From owner-acedb@net.bio.net Sat Mar 05 22:00:00 1994
Path: biosci!bloom-beacon.mit.edu!gatech!swrinde!cs.utexas.edu!news.tamu.edu!128.194.15.2!leland
From: leland@straylight.tamu.edu (Leland Ellis)
Newsgroups: bionet.software.acedb
Subject: AGsDB, A Genus species DataBase
Date: 06 Mar 1994 03:27:25 GMT
Organization: W.M. Keck Center for Genome Informatics, Institute of Biosciences
	and Technology, Texas A&M University, Houston
Lines: 94
Distribution: world
Message-ID: <LELAND.94Mar5212725@straylight.tamu.edu>
NNTP-Posting-Host: straylight.tamu.edu


			      WWW-AGsDB

	      WWW-ACeDB Server for "A Genus species DataBase"

			   available on the

			      WWW Server

				of the

       W.M. Keck Center for Genome Informatics at the Institute
		      Biosciences and Technology
			 Texas A&M University
			       Houston

		  URL: http://keck.tamu.edu/ibt.html

WWW-AGsDB is a WWW interface to the data contained in AGsDB-1.0, which is
implemented in ACeDB-3.0, the latest (and still beta) version of Richard
Durbin and Jean Thierry-Mieg's ACeDB.  AGsDB is a prototype for a
multi-species database, with datatypes useful in the study of species
of agricultural and biomedical interest, as well as model organisms.
The interface utilizes the ACeDB Server software (nph-acedb3) developed
by Guy Decoux (decoux@moulon.inra.fr), and modified versions of the
models and tags of the human C21 database of Otto Ritter and co.  The
modifications provide for queries between interacting Loci, and between
species via Homologs.

Data from several species can be found in AGsDB:  filamentous fungi
(Aspergillus nidulans, Neurospora crassa), cows (with the corresponding
anchor loci for humans) and cotton (examples as demo).  Recently, we have
begun to enter data for the Cell Cycle, which brings in Homlogs between
Aspergillus and both budding (C. cerevisiae) and fission (S. pombe)
yeast.

The WWW-AGsDB server should be regarded as an experimental prototype.
We do find it useful, but the data models are still being experimented
with, and new data is always being added.  Finally, the db is nowhere
near comprehensive in the data included, but is illustrative of the
datatypes that we routinely use in the study of these organisms.

Futher development of both of the previously announced WWW-DataBases,
WWW-AAnDB (for Aspergillus nidulans) and WWW-ABtDB (for cows), is now
being continued in AGsDB (WWW-AAnDB and WWW-ABtDB have been phased out,
but the data therein is now in AGsDB).

The WWW-AGsDB server is accessible via the WWW Server of Keck-IBT.
This URL

http://keck.tamu.edu/ibt.html

will take you to the Keck-IBT HomePage -- clicking on the Keck-IBT
logo takes you to our 1st page of information, which has a link to
AGsDB.

Any feedback is very welcome at:

leland@straylight.tamu.edu

or

jkirk@keck.tamu.edu

AGsDB is the work of Leland Ellis, Jeff Kirk, Chris Floyd and Janis Bender
at Keck-IBT, with advice on Aspergillus from Tom Adams (Texas A&M) and Greg
May (Baylor College of Medicine), Neurospora from Dan Ebbole (Texas A&M),
cows from Jim Womack (Texas A&M), cotton from Russ Kohel (Texas A&M) and
the Cell Cycle from Greg May (Baylor College of Medicine).

----------------------------------------------------------------------------

Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL: http://keck.tamu.edu/ibt.html

----------------------------------------------------------------------------

--
Leland Ellis, Ph.D.
Professor of Biochemistry and Biophysics
Director, W.M. Keck Center for Genome Informatics
Institute of Biosciences and Technology
Texas A&M University
2121 Holcombe
Houston, Texas  77030
email: leland@straylight.tamu.edu
URL:   http://keck.tamu.edu/ibt.html

From owner-acedb@net.bio.net Mon Mar 07 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!sol.ctr.columbia.edu!news.kei.com!yeshua.marcam.com!zip.eecs.umich.edu!umn.edu!msus1.msus.edu!vax1.mankato.msus.edu!vengeance
Newsgroups: bionet.software.acedb
Subject: Omaha Project
Message-ID: <1994Mar8.085329.2385@vax1.mankato.msus.edu>
From: vengeance@vax1.mankato.msus.edu
Date: 8 Mar 94 08:53:29 -0500
Organization: Mankato State University
Lines: 9

   I am trying to build a list of names and E-Mail addresses of
people in the Omaha Nebraska area for a school related project.
   If you live in Omaha or go to school there or know someone
that does and will be around for three months or more, please
reply via E-Mail to Vengeance@vax1.mankato.msus.edu.

Thank you very much!

Ryan Krueger

From owner-acedb@net.bio.net Tue Mar 08 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!vixen.cso.uiuc.edu!sdd.hp.com!ihnp4.ucsd.edu!dog.ee.lbl.gov!overload.lbl.gov!acedbfaq
From: acedbfaq@s27w007.pswfs.gov (ACEDB FAQ Pseudouser)
Newsgroups: bionet.software.acedb,news.answers
Subject: ACEDB Genome Database Software FAQ
Followup-To: bionet.software.acedb
Date: 9 Mar 1994 20:17:37 GMT
Organization: Dendrome, A genome database for forest trees
Lines: 790
Approved: news-answers-request@MIT.Edu
Message-ID: <2llat1$jdr@overload.lbl.gov>
Reply-To: acedbfaq@s27w007.pswfs.gov
NNTP-Posting-Host: s27w007.pswfs.gov
Summary: Frequently Asked Questions about finding and getting
 started with the database system ACEDB.  ACEDB is used
 to collect information regarding the molecular biology
 of the genome.
Archive-name: acedb-faq
Last-modified: 3/9/94
Version: 1.9
Xref: biosci bionet.software.acedb:177 news.answers:13604

----------------------------------------------------------------------
Common Questions and Answers about ACEDB.

    This document will be posted monthly to the BIOSCI newsgroup
    bionet.software.acedb and to USENET conference news.answers.
    It is intended to be used as an index to ACEDB databases and
    to information about the database software.

    The latest version of the ACEDB FAQ should be available via
    anonymous ftp at machine net.bio.net (134.172.2.69) as
    file pub/BIOSCI/ACEDB/ACEDB.FAQ or at rtfm.mit.edu
    (18.70.0.209) as pub/usenet.news.answers/acedb-faq. Answer 3
    demonstrates a sample FTP session.  If you only have
    electronic mail, the FAQ can be retrieved from
    mail-server@rtfm.mit.edu.

    There is an HyperText Markup Language (HTML) version of this
    document available on the World Wide Web:
        http://probe.nalusda.gov:8000/plant/acedbfaq.html
    [Until I get more familiar with HTML, it may not be totally
     synchronized with the plain FAQ. --bks]

    Curators of ACEDB databases should take note of Question 4 and
    keep me apprised of changes.

    Errors of commission or omission are unintentional.  If I have
    forgotten to give you credit please let me know.  Please
    send comments and corrections to: acedbfaq@s27w007.pswfs.gov
        --Bradley K. Sherman 

----------------------------------------------------------------------
The List of questions in the ACEDB FAQ.  Questions marked with
+ are new, those with ! have substantially changed answers:

Q0:  What is ACEDB?
Q1:  What is the current version of ACEDB?
Q2:  !What hardware|software do I need to run ACEDB?
Q3:  Where can I get ACEDB?
Q4:  !What ACEDB databases exist?
Q5:  What written documentation exists for ACEDB?
Q6:  Where can I find further information about ACEDB?
Q7:  How should ACEDB be cited?
Q8:  Is ACEDB object-oriented?
Q9:  What's all this about Gopher|WAIS|Anonymous ftp|WWW|URL ...
Q10: How can I get on the ACEDB announcements mailing list?
Q11: When and where is the next ACEDB Workshop?
Q411:Who contributed to this document?

----------------------------------------------------------------------
Q0:  What is ACEDB?

A0:  ACEDB is an acronym for A Caenorhabditis elegans Database.  It can
     refer to a database and data concerning the nematode C. elegans,
     or to the database software alone.  This document is concerned
     primarily with the latter meaning.  ACEDB is being adapted by many
     groups to organize molecular biology data about the genomes of
     diverse species [see Q4].

     ACEDB allows for automatic cross-referencing of items during
     loading and allows for hypertextual navigation of the links
     using a graphical user interface and mouse.  Certain special
     purpose graphical displays have been integrated into the
     software.  These reflect the needs of molecular biologists
     in constructing genetic and physical maps of genomes.

     ACEDB was written and developed by Richard Durbin (MRC LMB
     Cambridge, England) and Jean Thierry-Mieg (CNRS, Montpellier,
     France), beginning circa 1990.  It is written in the C programming
     language and uses the X11 windowing system to provide a platform
     independent graphical user interface.  The source code is publicly
     available [See Q3].  Durbin & Thierry-Mieg continue to develop
     the system, with contributions from other groups including
     Lawrence Berkeley Laboratory and the European integrated Genome
     Project.

     A description by Durbin & Thierry-Mieg:
         ACEDB does not use an underlying relational database
         schema, but a system we wrote ourselves in which data
         are stored in objects that belong in classes.  This is
         nevertheless a general database management system using
         caches, session control, and a powerful query language.
         Typical objects are clones, genes, alleles, papers,
         sequences, etc.  Each object is stored as a tree,
         following a hierarchical structure for the class (called
         the "model").  Maps are derived from data stored in tree
         objects, but precomputed and stored as tables for
         efficiency.  The system of models allows flexibility
         and efficiency of storage -missing data are not stored.
         A major advantage is that the models can be extended
         and refined without invalidating an existing database.
         Comments can be added to any node of an object.
         Current display modes are:
             TREE   for text type objects: papers, authors, genes
             etc.
             GMAP   genetic map
             PMAP   physical map (Sulston contig style)
             SEQ    DNA sequence - symbolic, features, sequence
             and translation
             GRID   hybridisation patterns for a probe to a clone
             grid
             BIBLIO bibliography attached to any object display
             modules under development:
             CMAP   whole chromosome physical map plot
             GEL    agarose gel simulation derived from sequence

----------------------------------------------------------------------
Q1:  What is the current version of ACEDB?

A1:  As of January 1994, ACEDB has undergone a bifurcation.  Those
     involved with C. elegans will want to to track the 2.x series
     under the stewardship of Richard Durbin and all other groups
     should probably track the 3.x series of Jean Thierry-Mieg.
     Thierry-Mieg writes "... 2 and 3 differ only at the level of
     displays ..."  Version 2.0 was released in December, 1993 and
     version 3.0 was released in January, 1994.
 
     To retrieve the software see Q3.

     To be kept informed of new releases see Q10.

     [This question refers to the software not the C. elegans data.]

----------------------------------------------------------------------
Q2:  What hardware/software do I need to run ACEDB?

A2:  ACEDB currently runs on the following Unix systems, under X11:
     Unix:
         o Any machine running SunOS 4.x
         o SPARCstation 10 under Solaris [Probably all Solaris, then --bks]
         o DEC  DECstation3100, 5100 etc.
         o DEC  Alpha/OSF-1
         o Silicon Graphics Iris series
         o PC 386/486 with Linux (free Unix)
         o There exist, or have existed, ports onto Alliant, Hewlett-
           Packard, IBM R6000, Convex.   You may have to contact
           the developer responsible for the port to make these real.
         o NeXT: contact Patrick Phillips at University of Texas,
           NeXTmail: patrick@wbar.uta.edu
           phil@decster.uta.edu
    MSDOS/Windows/NT:
        A port to NT is rumored to be in the works.
    Macintosh:
        A port to the Macintosh may become available real soon now.
        Beta versions of this *might* be found at the ACE archives.
        See Q3.  Here is a note from Richard Durbin:
           There is now a tested Macintosh version.
           You need a Macintosh with >16Mb of memory
           and a decent monitor.  You also need some
           way of obtaining the files from an ftp site
           (e.g. NCSA telnet, Versaterm Pro...) and
           Stuffit Deluxe, which I am told costs $65
           in the USA, and is useful anyway for
           compressing/decompressing files.  It turns
           out >that Stuffit Deluxe can decompress Unix
           .tar.Z archive files.  Frank Eeckman has now
           made available a .tar.Z archive of a complete
           C. elegans ACEDB database, with updates already
           read in.  Ftp to genome.lbl.gov, folder
           pub/macace, and follow the instructions in
           README.  Thank you Frank.

    For cost savings, a combination of a high-end Intel platform
    with Linux appears very attractive.

    Here at the Institute of Forest Genetics we run ACEDB on a 
    Sun Microsystems SPARCstation II, and users can interact
    using Macintoshes and PC-clones by using X11 implementations
    for the personal computers and a LAN.  [This section should
    be expanded to have a more thorough discussion of X11
    interactions.  --bks]

----------------------------------------------------------------------
Q3:  Where can I get ACEDB?

A3:  All the files are available in the following public access
     accounts (anonymous ftp sites) accessible via Internet:
        lirmm.lirmm.fr (193.49.104.10) in pub/acedb
        cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb
        ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb
        bioinformatics.weizmann.ac.il (132.76.55.12) in
            pub/databases/acedb.

    A typical session would be:
        ftp ncbi.nlm.nih.gov
        login: anonymous
        password: your email address
        cd repository/acedb/ace3
        binary
        ls
        get README_3
        get NOTES
        get INSTALL
        get bin.sparc.3.0.tar.Z
        quit

----------------------------------------------------------------------
Q4:  What ACEDB databases exist?

A4:  [In alphabetic order by Database name --bks]

     Database : AAnDB-1.0
     Species : Aspergillus nidulans
     PI : Leland Ellis
     Last_update : February 1994
     ACEDB_version : 3.0
     Contact : leland@stralight.tamu.edu
     URL : http://keck.tamu.edu/ibt.html
     Comment : defunct, See AGsDB

     Database : AAtDB
     Species : Arabidopsis thaliana
     Availability : 
     Curator : John Morris
     Current version: 1-5
     Contact : curator@frodo.mgh.harvard.edu
     Last_update : Sept. 1993

     Database : ABtDB-1.0
     Species : Bovine, Bos taurus
     ACEDB_version : 3.0 extended
     PI : Leland Ellis
     Last_update : February 1994
     Contact : leland@stralight.tamu.edu
     URL : http://keck.tamu.edu/ibt.html
     Comment : defunct, See AGsDB

     Database : ACeDB
     Species : Caenorhabditis elegans
     Current version: 2-9
     Curator : Jean Thierry-Mieg
     Curator : Richard Durbin
     Contact : rd@mrc-lmb.cam.ac.uk
     Contact : mieg@kaa.crbm.cnrs-mop.fr
     Last_update : March 1994

     Database : AceMap
     Species : Homo Sapiens (Saccaromyces Pombe, Mus musculus in development)
     Focus : Physical mapping of human chromosomes X and 21
     Curator : Hugues Roest Crollius
     Contact : hrc@gea.lif.icnet.uk
     PI : Hans Lehrach
     PI : Hugues Roest Crollius
     Last_update : 22 Feb 1994

     Database : AGhDB
     Species : Gossipium hirsutum (cotton)
     PI : Leland Ellis
     Curator : Stephanie Crouch
     Last_update : March 1994
     Contact : leland@stralight.tamu.edu
     URL : http://keck.tamu.edu/ibt.html

     Database : AGsDB  A Genus species Database
     Species : Aspergillus nidulans
     Species : Neurospora crassa
     Species : cow w/ human anchor loci
     Species : cotton (demo)
     Species : Homologs of Aspergillus cell cycle loci
               for budding and fission yeast
     Contact : Leland Ellis (leland@straylight.tamu.edu)
     Based_on : ACeDB-3.0 (beta still), with extensions to the Human
                C21 Models to provide for multiple species, and queries
                between species via Homologs (e.g., cell cycle loci with
                links via Homologs between Aspergillus and budding 
                C. cerevisiae) and fission (S. pombe) yeast);
                interacting loci via defined Interactions for each locus
     Models : as of 3.6.94
     Data : as of 3.6.94
     Revision :  AAnDB for Aspergillus nidulans and ABtDB forBos taurus
                 (cow) have been folded into AGsDB, and are not being
                 developed futher as individual species databases
     WWW : WWW-AGsDB is an interface of AGsDB with the World-Wide Web,
           and utilizes the WWW-ACeDB Server (nph-acedb3) of Guy Ducoux
           (ducoux@moulon.inra.fr).
     URL : http://keck.tamu.edu/ibt.html

     Database : ASbDB
     Species : Sorghum bicolor
     PI : Leland Ellis
     Curator : Stephanie Crouch
     Last_update : March 1994
     Contact : leland@stralight.tamu.edu
     URL : http://keck.tamu.edu/ibt.html

     Database : ChlamyDB
     Species : Chlamydomonas
     PI : Elizabeth Harris
     Contact : chlamy@acpub.duke.edu
     Availability : Still under construction
     Last_update : 30 Sept. 1993

     Database : EcoDB
     Species : E. coli
     PI : Staffan Bergh
     Contact : staffan@biochem.kth.se
     Availability : Still under construction
     Last_update : 11 Oct. 1993

     Database : FlyBase
     Species : Drosophila melanogaster
     Availability : gopher or gopher+ ftp.bio.indiana.edu
     Availability : ACeDB-style interface to SyBase server
                    due by end of 1994
     Curator : Edward Welbourne
     Contact : eddy@gen.cam.ac.uk
     Contact : flybase@morgan.harvard.edu
     PI : William Gelbart
     PI : Michael Ashburner
     PI : Thomas Kaufman
     PI : Kathy Matthews
     PI : John Merriam

     Database : Flydb
     Species : Drosophila melanogaster
     Availability : by request only, via ftp
     Curator : Suzanna E. Lewis
     Contact : SELewis@lbl.gov
     Focus : STS content mapping project summary
     PI : Gerald Rubin
     PI : Mike Palazzolo
     PI : Dan Hartl
     PI : Alan Spradling
     Last_update : Sept. 1993

     Database : GrainGenes
     Species : Wheat, barley, oats, relatives
     Availability : Gopher greengenes.cit.cornell.edu port 70
     Availability : ACEDB version by ftp, on request from the curators
     Curator : David E. Matthews
     PI : Olin D. Anderson
     Contact : matthews@greengenes.cit.cornell.edu
     Contact : oandersn@wheat.usda.gov
     URL : gopher://greengenes.cit.cornell.edu/1/
     Data_version : 1.3
     Released : 12 Jan 1994
     Based_on : acedb.1-10
     Availability : See following WWW URL
     URL :  http://probe.nalusda.gov:8000/acedbs/acedbs/graingenes/index.html
     Last_update : Feb. 1994

     Database : human.c17
     Species : Homo sapiens
     Availability :  the database is under development
     Contact : lsprilus@weizmann.weizmann.ac.il
     Focus :  mapping & sequencing of Human Chromosome 17
     Based_on: acedb.3-0
     Last_update : Jan. 1994

     Database : Mace
     Species : Zea mays L. ssp. mays
     Focus : Maize genome
     Comment : Mace is the front end for maizedb, a relational
               (SYBASE) database. It is updated from maizedb by
               software written by Stan Letovsky.  Maizedb is
               updated daily and will soon be accessible by
               public login.
     Curator : Ed Coe 
     Curator : Pat Byrne
     Curator : Georgia Davis
     Curator : Mary Polacco
     Off-Site Curator : Marty Sachs 
     Off-Site Curator : Christiane Fauron 
     Off-Site Curator : Carolyn Wetzel
     Off-Site Curator : Steve Rodermel 
     Off-Site Curator/Designer : Stan Letovsky 
     Off-Site Curator/Designer : Mary Berlyn 
     Systems Manager : Denis Hancock
     PI : Ed Coe
     Contact : maizedb@teosinte.agron.missouri.edu
     Last_update: 5 October 1993

     Database : MycDB
     Species : Mycobacterium
     PI : Staffan Bergh
     PI : Thierry Garnier
     Contact : staffan@pasteur.fr
     Last_update : Sept. 1993

     Database : RiceGenes
     Species : Rice (O. sative)
     Availability : under development, login at own risk
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SolGenes
     Coverage: Solanaceae - tomato, potato, pepper (eventually)
     Availability : Beta ACEDB via login or tar file
     Curator : Edie Paul
     Contact : epaul@nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SoyBase
     Species : Soybeans
     Curator :  Lisa Lorenzen
     PI : Randy Shoemaker
     Contact : lorenzen@mendel.agron.iastate.edu
     Last_update : Sept. 1993

     Database : TreeGenes
     Species : Forest trees
     Availability : alpha, contact curator
     ACEDB_version : 1-10
     Curator : Bradley K. Sherman
     PI : David B. Neale
     Contact : Dendrome@s27w007.pswfs.gov
     Contact : bks@s27w007.pswfs.gov
     Contact : dbn@s27w007.pswfs.gov
     Last_update : March 1994
     URL : gopher://s27w007.pswfs.gov/
     URL : http://s27w007.pswfs.gov/
     URL : ftp://probe.nalusda.gov/pub/trees

     Database : 21Bdb
     Species : Homo sapiens
     Availability : by request, via ftp, gopher
     Curator : Donn F. Davy
     Contact : DFDavy@lbl.gov
     Contact : aggarwal@genome.lbl.gov
     Focus : STS content mapping & sequencing of Human Chromosome 21
     PI : Jasper Rine
     PI : Michael Palazzolo
     PI : Chris Martin
     PI : Jan-Fang Cheng
     Last_update : Sept. 1993

     Database : VoxPop
     Species : Populus spp.
     Availability : contact curator
     Curator : Carl G. Riches
     PI : Reinhard F. Stettler
     Contact : cgr@poplar1.cfr.washington.edu
     Contact : STETTLER@coyote.cfr.washington.edu
     Last_update : Sept. 1993

     Database : ?
     Species : Sorghum
     PI : Leland Ellis
     Last_update : Sept. 1993

     Database : ?
     PI : Scott Chasalow
     Species : Potato
     Contact : Scottish Crop Institute, Dundee
     Last_update : Sept. 1993

     Database : ?
     PI : George Murphy
     PI : David Flanders
     Species : Arabidopsis thaliana
     Contact : John Innes Center, Norwich, England
     Last_update : Sept. 1993

     Database : ?
     Species : Homo sapiens
     Focus : Physical mapping of human chromosomes 22 and X
     Curator : Ian Dunham
     Contact : idunham@crc.ac.uk id1@sanger.ac.uk
     PI : Ian Dunham
     PI : David Bentley
     Last_update : 28 Sep 1993

     [Curators:  Please submit an entire paragraph in
      this format for inclusion or update. --bks]


----------------------------------------------------------------------
Q5:  What written documentation exists for ACEDB?

A5:  The primary documents are included in the Software
     distribution in the wdoc subdirectory:
         acedb -- A C. elegans Database: I. Users' Guide.
         acedb -- A C. elegans Database: II. Installation Guide.
         acedb -- A C. elegans Database: III. Configuration Guide.
         Syntactic Definitions for the ACEDB Data Base Manager
             --Jean Thierry-Mieg and Richard Durbin (1991-)
     You will find other interesting documents in the wdoc subdirectory.

     By anonymous ftp from ncbi.nlm.nih.gov (130.14.20.1)
     in repository/acedb:
        doc.1_9.tar.Z

     Cherry, J.M., Cartinhour, S.W., and Goodman, H.M. (1992) AAtDB,
     An Arabidopsis thaliana Database. Plant Molecular Biology Reporter
     10 (4): 308-309,409-410

     Tutorial manual for AAtDB:
     Cartinhour, S., Cherry, J.M., and Goodman, H.M. (1992) An
     Introduction to ACeDB: For AAtDB, An Arabidopsis thaliana
     Database. Massachusetts General Hospital. (Available on
     request in printed form from the AAtDB curator).

     A description of ACEDB:
     Cherry, J.M. and Cartinhour, S.W. (1993) ACEDB, A tool for
     biological information. in Automated DNA Sequencing and
     Analysis, edited by M.  Adams, C. Fields, and C. Venter.
     Academic Press (in press).  [text is available through
     ftp or gopher from weeds.mgh.harvard.edu]

     Another description of ACEDB for physical mapping projects:
     Dunham, I., Durbin, R., Mieg, J-T & Bentley, D.R. (1993)
     Physical mapping projects and ACEDB, in Guide to Human
     Genome Computing. Ed.  Bishop, M.J.  (Academic Press)
     (review, in press).  [text is available through ftp or
     gopher from weeds.mgh.harvard.edu]

----------------------------------------------------------------------
Q6:  Where can I find further information about ACEDB?

A6:  There is a Usenet/Biosci conference titled bionet.software.acedb.
     If you do not have access to the Biosci conferences via a
     newsreader (e.g. rn, trn) you can participate in the conference
     by electronic mail.  To subscribe to the e-mail version of the
     conference send email to biosci-server@net.bio.net (UK, European
     readers use biosci@uk.ac.daresbury or biosci.daresbury.ac.uk) with
     no subject line and only the message
           subscribe ACEDB-SOFT
     in the body.  To unsubscribe send the message
           unsubscribe ACEDB-SOFT
     to the same address.
     This is an automated service.  Your e-mail address will be taken
     from the header of the message that you send.  If you then send
     mail to acedb@net.bio.net the mail will be distributed to all
     subscribers and to the electronic conference.

     Mike Cherry has set up an ACEDB Developer's archive.  For
     anonymous ftp use the hostname weeds.mgh.harvard.edu and look in
     the acedb_dev directory. If you wish to contribute you can put
     files in the incoming directory.  Send a message to Mike
     (cherry@genome.stanford.edu) that you have put something in that
     directory then Mike will move it out for general access.
     For gopher you can connect to weeds.mgh.harvard.edu
     (132.183.190.21) and ...
        -->  N.  FTP Archives for Molecular Biology/
     then
        -->  M.  ACEDB Developer's archive/
     [N and M are integers which are subject to change.]

     The bionet.software. acedb.conference is archived and can be
     searched using WAIS.  Here is a Gopher-style link to the WAIS
     archive. (This is also courtesy of Mike Cherry.):
          #
          Type=7
          Name=ACEDB BioSci Electronic Conference
          Path=7/.index/acedb-biosci
          Host=genome-gopher.stanford.edu
          Port=70

     The AAtDB, Soybase, GrainGenes, Mace, and TreeGenes (see Q4)
     databases regularly submit data to the Plant Genome Database
     at the National Agricultural Library (NAL).  Nal makes this
     data available via the WWW using an http server with URL:
         http://probe.nalusda.gov:8000/index.html
     You will also find a selection of models.wrm files (schemata)
     for the various databases here.  You will want to get a
     "mosaic client" to examine this.

     Other URL's that readers with mosaic clients might want to
     examine are:
        http://moulon.inra.fr/acedb/acedb.html for C. elegans data
        http://moulon.inra.fr/acedb/mycdb.html for Mycobacterium data
        http://moulon.inra.fr:8001/acedb/igd.html for an integrated
            genome database.
     For information on how these were created see
        http://moulon.inra.fr/acedb_conf_eng.html
        http://moulon.inra.fr/acedb_conf.html (en francais)

     The Genome Computing Group, Lawrence Berkeley Laboratory
     has an anonymous ftp service at machine genome.lbl.gov
     (131.243.224.80) which contains:
          flydb - LBL's Drosophila Acedb-style database
          21bdb - LBL's Human Chromosome 21 Acedb-style database
          querdb - LBL's query-language extensions to Acedb 
          metadata - LBL's compendium of Acedb database schema variants
          macace-aatdb-demo.hqx  -  pre-release Acedb MacIntosh version
          There is also a repository of contributed software for
          data conversions and the like.

     Computer staff for the UC Berkeley Drosophila physical mapping
     project the LBL Human Chromosome 21 project, and the LBL plant
     genome projects meet regularly to coordinate their ACEDB
     extension and development efforts, along with Frank Eeckman,
     who is working on the Macintosh version of ACEDB (for further
     information, contact jlmccarthy@lbl.gov). They also keep in
     close touch (via email, personal visits, etc.) with their
     counterparts in Cambridge (Richard Durbin et al), Montpellier 
     Jean Thierry-Mieg et al), and the Interated Genome Database
     project in Heidelburg (Otto Ritter, Detlef Wolf et al).

----------------------------------------------------------------------
Q7:  How should ACEDB be cited?

A7:  From the distribution:

        We realize that we have not yet published any "real" paper on
        ACEDB.  We consider however that anonymous ftp servers are a
        form of publication. We would appreciate if users of ACEDB
        could quote:
            Richard Durbin and Jean Thierry Mieg (1991-). A C. elegans
            Database.  Documentation, code and data available from
            anonymous FTP servers at lirmm.lirmm.fr,
            cele.mrc-lmb.cam.ac.uk and  ncbi.nlm.nih.gov.

        Papers involved in database development could quote more
        precisely:
           I.   Users' Guide. Included as part of the ACEDB distribution
         kit,
           II.  Installation Guide. Included as part of the ACEDB
         distribution
           III. Configuration Guide. Included as part of the ACEDB
         distribution

        and the preprintkit, available by Anonymous FTP from ...
           Jean Thierry-Mieg and Richard Durbin (1992). Syntactic
           Definitions for the ACEDB Data Base Manager. Included as
           part of the ACEDB distribution.

             --Jean and Richard.

----------------------------------------------------------------------
Q8: Is ACEDB object-oriented?

A8: From the ACEDB User's Guide.

    A major current vogue in computer languages and database design
    is for ``object-oriented'' systems.  It's also a source of lots
    of argument.  We are just trying to build a good system, and
    don't want to get caught in the crossfire, but we do talk about
    organising our data into objects and classes.  We have undoubtedly
    been influenced by many of the ideas going around, but it isn't
    likely our system would be regarded as kosher by the object-
    oriented community.  In particular there is no class hierarchy, nor
    inheritance, and it is written in a modular but non-ideological way
    in straight C. However display and disk storage methods are class
    dependent.

    In some ways the class hierarchy is replaced by our system of
    models and trees, which seems to be rather unusual.  We think it
    is very natural for the representation of biological information,
    where for some members of a class a lot might be known about some
    aspect, but for most only a little is known.

    The advantages of our sytem over a relational database, such as
    Oracle or Sybase, is our ability to refine our descriptions without
    rebuilding the database and the possibility of organising the
    storage of data on disk according to their class, i.e. we store in
    a very different way the tree-objects and the long stretches of
    DNA sequence.

----------------------------------------------------------------------
Q9:  What's all this about Gopher/WAIS/Anonymous ftp/WWW ...

A9:  These terms all refer to Internet protocols.
     An excellent introduction to the Internet is:
       _The Whole Internet User's Guide & Catalog_,
       by Ed Krol, O'Reilly & Associates, 1992.
     Or ask your system administrator to provide you with
     a gopher client or mosaic client and begin navigating
     on your own. 

     URL is a Universal Resource Locator on the World-Wide
     Web (WWW).  There are many free Internet browsers
     available that allow you to use an Internet connection
     and a URL to access services.  Mosaic may be the
     most popular and it is available for Mac, PC or Unix
     via anonymous ftp from ftp.ncsa.uiuc.edu.

----------------------------------------------------------------------
Q10: How can I get on the ACEDB announcements mailing list?

A10: To get on or off the mailing list send mail to
     rd@mrc-lmb.cam.ac.uk or mieg@kaa.crbm.cnrs-mop.fr.
     New releases of the software are announced to
     this list.

----------------------------------------------------------------------
Q11: When and where is the Next ACEDB Workshop?

Q11: From Jean Thierry-Mieg:
     DATES:
     The acedb '94 workshop will be held july 2 to 16, in Saint Matthieu
     de Treviers, a small village, 20 km north of Montpellier, at the
     foot of the Pic Saint Loup.

     HOUSING:
     We have booked a place meant for family vacations which includes
     ample space, a nice conference room and ten studios meant for 5
     people (bathroom, shower, kitchenette, terrace, all nice and clean)
     that we plan to share among 3 to 4 participants.  Meals will be
     taken at a local restaurant.

     The place is ideal for work and informal discussions and will be
     well equiped with computers. The situation is nice for hiking and
     allows volley-ball, ping-pong, tennis and petanque.

     We can provide lists of possible hotels for those who would prefer
     more privacy or find ways of accomodating families if you let us
     know very soon (school ends early july in France).

     Cost for 2 weeks is 1000 FF (about 200 US dollars) for housing on
     site plus 2500 FF for full meals. We may get enough funding to
     reduce this cost, but cannot pay for travel.

     PROGRAM:
     Formal presentations and general discussions will take place in the
     mornings and the evenings, alternating network aspects, data handling,
     displays and genome data analaysis.

     The afternoons will be dedicated to data manipulation, programming
     and writing documentation. The idea is to actually implement during
     the meeting many of the ideas that will come up, to fuse and
     coallesce the now numerous acedb-based applications into a working
     modular package, and to import and consolidate large sets of
     additional data.

     Towards this goal, we will broadcast the following announcement

     ACEDB'94 Genome Database Workshop.

     Montpellier, July 2-16, 1994

     This meeting will cover the use and development of the 
     ACEDB database manager central to several major genome projects,
     including C.elegans, A.thaliana, human, and a number of
     other plant and animal species. 

     We wish to encourage people with large sets of data on other
     organisms to attend this workshop. They will be helped to build,
     during the meeting, a friendly graphic presentation of their own
     data, in return for discussing their own experience.

     *******************************************************************

     FORMAT:
     This meeting will be much longer than the 2 previous acedb workshops
     (Cambridge 92 and Boston 93), in the hope of initiating new
     collaborations and allowing concrete results. This format is usual in
     physics summer schools and often very productive.
     
     The workshop may be coupled to a 2 days presentation of acedb, open
     to the general audience, and yet to be organised.
     
     We anticipate at least the participation of people from: Berkeley,
     Boston, Cambridge, Heidelberg and Montpellier, including Richard
     Durbin (LMB and Sanger Centre, Cambridge), John McCarthy (LBL,
     Berkeley), Otto Ritter (DKFZ, Heidelberg), Danielle and Jean
     Thierry-Mieg (CNRS, Montpellier).

     Please confirm your participation and forward this announcement to
     your colleagues.

     Danielle and Jean Thierry-Mieg 
     CNRS-CRBM
     BP 5051,
     34033  Montpellier, France.

     email mieg@kaa.crbm.cnrs-mop.fr
      (if this address fails, fall back on mieg@ncbi.nlm.nih.gov)

     Tel: (33) 67 61 33 24
     Fax: (33) 67 52 15 59

----------------------------------------------------------------------
Q411:Who contributed to this document?
     [Note to international readers: 411 is the phone number for
     information in the USA. --bks]

A411: Major contributions in getting this FAQ off the ground
      were made by John McCarthy and Mike Cherry.  Other
      contributors include:
        Lisa Lorenzen
        David Matthews
        Edie Paul
        Donn Davy
        Eric De Mund
        Sam Cartinhour

      To add or modify information in this document, please
      send mail to: acedbfaq@s27w007.pswfs.gov

      Bradley K. Sherman
      Dendrome Project                
      Institute of Forest Genetics    
      P.O. Box 245, Berkeley, CA, 94701
      Phone: 510-559-6437 Fax: 510-559-6440  

      The Dendrome Project and TreeGenes are funded by the
      Office of the Plant Genome, USDA ARS.

---------------------End of file acedb-faq----------------------------

From owner-acedb@net.bio.net Sun Mar 20 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!vixen.cso.uiuc.edu!newsrelay.iastate.edu!news.iastate.edu!lfevold
From: lfevold@iastate.edu (Linda J Fevold)
Newsgroups: bionet.software.acedb
Subject: Any information about Acedb
Date: 21 Mar 1994 18:56:14 GMT
Organization: Iowa State University, Ames, IA
Lines: 3
Distribution: usa
Message-ID: <2mkqke$p5v@news.iastate.edu>
NNTP-Posting-Host: bus1.iastate.edu

-- 
Linda Fevold
lfevold@iastate.edu

From owner-acedb@net.bio.net Sun Mar 20 22:00:00 1994
Path: biosci!MIRANDA.UMDS.AC.UK!fsymons
From: fsymons@MIRANDA.UMDS.AC.UK (Fernley Symons)
Newsgroups: bionet.software.acedb
Subject: (none)
Date: 21 Mar 1994 11:52:35 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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Message-ID: <1842.9403211940@miranda.umds.ac.uk>
NNTP-Posting-Host: net.bio.net

unsubscribe

From owner-acedb@net.bio.net Mon Mar 21 22:00:00 1994
Path: biosci!daresbury!trane.uninett.no!eunet.no!EU.net!howland.reston.ans.net!agate!dog.ee.lbl.gov!overload.lbl.gov!slavsing.lbl.gov!user
From: jlmccarthy@lbl.gov (John L. McCarthy)
Newsgroups: bionet.software.acedb
Subject: Proposed Extensions for ACEDB Query Builder
Followup-To: bionet.software.acedb
Date: 22 Mar 1994 19:22:37 GMT
Organization: Lawrence Berkeley Laboratory
Lines: 210
Message-ID: <jlmccarthy-220394113110@slavsing.lbl.gov>
NNTP-Posting-Host: slavsing.lbl.gov

Proposed Extensions for ACEDB Query Builder

We'd like your suggestions on proposed Query Builder extensions to make it
clearer and permit certain types of queries it currently does not do:

I. "Follow" to another class via a tag in the current class; and

II. "Next" where there are multiple data fields with a single tag.


REVIEW OF CURRENT QUERY BUILDER INTERFACE

The current query builder has boxes to  fill in as shown below.  
Here pipes and underscores are used to simulate boxes, % to indicate an
editable area selectable by mouse, and @ to represent downward pointing
triangles which can be clicked to bring up a list window for permissible
values that can be mouse selected for entry in that particular box.  (you
must display this in a monospace font to line up things correctly in their
respective boxes).

Query Builder:(Click right mouse button on the shaded boxes for choices)
                +---------------+
Find and select |%%%%%%%%%%%%% @| items
                +---------------+
       +----------------+ +----------+ +--------+ +-----------+
 where |%%%%%%%%%%%%%% @| |%%%%%%%% @| |%%%%%% @| |%%%%%%%%% @|
       +----------------+ +----------+ +--------+ +-----------+

The first box is used to specify class, while the four on the next line are
used to specify tag, operator, value and conjunction, respectively.

Values displayed in the list for <TAG> are determined
by the CLASS selected on the first line.

If a conjunction other than the default "END" is specified, Query Builder
automatically creates another "where" line to be filled in.
There can be as many additional where lines as the user wishes.


PROPOSED REVISIONS

We propose to revise the current Query Builder as follows:

A. change wording of first line to indicate triangles for choices;

B. delete "and select" before first box and add "class" after it;

C. add type of information below each box to help user understanding;

D. in conjunctions list, substitute default "to get keyset." for END;

E. add "and next field" to the conjunctions list;

F. add "and follow" at the end of the conjunctions list;

G. use different wording under tag box for "next" and "follow".


The net result would look something like as follows:

Query Builder:   (click triangle in any box for choices)
     +-------------------------+
Find |%%%%%%%%%%%%%%%%%%%%%%% @| class items
     +-------------------------+
       +----------------+ +----------+ +--------+ +-----------+
 where |%%%%%%%%%%%%%% @| |%%%%%%%% @| |%%%%%% @| |%%%%%%%%% @|
       +----------------+ +----------+ +--------+ +-----------+
        <tag>              <operator>   <value>   <conjunction>

(A) proposes to drop pop-up menus as an alternate mechanism for getting
lists of allowable values.  There is a limitation of the widget currently
being used for popup menus that prevents scrolling beyond the top or bottom
of the window; so users cannot get at the bottom of very long lists.  Until
this shortcoming is overcome, it seems best to have a single mechanism --
namely the triangles that bring up separately scrollable windows (which
must be dismissed before proceeding).

(B) is a relatively minor change in wording to clarify what is being done. 
[Suggestions for improvement welcome!]
The first (default) item on the class list would be changed to "ANY".

(C) is intended to help clarify what goes in what box, and to differentiate
what happens in lines after "and next field" or "and follow class" (see
below).

(D,E,F) The expanded list of conjunctions is proposed as follows:
   to get keyset.
   and
   or
   exclusive or
   and next field
   and follow class

1. The first list change is the simple default that terminates a query.
The proposal is to change it from "END" to " "to get keyset."  
Although "END" is shorter, it is less intuitive. 

2. The second change is to add a choice "and next field," the result of
which would be to bring up an additional "where" line in which the user
could specify some constraint on the second data field following the tag
(and which would get translated into a "next" ACEDB query phrase). In this
case, the label under the first box would change to "<data field> and the
choices available for that box would be limited to the data fields
following the first one in the model (indicated by putting the data type
following the tag in that box -- e.g., "Float").

3. The third conjunction list change is to add "and follow class."  If a
user chooses "and follow class", the Query Builder will automatically
create another "where" line to be filled in, as it does for other
conjunctions like "and" or "or."  In this case, however, the label under
the first box would change to "<tag ?Class>.  The list that appears if the
user clicks the triangle in that TAG box is a subset of those tags in the
current class whose values are names of other ?Classes.  The default
operator would remain "exists" (as in the original line). 

Users can further restrict such "Follow" queries by filling in other
operators and values to restrict the values of connected class objects thus
chosen, or by choosing another conjunction and going on to another line in
which they can specify restrictions on any tag in the connected class
specified by the tag in the line following "and follow class."
They can also go on to a third connected class by specifying another "and
follow class" in the conjunction box.


EXAMPLES

A simple query might look like this (CAPS FOR VALUES FILLED IN):

Find PAPER class items
 where YEAR     >        1990    to get keyset.
       <tag> <operator> <value>  <conjunction>

A query on a tag that had multiple fields might look like this:
Find Locus class items
 where gMap    exists             and next field
       <tag> <operator> <value> <conjunction>
 where FLOAT            >        12      and
       <data field> <operator> <value> <conjunction>
 where FLOAT           <          20     to get keyset
       <data field> <operator> <value> <conjunction>

NOTE: evaluation remains on same data field if "and" is conjunction.

An indirect (Follow) query might look as follows:

Find GENE items
 where ITEM NAME      CONTAINS   ADH    and follow class
       <tag>        <operator> <value> <conjunction>
 where CLONE ?Clone   EXISTS            and follow class
      <tag ?Class>  <operator> <value> <conjunction>
 where SEQUENCE ?Sequence  EXISTS             and
      <tag ?Class>        <operator> <value> <conjunction>
 where DNA            CONTAINS  AATTGG  to get keyset
      <tag>         <operator> <value> <conjunction>


I hope this example is more understandable (and legal) than my last one.
The idea here is that we (1) find genes that contain the string ADH; (2)
proceed to find any clones (a different class) connected to those genes
where the clones have sequence information; and (3) get a keyset of clones
from those where the DNA sequence contains the substring AATTGG.  [Jean: is
this ok?]

Note that follow can occur after multiple specification of constraints and
could even lead back through a class that was used for other purposes
earlier in a prior line of the query. 


"SMART" DEFAULTS

David Matthews has suggested that we consider inserting other default
values in the initial Query Builder boxes, depending on context.  

Currently, QB can only be invoked from the main window, and it comes up
with "ANY CLASS" in the class box, "ANY TAG" in the tag box, and "contains"
in the operator box.  One alternative would be to put the name of the class
of the currently selected class (top left default) in the first box.  If we
knew other information (from another window? e.g., tree text display), we
could put the currently selected tag in the box after "where" on the next
line and could even fill in the other boxes with "equals", and "<value>" if
a data field is selected.  I'm not sure how easy it is to get such
information from a window other than the currently active (main) window. 
Another alternative might be to make the Query Builder invokable from the
Tree Display, but that would add to the length of that already long menu.


DISCUSSION

The logic of our basic proposal seems OK, and the ACEDB query language
already supports it. The problem is that the wording may not be
sufficiently clear to help new users understand what is happening.

Adding explanatory text below the boxes does add clutter and uses up more
vertical real estate, but my hope is that it may help clarify what is going
on -- especially for "and next field" and "and follow class."

I would very much appreciate any advice about how we might better clarify
things via further changes in wording, layout, or whatever.

We would also appreciate comments & suggestions about "Smart Defaults."

-- 

+=====================================================================+
|  John L. McCarthy.               . | Internet:..JLMcCarthy@lbl.gov  |
|  Computer Science R&D  MS 50B-3238 | Bitnet: ...JLMCCARTHY@LBL      |
|  Lawrence Berkeley Laboratory     .| telephone: (510) 486-5307      |
|  1 Cyclotron Road                . |                                |
|  BERKELEY, CA 94720, U.S.A.      . | FAX:       (510) 486-4004      |
+=====================================================================+

From owner-acedb@net.bio.net Mon Mar 21 22:00:00 1994
Path: biosci!UX5.LBL.GOV!suzi
From: suzi@UX5.LBL.GOV (Suzanna Lewis)
Newsgroups: bionet.software.acedb
Subject: Re: ACEDB mailing lists
Date: 22 Mar 1994 13:23:54 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 20
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403222124.AA10931@ux5.lbl.gov>
NNTP-Posting-Host: net.bio.net


----- Begin Included Message -----

What's the symptom?  Is this why when I doubleclick too fast the window
system locks up (ignores all mouse and keyboard input, though the clock and
perfmeter keep running) and I have to kill xace, and about half the time have
to kill the window system too?  I never tried "Mouse pointer to focus".

- Dave

----- End Included Message -----


Yes thats exactly what we were seeing.  The non-fix "fix" is to go to the
openlook Properties window for the Miscellaneous category and there you'll
find an option for "Set Input Area".  The default is "Click SELECT".  What
works for acedb is "Move Pointer".  Just apply this change and a lot of the
ace lockups will dissapear.

Suzanna

From owner-acedb@net.bio.net Mon Mar 21 22:00:00 1994
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: Re: ACEDB mailing lists
Date: 22 Mar 1994 12:45:50 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 20
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403222049.AA03267@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

> From suzi@ux5.lbl.gov Tue Mar 22 15:27:47 1994
> To: acedev@genome.lbl.gov, cherry@genome.stanford.edu
> Subject: Re: ACEDB mailing lists
> ...
> 
> By the way, another one of those little pesky bugs.  I may again
> be the last to know, but here goes.  If you are using openlook
> make sure to change the default focusing scheme.  "Click to focus"
> doesn't work, it must be "Mouse pointer to focus".  Otherwise ace
> can get confused about which window has the focus and think that
> none of the windows do.
> 
> Suzanna

What's the symptom?  Is this why when I doubleclick too fast the window
system locks up (ignores all mouse and keyboard input, though the clock and
perfmeter keep running) and I have to kill xace, and about half the time have
to kill the window system too?  I never tried "Mouse pointer to focus".

- Dave

From owner-acedb@net.bio.net Mon Mar 21 22:00:00 1994
Path: biosci!daresbury!trane.uninett.no!sunic!pipex!howland.reston.ans.net!agate!agate!hcobb
From: hcobb@fly2.berkeley.edu (Henry J. Cobb)
Newsgroups: bionet.software.acedb
Subject: Lockup bug under Olwm.
Date: 22 Mar 1994 21:37:03 GMT
Organization: University of California, Berkeley
Lines: 16
Message-ID: <HCOBB.94Mar22133703@fly2.berkeley.edu>
References: <9403222049.AA03267@greengenes.cit.cornell.edu>
NNTP-Posting-Host: fly2.berkeley.edu
In-reply-to: matthews@GREENGENES.CIT.CORNELL.EDU's message of 22 Mar 1994 12:45:50 -0800


	Yes, click to focus under Olwm will get Xace and the WM to not talk
to each other anymore.

	The funny part about all of this is that the Programmers had all
changed to "focus follows mouse" while the Biologists had never even heard
of this.  So they always got bit by the bug and it never bothered us.

	I've been tasked with fixing up the X widgets, handling WM_PROTOCOL
and etc., but I first need a complete style guide for Ace widgets.  With
that in hand I'll be able to test to make sure that each does exactly what
is intended.

--
	Henry J. Cobb hcobb@fly2.berkeley.edu, SFB Tyrant-for-life
"yes, I also suspect that RMS is a MITI agent too." -- Piercarlo Grandi

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!dkfz-heidelberg.de!D.Wolf
From: D.Wolf@dkfz-heidelberg.de (Detlef Wolf)
Newsgroups: bionet.software.acedb
Subject: a test - please ignore
Date: 23 Mar 1994 06:21:22 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 1
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199403231421.AA02777@cvx12.inet.dkfz-heidelberg.de>
NNTP-Posting-Host: net.bio.net

Detlef

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!agate!library.ucla.edu!europa.eng.gtefsd.com!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: extending
Date: 23 Mar 1994 09:31:14 -0000
Lines: 1
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2mp292$p1i@mserv1.dl.ac.uk>
Original-To: net@dl.ac.uk

i agree to post here rather than to acedev

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!agate!howland.reston.ans.net!pipex!sunic!trane.uninett.no!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: Re:  Lockup bug under Olwm.
Date: 23 Mar 1994 09:03:35 -0000
Lines: 8
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2mp0l7$nqt@mserv1.dl.ac.uk>
Original-To: hcobb@fly2.berkeley.edu

the complete guide style for ace widget is that the user should not
be bothered by silly bugs,

this point/click to focus should not create a hang
it is obviously part of the platform dependant code so should be
fixed in xtsubs i guess, anyway totally outside of the
mainstream ace code.


From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Date: 22 Mar 1994 23:43:47 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 25
Message-ID: <2mnvrj$2o6@overload.lbl.gov>
References: <jlmccarthy-220394113110@slavsing.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov

In article <jlmccarthy-220394113110@slavsing.lbl.gov> jlmccarthy@lbl.gov (John L. McCarthy) writes:
>Proposed Extensions for ACEDB Query Builder

So as not to appear ignorant, I thought that I would find the latest
documentation on using the query language & the query builder. After
about an hour I located a tar file in france  that contains some
PostScript files that expect A4 paper and some .tex files.  I tried
using the LaTex and dvips that I have access to, but the programs
complained loudly and I gave up.

So, I will run the risk of appearing ignorant:
  Where is the latest documentation on using the Query Language?
  Where is the latest documentation on using the Query Builder?
  Are there lots of nice examples?
  How do I print them here in the states?

    --bks

p.s. Will add this to FAQ.

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!VECTOR.NALUSDA.GOV!scartinh
From: scartinh@VECTOR.NALUSDA.GOV (Sam Cartinhour)
Newsgroups: bionet.software.acedb
Subject: ACEDB documentation
Date: 23 Mar 1994 05:46:05 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 24
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403231344.AA17830@vector.nalusda.gov>
NNTP-Posting-Host: net.bio.net


Hi,

Brad Sherman recently asked

>  Where is the latest documentation on using the Query Language?
>  Where is the latest documentation on using the Query Builder?
>  Are there lots of nice examples?
>  How do I print them here in the states?

I am working on an ACEDB documentation server for www and am hoping it
may help with these questions. It is intended to be a repository for
the most recent ace documentation available. I would like to present
ace information of all sorts, contributed by developers and curators,
and solicit new as well as existing documentation. Topics will range
from user manuals, manuals on how to configure acedb, code documentation
for developers, descriptions of specific features, etc etc.

I will of course need help!!

I am not quite ready to open the server up for public inspection; it
still needs some grooming. I think in a week or so perhaps....

sam

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!usc!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: xv/ACEDB display on PC's
Date: 23 Mar 1994 21:31:59 -0000
Lines: 49
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2mqcgf$4e@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk


This message I just received looks relevant to the newsgroup:

Date: Wed, 23 Mar 94 12:57:21 EST
From: Russell Malmberg <russell@dogwood.botany.uga.edu>
Message-Id: <9403231757.AA13867@dogwood.botany.uga.edu>
To: rd@mrc-lmb.cam.ac.uk
Subject: Acedb, xv, 256 colors
Status: R

This is something that I ran across, and I thought it
might interest you since Acedb uses xv as an image
viewer.
Recently I've started using an Xwindows package to
connect from my DOS-MS-Windows PC to the UNIX server
on which the database is installed, (aatdb in this case).
I had problems viewing color images on my pc using the
xv program, either directly or through Acdb-aatdb.
I discussed this with the company that made my Xwin package
(MicroXwin from starnet, demo version on internet as
 "xwindemo")
They maintain that there is a problem with xv and more than
256 colors over this kind of linkage.  They sent me a FAQ
that indicated it was something about depth 24 and 32 bits
per pixel - I didn't understand it.

So, I can get nice images this way if I configure my video
driver and monitor to 256 colors, instead of my standard
65,000 colors.

This might happen more in the future since:
-- there are more people with PC-Xwindows pacages.
-- currently available Windows-DOS systems come
   standard with powerful video drivers that
   are built for 65,000 or 16.7 million colors.
   These are easily re-configurable to 256 colors,
   by clicking a button and re-starting windows.

So:  If someone writes you and indicates more or less that
  they are getting a blank window for an image, or one with
   weird fuzzy lines -- and they are using an Xwindows to
   PC program -- you might advise them to switch to 256 colors.

I'm not an expert on any of this.  Its just what's happened
to me so far in trying to use this snazzy linkage to f run
Acedb -- aatdb.

Russell Malmberg
russell@dogwood.botany.uga.edu

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: xv 2.21 for Solaris?
Date: 23 Mar 1994 09:15:59 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 3
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403231719.AA04344@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

Does anybody have a copy of xv 2.21 that runs on Solaris 2.X?
Thanks,
- Dave

From owner-acedb@net.bio.net Tue Mar 22 22:00:00 1994
Path: biosci!mii.lu.lv!mahinovs
From: mahinovs@mii.lu.lv (Jurijs Mahinovs)
Newsgroups: bionet.software.acedb
Subject: help
Date: 23 Mar 1994 08:32:44 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 1
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199403231627.AA03208@circenis.mii.lu.lv>
NNTP-Posting-Host: net.bio.net

help

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!GENOME.STANFORD.EDU!cherry
From: cherry@GENOME.STANFORD.EDU (Mike Cherry)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Date: 24 Mar 1994 10:17:26 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 35
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199403241818.KAA20661@aeffle.Stanford.EDU>
References: <2msjav$m90@overload.lbl.gov>
NNTP-Posting-Host: net.bio.net

> >                          ...  There is a file called doc.tar.Z
> >which exists on all four servers:
> > lirmm.lirmm.fr (193.49.104.10) in pub/acedb/ace2
> > cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb/ace2
> > ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb/ace2
> > bioinformatics.weizmann.ac.il (132.76.55.12) in pub/databases/acedb/ace2
> 
> 
> In this there are 4 PostScript files:
>   configuration_guide.ps
>   installation_guide.ps
>   syntax.ps
>   users_guide.ps
> which are very helpful.  I was unable to print these --at first--
> as they are formatted for A4 paper and my HP LaserJet 4M printer
> demanded that I put some in.  So I told it that I had put some
> in (a lie) and it seems to be printing them okay.
> 
> I will add a note about this to the FAQ.  (If anyone wants to
> convert the .tex files to 8.5" x 11" format PostScript and
> make these available via anonymous ftp, I'll add a pointer.)
> 
>     --bks

The TeX and PostScript versions of these files are also on the ACEDB
Developer's Archive, anonymous ftp to weeds.mgh.harvard.edu look in
acedb_doc. The PostScript version print fine on normal US size paper.
With the appropriate TeX software you can produce a copy of these
papers for most any printer.

Also note that in the directory acedb_dev there are many file that
might be of interest to folks configuring ACEDB and utilities to
convert files into Ace format.

Mike

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Date: 24 Mar 1994 18:13:57 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 16
Message-ID: <2msl95$mih@overload.lbl.gov>
References: <2mnvrj$2o6@overload.lbl.gov> <2mqk0e$cfj@overload.lbl.gov> <jlmccarthy-240394080544@slavsing.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov

In article <jlmccarthy-240394080544@slavsing.lbl.gov> jlmccarthy@lbl.gov (John L. McCarthy) writes:
>As Sam Cartinhour has written in another message, the National Agricultural
>Library will very shortly have an experimental WWW server for ACEDB
>documentation, including the Syntax document. 

Excellent!  By the way, there is an HTML version of the
<a href="http://probe.nalusda.gov:8000/plant/acedbfaq.html"> ACEDB-FAQ </a>
available.

    --bks

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!agate!dog.ee.lbl.gov!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Date: 24 Mar 1994 17:40:47 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 32
Message-ID: <2msjav$m90@overload.lbl.gov>
References: <jlmccarthy-220394113110@slavsing.lbl.gov> <2mnvrj$2o6@overload.lbl.gov> <2mqk0e$cfj@overload.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov


Okay.  I was ignorant.  Here's a summary:

>                          ...  There is a file called doc.tar.Z
>which exists on all four servers:
> lirmm.lirmm.fr (193.49.104.10) in pub/acedb/ace2
> cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb/ace2
> ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb/ace2
> bioinformatics.weizmann.ac.il (132.76.55.12) in pub/databases/acedb/ace2


In this there are 4 PostScript files:
  configuration_guide.ps
  installation_guide.ps
  syntax.ps
  users_guide.ps
which are very helpful.  I was unable to print these --at first--
as they are formatted for A4 paper and my HP LaserJet 4M printer
demanded that I put some in.  So I told it that I had put some
in (a lie) and it seems to be printing them okay.

I will add a note about this to the FAQ.  (If anyone wants to
convert the .tex files to 8.5" x 11" format PostScript and
make these available via anonymous ftp, I'll add a pointer.)

    --bks

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!slavsing.lbl.gov!user
From: jlmccarthy@lbl.gov (John L. McCarthy)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Followup-To: bionet.software.acedb
Date: 24 Mar 1994 16:08:43 GMT
Organization: Lawrence Berkeley Laboratory
Lines: 24
Message-ID: <jlmccarthy-240394080544@slavsing.lbl.gov>
References: <jlmccarthy-220394113110@slavsing.lbl.gov> <2mnvrj$2o6@overload.lbl.gov> <2mqk0e$cfj@overload.lbl.gov>
NNTP-Posting-Host: slavsing.lbl.gov

In article <2mqk0e$cfj@overload.lbl.gov>, bks@s27w007.pswfs.gov (Bradley K.
Sherman) wrote that he is unable to print syntax.ps or syntax.tex and asked

"Is there any documentation for the query builder?"

As Sam Cartinhour has written in another message, the National Agricultural
Library will very shortly have an experimental WWW server for ACEDB
documentation, including the Syntax document. 

Documentation for the Query Builder is included as part of ACEDB's Help.
If you are in the Query Builder, simply click on the "Help" button.
This documentation is included as part of the ascii help.wrm file.

This on-line help will be revised when the proposed Query Builder
extensions are implemented.

-- 
+=====================================================================+
|  John L. McCarthy.               . | Internet:..JLMcCarthy@lbl.gov  |
|  Computer Science R&D  MS 50B-3238 | Bitnet: ...JLMCCARTHY@LBL      |
|  Lawrence Berkeley Laboratory     .| telephone: (510) 486-5307      |
|  1 Cyclotron Road                . |                                |
|  BERKELEY, CA 94720, U.S.A.      . | FAX:       (510) 486-4004      |
+=====================================================================+

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!biosci!not-for-mail
From: staffan@biochem.kth.se (Staffan Bergh)
Newsgroups: bionet.software.acedb,bionet.announce
Subject: MycDB release 1-5/3-5
Date: 23 Mar 1994 20:56:26 -0800
Organization: Biochemistry, KTH, Stockholm
Lines: 133
Sender: kristoff@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: world
Message-ID: <2mp4a4$imq@kiev.physchem.kth.se>
NNTP-Posting-Host: net.bio.net
Xref: biosci bionet.software.acedb:194 bionet.announce:1025


MycDB 1-5/3-5

Stockholm & Paris March 18, 1994

The third release of the Mycobacterium database, MycDB, is now
available.

MycDB is funded by the WHO and the Fondation Raoul Follereau and is
maintained jointly by the Unite de Genetique Moleculaire Bacterienne
at the Institut Pasteur in Paris, France and the Departement of
Biochemistry at The Royal Institute of Technology in Stockholm,
Sweden.

MycDB is available free of charge via Internet network transfer. A
complete description of the procedure to retrieve the software and
database is available (see MycDB.Retrieval). If you are impatient, see
the end of this message.

Since last release of data, the database manager software has
undergone some changes. Partly due to this fact and partly for
administrative reasons this release comes in two versions called 1-5
and 3-5, where version 1-5 is configured for ace1 and 3-5 for
ace3. Note that the two versions are NOT compatible with each
other. There are also some changes to the models, requiring a complete
reload of the database. In the future we will only support the ace3
version, so if you already have MycDB set up, consider changing to
ace3 and if you do not have the software installed, do install
ace3. Addresses and instructions are in the file MycDB.Retrieval.

MycDB uses the excellent database software written by Richard Durbin
(MCR-LMB, UK) and Jean Thierry-Mieg (CNRS, France). The ACEDB software
allows the user to browse information by simply pointing and clicking
with the workstation mouse. A variety of powerful query methods are
also available. However, our experience is that most users choose the
mouse interface to find the information they are interested in.

As far as possible all information is connected to other information
in the database. The database software presents the information in
separate windows that allow many parts of the database to be viewed at
one time.  There are also many paths to any piece of information,
allowing the user to easily navigate the connections between the
various types of information.

New in release 1-5/3-5:

   Software version. MycDB now uses ACEDB1-10 (use updates 1-1 to
   1-5) or ACEDB3-0 (use updates 3-1 to 3-5). Note that we will in the
   future only make updates available for version 3 of the software. 

   Model changes. As a consequence of changing software and feedback
   from users the models have changed. This unfortunately means you
   will have to restart the database from scratch. (If you have used the
   database for your own data, contact staffan for further info.) 

   A WorldWideWeb server has been set up (replacing the gopher), and
   can be found at the URL http://kiev.physchem.kth.se/MycDB.html. 

   The M.tuberculosis physcal map has been removed, as we are currently
   working on finishing it. We hope to have this ready by next release. 

   New sequences. Many new sequences from GenBank/EMBL/DDBJ, with
   added annotations and similarity search results. Also sequences from
   Doug Smiths sequencing project at Collaborative Research (Thanx
   Doug). 

   Bibliography and address list has been updated. 

Release 1-2 of MycDB contained:

   MycDB now uses version 1-9 of the ACEDB software with, among
   other improvements, improved query facilities. 

   The cosmid physical map of M.tuberculosis produced at the LGMB.
   (this is a working version, kindly provided by Wolfgang Philipp and
   Sylvie Poulet). 

   A update of the compilation of nucleotide sequences from
   mycobacteria in GenBank and EMBL. 

   An extended list of antigens and antibodies, now including the
   CDC/WHO list of antibodies available to mycobacteriologists. 

   Addresses of more than 60 researchers. 

Release 1-1 of MycDB contained:

   The cosmid physical map of M.leprae produced at the LGMB. 

   A compilation of nucleotide sequences from mycobacteria in GenBank
   and EMBL. 

   A compilation of antigens and antibodies, based on the article of
   Young et al. 

   More than 1200 references downloaded from MedLine. 

The database currently requires a Unix workstation running
X-Windows. A variety of precompiled versions of the ACEDB database
software are available through anonymous ftp. See the file
MycDB.Retrieval for more info.  An (experimental) Macintosh version of
the ACEDB software is also available.

If you wish to obtain the MycDB database please contact us, via
e-mail, fax, mail or telephone. If you are impatient and are already
familiar with internet/ftp, all relevant information can be found at

   The WWW server at the Departement of Biochemistry, KTH: 
       http://kiev.physchem.kth.se/MycDB.html 
   The ftp server at the Departement of Biochemistry, KTH: 
       kiev.physchem.kth.se (130.237.52.64) in pub/MycDB 
   The ftp server at Institut Pasteur: 
       ftp.pasteur.fr (157.99.64.12) in pub/MycDB 

The file MycDB.Retrieval describes in more detail the database system
requirements, network retrieval procedures for obtaining the database
and methods of obtaining future updates.

For more information contact Staffan Bergh or Stewart Cole. 

Staffan Bergh 
Biochemistry,
  Royal Institute of Technology, S-100 44 Stockholm, Sweden 
Email: staffan@biochem.kth.se
Fax: (46 8) 24 54 52
Voice: (46 8) 790 8758

Stewart Cole 
Unite de Genetique Moleculaire Bacterienne,
  Institut Pasteur, F-75724 Paris, Cedex 15, France
Email: stcole@pasteur.fr
Fax: (33 1) 45.68.85.93
Voice: (33 1) 45.68.84.46

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software.acedb
Subject: Re: Proposed Extensions for ACEDB Query Builder
Date: 23 Mar 1994 23:39:58 GMT
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 42
Message-ID: <2mqk0e$cfj@overload.lbl.gov>
References: <jlmccarthy-220394113110@slavsing.lbl.gov> <2mnvrj$2o6@overload.lbl.gov>
NNTP-Posting-Host: s27w007.pswfs.gov

In article <2mnvrj$2o6@overload.lbl.gov> bks@s27w007.pswfs.gov (Bradley K. Sherman) writes:
>
>So as not to appear ignorant, I thought that I would find the latest
>documentation on using the query language & the query builder. After
>about an hour I located a tar file in france  that contains some
>PostScript files that expect A4 paper and some .tex files.  I tried
>using the LaTex and dvips that I have access to, but the programs
>complained loudly and I gave up.


Let me be clearer about this.  There is a file called doc.tar.Z
which exists on all four servers:
 lirmm.lirmm.fr (193.49.104.10) in pub/acedb/ace2
 cele.mrc-lmb.cam.ac.uk (131.111.84.1) in pub/acedb/ace2
 ncbi.nlm.nih.gov (130.14.20.1) in repository/acedb/ace2
 bioinformatics.weizmann.ac.il (132.76.55.12) in pub/databases/acedb/ace2

This file when uncompressed and untar'ed has a variety of
documentation.  The files syntax.ps and syntax.tex document
the query languate.  But I cannot print them!  My HP laserjet
4M printer which seems happy with most standard PostScript
files complains and will not print the .ps files --though it
does print the Postscript output of ACEDB.   I am not a TeX
maven, but I tried to convert the .tex file to PostScript
using LaTex and dvips but could not as both programs gave
error messages.

So, how do I print these files?  Is there any documentation
for the query builder?

    --bks

p.s. I do have hardcopy of the 10 Dec 92 document
"Syntactic Definitions for the ACEDB Data Base Manager"
but I have a feeling that this was given to me as
hardcopy.

-- 
Bradley K. Sherman               P.O. Box 245                    
Computer Scientist               Berkeley, CA, 94701
Dendrome Project                 510-559-6437 FAX: 510-559-6440  
Institute of Forest Genetics     Internet: bks@s27w007.pswfs.gov

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: homology map
Date: 24 Mar 1994 00:22:08 -0000
Lines: 65
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2mqmfg$ki8@mserv1.dl.ac.uk>
Original-To: net@dl.ac.uk

Dear non-worm breeders

I just finised writing for the next ace release (ace.3-1 due soon)
2 modif in the map and multimap display
I want to explain here what i did to get feedback if that is not waht is needed.

1) maps
I added in the Map model a line

Symbol Text UNIQUE Text // class tag
so that if present, in that map, object from class class will show 
with the name of their tag

this can be obtained also if for the class
in the option file you say

-Symbol tag

2) Multimap

the following ace file:

****************************

MultiMap Test
Map I.droso
Map II.fly
Anchor Locus In_Group Group_Member


Locus d1
In_Group p1
Map I.droso Position 1.0

Locus d2
In_Group p2
Map I.droso Position 2.0

Locus d3
In_Group p3
Map I.droso Position 3.0

Locus f1
In_Group p1
Map II.fly Position 1.0

Locus f2
In_Group p2
Map II.fly Position 2.20

Locus f3
In_Group p3
Map II.fly Position  2.9


***************************

will make the mutimap test when clicked to come with
joints between d1-f1,  d2-f2,   d3-f3

the magic tag is the tag Anchor
the other names: Locus In_Group Group_Member are to the choice of the
model designer

On request i can send a prerelease.

From owner-acedb@net.bio.net Wed Mar 23 22:00:00 1994
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: Re:  homology map
Date: 24 Mar 1994 10:50:12 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 24
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403241854.AA06267@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

Hi Jean, your new Symbol and Anchor features look great as far as I 
understand them.  I think the only thing I don't understand is:

> MultiMap Test
> Map I.droso
> Map II.fly
> Anchor Locus In_Group Group_Member
> 
> Locus d1
> In_Group p1
> Map I.droso Position 1.0
> 
> ...
> the magic tag is the tag Anchor
> the other names: Locus In_Group Group_Member are to the choice of the
> model designer

I see how "In_Group" gets used in the Locus record.  What does "Group_Member"
do, and how do we use it?  

Also, "Locus" is magic too, right, to specify that "In_Group" is the tag used
to anchor Locus objects?

- Dave

From owner-acedb@net.bio.net Thu Mar 24 22:00:00 1994
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: user selection of Symbol and Anchor
Date: 25 Mar 1994 11:57:30 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 18
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403251918.AA07701@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

1. It would be nice if there were some way to allow the user to switch back
and forth between two sets of Symbols (object labels used on the Map and
Multimap displays).  E.g. between the gene names used by researchers in each
plant's own research community and the kingdom-wide names assigned by the
Commission on Plant Gene Nomenclature.

More generally, it would be empowering to let the user pick _any_ tag of the
Locus (or other Map object) to use as source of the label.  Wouldn't that be
neat?  Who knows what new information people might be able to spot just by
looking at the values of all the tags arrayed against map position.

2. Also there should be some way for the user to select what tag to use as
the Anchor.  There's no way I'm going to be able to construct all the
interesting multimaps in advance and load them as Multimap data, so the users
are going to have to be able to make these by creating Tablemaker tables or
editing existing ones.

- Dave

From owner-acedb@net.bio.net Thu Mar 24 22:00:00 1994
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: Re:  homology map
Date: 25 Mar 1994 10:38:09 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 17
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9403251842.AA07631@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

> ?Map Contains BAC ?BAC XREF Map
> 
> ?BAC Map ?Map XREF BAC #map_location
>      Bac_Class ?BAC XREF Bac_Bunch
>      Bac_Bunch ?BAC XREF Bac_Class
> 
> ## with ace file:
> 
> Multimap bacMultiMap
> Anchor "BAC" "Bac_Class" "Bac_Bunch"

Okay, I understand what the first two parameters do.  "BAC_Class" is the
tag, of class "BAC", whose value is used to decide which BAC's in adjacent
maps should be linked together on the multimap "bacMultiMap".  What does
"Bac_Bunch" do?

- Dave

From owner-acedb@net.bio.net Thu Mar 24 22:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: homology map
Date: 25 Mar 1994 12:59:27 -0000
Lines: 36
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2mun7f$1si@mserv1.dl.ac.uk>
Original-To: net@dl.ac.uk

Mored etail following a question by Matthews:

I see how "In_Group" gets used in the Locus record.  What does "Group_Member"
do, and how do we use it?  

Also, "Locus" is magic too, right, to specify that "In_Group" is the tag used
to anchor Locus objects?

###
answer:
Locus is the name of the class which uses the In_Group Group_Member
tags
but it is not magic

i could invent now a new sort of clone, the butterfly aerodynamic chromosome or BAC


the i will say

?Map Contains BAC ?BAC XREF Map

?BAC Map ?Map XREF BAC #map_location
     Bac_Class ?BAC XREF Bac_Bunch
     Bac_Bunch ?BAC XREF Bac_Class

## with ace file:

Multimap bacMultiMap
Anchor "BAC" "Bac_Class" "Bac_Bunch"

this will work 
the Bac will be dispalyed in the vertical map and
react as desired in the homology map although the
compiled code has never heard as yet of butterflies.



From owner-acedb@net.bio.net Tue Mar 29 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!swrinde!gatech!concert!hearst.acc.Virginia.EDU!portal.gmu.edu!csi.gmu.edu!mark
From: mark@csi.gmu.edu (Mark)
Newsgroups: bionet.software.acedb
Subject: Russian Biological Database Workshop
Date: 29 Mar 1994 23:31:31 GMT
Organization: George Mason University, Fairfax, Virginia, USA
Lines: 152
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An Informal Workshop

Biological Database Integration

June 8 - June 10, 1994

Pushchino, Russia

We invite friends and colleagues interested in the integration of
biological databases to join us for an informal workshop in Pushchino,
Russia, in late spring.  There are substantial benefits be gained by
successfully integrating existing biological databases. There are
numerous Russian databases that need cross referencing with Western
counter parts. Toward this end, we wish to foster an environment in
which researchers exchange insights, data, and tools. This particular
meeting will focus on topics relating to metabolism, since the new
availability of DBEMP --- with its extensive encoding of the
literature relating to metabolism --- will offer numerous categories
of data that have not been available before.  In addition, we will
invite a number of representatives from the Russian scientific
community to discuss their biological databases. It is, perhaps, worth
noting that the Russian scientific community developed a major
computational infrastructure similar to that which has developed in
Europe, America and Japan.  They created substantial collections of
data ranging from small efforts done by single experts curating a
limited class of data to huge collections on topics like metabolism,
medicinal properties of compounds, 3D structural data, sequence data,
culture collections, and genetic markers. We intend to provide a
framework where the contents of these databases can be discussed
examined, and compared with what is currently available in Europe and
America.

The meeting will be hosted by Evgenii Selkov, the leader of the team
that has developed DBEMP over the past decade (the team now includes
24 individuals).  The registration fee ($550 US), will cover housing
and meals, as well as transportation to and from the Moscow airport
(Pushchino is about 100 kilometers or so south of Moscow). In
addition, each participant will be given a coupon worth $400 towards
a purchase of DBEMP (normally sold at $400 for individuals and $4000
for commercial users). The database includes a detailed encoding of
all of the quantitative data in over 10,000 articles on metabolism
and enzymes. Graphical representations of the pathways described in
DBEMP will also be available. A Prolog version of the pathways will
also be made available, and we should be able to recast it to any
other desired format on machines that will be available at the
workshop.

This meeting will not feature scheduled talks; rather, instead we
envision organizing impromptu discussions on topics of common interest
relating to the goal of integrating Russian biological databases with
other international databases. We anticipate a fair amount of
discussion relating to metabolism and enzymes, but other topics such
as availability and exchange of data relating to phylogeny,
alignments, compounds, motifs, and maps will certainly come up.

We expect to spend about half of the time discussing the contents, use
and how to curate the DBEMP, with its encoding of 10,000 articles on
metabolism and enzymes. Informal presentations on the contents of
this database, on how it can be connected to existing databases, and
how it can be used to address specific computational problems will be
discussed. We plan on offering tables that interrelate records in the
DBEMP with specific enzyme numbers, specific organisms, and specific
metabolic pathways.

The remainder of the meeting will include poster sessions and informal
demos by representatives of other database efforts within the FSU. We
hope to include a number of the larger efforts, including databases
relating to sequence analysis, the study of proteins, human genetics,
medicine, and pharmacology. If you are actively involved in either
the generation or use of integrated biological data, we urge you to
consider joining us.

Workshop supporters:

Chris Beecher 
Anthony Bonner 
Terry Gaasterland 
Pat Gillevet 
Nat Goodman 
Niels Larsen 
Natalia Maltsev 
George Michaels 
Harold Morowitz 
Ross Overbeek 
Evgenii Selkov 
Rick Stevens 
Alexander Zamyatnin

Registration Information

The workshop is limited to 125 participants. To register for this
workshop, complete the registration form and mail with your check made
payable to George Mason University, or credit card authorization to:

Center for Professional Development 
Business Office, Mail Stop 3G3 
George Mason University 
Fairfax, VA 22030-4444

To register by FAX, fill out the form below and send it via FAX to
703/993-2112. Follow up by mailing the original enrollment form with
your payment. Registration fees must be received by May 30, 1994.

For further registration information, please call the Center for
Professional Development at (703)993-2090.



Center for Professional Development

Mail Stop 3G3
Fairfax, Virginia 22030-4444
Workshop Questions can be directed to either 

Ross Overbeek (overbeek@mcs.anl.gov)
George Michaels (gmichael@mason1.gmu.edu) 

***********************************************************************
NOTE: If you would like to use Mosaic to register for this conference,
the URL is: "http://csi.gmu.edu/gsm/ConferenceForm.html"
***********************************************************************


Russian Metabolic Database Conference Registration

   first_name = 
   last_name = 
   e-mail = 
   title = 
   organization = 
   address = 
   city = 
   state = 
   zip = 
   phone = 
   fax = 
   payment_method = CHECK, MASTERCARD, VISA 
   payment_amount = $550 

Credit Card Authorization

Credit Card Number:

Expiration Date: 

Cardholder Name: 

Date: 

Authorizing Signature: 



From owner-acedb@net.bio.net Wed Mar 30 23:00:00 1994
Path: biosci!agate!usenet.ins.cwru.edu!howland.reston.ans.net!pipex!uknet!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: dateType
Date: 31 Mar 1994 09:35:21 +0100
Lines: 15
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <2ne209$er0@mserv1.dl.ac.uk>
Original-To: net@nsfnet-relay.ac.uk


I hope it is useful
To insure better compatibility with OPM and to the request of Dertlef
i introduced a new basic numeric type in acedb
_DateType, to be used like _Int and _Float in models
the whole code nows a bout it.

It is internally a time_t and arithmetics can be
preformed on it in particular the query can find the max min average
off a set of dates, I am not sure if average works well by the way on 
dates.
The input format is the "%c: unix format described in man ctime
sois a string of char but it is internally converted to a time_t number

This is part of the soon to be released ace.3-1

From owner-acedb@net.bio.net Thu Mar 31 23:00:00 1994
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!slavsing.lbl.gov!user
From: jlmccarthy@lbl.gov (John L. McCarthy)
Newsgroups: bionet.software.acedb
Subject: Re: dateType
Followup-To: bionet.software.acedb
Date: 1 Apr 1994 00:10:54 GMT
Organization: Lawrence Berkeley Laboratory
Lines: 39
Distribution: bionet
Message-ID: <jlmccarthy-310394161549@slavsing.lbl.gov>
References: <2ne209$er0@mserv1.dl.ac.uk>
NNTP-Posting-Host: slavsing.lbl.gov

In article <2ne209$er0@mserv1.dl.ac.uk>, mieg@kaa.crbm.cnrs-mop.fr
(Danielle et Jean Thierry-Mieg) wrote:

> 
> I hope it is useful
> To insure better compatibility with OPM and to the request of Dertlef
> i introduced a new basic numeric type in acedb
> _DateType, to be used like _Int and _Float in models
> the whole code nows a bout it.
> 
> It is internally a time_t and arithmetics can be
> preformed on it in particular the query can find the max min average
> off a set of dates, I am not sure if average works well by the way on 
> dates.
> The input format is the "%c: unix format described in man ctime
> sois a string of char but it is internally converted to a time_t number
> 
> This is part of the soon to be released ace.3-1

I think this will be very useful.

As I read man ctime, it says that %c is date and time as %x %X, where 
%x  is date, using locale's date format; and
%X  is time, using locale's time format

e.g, "Thu, 31 Mar 94 02:05:57 PST"

If the format's are locale-dependent, could this cause problems if we
are passing data among different locations in .ace files, and one location
uses different date and time formats from another?  If so, perhaps the
default should be a locale-independent representation.
-- 
+=====================================================================+
|  John L. McCarthy.               . | Internet:..JLMcCarthy@lbl.gov  |
|  Computer Science R&D  MS 50B-3238 | Bitnet: ...JLMCCARTHY@LBL      |
|  Lawrence Berkeley Laboratory     .| telephone: (510) 486-5307      |
|  1 Cyclotron Road                . |                                |
|  BERKELEY, CA 94720, U.S.A.      . | FAX:       (510) 486-4004      |
+=====================================================================+

From owner-acedb@net.bio.net Thu Mar 31 23:00:00 1994
Path: biosci!LBL.GOV!eademund
From: eademund@LBL.GOV (Eric De Mund)
Newsgroups: bionet.software.acedb
Subject: Re: dateType
Date: 31 Mar 1994 17:48:46 -0800
Organization: Lawrence Berkeley Laboratory, Genome Computing Group
Lines: 51
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9404010149.AA06082@csr.lbl.gov>
Reply-To: Eric De Mund <eademund@lbl.gov>
NNTP-Posting-Host: net.bio.net

ACEDBers,

Jean Thierry-Mieg <mieg@kaa.crbm.cnrs-mop.fr>:
] It is internally a time_t and arithmetics can be
] preformed on it in particular the query can find the max min average
] off a set of dates, I am not sure if average works well by the way on 
] dates.
] The input format is the "%c: unix format described in man ctime
] sois a string of char but it is internally converted to a time_t number
] 
] This is part of the soon to be released ace.3-1

John McCarthy <jlmccarthy@lbl.gov>:
] I think this will be very useful.
] 
] As I read man ctime, it says that %c is date and time as %x %X, where 
] %x  is date, using locale's date format; and
] %X  is time, using locale's time format
] 
] e.g, "Thu, 31 Mar 94 02:05:57 PST"
] 
] If the format's are locale-dependent, could this cause problems if we
] are passing data among different locations in .ace files, and one location
] uses different date and time formats from another?  If so, perhaps the
] default should be a locale-independent representation.

The internal representation, time_t, _is_ locale independent. It is the
number of seconds since the epoch, which is defined to be Jan. 1, 1970,
00:00, Greenwich Mean Time.

When producing an ASCII string:

                              ctime(3V)
    integer seconds since ====================> ASCII string
    the epoch

ctime(3V) takes into account the local timezone. The reverse direction:
                              
                          (pack a struct tm, then
                          call) timelocal(3V)

    ASCII string          ====================> integer seconds since
                                                the epoch

takes as input a timezone (or the local timezone if none is specified)
and produces the (locale-independent) number of seconds since the epoch.

Hence it doesn't matter that the displayed representation of the time
is not locale independent.

Eric De Mund <eademund@lbl.gov>

From owner-acedb@net.bio.net Thu Mar 31 23:00:00 1994
Path: biosci!internet!biosci!not-for-mail
From: kristoff (David Kristofferson)
Newsgroups: bionet.software.acedb
Subject: IMPORTANT BIOSCI INFORMATION
Date: 1 Apr 1994 02:00:12 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 244
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199404011000.CAA21649@net.bio.net>
NNTP-Posting-Host: net.bio.net


Three important items follow: BIOSCI archive searching by e-mail, the
BIOSCI FAQ, and the BIOSCI User Address Directory form.  If you have
not yet listed yourself in our e-mail address directory, please take a
few minutes to complete and return the form below.  If your address
information has changed since you listed yourself, please send us an
updated form.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net



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This notice will be mailed bimonthly to each newsgroup.  You should
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		  Using Gopher to complete the form
                  ---------------------------------

If you don't want to use a text editor, you can also use Dan
Jacobson's gopher site to fill out the address database form as
follows.  Otherwise skip this section on gopher and proceed to the
instructions for filling out the form below.

> To add yourself to the database just point your
> gopher client at merlot.gdb.org and select the following:
> 
> -->  15. Searching For Biologists/
> 
>  -->  9.  E-mail Addresses of Biosci-Bionet Users/
> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

> Europeans can point their gopher client at gopher.csc.fi and add their
> information to the database. All entries will be mailed directly to
> Dave for incorporation in a wais source.
> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


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On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIO-SOFTWARE               bionet.software
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

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