From owner-ageing@net.bio.net Wed Apr 02 23:00:00 1997 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.molbio.ageing Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 3 Apr 1997 02:00:12 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 239 Sender: daemon@net.bio.net Distribution: world Message-ID: <199704031000.CAA17488@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net From owner-ageing@net.bio.net Fri Apr 04 23:00:00 1997 Path: biosci!agate!howland.erols.net!vixen.cso.uiuc.edu!uwm.edu!news.cse.psu.edu!news.ece.nwu.edu!newsfeed.acns.nwu.edu!news.acns.nwu.edu!pchen From: pchen@nwu.edu (Jun Peng) Newsgroups: bionet.molbio.ageing Subject: Bullous pemphigoid Date: Fri, 04 Apr 1997 12:20:43 -0600 Organization: Northwestern University Lines: 7 Message-ID: NNTP-Posting-Host: 165.124.123.23 Mime-Version: 1.0 Content-Type: text/plain; charset=ISO-8859-1 Content-Transfer-Encoding: 8bit X-Newsreader: Yet Another NewsWatcher 2.4.0 Bullous pemphigoid is a disease of aging. It has an average disease onset of 60 years old. I would like to get a statistic number of BP's percentage in the population. Where should I look for it? Please e-mail me. Thanks. JP From owner-ageing@net.bio.net Sat Apr 05 23:00:00 1997 Path: biosci!rutgers.rutgers.edu!uwm.edu!newsfeeds.sol.net!worldnet.att.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news-peer.sprintlink.net!howland.erols.net!torn!newshost.uwo.ca!usenet From: Charles Carter Newsgroups: bionet.molbio.ageing Subject: (no subject) Date: 6 Apr 1997 00:56:57 GMT Organization: (UWO, London, Canada) Lines: 8 Message-ID: <5i6scp$nce@falcon.ccs.uwo.ca> NNTP-Posting-Host: ts7-13.slip.uwo.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Authenticated: ccarter2@ts7-13.slip.uwo.ca X-Mailer: Mozilla 1.22 (Windows; I; 16bit) Does anyone want to talk about the biochemical implications of having a faulty recQ helicase, such as in the premature aging disease Werner Syndrome (for which the WRN gene has recently been cloned)? Chuck From owner-ageing@net.bio.net Sun Apr 06 23:00:00 1997 Path: biosci!rutgers.rutgers.edu!gatech!europa.chnt.gtegsc.com!boingo.amil.jhu.edu!blaze.cs.jhu.edu!news.jhu.edu!news From: Robert Georgantas Newsgroups: bionet.molbio.ageing Subject: BioScience Information Date: Mon, 07 Apr 1997 16:43:20 +0000 Organization: Johns Hopkins University Lines: 65 Message-ID: <3349241B.2BD6@welchlink.welch.jhu.edu> Reply-To: rgeorgan@welchlink.welch.jhu.edu NNTP-Posting-Host: 162.129.38.137 Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Mailer: Mozilla 3.01Gold (Macintosh; I; PPC) Announcing the SCIENCE GUIDE. http://www.scienceguide.com A New Internet Directory and Information Service run by Scientists and Physicians for Scientists and Physicians. After visiting the Guide, If you have any suggestion for making the Guide better please let us know. (webmaster@scienceguide.com) The Science Guide consists of a number of different sections designed to help the scientist and physician find information on the internet and to sponsor communication between those interested in science: NEWS SECTION Every day the Science Guide compiles medical and research news from national news sources around the net. Most of the news articles are concerned with medicine, bioscience, and physics, but all other sciences from agriculture to zoology are commonly included. News sources currently listed include: CNN, EurekAlert, HMS Beagle, MSNBC Sci-Tech, Science Magazine’s ScienceNow, CBS Space News, USA Today, The Albuquerque Journal, Scientific American Web Weekly, The Why Files, Discover Magazine, Scientific American, Smithsonian Magazine, and the Technology Review. The news pages also list links to news sources not compiled within the News site. We are currently working on adding a number of other sources to the site to make it even more useful. To make getting science news even easier, we send out a DAILY NEWS EMAILER listing the articles which have been compiled on our site. Anyone can subscribe to the Emailer by sending an email to news@scienceguide.com with the message “Subscribe” DIRECTORY OF USENET NEWS GROUPS and DISCUSSION LISTS The Directory of Usenet and Discussion Groups is compiled quarterly from different sources around the net to provide the scientist and those interested in science easy access to these invaluable sources of discourse and information. We are currently working on finding the proper subscription method for each of the discussion lists. This is taking a bit longer that we thought so please pardon our dust. The Usenet portions of this section are complete. ON-LINE JOURNAL HYPERLINK SECTION The Journals Section contains links to peer reviewed scientific journals on the Internet. Each listing clearly indicates whether the journal provides only the table of contents, TOC with abstracts, or the full text of the journal EMPLOYMENT SECTION The Jobs and Positions Section contains hyperlinks to the best Scientific Employment Databases and Classifieds on the net. GRANTS and FUNDING SECTION The funding section contains links to the best funding and grant databases on the Internet, making it very easy for scientists to quickly find funding opportunities. The featured site of the section is “The Community of Science,” a Johns Hopkins service designed to help scientists find and continue funding. From owner-ageing@net.bio.net Tue Apr 08 23:00:00 1997 Path: biosci!agate!howland.erols.net!europa.clark.net!news.msfc.nasa.gov!info.uah.edu!its1.ocs.lsu.edu!grant From: grant@bit.csc.lsu.edu (Kevin Paul Grant) Newsgroups: bionet.molbio.ageing Subject: Hair loss, DHT, green tea and shampoo Date: 9 Apr 1997 11:00:30 GMT Organization: Department of Computer Science, LSU, Baton Rouge Lines: 26 Message-ID: <5ifsse$m7m$1@its1.ocs.lsu.edu> NNTP-Posting-Host: bit.csc.lsu.edu This may be a crazy idea, but... One of the major factors (perhaps THE major factor) in male hair loss due to aging is increased quantities of DHT that hang around doing damage to hair producing cells (or perhaps it's increased susceptibility to DHT related damage). In any event, there are herbs that decrease the body's rate of conversion of T to DHT (saw palmetto, green tea). My understanding is that while some of the conversion takes place internally a significant amount of it takes place in skin cells, including the skin on those parts of your body where all that hair falls out. Now here's the question: Is it possible that topical application of green tea would decrease the rate of conversion of T to DHT by the skin cells so treated? If so by how much and for how long before another application is required? Could the rate of hair loss be significantly reduced by using "green tea" shampoo? Heck, with all the "bath oils" and other, smelly, bath-related stuff on the market why not just throw a few green tea-bags in the tub and soak for a while? How much hair loss is due to internally produced DHT versus DHT produced by skin cells? Thanks, Kevin From owner-ageing@net.bio.net Thu Apr 10 23:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.maxwell.syr.edu!news-peer.sprintlink.net!news.sprintlink.net!sprint!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!newsfeed.nacamar.de!news.he.net!calwebnntp!news.campus.mci.net!n-f-m From: "Jan Coetzee" Newsgroups: bionet.molbio.ageing Subject: Re: (no subject) Date: 9 Apr 1997 01:41:25 GMT Organization: CampusMCI Lines: 17 Message-ID: <01bc44a0$3b57d7c0$221166ce@hp-customer> References: <5i6scp$nce@falcon.ccs.uwo.ca> NNTP-Posting-Host: s05-pm07.atlanta.campus.mci.net X-Newsreader: Microsoft Internet News 4.70.1155 Charles Carter wrote in article <5i6scp$nce@falcon.ccs.uwo.ca>... > Does anyone want to talk about the biochemical implications of having a > faulty recQ helicase, such as in the premature aging disease Werner > Syndrome (for which the WRN gene has recently been cloned)? > > Chuck > > > > Could you give more information faulty recQ helicase? Jan(John) From owner-ageing@net.bio.net Thu Apr 10 23:00:00 1997 Path: biosci!daresbury!not-for-mail From: mjfasmb Newsgroups: bionet.molbio.ageing Subject: Ageing and methylation Date: 11 Apr 1997 11:53:24 +0100 Organization: Dept. Chem Eng - UMIST (FS1) Lines: 39 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <5il574$93f@mserv1.dl.ac.uk> X-mailer: Pegasus Mail for Windows (v2.32) MIME-Version: 1.0 Original-To: ageing@dl.ac.uk > > Jean-Pierre Issa wrote : > > I disagree with your dismissal of methylation's role in > > aging: DNA methylation patterns are reset during early > > embryogenesis. In fact, the Dolly experiment supports a > > methylation theory of aging (changes irreversible in adult > > cells but reversible in embryonal cells) over a mutational > > theory of aging (changes irreversible no matter what). > > Incidentally, there is some data suggesting that this may be > > true for some cancers as well. I'd agree that the mutational theory (by itself) is a very weak argument for ageing. However, oxidative damage has been shown to play a central role in the ageing of post-mitotic tissue and can reduce the replicative lifespan of mitotic cells. As for methylation - the question is whether changes in the methylation state of DNA occur as a consequence of ageing or actually cause the phenomenon. If such changes merely reflect altered expression patterns (?) you would expect to see them in embryonic and cancerous cell lines anyway. An added complexity is that there are different types of cellular ageing : clonal senescence (as exhibited by most mammalian cell lines), where mother and daughter inherit approx. the same age; asymmetric senescence (as exhibited by yeast), where the daughter cells age is usually reset to zero and finally temporal senescence (as occurs in post-mitotic tissue). Most people refer to `immortal' cancer cell lines - reflecting the loss of clonal senescence and the ability to propagate the cell line indefinitely. However i very much doubt whether cancer cells are truly immortal - I'd be willing to bet a months salary that such cells have merely learned to behave like their distant yeast-like ancestors and now perform asymmetric senescence. The resetting of age at embryogenesis and what occurs during `immortalisation' of a cancer cell line are two very different things. MGB X From owner-ageing@net.bio.net Thu Apr 10 23:00:00 1997 Path: biosci!rutgers.rutgers.edu!gatech!news-out.communique.net!communique!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!news-peer.sprintlink.net!news.sprintlink.net!sprint!howland.erols.net!torn!newshost.uwo.ca!usenet From: Charles Carter Newsgroups: bionet.molbio.ageing Subject: Re: (no subject) Date: 11 Apr 1997 14:47:01 GMT Organization: (UWO, London, Canada) Lines: 22 Message-ID: <5ilit5$2bh@falcon.ccs.uwo.ca> References: <5i6scp$nce@falcon.ccs.uwo.ca> <01bc44a0$3b57d7c0$221166ce@hp-customer> NNTP-Posting-Host: ts12-2.slip.uwo.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Authenticated: ccarter2@ts12-2.slip.uwo.ca X-Mailer: Mozilla 1.22 (Windows; I; 16bit) "Jan Coetzee" wrote: > >Could you give more information faulty recQ helicase? > >Jan(John) Hi, When they sequenced the Werner syndrome gene they found it had a high degree of homology to recQ helicases, such as E. coli recQ, c.elegans F18C5C and yeast Sgs1. A mutated helicase could lower the expression of gene products that various tissues would need high concentrations at certain times. This would eventually cause all of the Werner symptoms including graying hair, osteoporosis, artherosclerosis, cataracts, diabetes, sarcomas etc. Suggested reading: Epstein, C.J. et al (1996) Werner Syndrome: entering the helicase era. Bioessays, Vol 18 no 12: 1025-1027. Chuck From owner-ageing@net.bio.net Sun Apr 13 23:00:00 1997 Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ais.net!ameritech.net!uunet!in3.uu.net!132.205.106.4!newsflash.concordia.ca!canopus.cc.umanitoba.ca!mongol.sasknet.sk.ca!news.agtac.net!news.cadvision.com!usenet From: Josh Christianson Newsgroups: bionet.molbio.ageing Subject: Molecular Processes of Ageing Date: Sun, 13 Apr 1997 13:34:40 -0600 Organization: CADVision Development Corp. Lines: 8 Message-ID: <33513550.38FC@cadvision.com> NNTP-Posting-Host: ts65ip69.cadvision.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01 (Win95; I) Hi, I am a grade 12 student from Beiseker, Alberta and my Bio teacher gave me an assignment to go on the internet and find out as much as I can on the molecular processes of Ageing, so if anyone here could help me out by giving me info. on the subject or telling me what sites contain info. on this subject, it would be much appreciated. Josh Christianson From owner-ageing@net.bio.net Sun Apr 13 23:00:00 1997 Path: biosci!bloom-beacon.mit.edu!howland.erols.net!cs.utexas.edu!news.tamu.edu!news From: Dawn Newsgroups: bionet.molbio.ageing Subject: Re: Molecular Processes of Ageing Date: Mon, 14 Apr 1997 17:02:14 -0500 Organization: Texas A&M Univ., College of Medicine, Dept of Medical Biochemistry and Genetics Lines: 26 Message-ID: <3352A966.231B@bigfoot.com> References: <33513550.38FC@cadvision.com> Reply-To: DawnC@bigfoot.com NNTP-Posting-Host: modem-0757.rns.tamu.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit NNTP-Posting-Date: 14 Apr 1997 22:00:32 GMT X-Mailer: Mozilla 3.0 (Win95; I) To: Josh Christianson Here are a few: http://www.mednwh.unimelb.edu.au/ http://www.afar.org/ http://www.hookup.net/mall/aging/agesit59.html http://www.apopnet.com/apoptosis/ http://www.bio.com/companies/geron.html Josh Christianson wrote: > > Hi, > I am a grade 12 student from Beiseker, Alberta and my Bio teacher gave > me an assignment to go on the internet and find out as much as I can on > the molecular processes of Ageing, so if anyone here could help me out > by giving me info. on the subject or telling me what sites contain info. > on this subject, it would be much appreciated. > > Josh Christianson -- -Dawn- Time is the best teacher. Unfortunately, it kills all of its students. The Chako Rescue Association for the American Pit Bull Terrier http://members.tripod.com/~DawnC From owner-ageing@net.bio.net Thu Apr 17 23:00:00 1997 Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!feed1.news.erols.com!howland.erols.net!vixen.cso.uiuc.edu!ais.net!uunet!in1.uu.net!161.142.201.20!news2.jaring.my!usenet From: "LU ZEN HUAT" Newsgroups: bionet.molbio.ageing Subject: Graduate Studies in US Date: 18 Apr 1997 18:40:24 GMT Organization: LU'S ENGINEERING SND BHD Lines: 13 Message-ID: <01bc3f94$9e6d3c80$32738ea1@luzc> NNTP-Posting-Host: j36.ptl38.jaring.my X-Newsreader: Microsoft Internet News 4.70.1155 Can somebody tell me where is the best place (on the Internet, perhaps) for me to search for information on Graduate Studies in USA, especially those related to PhD studentship. I'm looking for a PhD position in Biomedical or Agricultural Biotechnology research. If you are interested to look at my CV, you can find it in my home page which is located at http://www.strath.ac.uk/~ddp95120 or htpp://www.geocities.com/CapeCanaveral/Lab/2073 Thank you! From owner-ageing@net.bio.net Thu Apr 17 23:00:00 1997 Path: biosci!FREENET.TORONTO.ON.CA!bk772 From: bk772@FREENET.TORONTO.ON.CA (Dmitri Chamchad) Newsgroups: bionet.molbio.ageing Subject: Residency programs in Pathology Date: 18 Apr 1997 12:45:43 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 148 Sender: daemon@net.bio.net Distribution: world Message-ID: References: <01bc3f94$9e6d3c80$32738ea1@luzc> Reply-To: Dmitri Chamchad NNTP-Posting-Host: net.bio.net Dear Doctor: I am looking for Residency program in Pathology for PGY-1. If you have any information, please, let my know or forward my documents to person who is responsible for the program. Yours truly Dmitri Chamchad ___________________________________________________________________________ DMITRI CHAMCHAD, MD 715 Finch Ave. West, Apt.904 Phone: (416) 398-5947 Downsview, ON, M3H 4X7 CANADA e-mail: bk772@torfree.net **_______________________________________________________________** CAREER OBJECTIVE: To secure position within the American Residency Program. SKILLS & QUALIFICATIONS: - Physician - Pediatrician with 2 years experience. - Excellent communication and interpersonal skills. - Extensive experience in dealing with patients and all levels of hospital personnel. PROFESSIONAL EXPERIENCE: 1995-Present Central Registry for Nurses, Ontario, CCU Registered Nurse 1991-1993 "MEDINFORM" Co., Moscow, Russia, Histologist, Physician-Pediatrician (1992-1993) 1989-1992 Department of Histology and Embryology of Pediatric faculty at Moscow Medical University, Senior Lab. Technician. EDUCATION: 1995-1996 ECFMG Certification 0-520-647-9 USMLE Step I - 76 (182) passed 10.1995 USMLE Step II- 75 (172) passed 09.1996 English- Passed 1991-1992 Moscow Medical University, Moscow, USSR Internship - Pediatrics. 1985-1992 2nd Moscow Medical University. Physician-Pediatrician degree. 1980-1982 Moscow Medical College - RN diploma. PUBLICATIONS: 1. V.S.Sukhorukov, D.A.Chamchad "Definition of spermatogenetic layer maturity level in rats during regeneration or intact testicular development" 2. V.S.Sukhorukov, S.B.Tarabryn, D.A.Chamchad "Usage of Sertoli-cells-only syndrome as a model for investigation of some gonadal development regulation mechanisms "Actual Problems of Medical Embryology" 3. V.S.Sukhorukov, S.B.Tarabryn, I.A.Darenkov, A.A.Dreval, O.V.Volkova, A.K.Polonsky, D.A.Chamchad "The Method of male sterility treatment" Patent request N 48248664/14. 4. V.S.Sukhorukov, S.B.Tarabryn, D.A.Chamchad "Postnatal SCO-syndrome in rats as a model of paracrine regulation and regeneration research". 5. O.V.Volkova, S.B.Tarabryn, V.S.Sukhorukov, D.A.Chamchad "Paracrine regulation of male gonads. I. Interactions among somatic gonadal components." 6. O.V.Volkova, S.B.Tarabryn, V.S.Sukhorukov, D.A.Chamchad "Paracrine regulation of male gonads. II About the possibility of germ cell influence on somatic micro-environment" REFERENCES (available upon request): 1. Chief of Department of Histology and Embryology of Russian Medical University, Member of Medical Academy D.M. Prof. Olga V. Volkova Moscow, Ostrovitanova St. Building N1 ,Department of Histology and Embryology . Phone: (095)-434-4192 2. Scientific Chief M.D. Ph.D. Docent. Sergey B. Tarabryn Moscow, Ostrovitanova St. Building N1, Department of Histology and Embryology Phone: (095) 442-6323, (905)--434-5534 3. General Director "Medinform" Co. -- Victor I. Shustov Moscow, Bolotnikovskay St. 41-96 Phone: (095)--433-0520 North America: 1. Dr. Alexander Zonshayn, The Toronto Hospital, General Division, Phone: (416) 225-1946 2. Dr. Andrei Tchernov, Glace Bay Hospital, Nova Scotia Phone: (902) 849-5511 3. Dr. Svetlana Belyavskaya, Family Practice, Phone: (416) 630-1200 __________________________________________________________________________ PERSONAL STATEMENT DR. DMITRI CHAMCHAD A strong motivating power brought me up to this point of my career. I have always kept abreast of the latest developments in my professional field. I was a consistent and diligent student and performed well each year of my studies. After graduating from Medical School, I was working as a Physician for Medinform Company. I have always been interested in science. Even while a medical student, I worked as a Senior Lab. Technician at University Histology and Embryology Department. I gained great comprehension and knowledge of the deepest mechanisms of pathological processes at cellular and biochemical levels. Since I left Russia in 1993, I have lived in Canada. During this period I have broaden my views of Clinical medicine, have become fluent in English and prepared myself for American board examinations that I have recently passed. My work in Toronto's hospitals (as RN) helped me to become acquainted with North American rules, principles and laws in medicine. I am an efficient, dedicated, hardworking person and strongly motivated to advance in my career. I am comfortable working either alone or closely on a team. I have always been interested in art, literature and sports. I have excellent computer skills: I know Meditech, Windows95/NT, Microsoft Word, Excel and Internet tools. I hope that your program will expose me to a wide variety of cases and will give me a broad clinical base. It will also prepare me for a better understanding of patient's needs, will improve bedside communication skills, will teach me advanced diagnostic procedures, it will be an excellent introduction to American Clinical Practice. I wish to undergo a comprehensive and rigorous training in your residency program. I hope that the above information provided you with some insight into my background. Dmitri Chamchad M.D. 715 Finch ave. West apt.904 Downsview, Ontario, M3H 4X7 Canada. Phone:(416) 398-5947 e-mail: bk772@torfree.net From owner-ageing@net.bio.net Thu Apr 17 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!rill.news.pipex.net!pipex!netcom.net.uk!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!penguin.doc.ic.ac.uk!not-for-mail From: none@ic.ac.uk (Alex Hunter) Newsgroups: bionet.molbio.ageing,bionet.cellbiol Subject: Can exfoliant creams cause skin ageing? Date: Fri, 18 Apr 1997 22:38:26 GMT Organization: A poorly-installed InterNetNews site Lines: 13 Message-ID: <5j8u4e$s22$1@penguin.doc.ic.ac.uk> NNTP-Posting-Host: sysslip1.doc.ic.ac.uk X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.molbio.ageing:3316 bionet.cellbiol:7118 Hi, I was wondering if anyone could tell me whether skin creams which contain exfoliating complex can actually increase skin ageing rather than reducing it as the manufacturers claim? My reason for thinking this is that exfoliants remove the outer layer of skin and thus encourage cell division to replace this layer, and every time your cells divide errors can creep in to the DNA sequence, which, I'm told, is beleived to be the main cause of ageing. Thus you would expect increased ageing in the long term; while possibly reducing the appearance of ageing in the short term? Or have I got it completely wrong? PLEASE DO NOT POST EMAIL REPLIES AS MY ACCOUNT HAS NO EMAIL ADDRESS! From owner-ageing@net.bio.net Thu Apr 17 23:00:00 1997 Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news-peer.sprintlink.net!news.sprintlink.net!sprint!howland.erols.net!rill.news.pipex.net!pipex!netcom.net.uk!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!penguin.doc.ic.ac.uk!not-for-mail From: none@ic.ac.uk (Alex Hunter) Newsgroups: bionet.molbio.ageing Subject: Need advice on anti-ageing diet. Date: Fri, 18 Apr 1997 22:44:15 GMT Organization: A poorly-installed InterNetNews site Lines: 13 Message-ID: <5j8uff$s22$2@penguin.doc.ic.ac.uk> NNTP-Posting-Host: sysslip1.doc.ic.ac.uk X-Newsreader: Forte Free Agent 1.0.82 Hi, I was wondering if anyone could explain to me how I can switch to a restricted calorie diet of the type which has been found to reduce ageing and increase longevity in animal experiments for many years? I understand it involves reducing body weight to at least 10% below the normal minimum weight, and restricting your calorie intake in some way while replacing some essential nutrients with supplements. I do not know the details of which supplements to take and by how much the calorie intake must be reduced and how to monitor this accurately? Since I have repeatedly tried fairly low calorie diets from the age of around 20 (I am now 30), whilst remaining slightly over the average weight for my height for all this time: could this have already had any effect in delaying ageing? From owner-ageing@net.bio.net Fri Apr 18 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!mindspring!news.mindspring.com!usenet From: lockshin@mindspring.com (Richard A. Lockshin) Newsgroups: bionet.molbio.ageing Subject: Re: Molecular Processes of Ageing Date: Sat, 19 Apr 1997 14:04:55 GMT Organization: MindSpring Enterprises, Inc. Lines: 18 Message-ID: <5jajsi$lt3@camel3.mindspring.com> References: <33513550.38FC@cadvision.com> Reply-To: lockshin@mindspring.com NNTP-Posting-Host: ip71.garden-city3.ny.pub-ip.psi.net X-Server-Date: 19 Apr 1997 14:12:34 GMT X-Newsreader: Forte Free Agent 1.0.82 for cell death you might also be interested in http://www.celldeath-apoptosis.org Josh Christianson wrote: >Hi, > I am a grade 12 student from Beiseker, Alberta and my Bio teacher gave >me an assignment to go on the internet and find out as much as I can on >the molecular processes of Ageing, so if anyone here could help me out >by giving me info. on the subject or telling me what sites contain info. >on this subject, it would be much appreciated. > >Josh Christianson lockshin@stjohns.edu lockshin@mindspring.com check out Apoptosis/Programmed Cell Death Web Page http://rdz.stjohns.edu/~lockshin/index.html From owner-ageing@net.bio.net Sun Apr 20 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!newspump.sol.net!posts.execpc.com!earth.execpc.com!not-for-mail From: rreid@earth.execpc.com (Rodney Reid) Newsgroups: bionet.molbio.ageing Subject: Re: Need advice on anti-ageing diet. Date: 20 Apr 1997 21:55:04 -0500 Organization: Exec-PC Internet Lines: 29 Message-ID: <5jeku8$e5v$1@earth.execpc.com> References: <5j8uff$s22$2@penguin.doc.ic.ac.uk> NNTP-Posting-Host: earth.execpc.com X-Newsreader: TIN [version 1.2 PL2] Alex Hunter (none@ic.ac.uk) wrote: : Hi, I was wondering if anyone could explain to me how I can switch to : a restricted calorie diet of the type which has been found to reduce : ageing and increase longevity in animal experiments for many years? : I understand it involves reducing body weight to at least 10% below : the normal minimum weight, and restricting your calorie intake in some : way while replacing some essential nutrients with supplements. I do : not know the details of which supplements to take and by how much the : calorie intake must be reduced and how to monitor this accurately? : Since I have repeatedly tried fairly low calorie diets from the age : of around 20 (I am now 30), whilst remaining slightly over the average : weight for my height for all this time: could this have already had : any effect in delaying ageing? Its called the CRAN (Calorie Restricted Adequate(?) Nutrients) diet. "The 120-year diet" by Roy Walford (isbn 0-671-46677-1) has sample CRAN recipes. According to the old sci.l-e FAQ, slowly reducing your calorie intake over 4-6 years is the best way to do CRAN; so your low calorie diet experimentation may pay off by speeding up (for you) the time it takes for you to get there. If CRAN is done too rapidly, it reduces lifespan in animals. As far as the details on additional nutrients needed on a CRAN diet...hmmmm... Hasn't supplementation been a scientific holy war of sorts since the idea began? ...Rodney From owner-ageing@net.bio.net Sun Apr 20 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!news.bc.net!mongol.sasknet.sk.ca!news@mongol.sasknet.sk.ca From: Asha <"asha.(remove_to_reply)"@sk.sympatico.ca> Newsgroups: bionet.molbio.ageing,bionet.toxicology,bionet.biology.cardiovascular,sci.bio.technology Subject: Cardiovascular Disease Date: Mon, 21 Apr 1997 12:19:56 -0600 Organization: SaskNet News Distribution Lines: 15 Message-ID: <335BAFCC.7270@sk.sympatico.ca> NNTP-Posting-Host: halo25.sk.sympatico.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.02E-SYMPA (Win16; I) Xref: biosci bionet.molbio.ageing:3324 bionet.toxicology:1430 bionet.biology.cardiovascular:1638 sci.bio.technology:7813 I have a link you might be interested in that would be included in the category of "alternative medicine." It's a site that specializes in Coenzyme Q10, and has an extensive medical references section on Coenzyme Q10 and disease, including specialized information on heart disease. Although it is a commercial site, we hope that you find some useful information. http://www.nethomes.com/asha (homepage) URLs of interest: http://www.nethomes.com/asha/heart.htm http://www.nethomes.com/asha/ref2.htm (detailed references) Best Regards, From owner-ageing@net.bio.net Mon Apr 21 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!gondor!newshub.sdsu.edu!newshub.csu.net!news.ironhorse.com!mr.net!news.maxwell.syr.edu!news-peer.sprintlink.net!news.sprintlink.net!sprint!uunet!in2.uu.net!192.220.251.22!netnews.nwnet.net!news-hub.interserv.net!news.sprynet.com!not-for-mail From: jmhoward@sprynet.com (James Howard) Newsgroups: bionet.molbio.ageing Subject: DHEA, Alzheimer's Disease, and Depression Date: Wed, 23 Apr 1997 10:14:51 GMT Organization: Sprynet News Service Lines: 25 Message-ID: <335de0d3.3743208@news.sprynet.com> NNTP-Posting-Host: dd13-080.compuserve.com X-Newsreader: Forte Free Agent 1.1/32.230 In 1985, I predicted (copyrighted) that DHEA would be low in Alzheimer's disease and depression, and that it is the cause. The first report of low DHEA in AD was in 1989. I just found the following report that further supports my hypotheses. Wolkowitz OM, et al., "Dehydroepiandrosterone (DHEA) treatment of depression," Biol Psychiatry 41 (3): 311-318 (1997) "Dehydroepiandrosterone (DHEA) and its sulfate, DHEA-S, are plentiful adrenal steroid hormones that decrease with aging and may have significant neuropsychiatric effects. In this study, six middle-aged and elderly patients with major depression and low basal plasma DHEA and/or DHEA-S levels were openly administered DHEA (30-90 mg/d x 4 weeks) in doses sufficient to achieve circulating plasma levels observed in younger healthy individuals. Depression ratings, as well as aspects of memory performance significantly improved. One treatment-resistant patient received extended treatment with DHEA for 6 months: her depression ratings improved 48-72% and her semantic memory performance improved 63%. These measures returned to baseline after treatment ended. In both studies, improvements in depression ratings and memory performance were directly related to increases in plasma levels of DHEA and DHEA-S and to increases in their ratios with plasma cortisol levels. These preliminary data suggest DHEA may have antidepressant and promemory effects and should encourage double-blind trials in depressed patients." From owner-ageing@net.bio.net Mon Apr 21 23:00:00 1997 Path: biosci!daresbury!not-for-mail From: jcoward@mail.islandnet.com (Jim Coward) Newsgroups: bionet.molbio.ageing Subject: ITCH '98 CALL FOR PAPERS & POSTER CONTEST Date: 23 Apr 1997 00:27:21 +0100 Lines: 64 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <5jjhgp$hbn@mserv1.dl.ac.uk> X-Sender: jcoward@mail.islandnet.com Original-To: itch98-l@hsd.uvic.ca November 1-4, 1998 Victoria Conference Centre, Victoria BC Canada ITCH '98 CALL FOR PAPERS "NEW PARTNERSHIPS - BETTER CARE" is the working theme for the 1998 International Conference being held in Victoria, Canada, to discuss issues in information technology and community health. NEW PARTNESHIIPS are the result of the changing health system. This conference will look to these NEW PARTNERSHIPS and discuss how they are contributing to BETTER CARE. Particularly, ITCH '98 is interested in how information management and information systems are changing to improve community health and provide BETTER CARE. Given the diversity of ITCH conferences, the program will be organized so that papers are grouped according to professional and academic interest, wherever possible. Prospective contributors to the ITCH '98 Conference are encouraged to address topics related, but not limited, to the follow areas: APPLICATIONS Commmunity Health Information Systems Regional Information Systems Evaluation of Information Management Integrated Health Planning Medical Practices and Community Medicine Privacy and Confidentiliaty Health Policy TECHNOLOGY Intranet/Internet/WWW Telehealth/Telemedicine Expert Systems Technology Assessment Health Data Networks Security/Encryption Appropriate Technology The ITCH '98 Steering Committee invites interested persons to submit abstracts of up to 250 words by EMAIL or in Word 6, WP6 (or later versions) on diskette. The dealine for submission of abstracts for regular sessions or the Student Poster Contest is MARCH 1, 1998; authors will be notified by April 15, 1998 and completed papers are due by August 15, 1998. Please submit abstracts or requests for information to the address listed below. STUDENT POSTER CONTEST Students registered full-time in related undergraduate or graduate programs are invited to take part in a STUDENT POSTER CONTEST. Submissions should address topics related, but not limited, to those listed above. Student authors whose abstracts are accepted for poster presentation must also submit a full paper for inclusion in the proceedings. An independent panel will judge posters. The winner of the contest will receive a cash prize and a complimentary FULL registration to the conference. Additional prizes may be given. DEADLINE IS MARCH 1, 1998. CONTACT: Dr. Paul Fisher, Program Chair, ITCH '98 SchooL of Health Information Scince, PO Box 3050 University of Victoria, Victoria, BC, Canada V8W 3P5 Phone (250) 721-8576 Fax (250) 721-1457 Email his@hsd.uvic.ca Website: http://www.hsd.uvic.ca/HIS/ITCH/ITCH.htm From owner-ageing@net.bio.net Wed Apr 23 23:00:00 1997 Path: biosci!LAFN.ORG!ba182 From: ba182@LAFN.ORG (John Guerin) Newsgroups: bionet.molbio.ageing Subject: Research Available on Senescence in Long-Lived Fishes Date: 23 Apr 1997 20:31:04 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 55 Sender: daemon@net.bio.net Distribution: world Message-ID: <199704240331.AA25386@lafn.org> Reply-To: ba182@lafn.org NNTP-Posting-Host: net.bio.net You may recall previous postings I made inquiring about research studying senescence in long-lived fishes. In over a year and a half of literature search and talking to dozens of researchers, I have not found research addressing the longevity of fish such as sturgeon, flatfish, rockfish and probably carp. One difficulty of course is getting a supply of hundred year old fish! Recently, through working with the state of Alaska, I have come across rockfish population samples that look very promising. I have charts that show Frequency/Age distribution, and Length/Age distribution. I will have them available soon as an e-mail attachment. Of particular interest is the upper ages of this rockfish species, as summarized in the following table. The 573 total rockfish were randomly sampled between 1994 - 1996, from commercial fish landings: Age Group Freq % 50-59 28 4.9% 60-69 29 5.1% 70-79 11 1.9% 80-89 10 1.7% 90-99 10 1.7% 100-107 4 0.7% TOTAL 92 16.0% By selecting larger and "scruffier" looking rockfish, the proportion of older fish in a sample could be increased significantly, ensuring a sufficient sample size. These fish are not endangered, and in fact research on older fish might raise awareness about their diminishing numbers. A sample of these centenarian fish would allow comparison to younger fish, to gradually senescent fish, and to other species. Some potential areas of research include reproductive and organ pathology, cellular tests such as oxidative damage, and DNA analysis and comparison. I can provides samples of these older rockfish to researcher(s) interested in testing the above areas. Funding is dependent on the specific research plan developed. If you are interested in this research, know of other researchers who would be, or would like a copy of my abstract or additional information, please send me an e-mail. I will post additional information as appropriate. Sincerely, John C. Guerin ba182@lafn.org -- From owner-ageing@net.bio.net Wed Apr 23 23:00:00 1997 Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!newsxfer3.itd.umich.edu!newsxfer.itd.umich.edu!news.mtu.edu!msunews!netnews.upenn.edu!brass6.med.upenn.edu!user From: obrien@pharm.med.upenn.edu (:-Peter) Newsgroups: bionet.cellbiol,bionet.molbio.ageing Subject: Re: Need advice on anti-ageing diet. Date: 24 Apr 1997 18:32:53 GMT Organization: U. of Pennsylvania Lines: 54 Message-ID: References: <5j8unm$s22$3@penguin.doc.ic.ac.uk> <335CB9C8.5BC1@mailer.meb.uni-bonn.de> NNTP-Posting-Host: brass6.med.upenn.edu Xref: biosci bionet.cellbiol:7154 bionet.molbio.ageing:3330 >rreid@earth.execpc.com (Rodney Reid) opined: >>Alex Hunter (none@ic.ac.uk) wrote: >>: Hi, I was wondering if anyone could explain to me how I can switch to >>: a restricted calorie diet of the type which has been found to reduce >>: ageing and increase longevity in animal experiments for many years? >>: I understand it involves reducing body weight to at least 10% below >>: the normal minimum weight, and restricting your calorie intake in some >>: way while replacing some essential nutrients with supplements. I do >>: not know the details of which supplements to take and by how much the >>: calorie intake must be reduced and how to monitor this accurately? >>: Since I have repeatedly tried fairly low calorie diets from the age >>: of around 20 (I am now 30), whilst remaining slightly over the average >>: weight for my height for all this time: could this have already had >>: any effect in delaying ageing? >Its called the CRAN (Calorie Restricted Adequate(?) Nutrients) >diet. "The 120-year diet" by Roy Walford (isbn 0-671-46677-1) has sample >CRAN recipes. According to the old sci.l-e FAQ, slowly reducing your >calorie intake over 4-6 years is the best way to do CRAN; so your low >calorie diet experimentation may pay off by speeding up (for you) the time >it takes for you to get there. If CRAN is done too rapidly, it reduces >lifespan in animals. Let's not forget the updated version called CRANK. It's fairly complex, but I'll summarize and simplify it for the lay public: 1. Take one Fiesta, Sprint, Mini, or other teeny-tiny auto, modify it to attain light speed. 2.CRANK IT UP. 3. Fly it to the nearest Black Hole, remain on the outer edge only, since entry will cause drastic reduction in body fat volume, which may be unhealthy. 4. Eat as much as you want of whatever you want, for as long as you want. 5. Return to Earth (leave the car hidden, it will be embarrassingly outdated). You will appear to be younger than your chronological age, and will have lost a seemingly infinite amount of weight compared to your in-flight mass, regardless of your diet! I guarantee that if you follow this diet, the results will astound you! :-Peter From owner-ageing@net.bio.net Wed Apr 23 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!cs.utexas.edu!news.tamu.edu!news From: Dawn Newsgroups: bionet.cellbiol,bionet.molbio.ageing Subject: Re: Need advice on anti-ageing diet. Date: Thu, 24 Apr 1997 17:45:14 -0500 Organization: Texas A&M Univ., College of Medicine, Dept of Medical Biochemistry and Genetics Lines: 64 Message-ID: <335FE27A.1B3C@bigfoot.com> References: <5j8unm$s22$3@penguin.doc.ic.ac.uk> <335CB9C8.5BC1@mailer.meb.uni-bonn.de> Reply-To: DawnC@bigfoot.com NNTP-Posting-Host: modem-0368.rns.tamu.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit NNTP-Posting-Date: 24 Apr 1997 22:43:31 GMT X-Mailer: Mozilla 3.0 (Win95; I) To: :-Peter Xref: biosci bionet.cellbiol:7155 bionet.molbio.ageing:3331 :-Peter wrote: :Alex Hunter (none@ic.ac.uk) wrote: : Hi, I was wondering if anyone could explain to me how I can switch to : a restricted calorie diet of the type which has been found to reduce : ageing and increase longevity in animal experiments for many years? > >Its called the CRAN (Calorie Restricted Adequate(?) Nutrients) > >diet. "The 120-year diet" by Roy Walford (isbn 0-671-46677-1) has sample > >CRAN recipes. According to the old sci.l-e FAQ, slowly reducing your > >calorie intake over 4-6 years is the best way to do CRAN; so your low > >calorie diet experimentation may pay off by speeding up (for you) the time > >it takes for you to get there. If CRAN is done too rapidly, it reduces > >lifespan in animals. > > Let's not forget the updated version called CRANK. It's fairly complex, > but I'll summarize and simplify it for the lay public: > > 1. Take one Fiesta, Sprint, Mini, or other teeny-tiny auto, modify it to > attain light speed. Ah, but it still has mass, and therefore, shall never attain light speed... unless you do a "little trick".... > 2.CRANK IT UP. Unleaded? > 3. Fly it to the nearest Black Hole, remain on the outer edge only, > since entry will cause drastic reduction in body fat volume, which may be > unhealthy. Shouldn't that be Hole of Color? (something tells me that someone somewhere is going to flame me for this remark) > 4. Eat as much as you want of whatever you want, for as long as you want. Ah, but who delivers in space? > 5. Return to Earth (leave the car hidden, it will be embarrassingly outdated). But will Earth still exist? And, if it does, where will it be by then? > You will appear to be younger than your chronological age, and will have > lost a seemingly infinite amount of weight compared to your in-flight > mass, regardless of your diet! So I should bring smaller jeans with me in preparation...? > I guarantee that if you follow this diet, the results will astound you! And what do you back this guarantee up with? > :-Peter -- -Dawn- Time is the best teacher. Unfortunately, it kills all of its students. The Chako Rescue Association for the American Pit Bull Terrier http://members.tripod.com/~DawnC From owner-ageing@net.bio.net Thu Apr 24 23:00:00 1997 Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!europa.clark.net!newsfeed2!howland.erols.net!newspump.sol.net!posts.execpc.com!earth.execpc.com!not-for-mail From: rreid@earth.execpc.com (Rodney Reid) Newsgroups: bionet.cellbiol,bionet.molbio.ageing Subject: Re: Need advice on anti-ageing diet. Followup-To: bionet.cellbiol,bionet.molbio.ageing Date: 25 Apr 1997 01:43:13 -0500 Organization: Exec-PC Internet Lines: 30 Message-ID: <5jpjq1$ifa$1@earth.execpc.com> References: <5j8unm$s22$3@penguin.doc.ic.ac.uk> <335CB9C8.5BC1@mailer.meb.uni-bonn.de> NNTP-Posting-Host: earth.execpc.com X-Newsreader: TIN [version 1.2 PL2] Xref: biosci bionet.cellbiol:7159 bionet.molbio.ageing:3332 : Let's not forget the updated version called CRANK. It's fairly complex, : but I'll summarize and simplify it for the lay public: : 1. Take one Fiesta, Sprint, Mini, or other teeny-tiny auto, modify it to : attain light speed. : 2.CRANK IT UP. : 3. Fly it to the nearest Black Hole, remain on the outer edge only, : since entry will cause drastic reduction in body fat volume, which may be : unhealthy. : 4. Eat as much as you want of whatever you want, for as long as you want. : 5. Return to Earth (leave the car hidden, it will be embarrassingly outdated). : You will appear to be younger than your chronological age, and will have : lost a seemingly infinite amount of weight compared to your in-flight : mass, regardless of your diet! : I guarantee that if you follow this diet, the results will astound you! : :-Peter No no no! That's the Crank (methamphetamine) diet: Lose all the weight, and never miss any of your favorite game shows, infomercials, sleep, etc. Of course you won't look quite so young :) ...Rodney From owner-ageing@net.bio.net Sun Apr 27 23:00:00 1997 Newsgroups: bionet.molbio.ageing Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ais.net!ix.netcom.com!luly From: luly@netcom.com (Robert Luly) Subject: Re: Research Available on Senescence in Long-Lived Fishes Message-ID: Sender: luly@netcom13.netcom.com Reply-To: luly@netcom.com Organization: Netcom On-Line Services X-Newsreader: Forte Free Agent 1.0.82 References: <199704240331.AA25386@lafn.org> Date: Mon, 28 Apr 1997 17:09:43 GMT Lines: 64 ba182@LAFN.ORG (John Guerin) wrote: Hello John; You may already know this but according to Leonard Haylfick in his ('96) book, "How and Why We Age", Most animals that don't have a limit to their adult size *DON'T AGE* ! (But, they are not Imortal). Regards R. Luly >You may recall previous postings I made inquiring about research studying >senescence in long-lived fishes. In over a year and a half of literature >search and talking to dozens of researchers, I have not found research >addressing the longevity of fish such as sturgeon, flatfish, rockfish and >probably carp. One difficulty of course is getting a supply of hundred >year old fish! >Recently, through working with the state of Alaska, I have come across >rockfish population samples that look very promising. I have charts >that show Frequency/Age distribution, and Length/Age distribution. I >will have them available soon as an e-mail attachment. >Of particular interest is the upper ages of this rockfish species, as >summarized in the following table. The 573 total rockfish were randomly >sampled between 1994 - 1996, from commercial fish landings: > Age Group Freq % > 50-59 28 4.9% > 60-69 29 5.1% > 70-79 11 1.9% > 80-89 10 1.7% > 90-99 10 1.7% > 100-107 4 0.7% > TOTAL 92 16.0% >By selecting larger and "scruffier" looking rockfish, the proportion of >older fish in a sample could be increased significantly, ensuring a >sufficient sample size. These fish are not endangered, and in fact >research on older fish might raise awareness about their diminishing >numbers. >A sample of these centenarian fish would allow comparison to younger >fish, to gradually senescent fish, and to other species. Some potential >areas of research include reproductive and organ pathology, cellular >tests such as oxidative damage, and DNA analysis and comparison. >I can provides samples of these older rockfish to researcher(s) >interested in testing the above areas. Funding is dependent on the >specific research plan developed. >If you are interested in this research, know of other researchers who >would be, or would like a copy of my abstract or additional information, >please send me an e-mail. I will post additional information as >appropriate. >Sincerely, John C. Guerin > ba182@lafn.org >-- From owner-ageing@net.bio.net Sun Apr 27 23:00:00 1997 Path: biosci!UIOWA.EDU!john-menninger From: john-menninger@UIOWA.EDU ("John R. Menninger") Newsgroups: bionet.molbio.ageing Subject: Senescence in fish Date: 28 Apr 1997 12:45:32 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 20 Sender: daemon@net.bio.net Distribution: world Message-ID: <199704281945.MAA01806@net.bio.net> NNTP-Posting-Host: net.bio.net ba182@LAFN.ORG (John Guerin) wrote: >...You may recall previous postings I made inquiring about research studying >senescence in long-lived fishes. In over a year and a half of literature >search and talking to dozens of researchers, I have not found research >addressing the longevity of fish such as sturgeon, flatfish, rockfish and >probably carp. ... For a review of the older literature (and a general look at the problem from a surprising source!) see Comfort, A. (1956, 1974) Ageing: The Biology of Senescence, Elsevier North Holland, Inc. (New York), p. 89 ff. -- Good luck, John Menninger John R. Menninger john-menninger@uiowa.edu