From owner-acedb@net.bio.net Sun Oct 01 23:00:00 1995
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: saving Longtexts
Date: 2 Oct 1995 12:51:45 -0700
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Can LongTexts be saved to a file from xace4_1?  This works from tace, but
the Save button in the xace LongText window doesn't do it.
- Dave


From owner-acedb@net.bio.net Tue Oct 03 23:00:00 1995
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: from Jean re: saving Longtexts
Date: 3 Oct 1995 17:05:56 -0700
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I asked:

> Can LongTexts be saved to a file from xace4_1?

Jean had several good suggestions:

> to dump
> select all longtetxs
> from the little triangl next to Class in the main window
> 
> all longtetx then go in the main keyset
> then you ace dump them
> 
> you can always print a window in ascii mode into a file
> 
> ofcourse if youput a name in the yellow box before
> selecting the triangle, you reduce the number of text
> 
> you can also chose an author
> follow papers
> follow abstract from keyset menu
> then ace dump

From owner-acedb@net.bio.net Thu Oct 05 23:00:00 1995
Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.reston.ans.net!tank.news.pipex.net!pipex!news.sprintlink.net!simtel!zombie.ncsc.mil!cs.umd.edu!info.usuhs.mil!hivgenome.hjf.org!user
From: msalminen@hiv.hjf.org (Mika Salminen)
Newsgroups: bionet.software.acedb
Subject: ACEDB database for viruses
Date: Fri, 06 Oct 1995 14:33:17 -0500
Organization: Henry M. Jackson Foundation
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NNTP-Posting-Host: 131.158.31.163

We are thinking of porting a large collection of genbank formatted viral
sequences into an ACEDB based database. We are concerned with trying to
retain as much of the information of the fields in the genbank entries as
possible, and specifically wonder if someone outhere has tools developed
for this purpose already (filters I mean). 

We would especially appreciate advice ofrom someone who might have done
this with another virus, since that would propably be really helpful for
the deign of the database model.


Thanks in avance for your replies,

Mika Salminen

From owner-acedb@net.bio.net Thu Oct 05 23:00:00 1995
Path: biosci!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: security of the ace server
Date: 6 Oct 1995 15:33:56 +0100
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Original-To: net@admcnrs.cnrs-mop.fr

I don t know about the perl client but the security is on the server side and
requires the client to have write/read access on your disk
so that your disk is nsf mounted
unless the database is declared open explicitelly in wspec/server.wrm

so, as far as i see it, only authorised clients local to your machine
running locally will ever be able to talk to the server

the wspec/server.wrm file should belong to acedb user and be 600
so nobody can tamper with it
the server cannot subshell unless setenv ACEDB_SUBSHELL
the server itself (my code) will not edit server.wrm

so i beleive that the server, even ran a s a daemon is secure

From owner-acedb@net.bio.net Thu Oct 05 23:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!elroy.jpl.nasa.gov!lll-winken.llnl.gov!fnnews.fnal.gov!unixhub!news.Stanford.EDU!stout.Stanford.EDU!cherry
From: cherry@stout.Stanford.EDU (Mike Cherry)
Newsgroups: bionet.software.acedb
Subject: Re: ACEDB database for viruses
Date: 6 Oct 1995 21:25:18 GMT
Organization: Stanford University Genetics Department
Lines: 71
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References: <msalminen-0610951433170001@hivgenome.hjf.org>
NNTP-Posting-Host: stout.stanford.edu

In article <msalminen-0610951433170001@hivgenome.hjf.org>,
Mika Salminen <msalminen@hiv.hjf.org> wrote:
>We are thinking of porting a large collection of genbank formatted viral
>sequences into an ACEDB based database. We are concerned with trying to
>retain as much of the information of the fields in the genbank entries as
>possible, and specifically wonder if someone outhere has tools developed
>for this purpose already (filters I mean). 
>
>We would especially appreciate advice ofrom someone who might have done
>this with another virus, since that would propably be really helpful for
>the deign of the database model.
>
>
>Thanks in avance for your replies,
>
>Mika Salminen


I think you will find that any feature used in GenBank/EMBL is
available in ACEDB.  There are a variety of converters available.
Below is a short list as a starting point.

-Mike



All of these converters might be specific to a particular database
project.  That is they will take what they want from GenBank and
discard the rest.

----- My converter -----

Anonymous ftp from weeds.mgh.harvard.edu look in the
/acedb_dev/utilities/gb2ace.sgd.c

There are a few others in that directory too.

----- A recently announced Perl script -----

I don't know how much people want something like this, but...

I've written a Genbank to .ace conversion script in perl.  It handles
the latest version of Genbank flat format files and outputs into ACEDB
version 4 type ?Sequence and ?Paper models.  (The models we use have been
slightly changed from the distribution - a copy is enclosed.)  Most of the
Genbank features are handled, and the user can set an option to generically
handle the features for which I did not write specific code.  The feature
handling routines are in a separate file, so it's easy to extend them.

The tar file is available at:
        http://klab.agsci.colostate.edu/~mferguso/files.html

Enjoy.  Also, please send me your comments (or requests, even).

/s/     Martin Ferguson
        mferguso@klab.agsci.colostate.edu

P.S. If anyone knows of some perl libraries to handle asn.1 data, please
        let me know.


----- GenBank ASN.1 to ACE -----

Hello,
we've written such a beast also, but for the binary representation (ASN.1) as
well as for text files. It is written in C, uses the NCBI toolkit (see
http://www.ncbi.nlm.nih.gov/), and is able to decode Entrez Data with the
help of an additional program. It can be found at

ftp.informatik.uni-stuttgart.de:/pub/DART/ASN2ACE/asn2ace-1.0.tar.gz


From owner-acedb@net.bio.net Tue Oct 10 23:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!tank.news.pipex.net!pipex!dispatch.news.demon.net!demon!sunsite.doc.ic.ac.uk!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: table maker
Date: 11 Oct 1995 18:44:58 +0100
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Distribution: bionet
Message-ID: <45gvqq$eaa@mserv1.dl.ac.uk>
Original-To: matthews@greengenes.cit.cornell.edu


i fixed the text condition

however you can use it already by going in  
obj itself and putting the condiont there

1: Image, condition Pick = "xv"
2: Pick, type Text

whereas
 
1: Image,
2: Pick, type Text, conditon "xv"

does not work in 4.1, will agin in 4.2

From owner-acedb@net.bio.net Wed Oct 11 23:00:00 1995
Path: biosci!dkfz-heidelberg.de!D.Wolf
From: D.Wolf@dkfz-heidelberg.de (Detlef Wolf)
Newsgroups: bionet.software.acedb
Subject: fixed acediffs version
Date: 12 Oct 1995 10:08:55 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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To: acediffs users

thanks to Richard, a bug in acediffs, a fast version of acediff
operating on sorted .ace data, was discoverd and fixed.
the new code is in:

ftp://genome.dkfz-heidelberg.de/igd/people/D.Wolf/acediffs.dist.951012.tar.gz

please discard the pervious version, if you have one.
the bug did not occur often, but is serious (it mixed adjacent objects).

many greetings,
Detlef

-----------------------------------------------------------------------------
Detlef Wolf,   European Data Resource for Human Genome Research
eMail: D.Wolf@dkfz-heidelberg.de  phone: +49 6221 42 -2331   fax: -2333
sMail: DKFZ (German Cancer Research Centre), Abt. Molekulare Biophysik (0810)
       Im Neuenheimer Feld 280,  69120 Heidelberg,  Germany
finger: dok256@genome.dkfz-heidelberg.de
WWW: http://genome.dkfz-heidelberg.de/igd/developers/D.Wolf

From owner-acedb@net.bio.net Wed Oct 11 23:00:00 1995
Path: biosci!ns1.faseb.org!lamarck.sura.net!newsfeed.internetmci.com!elvis.delphi.com!uunet!in2.uu.net!csn!nntp-xfer-2.csn.net!yuma!usenet
From: "Martin L. Ferguson" <martinf@lamar.colostate.edu>
Newsgroups: bionet.software.acedb
Subject: Medline and Genbank conversion updates.
Date: 12 Oct 1995 15:22:21 GMT
Organization: Colorado State University
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X-URL: news:bionet.software.acedb

Hello ACEDB users,

To the 30, or so, of you who have downloaded my perl programs for 
converting Genbank and Medline data into .ace format:  I have recently
placed updates of these on our system.  They can be retrieved from:

	http://klab.agsci.colostate.edu/~mferguso/files.html

Some bugs have been fixed and a few features added.  Also, if you 
download, you will be voluntarily asked to supply your email address.  
If you give it to me, I will mail you notifications of future
updates/bug fixes.

Cheers,  /s/	Martin
-- 
######################################################################
#
#	Martin Ferguson				Dept. of Entomology
#	martinf@lamar.colostate.edu		Colorado State U.
#	970-491-7989				Ft. Collins, CO  80523
#


From owner-acedb@net.bio.net Sun Oct 15 23:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!tank.news.pipex.net!pipex!dispatch.news.demon.net!demon!sunsite.doc.ic.ac.uk!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: parameters in tables in 4.1
Date: 16 Oct 1995 13:00:15 +0100
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Original-To: net@admcnrs.cnrs-mop.fr


I just noticed that in 4.1 parameters
in spread sheets:

// Spread sheet definition for the ACeDB software 
// Date: 1995-10-13_09:04:16

// %n (%%n in the graphic)  are parameter to be given on the command line in tace
// \%n (%n in the graphic) are substituted by the value of column n at run time
// Line starting with // are ignored, starting with # are comments

 do not work, becasu of some indirect effect
 i fixed it, 
 so parameters worked in 3.7, will in 4.2, don't in 4.1
 the reason is that the parameter \%1 in the external file that you load
 is not stripped to %1 in the table that you see on the screen,
 if on the screen, you type %1 (for the value in column 1) the system
 works.
  very sorry

From owner-acedb@net.bio.net Sun Oct 15 23:00:00 1995
Path: biosci!bcm.tmc.edu!cs.utexas.edu!news.sprintlink.net!EU.net!uknet!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: accessing constructed types in table maker
Date: 13 Oct 1995 10:05:31 +0100
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Original-To: net@admcnrs.cnrs-mop.fr


Somebody asked how to do that
since it looks like a general question, here is the way

col 1: Locus

col 2: From 1, Map-?Map

col 3: right_of 2 Position-float

col 4: right of 3 Error-float


the secret is to touch the From button, which then
turns into: Right_of,
then you get in the atg button  the proper model


The exact .def file is:


// Spread sheet definition for the ACeDB software 
// Date: 1995-10-13_09:04:16

// %n (%%n in the graphic)  are parameter to be given on the command line in tace
// \%n (%n in the graphic) are substituted by the value of column n at run time
// Line starting with // are ignored, starting with # are comments

Colonne 1 
Width 12 
Mandatory 
Visible 
Class 
Class Locus 
From 0 
Condition ace*
 
Colonne 2 
Width 12 
Optional 
Visible 
Class 
Class Map 
From 1 
Tag Map 
 
Colonne 3 
Width 12 
Optional 
Visible 
Float 
Right_of 2 
Tag  HERE  # Position 
 
Colonne 4 
Width 12 
Optional 
Visible 
Float 
Right_of 3 
Tag  HERE  # Error 
 
 

// End of these definitions

From owner-acedb@net.bio.net Mon Oct 16 23:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!chi-news.cic.net!simtel!zombie.ncsc.mil!cs.umd.edu!haven.umd.edu!purdue!lerc.nasa.gov!magnus.acs.ohio-state.edu!slip2-16.acs.ohio-state.edu!jesse.5
From: jesse.5@postbox.ohio-state.edu (Jonathan Jesse)
Newsgroups: bionet.software,bionet.software.acedb,bionet.software.gcg
Subject: Using GRASP molecular modeling program.
Date: Tue, 17 Oct 1995 17:06:56 GMT
Organization: The Ohio State University
Lines: 10
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NNTP-Posting-Host: slip2-16.acs.ohio-state.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #4]
Xref: biosci bionet.software:13636 bionet.software.acedb:751 bionet.software.gcg:1418

If anyone out there is familair with "GRASP", what I am trying to do is set up 
a macro that will configure the image in a specific way.  Basically, I have 
many different residues that need to be colored various colors, and it is a 
tedious process typing all of them in at the command line.  If anyone knows 
how to write a macro that can do things like this, I would appreciate the help.

Jon

jesse.5@osu.edu


From owner-acedb@net.bio.net Tue Oct 24 22:00:00 1995
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From: acedbfaq@s27w007.pswfs.gov (ACEDB FAQ Pseudouser)
Newsgroups: bionet.software.acedb,news.answers
Subject: ACEDB Genome Database Software FAQ
Followup-To: bionet.software.acedb
Date: 25 Oct 1995 17:04:15 GMT
Organization: Dendrome, A genome database for forest trees
Lines: 1134
Approved: news-answers-request@MIT.Edu
Message-ID: <46lqmf$g4g@overload.lbl.gov>
Reply-To: acedbfaq@s27w007.pswfs.gov
NNTP-Posting-Host: s27w007.pswfs.gov
Summary: Frequently Asked Questions about finding and getting
 started with the database system ACEDB.  ACEDB is used
 to collect information regarding the molecular biology
 of the genome.
Xref: biosci bionet.software.acedb:752 news.answers:49749

Archive-name: acedb-faq
Last-modified: 10/25/95
Version: 1.25




ACEDB FAQ
*********


Curated by: Bradley K. Sherman 


Frequently Asked Questions about ACEDB
++++++++++++++++++++++++++++++++++++++

 o Q0 : What is ACEDB? 
 o --------------------
 o Q1 : What is the current version of ACEDB? 
 o -------------------------------------------
 o Q2 : What hardware/software do I need to run ACEDB? 
 o ----------------------------------------------------
 o Q3 : Where can I get ACEDB? 
 o ----------------------------
 o Q4 : What ACEDB databases exist? 
 o ---------------------------------
 o Q5 : What documentation exists for ACEDB? 
 o ------------------------------------------
 o Q6 : What other resources are available for ACEDB? 
 o ---------------------------------------------------
 o Q7 : How should ACEDB be cited? 
 o --------------------------------
 o Q8 : Is ACEDB object-oriented? 
 o -------------------------------
 o Q9 : How doe one get on/off the ACEDB announcements mailing list? 
 o ------------------------------------------------------------------
 o Q10 : When and where is the next ACEDB Workshop? 
 o -------------------------------------------------
 o Q11 : Who prepared this document & where is the current version? 
 o -----------------------------------------------------------------

Questions marked with '+' are new, those with '!' have substantially changed
answers. 


Q0: What is ACEDB?
++++++++++++++++++

A0:
+++

ACEDB is an acronym for A Caenorhabditis elegans Database. It can refer to a
database and data concerning the nematode C. elegans, or to the database
software alone. This document is concerned primarily with the latter meaning.
ACEDB is being adapted by many groups to organize molecular biology data about
the genomes of diverse species [Q4 gives contact information]. 

ACEDB allows for automatic cross-referencing of items during loading and allows
for hypertextual navigation of the links using a graphical user interface and
mouse. Certain special purpose graphical displays have been integrated into the
software. These reflect the needs of molecular biologists in constructing
genetic and physical maps of genomes. 

ACEDB was written and developed by Richard Durbin (MRC LMB Cambridge, England)
and Jean Thierry-Mieg (CNRS, Montpellier, France), beginning circa 1990. It is
written in the C programming language and uses the X11 windowing system to
provide a platform independent graphical user interface. The source code is
publicly available [See Q3]. Durbin & Thierry-Mieg continue to develop the
system, with contributions from other groups including Lawrence Berkeley
Laboratory and the Integrated Genomic Database (IGD) project headed by Otto
Ritter. 

A description by Durbin & Thierry-Mieg: ACEDB does not use an underlying
relational database schema, but a system we wrote ourselves in which data are
stored in objects that belong in classes. This is nevertheless a general
database management system using caches, session control, and a powerful query
language. Typical objects are clones, genes, alleles, papers, sequences, etc.
Each object is stored as a tree, following a hierarchical structure for the
class (called the "model"). Maps are derived from data stored in tree objects,
but precomputed and stored as tables for efficiency. The system of models allows
flexibility and efficiency of storage --missing data are not stored. A major
advantage is that the models can be extended and refined without invalidating an
existing database. Comments can be added to any node of an object. 

Return to List of Questions 


Q1: What is the current version of ACEDB?
+++++++++++++++++++++++++++++++++++++++++

A1:
+++

(This answer refers to the software not the C. elegans data.) 
Current version is 4_1 (as of 10 August 1995). 

A test (beta) version of ACEDB 4.0b4 (5/95) is available. 

A Macintosh version is available as version 2.0b4. 

To retrieve the software see Q3. 
To be kept informed of new releases see Q9. 

Return to List of Questions 


Q2: What hardware/software do I need to run ACEDB?
++++++++++++++++++++++++++++++++++++++++++++++++++

A2:
+++

The software is available as source code, so you may be able to get it working
on any machine, with effort. It is also available in binary (pre-compiled)
format for a variety of machines. To retrieve the software see Q3. 

 o Unix and X11: 
    o Sun/SunOS 4.x 
    o Sun/Solaris 
    o DEC DECstation3100, 5100 etc. 
    o DEC Alpha/OSF-1 
    o Silicon Graphics Iris series 
    o PC 386/486/Pentium with Linux (free Unix) Jeff Bryer,
      jbryer@darwin.mbb.sfu.ca and Ken Clark provide a linux version of 4.1 and
      a complete C. elegans data set at trog.mbb.sfu.ca in /pub/acedb as
      bin.linux.4_1.tar.Z. 
    o There exist, or have existed, ports onto Alliant, Hewlett- Packard, IBM
      R6000, Convex. You may have to contact the developer responsible for the
      port to make these real. 
    o NeXT: contact Patrick Phillips at University of Texas, NeXTmail:
      patrick@wbar.uta.edu email: phil@decster.uta.edu 
 o Macintosh: 
    o [Contributed by Frank Eeckman] Macace is distributed as a self-extracting
      archive that contains the application, the wspec files, and a fully up to
      date database. macace 3.0 is available with an updated 21bdb database.
      Please send all questions/bug reports to eeckman@llnl.gov A native powerPC
      version is available as well. Macace needs a macintosh with > 16 MBytes of
      RAM, and a 17" color monitor is preferred. System 7 or greater is
      required. For the multimedia extensions Quicktime 1.0 is required. Please
      add your name to our mailing list by sending email to eeckman@llnl.gov. It
      is our belief that for cost savings a powerPC mac will beat the advertised
      linux-intel combination. Macace is fully compatible with xace, but
      includes some multimedia extensions (picture and movie support) not found
      in the unix versions. 
 o ACEDB for The NEC EWS4800 is available via anonymous ftp at ftp.nec.co.jp
   (192.135.93.2) in /pub/packages/acedb/ace2. Contact Tohru Sano Fundamental
   Research Laboratories NEC Corporation Tsukuba, 305, JAPAN, e-mail:
   sano@exp.cl.nec.co.jp, FAX: +81-298-56-6136, VOICE: +81-298-50-1507 

(Here at the Institute of Forest Genetics we run ACEDB on a Sun Microsystems
SPARCstation II, and users can interact using Macintoshes and PC-clones by using
X11 implementations for the personal computers and a LAN. --bks) 

X11 fonts note: ACEDB uses fonts listed in the xfonts.wrm file. If you install
new fonts on your machine be sure to run bldfamily(1) so that they are
available. 

Return to List of Questions 


Q3: Where can I get ACEDB?
++++++++++++++++++++++++++

A3:
+++

The standard ACEDB source and binaries are available in the following public
access accounts (anonymous ftp sites) accessible via Internet: 

 o lirmm.lirmm.fr in pub/acedb 
 o cele.mrc-lmb.cam.ac.uk in pub/acedb 
 o ncbi.nlm.nih.gov in repository/acedb 
 o bioinformatics.weizmann.ac.il in pub/databases/acedb. 

MacAce is available from: 

 o genome.lbl.gov in pub/macace 
 o cele.mrc-lmb.cam.ac.uk in pub/acedb/macace 

Linux; ACEDB version 4.1 (and earlier versions) for Linux 2-10: 

 o trog.mbb.sfu.ca /pub/acedb as bin.linux.4_1.tar.Z. 

ACEDB for The NEC EWS4800: 

 o ftp.nec.co.jp in /pub/packages/acedb/ace2. 

Return to List of Questions 


Q4: What ACEDB databases exist?
+++++++++++++++++++++++++++++++

A4:
+++

In alphabetic order by Database name
------------------------------------

[Curators, please submit changes as new paragraphs] 

Database : AaeDB
Species : Aedes aegypti (Mosquito)
Last_update : December 1994
ACEDB_version : 3.0
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Curator : Martin Ferguson, martinf@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu

Database : AAtDB
Species : Arabidopsis thaliana
Current version : 3-5
Last_update : August 1995
Curator : John Morris
Contact : curator@frodo.mgh.harvard.edu
Availability : UNIX and Macintosh versions via anonymous ftp
FTP : Macintosh version - weeds.mgh.harvard.edu in aatdb/MacAAtDB
FTP : UNIX version - weeds.mgh.harvard.edu in aatdb/aatdb.3x
FTP : probe.nalusda.gov in pub/aatdb
Gopher : weeds.mgh.harvard.edu/
Gopher : probe.nalusda.gov:7004/
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://weeds.mgh.harvard.edu/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : AboutDB
Curator : Staffan Bergh, staffan@biochem.kth.se
Subject : ACEDB itself (meta-meta-metadata)
ACEDB_version: 3.0
Last_update : July 1995
WWW : http://www.biochem.kth.se/AboutDB.html 

Database : ACeDB
Species : Caenorhabditis elegans
Current version: 4-8
Curator : Jean Thierry-Mieg, mieg@kaa.crbm.cnrs-mop.fr
Curator : Richard Durbin, rd@mrc-lmb.cam.ac.u
Curator : Sylvia Martinelli, sylvia@sanger.ac.uk
Last_update : August 1995
Availability: Unix and Macintosh versions via anonymous ftp
FTP: USA - ncbi.nlm.nih.gov in repository/acedb
FTP: England - ftp.sanger.ac.uk in pub/acedb
FTP: France - lirmm.lirmm.fr in genome/acedb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/other/ 

DataBase : AceMap
Species : Homo sapiens
Subject : Physical mapping YAC data for human chromsome X
ACEDB_version : 3.0
Curator : Hugues Roest Crollius, hrc@gea.lif.icnet.uk
Curator : Mark Ross, humanX@gea.lif.icnet.uk
Curator : Richard Mott, rmott@gea.lif.icnet.uk
Availability : beta release of the X chromosome data/models via anonymous ftp
FTP : ftp.icnet.uk in icrf-public/GenomeAnalysis/X/acemap
Comment: Get the README file in the directory above.
Contact : Genome Analysis Laboratory, Imperial Cancer Research Fund, 44
Lincoln's Inn Fields, London WC2A 3PX, UK
Last_update : August 1994 

Database : AGsDB (A Genus species Database)
Species : Aspergillus nidulans
Species : Neurospora crassa
Species : Bos taurus (cow)
Species : Homo sapiens anchor loci
Species : Gossypium hirsutum (cotton)
Species : Neurospora crassa
Species : Homologs of Aspergillus cell cycle loci for budding and fission yeast
Curator : Leland Ellis, leland@straylight.tamu.edu
Last_update : March 1994
ACeDB_version : 3.0
Subject: Contains extensions to the Human C21 Models to provide for multiple
species, and queries between species via Homologs (e.g., cell cycle loci with
links via Homologs between Aspergillus and budding C. cerevisiae) and fission
(S. pombe yeast); interacting loci via defined Interactions for each locus
Revision : AAnDB for Aspergillus nidulans and ABtDB for Bos taurus (cow) have
been folded into AGsDB, and are not being developed futher as individual species
databases.
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/other/
WWW : http://keck.tamu.edu/cgi/agsdb/agsdbserver.html 

Database : Alfagenes
Species : Medicago sativa (alfalfa)
Curator : D. Z. Skinner, dzolek@ksu.ksu.edu
Telephone : (913) 532-7247
ACEDB_version : 3.0
Last_Update : July 1995
FTP : probe.nalusda.gov in pub/alfagenes
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : BeanGenes
Species : Phaseolus and Vigna
Curator : Phillip E. McClean, mcclean@beangenes.cws.ndsu.nodak.edu
ACEDB_version : 1.0
Last_updated : January 1995
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : ChlamyDB
Species : Chlamydomonas
Curator : Elizabeth Harris
Contact : chlamy@acpub.duke.edu
ACEDB_version : 3.0
Data_version : 1.2
Last_update : August 1995
Availability : Macintosh and UNIX versions via anonymous ftp
FTP : probe.nalusda.gov in pub/chlamydb
Gopher : ftp.duke.edu/11/pub/chlamy
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : CIMMYT (Wheat International Nursery Data)
Species : Triticum spp.
ACEDB_version : 4.0
Last_update : September 1995
Curator : Hector Sanchez, hsanchez@cimmyt.mx
FTP : probe.nalusda.gov in pub/cimmyt
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : CottonDB
Species : Gossypium hirsutum (cotton) and related species
PI : Russell J. Kohel (rjk0339@acs.tamu.edu), USDA-ARS, Southern Crops Research
Laboratory, 2765 F&B Road, College Station, Texas 77845
Curator : Gerard R. Lazo, lazo@tamu.edu
Curator : Sridhar Madhavan, msridhar@tamu.edu
Phone : 409-260-9311
Fax : 409-260-9333
Last_update : January 1995 (version 95.1)
ACEDB_version : 3.0
FTP : probe.nalusda.gov in pub/cottondb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
Data_submission_form : http://algodon.tamu.edu/ 

Database : CSNDB
Focus : Cell Signalling Molecules and Interactions
Contact : Takako Igarashi, National Insitute of Health Sciences, Division of
Chem-Bio Informatics, Setagaya-ku, Tokyo, Japan 158, taka@nihs.go.jp 

Database : EofD (Encyclopaedia of the Drosophila)
Species : Drosophilidae (primarily D. melanogaster)
Availability : Macintosh CD-ROM and SunOS executables via anonymous ftp
Developer : Suzanna Lewis, suzi@fly2.berkeley.edu
Developer : Cyrus Harmon, sly@fly2.berkeley.edu
Developer : Edward Welbourne, eddy@gen.cam.ac.uk
Collaborator : The FlyBase Consortium, flybase-help@morgan.harvard.edu
Collaborator : The Berkeley Drosophila Genome Project,
flygenome@maillink.berkeley.edu
Gopher : fly.bio.indiana.edu:70+/11/Flybase
WWW : http://fly2.berkeley.edu:3512/EofD.html 

Database : EthnobotDB (orldwide plant uses)
Species : wide range of plant species
ACEDB_version : 4.0
Last_update : June 1995
Comment : Converted to ACEDB from the original SQL database.
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov 
Curator : James A. Duke, ngrljd@ars-grin.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : FoodplantDB (Native American Food Plants)
Species : Over 1,100 plant species
ACEDB_version : 4.0
Last_update : May 1995
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov 
Curator : James A. Duke, ngrljd@ars-grin.gov
Comment : Converted to ACEDB from ORACLE.
Comment : Data originally from a publication by Yanovsky, Elias. 1936. Food
Plants of the North American Indians. USDA Miscellaneous Publication Number 237.
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : GrainGenes
Species : Wheat, barley, oats, relatives
Curator : David E. Matthews, matthews@greengenes.cit.cornell.edu
PI : Olin D. Anderson, oandersn@pw.usda.gov
ACEDB_version : 4_1
Data_version : 1.4+
Last_update : September 1995
FTP : probe.nalusda.gov in pub/graingenes
Gopher : greengenes.cit.cornell.edu/
Gopher : probe.nalusda.gov:7002
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://wheat.pw.usda.gov/graingenes.html 

Database : IGD (Integrated Genomic Database)
Species : Homo sapiens
Subject : Chromosome 21
Availability : September 1994 by ftp, on-line server October 1994
Contact : Otto Ritter, o.ritter@dkfz-heidelberg.de
Contact : Jean Thierry-Mieg, mieg@kaa.cnrs-mop.fr
Contact : Nicole Creau-Goldberg, creau@arthur.citi2.fr
Contact : Jean-Maurice Delabar, delabar@arthur.citi2.fr
WWW : http://moulon.inra.fr/acedb/igd.html
Description : IGD (Integrated Genomic Database) aims to integrate multiple
public general molecular biology and human genome specific databases into single
logical database with unified interface to existing analysis tools. From data
produced by the 4th International Workshop on Chromosome 21
(Genomics,1993,18,735-744) and from data provided by or taken from the following
databases and data repositories: GDB, OMIM, EMBL, CEPH, Genethon, UKProbeBank,
and RLDB. 

Database : LeishDB
Species : Leishmaia major, L. infantum, L. peruviana, L. donovani and others
PI : Jennie Blackwell
PI : Al Ivens
Last_update : September 1995
ACEDB_version : 4.1
Contact : Matin Aslett, ma10025@cus.cam.ac.uk
FTP : ftp://parsun1.path.cam.ac.uk
WWW : http://parsun1.path.cam.ac.uk/
Curator : Martin Aslett
Curator : Howard Cobb

Database : LIGM-DB
Curator : Veronique Giudicelli
Focus : genetic and physical mapping of loci of Immunoglobulins and Tcell
receptors
PI : Marie-Paule Lefranc
Contact : Veronique Giudicelli LIGM IGMM UMR CNRS 9942 BP 5051 Rte de Mende
34000 Montpellier giudi@ligm.crbm.cnrs-mop.fr 

Database : MaizeDB
Species : Zea mays L. ssp. mays and related species
Latest_release : April 1995
Acedb_version : 3.3
Comment : MaizeDB is a periodically extracted ACeDB front end for the Maize
Genome Database, MaizeDB, a SYBASE database, implemented using Genera software,
developed by Stan Letovsky.
Comment : Genera provides (1) up-to-the-minute form internet access to SYBASE
databases, both for query (WWW and APT) and data entry (APT only); (2) database
design alterations by systems administrators; (3) gopher file extraction.
Comment: MaizeDB uses WWW record-to-record hard-links to 16 external databases
for (1) annotated sequences: GenBank, dbEST, GenoBase, PIR, SwissProt, Prosite,
ENZYME; (2) other species genome information: AAtDB(Arabidopsis), RiceGenes,
GrainGenes, SaachDB (yeast), CGSC(E. coli), XLocus, RiceGenes, GrainGenes (3)
germplasm: GRIN. 
Data : Over 100,000 records include: 6513 mapped loci (located to chromosome or
better) including 1081 mapped genes and 1937 mapped probed sites (gene
candidates); 2448 probes; 2460 map scores; 1551 gel patterns
(Probe/Enzyme/Stock); 8777 stocks; 18,100 Variations (alleles, DNA
polymorphisms, rearrangements, etc); 596 phenotypes; 317 traits; 715 gene
products; 6158 bibliographic references; 2200 researchers with addresses.
FTP : probe.nalusda.gov in pub/maizedb
Gopher : gopher.agron.missouri.edu
Gopher : probe.nalusda.gov:7000/11/genome.databases/
Telnet : telnet teosinte.agron.missouri.edu login as guest, use password:
corncob
WWW : http://www.agron.missouri.edu/top.html
WWW : http://probe.nalusda.gov:8300/plant/
WWW Genera information : http://gdbdoc.gdb.org/letovsky/genera/genera.html
Funding : MaizeDB USDA/ARS to E. Coe
Funding : Genera NSF BIR 92-01652 to S. Letovsky and M. Berlyn
Curator/PI : Ed Coe, ed@teosinte.agron.missouri.edu
Curator : Mary Polacco, maryp@teosinte.agron.missouri.edu
Assoc Curator : Pat Byrne, byrne@teosinte.agron.missouri.edu QTL data
Assoc Curator : Georgia Davis, gdavis@teosinte.agron.missouri.edu Map data
Assoc Curator : Marty Sachs, Maize Stock Center, msachs@uiuc.edu Genetic Stock
data
Assoc Curator : Christiane Fauron, FAURON@GENE1.med.utah.edu Mitochondrion
genome
Assoc Curator : Carolyn Wetzel, cmwetzel@iastate.edu Chloroplast genome
Assoc Curator : Steve Rodermel, S1SRR@ISUVAX.IASTATE.EDU Chloroplast genome
Design : Stan Letovsky, letovsky@gdb.org
Design : Mary Berlyn, mary@fetalpig.biology.yale.edu
Systems Manager : Denis Hancock, dhancock@teosinte.agron.missouri.edu
Contact : db_request@teosinte.agron.missouri.edu
Last_update : 11 April 1995 

Database : Mendel (plant wide gene names)
Species : wide range of plant species
Subject : standardized designations for sequenced genes
Comment : The purpose is to provide a common system of nomenclature for
substantially similar genes across the plant kingdom. Mendel is maintained by
the Commission on Plant Gene Nomenclature.
ACEDB_version : 4.0
Last_update : July 1995
Curator : Carl Price, price@mbcl.rutgers.edu
Curator : Ellen Reardon, reardon@mbcl.rutgers.edu
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : Millet Genes
Species : Pennisetum Glaucum (Pearl Millet)
ACEDB_version : 4.1
Availablity : Local
Curator : Matt Couchman, couchman@bbsrc.ac.uk
Curator : Katrien Devos, devos@bbsrc.ac.uk

DataBase : Mousedb
Species : Musculus Musculus
Species : Homo Sapiens
ACEDB_version : 3.0 with extensions to define and display cytogenetic data.
Description : Mouse genome data from the published literature, including mouse
genes with phenotypic effects, chromosome anomalies, imprinted regions and
man-mouse homologies with associated pathological disorders. The maps are
consensus ones. They use data, such as the HIS and anomaly data, to show
alignments between the genetic and cytogenetic maps.
Curator : Rachael Selley, rselley@har-rbu.mrc.ac.uk
PI : Mary Lyon
PI : Jo Peters
Availability : Mousedb is available publicly from the UK HGMP Resource Centre's
computing service via the INTERNET. For user id. please contact Administration,
HGMP Resource Centre, Hinxton Hall, Cambridgeshire CB10 1RQ, UK. 
Tel: (+44) 1223 494520 Fax: (+44) 1223 494510 
Contact : Rachael Selley, MRC Radiobiology Unit, Chilton, Didcot, Oxon OX11 ORD
Last_update : July 1995 

Database : MPNADB (Medicinal Plants of Native America)
Species : Over 2,100 plant species
Curator : Daniel E. Moerman, dmoerman@umich.edu
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov - ACEDB version 
Comment : MPNADB is based on a two-volume book of the same name published in
1986 by the Museum of Anthropology of the University of Michigan. MPNADB was
first developed at the University of Michigan in DBase II.
ACEDB_vertion : 4.0
Last_update : June 1995
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : MycDB
Species : Mycobacteria
Comment : MycDB is a collation of data on the mycobacteria, causative agents of
tuberculosis and leprosy. It is centered on the mapping and sequencing projects
under way in M.leprae and M.tuberculosis.
Curator : Staffan Bergh, staffan@biochem.kth.se
Last_update : July 1995
ACEDB_version : 3.0
Data_version : 3-8 (June 18, 1995)
FTP : www.biochem.kth.se (130.237.52.64) in pub/MycDB
FTP : ftp.pasteur.fr (157.99.64.12) in pub/MycDB
FTP : bioinformatics.weizmann.ac.il (132.76.55.12) in pub/databases/acedb/mycdb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://www.biochem.kth.se/MycDB.html
WWW : http://probe.nalusda.gov:8300/other/ 

Database : OMIA (Online Mendelian Inheritance in Animals)
Species : wide range of animal species
Subject : gene and phene (familial trait or phenotype) information
Comment : MIA is modeled after Victor McKusick's Mendelian Inheritance in Man
(MIM) database and was developed at the University of Sydney, Australia, in
Advanced Revelation.
Curator : Frank Nicholas, frankn@doolittle.vetsci.su.oz.au
Curator : Gail Juvik, gjuvik@nalusda.gov - ACEDB version
ACEDB_vertion : 4.0
Last_update : September 1995
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/animal/
WWW : http://morgan.angis.su.oz.au/BIRX/phenes_form.html 

Database : PhytochemDB (Plant Chemicals)
Species : wide range of plant species
Subject : Consists primarily of plant chemical data, including quantity,
taxonomic occurence, and chemical activity.
Comment : Converted to ACEDB from the original SQL database.
ACEDB_version : 4.0
Last_update : June 1995
Data_version : July 1994
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov 
Curator : James A. Duke, ngrljd@ars-grin.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : PomBase
Curator : Sean Walsh, svw@sanger.ac.uk
Curator : Marie-Adele Rajendream
PI : Bart Barrell, barrell@sanger.ac.uk
Species : Schizosaccharomyces pombe
ACEDB_version : 4.1
Last_update : September 1995
FTP : ftp.sanger.ac.uk in pub/PomBase 

Database : PVP (Plant Variety Protection)
Species : Glycine max (soybeans)
Subject : Data about plant varieties that have been granted a Certificate of
Protection by the Plant Variety Protection Office.
Curator : Stephen M. Beckstrom-Sternberg, sbeckstr@nalusda.gov - ACEDB version
ACEDB_version : 4.0
Last_update : June 1995
Contact: The Plant Variety Protection Office, Room. 500, National Agriculture
Library, 10301 Baltimore Blvd., Beltsville, Maryland 20705
Telephone : 301-504-5518
Fax : 301-504-5291
Email : Jeff Strachan, strachan@locus.nalusda.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/ 

Database : RiceGenes
Species : Oryza sativa
Curator : Edie Paul, epaul@nightshade.cit.cornell.edu
PI : Susah McCouch
ACEDB_version : 3.0
Last_update : July 1995
FTP : probe.nalusda.gov in pub/ricegenes
Gopher : nightshade.cit.cornell.edu
Gopher : probe.nalusda.gov:7007
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : SacchDB
Species : Saccharomyces cerevisiae
Subject : Budding (common baker's) Yeast Genome
ACEDB_version : UNIX 2.0, MacAce 2.0b4
Last_update : September 1995
Data_version : 2.4.12
Data : All Saccharomyces genes contained in the Registry of Gene Names. Results
of the completed chromosomal sequencing projects have been integrated into the
database. Physical Maps based on DNA sequencing projects, hybridization to the
Olson/Riles prime filter grids, and restriction mapping. For the completely
sequenced chromosomes the Olson prime clones have been re-mapped (on the
computer) to the DNA sequence. Saccharomyces DNA sequences contained within
GenBank are incorporated. Literature references, most including abstracts, for
the information contained within the database. Gene protein product information
obtained from the YPD database (Garrels and Latter, CSHL) and the literature.
Genetic Maps including the underlying two point tetrad data. Including all
tetrad data reported in previous additions of the Mortimer Yeast Maps.
FTP : genome-ftp.stanford.edu in pub/yeast/SacchDB
FTP : ncbi.nlm.nih.gov in repository/SacchDB
Gopher : genome-gopher.stanford.edu
WWW : http://genome-www.stanford.edu/
Funding : National Center for Human Genome Research, NIH
PI : David Botstein, botstein@genome.stanford.edu
Project Manager/Curator : Mike Cherry, cherry@genome.stanford.edu
Curator : Selena Dwight, dwight@genome.stanford.edu
Curator : Cathy Ball, ball@genome.stanford.edu
Curator : Rita Schmidt, bleb@genome.stanford.edu
Curator : Barbara Dunn, bdunn@genome.stanford.edu
Curator : Caroline Adler, adler@genome.stanford.edu
Programmer : Karen Davis, karen@genome.stanford.edu
Sys. Admin : Mark Schroeder, mark@genome.stanford.edu
Contact : yeast-curator@genome.stanford.edu
Data_Submission : yeast-curator@genome.stanford.edu 

Database : SolGenes
Subject : Solanaceae - tomato, potato, pepper
Curator : Clare Nelson, cnelson@nightshade.cit.cornell.edu
PI : Steve Tanksley
Release : ACEDB 3.0
Last_update : May 1995
FTP : probe.nalusda.gov in pub/solgenes
Gopher : nightshade.cit.cornell.edu:71
Gopher : probe.nalusda.gov:7006
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : SorghumDB
Species : Sorghum bicolor (L.) Moench
PI : Keith F. Schertz, schertz@tamvm1.tamu.edu
USDA-ARS, Dept. of Soil & Crop Sciences, Texas A&M University, College Station,
TX 77843-2474
Phone : (409) 260-9252
FAX : (409) 845-0456
Curator : Najeeb U. Siddiqui, nus6389@tam2000.tamu.edu
Southern Crop Improvement Facility, Crop Biotechnology Center, Texas A&M
University, College Station, TX 77843-2123
Phone : (409) 862-1523
FAX : (409) 862-4790
Last_update : September 1995
ACEDB_version : 3.0
Data_version : 2.0
FTP : probe.nalusda.gov in pub/sorghumdb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/ 

Database : SoyBase
Species : Glycine max (Soybeans) and related species
PI : Randy Shoemaker
Curator : David Grant, dgrant@mendel.agron.iastate.edu
Curator : Marica Imsamde, mimsande@mendel.agron.iastate.edu
Contact : Dave Schrader, schrader@mendel.agron.iastate.edu
ACEDB-Version : 3.7
Last_update : August 1995
FTP : probe.nalusda.gov in pub/soybase
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://mendel.agron.iastate.edu:8000/main.html 

Database : Syndb
Species : Homo sapiens, Mus musculus
Subject : STS content mapping & directed sequencing of Human Chromosomes 21,5
with Mouse for syntenic comparison
ACEDB_version : acedb v3.3 plus moulon server
Last_update : October 1994
FTP : genome.lbl.gov in pub/acedb/
WWW : http://genome.lbl.gov/Genome/acepage.html
Curator : Donn F. Davy, DFDavy@lbl.gov
Contact : Arun K. Aggarwal, aggarwal@genome.lbl.gov
PI : Michael Palazzolo
PI : Chris Martin
PI : Jan-Fang Cheng, jcheng@genome.lbl.gov 

Database : Toxo
Species : Toxoplasma gondii
PI : Jennie Blackwell
PI : Jim Ajioka
Last_update : September 1995
ACEDB_version : 4.1
Contact : Martin Aslett, ma10025@cus.cam.ac.uk
FTP : parsun1.path.cam.ac.uk
WWW : http://parsun1.path.cam.ac.uk/
Curator : Martin Aslett
Curator : Howard Cobb

Database : TreeGenes
Species : Forest trees
ACEDB_version : 3.0
Last_update : July 1995
Curator : Bradley K. Sherman, bks@s27w007.pswfs.gov
PI : David B. Neale, dbn@s27w007.pswfs.gov
Contact : Dendrome@s27w007.pswfs.gov
FTP : probe.nalusda.gov in /pub/treegenes
Gopher : s27w007.pswfs.gov/
Gopher : probe.nalusda.gov:7508/
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://s27w007.pswfs.gov/ 

Database : Trypbase
Species : Trypanosoma brucei
PI : Sara Malville
Contact : sm160@mole.bio.cam.ac.uk
Comment : Under development, feedback welcome.
ACEDB_version : 4.0 

Database : 21Bdb
Species : Homo sapiens
Subject : STS content mapping and sequencing of Human Chromosome 21
ACEDB_version : acedb.1-10 plus moulon server
Curator : Donn F. Davy, DFDavy@lbl.gov
Contact : Arun K. Aggarwal, aggarwal@genome.lbl.gov
PI : Michael Palazzolo
PI : Chris Martin
PI : Jan-Fang Cheng, jcheng@genome.lbl.gov
Last_update : April 1994
FTP : ftp://genome.lbl.gov in pub/acedb/
WWW : http://genome.lbl.gov/Genome/acepage.html 

Database : 22ace
Species : Homo sapiens
Subject : Physical map of human chromosome 22, genomic sequencing and more
ACEDB_version : 4.1
Curator : Ian Dunham, id1@sanger.ac.uk
Curator : Gareth Maslen, glm@sanger.ac.uk
PI : Ian Dunham
Last_update : August 1995
FTP : ftp.sanger.ac.uk in pub/human/chr22/physical_map/
WWW : http://www.sanger.ac.uk/hum22/

Database : VoxPop
Species : Populus species
Curator : Carl G. Riches, cgr@poplar1.cfr.washington.edu
PI : Reinhard F. Stettler, STETTLER@coyote.cfr.washington.edu
Last_update : September 1993
ACEDB_version : 1.9
FTP : poplar1.cfr.washington.edu in /pub/
Gopher : poplar1.crf.washington.edu 

Return to List of Questions 


Q5: What documentation exists for ACEDB?
++++++++++++++++++++++++++++++++++++++++

A5:
+++

From Sam Cartinhour: The ACEDB Documentation Server is a repository for
documentation concerned with "A C. elegans Data Base", the generic genome
database software designed by Richard Durbin (MRC, UK) and Jean Thierry-Mieg
(CNRS, France). The server is intended as a resource for developers, curators,
and end-users of all (not just plant) databases derived from ace. Eventually we
hope to offer all kinds of documentation, from reprints to (technical) gossip.
The ACEDB documentation server is sponsored by the Plant Genome Database Project
at the National Agricultural Library (USDA). The documentation server is listed
on the home page for the Agricultural Genome World Wide Web Server at 
http://probe.nalusda.gov:8000 . 

Primary documents from the developers are: 

 o acedb -- A C. elegans Database: I. Users' Guide. 
 o acedb -- A C. elegans Database: II. Installation Guide. 
 o acedb -- A C. elegans Database: III. Configuration Guide. 
 o Syntactic Definitions for the ACEDB Data Base Manager --Jean Thierry-Mieg and
   Richard Durbin (1991-) 

Get By anonymous ftp from ncbi.nlm.nih.gov in repository/acedb: 
ftp://ncbi.nlm.nih.gov/respository/acedb/doc*tar.Z and 
ftp://weeds.mgh.harvard.edu/acedb_doc . The files are in TeX (Jean Thierry-Mieg
suggests latex xxx.tex; dvi2ps xxx.dvi > xxx.ps; lpr xxx.ps) and PostScript. 

The Proceedings from the May 1995 ACEDB Conference are available at 
http://probe.nalusda.gov:8000/acedocs/ace95/index.html A final summary report is
available at http://probe.nalusda.gov:8000/acedocs/ace95/ace95.final.html . 

Japanese language guides: _Japanese ACEDB Guide Ver.1.2._ _ACEDB ver.2 for NEC
engineering workstation EWS4800 series_ are available in PostScript via
anonymous ftp at ftp.nec.co.jp as /pub/packages/acedb/acemanjp.1_2.ps.Z . There
is a Japanese language ACEDB FAQ available at 
http://www.cbi.or.jp/~sano/acemanjp12/index.html 

SampleDB, by Dave Matthews, is an ACEDB database constructed to demonstrate
features of ACEDB, especially map and sequence displays. Anonymous ftp to 
probe.nalusda.gov:pub/acedocs/sampledb 

You will find interesting documents in the wdoc subdirectory of the ACEDB
distribution. 

The Australian National Genomic Information Service has prepared good
documentation of the C. elegans version as Angistute.ps and angistute.hqx 
available by anonymous ftp at ncbi.hih.gov in repository/acedb/ace2. 

Cherry, J.M., Cartinhour, S.W., and Goodman, H.M. (1992) AAtDB, An Arabidopsis
thaliana Database. Plant Molecular Biology Reporter 10 (4): 308-309,409-410 

Tutorial manual for AAtDB: Cartinhour, S., Cherry, J.M., and Goodman, H.M.
(1992) An Introduction to ACeDB: For AAtDB, An Arabidopsis thaliana Database.
Massachusetts General Hospital. (Available on request in printed form from the
AAtDB curator). URL : http://genome-www.stanford.edu/docs/aatdb_man.html . 

A description of ACEDB: Cherry, J.M. and Cartinhour, S.W. (1994) ACEDB, A tool
for biological information. in Automated DNA Sequencing and Analysis, edited by
M. Adams, C. Fields, and C. Venter. Academic Press, pages 347-356. [text is
available through ftp or gopher from weeds.mgh.harvard.edu] URL : 
http://probe.nalusda.gov:8000/acedocs/overview.html . 

Another description of ACEDB for physical mapping projects: Dunham, I., Durbin,
R., Mieg, J-T & Bentley, D.R. (1994) Physical mapping projects and ACEDB, in
Guide to Human Genome Computing. Ed. Bishop, M.J. Academic Press, pages 111-158.
[text is available through ftp or gopher from weeds.mgh.harvard.edu] 

Return to List of Questions 


Q6: What other resources are available for ACEDB?
+++++++++++++++++++++++++++++++++++++++++++++++++

A6:
+++

Perl and WWW tools
++++++++++++++++++

> The AGIS server at the National Agricultural Library provides a tool set for
integrating version 4 of ACEDB with perl and the World-Wide Web. The archive is 
ftp://probe.nalusda.gov/pub/tools/acelib.tar.gz 

For a general tool for converting data to ACEDB format input files, Joachim
Baumann (joachim.baumann@informatik.uni-stuttgart.de) has written the Perl
program TextConvert, available at 
ftp.informatic.uni.stuttgart.de/pub/DART/TextConvert . 

The Developers' Archive
+++++++++++++++++++++++

Mike Cherry maintains an archive of tools that may be useful in curating ACEDB
databases. It can be reached by anonymous ftp at URL 
ftp://weeds.mgh.harvard.edu/acedb_dev/ or via gopher at 
gopher://genome-gopher.stanford.edu:70/11/ftp 

If you have a contribution place it in
ftp://weeds.mgh.harvard.edu/acedb_dev/incoming/ and send a message to Mike
(cherry@genome.stanford.edu). 

The Biosci conference bionet.software.acedb
+++++++++++++++++++++++++++++++++++++++++++

There is a USENET/Biosci conference titled bionet.software.acedb created
expressly for discussion of ACEDB. The best way to interact with the Biosci
conferences is via a newsreader like rn, trn, tin or a WWW browser. Consult your
system administrator for more information. 

If you do not have access to the Biosci conferences via a newsreader (e.g. rn,
trn, tin) you can participate in the conference by electronic mail. To subscribe
to the e-mail version of the conference send email to biosci-server@net.bio.net
(UK, European readers use biosci@uk.ac.daresbury or biosci.daresbury.ac.uk) with
no subject line and only the message subscribe ACEDB-SOFT in the body. To
unsubscribe send the message unsubscribe ACEDB-SOFT to the same address. This is
an automated service. Your e-mail address will be taken from the header of the
message that you send. If you then send mail to acedb@net.bio.net the mail will
be distributed to all subscribers and to the electronic conference. 

 o All of the articles in biosci.software.acedb are archived by Biosci at 
   gopher://gopher.bio.net/1/ACEDB 
 o Mike Cherry makes it possible to search past articles in
   biosci.software.acedb using WAIS at 
   gopher://genome-gopher.stanford.edu:80/77/.index/acedb-biosci and at URL 
   http://genome-www.stanford.edu/biosci_acedb.html . If your WWW browser is
   configured properly you may be able to read the newsgroup at 
   news:biosci.software.acedb 

. 

And more
++++++++

The AAtDB, Soybase, GrainGenes, Mace, and TreeGenes [see Q4] databases regularly
submit data to the Plant Genome Database at the National Agricultural Library
(NAL). Nal makes this data available via the WWW using an http server with URL: 
http://probe.nalusda.gov:8000/index.html You will also find a selection of
models.wrm files (schemata) for the various databases here. You will want to get
a "mosaic client" to examine this. 

AboutDB is a stab at an integrated info and project tracking database for the
'Greater ACEDB Community'. It was conceived and implemented by Staffan Bergh
(staffan@biochem.kth.se), the 'coordinator', during the ace94 workshop in
Montpellier, based on an earlier effort by John McCarthy. The aim is to collect
information on all aspects of ACEDB use as a database manager. Currently it
contains information on Databases implemented in ACEDB, Colleagues in the
community, some Tools for >curators of ACEDB databases and some of the
information on 'magic tags' collected during the ace94 workshop. AboutDB can be
reached at URL: http://kiev.physchem.kth.se/AboutDB.html 

Other URL's that readers with mosaic clients might want to examine are:

 o http://moulon.inra.fr/acedb/acedb.html for C. elegans data 
 o http://kiev.physchem.kth.se/MycDB.html for Mycobacterium data 
 o http://moulon.inra.fr:8001/acedb/igd.html for an integrated genome database. 

For information on how these were created see 
http://moulon.inra.fr/acedb_conf_eng.html and en francais 
http://moulon.inra.fr/acedb_conf.html A how-to manual on the Moulon server is
available at http://keck.tamu.edu/cgi/staff/ace-mosaic-howto.html 

The Genome Computing Group, Lawrence Berkeley Laboratory, has an anonymous ftp
service at machine genome.lbl.gov which contains: 

 o flydb - LBL's Drosophila Acedb-style database 
 o 21bdb - LBL's Human Chromosome 21 Acedb-style database 
 o querdb - LBL's query-language extensions to Acedb 
 o metadata - LBL's compendium of Acedb database schema variants 
 o macace-aatdb-demo.hqx - pre-release Acedb MacIntosh version 
 o There is also a repository of contributed software for data conversions and
   the like. 

[From Otto Ritter] IGD - the Integrated Genomic Database - is an international
project of DKFZ, Heidelberg (Germany), CNRS, Montpellier (France), ICRF, London
(UK), LBL, Berkeley (USA), and MRC, London/Cambridge, (UK). IGD is an extensible
object-oriented distributed information management system with one global
schema, physical data integration at the back-end, and local data management at
the front-end. It supports local schema evolution and local data integration,
and has a potential for truly virtual "on-the-fly" integration (federation) of
its resource databases. Beside data integration, IGD provides graphical user
interface, client/server communication, and seamless interface to a growing
number of tools for structure, sequence, genetic, physical and comparative
mapping analysis. ACEDB is the IGD main software component for data management.
As a database, IGD integrates and references genome related data from public
sources. As an analysis tool, IGD provides uniform interface to existing
programs and program packages for tructure and sequence analysis, genetic and
physical map construction and analysis, etc. In addition to the major human and
mouse databases already planned SWISS-PROT/PIR, PDB, GDB, OMIM, CitDB, CEPH,
CHLC, CEPH-Genethon, Genbase, UK DNA ProbeBank, RLDB2, CAD, MGD, MouseBackcross
DB), crossreferences will be maintained to dataabases established around
specific model organisms (C.elegans, D. melanogaster, S. cerevisiae, pombe
etc.). Refs: 

 o 1/ Ritter,O.: The Integrated Genomic Database. in Computational Methods in
   Genome Research, edited by S.Suhai, Plenum, 57-73 (1994). 
 o 2/ Ritter,O., Kocab,P., Senger,M., Wolf,D., and Suhai,S.: Prototype
   Implementation of the Integrated Genomic Database, Computers and Biomedical
   Research, 27, 97-115 (1994) 

Computer staff for the UC Berkeley Drosophila physical mapping project the LBL
Human Chromosome 21 project, and the LBL plant genome projects meet regularly to
coordinate their ACEDB extension and development efforts, along with Frank
Eeckman, who is working on the Macintosh version of ACEDB (for further
information, contact jlmccarthy@lbl.gov). They also keep in close touch (via
email, personal visits, etc.) with their counterparts in Cambridge (Richard
Durbin et al), Montpellier Jean Thierry-Mieg et al), and the Interated Genome
Database project in Heidelburg (Otto Ritter, Detlef Wolf et al). 

Return to List of Questions 


Q7: How should ACEDB be cited?
++++++++++++++++++++++++++++++

A7:
+++

From the distribution: 
We realize that we have not yet published any "real" paper on ACEDB. We consider
however that anonymous ftp servers are a form of publication. We would
appreciate if users of ACEDB could quote: 
Richard Durbin and Jean Thierry Mieg (1991-). A C. elegans Database.
Documentation, code and data available from anonymous FTP servers at
lirmm.lirmm.fr, cele.mrc-lmb.cam.ac.uk and ncbi.nlm.nih.gov. 

Papers involved in database development could quote more precisely: 
I. Users' Guide. Included as part of the ACEDB distribution kit, 
II. Installation Guide. Included as part of the ACEDB distribution 
III. Configuration Guide. Included as part of the ACEDB distribution 
and the preprintkit available via anonymous ftp. Jean Thierry-Mieg and Richard
Durbin (1992). Syntactic Definitions for the ACEDB Data Base Manager. Included
as part of the ACEDB distribution. 

--Jean and Richard. 

Return to List of Questions 


Q8: Is ACEDB object-oriented?
+++++++++++++++++++++++++++++

A8:
+++

From the ACEDB User's Guide: 

A major current vogue in computer languages and database design is for
``object-oriented'' systems. It's also a source of lots of argument. We are just
trying to build a good system, and don't want to get caught in the crossfire,
but we do talk about organising our data into objects and classes. We have
undoubtedly been influenced by many of the ideas going around, but it isn't
likely our system would be regarded as kosher by the object- oriented community.
In particular there is no class hierarchy, nor inheritance, and it is written in
a modular but non-ideological way in straight C. However display and disk
storage methods are class dependent. 

In some ways the class hierarchy is replaced by our system of models and trees,
which seems to be rather unusual. We think it is very natural for the
representation of biological information, where for some members of a class a
lot might be known about some aspect, but for most only a little is known. 

The advantages of our sytem over a relational database, such as Oracle or
Sybase, is our ability to refine our descriptions without rebuilding the
database and the possibility of organising the storage of data on disk according
to their class, i.e. we store in a very different way the tree-objects and the
long stretches of DNA sequence. 

Return to List of Questions 


Q9: How can I get on/off the ACEDB announcements mailing list?
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

A9:
+++

To get on or off the mailing list send mail to rd@mrc-lmb.cam.ac.uk or
mieg@kaa.crbm.cnrs-mop.fr. New releases of the software are announced to this
list and very little else. The BIOSCI newsgroup bionet.software.acedb [See Q6
for details] is on the mailing list. 

Return to List of Questions 


Q10: When and where is the Next ACEDB Workshop?
+++++++++++++++++++++++++++++++++++++++++++++++

A10:
++++

The 1996 Workshop is not yet scheduled. 

If you would like to see some pictures of the ACEDB '94 Workshop in St. Matthieu
de Treviers, there are online collections: 

 o by Mike Cherry at
   http://genome-www.stanford.edu/~cherry/pics/acedb-94.pics.html ; 
 o by John Morris at http://weeds.mgh.harvard.edu/ace94/ace94.image.html ; 
 o and by Brad Sherman at ftp://s27w007.pswfs.gov/ACEDB/ace94pix.html 

Return to List of Questions 


Q11:Who prepared this document & where is the current version?
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

A11:
++++

This document will be posted monthly to the BIOSCI newsgroup
bionet.software.acedb and to USENET conference news.answers. It is intended to
be used as an index to ACEDB databases and to information about the database
software. 

The latest text version of the ACEDB FAQ should be available via anonymous ftp
at machine net.bio.net as file pub/BIOSCI/ACEDB/ACEDB.FAQ or at rtfm.mit.edu as 
pub/usenet/news.answers/acedb-faq . If you only have electronic mail, the FAQ
can be retrieved from mail-server@rtfm.mit.edu. 

There is an HyperText Markup Language (HTML) version of this document available
on the World Wide Web: http://probe.nalusda.gov:8000/acedocs/acedbfaq.html and 
http://s27w007.pswfs.gov/Homepage/acedbfaq.html There is a Japanese language FAQ
available at http://www.cbi.or.jp/~sano/acemanjp12/index.html 

Curators of ACEDB databases should take note of Question 4 and keep me apprised
of changes. 

Errors of commission or omission are unintentional. If I have forgotten to give
you credit please let me know. Please send comments and corrections to: 
acedbfaq@s27w007.pswfs.gov 

Major contributions in getting this FAQ off the ground were made by Mike Cherry,
John McCarthy, and Doug Bigwoody. Other contributors include: 

 o Lisa Lorenzen 
 o David Matthews 
 o Edie Paul 
 o Donn Davy 
 o Eric De Mund 
 o Sam Cartinhour 

Please cite as: 
Sherman,B.K., ACEDB Genome Database Software FAQ,
ftp://rtfm.mit.edu/pub/usenet/news.answers/acedb-faq,
http://probe.nalusda.gov:8000/acedocs/acedbfaq.html, 1993,1994,1995 approx. 50K
bytes. 

To add or modify information in this document, please send mail to:
acedbfaq@s27w007.pswfs.gov 

Bradley K. Sherman 
Dendrome Project 
Institute of Forest Genetics 
P.O. Box 245, Berkeley, CA, 94701 
Phone: 510-559-6437 Fax: 510-559-6440 

The Dendrome Project and TreeGenes are funded by the USDA ARS Plant Genome
Research Program. 

Return to List of Questions 

End of ACEDB FAQ --bks 


From owner-acedb@net.bio.net Tue Oct 24 22:00:00 1995
Path: biosci!GREENGENES.CIT.CORNELL.EDU!matthews
From: matthews@GREENGENES.CIT.CORNELL.EDU ("Dave Matthews")
Newsgroups: bionet.software.acedb
Subject: four Tablemaker questions/comments
Date: 25 Oct 1995 14:06:50 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 58
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9510252104.AA22344@greengenes.cit.cornell.edu>
NNTP-Posting-Host: net.bio.net

1. Is there any way to recover all the values of a tag that is defined as
REPEAT in the model?  E.g. all the ?Text's from

?Presence Present ?Text REPEAT // e.g. 14.5 6.6 4.4
          Absent ?Text REPEAT

Neither From nor Right_of in the table definition seems to work.  All I get
is the first value of each REPEAT series.


2.  It is possible to sort on multiple columns using the "Switch" button.
If column 3, for example, is switched into the first position, the whole
table is sorted on the column 3 values, thus:

Position(3) Map(2)              Locus(1)
0           Hordeum-NABGMP2-1H  aHor2       
0           Hordeum-NABGMP2-2H  MWG844      
0           Hordeum-NABGMP2-4H  WG622       
0.7         Hordeum-NABGMP2-7H  dRpg1       
0.8         Hordeum-NABGMP2-7H  Plc         
1.5         Hordeum-NABGMP2-6H  PSR167      
2.1         Hordeum-NABGMP2-7H  ABG077      
2.3         Hordeum-NABGMP2-2H  ABG058      
...

Then by switching column 2 into the first position, the values of column 3
remain sorted within each value of column 2:

Map(2)              Position(3) Locus(1)
Hordeum-NABGMP2-1H  0           aHor2       
Hordeum-NABGMP2-1H  11.1        Act8A       
Hordeum-NABGMP2-1H  81.1        MWG943      
Hordeum-NABGMP2-1H  93.3        His4A       
Hordeum-NABGMP2-1H  105.4       Dor3        
Hordeum-NABGMP2-1H  119.6       AtpB        
Hordeum-NABGMP2-1H  137.9       ABC261      
Hordeum-NABGMP2-1H  147         ABG710B     
Hordeum-NABGMP2-1H  159.3       MWG912      
Hordeum-NABGMP2-2H  0           MWG844      
Hordeum-NABGMP2-2H  2.3         ABG058      
Hordeum-NABGMP2-2H  5.4         WG516       
Hordeum-NABGMP2-2H  19.9        MWG682      
...

This "Switch" interface for specifying the column to sort on has been made
more intuitive in ace4_1.  There is now a field "Sort column" at the top of
the table definition window.  However the new interface doesn't work for
sorting on multiple columns:  setting the Sort column to 3, then to 2 leaves
column 3 scrambled again.  (The "Switch" routine still works.)


3.  In ace3-0 it was possible to ascii dump a table with the columns aligned
with Space characters, as in the examples above.  This was a really nice
feature.  I guess I should have said so while we had it, rather than waiting
to complain now that it seems to have disappeared.


4.  There are a lot of really nice features in the Tablemaker.

From owner-acedb@net.bio.net Tue Oct 24 22:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!EU.net!Germany.EU.net!news.dfn.de!news.ruhr-uni-bochum.de!news.rhrz.uni-bonn.de!hy
From: schmidt@nuklear.meb.unibonn.de (Herbert Schmidt)
Newsgroups: bionet.software.acedb
Subject: test
Date: 25 Oct 1995 16:19:05 GMT
Organization: Nuklear Medizin
Lines: 4
Message-ID: <46lo1p$n7p@news.rhrz.uni-bonn.de>
NNTP-Posting-Host: hy.meb.uni-bonn.de
Keywords: nothing
To: group
X-Newsreader: News Xpress Version 1.0 Beta #3

only a test
-+-+-+-+-+-+-

----hy----hy----hy----hy----

From owner-acedb@net.bio.net Tue Oct 24 22:00:00 1995
Path: biosci!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: about table maker
Date: 25 Oct 1995 22:59:50 -0000
Lines: 12
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <46mfh6$582@mserv1.dl.ac.uk>
Original-To: net@admcnrs.cnrs-mop.fr

I was told today that tace does not dump tables in exact alphabetic order
they are only listed correctly by chunks

it is easy to fix and will be available in next code
i think you can still ascii dump aligned tables by asking for tab
otherwise i ll fix that

the "Switch"  interface was passed into the command system by Suzy, merci, but
seems incomplete, i ll try top fix that too.

the condition on Text, which does not work in 4.1, will also be restored
sorry for all these bugs

From owner-acedb@net.bio.net Thu Oct 26 22:00:00 1995
Path: biosci!bcm.tmc.edu!cs.utexas.edu!usc!sdd.hp.com!col.hp.com!csn!magnus.acs.ohio-state.edu!lerc.nasa.gov!purdue!yuma!klab4.agsci.colostate.edu!user
From: martinf@lamar.colostate.edu (Martin L. Ferguson)
Newsgroups: bionet.software.acedb
Subject: Help: unable to leave 'Int' fields blank in .ace files
Date: Thu, 26 Oct 1995 16:54:37 -0600
Organization: Colorado State University
Lines: 26
Message-ID: <martinf-2610951654370001@klab4.agsci.colostate.edu>
NNTP-Posting-Host: klab4.agsci.colostate.edu

Greetings ACEDB users,

I am unable to leave 'Int' fields blank in a .ace file being read into
v4.1.  My model looks like this:

   ?SomeClass
      MyTag UNIQUE Int UNIQUE Int Text

In version 3, I could read an .ace file that looked like this:

   SomeClass : "name"
   MyTag "" "" "I only want to store text"

But in version 4, I get the following error:

   internal system error : parse error
   near line 27 in name : not an 
   integer after MyTag

Is there a way to leave an Int field blank?  Thanks.

-- 
Martin Ferguson                   martinf@lamar.colostate.edu
Dept. of Entomology               970-491-7989
CO State U.
Ft. Collins, CO  80523

From owner-acedb@net.bio.net Thu Oct 26 22:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!EU.net!Norway.EU.net!nntp-oslo.UNINETT.no!nntp-trd.UNINETT.no!daresbury!not-for-mail
From: mieg@kaa.crbm.cnrs-mop.fr (Danielle et Jean Thierry-Mieg)
Newsgroups: bionet.software.acedb
Subject: null int
Date: 27 Oct 1995 17:15:55 -0000
Lines: 19
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <46r44b$f8d@mserv1.dl.ac.uk>
Original-To: net@admcnrs.cnrs-mop.fr


Sorry, it was a bug of 3.1, you cannot have an empty field
in a line
use 0 0 or something like that or change the model

note that if you were to say:

   SomeClass : "name"
   MyTag "" "" "I only want to store text"

and later

   SomeClass : "name"
   MyTag 1 2

then "I only want to store text"
would be lost anyway

so the model is ackward

From owner-acedb@net.bio.net Sat Oct 28 22:00:00 1995
Path: biosci!mrc-lmb.cam.ac.uk!rd
From: rd@mrc-lmb.cam.ac.uk (Richard Durbin)
Newsgroups: bionet.software.acedb
Subject: Acedb data updates 4-9, 4-10, 4-11 for C.elegans
Date: 29 Oct 1995 11:00:47 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 97
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9510291854.AA03587@cele.mrc-lmb.cam.ac.uk>
NNTP-Posting-Host: net.bio.net


This is a broadcast message to the ACEDB mailing list and related
newsgroups.  If you are on the explicit mailing list and do not want
to be, please send email to rd@sanger.ac.uk.

ACEDB data updates 4-9, 4-10 and 4-11 for C. elegans
====================================================

It is nearly two months since update 4-8.  We are making three new
updates available at once to keep them a reasonable size.  These
should be used in conjunction with version 4_1 of the ACEDB program.
The total database size after adding updates 4-1 to 4-11 is
approximately 240 Mbytes.

The additions since 4-8 are:
  - more genomic sequence data (there are now 707 cosmids totalling
      21,762,318 bases).
  - over 12000 more cDNA EST sequences from Yuji Kohara, more than
      doubling the number available.  Thank you Yuji and colleagues.
  - Worm Breeders Gazette issue 14.1, plus some old missing abstracts
  - coordinate data for an embryonic lineage from Harald Hutter (most 
      cells up to 270mins, some up to 430 mins).  We plan to link 
      images to this data directly in a future version of acedb.  In the 
      mean time, we propose making TIFF images available packed up
      into timepoint-based ftp archives (700 images at 28 timepoints; 
      more details in a future email).
  - the new CGC subscribers list
  - various other new data, including more genetic and expression data.
  - a physical map update (October 13).
  - a number of errors and problems have been fixed -- in particular 
      a whole set of Df/Dup data were behaving incorrectly.

Macintosh version
=================

There will be a macace.4-11 shortly.  There will be a further broadcast
email message announcing this.

Instructions for obtaining updates/the whole thing
==================================================

All the files are available in the following public access accounts
(anonymous ftp sites) accessible over internet:

  ncbi.nlm.nih.gov (130.14.20.1) in the USA, in repository/acedb
  ftp.sanger.ac.uk in England, in pub/acedb
  lirmm.lirmm.fr (193.49.104.10) in France, in directory genome/acedb

In each case, log in as user "anonymous" and give a user identifier
as password.  Remember to transfer the files in BINARY mode by
typing the word "binary" at the start of your ftp session.  Many
thanks to NCBI for letting us share in their excellent resource.

Example:

ftp ncbi.nlm.nih.gov
login: anonymous
password: your user id or email address
cd repository/acedb             # change to relevant directoy
binary				# IMPORTANT
dir				# display files in this directory
get README
get NOTES
get INSTALL
cd ace4				# change to ace4 directory
get bin.sunos.4_1.tar.Z		# get program
cd ../celegans			# change to worm data directory
mget update*			# get all update files
quit

--------------------------------

Get any update.4-n.tar.Z that you do not have already and read the
file NOTES before proceeding further.

Always get a copy of the INSTALL script.  Move it and the .tar.Z files
into the home directory in which you are installing ACEDB.  Type
"source INSTALL".  Start acedb (normally by typing "acedb"), click
"Yes" to accept initialising the database if starting from scratch,
then choose "Add Update File" from the menu (right button), and press
"All updates" with the left mouse button.

If you have a problem making the program work, look at the section
on problems in NOTES, and if that fails to help, let us know.

******************************************************************

Comments about the data should be sent to the data curator, Sylvia
Martinelli (sylvia@sanger.ac.uk).

Comments about the program, or the installation procedure, should be
sent to one of us:

Richard Durbin (rd@sanger.ac.uk)
Jean Thierry-Mieg (mieg@kaa.cnrs-mop.fr)

-------------------- end of message --------------------

From owner-acedb@net.bio.net Sun Oct 29 22:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!lamarck.sura.net!sprout.nalusda.gov!usenet
From: JD Barnett <jbarnett@nalusda.gov>
Newsgroups: bionet.software.acedb
Subject: wwwace now available
Date: 30 Oct 1995 16:09:03 GMT
Organization: National Agricultural Library
Lines: 20
Message-ID: <472tav$6f@sprout.nalusda.gov>
NNTP-Posting-Host: phage.gig.usda.gov
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.1N (X11; I; SunOS 5.4 sun4m)
To: genome@locus.nalusda.gov
X-URL: news:bionet.software.acedb

wwwace provides a world wide web interface to ACeDB's graphical
displays. This package includes modifications to the ACeDB source code to
build wwwace, and the CGI scripts in perl to be run from the web. It is
designed for ACeDB version 4, to be run along with the text-based WWW
interface to ACeDB developed at NAL. 

The interface acts like xace with only the left button available. Only single
clicks can be passed back from a clickable image in an HTML document.
Thus, any right button actions (e.g., pop-up menus) or any drag operations
are not supported. (The only exception is the modification to the gmap
display to allow scrolling.) In wwwace as in xace, two clicks are required to
follow a link to another object on the display. 

wwwace can be downloaded at:  ftp://probe.nalusda.gov/pub/tools/wwwace.tar.gz

See http://probe.nalusda.gov:8000/acedocs/wwwace.html for more details, and
send questions or comments to gig@gig.usda.gov

-JD Barnett


From owner-acedb@net.bio.net Sun Oct 29 22:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!tank.news.pipex.net!pipex!lyra.csx.cam.ac.uk!news
From: pd@mole.bio.cam.ac.uk (Phil Davey)
Newsgroups: bionet.software.acedb
Subject: Changing from SIGMA to ACEDB?
Date: 30 Oct 1995 17:50:14 GMT
Organization: University of Cambridge, England
Lines: 9
Message-ID: <47338m$kup@lyra.csx.cam.ac.uk>
Reply-To: pd@mole.bio.cam.ac.uk
NNTP-Posting-Host: nab.path.cam.ac.uk

I have a database in SIGMA format, and I was wondering if anyone knows
how to change this format into one that either ACEDB or SAM can use.

Thanks very much for any help,
Phil
[E-mail pd@mole.bio.cam.ac.uk]




From owner-acedb@net.bio.net Mon Oct 30 22:00:00 1995
Path: biosci!agate!howland.reston.ans.net!newsfeed.internetmci.com!news.sesqui.net!oitnews.harvard.edu!purdue!yuma!klab4.agsci.colostate.edu!user
From: martinf@lamar.colostate.edu (Martin L. Ferguson)
Newsgroups: bionet.software.acedb
Subject: Need help with query syntax.
Date: Mon, 30 Oct 1995 15:51:34 -0600
Organization: Colorado State University
Lines: 13
Message-ID: <martinf-3010951551340001@klab4.agsci.colostate.edu>
NNTP-Posting-Host: klab4.agsci.colostate.edu

Hi all,

Is there a query which can be used with tace or aceserver/client which
will produce a listing of thoses classes which have greater than X number
of objects?  

Thanks,

-- 
Martin Ferguson                   martinf@lamar.colostate.edu
Dept. of Entomology               970-491-7989
CO State U.
Ft. Collins, CO  80523

From owner-acedb@net.bio.net Tue Oct 31 22:00:00 1995
Path: biosci!biosci!not-for-mail
From: staffan@biochem.kth.se (Staffan Bergh)
Newsgroups: bionet.announce,bionet.microbiology,bionet.software.acedb,sci.med
Subject: MycDB 4-9
Followup-To: bionet.microbiology
Date: 1 Nov 1995 13:23:19 -0800
Organization: Biochemistry, KTH, Stockholm
Lines: 112
Sender: biohelp@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: world
Message-ID: <478dal$gal@sibirien.physchem.kth.se>
NNTP-Posting-Host: net.bio.net
Keywords: MycDB, mycobacteria, ACEDB
Xref: biosci bionet.announce:2590 bionet.microbiology:3796 bionet.software.acedb:765 sci.med:99031

MycDB 4-9

Stockholm & Paris November 1, 1995

The ninth release of the Mycobacterium database, MycDB, is now available.

MycDB is funded by the WHO and the Fondation Raoul Follereau and is maintained
jointly by the Unite de Genetique Moleculaire Bacterienne at the Institut
Pasteur in Paris, France and the Department of Biochemistry at The Royal
Institute of Technology in Stockholm, Sweden.

MycDB is available free of charge via Internet network transfer. A complete
description of the procedure to retrieve and install the software and database
is available through the Internet.

MycDB is also available through the WorldWideWeb servers at the Royal Institute
of Technology (URL: http://www.biochem.kth.se/MycDB.html) and (through the good
offices of the Genome Informatics Group at the National Agricultural Library)
on the Agricultural Genome Information Server, AGIS, in Beltsville, Maryland,
USA (WorldWideWeb - URL: http://probe.nalusda.gov:8300/other/index.html or
gopher - URL: gopher://probe.nalusda.gov:7000/11/genome.databases/mycdb/). Be
aware that it may take some time for the update to reach NAL.

MycDB uses the excellent database software written by Richard Durbin (MCR-LMB,
UK) and Jean Thierry-Mieg (CNRS, France). The ACEDB software allows the user to
browse information by simply pointing and clicking with the workstation mouse.
A variety of powerful query methods are also available. However, our experience
is that most users choose the mouse interface to find the information they are
interested in.

As far as possible all information is connected to other information in the
database. The database software presents the information in separate windows
that allow many parts of the database to be viewed at one time. There are also
many paths to any piece of information, allowing the user to easily navigate
the connections between the various types of information.

New in release 4-9:

   *  We are now using version 4.1 of of the database manager, ACEDB. Versions
     exist for Unix/X11 and Macintosh. A complete package with the Macintosh
     application and a preloaded database is available. Update files for
     version 3.0 of the database manager are also available (this support will
     be discontinued in the near future). Ace 4.1 has the following new
     features:
        o  Less diskspace needed for the database (size is roughly halved -
          MycDB 4-9 takes about 25MB of diskspace, compared to 40MB for MycDB
          3-9).
        o  Faster display of large KeySets, due to presorting of keys.
        o  Blixem, the alignment display, is now fully integrated in AceDB.
          MycDB 4-9 contains blastn alignments for all sequences in MycDB
          against MycDB itself. With the correct external script, it will also
          fetch sequences not present in the database from an external source.
          A script for doing this is included, in the wscripts directory. At
          present, MycDb only contains blastp data for a few sequences.
        o  The Map display is now customizable to a great degree, both
          regarding the look and what objects to display.
        o  A new, WorldWideWeb-based, help system. This also requires an
          external script. The old help system is still there, as a backup.
   *  New and edited sequences from EMBL/GenBank/DDBJ, current as of Oct 30,
     1995. The number of Sequence objects is now 3234, of which 2891 are
     nucleotide sequences, and 343 Protein sequences. 591 of the nucleotide
     sequences contain DNA (the others are subsequences in some form or Peptide
     sequences). The total amount of sequence is now 2,238,856 nt, an increase
     of more than 43%. Most of this is due to the inclusion of a number of new
     cosmid sequences from M. leprae.
     Blastn searches have been performed on all the sequences in the database,
     against the complete database itself. This data is included. The data can
     be visualized with the Blixem tool.
   *  The number of literature citations have increased with 263. Included are
     citations from MedLine, current up to Oct 4, 1995. The references for
     sequences have been cleaned up to remove redundancies.
   *  The Locus class now includes some information on the function of the
     products. In the future this information will move to a new Protein class
     (for those products that are proteins).
   *  The webserver has a new sequence search facility, where you can make a
     blast search on all the sequences in MycDB or on strain-specific subsets
     for M.leprae, M.tuberculosis complex or M.smegmatis. The fasta files used
     for these searches are also available from the ftp site.

For information on earlier releases, see the file MycDB.3-8.Release.txt.

If you have any questions, problems or comments please contact us, via e-mail,
fax, mail or telephone. If you are impatient and are already familiar with
internet/ftp, all relevant information can be found at

   *  the WWW server at the Department of Biochemistry, KTH:
     http://www.biochem.kth.se/MycDB.html
   *  the ftp server at the Department of Biochemistry, KTH: ftp.biochem.kth.se
     (130.237.52.64) in pub/MycDB
   *  the ftp server at Institut Pasteur: ftp.pasteur.fr (157.99.64.12) in
     pub/MycDB
   *  or the mirror site at the Weizmann Institute in Israel (thanks Jaime!):
     bioinformatics.weizmann.ac.il (132.76.55.12) in pub/databases/acedb/mycdb

The file MycDB.Retrieval.txt describes in more detail the database system
requirements, network retrieval procedures for obtaining the database and
methods of obtaining future updates.

For more information contact Staffan Bergh or Stewart Cole.

Staffan Bergh
Biochemistry, Royal Institute of Technology, S-100 44 Stockholm, Sweden
Email: staffan@biochem.kth.se
Fax: (46 8) 24 54 52
Voice: (46 8) 790 9230

Stewart Cole
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, F-75724 Paris
Cedex 15, France
Email: stcole@pasteur.fr
Fax: (33 1) 45.68.85.93
Voice: (33 1) 45.68.84.46

From owner-acedb@net.bio.net Tue Oct 31 22:00:00 1995
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.software.acedb
Subject: IMPORTANT: BIOSCI miniFAQ
Date: 1 Nov 1995 02:03:29 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 196
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199511011000.CAA15134@net.bio.net>


This is a new "miniFAQ" designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

	Contents:
	--------
	1) What to do about "spams," i.e., junk mail, ads, etc.

	2) Examples of subscribing and unsubscribing to the mailing lists.

	3) How to access BIOSCI/bionet newsgroup archives.

	4) The BIOSCI user address and research interest directory.


1) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups)
and mailing lists.  The same postings are distributed on both media
(except for a small number of mailing-list-only groups at
net.bio.net).  Unfortunately it is becoming a despicable practice on
the Internet (by a few people out to make a fast buck) to do automated
mass postings to thousands of newsgroups and mailing lists.  These
attempts to grab free advertising are refered to as "spams" in the
usual, somewhat boneheaded, net terminology.  USENET is more
susceptible to this practice, and many spams originate on the USENET
groups and then are passed on to the mailing lists.  However, spammers
also get lists of mailing addresses and hit these too, so neither
medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the newsgroups from about 95% of the spams that
are being sent to date.  This means that someone has to take the time
to review each message before it goes out.  We have set up software
here that simply allows the moderator to forward to an address at
net.bio.net messages that (s)he wishes to have distributed.  This
takes no more time than that needed to read the message and pass it
on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings.
Unfortunately there are easy ways for determined spammers to override
the moderation mechanism.  We are working on new systems to provide
access to our newsgroups over the WWW.  These should be available
soon, probably November 1995, and will allow you to use your Web
browser to look at the news postings.  While this will not stop
spammers from trying to post to the groups, this will give you yet
another way, besides using USENET news, to keep the junk out of your
personal mail files.


2) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


3) How to access BIOSCI/bionet newsgroup archives.
--------------------------------------------------
Back postings of all BIOSCI/bionet newsgroups can be found on the
World Wide Web at URL http://www.bio.net/.  There are several
searchable newsgroup indices at this site.  E-mail users can search
the BIOSCI archives by using our waismail e-mail server.  For
instructions send the message

help

to waismail@net.bio.net.  Leave the Subject: line blank (anything
entered on the Subject: line is ignored).


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net

