From owner-ageing@net.bio.net Sun Jul 04 23:00:00 1993 Path: biosci!daresbury!daresbury!news From: bafa1@central.sussex.ac.uk (Sydney Shall) Newsgroups: bionet.molbio.ageing Subject: Ageing and Function Message-ID: <1993Jul5.101242.22738@gserv1.dl.ac.uk> Date: 5 Jul 93 10:11:23 GMT Sender: list-admin@daresbury.ac.uk Distribution: bionet Lines: 65 Original-To: ageing@uk.ac.daresbury X-Mailer: ELM [version 2.3 PL11] Recently, in a discussion of the evolution of ageing by T. Donaldson, I found a small lack of clarity in the use of the term "ageing". Donaldson correctly points out that we are all agreed that the immediate priority is to ensure improved physiological and mental function among older people. This must certainly take precedence over elongation of the lifespan of people. This is absolutely true, and is probably universally aggreed. The problem arises inasmuch as this formulation begs an underlying question; namely, how is the lifespan to be elongated and how are we to improve the functioning and well-being of older people. At first sight, it may appear that the two objectives are unrelated, but closer inspection shows that the two aims are perhaps closely linked. For example, if we were to improve neonatal survivial, which in most communities would be technically feasible and technically easy, we would substantially increase the expected lifespan in those communities. By contrast, in rich communities it may be the case that the source of some serious disabilites and mortality, may be ultimately due to an inadequate ability to reproduce important stem cells in crucial tissues such as the blood vessels. Improvement of the reproductive ability of arteriolar stem cells may lead to decreased arterial pathology, and this in turn may lead to decreased morbidity and mortality, in addition; the increased cell proliferation may in itself increase the lifespan of the carrier. Thus, since we have not yet been able to clearly dissect out human pathology from "age" related decline in function, it remains very unclear what the precise relation between pathology and "ageing" in whole organisms actually is. I would strongly recommend that we should should use terms like "age" and "ageing" very sparingly. Lifespan is a term that can in principle be easily quantified. Similarly, one can define physiological and behavioural levels reasonable well. Therefore, these measures are more useful to us. ************************************************************************** ************************************************************************** Sydney SHALL, Laboratory of Cell and Molecular Biology, Biology Building, University of Sussex, Brighton, East Sussex BN1 9QG, ENGLAND. Telephone: +44.273.67.83.03 FAX: +44.273.67.83.33 E-Mail: Janet: BAFA1@uk.ac.sussex.central Elsewhere: BAFA1@central.sussex.ac.uk EARN/BITNET: BAFA1%sussex.central@ukacrl ******************************************************************************* ******************************************************************************* From owner-ageing@net.bio.net Mon Jul 05 23:00:00 1993 Path: biosci!uwm.edu!wupost!spool.mu.edu!agate!headwall.Stanford.EDU!nntp.Stanford.EDU!tkw From: tkw@leland.Stanford.EDU (Todd Whitehurst) Newsgroups: bionet.molbio.ageing Subject: Talk on Ageing by Prominent Researcher Message-ID: <1993Jul6.042844.22205@leland.Stanford.EDU> Date: 6 Jul 93 04:28:44 GMT Sender: news@leland.Stanford.EDU (Mr News) Distribution: ba Organization: Stanford University, California Lines: 52 I saw this posted in su.events & I thought it would be of interest of others in this group who are also in the Bay area. ******************************************************************** PARC Forum Thursday July 8, 1993 Xerox PARC Auditorium, 4:00 PM BIOLOGY OF HUMAN AGING Leonard Hayflick University of California, San Francisco Our finding that normal human and animal cells age in laboratory cultures just as they do in the animals or humans from which they were obtained overturned the dogma held since the turn of the century that cultured cells are immortal. We proposed that aging results from intracellular events, a proposal now widely confirmed. Two of the observations that support this are: 1) The number of population doublings of cultured normal human fibroblasts is inversely proportional to donor age. 2) A direct proportionality may exist between population doubling potential and the maximum lifespan of many animal species. It seems that a molecular clock is present in cells. One recent discovery that merits attention is the loss of the telomeric sequences TTAGGG as normal cells age in vitro and in vivo. Could this be the molecular clock? ----------------------- This Forum is OPEN to the public. All are invited. For more information contact Ralph Merkle at (415) 812-4422 (merkle@xerox.com) Refreshments will be served at 3:45 P.M. for Forum Attendees only. Requests for videotapes *Xerox Employees Only* should be sent to Susie Mulhern (Mulhern:PARC:Xerox). The PARC Auditorium is located at 3333 Coyote Hill Rd. in Palo Alto. We are in the Stanford Research Park, between Page Mill Road (west of Foothill Expressway) and Hillview Avenue. The easiest way here is to get onto Page Mill Road, then turn onto Coyote Hill Road. As you drive up Coyote Hill past the horse pastures, PARC is the building on the left after you crest the hill. Park in the large lot, and enter the auditorium at the upper level of the building. (The auditorium entrance is located down the stairs and to the left of the main doors.) Upcoming Speakers: Thursday, July 15, 4pm, Paul Saffo, Institute for the Future, Never Mistake A Clear View for a Short Distance (and other lessons from innovation in the information revolution). From owner-ageing@net.bio.net Mon Jul 05 23:00:00 1993 Path: biosci!agate!howland.reston.ans.net!darwin.sura.net!wvnvms.wvnet.edu!marshall.wvnet.edu!newsmgr From: JSMIT@UKANVM.BITNET (Johanna Smit, Pharm.D.) Newsgroups: bionet.molbio.ageing,bit.listserv.gerinet Subject: Message-ID: Date: 6 Jul 93 18:30:27 GMT Sender: Geriatric Health Care Discussion Group Reply-To: Geriatric Health Care Discussion Group Lines: 1 Xref: biosci bionet.molbio.ageing:454 To: IN%"NEWSMGR@muvms6.wvnet.edu" "Marshall University" CC: Subj: Return-path: <@UBVM.CC.BUFFALO.EDU:owner-gerinet@UBVM.CC.BUFFALO.EDU> Return-path: JSMIT <@UBVM.CC.BUFFALO.EDU:JSMIT@UKANVM.BITNET> To: Marshall University Content-transfer-encoding: 7BIT Please subscribe me to this list. Thank you! From owner-ageing@net.bio.net Tue Jul 06 23:00:00 1993 Path: biosci!bcm!cs.utexas.edu!swrinde!gatech!darwin.sura.net!wvnvms.wvnet.edu!marshall.wvnet.edu!newsmgr From: mmg@CAMIS.STANFORD.EDU (Mary Kane Goldstein) Newsgroups: bionet.molbio.ageing,bit.listserv.gerinet Subject: Message-ID: Date: 7 Jul 93 17:50:55 GMT Sender: Geriatric Health Care Discussion Group Reply-To: Geriatric Health Care Discussion Group Lines: 4 Xref: biosci bionet.molbio.ageing:455 To: IN%"NEWSMGR@muvms6.wvnet.edu" "Marshall University" CC: Subj: Return-path: <@UBVM.CC.BUFFALO.EDU:owner-gerinet@UBVM.CC.BUFFALO.EDU> Return-path: mmg <@UBVM.CC.BUFFALO.EDU:mmg@CAMIS.STANFORD.EDU> In-reply-to: Your message <9307071017.AB08171@CAMIS.Stanford.EDU> of Tue,6 Jul 1993 13:30:27 CDT To: Marshall University Content-type: TEXT/plain; charset=US-ASCII Content-transfer-encoding: 7BIT X-To: Geriatric Health Care Discussion Group Please send information on the list - the intended material and audience, and how to join if one wants. thank you. Mary Goldstein From owner-ageing@net.bio.net Wed Jul 07 23:00:00 1993 Path: biosci!daresbury!doc.ic.ac.uk!pipex!uunet!europa.eng.gtefsd.com!darwin.sura.net!wvnvms.wvnet.edu!marshall.wvnet.edu!newsmgr From: kristoff@NET.BIO.NET (David Kristofferson) Newsgroups: bionet.molbio.ageing,bit.listserv.gerinet Subject: RE: Message-ID: <9307080138.AA00235@net.bio.net> Date: 8 Jul 93 01:38:59 GMT References: Sender: Geriatric Health Care Discussion Group Reply-To: Geriatric Health Care Discussion Group Lines: 373 Xref: biosci bionet.molbio.ageing:456 To: IN%"NEWSMGR@muvms6.wvnet.edu" "Marshall University" CC: Return-path: <@UBVM.CC.BUFFALO.EDU:owner-gerinet@UBVM.CC.BUFFALO.EDU> Return-path: kristoff<@UBVM.CC.BUFFALO.EDU,@CMSA.BERKELEY.EDU:kristoff@NET.BIO.NET> To: Marshall University Content-transfer-encoding: 7BIT In bionet.molbio.ageing you write: >Please send information on the list - the intended material and audience, and >how to join if one wants. thank you. >Mary Goldstein Our instruction sheet follows. If you can not use news software and therefore need to subscribe by e-mail, please send your newsgroup selection(s) from the list below to biosci@net.bio.net. Thank you for your interest in the BIOSCI newsgroups. ---------------------------------------------------------------------- THE BIOSCI ELECTRONIC NEWSGROUP NETWORK INFORMATION SHEET ---------------------------------------------------------------------- This is the BIOSCI information sheet for the Americas and Pacific Rim countries. If you are located in Europe, Africa, or Central Asia, please request that version of the BIOSCI information sheet by sending e-mail to the Internet address: biosci@net.bio.net. New users of BIOSCI/bionet may want to read the "Frequently Asked Questions" or "FAQ" sheet for BIOSCI. The FAQ provides details on how to participate in these forums and is available for anonymous FTP from net.bio.net [134.172.2.69] in pub/BIOSCI/biosci.FAQ. 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For waismail instructions, send the word help in a message to waismail@net.bio.net. Please leave the Subject: line of your message blank. List of BIOSCI Newsgroups ------------------------- NEWSGROUP NAME TOPIC -------------- ----- ACEDB-SOFT Discussions by users and developers of genome databases using the ACEDB software. AGEING Discussions about ageing research AGROFORESTRY Discussions about agroforestry research ARABIDOPSIS Newsgroup for the Arabidopsis Genome Project BIOFORUM Discussions about biological topics for which there is not yet a dedicated newsgroup BIOLOGICAL-INFORMATION- THEORY-AND-CHOWDER-SOCIETY Applications of information theory to biology BIONAUTS Question/answer forum for help using electronic networks, locating e-mail addresses, etc. BIONEWS ** General announcements of widespread interest to biologists BIO-JOURNALS ** Tables of Contents of biological journals BIO-MATRIX Applications of computers to biological databases BIO-SOFTWARE Information on software for the biological sciences CHROMOSOMES Discussions about mapping and sequencing of eucaryote chromosomes COMPUTATIONAL-BIOLOGY ** Mathematical and computer applications in biology DROSOPHILA Discussions about biological research on Drosophila EMBL-DATABANK Messages to and from the EMBL database staff EMPLOYMENT Job opportunities in biology (see BIOSCI FAQ *before* posting commercial job openings) GDB Messages to and from the Genome Data Bank staff GENBANK-BB Messages to and from the GenBank database staff GENETIC-LINKAGE Newsgroup for genetic linkage analysis HIV-MOLECULAR-BIOLOGY Discussions about the molecular biology of HIV HUMAN-GENOME-PROGRAM NIH-sponsored newsgroup on human genome issues IMMUNOLOGY Discussions about research in immunology INFO-GCG Discussions about the GCG sequence analysis software JOURNAL-NOTES Practical advice on dealing with professional journals METHODS-AND-REAGENTS Requests for information and lab reagents MOLECULAR-EVOLUTION Discussions about research in molecular evolution NEUROSCIENCE Discussions about research in the neurosciences N2-FIXATION Discussion about biological nitrogen fixation PHOTOSYNTHESIS Discussions about photosynthesis research PLANT-BIOLOGY Discussions about research in plant biology POPULATION-BIOLOGY Discussions about research in population biology PROTEIN-ANALYSIS Discussions about research on proteins and messages for the PIR and SWISS-PROT databank staffs. PROTEIN-CRYSTALLOGRAPHY Discussion about crystallography of macromolecules and messages for the PDB staff RAPD Discussions about Randomly Amplified Polymorphic DNA SCIENCE-RESOURCES ** Information from/about scientific funding agencies TROPICAL-BIOLOGY Discussions about research in tropical biology VIROLOGY Discussions about research in virology WOMEN-IN-BIOLOGY Discussions about issues concerning women biologists YEAST Discussions about the molecular biology and genetics of yeast ** Note that newsgroups flagged with ** are moderated, i.e., postings are directed to a moderator (editor) who later forwards messages (possibly edited or condensed) to the newsgroup. Posting Messages to Newsgroups ------------------------------ The lists below include the addresses for posting messages and also the names of the corresponding UNIX USENET newsgroups. Messages can either be posted into the USENET newsgroups using "postnews" or similar software or they can be submitted by electronic mail to the mailing addresses given below. In most cases, messages are posted directly to the newsgroups without editorial intervention. USENET users who use the "postnews" or similar software on their local computer should be sure to set the message distribution to "world" or "bionet" or else your message may not be distributed beyond your local computer. USENET newsgroups are read using, e.g., the "readnews," "rn," or "vnews" software on UNIX systems. USENET news software is in the public domain and is available for most UNIX systems. A public domain USENET news software package named ANU-NEWS is also available for VAX/VMS systems. Your local BIOSCI node can point you towards acquiring the software for use on your computer system. Those who use e-mail to post messages should send their mail to the following Internet addresses in the USA: NEWSGROUP NAME Mailing Address -------------- ---------------- ACEDB-SOFT acedb@net.bio.net AGEING ageing@net.bio.net AGROFORESTRY ag-forst@net.bio.net ARABIDOPSIS arab-gen@net.bio.net BIOFORUM bioforum@net.bio.net BIO-INFORMATION-THEORY + bio-info@net.bio.net BIONAUTS bio-naut@net.bio.net BIONEWS ** bionews@net.bio.net BIO-JOURNALS ** bio-jrnl@net.bio.net BIO-MATRIX biomatrx@net.bio.net BIO-SOFTWARE bio-soft@net.bio.net CHROMOSOMES biochrom@net.bio.net COMPUTATIONAL-BIOLOGY ** comp-bio@net.bio.net DROSOPHILA dros@net.bio.net EMBL-DATABANK embl-db@net.bio.net EMPLOYMENT biojobs@net.bio.net GDB gdb@net.bio.net GENBANK-BB genbankb@net.bio.net GENETIC-LINKAGE gen-link@net.bio.net HIV-MOLECULAR-BIOLOGY hiv-biol@net.bio.net HUMAN-GENOME-PROGRAM gnome-pr@net.bio.net IMMUNOLOGY immuno@net.bio.net INFO-GCG info-gcg@net.bio.net JOURNAL-NOTES jrnlnote@net.bio.net METHODS-AND-REAGENTS methods@net.bio.net MOLECULAR-EVOLUTION mol-evol@net.bio.net NEUROSCIENCE neur-sci@net.bio.net N2-FIXATION n2fix@net.bio.net PHOTOSYNTHESIS photosyn@net.bio.net PLANT-BIOLOGY plantbio@net.bio.net POPULATION-BIOLOGY pop-bio@net.bio.net PROTEIN-ANALYSIS proteins@net.bio.net PROTEIN-CRYSTALLOGRAPHY xtal-log@net.bio.net RAPD rapd@net.bio.net SCIENCE-RESOURCES ** sci-res@net.bio.net TROPICAL-BIOLOGY trop-bio@net.bio.net VIROLOGY virology@net.bio.net WOMEN-IN-BIOLOGY womenbio@net.bio.net YEAST yeast@net.bio.net + full name is BIOLOGICAL-INFORMATION-THEORY-AND-CHOWDER-SOCIETY ** Note that newsgroups flagged with ** are moderated, i.e., postings are directed to a moderator (editor) who later forwards messages (possibly edited or condensed) to the newsgroup. List of USENET newsgroups ------------------------- BIOSCI messages are distributed on the following USENET newsgroups in the "bionet" heirarchy. Contents of the USENET newsgroups and the e-mail distributions listed above are the same, i.e., messages sent in by e-mail are also forwarded to USENET and messages posted to USENET newsgroups are also distributed to e-mail subscribers. NEWSGROUP NAME USENET Newsgroup Name -------------- --------------------- ACEDB-SOFT bionet.software.acedb AGEING bionet.molbio.ageing AGROFORESTRY bionet.agroforestry ARABIDOPSIS bionet.genome.arabidopsis BIOFORUM bionet.general BIO-INFORMATION-THEORY + bionet.info-theory BIONAUTS bionet.users.addresses BIONEWS ** bionet.announce BIO-JOURNALS ** bionet.journals.contents BIO-MATRIX bionet.molbio.bio-matrix BIO-SOFTWARE bionet.software CHROMOSOMES bionet.genome.chromosomes COMPUTATIONAL-BIOLOGY ** bionet.biology.computational DROSOPHILA bionet.drosophila EMBL-DATABANK bionet.molbio.embldatabank EMPLOYMENT bionet.jobs GDB bionet.molbio.gdb GENBANK-BB bionet.molbio.genbank GENETIC-LINKAGE bionet.molbio.gene-linkage HIV-MOLECULAR-BIOLOGY bionet.molbio.hiv HUMAN-GENOME-PROGRAM bionet.molbio.genome-program IMMUNOLOGY bionet.immunology INFO-GCG bionet.software.gcg JOURNAL-NOTES bionet.journals.note METHODS-AND-REAGENTS bionet.molbio.methds-reagnts MOLECULAR-EVOLUTION bionet.molbio.evolution NEUROSCIENCE bionet.neuroscience N2-FIXATION bionet.biology.n2-fixation PHOTOSYNTHESIS bionet.photosynthesis PLANT-BIOLOGY bionet.plants POPULATION-BIOLOGY bionet.population-bio PROTEIN-ANALYSIS bionet.molbio.proteins PROTEIN-CRYSTALLOGRAPHY bionet.xtallography RAPD bionet.molbio.rapd SCIENCE-RESOURCES ** bionet.sci-resources TROPICAL-BIOLOGY bionet.biology.tropical VIROLOGY bionet.virology WOMEN-IN-BIOLOGY bionet.women-in-bio YEAST bionet.molbio.yeast + full name is BIOLOGICAL-INFORMATION-THEORY-AND-CHOWDER-SOCIETY ** Note that newsgroups flagged with ** are moderated, i.e., postings are directed to a moderator (editor) who later forwards messages (possibly edited or condensed) to the newsgroup. BIOSCI "prototype" newsgroups ----------------------------- To assist areas of research in developing their own electronic communication forums, BIOSCI at net.bio.net will set up on request a mailing list *without* an associated USENET newsgroup. The mailing list is created only at net.bio.net, the U.S. BIOSCI node, and all subscription requests must be sent to biosci@net.bio.net regardless of one's geographical location. There is no charge for this or any other BIOSCI service, as usual. This procedure waives the rule that requires each new newsgroup proposal to be put to a vote of the readership first (see the BIOSCI FAQ, mentioned at the beginning of this document, for details on creating new full-fledged newsgroups and prototype newsgroups). Each mailing list ("prototype newsgroup") must have a scientist volunteer to serve as its discussion leader. The prototype newsgroup has six months to build up its readership after which time it is put out for a vote for full newsgroup status (i.e., to have both a mailing list *and* parallel USENET newsgroup created at both BIOSCI nodes in the U.S. and U.K.). If you are interested in establishing such a forum for your research specialty, please contact biosci@net.bio.net. The current prototype newsgroups are listed below. Please send subscription requests to biosci@net.bio.net and NOT to the newsgroup posting addresses. Prototype newsgroups are *not* archived, so please be sure to save any messages that you may want to refer to again. Posting Address Purpose --------------- ------- btk-mca@net.bio.net Discussions about biothermal kinetics pep-libs@net.bio.net Discussion on generation and use of peptide molecular repertoires displayed on phage or prepared as synthetic peptide combinatorial libraries. yac@net.bio.net Dicussions about yeast artificial chromosomes FURTHER QUESTIONS??? Please address them to biosci@net.bio.net. From owner-ageing@net.bio.net Sun Jul 11 23:00:00 1993 Path: biosci!uwm.edu!ux1.cso.uiuc.edu!howland.reston.ans.net!usc!usc!not-for-mail From: jdevlin@pollux.usc.edu (Joseph Devlin) Newsgroups: bionet.molbio.ageing,bionet.neuroscience Subject: Alzheimer's and Benadryl Message-ID: <21sgju$b44@pollux.usc.edu> Date: 12 Jul 93 20:12:46 GMT Sender: jdevlin@pollux.usc.edu Organization: University of Southern California, Los Angeles, CA Lines: 17 Xref: biosci bionet.molbio.ageing:457 bionet.neuroscience:1460 NNTP-Posting-Host: pollux.usc.edu Last weekend a friend mentioned hearing a radio report claiming that prolonged use of the OTC drug Benadryl (sp?) was correlated with the likihood of getting Alzheimer's disease...Alledgedly the report was from a hospital based in Philadelphia but my friend thought it was not UPenn. Did anyone hear/read anything about this? I really like a reference if this is a true study. Thanks much! - Joe ************************************************************************* Joseph Devlin * email: jdevlin@pollux.usc.edu University of Southern California * Department of Computer Science * "The axon doesn't think. Los Angeles, CA 90089 * It just ax." George Bishop ************************************************************************* From owner-ageing@net.bio.net Wed Jul 14 23:00:00 1993 Path: biosci!uwm.edu!cs.utexas.edu!swrinde!gatech!europa.eng.gtefsd.com!darwin.sura.net!wvnvms.wvnet.edu!marshall.wvnet.edu!newsmgr From: HECKERSL@TEMPLEVM.BITNET (slh) Newsgroups: bionet.molbio.ageing,bit.listserv.gerinet Subject: subscription Message-ID: Date: 15 Jul 93 12:37:01 GMT Sender: Geriatric Health Care Discussion Group Reply-To: Geriatric Health Care Discussion Group Lines: 2 Xref: biosci bionet.molbio.ageing:458 To: IN%"NEWSMGR@muvms6.wvnet.edu" "Marshall University" CC: Return-path: <@UBVM.CC.BUFFALO.EDU:owner-gerinet@UBVM.CC.BUFFALO.EDU> Return-path: HECKERSL<@UBVM.CC.BUFFALO.EDU,@VM.TEMPLE.EDU:HECKERSL@VM.TEMPLE.EDU> To: Marshall University Content-transfer-encoding: 7BIT please enter my subscription From owner-ageing@net.bio.net Mon Jul 19 23:00:00 1993 Path: biosci!bcm!cs.utexas.edu!swrinde!gatech!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!wvnvms.wvnet.edu!marshall.wvnet.edu!newsmgr From: mwitten@HERMES.CHPC.UTEXAS.EDU Newsgroups: bionet.molbio.ageing,bit.listserv.gerinet Subject: COMPUTATIONAL HEALTH (long) Message-ID: <9307192314.AA10773@morpheus.chpc.utexas.edu> Date: 19 Jul 93 23:14:43 GMT Sender: Geriatric Health Care Discussion Group Reply-To: Geriatric Health Care Discussion Group Lines: 339 Xref: biosci bionet.molbio.ageing:459 To: IN%"NEWSMGR@muvms6.wvnet.edu" "Marshall University" CC: Return-path: <@UBVM.CC.BUFFALO.EDU:owner-gerinet@UBVM.CC.BUFFALO.EDU> Return-path: mwitten<@UBVM.CC.BUFFALO.EDU,@UTHERMES.BITNET:mwitten@HERMES.CHPC.UTEXAS.EDU> To: Marshall University Content-transfer-encoding: 7BIT X-To: GERINET@ubvm.bitnet Comments: W: FROM field duplicated. Last occurrence was retained. Preliminary Announcement FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE, PUBLIC HEALTH AND BIOTECHNOLOGY 24-28 April 1994 Hyatt Regency Hotel Austin, Texas ----- (Feel Free To Cross Post This Announcement) ---- 1.0 CONFERENCE OVERVIEW: With increasing frequency, computational sciences are being exploited as a means with which to investigate biomedical processes at all levels of complexity; from molecular to systemic to demographic. Computational instruments are now used, not only as exploratory tools but also as diagnostic and prognostic tools. The appearance of high performance computing environments has, to a great extent, removed the problem of increasing the biological reality of themathematical models. For the first time in the historyof the field, practical biological reality is finally within the grasp of the biomedical modeler. Mathematical complexity is no longer as serious an issue as speeds of computation are now of the order necessary to allow extremely large and complex computational models to be analyzed. Large memory machines are now routinely available. Additionally, high speed, efficient, highly optimized numerical algorithms are under constant development. As these algorithms are understood and improved upon, many of them are transferred from software implementation to an implementation in the hardware itself; thereby further enhancing the available computational speed of current hardware. The purpose of this congress is to bring together a transdisciplinary group of researchers in medicine, public health, computer science, mathematics, nursing, veterinary medicine, ecology, allied health, as well as numerous otherdisciplines, for the purposes of examining the grand challenge problems of the next decades. This will be a definitive meeting in that it will be the first World Congress of its type and will be held as a followup tothe very well received Workshop On High Performance Computing In The Life Sciences and Medicine held by the University of Texas System Center For High Performance Computing in 1990. Young scientists are encouraged to attend and to present their work in this increasingly interesting discipline. Funding is being solicited from NSF, NIH, DOE, Darpa, EPA, and private foundations, as well as other sources to assist in travel support and in the offsetting of expenses for those unable to attend otherwise. Papers, poster presentations, tutorials, focussed topic workshops, birds of a feather groups, demonstrations, and other suggestions are also solicited. 2.0 CONFERENCE SCOPE AND TOPIC AREAS: The Congress hasa broad scope. If you are not sure as to whether or not your subject fits the Congress scope, contact the conference organizers at one of the addresses below. Subject areas include but are not limited to: *Visualization/Sonification --- medical imaging --- molecular visualization as a clinical research tool --- simulation visualization --- microscopy --- visualization as applied to problems arising in computational molecular biology and genetics or other non-traditional disciplines *Computational Molecular Biology and Genetics --- computational ramifications of clinical needs in the Human Genome, Plant Genome, and Animal Genome Projects --- computational and grand challenge problems in molecular biology and genetics --- algorithms and methodologies --- issues of multiple datatype databases *Computational Pharmacology, Pharmacodynamics, Drug Design *Computational Chemistry as Applied to Clinical Issues *Computational Cell Biology, Physiology, and Metabolism --- Single cell metabolic models (red blood cell) --- Cancer models --- Transport models --- Single cell interaction with external factors models (laser, ultrasound, electrical stimulus) *Computational Physiology and Metabolism --- Renal System --- Cardiovascular dynamics --- Liver function --- Pulmonary dynamics --- Auditory function, coclear dynamics, hearing --- Reproductive modeling: ovarian dynamics, reproductive ecotoxicology, modeling the hormonal cycle --- Metabolic Databases and metabolic models *Computational Demography, Epidemiology, and Statistics/Biostatistics --- Classical demographic, epidemiologic, and biostatistical modeling --- Modeling of the role of culture, poverty, and other sociological issues as they impact healthcare *Computational Disease Modeling --- AIDS --- TB --- Influenza --- Statistical Population Genetics Of Disease Processes --- Other *Computational Biofluids --- Blood flow --- Sperm dynamics --- Modeling of arteriosclerosis and related processes *Computational Dentistry, Orthodontics, and Prosthetics *Computational Veterinary Medicine --- Computational issues in modeling non-human dynamics such as equine, feline, canine dynamics (physiological/biomechanical) *Computational Allied Health Sciences --- Physical Therapy --- Neuromusic Therapy --- Resiratory Therapy *Computational Radiology --- Dose modeling --- Treatment planning *Computational Surgery --- Simulation of surgical procedures in VR worlds --- Surgical simulation as a precursor to surgical intervention *Computational Cardiology *Computational Nursing *Computational Models In Chiropractice *Computational Neurobiology and Neurophysiology --- Brain modeling --- Single neuron models --- Neural nets and clinical applications --- Neurophysiological dynamics --- Neurotransmitter modeling --- Neurological disorder modeling (Alzheimers Disease, for example) *Computational Models of Psychiatric and Psychological Processes *Computational Biomechanics --- Bone Modeling --- Joint Modeling *Computational Models of Non-tradional Medicine --- Acupuncture --- Other *Computational Issues In Medical Instrumentation Design and Simulation --- Scanner Design --- Optical Instrumentation *Ethical issues arising in the use of computational technology in medical diagnosis and simulation *The role of alternate reality methodologies and high performance environments in the medical and public health disciplines *Issues in the use of high performance computing environments in the teaching of health science curricula *The role of high performance environments for the handling of large medical datasets (high performance storage environments, high performance networking, high performance medical records manipulation and management, metadata structures and definitions) *Federal and private support for transdisciplinary research in computational medicine and public health 3.0 CONFERENCE COMMITTEE *CONFERENCE CHAIR: Matthew Witten, UT System Center For High Performance Computing, Austin, Texas m.witten@chpc.utexas.edu *CONFERENCE DIRECTORATE: Regina Monaco, Mt. Sinai Medical Center * Dan Davison, University of Houston * Chris Johnson, University of Utah * Lisa Fauci, Tulane University * Daniel Zelterman, University of Minnesota Minneapolis * James Hyman, Los Alamos National Laboratory * Richard Hart, Tulane University * Dennis Duke, SCRI-Florida State University * Sharon Meintz, University of Nevada Los Vegas * Dean Sittig, Vanderbilt University * Dick Tsur, UT System CHPC * Dan Deerfield, Pittsburgh Supercomputing Center * Istvan Gyori, Szeged University School of Medicine Computing Center * Don Fussell, University of Texas at Austin * Ken Goodman, University Of Miami School of Medicine * Martin Hugh-Jones, Louisiana State University * Stuart Zimmerman, MD Anderson Cancer Research Center * John Wooley, DOE * Sylvia Spengler, University of California Berkeley, Robert Blystone, Trinity University Additional conference directorate members are being added and will be updated on the anonymous ftp list as they agree. 4.0 CONTACTING THE CONFERENCE COMMITTEE: To contact the congress organizers for any reason use any of the following pathways: ELECTRONIC MAIL - compmed94@chpc.utexas.edu FAX (USA) - (512) 471-2445 PHONE (USA) - (512) 471-2472 GOPHER:log into the University of Texas System-CHPC select the Computational Medicine and Allied Health menu choice ANONYMOUS FTP: ftp.chpc.utexas.edu cd /pub/compmed94 POSTAL: Compmed 1994 University of Texas System CHPC Balcones Research Center, 1.154CMS 10100 Burnet Road Austin, Texas 78758-4497 5.0 SUBMISSION PROCEDURES: Authors must submit 5 copies of a single-page 50-100 word abstract clearly discussing the topic of their presentation. In addition, authors must clearly state their choice of poster, contributed paper, tutorial, exhibit, focussed workshop or birds of a feather group along with a discussion of their presentation. Abstracts will be published as part of the preliminary conference material. To notify the congress organizing committee that you would like to participate and to be put on the congress mailing list, please fill out and return the form that follows this announcement. You may use any of the contact methods above. If you wish to organize a contributed paper session, tutorial session,focussed workshop, or birds of a feather group, please contact the conference director at mwitten@chpc.utexas.edu *CONFERENCE DEADLINES: The following deadlines should be noted: 1 October 1993 - Notification of interest in participation and/or intent to organize a special session 1 November 1993 - Abstracts for talks/posters/ workshops/birds of a feather sessions/demonstrations 15 January 1994 - Notification of acceptance of abstract 15 February 1994 - Application for financial aid 6.0 CONFERENCE PRELIMINARY DETAILS AND ENVIRONMENT LOCATION: Hyatt Regency Hotel, Austin, Texas, USA DATES: 24-28 April 1994 The 1st World Congress On Computational Medicine, Public Health, and Biotechnology will be held at the Hyatt Regency Hotel, Austin, Texas located in downtown Austin. The hotel is approximately 15 minutes from Robert Meuller Airport. Austin, the state capital, is renouned for its natural hill-country beauty and an active cultural scence. Several hiking and jogging trails are within walking distance of the hotel, as well as opportunities for a variety of aquatic sports. Live bands perform in various nightclubs around the city and at night spots along Sixth Street, offering a range of jazz, blues, country/Western, reggae, swing, and rock music. Day temperatures will be in the 80-90(degree F) range and fairly humid. Exhibitor and vendor presentations are also being planned. 7.0 CONFERENCE ENDORSEMENTS AND SPONSORSHIPS: Numerous potential academic sponsors have been contacted. Currently negotiations are underway for sponsorship with SIAM, AMS, MAA, IEEE, FASEB, and IMACS. Additionally AMA and ANA continuing medical education support is beging sought. Information will be updated regularly on the anonymous ftp site for the conference (see above). ================== INTENT TO PARTICIPATE ============= First Name: Middle Initial (if available): Family Name: Your Professional Title: [ ]Dr. [ ]Professor [ ]Mr. [ ]Mrs. [ ]Ms. [ ]Other:__________________ Office Phone (desk): Office Phone (message): Home/Evening Phone (for emergency contact): Fax: Electronic Mail (Bitnet): Electronic Mail (Internet): Postal Address: Institution or Center: Building Code: Mail Stop: Street Address1: Street Address2: City: State: Country: Zip or Country Code: Please list your three major interest areas: Interest1: Interest2: Interest3: ===================================================== From owner-ageing@net.bio.net Tue Jul 27 23:00:00 1993 Path: biosci!GRAY.CSCWC.PIMA.EDU!tcovingt From: tcovingt@GRAY.CSCWC.PIMA.EDU (Tatiana Covington) Newsgroups: bionet.molbio.ageing Subject: (none) Message-ID: <9307282241.AA20432@gray.cscwc.pima.edu> Date: 28 Jul 93 22:41:32 GMT Sender: daemon@net.bio.net Distribution: bionet Lines: 1 quit From owner-ageing@net.bio.net Thu Jul 29 23:00:00 1993 Path: biosci!daresbury!doc.ic.ac.uk!warwick!pipex!uunet!dziuxsolim.rutgers.edu!trident.usacs.rutgers.edu!jaslin From: jaslin@trident.usacs.rutgers.edu (Jasper) Newsgroups: bionet.molbio.ageing,bionet.neuroscience Subject: Re: Alzheimer's and Benadryl Message-ID: Date: 30 Jul 93 21:58:33 GMT References: <21sgju$b44@pollux.usc.edu> Followup-To: bionet.molbio.ageing Organization: Rutgers Univ., New Brunswick, N.J. Lines: 8 Xref: biosci bionet.molbio.ageing:461 bionet.neuroscience:1502 jdevlin@pollux.usc.edu (Joseph Devlin) writes: > Last weekend a friend mentioned hearing a radio report claiming >that prolonged use of the OTC drug Benadryl (sp?) was correlated >with the likihood of getting Alzheimer's disease...Alledgedly the over-the-counter antihistamine? that's scary. i have a friend who practically eats the stuff. (he has skin allergies or something).