From owner-acedb@net.bio.net Tue Sep 02 23:00:00 1997
Path: biosci!daresbury!not-for-mail
From: Danielle et jean Thierry-Mieg <mieg@kaa.crbm.cnrs-mop.fr>
Newsgroups: bionet.software.acedb
Subject: acedb release 4_5
Date: 3 Sep 1997 19:28:16 +0100
Lines: 158
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <5uka80$928@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk

This is a broadcast message to the ACEDB mailing list and related
newsgroups.  If you are on the explicit mailing list and do not want
to be, please send email to mieg@kaa.crbm.cnrs-mop.fr, rd@sanger.ac.uk.

ACEDB code release 4_5
======================

A new version of acedb is available at ncbi and the usual mirror sites
Ace 4_5 is fully compatible with ace.4_3, if you download this code,
you do not need to reconstruct your database.


New features
============

The overall quality of the code has been improved, the system is
faster and uses much less memory when exporting large relational
tables. The non graphic code has been extensivelly checked and
should be very reliable.

A number of graphics have changed, in particular the help system,
which now uses an http browser and the key-set display, which now
offers many submenus. There is a new Forest display, available from
the more-info button of the keyset window, which offers a custom view
of sets of objects, and a new Peptide display for proteins. Jo Dicks'
comparative map displays have been added.

Most other displays have been fixed and/or improved.  The sequence
display now offers asynchronous access to blast, biomotif and
oligo-search, via external calls using scripts in wscripts. The
genefinder options now have controllable parameters.  The blixem
display has many additions. The map display has several new
columns. The printer and file chooser are more flexible and easier to
control.  And so on.

Data curators should note the new file wspec/layout.wrm which
now controls wysiwyg the class layout of the main window.

Unix Binaries
=============

The distributed code has a subrelease letter, presently 4_5d/e, which
may continue to change a little while we build for more platforms, but
is irrelevant otherwise.  The code itself is now fixed.

Binaries are available for SUN, SOLARIS, Silicon, DEC, Linux; more
binaries will appear soon for IBM and HP, and since the source code is
available, you may also recompile for your platform if it is not on
this list.

Windows version
===============

For the fist time, we include a binary for windows-95 and windows-NT
intel machines. This code was prepared by Richard M. Bruskiewich, from
Vancouver from the same souce code. Please let us know of any problems
and also if you are happy with it. It seemed to be very fast on
pentium-200 machines.

To install winace, read the document WinAce.*.txt

Mac version
===========

Unfortunately, we are not able to port ace.4_5 for the mac. So the
last Mac version remains ace.4_1. We hope that Cyrus Hammon, who built
the current macace release will be able to recompile 4_5 for the mac,
or give us his latest source code, but there is no guarantee.  If you
are a mac programmer and would like to help, please let us know.

Server/Client
=============

Ace.4_5 server client capability have been substentially improved.
To gain space, and since any person installing a server is most probably
able to recompile, the servercode is not part of the binaries but must
be recompiled with the command: 
 make aceserver gifaceserver other

However, we do distribute the SOLARIS server, because the make command
on solaris produces an aceserver which does not work in daemon mode.
(help welcome if you are a solaris/rpc expert)

There is now a graphic client, xaceclient, with a start-up script
called xcl which will act exactly like xace, but getting its data
transparently form a remote server.

The gifaceserver can export postscript or gif files equivalent to the
standard graphic xace.  It will be used by the forthcoming revised
webace release.

The jade program can export the data to the Web using the recent java
language.


Instructions for obtaining updates/the whole thing
==================================================

All the files are available in the following public access accounts
(anonymous ftp sites) accessible over internet:

  ncbi.nlm.nih.gov (130.14.25.1) in the USA, in repository/acedb
  ftp.sanger.ac.uk in England, in pub/acedb
  lirmm.lirmm.fr (193.49.104.10) in France, in directory genome/acedb

In each case, log in as user "anonymous" and give a user identifier
as password.  Remember to transfer the files in BINARY mode by
typing the word "binary" at the start of your ftp session.  Many
thanks to NCBI for letting us share in their excellent resource.

Example:

ftp ncbi.nlm.nih.gov
login: anonymous
password: your user id or email address
cd repository/acedb             # change to relevant directoy
binary				# IMPORTANT
dir				# display files in this directory
get README
get NOTES
get INSTALL
cd ace4				# change to ace4 directory
get bin.xxx.4_5d.tar.Z		# get correct precompiled code
get source.4_5d.tar.Z           # and/or get the source code
quit

--------------------------------

If you want the C.elegans data, get any update.4-n.tar.Z that you do
not have already from the directory ../celegans.

Always get a copy of the INSTALL script.  Move it and the .tar.Z files
into the home directory in which you are installing ACEDB.  Type
"chmod 755 INSTALL ; INSTALL".  Start acedb (normally by typing
"acedb"), click "Yes" to accept initialising the database if starting
from scratch.  

If you imported the update files, choose "Add Update File" from the
menu (right button), and press "All updates" with the left mouse
button.

If you have a problem making the program work, look at the section
on problems in NOTES, and if that fails to help, let us know.

******************************************************************

Comments about the program, or the installation procedure, should be
sent to one of us:

Richard Durbin (rd@sanger.ac.uk)
Jean Thierry-Mieg (mieg@kaa.cnrs-mop.fr)

-------------------- end of message --------------------






From owner-acedb@net.bio.net Wed Sep 03 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!dispatch.news.demon.net!demon!delos.dra.hmg.gb!server1.netnews.ja.net!news.nott.ac.uk!usenet
From: mary anderson <arabidopsis@nottingham.ac.uk>
Newsgroups: bionet.software.acedb,bionet.plants
Subject: Opportunity for computational biologist, Uni. Nottingham, UK
Date: Thu, 04 Sep 1997 15:46:19 +0100
Organization: Cripps Computing Centre, The University of Nottingham
Message-ID: <340EC9BB.DC3D27CF@nottingham.ac.uk>
NNTP-Posting-Host: pplmax.nottingham.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.02 [en] (Win95; I)
Lines: 44
Xref: biosci bionet.software.acedb:1424 bionet.plants:16488

OPPORTUNITY FOR COMPUTATIONAL BIOLOGIST AT
NOTTINGHAM ARABIDOPSIS STOCK CENTRE,
THE UNIVERSITY OF NOTTINGHAM, UK

The Nottingham Arabidopsis Stock Centre (NASC) is an
international resource centre for seed resources and
information pertaining to the plant model system, Arabidopsis.
NASC has become the European touchstone for information
dissemination to the Arabidopsis research network through its
Stock Centre WWW server (URL=http://nasc.nott.ac.uk) and the
Arabidopsis Genome Resource (http://synteny.nott.ac.uk).

We are looking for a computational biologist to join the Stock Centre
to develop the current bioinformatics activities. Specific duties will
include the development of the in-house database for Stock Centre
administration, maintenance of the Stock Centre WWW server, and
some system administration.

The ideal candidate will have a PhD/MSc in molecular biology or
computer/information science. Non PhD/MSc candidates will also be
considered
if they have experience of computational biology or bioinformatics. The
candidate must also have experience of UNIX and some experience of
programming in C/Perl/Java would be beneficial.

The appointment is EU funded for 12 months (possibly extended to
16 months), and is available from 20th October 1997. Starting salary
will be flexible depending on experience.

For further details contact Mary Anderson (arabidopsis@nottingham.ac.uk)

Tel: 0115 9513237

To apply for this position please send a full cv and covering letter
including the names of two referees to
Dr Mary Anderson,
Nottingham Arabidopsis Stock Centre,
Dept of Life Science,
The University of Nottingham,
Nottingham, NG7 2RD, UK.

CLOSING DATE FOR APPLICATIONS IS 19th SEPTEMBER 1997,
INTERVIEWS WILL BE HELD ON THE 30TH SEPTEMBER/1ST OCTOBER.


From owner-acedb@net.bio.net Thu Sep 04 23:00:00 1997
Path: biosci!agate!howland.erols.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!server1.netnews.ja.net!server5.netnews.ja.net!daresbury!not-for-mail
From: Richard Durbin <rd@sanger.ac.uk>
Newsgroups: bionet.software.acedb
Subject: ACEDB data updates WS3.4-18 and 4-19
Date: 5 Sep 1997 10:29:55 +0100
Lines: 155
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <5uojej$8vs@mserv1.dl.ac.uk>
Original-To: acedb_distrib@sanger.ac.uk



This is a broadcast message to the ACEDB mailing list and related
newsgroups.  If you are on the explicit mailing list and do not want
to be, please send email to rd@sanger.ac.uk.

New ACEDB data release WG3.4-3 and WS3.4-18 and 19 for C. elegans 
=================================================================

IMPORTANT
=========
THE NEW DATA RELEASE CAN ONLY BE INSTALLED WITH NEW CODE VERSION 4_5,
WHICH HAS JUST BEEN RELEASED.

With this release we are still using the series of updates called
WS3 (and correspondingly WG3 for the version without sequences). If
you have not changed from WS2 to WS3, please get and read the
instructions in letter.may97 from the ftp directories.

The software has changed.  You should be using these updates in
conjunction with release 4_5 of the acedb software.  Instructions for
obtaining this are given below.  You will see changes in the main
window (classes displayed) and quite radical changes in the Keyset
window. Several other display windows have a new look, for example DNA
analysis and bibliography. The new layout on the main window will not
be fully realised until you have updated, saved, exited and re-opened
ACeDB.

Reminder: there are now two versions of the C.elegans database.  The
WS3 update series contains everything, whereas the WG3 update series
contains all data except sequences and directly related material
(proteins, motifs etc.), for those with limited resources.

The additions since the last release are:

for both types of update				

  - a physical map update  (mid July)
  - accumulated genetic data corrections
  - a re-build of the genetic maps after adding new map-data
     (submitted by end of april.)
  - from  CGC : bibliography, wbg subscribers and strains (July)
  - from Ian Hope's lab.: more expression patterns and many more images
  
and for just the complete database including sequences (WS3.4-18 to 19)

  Data fom St Louis and Sanger Sequence databases taken in mid-July:
  - There are now 2303 (2237 before) cosmids totalling 68938124 
     (66969575 before) bases.
  
The total database sizes after adding these updates are around 560MB
for the WS3 database and around 60MB for the WG3 database.

We apologise for the delay between finalising the data and
distribution for these updates, caused by delays in releasing the new
code version.

THE CELEGANS DIRECTORY
======================

This contains 3 additional directories in response to a request from
worm users: wscripts/, wspec.WS3.4-19/ and pictures/ .  The wscripts
directory has the executable script for viewing the expression images
and the pictures directory contains ALL images submitted to date. The
wspec.WS3.4-19/ directory has many changes which can only be used with
version 4-5 code.

All three have been bundled into the current update files and will
come automatically therefore to people who have taken copies of
updates.

Instructions for obtaining updates/the whole thing
==================================================

All the files are available in the following public access accounts
(anonymous ftp sites) accessible over internet:

  ncbi.nlm.nih.gov (130.14.20.1) in the USA, in repository/acedb
  ftp.sanger.ac.uk (193.60.84.11) in England, in pub/acedb
  lirmm.lirmm.fr (193.49.104.10) in France, in directory genome/acedb

In each case, log in as user "anonymous" and give a user identifier
as password.  Remember to transfer the files in BINARY mode by
typing the word "binary" at the start of your ftp session.  Many
thanks to NCBI for letting us share in their excellent resource.

Example:

ftp ncbi.nlm.nih.gov
login: anonymous
password: your user id or email address
cd repository/acedb             # change to relevant directoy
binary				# IMPORTANT
dir				# display files in this directory
get README
get NOTES
get INSTALL
cd ace4				# change to ace4 directory
get bin.solaris.4_5e.tar.Z	# get program (use relevant operating system)
cd ../celegans			# change to worm data directory
get update.WS3.4-18.tar.Z	# get relevant updates
get update.WS3.4-19.tar.Z	# or "mget update.WS3.*" to get all updates
quit

--------------------------------

Get any update files that you do not have already and read the file
NOTES before proceeding further.

Always get a copy of the INSTALL script.  Move it and the .tar.Z files
into the home directory in which you are installing ACEDB.  Type
"source INSTALL" (or if you are working with the bash shell in Linux,
type "csh INSTALL"). Start acedb (normally by typing "acedb"), click
"Yes" to accept initialising the database if starting from scratch,
then choose "Add Update File" from the menu (right button), and press
"All updates" with the left mouse button.

If you have a problem making the program work, look at the section
on problems in NOTES, and if that fails to help, let us know.

******************************************************************

Comments about the data should be sent to the data curator, Sylvia
Martinelli (sylvia@sanger.ac.uk).

Comments about the program, or the installation procedure, should be
sent to one of us:

Richard Durbin (rd@sanger.ac.uk)
Jean Thierry-Mieg (mieg@kaa.cnrs-mop.fr)

UPDATE FILE CONTENTS (BRIEFLY)

ws3.4-1 = geneace 1st half (i.e. non sequence material)
ws3.4-2 = geneace 2nd half (i.e. non sequence material)
ws3.4-3 = file1            (sequence_ace bits & pieces)
ws3.4-4 = peptide file

ws3.4-5 = dna1
ws3.4-6 = dna2
ws3.4-7 = dna3
ws3.4-8 = dna4
ws3.4-9 = dna5

ws3.4-10 = protein1
ws3.4-11 = protein2
ws3.4-12 = protein3

ws3.4-13 = sequence1
ws3.4-14 = sequence2 
ws3.4-15 = sequence3
ws3.4-16 = sequence4
ws3.4-17 = sequence5 & motif & general fixes

ws3.4-18 = non-sequence material
ws3.4-19 = corrections to sequence material.

From owner-acedb@net.bio.net Sat Sep 06 23:00:00 1997
From: planning@cyberpromo.com
Subject: Insurance Update
Newsgroups: bionet.software.acedb
Organization: Advanced Planning Solutions
NNTP-Posting-Host: 207.99.47.138
Message-ID: <341229b7.0@nntp1.nac.net>
Date: 7 Sep 97 04:12:39 GMT
Lines: 35
Path: biosci!bloom-beacon.mit.edu!eru.mt.luth.se!feed1.news.erols.com!news.maxwell.syr.edu!nac!nntp1.nac.net!207.99.47.138




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From owner-acedb@net.bio.net Tue Sep 09 23:00:00 1997
Path: biosci!OCTOGENE.MEDGEN.UBC.CA!rbrusk
From: rbrusk@OCTOGENE.MEDGEN.UBC.CA (Richard Bruskiewich)
Newsgroups: bionet.software.acedb
Subject: Re: WinAce97: ACEDB for Windows - August 9th Release Advisory
Date: 10 Sep 1997 07:58:10 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 83
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <Pine.SOL.3.94.970910071224.14152A-100000@octogene>
Reply-To: Richard Bruskiewich <rbrusk@octogene.medgen.ubc.ca>
NNTP-Posting-Host: net.bio.net

This posting pertains to the INITIAL August 9th, 1997 post-ACEDB '97
release of WinAce97 (ACEDB for Windows).  Subsequent releases (after
this date, i.e. August 15th and beyond) do not cause the installation
problem described in this advisory. NOTE: The NCBI mirror of the Sanger
ftp copy of winace97 was somewhat delayed in being updated. The newer
release had a README.WINDOWS file but is, unfortunately, the archive
name was not originally timestamped (except through the filing system,
with a later Sept 3, 1997 file date). This latter problem is now resolved:
the re-release is named "winace97_Aug15.zip".

The release (packaged as a .zip archive) is in a new "InstallShield" based
format which gives Windows users their familiar "setup.exe" functionality
seen with most commercial installations of programs.

Unfortunately, this initial installation was inadvertently designed to
generously provide winace users with (NT default) copies of certain MS
Windows dynamic linked libraries (DLL's):

	wsock32.dll
	ws2_32.dll
	ws2help.dll

which are now known to be
standard upon (most) Windows systems.  Since the InstallShield utility (at
least, the "Visual C/C++ 4.2 Express" version used to generate the
winace archive) does not complain about overwriting existing
files, users with non-default versions of the Windows DLL's would see
newer, non-default versions of the files quietly overwritten.

The overwriting of the ws2*.dll did not appear to be the problem.
The biggest culprit is wsock32.dll (found under the windows\system (for
Windows '95) or winnt\system32 (for NT) subdirectory) for which some users
have sophisticated enhanced versions for increased internet (e.g.
netscape, ping, ftp, etc.) service functionality.

IF YOU HAVE BEEN ENCOUNTERING INTERNET PROBLEMS SINCE INSTALLING WINACE,
THIS IS THE LIKELY (AND TO MY KNOWLEDGE, ONLY) CULPRIT.

First, if you are among this small (but important) group of winace
pioneers (with the arrows in your back), I offer my sincerest apologies
for the anguish caused by this installation bug.

Second, I offer the following bug fix advisory:

1.	You DON'T need to download the August 15th version of Winace
because all it does is fix the installation so that the above bug does not
occur (wsock32.dll is not overwritten).

2a.	If you have a copy of YOUR custom wsock32.dll (i.e. you backed up
windows\system (for Windows '95) or winnt\system32 after installing your
increased internet functionality but before installing winace) then just
restore that copy.

OR

2b.	If you don't have a backup of wsock32.dll, then try reinstalling
your particular internet software (e.g. netscape, ping, ftp, etc.).

If none of the above works, please contact me (at
rbrusk@octogene.medgen.ubc.ca) with a description of your particular
operating configuration (OS, network items installed, etc.) so we can work
together to fix the problem.

Once again, my sincerest apologies for this unexpected installation
problem.

Richard M. Bruskiewich

Wood Lab, Dept. of Medical Genetics
Faculty of Medicine
University of British Columbia
318 - 6174 University Blvd
Vancouver, BC
V6T 1Z3

E-Mail:	rbrusk@octogene.medgen.ubc.ca
WWW:    http://mendel.medgen.ubc.ca/rbrusk/RichardB.html
Tel:	(604) 822-6830
Fax:	(604) 822-5348





From owner-acedb@net.bio.net Sat Sep 13 23:00:00 1997
Path: biosci!bloom-beacon.mit.edu!ai-lab!netnews.com!europa.clark.net!204.127.161.1!wnfeed!worldnet.att.net!205.252.116.205!howland.erols.net!nntp2.crl.com!news7.crl.com!news.west-tech.com!clark.a43.smsu.edu
From: info@pgrs.com
Newsgroups: bionet.software.acedb
Subject: WANT A FREE PAGER? LOOK HERE!
Date: 13 Sep 97 22:08:43 GMT
Organization: PAGERS
Lines: 38
Message-ID: <341b0eeb.0@news.west-tech.com>
NNTP-Posting-Host: 165.113.201.24


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From owner-acedb@net.bio.net Wed Sep 17 23:00:00 1997
Path: biosci!agate!ihnp4.ucsd.edu!munnari.OZ.AU!news.mel.connect.com.au!news.syd.connect.com.au!not-for-mail
From: teems@lateral.com.au
Newsgroups: bionet.software.acedb
Subject: NEW ONLINE TECHNOLOGY TRADING FLOOR
Date: 18 Sep 1997 02:40:33 GMT
Organization: Customer of Connect.com.au P/L, Sydney, Australia
Lines: 33
Message-ID: <5vq4b1$ch$2@merki.connect.com.au>
NNTP-Posting-Host: 203.63.105.1

Hi,

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From owner-acedb@net.bio.net Sat Sep 20 23:00:00 1997
Date: Sun, 21 Sep 1997 03:47:16
From: Me
Newsgroups: bionet.software.acedb
Subject: Information
NNTP-Posting-Host: sd-ppp-103.abac.com
Message-ID: <3424fba2.4@news1.abac.com>
Lines: 24
Path: biosci!rutgers!news.cis.ohio-state.edu!nntp.sei.cmu.edu!nntp.club.cc.cmu.edu!eecs-usenet-02.mit.edu!netnews.com!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.internetmci.com!208.137.248.9!news1.abac.com!sd-ppp-103.abac.com

Hello
	You don't know me and I would understand if you went ahead and just deleted this note without reading it. Just like you I'm not crazy about getting mail from someone I don't know.

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************

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From owner-acedb@net.bio.net Tue Sep 23 23:00:00 1997
Path: biosci!OWLSNEST.COM!owl
From: owl@OWLSNEST.COM
Newsgroups: bionet.software.acedb
Subject: Is Your Web Site A Secret?
Date: 23 Sep 1997 19:11:47 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 131
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199709240155.VAA08225@owlsnest.com>
Reply-To: owl@owlsnest.com
NNTP-Posting-Host: net.bio.net

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much faster.

WHAT SEARCH ENGINES AND INDEXES ARE INCLUDED IN THE
PROMOTION?

The list changes from time to time.  This is our current list:

Abaweb!, Alta Vista, Been There, BizWeb, Central Source Yellow Pages,
Enterpreneurs on the Web, Excite, Four11, Galaxy, I-Network I-Systems
Spiral Business Directory, I-World Web Pointer, Infoseek, Inktomi,
Innovator's Network Yellow Pages, Internet Mall, Jayde Online Directory,
Jumpcity, Jumper Hot Links, Linkmaster, Lycos, Magellan, Mega Mall,
Net-Happenings, Net Navigator, Net Mall, NTG's List, NYNEX Big Yellow,
One World Plaza, OnLine's WWWeb Index, Rex, Starting Point, Truenorth,
URL Tree, Virtual Lynx, Web Point, WebCentral, Web Venture Hotlist,
Webcrawler, Websurf, Win Mag/NetGuide Hotspots, WhatUSeek, Worldwide
Announce Archive, WWW Business Yellow Pages, World Wide Yellow Pages,
WWW Worm, YelloWWWeb.


HOW WILL I KNOW THAT YOU HAVE PROMOTED MY SITE?

When we have completed the promotion, we will send you an HTML
file as an attachment to your E-mail bill.  Save this file to your
disk, and view it through your Web browser.  It provides links to the
search engine we submitted your site to, plus any comments we received
from them when we did it.

ARE THERE ANY GUARANTEES?

We do not require prepayment.  Your satisfaction is guaranteed or
you don't pay the bill.

WHO IS OWL'S EYE PRODUCTIONS?

We are a web site promotion company located at:

   Owl's Eye Productions, Inc.
   260 E. Main Street
   Brewster, NY 10509
   Phone: (914) 278-4933
   Fax:     (914) 278-4507
   Email: owl@owlsnest.com


HOW DO I ORDER?

The easiest way to order is by e-mail.  Just hit the REPLY button on
your e-mail program and fill out the following information. (This
information will be posted to the search engines/indexes):

Your name: 
Company Name:
Address:
City:              State/Prov:     Zip/Postal Code: 
Telephone: 
Fax: 
Email address: 
URL:  http://
Site Title: 
Description (about 25 words): 
Key words (maximum of 25, in descending order of importance):

Proofs (Where shall we e-mail proofs): 

If  billing a different address, please complete the following:

Addressee: 
Company Name:
Address:
City:              State/Prov:     Zip/Postal Code: 
Telephone: 
Fax: 
Email address: 

We will bill via Email. (7519)

Terms:  By returning this document via Email, you agree as follows:
You have the authority to purchase this service on behalf of your
company.    Terms are net 15 days.  Accounts sent to collections will
be liable for collection costs.  You agree to protect and indemnify
Owl's Eye Productions, Inc. in any claim for libel, copyright
violations, plagiarism, or privacy and other suits or claims based on
the content or subject matter of  your site.

WHAT HAPPENS NEXT?

When we receive your order, we will input the information into
our system, and send you a proof.

After we process any corrections, we will run your promotion, capturing
any comments from search engines as we go.  We will incorporate these
into an HTML-formatted report to you, which we will attach to
your bill.
===Web Promotions=====Press Releases=====Link Exchanges=========
                 Owl's Eye Productions, Inc.
                   260 E. Main Street
                   Brewster, NY 10509
Ph: 914-278-4933  Fx: 914-278-4507  E-mail: owlseye@owlsnest.com

From owner-acedb@net.bio.net Wed Sep 24 23:00:00 1997
Path: biosci!MPI.COM!das
From: das@MPI.COM (Sudeshna Das)
Newsgroups: bionet.software.acedb
Subject: acedb release 4_5
Date: 25 Sep 1997 12:18:47 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 10
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <3.0.32.19970925151524.007121e0@mail.mpi.com>
NNTP-Posting-Host: net.bio.net

Hi,

In the previous release 4_3 I could view the results of blastx as three
separate columns for the hits to the three frames of translation. In the
current release all the hits appear to be clubbed in one column. 
Is there any parameter that I can set during installation or anything else
I can do to get the three frame to show in three columns?

Thanks
sudeshna

From owner-acedb@net.bio.net Wed Sep 24 23:00:00 1997
Path: biosci!agate!howland.erols.net!newsfeed.direct.ca!newshub1.home.com!news.home.com!news.rdc1.md.home.com!cc404921-a.twsn1.md.home.com!user
From: Webmaster@scienceguide.com (Robert W. Georgantas III)
Newsgroups: bionet.software.acedb
Subject: BioScience Information
Date: 25 Sep 1997 07:57:45 GMT
Organization: The Science Guide
Lines: 65
Message-ID: <Webmaster-2509970400000001@cc404921-a.twsn1.md.home.com>
Reply-To: news@scienceguide.com
NNTP-Posting-Host: cc404921-a.twsn1.md.home.com

Announcing the SCIENCE GUIDE.
http://www.scienceguide.com

A New Internet Directory and Information Service run by Scientists and
Physicians for Scientists and Physicians.  After visiting the Guide, If
you have any suggestion for making the Guide better please let us know.
(webmaster@scienceguide.com)

The Science Guide consists of a number of different sections designed to
help the scientist and physician find information on the internet and to
sponsor communication between those interested in science:


NEWS SECTION

Every day the Science Guide compiles medical and research news from
national news sources around the net.  Most of the news articles are
concerned with medicine, bioscience, and physics, but all other sciences
from agriculture to zoology are commonly included. News sources currently
listed include: CNN, EurekAlert, HMS Beagle, MSNBC Sci-Tech, Science
Magazine¹s ScienceNow, CBS Space News, USA Today, The Albuquerque Journal,
Scientific American Web Weekly, The Why Files, Discover Magazine,
Scientific American, Smithsonian Magazine, and the Technology Review.  The
news pages also list links to news sources not compiled within the News
site.  We are currently working on adding a number of other sources to the
site to make it even more useful.

To make getting science news even easier, we send out a DAILY NEWS EMAILER
listing the articles which have been compiled on our site.  Anyone can
subscribe to the Emailer by sending an email to news@scienceguide.com with
the message ³Subscribe²


DIRECTORY OF USENET NEWS GROUPS and DISCUSSION LISTS

The Directory of Usenet and Discussion Groups is compiled quarterly from
different sources around the net to provide the scientist and those
interested in science easy access to these invaluable sources of discourse
and information.  We are currently working on finding the proper
subscription method for each of the discussion lists.  This is taking a
bit longer that we thought so please pardon our dust.  The Usenet portions
of this section are complete.


ON-LINE JOURNAL HYPERLINK SECTION

The Journals Section contains links to peer reviewed scientific journals
on the Internet.  Each listing clearly indicates whether the journal
provides only the table of contents, TOC with abstracts, or the full text
of the journal


EMPLOYMENT SECTION

The Jobs and Positions Section contains hyperlinks to the best Scientific
Employment Databases and Classifieds on the net.


GRANTS and FUNDING SECTION

The funding section contains links to the best funding and grant databases
on the Internet, making it very easy for scientists to quickly find
funding opportunities.  The featured site of the section is ³The Community
of Science,² a Johns Hopkins service designed to help scientists find and
continue funding.

From owner-acedb@net.bio.net Wed Sep 24 23:00:00 1997
Path: biosci!NET.BIO.NET!biosci-help
From: biosci-help@NET.BIO.NET (BIOSCI Administrator)
Newsgroups: bionet.software.acedb
Subject: Spam moderation for ACEDB newsgroup
Date: 25 Sep 1997 16:25:58 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 142
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <CMM-RU.1.4.875229955.biohelp@net.bio.net>
Reply-To: biosci-help@net.bio.net
NNTP-Posting-Host: net.bio.net

As you may have seen in an earlier posting, we will soon implement a
new policy to control spam in unmoderated groups. The original message
is copied directly below.  Appended after it is a copy of my proposed
new group charter, which is minimally different from the current one.
If you have any suggestions for change in the text or in the policy,
please let me or the group know within the next week or so.

Thanks,
Serge Taylor
Biosci Administrator
Stanford University

============== original message ==============================

As part of our effort to eliminate "spam" messages which are offensive
and distracting to the scientific discussions which the Biosci
newsgroups are designed to facilitate, we are creating a new type of
moderated newsgroup -- "Moderated (only to filter out spam)".

Our rationalie is that only what usenet recognizes as "moderated"
newsgroups can filter mail postings, yet it has proven difficult to
find volunteer moderators from each newsgroup.

Our intention is to use a combination of human and software filters to
eliminate the most egregious examples of spam. Since we value
diversity of opinion in scientific communications, and recognize that
our efforts are unavoidably subject to both Type I and Type II errors,
we aim to err on the side of allowing arguably scientifically relevant
communications to be posted. 

We intend to convert all the unmoderated bionet newsgroups to the new
status as soon as possible, and forsee two situations:

(1) Where a charter exists for an established but unmoderated group,
we will take the current charter and add the following language (taken
>From the policy statement which we send to anyone who wishes to start
a new newsgroup or convert an unmoderated to moderated newsgroup, and
suitably customized to the newsgroup where necessary) on "Moderation
Policy":

"Moderation Policy: Mass-posted commercial messages, chain letters,
and similar postings not germane to the stated purpose of the charter
will be deleted without comment. Inappropriate messages posted in good
faith will be returned to the sender where feasible.  Messages not
strictly within the charter but likely to be of interest to many
subscribers will be accepted.  Use of the newsgroup for commercial
purposes is prohibited."

The proposed new charter will be posted to the newsgroup for a short
comment period.


(2) Where a charter does not exist for an established unmoderated
group, we will solicit the newsgroup's discussion leader(s), where
listed, to draft a non-controversial charter and submit it to the
newsgroup for a short comment period.


If at any time a moderated-for-spam newsgroup wishes to convert to a
regular "moderated" group, with its own moderator, we shall be happy
to treat such a request just as we do the request to change from
unmoderated to moderated status.

Finally, if a currently moderated group wishes to take advantage of
the spam filtering software to ease the administrative burden on the
moderator, we will discuss the logistics and policy guidelines with
the group's moderator. (We will notify moderators when we are ready to
offer this facility; we are not currently ready.)

We hope that these new arrangements will protect the integrity of our
newsgroups and allow us to focus on other ways of improving Biosci.

Thank you for your patience and understanding as we deal with the spam
problem.

Serge Taylor
Biosci Administrator
Stanford University Libraries


========== proposed modified charter ====================

Charter for ACEDB-SOFT/bionet.software.acedb

Moderation Status: Moderated for spam

E-mail addresses: acedb@net.bio.net
                  acedb@daresbury.ac.uk

Discussion leader:  Mike Cherry
                    Director of Computing
                    Department of Molecular Biology
                    Massachusetts General Hospital
                    Boston, MA  02114

                    Voice: 617-726-5955
                    FAX:   617-726-6893

                    Internet:  cherry@frodo.mgh.harvard.edu


Charter ACEDB-SOFT/bionet.software.acedb:

Discussions by users and developers of genome databases using the
ACEDB software.

This group includes discussions ranging from construction of new
databases using the ACEDB software, curation of genetic and physical
map information into Ace format, to questions about the use of any of
the species specific databases utilizing the ACEDB software.

As part of the C. elegans genome effort Jean Thierry-Mieg and Richard
Durbin developed a generalized software solution for genome databases.
ACEDB is the name of the software used for the organization,
presentation and storage of genome information. It is also the name of
the first database to use this software, the the C. elegans genome
database. ACEDB includes an X-windows user interface and an
object-like database engine developed specifically for storage of
biological information.

Many groups have begun using ACEDB to create a variety of genome
databases. As of April 1993 three of these groups have released their
databases to the general public and many others are well along in
their development. The number of groups utilizing the ACEDB software
to organize, manipulate and disseminate genome information is
increasing. An informal community of ACEDB developers has formed to
share knowledge and resources. This group allows the community of
developers and users to continue sharing and growing. The archives of
the group also provide a useful resource to both developers and users.

Moderation policy: (added 25 September 1997)

This newsgroup is moderated by automatic spam filtering software and
by Biosci personnel to implement the following policy:

Mass-posted commercial messages, chain letters, and similar postings
not germane to the stated purpose of the charter will be deleted
without comment. Inappropriate messages posted in good faith will be
returned to the sender where feasible.  Messages not strictly within
the charter but likely to be of interest to many subscribers will be
accepted.  Use of the newsgroup for commercial purposes is prohibited.


From owner-acedb@net.bio.net Wed Sep 24 23:00:00 1997
Path: biosci!agate!howland.erols.net!newsfeed.internetmci.com!192.220.251.22!netnews.nwnet.net!news-hub.interserv.net!news.interserv.com!email-now4.com
From: "URGENT !!!" email97@email-now4.com
Newsgroups: bionet.software.acedb
Subject: >>> F R E E    V A C A T I O N S <<<
Date: Thu, 25 Sep 1997 19:13:43 -0700
Organization: VWX
Lines: 89
Message-ID: <250997191343@email-now4.com>
NNTP-Posting-Host: dd05-125.dub.compuserve.com

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From owner-acedb@net.bio.net Thu Sep 25 23:00:00 1997
Path: biosci!daresbury!not-for-mail
From: Danielle et jean Thierry-Mieg <mieg@kaa.crbm.cnrs-mop.fr>
Newsgroups: bionet.software.acedb
Subject: blast hit display
Date: 26 Sep 1997 09:30:43 +0100
Lines: 14
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <60frrj$kem@mserv1.dl.ac.uk>
Original-To: acedb@dl.ac.uk


In the previous release 4_3 I could view the results of blastx as three
separate columns for the hits to the three frames of translation. In the
current release all the hits appear to be clubbed in one column.

Notice also that in the current version the hits on the 2 starnds
appear now on the 2 sides of the yellow bar and scale

to separate them in 3 columns, press the genefinder button
these 2 things are linked may be they should be separated
the notion is that it is interesting to see the actual frame only in as much as
you also look at the stop codons etc.

jean

From owner-acedb@net.bio.net Fri Sep 26 23:00:00 1997
Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!newsfeed.ecrc.net!newshub2.home.com!news.home.com!howland.erols.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!gatech!138.26.64.6.MISMATCH!news.cis.uab.edu!news.lsu.edu!news.msy.bellsouth.net!news.mem.bellsouth.net!news.clt.bellsouth.net!news.mco.bellsouth.net!not-for-mail
From: ATTRACT MORE WOMEN<hiert@star.com>
Newsgroups: bionet.software.acedb
Subject: HOW TO ATTRACT GIRLS  INSTANTLY....Secrets to instant sex appeal!!!
Date: 27 Sep 1997 11:31:51 GMT
Organization: ATTRACT MORE WOMEN
Lines: 153
Message-ID: <60iqr7$eot$1844@news.mco.bellsouth.net>
NNTP-Posting-Host: d00058.mco.bellsouth.net

 HOW TO ATTRACT GIRLS  INSTANTLY....Secrets to instant sex appeal

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From owner-acedb@net.bio.net Sat Sep 27 23:00:00 1997
Path: biosci!rutgers!gatech!4.1.16.34.MISMATCH!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!News1.Ottawa.iSTAR.net!News1.Toronto.iSTAR.net!news.istar.net!tor-nx1.netcom.ca!news.securenet.net!not-for-mail
From: lohwxt@112233.com (lupxnu)
Newsgroups: bionet.software,bionet.software.acedb
Subject: Where's the snow? - 333.gif [1/1]
Date: 28 Sep 1997 20:29:43 GMT
Organization: Interyellow
Lines: 211
Message-ID: <60menn$t3k$310@news.securenet.net>
NNTP-Posting-Host: client68.securenet.net
Mime-Version: 1.0
Content-Type: multipart/mixed;
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Xref: biosci bionet.software:19628 bionet.software.acedb:1450

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Have you been good this year???????????

What do you want for Christmas?
      http://www.santas.com
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--*- Boundary ac2---


From owner-acedb@net.bio.net Sun Sep 28 23:00:00 1997
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From: "Max" <manmax@hotmail.com>
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From owner-acedb@net.bio.net Tue Sep 30 23:00:00 1997
Path: biosci!agate!overload.lbl.gov!acedbfaq
From: acedbfaq@s27w007.pswfs.gov (ACEDB FAQ Curator)
Newsgroups: bionet.software.acedb,news.answers
Subject: ACEDB Genome Database Software FAQ
Followup-To: bionet.software.acedb
Date: 1 Oct 1997 17:48:25 GMT
Organization: Dept. Plant Breeding, Cornell University
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Approved: news-answers-request@MIT.Edu
Distribution: world
Message-ID: <60u2d9$mci@overload.lbl.gov>
Reply-To: acedbfaq@s27w007.pswfs.gov
NNTP-Posting-Host: s27w007.pswfs.gov
Summary: Frequently Asked Questions about finding and getting started with the genome database software ACEDB.

URL: http://probe.nalusda.gov:8000/acedocs/acedbfaq.html
Archive-name: acedb-faq
Last-modified: 1 Oct 97
Version: 1.39

----------------------------------------------------------------------------

ACEDB FAQ

----------------------------------------------------------------------------
Curated by: Dave Matthews
----------------------------------------------------------------------------

Frequently Asked Questions about ACEDB

   * Q0 : What is ACEDB?
   * Q1 : ! What is the current version of ACEDB?
   * Q1.5 : + What's new in ACEDB 4_5?
   * Q2 : Where can I get ACEDB?
   * Q3 : ! What hardware/software do I need to run ACEDB?
   * Q4 : Can ACEDB be networked?
   * Q5 : What documentation exists for ACEDB?
   * Q6 : What newsgroups and mailing lists are available for ACEDB?
   * Q7 : Is there a repository of software tools for ACEDB curators?
   * Q8 : When and where is the next ACEDB Workshop?
   * Q9 : How does ACEDB compare to commercial relational DBMS's?
   * Q10 : How should ACEDB be cited?
   * Q11 : What ACEDB databases exist?
   * Q12 : Who prepared this document & where is the current version?

Questions marked with '+' are new, those with '!' have substantially changed
answers.
----------------------------------------------------------------------------

Q0: What is ACEDB?

A0:

ACEDB is an acronym for A Caenorhabditis elegans Database. It can refer to a
database and data concerning the nematode C. elegans, or to the database
software alone. This document is concerned primarily with the latter
meaning. ACEDB is being adapted by many groups to organize molecular biology
data about the genomes of diverse species.

ACEDB allows for automatic cross-referencing of items during loading and
allows for hypertextual navigation of the links using a graphical user
interface and mouse. Certain special purpose graphical displays have been
integrated into the software. These reflect the needs of molecular
biologists in constructing genetic and physical maps of genomes.

ACEDB was written and developed by Richard Durbin (MRC LMB Cambridge,
England) and Jean Thierry-Mieg (CNRS, Montpellier, France), beginning in
1989. It is written in the C programming language and uses the X11 windowing
system to provide a platform independent graphical user interface. The
source code is publicly available. Durbin & Thierry-Mieg continue to develop
the system, with contributions from other groups.

A description by Durbin & Thierry-Mieg: ACEDB does not use an underlying
relational database schema, but a system we wrote ourselves in which data
are stored in objects that belong in classes. This is nevertheless a general
database management system using caches, session control, and a powerful
query language. Typical objects are clones, genes, alleles, papers,
sequences, etc. Each object is stored as a tree, following a hierarchical
structure for the class (called the "model"). Maps are derived from data
stored in tree objects, but precomputed and stored as tables for efficiency.
The system of models allows flexibility and efficiency of storage --missing
data are not stored. A major advantage is that the models can be extended
and refined without invalidating an existing database. Comments can be added
to any node of an object.

Return to List of Questions
----------------------------------------------------------------------------

Q1: What is the current version of the ACEDB software?

A1:

The current Unix version is ace.4_5d/e, released 28 August 1997.

Enhancements added during the ACE97 Workshop will be incorporated in the
next release.

The very latest development version is always available at
ftp://ftp.sanger.ac.uk/pub/acedb_src/. This is unsupported and not to be
redistributed.

The Windows 95/NT version 4.5.2, 15 August 1997, corresponds to Unix
test.ace.4_5c. For current information see the WinAce Web page at
http://mendel.medgen.ubc.ca/rbrusk/winace.html.

A Macintosh version is available as version 4.1b1, August 1995.

Return to List of Questions
----------------------------------------------------------------------------

Q1.5: What's new in ACEDB 4_5?

A1.5:

At present, all documentation on new ace4_5 features is in the Proceedings
of the ACE97 workshop.

Return to List of Questions
----------------------------------------------------------------------------

Q2: Where can I get ACEDB?

A2:

Source code and Unix binaries are available in the following anonymous ftp
sites:

   * ncbi.nlm.nih.gov in repository/acedb
   * ftp.sanger.ac.uk in pub/acedb
   * lirmm.lirmm.fr in pub/acedb
   * bioinformatics.weizmann.ac.il in pub/databases/acedb

Linux binaries in ELF and a.out format, from Jeff Bryer:

   * ncbi.nlm.nih.gov in repository/acedb
   * bioinformatics.weizmann.ac.il in pub/databases/acedb

NEC EWS4800 binaries:

   * http://www.labs.nec.co.jp/freesoft/freesofte.html

Windows 95/NT 3.51, from Richard Bruskiewich:

   * ftp.sanger.ac.uk in pub/winace
   * bioinformatics.weizmann.ac.il in pub/databases/acedb
   * Documentation: http://mendel.medgen.ubc.ca/rbrusk/winace.html

MacAce, from Frank Eeckman, Cyrus Harmon and Richard Durbin:
(Note: The authors are not currently able to support MacAce. Latest version
was 4.1b1.)

   * genome.lbl.gov in pub/macace
   * ncbi.nlm.nih.gov in repository/acedb/macace
   * bioinformatics.weizmann.ac.il in pub/databases/acedb

Return to List of Questions
----------------------------------------------------------------------------

Q3: What hardware/software do I need to run ACEDB?

A3:

The software is available in binary (pre-compiled) format for a variety of
machines.

   * Unix:
        o Sun/SunOS 4.x
        o Sun/Solaris
        o DEC DECstation3100, 5100 etc.
        o DEC Alpha/OSF-1
        o Silicon Graphics Iris series 4, 5, 6
        o IBM RS-6000
        o PC 386/486/Pentium with Linux
        o NEC EWS4800
        o NeXT: contact Patrick Phillips at University of Texas, NeXTmail:
          patrick@wbar.uta.edu email: phil@decster.uta.edu
        o There exist, or have existed, ports onto Alliant, Hewlett-
          Packard, Convex. You may have to contact the developer responsible
          for the port to make these real.
   * Windows 95/NT
   * Macintosh (not currently supported)

The software is also available as source code, so you may be able to get it
working on any machine.

Memory requirements (from Richard Durbin, aug 97)

The amount of memory you require for ACEDB depends very much on how big the
database is (i.e. the disk space used by the database/ subdirectory). Our
rule of thumb is that one typically uses 5-10Mb plus up to 10% of the disk
space size of the database. So with a 200Mb database perhaps 25Mb memory,
and with a 500Mb database (e.g. the C. elegans one) up to 50-60Mb. In fact
for short sessions less memory is used -- it is only when all classes are
explored, or for example when parsing big files that these amounts of memory
get used.

Return to List of Questions
----------------------------------------------------------------------------

Q4: Can ACEDB be networked?

A4:

ACEDB Client / Server Computing (from Doug Bigwood, aug97)

There are several client/server models for ACEDB computing and several more
are in development. The start of the ACEDB client/server age began with the
inclusion of aceclient and aceserver in version 4.0. These are C - based and
use the RPC protocol for communication. These executables can be made from
the standard ACEDB distributions.

Starting in version 4.5 an xaceclient is also included with ACEDB.
Xaceclient provides remote read/write access to an aceserver while providing
the user with the same X displays that are found in xace. To use it, you
create an empty database with the appropriate models and start xaceclient.
It will automatically retrieve data from the server declared in
wspec/server.wrm (the Montpellier server in the distribution server.wrm).
The data will be saved locally and can then be viewed with a normal xace.

A perl extension which provides aceclient functionality to Perl 5.x was
developed at ACE95. The files necessary for this perl extension are now
(ACEDB 4.5 and later) included in the wrpc directory of the ACEDB directory
hierarchy. Documentation about how to extend perl is found at
http://probe.nalusda.gov:8000/ace97/perlace/perlacecl.html.

WWWAce and its successor webace were developed to provide a World Wide Web
interface for ACEDB. Webace instructions can be found at
http://probe.nal.usda.gov:8000/acedocs/webace.html, and
http://probe.nal.usda.gov:8000/ace97/webace.html and the program itself at
ftp://probe.nalusda.gov/pub/tools/webace.tar.gz.

A Java-based client called Jade allows communication via sockets to an
aceserver. Jade installation instructions and information on downloading can
be found at http://probe.nalusda.gov:8000/ace97/Jade.installation.html.

There are now development efforts underway to provide additional
client/server functionality to ACEDB including a CORBA server and
socket-based communications. These will likely be included in future
versions of ACEDB. A new C library interface to ACEDB internals will greatly
ease the development of new clients and servers that will support additional
protocols.
----------------------------------------------------------------------------

Q5: What documentation exists for ACEDB?

A5:

From Sam Cartinhour:
     The ACEDB Documentation Library is a repository for documentation
concerned with "A C. elegans Data Base", the generic genome database
software designed by Richard Durbin (MRC, UK) and Jean Thierry-Mieg (CNRS,
France). The server is intended as a resource for developers, curators, and
end-users of all (not just plant) databases derived from ace. The ACEDB
documentation server is sponsored by the Plant Genome Database Project at
the National Agricultural Library (USDA).

The WWW documentation server is part of the Agricultural Genome Information
System, at http://probe.nalusda.gov:8000/acedocs/. Documents in Postscript,
wordprocessor, and other non-html formats are available by ftp at
ftp://probe.nalusda.gov/pub/acedocs/. Information in the ACEDB Documentation
Library includes:

   * Primary documents from the developers Durbin & Thierry-Mieg, ca. 1992.
        o acedb -- A C. elegans Database: I. Users' Guide
        o acedb -- A C. elegans Database: II. Installation Guide
        o acedb -- A C. elegans Database: III. Configuration Guide
        o acedb -- A C. elegans Database: Syntactic Definitions for the
          ACEDB Data Base Manager
   * Tutorials, general and specific
   * Documentation written at the ACEDB Workshops
   * A repository of curator tools
   * A selection of models.wrm files from various databases
   * SampleDB, a sample database to demonstrate some ACEDB features, 1995
   * This FAQ, in html format

Other sources of documentation:

   * The ACEDB online help, a hypertext reader for the contents of the whelp
     directory of the ACEDB software distribution.
   * Contents of the wdoc, wtools, and wscripts directories.
   * Archives of the bionet.software.acedb newsgroup (both searchable)
        o http://www.bio.net/hypermail/ACEDB/, from BIOSCI
        o http://genome-www.stanford.edu/cgi-bin/biosci_acedb, from the
          Saccharomyces Genome Database site
   * ACEDB User's Guide in Japanese, from Tohru Sano, NEC,
     sano@exp.cl.nec.co.jp,
     http://www.cbi.or.jp/~sano/. (Postscript at http://www.labs.nec.co.jp/
     . Follow the prompts to register and "download the software".)
   * Paper publications
        o Cherry, J.M., Cartinhour, S.W., and Goodman, H.M. (1992). AAtDB,
          an Arabidopsis thaliana database. Plant Molecular Biology Reporter
          10: 308-309, 409-410.
        o Cherry, J.M. and Cartinhour, S.W. (1994). ACEDB, A tool for
          biological information. Pp. 347-356 in: Automated DNA Sequencing
          and Analysis, M. Adams, C. Fields, and C. Venter (Eds.). Academic
          Press. Online version:
          http://probe.nalusda.gov:8000/acedocs/overview.html.
        o Dunham, I., Durbin, R., Mieg, J-T & Bentley, D.R. (1994). Physical
          mapping projects and ACEDB. Pp. 111-158 in: Guide to Human Genome
          Computing. Bishop, M.J (Ed.). Academic Press.

Return to List of Questions
----------------------------------------------------------------------------

Q6: What newsgroups and mailing lists are available for ACEDB?

A6:

The USENET/BIOSCI conference bionet.software.acedb is dedicated to
discussions of ACEDB. The newsgroup can be accessed via a newsreader like rn
or tin, a WWW browser (news:bionet.software.acedb), or e-mail. To subscribe
to the e-mail version, send the message "subscribe acedb" to
biosci-server@net.bio.net. Mail sent to acedb@net.bio.net will be
distributed to all subscribers and to the electronic conference.

Articles posted to biosci.software.acedb are archived by BIOSCI at
http://www.bio.net/archives.html and by Mike Cherry at
http://genome-www.stanford.edu/cgi-bin/biosci_acedb.

There is also a separate mailing list for announcements of new releases of
the ACEDB (worm) database as well as the ACEDB software. To get on or off
this mailing list send mail to rd@sanger.ac.uk or mieg@kaa.crbm.cnrs-mop.fr.
The BIOSCI newsgroup is on this list.

Return to List of Questions
----------------------------------------------------------------------------

Q7 : Is there a repository of software tools for ACEDB curators?

A7:

Not really, but there are several partial ones. The main tools available are
for converting data from other formats to .ace format.

The Agricultural Genome Information System has a growing stock of useful
tools at http://probe.nalusda.gov:8000/acedocs/conversion.html. Some
additional ones were contributed at the ACE97 Workshop and can be found in
the Proceedings, http://probe.nalusda.gov:8000/ace97/tools/.

Mike Cherry maintains an archive of tools at
ftp://genome-ftp.stanford.edu/pub/acedb_dev/utilities/

For a general tool for converting data to ACEDB format input files, Joachim
Baumann (joachim.baumann@informatik.uni-stuttgart.de) has written the Perl
program TextConvert, available at ftp.informatic.uni.stuttgart.de/pub/DART/.

Return to List of Questions
----------------------------------------------------------------------------

Q8: When and where is the next ACEDB Workshop?

A8:

The next ACEDB meeting is planned for summer 1998 in England.

The ACE97 Conference and Workshop was held July 27 - August 9 at Cornell
University, Ithaca, New York, USA. See the ACE97 Proceedings Page,
http://probe.nalusda.gov:8000/ace97/proceedings.html for the results.

The Proceedings from the May 1995 ACEDB Conference are available at
http://probe.nalusda.gov:8000/acedocs/ace95/. A final summary report is
available at http://probe.nalusda.gov:8000/acedocs/ace95/ace95.final.html.
Also available online are collections of snapshots taken during the
conference by Frank Eeckman and by Dave Matthews.

For pictures of the ACEDB '94 Workshop in St. Matthieu de Treviers, see the
online collections:

   * by Mike Cherry at
     http://genome-www.stanford.edu/~cherry/pics/acedb-94.pics.html ;
   * by John Morris at http://weeds.mgh.harvard.edu/ace94/ace94.image.html ;
   * and by Brad Sherman at ftp://s27w007.pswfs.gov/ACEDB/ace94pix.html

Return to List of Questions
----------------------------------------------------------------------------

Q9: How does ACEDB compare to commercial relational DBMS's?

A9:

From Jean Thierry-Mieg, 4/97:

Obviously, i have a biased opinion, but i would say that acedb is to be
recommended if the following criteria are met:

1) A very complex schema, that cannot be developed at once, but will need
continuous refinement in parallel with the accumulation of the data

2) The type of questions that will be asked are rather complex, with rather
fuzzy answers, that one tries to refine progressively. The acedb browsing
capacities are useful in this case and have no equivalent in a relational
dbms

______________

I would rather recommend sybase in the following case

1) Simple schema, that can be designed from the start and does not contain
too many n.n relations and does not need recursivity

2) The type of questions that will be asked is: succession of de-correlated
simple questions with simple answers

____________________

Within this context, i would then list the following goodies of acedb:

1) The ace file format, which is a powerful system to prepare and exchange
data between data curators.

2) The existence of an easy graphic browsing interface

3) The availability of a biology-layer, if the application is about genetics

4) Portability (any unix machine), mac (with some limitations), windows (in
development) and price (ace is a freeware). This implies that you can
actually redistribute the complete system, say on a CD, something impossible
with sybase.

5) Ease of use, i seriously believe that ace is much easier to configure and
use than sybase.

_____________________

Finally one should consider the following question: concurrency.

Sybase has a well designed transaction system, which will allow roll backs
and refined lockings. This is essential for an application like a booking
agency, with many users in simultaneous write access.

Ace is much simpler minded. The graphic acedb creates a global lock allowing
a single user with write access at the time, and the modifications are not
echoed to the other "read access" users in real time.

The non graphic client server system allows parallel downloading of data by
many users, it is intended for example for collection of robots sending
their independent data in parallel. This is now well tested.

A graphic client system is being developed and now runs in our hands, but is
not yet released.

--

Therefore, if you do need real time simultaneous write access with partial
locks, and roll backs, use sybase/oracle

________________

Last issue is speed and quantities of data. In principle, sybase/oracle is
unlimited, whereas acedb needs to keep around 5-10% of the data in ram. But
this apparent difference is misleading.

On a 32 Meg machine, you can run ace with around 300.000 objects with a
complex schema at high speed. With say 1M objects, you will need more memory
or the performance would totally degrade because of swapping. However, this
is really a lot of data.

On a similar machine, your sybase oracle will work with that amount or more
data only if you do not perform too many joins. This implies that you are
asking simple questions from a simple schema which was indeed our first
criterion to choose sybase. If you start asking complex questions and make
joins, acedb is actually much more powerful.

During tests run on a big dec alpha server by Otto Ritter in decembre 1995
on several million biological objects with a complex schema, acedb was about
10 times faster than sybase, both to load the data and to answer queries.

I would therefore conclude that the quantity of data is not a criterion
pushing one way or the other, it is the complexity of the schema that
matters.

Return to List of Questions
----------------------------------------------------------------------------

Q10: How should ACEDB be cited?

A10:

From the distribution:
We realize that we have not yet published any "real" paper on ACEDB. We
consider however that anonymous ftp servers are a form of publication. We
would appreciate if users of ACEDB could quote:
Richard Durbin and Jean Thierry Mieg (1991-). A C. elegans Database.
Documentation, code and data available from anonymous FTP servers at
lirmm.lirmm.fr, cele.mrc-lmb.cam.ac.uk and ncbi.nlm.nih.gov.

Papers involved in database development could quote more precisely:
I. Users' Guide. Included as part of the ACEDB distribution kit,
II. Installation Guide. Included as part of the ACEDB distribution
III. Configuration Guide. Included as part of the ACEDB distribution
and the preprintkit available via anonymous ftp. Jean Thierry-Mieg and
Richard Durbin (1992). Syntactic Definitions for the ACEDB Data Base
Manager. Included as part of the ACEDB distribution.

--Jean and Richard.

Return to List of Questions
----------------------------------------------------------------------------

Q11: What ACEDB databases exist?

A11:

In alphabetic order by Database name

[Curators, please submit changes as new paragraphs. You may include html
links.]

A repository of many of these databases is maintained by the Agricultural
Genome Information System, both for anonymous ftp at
ftp://probe.nalusda.gov/pub and for WWW access via Webace at
http://probe.nalusda.gov:8000/alldbs.html.

Database : AaeDB
Species : Aedes aegypti (yellow fever mosquito)
ACEDB_version : 4.3
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : AalDB
Species : Aedes albopictus (Asian tiger (forest day) mosquito)
ACEDB_version : 4.3
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : ACeDB
Species : Caenorhabditis elegans
Current version: 4-8
Curator : Jean Thierry-Mieg, mieg@kaa.crbm.cnrs-mop.fr
Curator : Richard Durbin, rd@sanger.ac.uk
Curator : Sylvia Martinelli, sylvia@sanger.ac.uk
Availability: Unix and Macintosh versions via anonymous ftp
FTP: USA - ncbi.nlm.nih.gov in repository/acedb
FTP: England - ftp.sanger.ac.uk in pub/acedb
FTP: France - lirmm.lirmm.fr in genome/acedb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/other/
FAQ_updated : August 1995

Database : aCHEdb
Species : wide range of species
Subject : alpha/beta fold family of proteins database ESTHER. Sequences
phylogenetically related to cholinesterases (alpha/beta hydrolase,
carboxylesterases, lipases, adhesion molecules.)
Comment : Converted to ACEDB from the original ESTHER database.
ACEDB_version : UNIX 4.5, MacAce 4.0b4
Data_version : August 1997
Curator : Xavier Cousin - cousin@ensam.inra.fr
Curator : Thierry Hotelier - hotelier@ensam.inra.fr
Curator : Arnaud Chatonnet - chatonne@ensam.inra.fr
Contact : chedb@ensam.inra.fr
Availability: Unix and Macintosh versions via anonymous ftp
FTP: ftp://ftp.toulouse.inra.fr in pub/esther
WWW : http://www.ensam.inra.fr/cholinesterase
FAQ_updated : September 1997

Database : AgaDB
Species : Anopheles gambiae (malaria mosquito)
ACEDB_version : 4.3
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : AGsDB (A Genus species Database)
Species : Aspergillus nidulans
Species : Neurospora crassa
Species : Bos taurus (cow)
Species : Homo sapiens anchor loci
Species : Gossypium hirsutum (cotton)
Species : Neurospora crassa
Species : Homologs of Aspergillus cell cycle loci for budding and fission
yeast
Curator : Leland Ellis, leland@straylight.tamu.edu
ACeDB_version : 3.0
Subject: Contains extensions to the Human C21 Models to provide for multiple
species, and queries between species via Homologs (e.g., cell cycle loci
with links via Homologs between Aspergillus and budding C. cerevisiae) and
fission (S. pombe yeast); interacting loci via defined Interactions for each
locus Revision : AAnDB for Aspergillus nidulans and ABtDB for Bos taurus
(cow) have been folded into AGsDB, and are not being developed futher as
individual species databases.
WWW : http://keck.tamu.edu/cgi/agsdb/agsdbserver.html FTP:
ftp://keck.tamu.edu/pub/agsdb/agsdb1_0_acedb3_0_solaris2.3.tar.Z
FAQ_updated : March 1994

Database : Alfagenes
Species : Medicago sativa (alfalfa)
Curator : D. Z. Skinner, dzolek@ksu.ksu.edu
Telephone : (913) 532-7247
ACEDB_version : 3.0
FTP : probe.nalusda.gov in pub/alfagenes
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : July 1995

Database : AnoDB
Species : Anopheles sp.
ACEDB_version : 4.5
WWW : http://konops.imbb.forth.gr/AnoDB/
Curator : Christos Louis, louis@konops.imbb.forth.gr
Co-Curator : Pantelis Topalis, topalis@konops.imbb.forth.gr
Contact : AnoDB-comments@konops.imbb.forth.gr
Data_updated : regularly
FAQ_updated : August 1997

Database : AtDB
Species : Arabidopsis thaliana
ACEDB_version : UNIX 4.3, MacAce 4.0b4
Data_version : 4-7
PI : J. Michael Cherry
Curator : David Flanders
Contact : arab-curator@genome.stanford.edu
Availability : UNIX and Macintosh versions via anonymous ftp
FTP : genome-ftp.stanford.edu in arabidopsis/AtDB
FTP : ncbi.nlm.nih.gov in repository/AtDB
WWW : http://genome-www.stanford.edu
FAQ_updated : December 1996

Database : AtrDB
Species : Aedes triseriatus (Eastern tree hole mosquito)
ACEDB_version : 4.3
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : BeanGenes
Species : Phaseolus and Vigna
Curator : Phillip E. McClean, mcclean@beangenes.cws.ndsu.nodak.edu
ACEDB_version : 4.1
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : September 1995

Database : BrassicaDB
Species : Brassica napus (Canola/Oilseed Rape) and its parental diploid
species
ACEDB_version : 4.3
Description : Genetic maps of Brassica napus, QTL analyses for agronomic
traits, literature references and B. napus-specific DNA sequences will be
incorporated. We aim to integrate with B. napus genetic maps developed
elsewhere and to produce a Java interface that will link BrassicaDB with the
AAtDB (Arabidopsis thaliana) database through gene orthologies that are
becoming established between these closely related plant genomes.
PI : Martin Trick, Martin.Trick@bbsrc.ac.uk
Curator/Developer : Mazda Hewitt, Mazda.Hewitt@bbsrc.ac.uk
WWW : http://synteny.nott.ac.uk/brassica.html
Data_updated : Under development
FAQ_updated : August 1997

Database : ChlamyDB
Species : Chlamydomonas
Curator : Elizabeth Harris
Contact : chlamy@acpub.duke.edu
ACEDB_version : 3.0
Data_version : 1.2
Availability : Macintosh and UNIX versions via anonymous ftp
FTP : probe.nalusda.gov in pub/chlamydb
Gopher : ftp.duke.edu/11/pub/chlamy
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : August 1995

Database : CIMMYT (Wheat International Nursery Data)
Species : Triticum spp.
ACEDB_version : 4.0
Curator : Hector Sanchez, hsanchez@cimmyt.mx
FTP : probe.nalusda.gov in pub/cimmyt
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : September 1995

Database : CoolGenes
Species : Cool Season Food Legumes; Pisum, Lens, Cicer, Lathyrus, Vicia faba
Curator : Fred Muehlbauer, muehlbau@wsu.edu
ACEDB_version : 3.0
Gopher : gopher://probe.nalusda.gov:7000/11/genome.databases/coolgenes/
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : January 1996

Database : CottonDB
Species : Gossypium hirsutum (cotton) and related species
PI : Russell J. Kohel (rjk0339@acs.tamu.edu), USDA-ARS, Southern Crops
Research Laboratory, 2765 F&B Road, College Station, Texas 77845
Curator : Gerard R. Lazo, lazo@tamu.edu
Curator : Sridhar Madhavan, msridhar@tamu.edu
Phone : 409-260-9311
Fax : 409-260-9333
ACEDB_version : 3.0
Data_version : January 1995 (version 95.1)
FTP : probe.nalusda.gov in pub/cottondb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
Data_submission_form : http://algodon.tamu.edu/
FAQ_updated : January 1995

Database: Cruzdb
Species: Trypanosoma cruzi
PI: Wim Degrave
ACEDB_version: 4.3
Curator: Martin Aslett
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: (when available) ftp.ebi.ac.uk/pub/databases/parasites/cruzi/
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
Data_updated : In development
FAQ_updated : November 1996

Database : CSNDB
Focus : Cell Signaling Networks
Species : human
Curator : Takako Igarashi, taka@nihs.go.jp
Curator : Tsuguchika Kaminuma, kaminuma@nihs.go.jp
Assistant_Curator : Masumi Yukawa, yukawa@nihs.go.jp
Assistant_Curator : Shikiko Hasegawa, shasegaw@nihs.go.jp
Contact : Takako Igarashi, taka@nihs.go.jp
ACeDB_version : 4.1
Data : molecular data of signal molecules, molecular data of signal
transductions, signal transduction pathways, domain structure and function
of signal molecules, and three dimensional structures of signal molecules.
Availability : CSNDB is on WWW. WWW-browser is required to attach molecular
viewer RasMol (ftp: colonsay.dcs.ed.ac.uk ) for displaying three dimensional
structure of protein.
WWW : http://geo.nihs.go.jp/csndb.html

Database : CupDB
Species : Culex pipiens
ACEDB_version : 4.3
WWW : currently unavailable via www
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : Cyanoace
Species : Cyanobacterium synechocystis sp. strain PCC6803
Developer : Nobuyuki Miyajima, miyajima@kazusa.or.jp
Comment : Converted to ACEDB from Sybase
FTP : ftp://ftp.kazusa.or.jp/pub/acedb/cyanoace/
WWW : http://www.kazusa.or.jp/cyanobase/
Remark : WWW interface uses Java enhanced clickable maps.
FAQ_updated : December 1996

Database : EthnobotDB (worldwide plant uses)
Species : wide range of plant species
ACEDB_version : 4.0
Comment : Converted to ACEDB from the original SQL database.
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov
Curator : James A. Duke, ngrljd@ars-grin.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : June 1995

Database: FilDB
Species: Filarial nematodes
PI: Mark Blaxter
ACEDB_version: 4.3
Curator: Martin Aslett
Contact: Mark Blaxter, mark.blaxter@ed.ac.uk
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: (when available) ftp.ebi.ac.uk/pub/databases/parasites/Brugia
WWW: http://helios.bto.ed.ac.uk/mbx/fgn/filgen.html
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
Data_updated: In development
FAQ_updated : November 1996

Database : FoodplantDB (Native American Food Plants)
Species : Over 1,100 plant species
ACEDB_version : 4.0
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov
Curator : James A. Duke, ngrljd@ars-grin.gov
Comment : Converted to ACEDB from ORACLE.
Comment : Data originally from a publication by Yanovsky, Elias. 1936. Food
Plants of the North American Indians. USDA Miscellaneous Publication Number
237.
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : May 1995

Database : GrainGenes
Species : Wheat, barley, oats, sugarcane, relatives
Curator : David E. Matthews, matthews@greengenes.cit.cornell.edu
Curator : Gerard R. Lazo, lazo@pw.usda.gov
PI : Olin D. Anderson, oandersn@pw.usda.gov
ACEDB_version : 4_3 (Unix), 4.1b1 (MacAce)
Data_version : 1.7, December 1996
Availability : UNIX and Macintosh versions via anonymous ftp
Availability : Macintosh version on CD-ROM "RiceMac / MacGrainGenes", from
Dr. Baek Hie Nahm, Korea Rice Genome Research Program, Myongji University,
Yongin, Korea.
FTP : probe.nalusda.gov in pub/graingenes
FTP : grain.jouy.inra.fr in pub/database
Gopher : greengenes.cit.cornell.edu
Gopher : grain.jouy.inra.fr
Gopher : probe.nalusda.gov:7002
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://wheat.pw.usda.gov/
WWW : http://grain.jouy.inra.fr
Data_updated : December 1996
FAQ_updated : December 1996

Database : IGD (Integrated Genomic Database)
Species : Homo sapiens
Subject : Chromosome 21
Availability : September 1994 by ftp, on-line server October 1994
Contact : Otto Ritter, o.ritter@dkfz-heidelberg.de
Contact : Jean Thierry-Mieg, mieg@kaa.cnrs-mop.fr
Contact : Nicole Creau-Goldberg, creau@arthur.citi2.fr
Contact : Jean-Maurice Delabar, delabar@arthur.citi2.fr
Description : IGD (Integrated Genomic Database) aims to integrate multiple
public general molecular biology and human genome specific databases into
single logical database with unified interface to existing analysis tools.
From data produced by the 4th International Workshop on Chromosome 21
(Genomics,1993,18,735-744) and from data provided by or taken from the
following databases and data repositories: GDB, OMIM, EMBL, CEPH, Genethon,
UKProbeBank, and RLDB.

Database : IXDB (Integrated X chromosome DataBase)
Species: Homo sapiens
Subject: Chromosome X
Acedb_version : 4.1
Data: The YAC map constructed by the Max-Planck-Institut fuer Molekulare
Genetik in Berlin, with all the attached experimental data necessary to
reconstruct the map. Information on each of 9000 YAC clones mapped to the X
chromosome, and constituting the YAC collection assembled with clone sets
from 14 different laboratories worldwide.
Latest_release:March 1996
Curator: Hugues Roest Crollius, roest@mpimg-berlin-dahlem.mpg.de
Contact: Ulf Leser, leser@mpimg-berlin-dahlem.mpg.de
PI: Hans Lehrach
FTP: ftp.mpimg-berlin-dahlem.mpg.de in directory pub/lehrach/x-map
WWW: http://www.mpimg-berlin-dahlem.mpg.de/~xteam

Database: Leishdb
Species: Leishmania major, L. infantum, L. peruviana, L. donovani and others
PI: Jennie Blackwell
PI: Al Ivens
ACEDB_version: 4.3
Curator: Martin Aslett
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: ftp.ebi.ac.uk/pub/databases/parasites/Leish
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
WWW: http://www.ebi.ac.uk/parasites/leish/leishpage.html (in development)
Data_updated: October 1996
FAQ_updated : November 1996

Database : LIGM-DB
Curator : Veronique Giudicelli
Focus : genetic and physical mapping of loci of Immunoglobulins and Tcell
receptors
PI : Marie-Paule Lefranc
Contact : Veronique Giudicelli, LIGM IGMM UMR CNRS 9942, BP 5051 Rte de
Mende, 34000 Montpellier, giudi@ligm.crbm.cnrs-mop.fr

Database : MaizeDB
Species : Zea mays L. ssp. mays and related species
Content : Maps, raw map data, loci, probes, genetic stocks, variations,
mutant images, agronomic traits, gene products, QTL, bibliography, colleague
addresses; hardlinks to sequence and germplasm databases.
Latest_release : Oct 1996
Acedb_version : 4.1
Curator : Mary Polacco, maryp@teosinte.agron.missouri
PI : Ed Coe, Jr., ed@teosinte.agron.missouri.edu
Systems : Denis Hancock, dhancock@teosinte.agron.missouri.edu
FTP : probe.nalusda.gov/pub/maizedb/macedist961001.tar.gz
WWW : http://www.agron.missouri.edu
WEBACE : http://probe.nalusda.gov:8300/
Contact : db_request@teosinte.agron.missouri.edu
Comment : Data are periodically extracted into ACEDB format from Sybase
Comment : Genera software used to maintain the Sybase database and its
gateways, except for ACEDB
Comment : ACEDB releases are announced on the MAIZE bulletin board;
http://www.bio.net/hypermail/MAIZE/
Comment : WEBACE records are hardlinked to the Sybase server where data are
curated
Funding : USDA ARS Plant Genome Research Program
FAQ_updated : Mar 7, 1997

Database : Mendel (plant wide gene names)
Species : wide range of plant species
Subject : standardized designations for sequenced genes
Comment : The purpose is to provide a common system of nomenclature for
substantially similar genes across the plant kingdom. Mendel is maintained
by the Commission on Plant Gene Nomenclature.
ACEDB_version : 4.0
Curator : Carl Price, price@mbcl.rutgers.edu
Curator : Ellen Reardon, reardon@mbcl.rutgers.edu
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : July 1995

Database : Millet Genes
Species : Pennisetum glaucum (Pearl Millet)
ACEDB_version : 4.3
Curator : Matt Couchman, Matthew.Couchman@bbsrc.ac.uk
PI : Katrien Devos, Katrien.Devos@bbsrc.ac.uk
FTP: ftp://jiio5.jic.bbsrc.ac.uk/pub/millet
WWW : http://synteny.nott.ac.uk/millet.html
WWW : http://jiio5.jic.bbsrc.ac.uk:8000/index.shtml
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : March 1997

DataBase : Mousedb
Species : Mus Musculus
Species : Homo Sapiens
ACEDB_version : 3.0 with extensions to define and display cytogenetic data.
Description : Mouse genome data from the published literature, including
mouse genes with phenotypic effects, chromosome anomalies, imprinted regions
and man-mouse homologies with associated pathological disorders. The maps
are consensus ones. They use data, such as the HIS and anomaly data, to show
alignments between the genetic and cytogenetic maps.
Curator : Rachael Selley, rselley@har-rbu.mrc.ac.uk
PI : Mary Lyon
PI : Jo Peters
Availability : Mousedb is available publicly from the UK HGMP Resource
Centre's computing service via the INTERNET. For user id. please contact
Administration, HGMP Resource Centre, Hinxton Hall, Cambridgeshire CB10 1RQ,
UK.
Tel: (+44) 1223 494520 Fax: (+44) 1223 494510
Contact : Rachael Selley, MRC Radiobiology Unit, Chilton, Didcot, Oxon OX11
ORD
FAQ_updated : July 1995

Database : MPNADB (Medicinal Plants of Native America)
Species : Over 2,100 plant species
Curator : Daniel E. Moerman, dmoerman@umich.edu
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov - ACEDB version

Comment : MPNADB is based on a two-volume book of the same name published in
1986 by the Museum of Anthropology of the University of Michigan. MPNADB was
first developed at the University of Michigan in DBase II.
ACEDB_version : 4.0
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : June 1995

Database : MsqDB
Species : Interspecies Mosquito database
ACEDB_version : 4.3
WWW : http://klab.agsci.colostate.edu/
Curator : Dennis Knudson, dknudson@lamar.colostate.edu
Co-Curator : Dave Severson, dave@aedes.vetsci.wisc.edu
Co-Curator : Leonard Munstermann, munst@biomed.med.yale.edu
Contact : aaedbmgr@klab.agsci.colostate.edu
Data_updated : regularly
FAQ_updated : April 1997

Database : MycDB
Species : Mycobacteria
Comment : MycDB is a collation of data on the mycobacteria, causative agents
of tuberculosis and leprosy. It is centered on the mapping and sequencing
projects under way in M.leprae and M.tuberculosis.
Curator : Staffan Bergh, staffan@biochem.kth.se
Curator : Stewart Cole, stcole@pasteur.fr
ACEDB_version : 4.3
Data_version : 4-22 (December 1996)
FTP : www.biochem.kth.se (130.237.52.64) in pub/MycDB
FTP : ftp.pasteur.fr (157.99.64.12) in pub/MycDB
FTP : bioinformatics.weizmann.ac.il (132.76.55.12) in
pub/databases/acedb/mycdb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://www.biochem.kth.se/MycDB.html
WWW : http://probe.nalusda.gov:8300/other/
FAQ_updated : December 1996

Database : OMIA (Online Mendelian Inheritance in Animals)
Species : wide range of animal species
Subject : gene and phene (familial trait or phenotype) information
Comment : MIA is modeled after Victor McKusick's Mendelian Inheritance in
Man (MIM) database and was developed at the University of Sydney, Australia,
in Advanced Revelation.
Curator : Frank Nicholas, frankn@doolittle.vetsci.su.oz.au
ACEDB_version : 4.0
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/animal/
WWW : http://morgan.angis.su.oz.au/BIRX/phenes_form.html
FAQ_updated : September 1995

Database : PhytochemDB (Plant Chemicals)
Species : wide range of plant species
Subject : Consists primarily of plant chemical data, including quantity,
taxonomic occurrence, and chemical activity.
Comment : Converted to ACEDB from the original SQL database.
ACEDB_version : 4.0
Data_version : July 1994
Curator : Stephen M. Beckstrom-Sternberg, peosb@ars-grin.gov
Curator : James A. Duke, ngrljd@ars-grin.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : June 1995

Database : PomBase
Curator : Sean Walsh, svw@sanger.ac.uk
Curator : Marie-Adele Rajendream
PI : Bart Barrell, barrell@sanger.ac.uk
Species : Schizosaccharomyces pombe
ACEDB_version : 4.1
FTP : ftp.sanger.ac.uk in pub/PomBase
FAQ_updated : September 1995

Database : PVP (Plant Variety Protection)
Species : Glycine max (soybeans)
Subject : Data about plant varieties that have been granted a Certificate of
Protection by the Plant Variety Protection Office.
Curator : Stephen M. Beckstrom-Sternberg, sbeckstr@nalusda.gov - ACEDB
version
ACEDB_version : 4.0
Contact: The Plant Variety Protection Office, Room. 500, National
Agriculture Library, 10301 Baltimore Blvd., Beltsville, Maryland 20705
Telephone : 301-504-5518
Fax : 301-504-5291
Email : Jeff Strachan, strachan@locus.nalusda.gov
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/related/
FAQ_updated : June 1995

Database : RiceGenes
Species : Oryza sativa
Curator : Edie Paul, epaul@nightshade.cit.cornell.edu
PI : Susan McCouch
ACEDB_version : 4.1
FTP : probe.nalusda.gov in pub/ricegenes
Gopher : nightshade.cit.cornell.edu
Gopher : probe.nalusda.gov:7007
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : November 1996

Database : SacchDB
Species : Saccharomyces cerevisiae
Subject : Budding (common baker's) Yeast Genome
ACEDB_version : UNIX 4.3, MacAce 4.0b4
Data_version : 4.6
Data : All Saccharomyces genes contained in the Registry of Gene Names.
Results of the completed chromosomal sequencing projects have been
integrated into the database. Physical Maps based on DNA sequencing
projects, hybridization to the Olson/Riles prime filter grids, and
restriction mapping. For the completely sequenced chromosomes the Olson
prime clones have been re-mapped (on the computer) to the DNA sequence.
Saccharomyces DNA sequences contained within GenBank are incorporated.
Literature references, most including abstracts, for the information
contained within the database. Gene protein product information obtained
from the YPD database (Garrels and Latter, CSHL) and the literature. Genetic
Maps including the underlying two point tetrad data. Including all tetrad
data reported in previous additions of the Mortimer Yeast Maps.
FTP : genome-ftp.stanford.edu in pub/yeast/SacchDB
FTP : ncbi.nlm.nih.gov in repository/SacchDB
WWW : http://genome-www.stanford.edu/
Funding : National Center for Human Genome Research, NIH
PI : David Botstein, botstein@genome.stanford.edu
Project Manager/Curator : Mike Cherry, cherry@genome.stanford.edu
Curator : Selena Dwight, dwight@genome.stanford.edu
Curator : Cathy Ball, ball@genome.stanford.edu
Curator : Caroline Adler, adler@genome.stanford.edu
Curator : Yankai Jia, jia@genome.stanford.edu
Programmer : Gail Juvik, gjuvik@genome.stanford.edu
Programmer : Shuai Weng, shuai@genome.stanford.edu
Sys. Admin : Mark Schroeder, mark@genome.stanford.edu
Contact : yeast-curator@genome.stanford.edu
Data_Submission : yeast-curator@genome.stanford.edu
FAQ_updated : September 1996

Database: SchistoDB
Species: Schistosoma mansoni (plus other schistosomes)
PI: David Johnston
ACEDB_version: 4.3
Curator: Martin Aslett
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: (when available) ftp.ebi.ac.uk/pub/databases/parasites/Schisto/
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
Data_updated: In development
FAQ_updated : November 1996

Database : SolGenes
Subject : Solanaceae - tomato, potato, pepper
Curator : Sam Beer, sbeer@nightshade.cit.cornell.edu
PI : none currently
Release : ACEDB 4.3
FTP : probe.nalusda.gov in pub/solgenes
Gopher : nightshade.cit.cornell.edu:71
Gopher : probe.nalusda.gov:7006
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
Data_updated : May 1997
FAQ_updated : May 1997

Database : SorghumDB
Species : Sorghum bicolor (L.) Moench
PI : Keith F. Schertz, schertz@tamvm1.tamu.edu
USDA-ARS, Dept. of Soil & Crop Sciences, Texas A&M University, College
Station, TX 77843-2474
Phone : (409) 260-9252
FAX : (409) 845-0456
Curator : Najeeb U. Siddiqui, nus6389@tam2000.tamu.edu
Southern Crop Improvement Facility, Crop Biotechnology Center, Texas A&M
University, College Station, TX 77843-2123
Phone : (409) 862-1523
FAX : (409) 862-4790
ACEDB_version : 3.0
Data_version : 2.0
FTP : probe.nalusda.gov in pub/sorghumdb
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
FAQ_updated : September 1995

Database : SoyBase
Species : Glycine max (Soybeans) and related species
PI : Randy Shoemaker, rcsshoe@iastate.edu
Curator : David Grant, dgrant@iastate.edu
Assistant_curator : Marica Imsamde, mimsande@iastate.edu
Contact : David Grant, dgrant@iastate.edu
ACEDB-Version : 3.7
FTP : probe.nalusda.gov in pub/soybase
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://macgrant.agron.iastate.edu
FAQ_updated : October 1995

Database : Syndb
Species : Homo sapiens, Mus musculus
Subject : STS content mapping & directed sequencing of Human Chromosomes
21,5 with Mouse for syntenic comparison
ACEDB_version : acedb v3.3 plus moulon server
FTP : genome.lbl.gov in pub/acedb/
WWW : http://genome.lbl.gov/Genome/acepage.html
Curator : Donn F. Davy, DFDavy@lbl.gov
Contact : Arun K. Aggarwal, aggarwal@genome.lbl.gov
PI : Michael Palazzolo
PI : Chris Martin
PI : Jan-Fang Cheng, jcheng@genome.lbl.gov
FAQ_updated : October 1994

Database: ToxoDB
Species: Toxoplasma gondii
PI: David Sibley
PI: David Roos
PI: Jim Ajioka
ACEDB_version: 4.3
Curator: Martin Aslett
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: ftp.ebi.ac.uk/pub/databases/parasites/Toxo/
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
WWW: http://www.ebi.ac.uk/parasites/toxo/toxpage.html
Data_updated: October 1996
FAQ_updated: November 1996

Database : TreeGenes
Species : Forest trees
ACEDB_version : 4.3
Curator : Bradley K. Sherman, bks@s27w007.pswfs.gov
PI : David B. Neale, dbn@s27w007.pswfs.gov
Contact : Dendrome@s27w007.pswfs.gov
FTP : probe.nalusda.gov in /pub/treegenes
Gopher : s27w007.pswfs.gov/
Gopher : probe.nalusda.gov:7508/
Gopher : probe.nalusda.gov:7000/11/genome.databases/
WWW : http://probe.nalusda.gov:8300/plant/
WWW : http://s27w007.pswfs.gov/
FAQ_updated : May 1996

Database: Trypbase
Species: Trypanosoma brucei
PI: Sara Melville
ACEDB_version: 4.3
Curator: Howard Cobb
Curator: Martin Aslett
Contact: Sara Melville, sm160@mole.bio.cam.ac.uk
Contact: Martin Aslett, aslett@ebi.ac.uk
FTP: ftp.ebi.ac.uk/pub/databases/parasites/brucei
WWW: http://parsun1.path.cam.ac.uk/newtryp/toppage.htm
WWW: http://www.ebi.ac.uk/parasites/parasite-genome.html
Data_updated: October 1996
FAQ_updated: November 1996

Database : 21Bdb
Species : Homo sapiens
Subject : STS content mapping and sequencing of Human Chromosome 21
ACEDB_version : acedb.1-10 plus moulon server
Curator : Donn F. Davy, DFDavy@lbl.gov
Contact : Arun K. Aggarwal, aggarwal@genome.lbl.gov
PI : Michael Palazzolo
PI : Chris Martin
PI : Jan-Fang Cheng, jcheng@genome.lbl.gov
FTP : ftp://genome.lbl.gov in pub/acedb/
WWW : http://genome.lbl.gov/Genome/acepage.html
FAQ_updated : April 1994

Database : 11Db
Species : Homo sapiens
Subject : Physical and Genetic mapping of Human Chromosome 11 Description :
11Db attempts to show as full a picture as possible of the genetic and
physical maps of Human Chromosome 11. It has two new displays, one which
attempts to integrate as much of the mapping data as possible using minimal
intervals, and one which displays YAC Contigs downloaded from SEGMAP
datafiles.
Contact : Benedict Arnold (b.arnold@bc.ic.ac.uk)
PI : Peter Little (p.little@bc.ic.ac.uk)
ACEDB_version : based on 4_1 with added map displays.
ACEDB_version : based on 3_6 with added map displays.
Data version : 1.0
Last Update : December 1995
WWW : http://chr11.bc.ic.ac.uk
FTP : ftp.cc.ic.ac.uk
Description : 11Db attempts to show as full a picture as possible of the
genetic and physical maps of Human Chromosome 11. It has two new displays,
one which attempts to integrate as much of the mapping data as possible
using minimal intervals, and one which displays YAC Contigs downloaded from
SEGMAP datafiles.

Database : 22ace
Species : Homo sapiens
Subject : Physical map of human chromosome 22, genomic sequencing and more
ACEDB_version : 4.1
Curator : Ian Dunham, id1@sanger.ac.uk
Curator : Gareth Maslen, glm@sanger.ac.uk
PI : Ian Dunham
FTP : ftp.sanger.ac.uk in pub/human/chr22/physical_map/
WWW : http://www.sanger.ac.uk/hum22/
FAQ_updated : August 1995

Database : VoxPop
Species : Populus species
Curator : Carl G. Riches, cgr@poplar1.cfr.washington.edu
PI : Reinhard F. Stettler, STETTLER@coyote.cfr.washington.edu
ACEDB_version : 1.9
FTP : poplar1.cfr.washington.edu in /pub/
Gopher : poplar1.crf.washington.edu

Return to List of Questions
----------------------------------------------------------------------------

Q12:Who prepared this document & where is the current version?

A12:

This document is posted monthly to the BIOSCI newsgroup
bionet.software.acedb and to USENET conference news.answers. It is intended
to be used as an index to ACEDB databases and to information about the
database software.

The WWW version of this document is at:
http://probe.nalusda.gov:8000/acedocs/acedbfaq.html

A text version is available via anonymous ftp at machine rtfm.mit.edu as
pub/usenet/news.answers/acedb-faq. If you only have electronic mail, the FAQ
can be retrieved from mail-server@rtfm.mit.edu.

Curators of ACEDB databases should take note of Question 4 and keep me
apprised of changes.

Errors of commission or omission are unintentional. If I have forgotten to
give you credit please let me know. Please send comments and corrections to:
acedbfaq@s27w007.pswfs.gov

This FAQ was created and maintained from 1993 - 1996 by Bradley K. Sherman.
Major contributions in getting it off the ground were made by Mike Cherry,
John McCarthy, and Doug Bigwood. Other contributors include:

   * Lisa Lorenzen
   * David Matthews
   * Edie Paul
   * Donn Davy
   * Eric De Mund
   * Sam Cartinhour

It is currently maintained by Dave Matthews.

Please cite as:
Matthews, D.E., and B.K. Sherman, ACEDB Genome Database Software FAQ,
ftp://rtfm.mit.edu/pub/usenet/news.answers/acedb-faq,
http://probe.nalusda.gov:8000/acedocs/acedbfaq.html, 1993-1997, approx. 70K
bytes.

To add or modify information in this document, please send mail to:
acedbfaq@s27w007.pswfs.gov

The GrainGenes Project is funded by the USDA ARS Plant Genome Research
Program.

Return to List of Questions
----------------------------------------------------------------------------

From owner-acedb@net.bio.net Tue Sep 30 23:00:00 1997
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.software.acedb
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 1 Oct 1997 02:00:08 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 233
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199710010900.CAA19651@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.


From owner-acedb@net.bio.net Tue Sep 30 23:00:00 1997
From: aslfjasd4095r3409@lafjsadj.com
Subject: HP Toner Cartridge Blowout
Newsgroups: bionet.software.acedb
NNTP-Posting-Host: ppp11030.la.inreach.net
Message-ID: <3431c1a3.0@news.inreach.com>
Date: 1 Oct 97 03:21:07 GMT
Lines: 64
Path: biosci!rutgers!nntp.upenn.edu!news.misty.com!www.nntp.primenet.com!globalcenter0!news.primenet.com!nntp.primenet.com!news.idt.net!news-peer-east.sprintlink.net!news-peer.sprintlink.net!news-sea-19.sprintlink.net!news-in-west.sprintlink.net!news.sprintlink.net!Sprint!208.25.48.5!news.inreach.com!ppp11030.la.inreach.net


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