From owner-ageing@net.bio.net Fri May 02 23:00:00 1997 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.molbio.ageing Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 3 May 1997 02:00:10 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 239 Sender: daemon@net.bio.net Distribution: world Message-ID: <199705030900.CAA26238@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net From owner-ageing@net.bio.net Sun May 04 23:00:00 1997 Path: biosci!gerisource.com!info From: info@gerisource.com (Gerisource) Newsgroups: bionet.molbio.ageing Subject: Free sample/clinical newsletter Date: 4 May 1997 23:19:54 -0700 Organization: GERISOURCE Lines: 5 Sender: daemon@net.bio.net Distribution: world Message-ID: <336C924A.7E69@gerisource.com> Reply-To: info@gerisource.com NNTP-Posting-Host: net.bio.net GERISOURCE, the clinical newsletter for long term care, is now online at http://www.gerisource.com, featuring a sample issue on fall prevention, clinical tips, Resource of the Month,clinical abstracts updated monthly, and e-mail link for "free trial issue". Contact person: Kristine Abney, RN, MN, Editor, info@gerisource.com. From owner-ageing@net.bio.net Sun May 04 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news.mindspring.com!usenet From: lockshin@mindspring.com (Richard A. Lockshin) Newsgroups: bionet.molbio.ageing Subject: NYC Cell Death Soc No May Meeting Date: Mon, 05 May 1997 19:51:41 GMT Organization: MindSpring Enterprises, Inc. Lines: 10 Message-ID: <5kle4r$5jt@camel1.mindspring.com> Reply-To: lockshin@mindspring.com NNTP-Posting-Host: ip75.an18-new-york4.ny.pub-ip.psi.net X-Server-Date: 5 May 1997 19:58:19 GMT X-Newsreader: Forte Free Agent 1.0.82 Another meeting at Rockefeller forced a schedule change, and one of our speakers was unable to reschedule. We have therefore cancelled the May meeting. A June meeting will be announced shortly. Richard A. Lockshin (lockshin@mindspring.com;lockshin@sjumusic.stjohns.edu) check out Cell Death Soc web page: http://rdz.stjohns.edu/~lockshin/index.html From owner-ageing@net.bio.net Mon May 05 23:00:00 1997 Newsgroups: bionet.molbio.ageing Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news-peer.sprintlink.net!Sprint!news-east.sprintlink.net!news-dc-26.sprintlink.net!news.sprintlink.net!news-dc-9.sprintlink.net!NEWS!not-for-mail From: "Joseph Cannon" Subject: DHEA and CV problems in postmenapausal women? Message-ID: <01bc59b1$44f631c0$741b29cf@JCannon> Date: Tue, 06 May 1997 00:07:49 GMT X-Newsreader: Microsoft Internet News 4.70.1161 Lines: 10 Im just completed a paper on DHEA and discovered that it may increase death from CV diesase in postmenapausal women. while the studies were epidemeological and older ( from the mid 80's) I was wondering what the consensus was on this at this point? please email me. thanks -- Joseph Patrick Cannon BS chemistry and Biology MS Exercise Physiology (May 1997) CSCS From owner-ageing@net.bio.net Sun May 11 23:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.maxwell.syr.edu!news.bc.net!mongol.sasknet.sk.ca!news@mongol.sasknet.sk.ca From: Asha Newsgroups: bionet.molbio.ageing,bionet.toxicology,bionet.biology.cardiovascular,sci.bio.technology Subject: Cardiovascular Disease Date: Mon, 12 May 1997 02:49:09 -0600 Organization: SaskNet News Distribution Lines: 15 Message-ID: <3376D985.2060@remove.sk.sympatico.ca> NNTP-Posting-Host: vultee47.sk.sympatico.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.02E-SYMPA (Win16; I) Xref: biosci bionet.molbio.ageing:3351 bionet.toxicology:1495 bionet.biology.cardiovascular:1691 sci.bio.technology:7970 I have a link you might be interested in that would be included in the category of "alternative medicine." It's a site that specializes in Coenzyme Q10, and has an extensive medical references section on Coenzyme Q10 and disease, including specialized information on heart disease. Although it is a commercial site, we hope that you find some useful information. http://www.nethomes.com/asha (homepage) URLs of interest: http://www.nethomes.com/asha/heart.htm http://www.nethomes.com/asha/ref2.htm (detailed references) Best Regards, From owner-ageing@net.bio.net Sun May 11 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!swrinde!howland.erols.net!ix.netcom.com!netcom.net.uk!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!gmorley From: gmorley@hgmp.mrc.ac.uk (Mr. G. Morley) Newsgroups: bionet.molbio.ageing Subject: Postdoc position available Date: 12 May 1997 14:46:04 GMT Organization: MRC Human Genome Resource Centre Lines: 9 Message-ID: <5l7afc$4ja@mercury.hgmp.mrc.ac.uk> NNTP-Posting-Host: tin.hgmp.mrc.ac.uk A molecular biologist postdoc position is available to work in the institute of Obstretrics and Gynaecology at the Hammersmith hospital, London, England. For more details please check out: http://www.caduceus.demon.co.uk/postdoc.html or e-mail Dr.Nick Dibb at: ndibb@rpms.ac.uk From owner-ageing@net.bio.net Thu May 15 23:00:00 1997 Path: biosci!TENET.EDU!dashley From: dashley@TENET.EDU (Don Ashley) Newsgroups: bionet.molbio.ageing Subject: Re: Anti-ageing effects of kinetin Date: 16 May 1997 06:56:56 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 18 Sender: daemon@net.bio.net Distribution: world Message-ID: References: <5lh6sq$g7o@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net On 16 May 1997, Suresh Rattan wrote: > For the last several years I have been reporting here the progress as > regards the anti-ageing effects of the plant growth hormone kinetin. Just > to remind you, we have previously published the youth-promoting and > anti-ageing effects of kinetin on human cells; life prolongation of > Drosophila; and the identification of kinetin in natural sources, mainly in > DNA. Now, we have published another paper showing that kinetin increases > longevity of fruitflies by increasing some of the antioxidant enzyme > systems. However, this increased lifespan is achieved at a cost of reduced > egg laying. Might this mean that increased longevity comes at the cost of decreased sexual performance also? From owner-ageing@net.bio.net Thu May 15 23:00:00 1997 Path: biosci!daresbury!not-for-mail From: rattan@imsb.au.dk (Suresh Rattan) Newsgroups: bionet.molbio.ageing Subject: Anti-ageing effects of kinetin Date: 16 May 1997 09:46:18 +0100 Lines: 49 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <5lh6sq$g7o@mserv1.dl.ac.uk> Original-To: ageing@dl.ac.uk For the last several years I have been reporting here the progress as regards the anti-ageing effects of the plant growth hormone kinetin. Just to remind you, we have previously published the youth-promoting and anti-ageing effects of kinetin on human cells; life prolongation of Drosophila; and the identification of kinetin in natural sources, mainly in DNA. Now, we have published another paper showing that kinetin increases longevity of fruitflies by increasing some of the antioxidant enzyme systems. However, this increased lifespan is achieved at a cost of reduced egg laying. The complete reference to the published paper is as below (along with its abstract) In: Biochemistry and Molecular Biology International, vol 41; pp. 869-875, 1997 (April issue) Increased longevity of kinetin-fed zaprionus fruitflies is accompanied by their reduced fecundity and enhanced catalase activity Suraj P. Sharma1, Jaspal Kaur1 and Suresh I. S. Rattan2* 1 Department of Zoology, Guru Nanak Dev University, Amritsar - 143005, India 2 Laboratory of Cellular Ageing, Department of Molecular and Structural Biology, Aarhus University, DK-8000 Aarhus - C, Denmark Summary: Kinetin, a cytokinin plant growth hormone, retards senescence in plants, delays aging in human cells in culture, slows down development of insects and prolongs their lifespan. We have now observed that the increased longevity of Kn-fed Zaprionus fruitflies was accompanied by an increase in the specific activity of catalase during developmental stages and in adult insects. In addition, the egg laying capacity of Kn-fed fruitflies was reduced drastically as compared with those kept on a normal diet. These results support the view that improved maintenance of the soma and prolongation of its life is achieved at the cost of decreased reproductive activity. Good reading, Dr. Suresh I.S. Rattan, PhD; DSc Laboratory of Cellular Ageing Department of Chemistry Aarhus University DK-8000 Aarhus - C Denmark (Phone: +45 8942 3956; Fax: +45 8619 6199) From owner-ageing@net.bio.net Thu May 15 23:00:00 1997 Newsgroups: bionet.molbio.ageing Path: biosci!bcm.tmc.edu!cs.utexas.edu!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news-peer.sprintlink.net!news-pull.sprintlink.net!Sprint!news.sprintlink.net!news-fw-22.sprintlink.net!news.gdbnet.ad.jp!news From: ALAIN Subject: QQQQQ Content-Type: text/plain; charset=us-ascii Message-ID: <337872EF.51FC@POBOXES.COM> Sender: news@ns.gdbnet.ad.jp Nntp-Posting-Host: laus3-p01.vtx.ch Reply-To: AC@POBOXES.COM Content-Transfer-Encoding: 7bit Organization: Genome Database Network in Japan Mime-Version: 1.0 Date: Tue, 13 May 1997 13:55:59 GMT X-Mailer: Mozilla 3.0 (Win95; I) Lines: 1 TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT From owner-ageing@net.bio.net Thu May 15 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!gondor!newshub.sdsu.edu!news.sgi.com!howland.erols.net!ais.net!newsfeed.direct.ca!news.bctel.net!not-for-mail From: Ron Neumeyer Newsgroups: bionet.molbio.ageing Subject: Zeiss Inverted Microscope Date: Fri, 16 May 1997 07:33:48 -0700 Organization: BCTEL Advanced Communications Lines: 27 Message-ID: <337C704C.1C6D@bc.sympatico.ca> Reply-To: micron@bc.sympatico.ca NNTP-Posting-Host: vanc01m02-71.bctel.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01C-SYMPA (Win95; U) I have a Zeiss (West German) "Standard", inverted microscope that is surplus to my needs, which features: - phase 1, 2 and bright field long working distance condensers; - Zeiss 10x and 25x (Neofluar) phase objectives; - Leitz 12x apochromatic brightfield objective with DIN adaptor; - 10x wide field eyepieces; - binocular head; - 45 degree monohead (for use with a still or video camera) - large mechanical stage with drop controls; - aluminum slide and cell carrier; - 60watt/12volt illuminator with internal rheostat controlled transformer; - numerous accessories in wood drawer unit that can serve as a raised base; - new condition, very high quality and easy to use; - asking $1000; Please call Ron at (604) 582-2552, or send an e-mail to arrange for a demonstration (can send a JPEG image). *************************************** Ron Neumeyer, 11135 Kendale Way, North Delta, BC V4C 3P7 CANADA (604-582-2552) *************************************** From owner-ageing@net.bio.net Fri May 16 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!newsfeeds.sol.net!newspump.sol.net!posts.execpc.com!earth.execpc.com!not-for-mail From: rreid@earth.execpc.com (Rodney Reid) Newsgroups: bionet.molbio.ageing,sci.life-extension Subject: Re: Anti-ageing effects of kinetin Date: 16 May 1997 23:21:20 -0500 Organization: More crazy talk! Lines: 63 Distribution: world Message-ID: <5ljbo0$p3g$1@earth.execpc.com> References: <5lh6sq$g7o@mserv1.dl.ac.uk> NNTP-Posting-Host: earth.execpc.com X-Newsreader: TIN [version 1.2 PL2] Xref: biosci bionet.molbio.ageing:3362 sci.life-extension:17505 Don, (I crossposted this to sci.life-extension also) Maybe it means that they're just less fertile, or (my hypothesis) that the anti-aging effects of kinetin are really part of a larger scheme of things that goes like this: Spring comes to town. Plants everywhere, being in their growing season, produce kinetin in adundance. Animals everywhere, being hungry, eat the growing kinetin-rich plants. Ooops!!! Guess maximum reproduction year round isn't in the cards for them. The kinetin keeps them around longer (relative to the other seasons) although.... The annual growing cycle continues on, and Summer and Fall come. Kinetin production in plants decreases, animals everywhere eating the now kinetin (free? lessened?) plants experience a surge in fertility - Mating season comes along. Winter comes (burrrrrr!!!) and everything dies, moves, or goes into hibernation. Of course, every living thing is waiting for the next spring, when many of them have babies and the whole cycle starts all over again. Of course this hypothesis rests on kinetin really being a seasonal plant hormone (or mostly seasonal for the bulk of plant matter eaten - I guess a young tree might produce more % kinetin than a mature tree in the same growing season) AND that most animals are affected by the reproductive dampening effects of kinetin. Which brings me to a another question/test: Carnivores and Omnivores should have a more varied mating/birthing season than pure herbivores, being that they would be less dependant on kinetin regulating things.... I dunno if they do or not though. Here is a pointer to NCBI's pubmed: http://www.ncbi.nlm.nih.gov/Entrez ...go to the basic search and enter "kinetin & human & plant" for a couple abstracts about it (some by the originator of this thread). A search at http://www.dejanews.com for "kinetin" in their old databse pulled up a few articles too. ...Rodney Don Ashley (dashley@TENET.EDU) wrote: : On 16 May 1997, Suresh Rattan wrote: : > For the last several years I have been reporting here the progress as : > regards the anti-ageing effects of the plant growth hormone kinetin. Just : > to remind you, we have previously published the youth-promoting and : > anti-ageing effects of kinetin on human cells; life prolongation of : > Drosophila; and the identification of kinetin in natural sources, mainly in : > DNA. Now, we have published another paper showing that kinetin increases : > longevity of fruitflies by increasing some of the antioxidant enzyme : > systems. However, this increased lifespan is achieved at a cost of reduced : > egg laying. : Might this mean that increased longevity comes at the cost of decreased : sexual performance also? From owner-ageing@net.bio.net Sat May 17 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!swrinde!cs.utexas.edu!news-peer.sprintlink.net!news-pull.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.direct.ca!nntp.portal.ca!news.bc.net!mongol.sasknet.sk.ca!news@mongol.sasknet.sk.ca From: Asha Newsgroups: bionet.molbio.ageing,bionet.toxicology,bionet.biology.cardiovascular,sci.bio.technology Subject: CoQ10 Date: Sat, 17 May 1997 22:08:43 -0600 Organization: SaskNet News Distribution Lines: 14 Message-ID: <337E80CB.4F86@sk.sympatico.ca> Reply-To: asha_@sk.sympatico.ca NNTP-Posting-Host: breda48.sk.sympatico.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01 (Win16; I) Xref: biosci bionet.molbio.ageing:3364 bionet.toxicology:1515 bionet.biology.cardiovascular:1708 sci.bio.technology:7984 I have a link you might be interested in that would be included in the category of "alternative medicine." It's a site that specializes in Coenzyme Q10, and has an extensive medical references section on Coenzyme Q10 and disease, including specialized information on heart disease. http://www.nethomes.com/asha (homepage) URLs of interest: http://www.nethomes.com/asha/heart.htm http://www.nethomes.com/asha/ref2.htm (detailed references) Best Regards, From owner-ageing@net.bio.net Sun May 18 23:00:00 1997 Path: biosci!bcm.tmc.edu!cs.utexas.edu!news.maxwell.syr.edu!news.nacamar.de!news.apfel.de!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!newsfeed.internetmci.com!in2.uu.net!151.99.250.2!server-b.cs.interbusiness.it!usenet From: "Datalab" Newsgroups: bionet.molbio.ageing Subject: URGENT HELP!!! Date: 19 May 1997 17:40:47 GMT Organization: DATALAB Lines: 21 Message-ID: <01bc647b$95696a80$436cf3c2@DKT.DATALAB.IT> NNTP-Posting-Host: 194.243.108.67 X-Newsreader: Microsoft Internet News 4.70.1161 We need help for a 6 years old italian girl. She's dying at the Brotzu Hospital of Cagliari - Italy. Doc.Pettinao She has a syndrome characterized from: - Hypercoagulation of the blood - Formation of red thrombus with white core every 15 sec. 2-3 cm. longs Till now it has not been possible to make a diagnosis. If someone has some information that can help to make a diagnosis please get in contact with: lukrezia@mbox.vol.it stefania@alanet.it schintu@pan.bio.uniroma1.it psico@mbox.vol.it Please forward this message to everyone. THANK YOU From owner-ageing@net.bio.net Mon May 19 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!mindspring!usenet From: lockshin@mindspring.com (Richard A. Lockshin) Newsgroups: bionet.molbio.ageing Subject: NYC Cell Death June 4 meeting Date: Tue, 20 May 1997 18:57:29 GMT Organization: MindSpring Enterprises, Inc. Lines: 30 Message-ID: <5lssji$tqs@camel2.mindspring.com> Reply-To: lockshin@mindspring.com NNTP-Posting-Host: ip142.an23-new-york4.ny.pub-ip.psi.net X-Server-Date: 20 May 1997 19:04:18 GMT X-Newsreader: Forte Free Agent 1.0.82 Next meeting Cell Death Society Meeting Wednesday, June 4, 1997 6:00-6:30 PM Pizza, 6:30-8:00 PM Talks and Discussion Rockefeller University, 130 York Ave. Weiss Research Bldg., Room 301 Free parking after 5 PM at 66th St. and York Ave. Please car pool as parking space is limited. Speakers: 1. Graciana Diez Roux, Skirball Institute of NYU Medical Center, Dept. of Cell Biology Macrophage-induced apoptosis of normal endothelial cells in vivo. 2. Nicos Karasavvas, Queens College of CUNY and Memorial Sloan Kettering Cancer Center Relationship of ceramide to cell death Important notes: To help plan for pizza and number of attendees, please call Dr. Zakeri's lab (718-997-3429) to indicate that you are coming. If you want to receive information about the Cell Death Society, please contact Dr. Zakeri's lab to verify your phone, fax, and email listings. If you have a new email address and did not receive this message by email, please reply to this message or register on our society page.+ Richard A. Lockshin (lockshin@mindspring.com;lockshin@sjumusic.stjohns.edu) check out Cell Death Soc web page: http://rdz.stjohns.edu/~lockshin/index.html From owner-ageing@net.bio.net Tue May 20 23:00:00 1997 Path: biosci!bcm.tmc.edu!cs.utexas.edu!news-peer.sprintlink.net!news.sprintlink.net!Sprint!howland.erols.net!newsfeed.internetmci.com!in3.uu.net!152.163.170.17!newstf01.news.aol.com!audrey02.news.aol.com!not-for-mail From: janczek@aol.com (JanCzek) Newsgroups: bionet.molbio.ageing Subject: Enclosed animal exerciser with VO2/VCO2 measurements Date: 21 May 1997 09:26:54 GMT Lines: 7 Message-ID: <19970521132600.JAA09921@ladder02.news.aol.com> NNTP-Posting-Host: ladder02.news.aol.com X-Admin: news@aol.com Organization: AOL http://www.aol.com We developed modular enclosed treadmill for exercising rats (or mice) with simultaneous measurements of oxygen consumption and CO2 production. I can send description and references to interested parties. Please provide street address. Jan Czekajewski, Ph.D. Janczek@aol.com From owner-ageing@net.bio.net Wed May 21 23:00:00 1997 Path: biosci!internet!biosci!not-for-mail From: kristoff (David Kristofferson) Newsgroups: bionet.molbio.ageing Subject: IMPORTANT - BIOSCI moving to Stanford! Date: 21 May 1997 20:43:01 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 55 Sender: daemon@net.bio.net Distribution: world Message-ID: <199705220342.UAA01912@net.bio.net> NNTP-Posting-Host: net.bio.net After more than a decade of serving the biology community on the BIOSCI project, I have decided that it is time for me to pass the torch. The demands of my career and family are making it increasingly difficult for me to run BIOSCI adequately on a part-time basis, and I've decided that I would do the project more harm than good by clinging to it. Therefore I have concluded an agreement with the Stanford University Libraries to take over the management of the BIOSCI project effective 6 June 1997. Many of you know the work of the Stanford Libraries through HighWire Press which has done an excellent job bringing the Journal of Biological Chemistry, Science Magazine, and other prestigious journals to the WWW (see http://highwire.stanford.edu/). I have every confidence that Stanford will provide an environment where the BIOSCI project can flourish. The BIOSCI team at Daresbury will continue to support the project in Europe, and Dave Mack and Julie Lawrence on the current BIOSCI staff will continue to assist the new team at Stanford. The project will be managed by Serge Taylor of the Stanford Libraries who is responsible for developing Web-based "knowledge environments" for scientists. I will still participate with the project in an advisory capacity but have to phase myself out of day-to-day operations. Many of you who read bionet.announce, bionet.biology.computational, and bionet.jobs.offered (the groups that I moderate) have been aware of the recent posting delays that my busy schedule has inflicted on those newsgroups. I am pleased to announce that Todd McGee, Scientific Advisor of the HighWire Press, will be taking over moderation of those groups from me this week. ** NOTE ** - The BIOSCI hardware will be down for backups on 6 June and will be moved over the weekend of June 7 and 8. We will be changing the IP number of the machine, but the host name and all mailing addresses will remain unchanged. There may be a few days of service disruption during this time due to the move unfortunately, just as we experienced in BIOSCI's previous move. We hope to keep this to a minimum. We will post status reports on the move to bionet.announce before and after it happens. Please watch that newsgroup for details. It has been a pleasure serving all of you since the "early days" of biology on the Internet. I've had the pleasure of not only "knowing" many of you over the Internet, but have also met literally thousands of biologists around the U.S. and elsewhere during the many Internet training seminars that I gave over the last decade. I've been truly fortunate to have been given the chance to play a role in the growth of biology on the Internet. This is something I will always treasure. Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net From owner-ageing@net.bio.net Wed May 21 23:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!newsfeed.internetmci.com!rill.news.pipex.net!pipex!tank.news.pipex.net!pipex!usenet From: hk05@dial.pipex.com Newsgroups: bionet.molbio.ageing Subject: CR MAILING LIST? Date: Thu, 22 May 1997 07:52:31 GMT Organization: UUNet PIPEX server (post doesn't reflect views of UUNet PIPEX) Lines: 15 Message-ID: <3383a5ee.2569797@news.dial.pipex.com> NNTP-Posting-Host: ao108.du.pipex.com X-Newsreader: Forte Free Agent 1.1/16.230 Hi, I wonder if anyone here can help me? I'm looking to subscribe to a Calorie Restriction for Life Extension Mailing List. Does anyone here know of any and how to subscribe to it. I'm currently pursuing CR and need a connection to a regular, reliable source of info - and support. Thanks In Advance! Iain Whitehead. From owner-ageing@net.bio.net Thu May 22 23:00:00 1997 Path: biosci!daresbury!uninett.no!Norway.EU.net!EU.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!europa.clark.net!disgorge.news.demon.net!demon!dispatch.news.demon.net!demon!baron.netcom.net.uk!netcom.net.uk!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!lyra.csx.cam.ac.uk!mole.bio.cam.ac.uk!ag24 From: ag24@mole.bio.cam.ac.uk (Aubrey de Grey) Newsgroups: bionet.molbio.ageing Subject: Re: CR MAILING LIST? Date: 23 May 1997 20:54:35 GMT Organization: University of Cambridge Message-ID: <5m506b$4jh@lyra.csx.cam.ac.uk> References: <3383a5ee.2569797@news.dial.pipex.com> NNTP-Posting-Host: mole.bio.cam.ac.uk Lines: 9 There are top CR experts among the subscribers to Longevity Digest, so I'd ask your questions there. More generally, I recommend that list to anyone interested in research on aging: it's the only moderated list on the topic that I know of (Brian Rowley, the moderator, is back from his vacation now) and the subscribers include enough specialists (though more would be very welcome!) that debates are pretty well-informed. Email listserv@vm.ege.edu.tr with "subscribe longevity-digest " in the body of the message. Aubrey de Grey From owner-ageing@net.bio.net Sat May 24 23:00:00 1997 Path: biosci!TEAM-INSPIRE.COM!mlmdream From: mlmdream@TEAM-INSPIRE.COM Newsgroups: bionet.molbio.ageing Subject: The Quest, Join Us In Our Vision Date: 25 May 1997 01:55:54 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 55 Sender: daemon@net.bio.net Distribution: world Message-ID: <199705250451.EAA29870@mail-response.com> NNTP-Posting-Host: net.bio.net ***Please type "LEADER" in the Subject area when requesting more information*** To be removed from this very specific list, Please type "REMOVE" in the Subject Area ********PLEASE READ THE FOLLOWING VERY CAREFULLY******** You have been selected to learn about what could be a real opportunity that can change your life forever (I wonder if you've heard THAT before). You were chosen from a select list of MLM leaders, and very soon we will be sending this opportunity out to the world. We desire to build our team of leaders first and YOU could very well be one of them. We are very deliberate in what we are doing and this message is just the begining!!! Our team is building very quickly and has found one of the best opportunities you could imagine. A pharmaceutical company (10 years old) and in good standing with the FDA has started a subsiduary company to market their products. They offer at this time a product line called the "BODYZONE". This is the ultimate weight management system. There is an array of products offered that help people lose weight, manage weight, boost energy, and improve their overall health. BodyPerfect has patents on these products that they themselves have developed and they cannot be obtained through any other company. They are a very professional company and have the money backing them that is needed to build this into a very large and longterm venture. They currently have only 300 people in this company but I assure you this number will explode very soon. Of this 300, there is no real Wave 3 network marketers. Our team is at the very top of this. Anyone should realize that if you join this group now that your chances are great that you will do very well. It truly is the opportunity of a lifetime. Also it is my understanding that this company has developed a transdermal weightloss patch. It is now undergoing trials with the FDA for acceptance. They expect that approval for the patch will be Feb. '98. This could be the product of the decade!! ***** I hope I have peaked your interest a little more on this opportunity.***** Now our group is comprised of some of the best leaders in the industry. We are a group of individuals that have gotten fed up of all the scams and empty promises that this industry has had to offer. There are legitimate companies and opportunities out there and we find them. One thing in life I have learned is that to make money you need to associate yourself with others that make money. That formula works every time! The money makers are here. Take advantage of the benefits our group has to offer like free webpages and great upline support like no other. We do not want troublemakers in our group. We are very selective as to whom we want in. We want people who want to make money and are team players. We are, and will always be, the best team ever. Please consider being a part of this team at the top. If you want to find out more about this opportunity just e-mail me and please give us a contact number where we can reach you. If you have a fax please send it too. I will get back to you ASAP because this is very timely and important. We do have some info on the company that we can fax but this is very very new and we are currently developing the webpages and more info to have it available as soon as we can. Thanks so much for your time and I hope you want to join us and truly change your life today. Sincerely, Roy Vision Quest Team Leader sunpaw@gte.net or mlmdream@team-inspire.com From owner-ageing@net.bio.net Sat May 24 23:00:00 1997 Path: biosci!TEAM-INSPIRE.COM!mlmdream From: mlmdream@TEAM-INSPIRE.COM Newsgroups: bionet.molbio.ageing Subject: Company Launch to Global Expansion Date: 25 May 1997 14:53:39 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 41 Sender: daemon@net.bio.net Distribution: world Message-ID: <199705251737.RAA20418@mail-response.com> NNTP-Posting-Host: net.bio.net On April 15th, 1997, a company launched its U.S. direct sales operation. They are presently negotiating markets in the Phillipines, Brazil, Argentina, and Canada. They have spent several years developing their business plan, compensation, distribution network, and sales and marketing strategies. In association with a solvent pharmaceutical corporation, they have developed or are now in the development stage, and hold world wide marketing rights to a number of unique environmental, health, and fitness products. For the past decade they have been a leader in developing and producing the highest quality Homeopathic, Herbal, Nutraceutical, Natural Pharmaceutical, and Weight Loss products. Until now these exclusive products have only been available to health care professionals. The company is initially offering a line of weight loss management products with plans to introduce several other product lines over the next 18 months that have been thorooughly researched and developed. We are committed to only introducing the highest quality products that have exceptional consumer appeal and demand. One of our initial products is the Body Zone weight management system. It is a highly specialized metabolic weight loss program that is available in 30 day supplies. We are also releasing 12 other products that compliment and/or add to this system. From the individual who is concerned with weight loss, to the competative athlete whose primary focus is muscle development and/or lean body mass, we feel this product line is superior to anything currently available. They are developing a highly sophisticated, mobile training team. They will be offering seminars and training at various locations across the country as they prepare for ultimate Global Expansion! They are currentl experiencing tremendous Growth and fully expect to be in the tens of thousands within a few short months. We are seeking Leaders who are self motivated, honest in their work, have good people skills, and are prepared for/or desire to improve their current lifestyle. Self Esteem, excitement, knowledge and understanding, opportunities for travel and fun, and the real ability to achieve the income you both deserve and desire. We are the company of your future! Please feel free to contact me, sunpaw@gte.net, if you have any questions or require additional information. You may also just hit the reply button. Also, if you do not wish to delay as I did not, send me your phone number, YOU WILL BE CONTACTED IMMIDIATELY!!! Roy Vision Quest Teal Leader From owner-ageing@net.bio.net Mon May 26 23:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!disgorge.news.demon.net!demon!dispatch.news.demon.net!demon!rill.news.pipex.net!pipex!tank.news.pipex.net!pipex!usenet From: hk05@dial.pipex.com Newsgroups: bionet.molbio.ageing Subject: Re: CR MAILING LIST? Date: Tue, 27 May 1997 07:39:22 GMT Organization: UUNet PIPEX server (post doesn't reflect views of UUNet PIPEX) Message-ID: <338a5d2f.10419854@news.dial.pipex.com> References: <3383a5ee.2569797@news.dial.pipex.com> <5m506b$4jh@lyra.csx.cam.ac.uk> NNTP-Posting-Host: ao066.du.pipex.com X-Newsreader: Forte Free Agent 1.1/16.230 Lines: 21 On 23 May 1997 20:54:35 GMT, ag24@mole.bio.cam.ac.uk (Aubrey de Grey) wrote: >There are top CR experts among the subscribers to Longevity Digest, so I'd >ask your questions there. More generally, I recommend that list to anyone >interested in research on aging: it's the only moderated list on the topic >that I know of (Brian Rowley, the moderator, is back from his vacation now) >and the subscribers include enough specialists (though more would be very >welcome!) that debates are pretty well-informed. Email listserv@vm.ege.edu.tr >with "subscribe longevity-digest " in the body of the message. Thanks Aubrey but I'm already on that list. I would recommend it though to anyone else interested in longevity issues. The material is quite well informed and has already provided me with numerous new insights on the subject. However, I am still looking for something specifically CR related. Anybody know of anything going down on the topic? Iain Whitehead. From owner-ageing@net.bio.net Tue May 27 23:00:00 1997 Path: biosci!rutgers.rutgers.edu!uwm.edu!spool.mu.edu!howland.erols.net!cliffs.rs.itd.umich.edu!newsxfer3.itd.umich.edu!feeder.chicago.cic.net!news.uiowa.edu!hardin9.lib.uiowa.edu!user From: eric-rumsey@uiowa.edu (Eric Rumsey) Newsgroups: bionet.molbio.ageing Subject: WWW: Hardin Meta Directory update - Geriatrics Date: 28 May 1997 17:57:09 GMT Organization: University of Iowa, Hardin Library for the Health Sciences Lines: 35 Message-ID: NNTP-Posting-Host: hardin9.lib.uiowa.edu This is to announce an updated version of the Hardin Meta Directory web page for Geriatrics. A *new and important feature* for Hardin MD is that we are now using a link checker to check the connection rate for the lists that are included. Generally the lists with better connection rates are toward the top of their size category (although size of the list is also a consideration in placement). Lists on the updated Hardin MD Geriatrics page with especially good connection rates include: -MedWeb: Geriatrics -Eldercare Web - Text only | Graphical, Karen S. Brown -Aging and Dementia Web Resources, Washington Univ -Medical Matrix - Geriatrics Of course, using our link checker, the links on our own pages have superlative connection rates, generally above 98%. The URL for the Hardin Meta Directory Geriatrics page is - http://www.arcade.uiowa.edu/hardin-www/md-ger.html Please check it out ! Please post this message to appropriate listservs. If you would like to receive e-mail notices for all Hardin MD updates (1-2 messages per wk), please e-mail me directly at rumsey@blue.weeg.uiowa.edu. DO NOT REPLY DIRECTLY TO THIS MESSAGE. * * * * * * * * * Eric Rumsey, Hardin Library for the Health Sciences University of Iowa, Iowa City IA 52242 319-335-9875 (voice), 319-335-9897 (fax) Hardin Meta Directory of Internet Health Sources http://www.arcade.uiowa.edu/hardin-www/md.html Reviewed in Consumer Reports, Feb 1997, p 29 From owner-ageing@net.bio.net Wed May 28 23:00:00 1997 Path: biosci!agate!newsfeed.kornet.nm.kr!nntp.kreonet.re.kr!xfer.kren.nm.kr!hammer.uoregon.edu!vixen.cso.uiuc.edu!howland.erols.net!spring.edu.tw!serv.hinet.net!netnews.hinet.net!news From: Randy Gillespie Newsgroups: sci.cryonics,bionet.molbio.ageing Subject: Re: cryonics--embalming as low-cost alternative Date: Thu, 29 May 1997 00:24:58 +0800 Organization: TRG Consulting Lines: 188 Message-ID: <338C5C59.1ECA4C8A@ms4.hinet.net> References: <5mbcl5$q2n@milo.vcn.bc.ca> Reply-To: randygillespie@internetaddress.com NNTP-Posting-Host: 168.95.230.67 Mime-Version: 1.0 Content-Type: multipart/alternative; boundary="------------37FCA8F444FAD9FF16185FED" X-Mailer: Mozilla 4.0b4 [en] (Win95; I) X-Priority: 3 (Normal) --------------37FCA8F444FAD9FF16185FED Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit multi-quote/review: > Randy Gillespie (nwibn@ms4.hinet.net) wrote: > : Subject: embalming as low-cost and technically superior alternative to > : cryo-freezing to preserve the deceased for subsequent reanimation -- > : sorry, not up with local terminology -- > : ................ > : There's the basic idea. Costwise and preservation-wise, my feeling is > : that it's got freezing beat all to gonzo. > : > With respect to costs I don't think there can be much doubt that chemical > fixation is considerably less expensive than cryonics. However fixation by > itself does not permanently preserve tissue structure. DNA in particular > is rapidly degraded at room temperature, when formaldehyde is used as a > fixative. Here's a quote from (Path. Res. Pract. 189: 66-72 1993): > "Aldehyde fixatives resulted in degradation of DNA at room temperature but > not at 4 C. The degradation also occurred in formalin when the pH or the > salt concentration was low, or the formic acid level was high." > I like to suggest therefore that chemical preservation at a minumum > needs to be combined with permafrost burial to be an effective alternative > to cryonics. The Canadian Cryonics Society has assisted in arranging such > burials in the past. If anyone is interested please contact either myself > (oberon@vcn.bc.ca) or Ben Best at (benbest@benbest.com). > I should also mention that current embalming procedures do not properly > fix human corpses since far too little formaldehyde is used for this. Thus > special preparations are required for good tissue preservation to occur. > -----------------end quote----------------- OK, permafrost (or some momma nature cheapo equiv refrigerator), yeah, makes sense for sure, but it still ain't cheap if you live in a shabby apartment in Los Angeles or Shanghai. Grandpa in a baggy in the attic or garage, possibly even six feet under trad-wise, that's at least a deal in terms of initial transportation, 'cept for Eskimos. Well, hey . . . 77.3 years hence, we decide to bring granpa back and see what he's good for . . . and he was an early embalm job . . . DNA and the rest in not-good shape . . . not even one intact DNA copy left . . . NO PROBLEM . . . for several reasons!!! 1) A whole lot of rather randomly distorted DNA copies can be "averaged" back into a pristine original (especially when the basic human genome is a stock model, with some local customization . . . and we got the plans for the stock model). 2) More importantly, it's significantly unlikely that grandpa would want a pristine copy of his original specs---he was reaching for the future, at least in part, to escape the tyranny of a genetic design he had no choice over and a heck of a lot of consumer complaints about. Instead, we upgrade his DNA while we're reanimating and rejuvenating (growing his body young) him. If he turns out to be a back-to-nature freak of the bizarre intensity level, well, he can go to the trouble of converting back to his stock specs later, on his own time, if we don't burn the data collected during reani-rejuv prep. But if granpa is gonna be granpa and not a related piece of hamburger with a stranger inside, we gotta preserve a workable map of the nervous system. This means a two level map. First level is general nerve wiring. Second is related to various substructure, such as the general number of certain proteins at a given neural junction. It doesn't matter if the proteins themselves are dysfunctional. Custom repair enzymes can handle that, if they can recognize the protein (or whatever) so they know what to build it back into and know where to leave it. Unlike freezing, which causes highly random damage, room temperature "rotting" is rather regular (especially if suitably embalmed and protected from things that think we're just a jolly chunk of junk food) . . . so our clever custom repair enzyme (one of quite a few . . . you can see the list on the computer if you want) sees a standard-damage xyz-sigma-wowserase with the typical extra oxygen here, the cross-link there, the standard break at the left turn next to the 3'rd hydroxyl, etc, and sez "Well, about this extra oxygen, now I gotta . . ." and on into its program.. The main thing we gots to do is keep a statistically adequate map of granpa's pieces for an adequate time. I say "statistically" cause that's all you are anyway. Your moment to moment and minute to minute, not to mention day to day, well, a walking average, kinda, you know? If you want to go higher tech on this in latin or something, OK, but it's kinda square and no more meaningful, though the polysyllabic horse exhaust impresses the hoople out of the peasants and the pseuds. So, in the words of the presumably already dead and burned or rotted Stan Lee (sorry Stan, but I ain't been keeping notes), 'Nuff Said --------------37FCA8F444FAD9FF16185FED Content-Type: text/html; charset=us-ascii Content-Transfer-Encoding: 7bit multi-quote/review: 
Randy Gillespie (nwibn@ms4.hinet.net) wrote:
: Subject:  embalming as low-cost and technically superior alternative to
: cryo-freezing to preserve the deceased for subsequent reanimation  --
: sorry, not up with local terminology --
: ................ 
: There's the basic idea.  Costwise and preservation-wise, my feeling is
: that it's got freezing beat all to gonzo.
: 
 With respect to costs I don't think there can be much doubt that chemical
fixation is considerably less expensive than cryonics. However fixation by
itself does not permanently preserve tissue structure. DNA in particular
is rapidly degraded at room temperature, when formaldehyde is used as a
fixative. Here's a quote from (Path. Res. Pract. 189: 66-72 1993):
"Aldehyde fixatives resulted in degradation of DNA at room temperature but
not at 4 C. The degradation also occurred in formalin when the pH or the
salt concentration was low, or the formic acid level was high."
  I like to suggest therefore that chemical preservation at a minumum 
needs to be combined with permafrost burial to be an effective alternative
to cryonics. The Canadian Cryonics Society has assisted in arranging such
burials in the past. If anyone is interested please contact either myself
(oberon@vcn.bc.ca) or Ben Best at (benbest@benbest.com).
  I should also mention that current embalming procedures do not properly
fix human corpses since far too little formaldehyde is used for this. Thus
special preparations are required for good tissue preservation to occur.
-----------------end quote-----------------

OK, permafrost (or some momma nature cheapo equiv refrigerator), yeah, makes sense for sure, but it still ain't cheap if you live in a shabby apartment in Los Angeles or Shanghai.  Grandpa in a baggy in the attic or garage, possibly even six feet under trad-wise, that's at least a deal in terms of initial transportation, 'cept for Eskimos.

Well, hey . . . 77.3 years hence, we decide to bring granpa back and see what he's good for . . . and he was an early embalm job . . . DNA and the rest in not-good shape . . . not even one intact DNA copy left . . . NO PROBLEM . . . for several reasons!!!

    1)  A whole lot of rather randomly distorted DNA copies can be "averaged" back into a pristine original (especially when the basic human genome is a stock model, with some local customization . . . and we got the plans for the stock model).

    2)  More importantly, it's significantly unlikely that grandpa would want a pristine copy of his original specs---he was reaching for the future, at least in part, to escape the tyranny of a genetic design he had no choice over and a heck of a lot of consumer complaints about.  Instead, we upgrade his DNA while we're reanimating and rejuvenating (growing his body young) him.  If he turns out to be a back-to-nature freak of the bizarre intensity level, well, he can go to the trouble of converting back to his stock specs later, on his own time, if we don't burn the data collected during reani-rejuv prep.

But if granpa is gonna be granpa and not a related piece of hamburger with a stranger inside, we gotta preserve a workable map of the nervous system.  This means a two level map.  First level is general nerve wiring.  Second is related to various substructure, such as the general number of certain proteins at a given neural junction.  It doesn't matter if the proteins themselves are dysfunctional.  Custom repair enzymes can handle that, if they can recognize the protein (or whatever) so they know what to build it back into and know where to leave it.  Unlike freezing, which causes highly random damage, room temperature "rotting" is rather regular (especially if suitably embalmed and protected from things that think we're just a jolly chunk of junk food) . . . so our clever custom repair enzyme (one of quite a few . . . you can see the list on the computer if you want) sees a standard-damage xyz-sigma-wowserase with the typical extra oxygen here, the cross-link there, the standard break at the left turn next to the 3'rd hydroxyl, etc, and sez "Well, about this extra oxygen, now I gotta . . ." and on into its program..

The main thing we gots to do is keep a statistically adequate map of granpa's pieces for an adequate time.  I say "statistically" cause that's all you are anyway.  Your moment to moment and minute to minute, not to mention day to day, well, a walking average, kinda, you know?

If you want to go higher tech on this in latin or something, OK, but it's kinda square and no more meaningful, though the polysyllabic horse exhaust impresses the hoople out of the peasants and the pseuds.

So, in the words of the presumably already dead and burned or rotted Stan Lee (sorry Stan, but I ain't been keeping notes),

'Nuff Said --------------37FCA8F444FAD9FF16185FED-- From owner-ageing@net.bio.net Thu May 29 23:00:00 1997 Path: biosci!aol.com!DENFIN From: DENFIN@aol.com Newsgroups: bionet.molbio.ageing Subject: sub Date: 30 May 1997 05:33:41 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 1 Sender: daemon@net.bio.net Distribution: world Message-ID: <970530083406_22392492@emout11.mail.aol.com> NNTP-Posting-Host: net.bio.net Subscribe ageing Dennis Fink