan@biochem.kth.se
     Availability : Still under construction
     Last_update : 11 Oct. 1993

     Database : FlyBase
     Species : Drosophila melanogaster
     Availability : gopher or gopher+ ftp.bio.indiana.edu
     Availability : ACeDB-style interface to SyBase server
                    due by end of 1994
     Curator : Edward Welbourne
     Contact : eddy@gen.cam.ac.uk
     Contact : flybase@morgan.harvard.edu
     PI : William Gelbart
     PI : Michael Ashburner
     PI : Thomas Kaufman
     PI : Kathy Matthews
     PI : John Merriam

     Database : Flydb
     Species : Drosophila melanogaster
     Availability : by request only, via ftp
     Curator : Suzanna E. Lewis
     Contact : SELewis@lbl.gov
     Focus : STS content mapping project summary
     PI : Gerald Rubin
     PI : Mike Palazzolo
     PI : Dan Hartl
     PI : Alan Spradling
     Last_update : Sept. 1993

     Database : GrainGenes
     Species : Wheat, barley, oats, relatives
     Availability : Gopher greengenes.cit.cornell.edu port 70
     Availability : ACEDB version by ftp, on request from the curators
     Curator : David E. Matthews
     PI : Olin D. Anderson
     Contact : matthews@greengenes.cit.cornell.edu
     Contact : oandersn@wheat.usda.gov
     Last_update : Sept. 1993

     Database : human.c17
     Species : Homo sapiens
     Availability :  the database is under development
     Contact : lsprilus@weizmann.weizmann.ac.il
     Focus :  mapping & sequencing of Human Chromosome 17
     Based_on: acedb.3-0
     Last_update : Jan. 1994

     Database : Mace
     Species : Zea mays L. ssp. mays
     Focus : Maize genome
     Comment : Mace is the front end for maizedb, a relational
               (SYBASE) database. It is updated from maizedb by
               software written by Stan Letovsky.  Maizedb is
               updated daily and will soon be accessible by
               public login.
     Curator : Ed Coe 
     Curator : Pat Byrne
     Curator : Georgia Davis
     Curator : Mary Polacco
     Off-Site Curator : Marty Sachs 
     Off-Site Curator : Christiane Fauron 
     Off-Site Curator : Carolyn Wetzel
     Off-Site Curator : Steve Rodermel 
     Off-Site Curator/Designer : Stan Letovsky 
     Off-Site Curator/Designer : Mary Berlyn 
     Systems Manager : Denis Hancock
     PI : Ed Coe
     Contact : maizedb@teosinte.agron.missouri.edu
     Last_update: 5 October 1993

     Database : MycDB
     Species : Mycobacterium
     PI : Staffan Bergh
     PI : Thierry Garnier
     Contact : staffan@pasteur.fr
     Last_update : Sept. 1993

     Database : RiceGenes
     Species : Rice (O. sative)
     Availability : under development, login at own risk
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SolGenes
     Coverage: Solanaceae - tomato, potato, pepper (eventually)
     Availability : Beta ACEDB via login or tar file
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SoyBase
     Species : Soybeans
     Curator :  Lisa Lorenzen
     PI : Randy Shoemaker
     Contact : lorenzen@mendel.agron.iastate.edu
     Last_update : Sept. 1993

     Database : TreeGenes
     Species : Forest trees, Pinus taeda
     Availability : contact curator
     Curator : Bradley K. Sherman
     PI : David B. Neale
     Contact : Dendrome@s27w007.pswfs.gov
     Contact : bks@s27w007.pswfs.gov
     Contact : dbn@s27w007.pswfs.gov
     Last_update : Sept. 1993

     Database : 21Bdb
     Species : Homo sapiens
     Availability : by request, via ftp, gopher
     Curator : Donn F. Davy
     Contact : DFDavy@lbl.gov
     Contact : aggarwal@genome.lbl.gov
     Focus : STS content mapping & sequencing of Human Chromosome 21
     PI : Jasper Rine
     PI : Michael Palazzolo
     PI : Chris Martin
     PI : Jan-Fang Cheng
     Last_update : Sept. 1993

     Database : VoxPop
     Species : Populus spp.
     Availability : contact curator
     Curator : Carl G. Riches
     PI : Reinhard F. Stettler
     Contact : cgr@poplar1.cfr.washington.edu
     Contact : STETTLER@coyote.cfr.washington.edu
     Last_update : Sept. 1993

     Database : ?
     Species : Sorghum
     PI : Leland Ellis
     Last_update : Sept. 1993

     Database : ?
     PI : Scott Chasalow
     Species : Potato
     Contact : Scottish Crop Institute, Dundee
     Last_update : Sept. 1993

     Database : ?
     PI : George Murphy
     PI : David Flanders
     Species : Arabidopsis thaliana
     Contact : John Innes Center, Norwich, England
     Last_update : Sept. 1993

     Database : ?
     Species : Homo sapiens
     Focus : Physical mapping of human chromosomes 22 and X
     Curator : Ian Dunham
     Contact : idunham@crc.ac.uk id1@sanger.ac.uk
     PI : Ian Dunham
     PI : David Bentley
     Last_update : 28 Sep 1993

     [Curators:  Please submit an entire paragraph in
      this format for inclusion or update. --bks]


----------------------------------------------------------------------
Q5:  What written documentation exists for ACEDB?

A5:  The primary documents are included in the Software
     distribution in the wdoc subdirectory:
         acedb -- A C. elegans Database: I. Users' Guide.
         acedb -- A C. elegans Database: II. Installation Guide.
         acedb -- A C. elegans Database: III. Configuration Guide.
         Syntactic Definitions for the ACEDB Data Base Manager
             --Jean Thierry-Mieg and Richard Durbin (1991-)
     You will find other interesting documents in the wdoc subdirectory.

     By anonymous ftp from ncbi.nlm.nih.gov (130.14.20.1)
     in repository/acedb:
        doc.1_9.tar.Z

     Cherry, J.M., Cartinhour, S.W., and Goodman, H.M. (1992) AAtDB,
     An Arabidopsis thaliana Database. Plant Molecular Biology Reporter
     10 (4): 308-309,409-410

     Tutorial manual for AAtDB:
     Cartinhour, S., Cherry, J.M., and Goodman, H.M. (1992) An
     Introduction to ACeDB: For AAtDB, An Arabidopsis thaliana
     Database. Massachusetts General Hospital. (Available on
     request in printed form from the AAtDB curator).

     A description of ACEDB:
     Cherry, J.M. and Cartinhour, S.W. (1993) ACEDB, A tool for
     biological information. in Automated DNA Sequencing and
     Analysis, edited by M.  Adams, C. Fields, and C. Venter.
     Academic Press (in press).  [text is available through
     ftp or gopher from weeds.mgh.harvard.edu]

     Another description of ACEDB for physical mapping projects:
     Dunham, I., Durbin, R., Mieg, J-T & Bentley, D.R. (1993)
     Physical mapping projects and ACEDB, in Guide to Human
     Genome Computing. Ed.  Bishop, M.J.  (Academic Press)
     (review, in press).  [text is available through ftp or
     gopher from weeds.mgh.harvard.edu]

----------------------------------------------------------------------
Q6:  Where can I find further information about ACEDB?

A6:  There is a Usenet/Biosci conference titled bionet.software.acedb.
     If you do not have access to the Biosci conferences via a
     newsreader (e.g. rn, trn) you can participate in the conference
     by electronic mail.  To subscribe to the e-mail version of the
     conference send email to biosci-server@net.bio.net (UK, European
     readers use biosci@uk.ac.daresbury or biosci.daresbury.ac.uk) with
     no subject line and only the message
           subscribe ACEDB-SOFT
     in the body.  To unsubscribe send the message
           unsubscribe ACEDB-SOFT
     to the same address.
     This is an automated service.  Your e-mail address will be taken
     from the header of the message that you send.  If you then send
     mail to acedb@net.bio.net the mail will be distributed to all
     subscribers and to the electronic conference.

     Mike Cherry has set up an ACEDB Developer's archive.  For
     anonymous ftp use the hostname weeds.mgh.harvard.edu and look in
     the acedb_dev directory. If you wish to contribute you can put
     files in the incoming directory.  Send a message to Mike
     (cherry@genome.stanford.edu) that you have put something in that
     directory then Mike will move it out for general access.
     For gopher you can connect to weeds.mgh.harvard.edu
     (132.183.190.21) and ...
        -->  N.  FTP Archives for Molecular Biology/
     then
        -->  M.  ACEDB Developer's archive/
     [N and M are integers which are subject to change.]

     The bionet.software. acedb.conference is archived and can be
     searched using WAIS.  Here is a Gopher-style link to the WAIS
     archive. (This is also courtesy of Mike Cherry.):
          #
          Type=7
          Name=ACEDB BioSci Electronic Conference
          Path=7/.index/acedb-biosci
          Host=genome-gopher.stanford.edu
          Port=70

     The AAtDB, Soybase, GrainGenes, Mace, and TreeGenes (see Q4)
     databases regularly submit data to the Plant Genome Database
     at the National Agricultural Library (NAL).  Nal makes this
     data available via the WWW using an http server with URL:
         http://probe.nalusda.gov:8000/index.html
     You will also find a selection of models.wrm files (schemata)
     for the various databases here.  You will want to get a
     "mosaic client" to examine this.

     Other URL's that readers with mosaic clients might want to
     examine are:
        http://moulon.inra.fr/acedb/acedb.html for C. elegans data
        http://moulon.inra.fr/acedb/mycdb.html for Mycobacterium data
        http://mouIon.inra.fr:8001/acedb/igd.html for an integrated
            genome database.
     For information on how these were created see
        http://moulon.inra.fr/acedb_conf_eng.html"
        http://moulon.inra.fr/acedb_conf.html (en francais)

     The Genome Computing Group, Lawrence Berkeley Laboratory
     has an anonymous ftp service at machine genome.lbl.gov
     (131.243.224.80) which contains:
          flydb - LBL's Drosophila Acedb-style database
          21bdb - LBL's Human Chromosome 21 Acedb-style database
          querdb - LBL's query-language extensions to Acedb 
          metadata - LBL's compendium of Acedb database schema variants
          macace-aatdb-demo.hqx  -  pre-release Acedb MacIntosh version
          There is also a repository of contributed software for
          data conversions and the like.

     Computer staff for the UC Berkeley Drosophila physical mapping
     project the LBL Human Chromosome 21 project, and the LBL plant
     genome projects meet regularly to coordinate their ACEDB
     extension and development efforts, along with Frank Eeckman,
     who is working on the Macintosh version of ACEDB (for further
     information, contact jlmccarthy@lbl.gov). They also keep in
     close touch (via email, personal visits, etc.) with their
     counterparts in Cambridge (Richard Durbin et al), Montpellier 
     Jean Thierry-Mieg et al), and the Interated Genome Database
     project in Heidelburg (Otto Ritter, Detlef Wolf et al).

----------------------------------------------------------------------
Q7:  How should ACEDB be cited?

A7:  From the distribution:

        We realize that we have not yet published any "real" paper on
        ACEDB.  We consider however that anonymous ftp servers are a
        form of publication. We would appreciate if users of ACEDB
        could quote:
            Richard Durbin and Jean Thierry Mieg (1991-). A C. elegans
            Database.  Documentation, code and data available from
            anonymous FTP servers at lirmm.lirmm.fr,
            cele.mrc-lmb.cam.ac.uk and  ncbi.nlm.nih.gov.

        Papers involved in database development could quote more
        precisely:
           I.   Users' Guide. Included as part of the ACEDB distribution
         kit,
           II.  Installation Guide. Included as part of the ACEDB
         distribution
           III. Configuration Guide. Included as part of the ACEDB
         distribution

        and the preprintkit, available by Anonymous FTP from ...
           Jean Thierry-Mieg and Richard Durbin (1992). Syntactic
           Definitions for the ACEDB Data Base Manager. Included as
           part of the ACEDB distribution.

             --Jean and Richard.

----------------------------------------------------------------------
Q8: Is ACEDB object-oriented?

A8: From the ACEDB User's Guide.

    A major current vogue in computer languages and database design
    is for ``object-oriented'' systems.  It's also a source of lots
    of argument.  We are just trying to build a good system, and
    don't want to get caught in the crossfire, but we do talk about
    organising our data into objects and classes.  We have undoubtedly
    been influenced by many of the ideas going around, but it isn't
    likely our system would be regarded as kosher by the object-
    oriented community.  In particular there is no class hierarchy, nor
    inheritance, and it is written in a modular but non-ideological way
    in straight C. However display and disk storage methods are class
    dependent.

    In some ways the class hierarchy is replaced by our system of
    models and trees, which seems to be rather unusual.  We think it
    is very natural for the representation of biological information,
    where for some members of a class a lot might be known about some
    aspect, but for most only a little is known.

    The advantages of our sytem over a relational database, such as
    Oracle or Sybase, is our ability to refine our descriptions without
    rebuilding the database and the possibility of organising the
    storage of data on disk according to their class, i.e. we store in
    a very different way the tree-objects and the long stretches of
    DNA sequence.

----------------------------------------------------------------------
Q9:  What's all this about Gopher/WAIS/Anonymous ftp/WWW ...

A9:  These terms all refer to Internet protocols.
     An excellent introduction to the Internet is:
       _The Whole Internet User's Guide & Catalog_,
       by Ed Krol, O'Reilly & Associates, 1992.
     Or ask your system administrator to provide you with
     a gopher client or mosaic client and begin navigating
     on your own. 

----------------------------------------------------------------------
Q10: How can I get on the ACEDB announcements mailing list?

A10: To get on or off the mailing list send mail to
     rd@mrc-lmb.cam.ac.uk or mieg@kaa.cnrs-mop.fr.
     New releases of the software are announced to
     this list.

----------------------------------------------------------------------
Q11: When and where is the Next ACEDB Workshop?

Q11: From Jean Thierry-Mieg:
     DATES:
     The acedb '94 workshop will be held july 2 to 16, in Saint Matthieu
     de Treviers, a small village, 20 km north of Montpellier, at the
     foot of the Pic Saint Loup.

     HOUSING:
     We have booked a place meant for family vacations which includes
     ample space, a nice conference room and ten studios meant for 5
     people (bathroom, shower, kitchenette, terrace, all nice and clean)
     that we plan to share among 3 to 4 participants.  Meals will be
     taken at a local restaurant.

     The place is ideal for work and informal discussions and will be
     well equiped with computers. The situation is nice for hiking and
     allows volley-ball, ping-pong, tennis and petanque.

     We can provide lists of possible hotels for those who would prefer
     more privacy or find ways of accomodating families if you let us
     know very soon (school ends early july in France).

     Cost for 2 weeks is 1000 FF (about 200 US dollars) for housing on
     site plus 2500 FF for full meals. We may get enough funding to
     reduce this cost, but cannot pay for travel.

     PROGRAM:
     Formal presentations and general discussions will take place in the
     mornings and the evenings, alternating network aspects, data handling,
     displays and genome data analaysis.

     The afternoons will be dedicated to data manipulation, programming
     and writing documentation. The idea is to actually implement during
     the meeting many of the ideas that will come up, to fuse and
     coallesce the now numerous acedb-based applications into a working
     modular package, and to import and consolidate large sets of
     additional data.

     Towards this goal, we will broadcast the following announcement

     ACEDB'94 Genome Database Workshop.

     Montpellier, July 2-16, 1994

     This meeting will cover the use and development of the 
     ACEDB database manager central to several major genome projects,
     including C.elegans, A.thaliana, human, and a number of
     other plant and animal species. 

     We wish to encourage people with large sets of data on other
     organisms to attend this workshop. They will be helped to build,
     during the meeting, a friendly graphic presentation of their own
     data, in return for discussing their own experience.

     *******************************************************************

     FORMAT:
     This meeting will be much longer than the 2 previous acedb workshops
     (Cambridge 92 and Boston 93), in the hope of initiating new
     collaborations and allowing concrete results. This format is usual in
     physics summer schools and often very productive.
     
     The workshop may be coupled to a 2 days presentation of acedb, open
     to the general audience, and yet to be organised.
     
     We anticipate at least the participation of people from: Berkeley,
     Boston, Cambridge, Heidelberg and Montpellier, including Richard
     Durbin (LMB and Sanger Centre, Cambridge), John McCarthy (LBL,
     Berkeley), Otto Ritter (DKFZ, Heidelberg), Danielle and Jean
     Thierry-Mieg (CNRS, Montpellier).

     Please confirm your participation and forward this announcement to
     your colleagues.

     Danielle and Jean Thierry-Mieg 
     CNRS-CRBM
     BP 5051,
     34033  Montpellier, France.

     email mieg@kaa.cnrs-mop.fr
      (if this address fails, fall back on mieg@ncbi.nlm.nih.gov)

     Tel: (33) 67 61 33 24
     Fax: (33) 67 52 15 59

----------------------------------------------------------------------
Q411:Who contributed to this document?
     [Note to international readers: 411 is the phone number for
     information in the USA. --bks]

A411: Major contributions in getting this FAQ off the ground
      were made by John McCarthy and Mike Cherry.  Other
      contributors include:
        Lisa Lorenzen
        David Matthews
        Edie Paul
        Donn Davy
        Eric De Mund
        Sam Cartinhour

      To add or modify information in this document, please
      send mail to: acedbfaq@s27w007.pswfs.gov

      Bradley K. Sherman
      Dendrome Project                
      Institute of Forest Genetics    
      P.O. Box 245, Berkeley, CA, 94701
      Phone: 510-559-6437 Fax: 510-559-6440  

      The Dendrome Project and TreeGenes are funded by the
      USDA-ARS Plant Genome Database Project.

---------------------End of file acedb-faq----------------------------

From owner-acedb@net.bio.net Tue Feb 08 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!agate!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: ACEDB Genome Database Software FAQ
Date: 9 Feb 1994 21:36:40 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 17
Message-ID: <2jbl18$om3@overload.lbl.gov>
References: <2jb793$k8t@overload.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov


Curators of ACEDB databases who also offer gopher, http or other
Internet services might want to reformulate their paragraphs
in the ACEDB FAQ to include URL's.

This will help me to construct the HTML version of the
FAQ.

URL's are Universal Resource Locators and are a component
of the World-Wide Web project.

    --bks
-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Tue Feb 08 22:00:00 1994
Path: biosci!bcm!news.tamu.edu!128.194.15.2!leland
From: leland@straylight.tamu.edu (Leland Ellis)
Newsgroups: bionet.software.acedb
Subject: WWW-AAnDB and WWW-ABtDB
Date: 09 Feb 1994 19:05:56 GMT
Organization: W.M. Keck Center for Genome Informatics, Institute of Biosciences
	and Technology, Texas A&M University, Houston
Lines: 86
Distribution: world
Message-ID: <LELAND.94Feb9130557@straylight.tamu.edu>
NNTP-Posting-Host: straylight.tamu.edu


		       WWW-AAnDB and WWW-ABtDB

	      WWW-ACeDB Servers for Aspergillus and Cows

			   available on the

			      WWW Server

				of the

       W.M. Keck Center for Genome Informatics at the Institute
		      Biosciences and Technology
			 Texas A&M University
			       Houston

		  URL: http://keck.tamu.edu/ibt.html

WWW-AAnDB-1.0 is an experimental WWW interface to the data contained
in AAnDB-1.0 (implemented in ACeDB-3.0, the latest version of Richard
Durbin and Jean Thierry-Mieg's ACeDB) and is a prototype for a
database with datatypes useful in the study of Aspergillus nidulans
(and potentially other filamentous fungi).  It utilizes the elegant
ACeDB Server software (nph-acedb3) developed by Guy Decoux at
(decoux@moulon.inra.fr).  AAnDB-1.0 is a collaboration of Keck-IBT and
Tom Adams (Department of Biology, Texas A&M University) and Greg May
(Department of Cell Biology, Baylor College of Medicine).

WWW-ABtDB-1.0 is an experimental WWW interface to the data contained
in ABtDB-1.0, and is also implemented in ACeDB-3.0 and nph-acedb3.  It
also contains data for human homologs of bovine loci, with links
between species.  The data models provided in the Human Chromosome 21
ACeDB-3.0 by Otter Ritter and co. were a very useful starting point to
use for both new bovine Tags, as well as the addition of homolog
functionality.  ABtDB-1.0 is a collaboration of Keck- IBT and Jim
Womack (College of Veterinary Medicine, Texas A&M University).

Both of these WWW-ACeDB servers are accessible via the WWW Server of
Keck-IBT.  This URL

http://keck.tamu.edu/ibt.html

will take you to the Keck-IBT HomePage -- clicking on the Keck-IBT
logo takes you to our 1st page of information.

The link

What's New on the Keck-IBT WWW Server

leads to an ever-changing page which serves as a running dialog of our
experimentation with this interface, and has links to both
WWW-AAnDB-1.0 and WWW-AAnDB-1.0, as well as to further information and
references about what is in the databases.  Also, Jeff Kirk
(jkirk@keck.tamu.edu) has put together a Tutorial on how these Servers
were set up, with pointers to where the components can be found.

Both WWW servers should be regarded as experimental prototypes -- they
do work, and we find them useful, but the data models are being
experimented with daily, and new data is always being added.  Finally,
neither db is anywhere near comprehensive in the data included, but is
illustrative of the datatypes that we routinely use in the study of
these organisms.

Any feedback is very welcome at:

leland@straylight.tamu.edu or jkirk@keck.tamu.edu

Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL:   http://keck.tamu.edu/ibt.html
--
Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL:   http://keck.tamu.edu/ibt.html

From owner-acedb@net.bio.net Tue Feb 08 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: ACEDB update 2-9 data for C. elegans
Date: 9 Feb 1994 18:51:56 -0000
Lines: 157
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2jbbcc$4rh@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk


This is a broadcast message to the ACEDB mailing list.  If you do not
want to be on the list, please send email to rd@mrc-lmb.cam.ac.uk.

ACEDB data update 2.9
=====================

There is available a new data update for the C. elegans database.
This does not affect version 3 of ACEDB, which is designed for human
and other organism data.

We plan to have an incremental data update every month, with code
updates every three months.  The quarterly updates may also contain
more complete data, e.g. the genetic map locations have not been
updated in this version, although there is more mapping data.  We
tentatively plan a map revision for the March release.  We also have
not updated the file of matching proteins (proteins.2-8.tar.Z).

********************************************************************
IMPORTANT: you must get a new copy of INSTALL as well as the update.
********************************************************************

The main items in this data release are:
       Physical map 18/1/94	
       C. elegans DNA sequences in EMBL release 36
       Mapping data sent to cgc@mrc-lmb.cam.ac.uk
       Latest CGC strain and subscriber listings and bibliography
       Abstracts and keywords for many papers
       27 cosmid sequences from the genomic sequencing project
       General edits and fixes (e.g. yk* clones are now on the pmap)
       Cell lineage and fates
       Neural wiring data

The last two items are entirely new.  The cell lineage data is
currently preliminary.  What we have comes from combining files from
Barney Hilken and Thomas Burglin (thank you Thomas).  Currently we
have division times for embryonic divisions, but not postembryonic
ones.  Does anybody have these?  There is no tool to draw the lineage,
but we are thinking about it.

The neural wiring data come from two ring reconstructions (the JSH and
N2U series of White, Southgate, Thomson and Brenner, 1986).  For each
cell, there is a list the number of synapses of each type to each
target in each reconstruction.  Types Send, Send_joint, Receive,
Receive_joint refer to chemical synapses; the "_joint" variants
indicate that more than one potential post-synaptic partner was
present at the synapse (see White et al. for further explanation).
The other type, "Gap_junction" refers to a potential direct electrical
junction.  I have a memory that the Send and Receive numbers don't
exactly crosscheck - I haven't checked recently.

Remember that you can search all the abstracts (CGC, Worm Meeting and
now for many papers) using the "Long Search" button.

Code
====

There is no new code release.  You should use your existing version of
the binary (2_0).

		******	IMPORTANT  ******

There is a bug in version 2_0 of the code that causes the program to
crash ("bus error" or "segmentation violation") in some versions of
the binary (particularly sparc) at the very end of reading the
updates.  This does not lose any data.  It does remove the
precalculation of the genetic and physical maps, which should speed up
their display.  You can do this precalculation by hand as follows:

After adding the update, as the administrator (the person who
installed ACEDB)
	Select "Write Access" from the main menu
	Select "Align Maps" from the main menu
	Press the "Make pMaps" button to make the physical maps
	Press the "Make gMaps" button to make the genetic maps
	Select "Save" from the main menu.

Solaris versions
================

There are two Solaris versions, one for people with more recent
Solaris releases that contain the X11R5 libraries
(bin.solaris.2_0.tar.Z) and one for older releases with the X11R4
libraries (bin.solaris.2_0A.tar.Z).

Macintosh version
=================

There is now a tested Macintosh version.  You need a Macintosh with
16Mb of memory and a decent monitor.  You also need some way of
obtaining the files from an ftp site (e.g. NCSA telnet, Versaterm
Pro...) and Stuffit Deluxe, which I am told costs $65 in the USA, and
is useful anyway for compressing/decompressing files.  It turns out
that Stuffit Deluxe can decompress Unix .tar.Z archive files.  Frank
Eeckman has now made available a .tar.Z archive of a complete C.
elegans ACEDB database, with updates already read in.  Ftp to 
genome.lbl.gov, folder pub/macace, and follow the instructions in
README.  Thank you Frank.

Instructions for obtaining updates/the whole thing
==================================================

All the files are available in the following public access accounts
(anonymous ftp sites) accessible over internet:

  ncbi.nlm.nih.gov (130.14.20.1) in the USA, in repository/acedb/ace2
  cele.mrc-lmb.cam.ac.uk (131.11.84.1) in England, in pub/acedb/ace2
  lirmm.lirmm.fr (193.49.104.10) in France, in directory genome/acedb/ace2

In each case, log in as user "anonymous" and give a user identifier
as password.  Remember to transfer the files in BINARY mode by
typing the word "binary" at the start of your ftp session.  Many
thanks to NCBI for letting us share in their excellent resource.

Example:

ftp ncbi.nlm.nih.gov
login: anonymous
password 'your email address'
cd repository/acedb/ace2
binary
mget *
get README  y/n   answer yes   etc
...
...

quit

If installing for the first time
--------------------------------
Get all the update tar.Z and read the files README and NOTES before
proceeding further.

If updating an existing system
------------------------------
Just get the last update.tar.Z file, plus INSTALL.

Always get a copy of the INSTALL script.  Move it and the .tar.Z files
into the home directory in which you are installing ACEDB.  Type
"source INSTALL". 

If you have a problem making the program work, look at the section
on problems in NOTES, and if that fails to help, let us know.

******************************************************************

Please send any comments, especially about anything you think is
wrong (program or data), to

Richard Durbin (rd@mrc-lmb.cam.ac.uk)		program
Mary O'Callaghan (moc@mrc-lmb.cam.ac.uk)	data

-------------------- end of message --------------------





From owner-acedb@net.bio.net Thu Feb 10 22:00:00 1994
Path: biosci!biosci!not-for-mail
From: leland@straylight.tamu.edu (Leland Ellis)
Newsgroups: bionet.mycology,bionet.software.acedb,bionet.announce,comp.infosystems.www
Subject: WWW-AAnDB and WWW-ABtDB
Date: 10 Feb 1994 16:06:31 -0800
Organization: W.M. Keck Center for Genome Informatics, Institute of Biosciences
	and Technology, Texas A&M University, Houston
Lines: 86
Sender: kristoff@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: world
Message-ID: <LELAND.94Feb8161721@straylight.tamu.edu>
NNTP-Posting-Host: net.bio.net
Xref: biosci bionet.mycology:322 bionet.software.acedb:158 bionet.announce:942 comp.infosystems.www:4817


		       WWW-AAnDB and WWW-ABtDB

	      WWW-ACeDB Servers for Aspergillus and Cows

			   available on the

			      WWW Server

				of the

       W.M. Keck Center for Genome Informatics at the Institute
		      Biosciences and Technology
			 Texas A&M University
			       Houston

		  URL: http://keck.tamu.edu/ibt.html

WWW-AAnDB-1.0 is an experimental WWW interface to the data contained
in AAnDB-1.0 (implemented in ACeDB-3.0, the latest version of Richard
Durbin and Jean Thierry-Mieg's ACeDB) and is a prototype for a
database with datatypes useful in the study of Aspergillus nidulans
(and potentially other filamentous fungi).  It utilizes the elegant
ACeDB Server software (nph-acedb3) developed by Guy Decoux at
(decoux@moulon.inra.fr).  AAnDB-1.0 is a collaboration of Keck-IBT and
Tom Adams (Department of Biology, Texas A&M University) and Greg May
(Department of Cell Biology, Baylor College of Medicine).

WWW-ABtDB-1.0 is an experimental WWW interface to the data contained
in ABtDB-1.0, and is also implemented in ACeDB-3.0 and nph-acedb3.  It
also contains data for human homologs of bovine loci, with links
between species.  The data models provided in the Human Chromosome 21
ACeDB-3.0 by Otter Ritter and co. were a very useful starting point to
use for both new bovine Tags, as well as the addition of homolog
functionality.  ABtDB-1.0 is a collaboration of Keck- IBT and Jim
Womack (College of Veterinary Medicine, Texas A&M University).

Both of these WWW-ACeDB servers are accessible via the WWW Server of
Keck-IBT.  This URL

http://keck.tamu.edu/ibt.html

will take you to the Keck-IBT HomePage -- clicking on the Keck-IBT
logo takes you to our 1st page of information.

The link

What's New on the Keck-IBT WWW Server

leads to an ever-changing page which serves as a running dialog of our
experimentation with this interface, and has links to both
WWW-AAnDB-1.0 and WWW-AAnDB-1.0, as well as to further information and
references about what is in the databases.  Also, Jeff Kirk
(jkirk@keck.tamu.edu) has put together a Tutorial on how these Servers
were set up, with pointers to where the components can be found.

Both WWW servers should be regarded as experimental prototypes -- they
do work, and we find them useful, but the data models are being
experimented with daily, and new data is always being added.  Finally,
neither db is anywhere near comprehensive in the data included, but is
illustrative of the datatypes that we routinely use in the study of
these organisms.

Any feedback is very welcome at:

leland@straylight.tamu.edu or jkirk@keck.tamu.edu

Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL:   http://keck.tamu.edu/ibt.html
--
Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL:   http://keck.tamu.edu/ibt.html

From owner-acedb@net.bio.net Fri Feb 11 22:00:00 1994
Path: biosci!NET.BIO.NET!biosci-help
From: biosci-help@NET.BIO.NET (BIOSCI Administrator)
Newsgroups: bionet.software.acedb
Subject: test of acedb@net.bio.net
Date: 12 Feb 1994 02:18:09 -0000
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 2
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <CMM.0.90.2.761019484.kristoff@net.bio.net>
Reply-To: biosci-help@net.bio.net
NNTP-Posting-Host: net.bio.net


test of acedb@net.bio.net

From owner-acedb@net.bio.net Fri Feb 11 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!uunet!altern!software
From: software@altern.com (software)
Subject: software
Message-ID: <1994Feb11.184330.25118@altern.com>
Organization: Altern B , Corp.
X-Newsreader: Tin 1.1 PL5
Date: Fri, 11 Feb 1994 18:43:30 GMT
Lines: 1



From owner-acedb@net.bio.net Mon Feb 14 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!parc!decwrl!ames!purdue!news.cs.indiana.edu!hh@pmantis.berkeley.edu
From: nobody@pmantis.berkeley.edu
Subject: (none)
Message-ID: <9402151415.AA20733@pmantis.berkeley.edu>
Sender: root@news.cs.indiana.edu (Operator)
Organization: Computer Science, Indiana University
Date: Tue, 15 Feb 1994 06:15:12 -0800
Remailed-By: Eric Hollander <hh@pmantis.berkeley.edu>
Lines: 88

::
subject: Introduction to Blacknet

Introduction to BlackNet


Your name has come to our attention. We have reason to believe you may be
interested in the products and services our new organization, BlackNet, has
to offer.

BlackNet is in the business of buying, selling, trading, and otherwise
dealing with *information* in all its many forms. 

We buy and sell information using public key cryptosystems with essentially
perfect security for our customers. Unless you tell us who you are (please
don't!) or inadvertently reveal information which provides clues, we have
no way of identifying you, nor you us. 

Our location in physical space is unimportant. Our location in cyberspace
is all that matters. Our primary address is the PGP key location:
"BlackNet<nowhere@cyberspace.nil>" and we can be contacted (preferably
through a chain of anonymous remailers) by encrypting a message to our
public key (contained below) and depositing this message in one of the
several locations in cyberspace we monitor. Currently, we monitor the
following location: the "Cypherpunks" mailing list (cypherpunks@toad.com).

BlackNet is nominally nondideological, but considers nation-states, export
laws, patent laws, national security considerations and the like to be
relics of the pre-cyberspace era. Export and patent laws are often used to
explicity project national power and imperialist, colonialist state
fascism. BlackNet believes it is solely the responsibility of a secret
holder to keep that secret--not the responsibilty of the State, or of us,
or of anyone else who may come into possession of that secret. If a
secret's worth having, it's worth protecting.

BlackNet is currently building its information inventory. We are interested
in information in the following areas, though any other juicy stuff is
always welcome. "If you think it's valuable, offer it to us first."

- trade secrets, processes, production methods (esp. in semiconductors)
- nanotechnology and related techniques (esp. the Merkle sleeve bearing)
- chemical manufacturing and rational drug design (esp. fullerines and
protein folding)
- new product plans, from children's toys to cruise missiles (anything on
"3DO"?)
- business intelligence, mergers, buyouts, rumors

BlackNet can make anonymous deposits to the bank account of your choice,
where local banking laws permit, can mail cash directly (you assume the
risk of theft or seizure), or can credit you in "CryptoCredits," the
internal currency of BlackNet (which you then might use to buy _other_
information and have it encrypted to your special public key and posted in
public place).

If you are interested, do NOT attempt to contact us directly (you'll be
wasting your time), and do NOT post anything that contains your name, your
e-mail address, etc. Rather, compose your message, encrypt it with the
public key of BlackNet (included below), and use an anonymous remailer
chain of one or more links to post this encrypted, anonymized message in
one of the locations listed (more will be added later). Be sure to describe
what you are selling, what value you think it has, your payment terms, and,
of course, a special public key (NOT the one you use in your ordinary
business, of course!) that we can use to get back in touch with you. Then
watch the same public spaces for a reply.

(With these remailers, local PGP encryption within the remailers, the use
of special public keys, and the public postings of the encrypted messages,
a secure, two-way, untraceable, and fully anonymous channel has been opened
between the customer and BlackNet. This is the key to BlackNet.)

A more complete tutorial on using BlackNet will soon appear, in plaintext
form, in certain locations in cyberspace.

Join us in this revolutionary--and profitable--venture. 


BlackNet<nowhere@cyberspace.nil>


-----BEGIN PGP PUBLIC KEY BLOCK-----
Version: 2.2

mQA9Ai1bN6oAAAEBgM98haqmu+pqkoqkr95iMmBTNgb+iL54kUJCoBSOrT0Rqsmz
KHcVaQ+p4vLIWlrRawAFEbQgQmxhY2tOZXQ8bm93aGVyZUBjeWJlcnNwYWNlLm5p
bD4=
=yOMI
-----END PGP PUBLIC KEY BLOCK-----


From owner-acedb@net.bio.net Tue Feb 15 22:00:00 1994
Path: biosci!mrc-lmb.cam.ac.uk!rd
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: release announcements
Date: 16 Feb 1994 17:38:59 -0000
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 7
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9402161730.AA17953@cele.mrc-lmb.cam.ac.uk>
NNTP-Posting-Host: net.bio.net


I strongly support Herzog's suggestion that all ACEDB derived database
releases and updates should be announced on this newsgroup.  I
discovered that the newsgroup was not on the C. elegans release
mailing list, so have just added it.

Richard Durbin

From owner-acedb@net.bio.net Tue Feb 15 22:00:00 1994
Path: biosci!daresbury!bioftp.unibas.ch!rc1.vub.ac.be!rc4!rherzog
From: rherzog@rc1.vub.ac.be (Herzog Robert (DBM))
Newsgroups: bionet.software.acedb
Subject: Getting aware of new AceDB files?
Date: 16 Feb 1994 15:25:28 GMT
Organization: Brussels Free Universities (VUB/ULB), Belgium
Lines: 12
Message-ID: <2jtdt8$kj7@rc1.vub.ac.be>
NNTP-Posting-Host: rc4.vub.ac.be
X-Newsreader: TIN [version 1.2 PL2]

Is there any possibility to systematically use this list to post announcement 
of available updates about ACeDB formatted biological databases?

I find the software tremendous, but am a bit frustrated about not being aware 
of updated files that must be flourishing everywhere in the many fields
where the AceDB  kind of database has been implemented.

Any comments ?

Herzog
EMBnet Belgium


From owner-acedb@net.bio.net Wed Feb 16 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!daresbury!bioftp.unibas.ch!biox!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Suitable configuration for ACEDB/WCS?
Message-ID: <doelz.761511063@biox>
Organization: EMBnet Switzerland [Basel]
Date: Thu, 17 Feb 1994 18:51:03 GMT
Lines: 15

We have been asked what hardware is needed to run the ACEDB system
and the WCS. In particular the latter, which prequisites are there in 
terms of OS, memory, disk usage? We have some workstations here running 
SGI's IRIX and DEC's Ultrix and OSF/1. Please mail me and I'll summarize 
if there is enough interest. 

Regards
Reinhard Doelz
EMBnet Switzerland

-- 
  +---------------------------+-------------------------------------------+
  |    Dr. Reinhard Doelz     | Tel. x41 61 2672247    Fax x41 61 2672078 |
  |      Biocomputing         | electronic Mail       doelz@urz.unibas.ch |
  |Biozentrum der Universitaet+-------------------------------------------+

From owner-acedb@net.bio.net Wed Feb 16 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!bcm!news.msfc.nasa.gov!sol.ctr.columbia.edu!news.kei.com!yeshua.marcam.com!zip.eecs.umich.edu!umn.edu!sunrayce.solar.umn.edu!roman
From: roman@sunrayce.solar.umn.edu (username)
Subject: OBJ ORIENTED PROG OOPS
Message-ID: <CLDMAq.1sC@news.cis.umn.edu>
Sender: news@news.cis.umn.edu (Usenet News Administration)
Nntp-Posting-Host: sunrayce.solar.umn.edu
Organization: University of Minnesota, Twin Cities
X-Newsreader: TIN [version 1.1 PL8]
Date: Thu, 17 Feb 1994 16:12:09 GMT
Lines: 9

We are working with genetic engineering companies customizing software
for theire particular need. We anly do Object Oriented Methodologies usin
C++ and Smalltalk.We are looking for more customers to develop custom
software for them or we will considere joint ventures or good ideas.
Winterfire software inc 244 w 7th st st paul mn 55102 
 tel 612 222 1734 fax 1625 roman herther...
 we have 6years of experience with oops..over 20 projects completed.
 we'd be happy to answer any questions without obligation on your part..thank you...


From owner-acedb@net.bio.net Wed Feb 16 22:00:00 1994
Path: biosci!GENOME.STANFORD.EDU!cherry
From: cherry@GENOME.STANFORD.EDU (Mike Cherry)
Newsgroups: bionet.software.acedb
Subject: Re: Suitable configuration for ACEDB/WCS?
Date: 17 Feb 1994 23:13:03 -0000
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 17
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> We have been asked what hardware is needed to run the ACEDB system
> and the WCS. In particular the latter, which prequisites are there in 
> terms of OS, memory, disk usage? We have some workstations here running 
> SGI's IRIX and DEC's Ultrix and OSF/1. Please mail me and I'll summarize 
> if there is enough interest. 

I believe WCS is only available for SPARCs. They do not give out
source.  There has also not been an update for two years from the
Arizona WCS group. However, I believe Bruce Schatz has now moved to
the University of Illinois at least that is what I remember from the
hype in Science from last August. The last e-mail address I had was
wcs@cs.arizona.edu. I would like to learn if WCS is still alive.

To answer your question for a SPARC  we run wcs on a IPC with 24Mb RAM,
and it requires 34Mb of disk space.

Mike

From owner-acedb@net.bio.net Thu Feb 17 22:00:00 1994
Path: biosci!BADLANDS.NODAK.EDU!jweiland
From: jweiland@BADLANDS.NODAK.EDU (John J Weiland)
Newsgroups: bionet.software.acedb
Subject: Whereabouts of Colin M. Thacker
Date: 18 Feb 1994 14:11:43 -0000
Organization: BIOSCI International Newsgroups for Molecular Biology
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Does anyone know of the current address (Email or otherwise) of Colin M. 
Thacker?  He was last heard of working in worms in British Columbia.  
Thanks! 

			John Weiland
			jweiland@badlands.nodak.edu

From owner-acedb@net.bio.net Mon Feb 21 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!agate!dog.ee.lbl.gov!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: Getting aware of new AceDB files?
Date: 22 Feb 1994 19:03:52 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 48
Message-ID: <2kdkuo$24t@overload.lbl.gov>
References: <2jtdt8$kj7@rc1.vub.ac.be> <EDDY.94Feb22152511@eddy.gen.cam.ac.uk>
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In article <EDDY.94Feb22152511@eddy.gen.cam.ac.uk> eddy@eddy.gen.cam.ac.uk (Edward Welbourne (Genetics)) writes:

>This sounds like something that could go into the FAQ posting; it has a section
>on the ACeDB `family' with an entry per database.  If maintainers of databases
>sent the FAQ maintainer a note to be included in their entry, just saying
>Last major update to software: 1993/Nov/5
>Last major update to data: 1994/Feb/14
>possibly with an extra line for significant minor updates.  This could go 
>with all the other info about the database, which would be a good place for it.
>
>Does that seem a good solution ?


Exactly!  Curators of ACEDB databases are encouraged to design
their own paragraphs in the FAQ, and to send in updates.  If
you have a presence on the World-Wide Web be sure to include
URL's.

Updated FAQ's are posted to this conference around the second
week of each month.  Here is part of the introduction for the
FAQ, which tells you how to get a copy:
    [...]
    This document will be posted monthly to the BIOSCI newsgroup
    bionet.software.acedb and to USENET conference news.answers.
    It is intended to be used as an index to ACEDB databases and
    to information about the database software.
 
    The latest version of the ACEDB FAQ should be available via
    anonymous ftp at machine net.bio.net (134.172.2.69) as
    file pub/BIOSCI/ACEDB/ACEDB.FAQ or at rtfm.mit.edu
    (18.70.0.209) as pub/usenet.news.answers/acedb-faq. Answer 3
    demonstrates a sample FTP session.  If you only have
    electronic mail, the FAQ can be retrieved from
    mail-server@rtfm.mit.edu.

    There is an HyperText Markup Language (HTML) version of this
    document available on the World Wide Web:
        http://probe.nalusda.gov:8000/plant/acedbfaq.html
    [...]


    --bks

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Mon Feb 21 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!s.u-tokyo!news.tisn.ad.jp!news.u-tokyo.ac.jp!sinetnews!daffy!uwvax!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!pipex!warwick!lyra.csx.cam.ac.uk!pavo.csi.cam.ac.uk!nntp-serv.cam.ac.uk!eddy
From: eddy@eddy.gen.cam.ac.uk (Edward Welbourne (Genetics))
Subject: Re: Getting aware of new AceDB files?
In-Reply-To: rherzog@rc1.vub.ac.be's message of 16 Feb 1994 15:25:28 GMT
Message-ID: <EDDY.94Feb22152511@eddy.gen.cam.ac.uk>
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Date: Tue, 22 Feb 1994 15:25:11 GMT
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In article <2jtdt8$kj7@rc1.vub.ac.be> rherzog@rc1.vub.ac.be (Herzog Robert (DBM)) writes:

> Is there any possibility to systematically use this list to post announcement 
> of available updates about ACeDB formatted biological databases?

This sounds like something that could go into the FAQ posting; it has a section
on the ACeDB `family' with an entry per database.  If maintainers of databases
sent the FAQ maintainer a note to be included in their entry, just saying
Last major update to software: 1993/Nov/5
Last major update to data: 1994/Feb/14
possibly with an extra line for significant minor updates.  This could go 
with all the other info about the database, which would be a good place for it.

Does that seem a good solution ?

	Eddy.
--
				...   Few indeed are those who, travelling
it, have crossed the dark and yawning Abyss of Implementation to Delivery.
Many, yea, many in truth stagnate yet in the Desert of Delay, or linger ever
in the ghastly limbo called Perpetual Beta.	(from the LOGINATAKA)

From owner-acedb@net.bio.net Tue Feb 22 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!sol.ctr.columbia.edu!news.kei.com!newsstand.cit.cornell.edu!cornell!uw-beaver!netnews.nwnet.net!ns1.nodak.edu!plains!mcclean
From: mcclean@plains.NoDak.edu (Phillip McClean)
Subject: Otto Ritter E-mail address
Sender: usenet@ns1.nodak.edu (Usenet login)
Message-ID: <CLnD90.MnC@ns1.nodak.edu>
Date: Tue, 22 Feb 1994 22:31:48 GMT
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X-Newsreader: TIN [version 1.2 PL2]
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 I would like to contact Otto Ritter.  The e-mail address that I have is
o.ritter@dkfz-heidelberg.de but it bounces back.  Does anyone have Otto's
current address

Phil McClean
mcclean@plains.nodak.edu

From owner-acedb@net.bio.net Tue Feb 22 22:00:00 1994
Newsgroups: bionet.software.acedb
Path: biosci!daresbury!doc.ic.ac.uk!agate!howland.reston.ans.net!sol.ctr.columbia.edu!news.kei.com!newsstand.cit.cornell.edu!cornell!uw-beaver!netnews.nwnet.net!ns1.nodak.edu!plains!mcclean
From: mcclean@plains.NoDak.edu (Phillip McClean)
Subject: Graphical Pedigrees for ACeDB
Sender: usenet@ns1.nodak.edu (Usenet login)
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 Is anyone working on code for ACeDB that will permit the graphical
display of a given pedigree?  I have a graduate student who might
be interested in such a project, but we do not want to duplicate any
existing efforts.  Contact me by e-mail or post here.  Either will
work fine.

Phil McClean
mcclean@plains.nodak.edu

From owner-acedb@net.bio.net Wed Feb 23 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!agate!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: ACEDB on NeXT?
Date: 24 Feb 1994 22:25:38 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 10
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Message-ID: <2kj9h2$ok@overload.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov


Anyone out there actively porting ACEDB to NeXT machines?

    --bks

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Wed Feb 23 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: semerz@lmcp.jussieu.fr (Michel Semertzidis)
Newsgroups: bionet.software.acedb
Subject: OMEGA_2 data bank announcement
Date: 24 Feb 1994 10:13:39 -0000
Lines: 78
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2khukj$hvg@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk,
 bio-info@dl.ac.uk,
 bio-soft@dl.ac.uk,
 bionews@dl.ac.uk




OMEGA_2 data bank for Mac is now at the
genome.inserm-vjf.fr (192.134.32.20) /pub/OMEGA.
Log in as `anonymous' and enter your email address as your password.

OMEGA_2 data bank is a compilation of recent structural information on proteins.

OMEGA_2 data bank was compiled by
Michel T. SEMERTZIDIS*, Sylvia DEPLANQUE and Jean-Paul MORNON
Département des Macromolécules Biologiques,
Laboratoire de Minéralogie - Cristallographie,
Université Pierre et Marie Curie (Paris 6) et
Denis Diderot (Paris 7), CNRS URA 09, Tour 16,
4 place Jussieu, CASE 115, F-75252 Paris Cedex 05, FRANCE
E-mail: "semerz@lmcp.jussieu.fr"
*To whom correspondence should be addressed

     Suggested citations for use of this data bank are:
Michel T. SEMERTZIDIS, Sylvia DEPLANQUE and Jean-Paul MORNON (1993)
"OMEGA: A 3D Databank for Protein Structures (a complement to PDB)",
CABIOS 9, 667-670.

     RELEASE 1:  JUNE, 1993:    401 proteins.
     RELEASE 2:  JANUARY, 1994: 537 proteins.

ABSTRACT
OMEGA is a compilation of recent structural information on
proteins derived from X-ray crystallography or NMR and
published in journals referenced by Current Contents.
To date, 401 entries have been included ( 334 X-ray, 28 NMR,
5 NMR + X-ray, 5 electron microscopy, 3 neutron scattering,
2 neutron diffraction,  1 electron microscopy + X-ray,
12 model, 11 miscellaneous ), with 5-10 new proteins being
added each week.
OMEGA can be accessed on Macintosh and is interrogated
through 32 key words (space group, resolution, secondary
structure, number of residues, etc). This pool of proteins
could be used for various purposes, including searches for
proteins with a particular set of secondary structures.
OMEGA will be continuously updated (every 6 months) and
may later include all proteins already reported in the PDB,
as well as structures reported in journals with smaller
readerships.

We would greatly appreciate any ideas for improving future
releases. We also apologize in advance for any errors or
omissions that may appear in the database, and would be
grateful to be informed of any errors.
We also welcome submission for entry in OMEGA of any new
publication related to the determination of a protein
structure, as well as the citing of this paper as a
reference for the OMEGA databank.
We would appreciate receiving reprints of publications
making use of OMEGA.

ACKNOWLEDGEMENTS:
This work was supported by the Universités Paris 6 and
Paris 7, CNRS, INSERM (contrats 889009 et 910912),
and Fondation pour la Recherche Médicale.
M.T.S. has a Ph.D. grant from the French government (MRE).


!!! The first time you will use omega it will take some time
for special 4D decompression !!!



TTGATTGCTAAACACTGGGCGGCGAATCAGGGTTGGGATCTGAACAAAGACGGTCAGATTCAGTTCGTACTGCTG
    MICHEL T. SEMERTZIDIS       Internet: SEMERZ@LMCP.JUSSIEU.FR
    University of  Paris 6        Bitnet:
    CNRS URA 09, CASE 115          Phone:
    Tour 16, 4 place Jussieu,        Fax:
    75252 Paris Cedex 05,       System managers do it with PRIVILEGES!
    F R A N C E   
    DISCLAIMER:As always,I speak only for myself,and,usually,only to myself.
LeuIleAlaLysHisTrpAlaAlaAsnGlnGlyTrpAspLeuAsnLysAspGlyGlnIleGlnPheValLeuLeu

From owner-acedb@net.bio.net Wed Feb 23 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!not-for-mail
From: martin@bsm.biochemistry.ucl.ac.uk (Andrew Martin)
Newsgroups: bionet.software.acedb
Subject: Re: Otto Ritter E-mail address
Date: 23 Feb 1994 18:11:57 -0600
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NNTP-Posting-Host: cs.utexas.edu

In article <CLnD90.MnC@ns1.nodak.edu>, mcclean@plains.NoDak.edu (Phillip McClean) writes:
|>  I would like to contact Otto Ritter.  The e-mail address that I have is
|> o.ritter@dkfz-heidelberg.de but it bounces back.  Does anyone have Otto's
|> current address
|> 
|> Phil McClean
|> mcclean@plains.nodak.edu

Otto's address is:
  dok261@cvx12.dkfz-heidelberg.de

o.ritter may well work as an alias for dok261.


Andrew

-- 
****************************************************************************
Dr. Andrew C.R. Martin,         University College London & SciTech Software
INTERNET: martin@bsm.bioc.ucl.ac.uk     -OR-     amartin@scitec.adsp.sub.org
JANET:    martin@uk.ac.ucl.bioc.bsm
UUCP:     {uunet|rutgers}!cbmehq!cbmuk!scitec!amartin
****************************************************************************

