From owner-software@net.bio.net Sun Nov 01 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!swrinde!sdd.hp.com!usc!snorkelwacker.mit.edu!bloom-picayune.mit.edu!wccf.mit.edu!karuzis
From: karuzis@wccf.mit.edu (GLENN HOLM)
Newsgroups: bionet.software
Subject: Re: NeXT and biology, anyone?
Message-ID: <1NOV199218384640@wccf.mit.edu>
Date: 1 Nov 92 23:38:00 GMT
References: <921031131619.2380ba74@CCSUA.CTSTATEU.EDU>
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In article <921031131619.2380ba74@CCSUA.CTSTATEU.EDU>, LETTIERE_DAJ@CCSUA.CTSTATEU.EDU writes...
>Hello,
> 
>	I am wondering if there is any biology software in existance for the 
>NeXT computer.  I would prefer to see public domain (e.g. free) software but 
>would be interested in commercial packages as well.  In addition, are there any 
>ftp sites with biology software for the Sun?
>	
> 
>				Thanks in advance
> 
>				Dan Lettiere
> 
>********************************************************************************
>E-Mail: lettiere_daj@ccsu.ctstateu.edu
> 
>Snail Mail: Central Connecticut State University
>	    Dept. of Biological Sciences, Copernicus Hall
>	    1615 Stanley Street
>	    New Britain, CT 06050
>********************************************************************************
>^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
> 

The following just appeared in comp.sys.next.misc:

Path: bloom-picayune.mit.edu!enterpoop.mit.edu!snorkelwacker.mit.edu!tamsun.tamu.edu!cs.utexas.edu!zaphod.mps.ohio-state.edu!caen!uunet!rosie!NeXT.com
From: Conrad_Geiger@NeXT.com (Conrad Geiger - Manager, International NeXT User Groups)
Newsgroups: comp.sys.next.misc
Subject: NeXT Education Software Sampler: CD-ROM Software Compendium
Message-ID: <5686@rosie.NeXT.COM>
Date: 31 Oct 92 00:10:24 GMT
Sender: news@NeXT.COM
Reply-To: user_groups@next.com
Lines: 79

News

FOR IMMEDIATE RELEASE

Contact:	Angela Grady
		Allison Thomas Associates
		(415) 780-3786

Announcing:
NeXT(tm) Education Software Sampler: CD-ROM Software Compendium


BALTIMORE, October 28, 1992 -- At the EDUCOM'92 conference today,
NeXT Computer, Inc. announced the availability of the first NeXT
Education Software Sampler, a CD-ROM containing a wide assortment of
public domain shareware education software for NeXTSTEP(tm)
computers.

"Our goal with the NeXT Education Software Sampler is to provide
users with useful, easily accessible software as well as to stimulate
users' imaginations by providing ideas for further development with
NeXTSTEP," said David Spitzler, higher education marketing manager
for NeXT.  "Because all the software on the disc was submitted to
NeXT specifically for redistribution, we encourage users to share
anything on the Software Sampler with others who may be interested in
educational NeXTSTEP software."

Most of the software on the CD-ROM is ready to run and can be used
free of charge.  The software was submitted by faculty, researchers
and students as well as representatives from various industries.  The
disc also contains demonstration versions of a variety of
commercially available applications, submitted by the third-party
developers themselves.  In addition, NeXT has also included the
source code of its modifications to the Free Software Foundation's
GNU-based development tools, including the compilers, debugger and
the emacs editor.

Examples of education software on the disc include FlyLab, an
application written for an introductory genetics course at the
California State University at Los Angeles.  Fly Lab teaches the
principles of genetic inheritance by simulating a genetics laboratory
of the common fruit fly.  Students can design flies that carry
various combinations of mutations, then "mate" the flies to study the
inheritance of genetic traits in the offspring.  Other examples
include Geo4 and Geo5, software for teaching and learning historical
geography, written at St. Mary's College of Maryland, and a
demonstration of Tarski's World, an application for learning
first-order logic written at Stanford University.

Organized into sections by subject, the CD-ROM contains more than 500
megabytes (MB) of applications, utilities, documents and much more.
For instance, the disc includes nearly 15 MB of music software, more
than 70 MB of mathematics software and almost 80 MB of programming
examples and source code from full-functioning applications.  Each
submission includes a README file with minimum standard information
about the application and who to contact for more information.

Price and Availability
The NeXT Education Software Sampler is available now directly from
NeXT for $25.00.  Interested parties can call 1-800-879-NeXT to
order.


About NeXT Computer, Inc.
NeXT Computer, Inc. designs and markets the industry-acclaimed
NeXTSTEP object-oriented operating system, and designs, manufactures
and markets UNIX-based workstations that run NeXTSTEP.  NeXTSTEP and
NeXT workstations are used by medium and large organizations to
develop and deploy mission-critical applications, using both custom
and shrink-wrapped software.  NeXT is headquartered at 900 Chesapeake
Drive, Redwood City, Calif., 94063.

-30-


NeXT, the NeXT logo and NeXTSTEP are trademarks of NeXT Computer,
Inc.  All other trademarks mentioned belong to their respective
owners.



------------------------------------------------------------------
|Glenn Holm                         Internet:karuzis@wccf.mit.edu|
|M.I.T Dept. of Brain + Cog. Sci.   This VAX doesn't do NeXTmail |
|Cambridge, MA 02139       "Real Neuroscientists don't do gels!" |
------------------------------------------------------------------

From owner-software@net.bio.net Sun Nov 01 22:00:00 1992
Path: biosci!uwm.edu!cs.utexas.edu!uunet!munnari.oz.au!ariel.ucs.unimelb.EDU.AU!ucsvc.ucs.unimelb.edu.au!lugb!lure.latrobe.edu.au!extim
From: extim@lure.latrobe.edu.au
Newsgroups: bionet.software
Subject: Info on Waters Millenium HPLC software?
Message-ID: <1992Nov2.173418.1@lure.latrobe.edu.au>
Date: 2 Nov 92 07:34:18 GMT
Sender: news@lugb.latrobe.edu.au (USENET News System)
Organization: VAX Cluster, Computer Centre, La Trobe University
Lines: 75

Dear HPLC specialists,

We are considering the purchase of the Waters Millenium software
(2010 Multisystem with Bus LAC/E card) and our own computer system
consisting of a clone 486DX/33, 16 Meg memory, 200 Meg HD, SVGA.
This system will be used for the control of two simple gradient
systems. What follows is a request for information about the
performance of this equipment. We have had experience in running
gradient systems with WISP by Maxima for multiple sample analysis.

One system will be formed of a simple Waters UV detector (481)
Waters 710 WISP and will be used for analysis of samples for
ivermectin either by an isocratic or simple gradient protocol. For
this we need the ability to reliably perform and store overnight runs
and the ability to re-integrate unsatisfactory runs.

The software will also be used to control a gradient system for
research uses based around a standard injector and a Waters
996 photodiode array.

At present, none of the equipment has instrumentation interfaces
so one of the decisions we have to make is what method to connect
to Millenium, through either IEEE or SIM.

To build this system within budget (actually trying to keep the
overbudget to within $10,000) we are trying to keep everthing to
a minimum. To try and find out what is possible we have limited 
sources of information. First the Waters reps out here seem to
be on a significant learning curve (or have some commercial interests
to push) and a limited number of users. We have been getting
conflicting info so I would be gratefull if anyone out there who is
using Millenium could perhaps clarify some matters.

Will Millenium control either IEEE or SIM interfaces or both?
(The Millenium manuals seem to suggest that SIM control is not 
possible, but people are using it with SIMs)

Is the IEEE route significantly faster or has other major benefits
worth $2,000 extra?

How stable have you found the system?
(Our contacts report system lockups with version 1.0)

Is the overall performance sufficient to allow the control
of two gradient systems?
(We are told that the system is highly dependent on the absolute
maximum performance of the computer system else long waits even
with ordinary gradients)

Are these performance problems going to be much worse if significant
use is made of the PDA?

Is it possible to manually integrate?
(One group reports that Waters reps were unable to get that
section of the program to manually integrate runs)

There is some confusion as to the initial flow rates that are
allowed. Either zero flow rates are not allowed as the first
commands in programmes, or that the software will not start a
pump from zero flow?

A lot of questions!
Some of these we are hoping to get sorted out by more detailed
questioning here. However we need to make some decisions soon and
some other imputs will be valuable.

Thanks for any assistance.

Ian McCauley
Department of Biochemistry
Victorian Institute of Animal Science
Melbourne, Australia

AARNET ... extim@lure.latrobe.edu.au.oz
or ....... mccauleyi@agvic.gov.au.oz (much less reliable at present)

From owner-software@net.bio.net Sun Nov 01 22:00:00 1992
Path: biosci!agate!ames!think.com!hsdndev!nmr-z!OPAL.MGH.HARVARD.EDU!CHERRY
From: cherry@OPAL.MGH.HARVARD.EDU
Newsgroups: bionet.software
Subject: Re: Sequence databases on the network
Message-ID: <1992Nov2.040633.14679@nmr-z.mgh.harvard.edu>
Date: 2 Nov 92 04:06:33 GMT
References: <9210281920.AA24061@phage.cshl.org>,<1992Oct31.153502.15279@comp.bioz.unibas.ch>
Sender: usenet@nmr-z.mgh.harvard.edu (User for USENET news postings)
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>In article <1992Oct31.153502.15279@comp.bioz.unibas.ch>, doelz@comp.bioz.unibas.ch (Reinhard Doelz) writes:
>>There are a variety of sources which can be used to download sequence 
>>databases (full releases) via FTP. I find this procedure tolerable on 
>>local or may be national networks, but it is definitively overkill 
>>on international lines. I am currently providing Swissprot and EMBL in generic, 
>>as well all other databases in GCG/PIR format.  If the usage of FTP'ing 
>>these databases outside of Switzerland continues as it did in the past 
>>(e.g., EMBL was downloaded by more than 18 sites, five of them being 
>>information providers, which is okay, but the rest were sites who wanted 
>>to "save money", or didn't know about a resource on their national net), 
>>we will be forced to close down this way of access for international networks. 

An alternative location to obtain the least EMBL database and updates
via anonymous ftp is amber.mgh.harvard.edu [IP 132.183.191.26].  This
archive is open to all and is encouraged for sites outside of
Switzerland. Amber is a VMS system so the compressed EMBL flat files
are in the form: "xxx.dat_z". If you are running Unix you might need to
rename the files to the form: "xxx.dat.Z".

Weekly updates of EMBL are of available in two compressed flat files:

    xembl.flat_z      additions to EMBL since the last release
    xxembl.flat_z     modifications of sequences in the release

All of the above files are obtained direct from the Swiss EMBnet node
and are provided thanks to Reinhard Doelz.

Remember that compressed files should be transferred as binary. Also
available on Amber are VMS savesets of the EMBL database minus those
sequences already in GenBank. These are produced using the latest
GenBank database from ncbi.nlm.nih.gov plus daily updates and the GCG
EMBLtoGCG/EXCLUDE command.

Mike Cherry
cherry@frodo.mgh.harvard.edu

From owner-software@net.bio.net Sun Nov 01 22:00:00 1992
Path: biosci!CU.NIH.GOV!CZJ
From: CZJ@CU.NIH.GOV
Newsgroups: bionet.software
Subject: Re:  Looking for hydrophob.  plot & helical wheel soft
Message-ID: <9211020347.AA06036@net.bio.net>
Date: 2 Nov 92 02:10:51 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 29

> In <KH.92Oct29162939@litsun17.epfl.ch> kh@litsun17.epfl.ch (Mark S.) writes:
>
> >Hello All,
>
> >this might very well be a FAQ, ...
>
> >but I am looking for software to do helical wheel plots and hydrophobicity plots. Does anyone have an idea where to grab this kind of soft?
> >Or is there someone who has tried a package?
>
> GCG should be able to do this (if you have access to it). I just mention
> this because I assume that anybody working in the molbiol/biochemistry
> sector might have access to it. If you want to run the program(s) on a
> personal computer instead, it would be a great help for others if you'd
> specify the type of computer you're working with (and in some special
> cases -- such as IBM compatibles running UNIX -- the operation system
> as well).
> --
> /* Cornelius Krasel, Department of Physiological Chemistry, U Tuebingen    */
> /* email: krasel@studserv.zdv.uni-tuebingen.de (Internet)   HAS CHANGED!!  */
> /*        krasel@student.uni-tuebingen.dbp.de (WIN/X400)    HAS CHANGED!!  */
> /* "People are DNA's way of making more DNA." (anonymous)                  */
>
>

Prograph does all of this.  Prograph is available from the embl
file server and other FTP sites.  Prograph runs on DOS machines.

Jim Cassatt


From owner-software@net.bio.net Mon Nov 02 22:00:00 1992
Path: biosci!news.cs.indiana.edu!usenet.ucs.indiana.edu!sol.ctr.columbia.edu!caen!batcomputer!genie!olivea!sgigate!rutgers!utcsri!torn!news.ccs.queensu.ca!!BACKD@QUCDN.QueensU.CA
From: BACKD@QUCDN.QueensU.CA@
Newsgroups: bionet.software
Subject: Re: full sequence of pCR II from Invitrogen ?
Message-ID: <BACKD@QUCDN.QueensU.CA.33@>
Date: 3 Nov 92 01:41:24 GMT
References: <1cqqcdINN87r@uniwa.uwa.edu.au>
Sender: news@knot.ccs.queensu.ca (Netnews control)
Organization: Queen's University, Kingston
Lines: 16

In article <1cqqcdINN87r@uniwa.uwa.edu.au> robert@arbo.microbiol.uwa.oz.au (Robert Coelen) writes:

>Hi,

>could anyone out there, who is in possession of the full sequence of 
>pCR II from InVitrogen email it to me ?

>Thanks

>Robert Coelen
>Dept of Microbiology

INVITROGEN has placed all of their sequences on a bulletin board.
You can down load from (619) 597-6230 8-1-n

Good luck

From owner-software@net.bio.net Mon Nov 02 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!wupost!sdd.hp.com!nigel.msen.com!caen!saimiri.primate.wisc.edu!ames!agate!doc.ic.ac.uk!uknet!pavo.csi.cam.ac.uk!mbfs.bio.cam.ac.uk!seb1005
From: seb1005@mbfs.bio.cam.ac.uk (Steven Brenner)
Newsgroups: bionet.software
Subject: Looking for Protein Threading & Design Software, EMBL Documents
Message-ID: <1992Nov3.000919.24583@infodev.cam.ac.uk>
Date: 3 Nov 92 00:09:19 GMT
Sender: news@infodev.cam.ac.uk (USENET news)
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Nntp-Posting-Host: mbfs.bio.cam.ac.uk

I would appreciate if if anyone could tell me where I could find any of the
following programs, or if they tell me how to contact the authors by
electronic mail.

predipep
described in 
Goraj et al, Protein Engineering 3:4 259-266 (1990)
Universite de Liege, Insitut de Chimie (Belgium)

structure alignment program
described in
Orengo et al, Proteins 14 139-167 (1992)
National Institute for Medial Research, London (now at University College, London)

threading program
described in 
Jones et al, Nature v358 p86 (1992)
University College, London

3D-1D (threading-type) program
described in
James Bowie et al, Science 253 p164-170 (1992)
UCLA

STAMP
described in
Russel & Barton, Proteins v14 309-323 (1992)
Oxford

Patchcharge
described in
Karpeisky & Illyin, J Mol Bio 224 629-638 (1992)
USSR Academy of Sciences

Also, does anyone know where the EMBL BIOcomputing Technical Documents can be
found?  The libraries here at Cambridge have never heard of them.  

Finally (as long as I'm posting) does anyone know the email or letter-mail 
address for Chris Sander, Marc Eberhard, Arne Elofsson, Tim JP Hubbard, & Lynne 
Regan?  They are 5 of some  two dozen authors of a paper which doesn't list
individual addresses

Thanks in advance for your collective help!

Steven Brenner
seb1005@mbfs.bio.cam.ac.uk

Department of Biochemistry
University of Cambridge

From owner-software@net.bio.net Mon Nov 02 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!swrinde!zaphod.mps.ohio-state.edu!sol.ctr.columbia.edu!spool.mu.edu!hri.com!noc.near.net!news.bbn.com!hsdndev!golgi.harvard.edu!ribo!rindone
From: rindone@ribo.harvard.edu (Wayne Rindone)
Newsgroups: bionet.software
Subject: Re: Protein Structure: Internal coords --> PDB
Keywords: Protein, Conversion, Coordinates, PDB, Dihedral_angles
Message-ID: <rindone.720737468@ribo>
Date: 2 Nov 92 20:51:08 GMT
References: <Bwwzo5.J15@acsu.buffalo.edu>
Sender: news@golgi.harvard.edu
Distribution: bionet
Organization: Harvard Genome Laboratory
Lines: 46
Nntp-Posting-Host: ribo


v071rw4p@UBVMSB.CC.BUFFALO.EDU (EMIL MARCUS) writes:


>     I would be most grateful if you could help me locate a program that
>converts protein internal (dihedral angles: phi, psi, omega, chi's...)
>coordinate files into cartesian - PDB (Protein Data Bank) type files !
>     The program that does the reverse transformation is available from
>The Protein Data Bank...  

>Thank you,
>Emil
>--------

>     Emil Marcus  V071RW4P@ubvms.cc.buffalo.edu    MARCUS@acsu.buffalo.edu

     One software package that might be useful in this regard is the
NIH-sponsored Prophet system for a variety of Unix workstations.

     Prophet includes an interactive procedure called makepolypeptide
that constructs a three dimensional structure from a series of amino
acid names, phi angles, and psi angles. It does not explicitly offer
prepackaged control over the omega and chi angles (all the omegas are
set to 180 degrees, chi angles are whatever was found in the template
residues). However, what is created is a Prophet molecule, for which
there are a variety of techniques, including interactive pointing as
well as procedure calls, for modifying torsion angles and other
geometric parameters. Prophet does know how to create a PDB-formatted
file for any Prophet molecule. 

     More information about Prophet can be obtained by sending email
to prophet-info@bbn.com

**************************************************************************
Wayne Rindone
FlyBase
Department of Cellular and Developmental Biology
Harvard University
rindone@nucleus.harvard.edu
**************************************************************************

-- 
**************************************************************************
Wayne Rindone
FlyBase
Department of Cellular and Developmental Biology

From owner-software@net.bio.net Mon Nov 02 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!swrinde!zaphod.mps.ohio-state.edu!sol.ctr.columbia.edu!spool.mu.edu!hri.com!noc.near.net!news.bbn.com!hsdndev!golgi.harvard.edu!ribo!rindone
From: rindone@ribo.harvard.edu (Wayne Rindone)
Newsgroups: bionet.software
Subject: Re: Protein Structure: Internal coords --> PDB
Keywords: Protein, Conversion, Coordinates, PDB, Dihedral_angles
Message-ID: <rindone.720736244@ribo>
Date: 2 Nov 92 20:30:44 GMT
References: <Bwwzo5.J15@acsu.buffalo.edu>
Sender: news@golgi.harvard.edu
Distribution: bionet
Organization: Harvard Genome Laboratory
Lines: 44
Nntp-Posting-Host: ribo

v071rw4p@UBVMSB.CC.BUFFALO.EDU (EMIL MARCUS) writes:


>     I would be most grateful if you could help me locate a program that
>converts protein internal (dihedral angles: phi, psi, omega, chi's...)
>coordinate files into cartesian - PDB (Protein Data Bank) type files !
>     The program that does the reverse transformation is available from
>The Protein Data Bank...  

>Thank you,
>Emil
>--------

>     Emil Marcus  V071RW4P@ubvms.cc.buffalo.edu    MARCUS@acsu.buffalo.edu

     One software package that might be useful in this regard is the
NIH-sponsored Prophet system for a variety of Unix workstations.

     Prophet includes an interactive procedure called makepolypeptide
that constructs a three dimensional structure from a series of amino
acid names, phi angles, and psi angles. It does not explicitly offer
prepackaged control over the omega and chi angles (all the omegas are
set to 180 degrees, chi angles are whatever was found in the template
residues). However, what is created is a Prophet molecule, for which
there are a variety of techniques, including interactive pointing as
well as procedure calls, for modifying torsion angles and other
geometric parameters. Prophet does know how to create a PDB-formatted
file for any Prophet molecule. 

     More information about Prophet can be obtained by sending email
to prophet-info@bbn.com

**************************************************************************
Wayne Rindone
FlyBase
Department of Cellular and Developmental Biology
Harvard University
rindone@nucleus.harvard.edu
**************************************************************************
-- 
**************************************************************************
Wayne Rindone
FlyBase
Department of Cellular and Developmental Biology

From owner-software@net.bio.net Tue Nov 03 22:00:00 1992
Path: biosci!daresbury!news
From: Fergus_Doherty@vme.nott.ac.uk
Newsgroups: bionet.software
Subject: GCG X-windows version
Message-ID: <1992Nov4.132019.1590@gserv1.dl.ac.uk>
Date: 4 Nov 92 13:20:21 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 3
Original-To: bio-soft@uk.ac.daresbury

Hello, does nyone have any experience with the X-windows version of the 
GCG package.  Is it much easier to use than then[D standard version?
Fergus Doherty, Biochemistry, Nottingham University.

From owner-software@net.bio.net Tue Nov 03 22:00:00 1992
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: IUBio Archive biology data searches via WAIS and Gopher
Message-ID: <Bx7MHx.GJG@usenet.ucs.indiana.edu>
Date: 4 Nov 92 21:03:33 GMT
Sender: news@usenet.ucs.indiana.edu (USENET News System)
Organization: Biology, Indiana University - Bloomington
Lines: 168
Nntp-Posting-Host: sunflower.bio.indiana.edu


This is a summary of new biology data searching and retrieval offerings
at the IUBio Archive (Internet host ftp.bio.indiana.edu).  These
data are now available via a Wide Area Information Server, WAIS, as
well as via Internet Gopher.


General WAIS source to
IUBio Archive of Biology software and data
------------------------------------------

(:source 
   :version  3 
   :ip-address "129.79.224.25"
   :ip-name "ftp.bio.indiana.edu"
   :tcp-port 210
   :database-name "INFO"
   :cost 0.00 
   :cost-unit :free 
   :maintainer "archive@bio.indiana.edu"
   :description "
This WAIS service includes several indexed Biology information sources,
including Genbank nucleic acid gene sequence databank, Drosophila genetics
BioSci/Bionet network news, and others. 

     = = = = = = = = = = = = = = = = = = = = = = = =

This WAIS service sports several zippy modifications.  These include
boolean operators 'and' and 'not', partial word matches,
literal phrase matches, and extended number of results.

Boolean searches: The terms 'and' and 'not' are effective 
    in modifying the query.   For example,
    
    Query: red and green not blue
    Result: just those records with both the words 'red' and 'green',
            excluding all records with the word 'blue'.
            
Partial words:  The asterisk (*) applied at the end of
    a partial word will match all documents with words that 
    start with the partial word.  For example,
    
    Query: hum*
    Result: all records with 'hum', 'hummingbird', 'human',
            'humbug', etc.
            
Literal phrases:  If quotes (') or double quotes (\") surrounding
     a phrase, it will match that phrase exactly.  For example,
     
     Query: 'red rooster-39'
     Result:  only those records with the the full string
            'red rooster-39' will be matched.
     
These features can generally be mixed in a query, for example:
     Query:  'Df(32)-[34]red' and hum* not Brown

Results limit (Gopher only):  The maximum number of results that 
     are returned for a query is by default up to 100. 
     But you may set a higher, or lower, maximum by appending
     the greater than (>) symbol immediately followed by the
     number you wish at the end of your query.  For example,
     
     Query:  brown and cow* or "red rooster" >300
     Result:  up to 300 matches will be returned.
     
The program source to these modifications will be available via
Internet Gopher or anonymous ftp to ftp.bio.indiana.edu, in
folder IUBio Software+Data/util/wais/ as iubio-wais-8b5.tar.Z
(full source) or iubio-wais-8b5.tar.patches  for a difference or
patch file.  (This is not ready as of 4Nov92).
"
)


Short list of current IUBio Archive WAIS sources
------------------------------------------------
(Note: These searches are also available via Internet Gopher
to ftp.bio.indiana.edu)

   :database-name "arcdocs"
   :description "
This is an index of abstracts, readme, help and related information
on the IUBio Archive of Biology Software and Data.  It is updated
approximately monthly.  Files described in these documents are
generally available via ftp or gopher to ftp.bio.indiana.edu.

   :database-name "fly-address"
   :description "
This is an index of the addresses for Drosophila researchers

   :database-name "fly-amero"
   :description "
Cytological features database.
This is a database of polytene chromosome sites that have been found to
bind antibodies to particular Drosophila proteins.

   :database-name "fly-clones"
   :description "
This is an index of UCLA DROSOPHILA GENMAPS DATABASE

   :database-name "fly-din"
   :description "
This is an index of the electronic Drosophila Information Newsletter.

   :database-name "flybase"
   :description "
This is an index of the Drosophila database, FlyBase, as maintained
by Micheal Ashburner.

   :database-name "flystock-bg"
   :description "
This is an index of the Drosophila fruitfly stocks maintained
by the stock center at Bowling Green USA.

   :database-name "flystock-bl"
   :description "
This is an index of the Drosophila fruitfly stocks maintained
by the stock center at Bloomington USA.

   :database-name "flystock-um"
   :description "
This is an index of the Drosophila fruitfly stocks maintained
by the stock center at Umea Sweden.

   :database-name "genbank"
   :description "
This is an index of the Genbank databank of gene sequences:
Genetic Sequence Data Bank, NCBI-GenBank Flat File Release 73.1
86626 loci, 110208764 bases, from 86626 reported sequences

   :database-name "gbnew"
   :description "
This is an index of updates sinces the latest full release of Genbank,
the databank of all known gene sequences. It is updated weekly 
from the update files maintained by NCBI at ncbi.nlm.nih.gov.  

   :database-name "journals"
   :description "
This is an index of the table of contents of several biology
journals. 

   :database-name "methods"
   :description "
This is an index of a collection of materials and methods recipes
for molecular biologists.  

   :database-name "netnews"
   :description "
This is an index of news articles from the BioSci/Bionet newsgroups,
as well as the Sci.Bio Usenet group and the bitnet.listserv.info-gcg
group.  

   :database-name "prosite"
   :description "
This is an index of the PROSITE dictionary of protein sites and 
patterns, as produced by Amos Bairoch.

   :database-name "redbook"
   :cost 0.00 
   :cost-unit :free 
   :maintainer "archive@bio.indiana.edu"
   :description "
This is an index of the book 'The Genome of Drosophila melanogaster'
by Dan Lindsley and Georgina Zimm.

-- 
Don Gilbert                                     gilbert@bio.indiana.edu
biocomputing office, biology dept., indiana univ., bloomington, in 47405

From owner-software@net.bio.net Tue Nov 03 22:00:00 1992
Path: biosci!SALK-SC2.SDSC.EDU!mangalam
From: mangalam@SALK-SC2.SDSC.EDU
Newsgroups: bionet.software
Subject: Re: IUBio Archive biology data searches via WAIS and Gopher
Message-ID: <9211042322.AA11207@net.bio.net>
Date: 4 Nov 92 23:22:50 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 34

Don Gilbert modestly writes (on bio-soft):

>This is a summary of new biology data searching and retrieval offerings
>at the IUBio Archive (Internet host ftp.bio.indiana.edu).  These
>data are now available via a Wide Area Information Server, WAIS, as
>well as via Internet Gopher.
 
 (much text deleted - read [and save!] his previous posting for the full
report - basically announces the availability of boolean searches of
genbank entries by gopher)

   Caramba!  The biological community now has a virtual replacement for the
IRX system!  And one person wrote much of both ends of it - everyone owes
DG a noisy round of cheers and hurrahs!
   Throw out your Genbank CDs, archive your databases, unsubscribe from the
various proprietary databases.  Don just saved an awful lot of people
viewing this message a lot of money and disk space.

   Incidentally, we are examining the possibility of setting up a similar
gopher hole on the west coast.  What are your favorite databases?  What
kind of access would you like?  Gopher? FTP? WAIS? All of the above?  Let
me know so we can get an idea of what kind of resources will have to be
dedicated to it.

Cheers,

Harry

Harry Mangalam                                   Vox:(619) 453-4100, x250
Dept of Biocomputing                                   Fax:(619) 552-1546
The Salk Institute                             mangalam@salk-sc2.sdsc.edu
10010 N Torrey Pines Rd                        mangalam@salk-sgi.sdsc.edu
La Jolla CA 92037                                    mangalam@salk.bitnet


From owner-software@net.bio.net Tue Nov 03 22:00:00 1992
Path: biosci!daresbury!news
From: angelos@igmors.ups.circe.fr (Angelos Kalogeropoulos)
Newsgroups: bionet.software
Subject: GCG-X-Windows
Message-ID: <1992Nov4.134218.2539@gserv1.dl.ac.uk>
Date: 4 Nov 92 14:43:38 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 17
Original-To: bio-software@uk.ac.daresbury
Original-Sender: angelos <angelos@fr.circe.ups.igmors>

In addition to Fergus Doherty question:

>Hello, does nyone have any experience with the X-windows version of the
>GCG package.  Is it much easier to use than then standard version?

	I ask if a X-windows version exists.

	Many thanks

                  ******************************************
                  *         Angelos KALOGEROPOULOS         *
                  * Institut de Genetique et Microbiologie *
                  *              Batiment 400              *
                  *      Centre Universitaire d'Orsay      *
                  *       91405 Orsay Cedex, France        *
                  *      Angelos@igmors.ups.circe.fr       *
                  ******************************************

From owner-software@net.bio.net Wed Nov 04 22:00:00 1992
Path: biosci!LILLY.COM!SMITH_DENNIS_P
From: SMITH_DENNIS_P@LILLY.COM ("DENNIS P. SMITH")
Newsgroups: bionet.software
Subject: Graphing Program
Message-ID: <01GQRLSU3G6Q8WW08H@INET.D48.LILLY.COM>
Date: 5 Nov 92 01:34:35 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 9

I looking for a MACINTOSH graphing program to plot receptor binding data. I
have tried DeltaGraph Pro but it cannot graph the x-axis (peptide
concentration) as 10 to the negative power. How do people plot the graphs
pictured in published journals? Thanks DPSMITH
			INTERNET:smith_dennis_p@lilly.com 

From: SMITH DENNIS P                (MCVAX0::BOOKS)

To:   VMS MAIL ADDRESSEE            (INT::"bio-soft@genbank.bio.net")

From owner-software@net.bio.net Wed Nov 04 22:00:00 1992
Path: biosci!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software,bionet.announce
Subject: Drosophila database searches thru Gopher and WAIS
Message-ID: <Bx77pr.Jp0@usenet.ucs.indiana.edu>
Date: 4 Nov 92 15:44:15 GMT
Sender: kristoff@net.bio.net
Organization: Biology, Indiana University - Bloomington
Lines: 148
Approved: bionews-moderator@net.bio.net
Xref: biosci bionet.software:3567 bionet.announce:242


New Drosophila data search and retrieval thru Internet network
services are now available from the computer ftp.bio.indiana.edu.
These services are found using Internet Gopher or Wide Area Information
Service (WAIS). 


The Gopher services for Drosophila at ftp.bio.indiana.edu
look like this:


                    Root gopher server: ftp.bio.indiana.edu

      1.  About-IUBio-Gopher  [21Jun92, 3kb].
      2.  About-New-Features  [ 1Nov92, 3kb].
 -->  3.  Drosophila/
      4.  Genbank-Sequences/
      5.  IUBio-Software+Data/
            (more...)


                                  Drosophila

 -->  1.  About Drosophila Gopher  [23Feb92, 1kb].
      2.  Clone database search <?>
      3.  Cytological features search <?>
      4.  Drosophila Archive/
      5.  Drosophila Information Newsletter <?>
      6.  Drosophila Stocks at Bloomington, USA  <?>
      7.  Drosophila Stocks at Bowling Green, USA  <?>
      8.  Drosophila Stocks at Umea, Sweden <?>
      9.  Fly worker & GSA address search <?>
      10. Flybase/
      11. Flybase search  <?>
      12. Redbook/
      13. Redbook search <?>

All of the <?> services are WAIS/Gopher searches of fly data
files that reside in the Drosophila Archive:
   Clone database search == search clonelist.txt
   Cytological features search == search Amero.txt
   Drosophila Information Newsletter == search newsletter issues
   Drosophila Stocks ... == search stock lists
   Fly worker address search == search Haynie & GSA address files
   Flybase search == search Ashburner flybase files
   Redbook search == search complete Lindsley & Zimm Genome book

These search services are also available via WAIS client software.
The relevant WAIS source for IUBio archive is:
(:source 
   :version  3 
   :ip-address "129.79.224.25"
   :ip-name "ftp.bio.indiana.edu"
   :tcp-port 210
   :database-name "INFO"
   :cost 0.00 
   :cost-unit :free 
   :maintainer "archive@bio.indiana.edu"
   :description "
This WAIS service includes several indexed Biology information sources,
including Genbank nucleic acid gene sequence databank, Drosophila genetics
BioSci/Bionet network news, and others. 
")

And the fly wais databases are named:
   :database-name "fly-address"
   :database-name "fly-amero"   
   :database-name "fly-clones"
   :database-name "fly-din"
   :database-name "flybase"
   :database-name "flystock-bg"
   :database-name "flystock-bl"
   :database-name "flystock-um"
   :database-name "redbook"


As a reminder, client software for Macintosh, MS-Dos, Unix, VMS and
other computer systems are available for Internet Gopher via
anonymous ftp to boombox.micro.umn.edu, in /pub/gopher, and client
software for WAIS is available via ftp to ftp.think.com.   There
are also some of these available via ftp to ftp.bio.indiana.edu,
in /util/gopher and /util/wais directories.


I've modified the WAIS indexing and searching software in several
ways to make it more suitable for biology and genetic data searching.
These modifications include 
   a) use of symbols, so that queries like "In(4;5)red39" should
      work
   b) boolean 'and' and 'not' operators to limit a query results
   c) partial word searches, such as "hum*" matches human and hummingbird
   d) literal phrase searches, such finding "red rooster[45]" exactly
   e) output of data file headers (Gopher only so far).


The use of symbols is still somewhat problematic, since WAIS is based
on free text indexing, rather than on indexing of delimited fields
in databases, it needs to use some characters and symbols to delimit
words.  I've tried to find a distinction between symbols needed for genetic
"words" and symbols needed for distinguishing words (other than spaces),
but there is some overlap.  If you use the literal phrase search,
by enclosing a phrase with symbols in quote (') or double quote (")
marks, you may get better results.

For instance, in some of the fly data files, esp. redbook, "(" and ")" 
are used both as genetic symbols and as word delimiters.  Thus
searching for 
  Df(3)something
will generally parse into searching for the three words "Df"  "3" 
and "something", producing lots of matches.   While using a literal 
search,  
  'Df(3)something'
should limit the results to just that phrase.

There are other ways to better index genetic symbols, but they involve
more effort.  I'd like to get some feedback first on the usefullness
of this, from the general community of Internet-enabled fly
researchers.


The header file output adds a useful touch.  Here is one result
returned from a search of flybase for "ashburner":

This section is from the document '//Drosophila/Drosophila Archive/flybase/ABREFS.TEXT'.

gene-symbol         first-author           reference
------------        ----------------       -----------------------
Df(2L)ScoR+4                            Ashburner, Genetics 126:679
                                        McGill, Genetics 119:647
 

And a search for "red" produces this:
This section is from the document '//Drosophila/Drosophila Archive/flybase/LOCI.TEXT'.

gene-name-abbrev;  full-gene-name
    gene-map-position   cyto-map-position
        function
            nucleic-acid-databank-accession-number
                ditto-for-species-other-than-melanogaster
                    protein-database-accession-number
                        ditto-for-other-species
----------------------------------------------------------
red;    red
          3-53.6     88B1-88B2

-- 
Don Gilbert                                     gilbert@bio.indiana.edu
biocomputing office, biology dept., indiana univ., bloomington, in 47405

From owner-software@net.bio.net Wed Nov 04 22:00:00 1992
Path: biosci!uwm.edu!spool.mu.edu!sgiblab!pacbell.com!well!well.sf.ca.us!dove
From: dove@well.sf.ca.us (Rick Dove)
Newsgroups: bionet.software
Subject: Looking for movement tracking/analysis package
Summary: Need to track lip movements as words are spoken, point-wise
Message-ID: <dove.720933569@well.sf.ca.us>
Date: 5 Nov 92 03:19:29 GMT
Sender: news@well.sf.ca.us
Organization: Whole Earth 'Lectronic Link
Lines: 13


I need to analyze how lips move while speaking english words so I can use
this mechanical movement info to drive animated lips. Actually, I will also
be monitoring key muscle groups in the face as well probably.

Is there any software available for the PC that will allow me to analyze
video input and generate point displcaement over time? It would be ok to put
"marks" on the human face before video input. I dont have access to any
fancy pens or tablets - but it would be ok to "mark" a screen image with the
mouse and have the software then track that point(s) as it moves through
frames. Maybe you have another suggestion?

Please forward any helpful suggestions to me at dove@well.sf.ca.us

From owner-software@net.bio.net Wed Nov 04 22:00:00 1992
Path: biosci!daresbury!news
From: robertson@mpib-tuebingen.mpg.dbp.de (BRAIN ROBERTSON)
Newsgroups: bionet.software
Subject: Mac front-end for VAX GCG
Message-ID: <1992Nov5.153519.15673@gserv1.dl.ac.uk>
Date: 5 Nov 92 15:34:33 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 30
Content-Identifier: 12
Original-To: bio-soft@uk.ac.daresbury
Conversion: Prohibited


Last week I posted a question concerning a Mac front end for the GCG programs
running on a VAX that I has read about. Thanks to all those who troubled to
reply. Here is a quick summary of the results:

1. Don Gilbert wrote a hypercard stack to acts as an interface, called 
HyperGCG.It is available by ftp from two places that I know of:
	ftp.bio.indiana.edu in molbio/mac hypergcg.hqx
	sunbcd.weizmann.ac.il in pub/software/mac/

However, Don Gilbert writes "I do not support this software.......nor do I 
recommend it except to those with some knowledge of hypercard programming and 
the time to mess with it." Well, I think that it plain enough!

2. Will Gilbert used MacWorkstation as a front end to VMS and GCG, and made a 
lot of progress, but abandoned it when good packages became available on the
Mac, and because MWS became too expensive. None of what he wrote is available.

Therefore it looks pretty bad if you are trying to introdue PC users to VMS and
GCG. However, I have heard that a version of GCG running under Xwindows should
be available sometime in 1993/94. This would allow users running MacX etc to
access the system.

Meantime hang on in there folks!

	Brian Robertson
	MPI fuer Biologie
	D74 Tuebingen
	Germany
	e-mail: robertson@mpib-tuebingen.mpg.dbp.de

From owner-software@net.bio.net Wed Nov 04 22:00:00 1992
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!saimiri.primate.wisc.edu!ames!decwrl!concert!uvaarpa!gems.vcu.edu!agnew
From: agnew@gems.vcu.edu
Newsgroups: bionet.software
Subject: Need help on analyzing ECG's
Message-ID: <1992Nov5.150107.160@gems.vcu.edu>
Date: 5 Nov 92 19:01:07 GMT
Organization: Medical College of Virginia
Lines: 12

Dear netpeople,
  I'm in search of software and or source code to analyze human ECG/EKG
heart traces...  Please reply to this net address.  Many Thanks!!!
Any leads at all will be much appreciated.

Jim


         /^^^\   \ /   Jim Agnew         | AGNEW@RUBY.VCU.EDU  (Internet)
        /      >  ||   Neurosurgery,     | AGNEW@VCUVAX        (Bitnet)
   /\_/     '   \  /   MCV-VCU           | This disc will self destruct in
 /________________>    Richmond, VA, USA | five seconds.  Good luck, Jim..."

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!agate!ames!saimiri.primate.wisc.edu!zaphod.mps.ohio-state.edu!sdd.hp.com!news.cs.indiana.edu!nstn.ns.ca!ac.dal.ca!isbruck
From: isbruck@ac.dal.ca
Newsgroups: bionet.software
Subject: Data Entry into LIGAND
Message-ID: <1992Nov5.214137.8652@ac.dal.ca>
Date: 6 Nov 92 01:41:37 GMT
Organization: Dalhousie University, Halifax, Nova Scotia, Canada
Lines: 14




When using LIGAND, is it possible to bypass the SCAPRE program and
use SCAFIT for data that is already in moles/L?  How do I do this?


Thanks,



Richard Isbrucker                      ISBRUCK@AC.DAL.CA
Dalhousie University
Department of Pharmacology

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!swrinde!zaphod.mps.ohio-state.edu!news.acns.nwu.edu!network.ucsd.edu!sluggo!gribskov
From: gribskov@sdsc.edu (Michael Gribskov)
Newsgroups: bionet.software
Subject: seqanalref->EndNote
Message-ID: <1dbvd5INNtv@network.ucsd.edu>
Date: 5 Nov 92 20:15:33 GMT
Reply-To: gribskov@sdsc.edu
Organization: San Diego Supercomputer Center @UCSD.
Lines: 11
NNTP-Posting-Host: sluggo.sdsc.edu

We have recently acquired the literature reference manager EndNote.  I am interested in reading in some or all of the references in seqanalref, but need a filter to convert the format to something EndNote can read.  If anyone has done this and can supply
me with code for VMS,Unix,or Mac I would be very grateful.

Alternatively, since EndNote is supposed to be able to read ProCite format, perhaps someone could provide me with seqanalref in ProCite format.  Erik Sonnhammer at EMBL has apperently written a PC program to convert seqanalref to ProCite format.  Unfort-
unately, I do not have access to any kind of IBM type PC.  Is anyone that has done this conversion willing to supply me with the converted file?

Thanks for the help

Michael Gribskov
San Diego Supercomputer Center
gribskov@sdsc.edu

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!swrinde!emory!wupost!zaphod.mps.ohio-state.edu!saimiri.primate.wisc.edu!ames!agate!doc.ic.ac.uk!daresbury!bioftp.unibas.ch!comp.bioz.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: Mac front-end for VAX GCG
Message-ID: <1992Nov6.063754.17892@comp.bioz.unibas.ch>
Date: 6 Nov 92 06:37:54 GMT
References: <1992Nov5.153519.15673@gserv1.dl.ac.uk>
Sender: usenet@comp.bioz.unibas.ch (NEWS transaction account)
Reply-To: doelz@urz.unibas.ch
Distribution: bionet
Organization: EMBnet Switzerland [BASEL]
Lines: 28
Nntp-Posting-Host: biox.embnet.unibas.ch

In article <1992Nov5.153519.15673@gserv1.dl.ac.uk>, robertson@mpib-tuebingen.mpg.dbp.de (BRAIN ROBERTSON) writes:
|> 
|> Therefore it looks pretty bad if you are trying to introdue PC users to VMS and
|> GCG. However, I have heard that a version of GCG running under Xwindows should
|> be available sometime in 1993/94. This would allow users running MacX etc to
|> access the system.

I (hopefully) will be able to get the QUERY system for public release quite 
soon. This is like the GCGNAV on UNIX but also runs on VMS. The pain with 
all these menu systems/front ends is that you need to maintain the menu 
definition langue to be quite simple. Thus, comfortable environments will 
cause a lot of overhead in maintenance (and , presumably, speed.). Second, 
who would like to start fasta with 20 clicks rather than type fasta and that's 
it? Last, don't overestimate the technology at the individual sites. Despite 
the growing 'high end' user basis, we still have the majority of our users
on serial lines. I made some attempts to run SLIP along these lines. Not 
surprisingly, X performance is moderate at best. 


-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |
|   Klingelbergstrasse 70          | FAX     x41 61 261- 6760 or 267- 2078     
|     CH 4056 Basel                | TEL     x41 61 267- 2076 or 2247    |   
+------------- bioftp.unibas.ch is the SWISS EMBnet node ----------------+
               -----------------------------------------

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!SALK-SC2.SDSC.EDU!mangalam
From: mangalam@SALK-SC2.SDSC.EDU
Newsgroups: bionet.software
Subject: Re:
Message-ID: <9211061822.AA17484@net.bio.net>
Date: 6 Nov 92 18:22:16 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 50

Jim Cassatt writes:

>Got a couple of questions for those who run gopher.
>
>First - We are running tn3270 on a 3com network.  The gopher
>client cannot access the TCP stack even though the bat files have
>been properly constructed.  Our LAN manager says that the trouble
>is the 3com network.  Is this correct?

Ack!  Sorry, can't help you there - while you didn't want to hear this,
this is one very real reason that Macs are much easier to interface with
TCP/IP - one relatively solid, reliable interface (MacTCP).  Drop the file
into your system folder and everything (gopher, eudora, WAIStation, Fetch,
Versaterm, etc) works 1st time every time (almost... 8-)

>
>Second - As an alternative I am using the gopher client that
>resides on the NIH computer.  Recently the PDB announced the
>establishment of a gopher that I would like to access.  Going
>through the available menus it is not apparent to me how to
>access a gopher hole that is not listed on the menus.  Any
>advice?

   Yes, just initaiate a new gopher wiith the following data:

Type = 1 (so that the icon is a folder)
Title = PDB/Brookhaven Data	(or something more personal)
Address =	pdb.pdb.bnl.gov (domain name of the server)
port =	70 (standard gopher port)

This is done (if using Don Gilbert's Gopher App) by selecting the 'Internet
| New Gopher Link' menu items and filling out the blanks appropriately.

   Or if using the PC version (PC Gopher II), you can use the Options |
Configure menu selection and fill out the blanks as above.

   However, the "New Gopher" selection (Alt+G) does not work as appears to
be advertised - all it does is bring up the initial screen again.  

A note to the authors is warranted.

Cheers,
Harry

Harry Mangalam                                   Vox:(619) 453-4100, x250
Dept of Biocomputing                                   Fax:(619) 552-1546
The Salk Institute                             mangalam@salk-sc2.sdsc.edu
10010 N Torrey Pines Rd                        mangalam@salk-sgi.sdsc.edu
La Jolla CA 92037                                    mangalam@salk.bitnet


From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!CU.NIH.GOV!CZJ
From: CZJ@CU.NIH.GOV
Newsgroups: bionet.software
Subject: (none)
Message-ID: <9211061716.AA12536@net.bio.net>
Date: 6 Nov 92 17:14:01 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 16

Got a couple of questions for those who run gopher.

First - We are running tn3270 on a 3com network.  The gopher
client cannot access the TCP stack even though the bat files have
been properly constructed.  Our LAN manager says that the trouble
is the 3com network.  Is this correct?

Second - As an alternative I am using the gopher client that
resides on the NIH computer.  Recently the PDB announced the
establishment of a gopher that I would like to access.  Going
through the available menus it is not apparent to me how to
access a gopher hole that is not listed on the menus.  Any
advice?

Jim Cassatt


From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!daresbury!news
From: PARSONS_A@snd01.pcr.co.uk
Newsgroups: bionet.software
Subject: Weizmann Institute EMBNet node
Message-ID: <1992Nov6.105425.4894@gserv1.dl.ac.uk>
Date: 6 Nov 92 10:13:46 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 20
Original-To: BIO-SOFT <BIO-SOFT@UK.AC.DARESBURY>

Neteers,

Am I right in thinking there is a sequence retrieval service in Israel that
is available.  I dont get a peep out of the NCBI and EMBL is a bit slow
in turnaround.  Any other pointers to other (faster but equally current) nodes
would be much appreciated.

Ta,

Tony P.

 +----------------------------------------------------------------------------+
 | Dr.Tony Parsons,			VOX   : + 44 304 616871	              |
 | IT Department,			FAX   : + 44 304 616670               |
 | Pfizer Central Research,				 		      |
 | Ramsgate Road,  +----------------------   e-mail   ------------------------+
 | Sandwich,       |JANET      : parsons_a@uk.co.pcr.snd01                    |
 | KENT	           |Internet   : parsons_a@snd01.pcr.co.uk	       	      |
 | CT13 9NJ UK	   |Compuserve : 100064,765    PSImail:234216700127.parsons_a |
 +-----------------+----------------------------------------------------------+

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!daresbury!embnet.se!corax.udac.uu.se!sunic!lth.se!pollux.lu.se!nuntius
From: Bo.Servenius@wblab.lu.se (Bo Servenius)
Newsgroups: bionet.software
Subject: GratefulMed over TCP/IP???
Message-ID: <1992Nov6.101626.5172@pollux.lu.se>
Date: 6 Nov 92 10:16:26 GMT
Sender: news@pollux.lu.se (Owner of news files)
Organization: Lund University, SWEDEN
Lines: 12
Nntp-Posting-Host: macservenius.wblab.lu.se
X-Useragent: Nuntius v1.1

Dear Netters:

Have started to look into GratefulMed for searching Medline.
However I have a problem. The Swedish version of it can only handle
communication over telephone modems. And that is costly and
inconvinient
as all my communications nowadays are over TCP/IP. Does anyone know
if there is a version that is possible to run over TCP/IP????

yours

BOSSE

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!daresbury!bioftp.unibas.ch!biox!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: Weizmann Institute EMBNet node
Message-ID: <doelz.721080887@biox>
Date: 6 Nov 92 20:14:47 GMT
References: <1992Nov6.105425.4894@gserv1.dl.ac.uk>
Distribution: bionet
Organization: EMBnet Switzerland [Basel]
Lines: 20

PARSONS_A@snd01.pcr.co.uk writes:


>Am I right in thinking there is a sequence retrieval service in Israel that
>is available.  I dont get a peep out of the NCBI and EMBL is a bit slow
>in turnaround.  Any other pointers to other (faster but equally current) nodes
>would be much appreciated.

If you mean internet-access GOPHER, there are gopher servers in Indiana, 
Houston and Basel serving you Genbank, PIR , EMBL and Swissprot respectively
in a (crude) keyword search. Was that the meaning of "retrieval service"? 

Regards 
Reinhard 

-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!cs.utexas.edu!uunet!nih-csl.dcrt.nih.gov!donp
From: donp@niaid.nih.gov (Don Preuss)
Newsgroups: bionet.software
Subject: Re: GratefulMed over TCP/IP???
Message-ID: <1992Nov6.192056.23513@alw.nih.gov>
Date: 6 Nov 92 19:20:56 GMT
References: <1992Nov6.101626.5172@pollux.lu.se>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Organization: National Institutes of Health
Lines: 23

Bo.Servenius@wblab.lu.se (Bo Servenius) writes:


Yes. Grateful Med 6.0 can work over tcpip. You can use either a version
that works with Wollongong, or a version that works with a packet
driver. (Uses ncsa for the engine.). I think it it somewhere around
$25 to order it with hard copy, but it is all ftp'able from the National
Library of Medicine.

donp
donp@niaid.nih.gov
>Dear Netters:

>Have started to look into GratefulMed for searching Medline.
>However I have a problem. The Swedish version of it can only handle
>communication over telephone modems. And that is costly and
>inconvinient
>as all my communications nowadays are over TCP/IP. Does anyone know
>if there is a version that is possible to run over TCP/IP????

>yours

>BOSSE

From owner-software@net.bio.net Thu Nov 05 22:00:00 1992
Path: biosci!daresbury!bioftp.unibas.ch!biox!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: (none)
Message-ID: <doelz.721081047@biox>
Date: 6 Nov 92 20:17:27 GMT
References: <9211061716.AA12536@net.bio.net>
Distribution: bionet
Organization: EMBnet Switzerland [Basel]
Lines: 26

CZJ@CU.NIH.GOV writes:

>Second - As an alternative I am using the gopher client that
>resides on the NIH computer.  Recently the PDB announced the
>establishment of a gopher that I would like to access.  Going
>through the available menus it is not apparent to me how to
>access a gopher hole that is not listed on the menus.  Any
>advice?

 In the Bioftp gopher in Basel the PDB gopher has a link in 
EMBnet Resource Basel / Databases. It won't hel you much, though, if the
client at NIH doesn't get you files saved or mailed to you. Very soon, 
Europe will have subject-oriented gopher trees so that there should be 
a central register for biology applications available. 


Maybe this helps 

Regards 
Reinhard 

-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |

From owner-software@net.bio.net Fri Nov 06 22:00:00 1992
Path: biosci!agate!spool.mu.edu!uunet!decwrl!access.usask.ca!sklib.usask.ca!scott
From: scott@sklib.usask.ca
Newsgroups: bionet.software
Subject: RE: (none)
Message-ID: <7NOV92.15270067@sklib.usask.ca>
Date: 7 Nov 92 15:27:00 GMT
References: <9211061716.AA12536@net.bio.net>
Sender: news@access.usask.ca (USENET News System)
Organization: University of Saskatchewan
Lines: 25
Nntp-Posting-Host: sklib.usask.ca

In a previous article, CZJ@CU.NIH.GOV wrote:

>Second - As an alternative I am using the gopher client that
>resides on the NIH computer.  Recently the PDB announced the
>establishment of a gopher that I would like to access.  Going
>through the available menus it is not apparent to me how to
>access a gopher hole that is not listed on the menus.  Any
>advice?

One thing you can try is to connect to the main gopher at UMN via Telnet 
to consultant.micro.umn.edu, login gopher.
Go to Other Gophers/North America/Brookhaven National Laboratory.

Then pick the link to the NIH Gopher Site.
This is defined as:

Name=NIH Gopher site
Type=1
Port=70
Path=1/
Host=helix.nih.gov


Peter Scott - Manager, Small Systems, University of Saskatchewan Libraries
                        <scott@sklib.usask.ca>

From owner-software@net.bio.net Sat Nov 07 22:00:00 1992
Path: biosci!agate!spool.mu.edu!uunet!pipex!pavo.csi.cam.ac.uk!mbfs.bio.cam.ac.uk!seb1005
From: seb1005@mbfs.bio.cam.ac.uk (Steven Brenner)
Newsgroups: bionet.software
Subject: Unix Bibliography Programs?
Message-ID: <1992Nov8.002323.10817@infodev.cam.ac.uk>
Date: 8 Nov 92 00:23:23 GMT
Sender: news@infodev.cam.ac.uk (USENET news)
Organization: U. of Cambridge, England
Lines: 13
Nntp-Posting-Host: mbfs.bio.cam.ac.uk

I'm looking to organize the articles I've read on the computer rather than
keeping bits and pieces of references all over the place.

I've seen in the bionet archives articles about bibliography managers for the Mac
and PC, but haven't seen much discussion for Unix systems.

Can people please suggest good bibliography/reference programs?  I'll post a
summary to to the net.

Thanks very much

Steven Brenner
seb1005@mbfs.bio.cam.ac.uk

From owner-software@net.bio.net Sun Nov 08 22:00:00 1992
Path: biosci!agate!usenet.ins.cwru.edu!magnus.acs.ohio-state.edu!zaphod.mps.ohio-state.edu!caen!uunet!mcsun!Germany.EU.net!uniol!Jens.Burkert
From: Jens.Burkert@arbi.informatik.uni-oldenburg.de (Jens Burkert)
Newsgroups: bionet.software
Subject: wanted: neural spike trains
Summary: wanted neural spike trains
Keywords: neural spike
Message-ID: <1992Nov9.133712.16135@arbi.Informatik.Uni-Oldenburg.DE>
Date: 9 Nov 92 13:35:36 GMT
Sender: news@arbi.Informatik.Uni-Oldenburg.DE
Organization: University of Oldenburg, Germany
Lines: 29

Hello!

I'm looking for spike train data produced from real neurons.

It is for the analyse of stochastic point processe described by Perkel,
Gerstein and Moor (1967) and crosscorrellation analyse.

Spike trains from two interacting (inhibitory or excitatory)
pacemaker (or other) neurons would be very welcome.

The organisation of the data should be in Intervals
e.g.
|   |   |    |   |        <-  neuronal spike train
 10  10  15   10      ms
or 
|   |   |    |   |
0   10  20   35  45  ms

also floating point.

Thank you
Jens Burkert


-- 
Jens Burkert (jens)     *    Abteilung Prozessinformatik
Universitaet Oldenburg   *   DW-2900 Oldenburg  (FRG)
EARN:  Jens.Burkert%arbi.informatik.uni-oldenburg.de@DOLUNI1
ISO:  Jens.Burkert@arbi.informatik.uni-oldenburg.de

From owner-software@net.bio.net Sun Nov 08 22:00:00 1992
Path: biosci!BRUFSC.bitnet!EEL3FPS
From: EEL3FPS@BRUFSC.bitnet (Fernando Passold)
Newsgroups: bionet.software
Subject: Help
Message-ID: <9211091929.AA08596@net.bio.net>
Date: 9 Nov 92 19:29:45 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Organization: Universidade Federal de Santa Catarina/BRASIL
Lines: 54

Dear Sir.:                                       Fl 11/09/92
(List Moderator)

    I would like to know the  intend of this  list  and if I
could obtain some replies.

    I am a researcher tacking part of Biomedical Engineering
Group Laboratory of Electrical Engineering Department at the
Federal University of  Santa  Catarina. We  develop   little
biomedical equipments  and  Expest Systems - such a Hospital
Infection Control Aid and a  Hybrid  System  (rule-based and
neural  network  based)  for  Proposal  and   Evaluation  of
Anesthesian Plan.

    I am a master degree student, now, grapple in develop  a
Expert Network  (also  called,  hybrid  system:  those  whom
combine  neural  networks   with   rule-based  methods)  for
Planning and Evaluation of  Plans of  Anesthesia, continuing
a  PHD  thesis,  for  Critical  Patients  (their  who   need
critical  cares) or Problem   Patients (exceptional cases of
patientes whom evaluate to critical patients).  I  have some
troubles choosing the  most  suitable  approach  to  develop
this system. I do not know if neural  networks could  be the
key to solve the main part of the problem,  because  we  are
dealing with  exceptions  that  probably could  best  solved
throught a rule-based method.  At  lately, there are  a  few
shells systems   applying  object-orienthed  technics   with
rule-based    or  frames  methods  such  the  new   Kappa PC
Application Development Systems   for   Windows environment,
from   IntellCorp.   Inc..     So,  I   am   interested   in
implementations   of  hybrid systems   using object-oriented
programming. Maybe, there will   be a  way to  link   neural
networks simulators   using   object-oriented   approach  to
another heuristical   languages such as Turbo-Prolog object-
oriented.

    I would be glad if someone  could make  a comment  about
it, as well as indicate if there exists a _similar research_.

    Please, reply directly to me  as I am not   subcribed to
this list.

    Thanks a lot respect to this matter,

best regards,

Fernando Passold
Biomedical Engineering Group Lab.
UFSC/BRAZIL
E-mail: ee3fps@brufsc.bitnet


P.S.: I am interested in subcribing in your list if not a
      large amount of material is normaly posted to it.

From owner-software@net.bio.net Sun Nov 08 22:00:00 1992
Path: biosci!agate!spool.mu.edu!uunet!mcsun!sunic!lth.se!pollux.lu.se!nuntius
From: Bo.Servenius@wblab.lu.se (Bo Servenius)
Newsgroups: bionet.software
Subject: GratefulMed over tcp/ip???? for Mac!!!
Message-ID: <1992Nov8.225129.15997@pollux.lu.se>
Date: 8 Nov 92 22:51:29 GMT
Sender: news@pollux.lu.se (Owner of news files)
Organization: Lund University, SWEDEN
Lines: 13
Nntp-Posting-Host: macservenius.wblab.lu.se
X-Useragent: Nuntius v1.1

Dear Netters:

Thanks for your comments about gm6.0. But which is the tcp/ip adress
where I can find it for free FTP????

BTW gm6.0 is for PC isn't it??? Is there a tcp/ip version for Macs
as well??


yours


BOSSE

From owner-software@net.bio.net Sun Nov 08 22:00:00 1992
Path: biosci!bcm!lib!dfenyes
From: dfenyes@thesis1.med.uth.tmc.edu (David Fenyes,ms89,,7901935)
Newsgroups: bionet.software
Subject: Looking for *nix protein/gene software
Keywords: protein dna rna analysis software
Message-ID: <7790@lib.tmc.edu>
Date: 9 Nov 92 22:00:06 GMT
Sender: usenet@lib.tmc.edu
Organization: University of Texas Medical School at Houston
Lines: 19
Nntp-Posting-Host: thesis1.med.uth.tmc.edu

Hello *,

I'm a grad student studying the Alzheimer's beta-amyloid precursor
protein at U.T Houston, and am looking for a suite of DOS or unix-based
protein/gene analysis tools, particularly one with the capability
to read the formats used my major gene/protein databases.

I'm aware of DOS-based suites such as PC-Gene (tm), but in general
the astronomical pricing and awkward usage makes these less than
ideal.  

I'd be happy to post any information I receive.

Thanks for any info,

David
--
David Fenyes                                 dfenyes@thesis1.med.uth.tmc.edu
University of Texas Medical School           Houston, Texas

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!daresbury!embnet.se!bio.embnet.se!sunic!lth.se!pollux.lu.se!nuntius
From: Bo.Servenius@wblab.lu.se (Bo Servenius)
Newsgroups: bionet.software
Subject: The program Amplify for PCR design - where can I find it???
Message-ID: <1992Nov10.012249.1058@pollux.lu.se>
Date: 10 Nov 92 01:22:49 GMT
Sender: news@pollux.lu.se (Owner of news files)
Organization: Lund University, SWEDEN
Lines: 8
Nntp-Posting-Host: macservenius.wblab.lu.se
X-Useragent: Nuntius v1.1

Dear Netters:

Have heard about a program Amplify for designing of PCR primers.
Is it a freeware/shareware and if so where can I find it for FTP???

yours

BOSSE

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!caen!batcomputer!reed!bowman
From: bowman@reed.edu (Eric Bowman (bobo))
Newsgroups: bionet.software
Subject: InPlot for Mac?
Message-ID: <1992Nov10.000502.20308@reed.edu>
Date: 10 Nov 92 00:05:02 GMT
Organization: Reed College, Portland, OR
Lines: 12

My apologies if you see this twice, we're having news problems...

We got an add for some PC software, InPlot, which looks like exactly what
we want for Macs.  Specifically, very general data plotting capabilities
(scatter, line, bar, error bars, etc.), plus non-linear regression, plus
Scatchard plots.

Does such a product exist for Macintosh?

Thanks,
Eric Bowman
bowman@reed.edu

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!uwm.edu!caen!sdd.hp.com!elroy.jpl.nasa.gov!swrinde!network.ucsd.edu!riscsm!collet
From: collet@scripps.edu (Thomas Collet)
Newsgroups: comp.sys.mac.wanted,bionet.software
Subject: MolBio Software for sale in Germany
Message-ID: <1992Nov9.223937.4699@riscsm.scripps.edu>
Date: 9 Nov 92 22:39:37 GMT
Sender: usenet@riscsm.scripps.edu
Organization: The Scripps Research Institute, La Jolla, California, USA
Lines: 8
Xref: biosci comp.sys.mac.wanted:1482 bionet.software:3587

For sale in Germany: Molecular Biology software for the Macintosh

PlasmidArtist 1.2 newest version !!!
	Draw publication-quality plasmid maps and print them or export the 		to page layout programs.

AssemblyLign: alignment of DNA sequences in conjuntion with or without 	MacVector.

As I now live in Germany and have only sporadic email access, I would very much prefer a phone call to 0211 / 31 72 19. I will then call back serious candidates.

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!agate!spool.mu.edu!sdd.hp.com!ux1.cso.uiuc.edu!news.cso.uiuc.edu!phylo!scott
From: scott@phylo.life.uiuc.edu (Snooky Fudge)
Newsgroups: bionet.software
Subject: Re: The program Amplify for PCR design - where can I find it???
Message-ID: <scott.721365990@phylo>
Date: 10 Nov 92 03:26:30 GMT
References: <1992Nov10.012249.1058@pollux.lu.se>
Sender: usenet@news.cso.uiuc.edu (Net Noise owner)
Organization: University of Illinois at Urbana
Lines: 9

anonymous ftp to sumex-aim.stanford.edu, among billions of others.

--
Coffee Facts from Dr. Science:
1) You can never brew coffee too strong.
2) You can never drink too much coffee.
3) Coffee does not make you nervous.  Your own inadequacies do that.
   Coffee merely increases your perception of your own inadequacies.
4) Tea is to coffee as ginger ale is to Scotch.

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!CSC.FI!Rob.Harper
From: Rob.Harper@CSC.FI (Rob Harper)
Newsgroups: bionet.software
Subject: Recent msdos uploads to SIMTEL20 (25-Oct - 9-Nov 1992)
Message-ID: <199211101018.AA01290@csc.fi>
Date: 10 Nov 92 10:18:36 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 379


The following files have been recently uploaded to WSMR-SIMTEL20.ARMY.MIL
(between 25-Oct-92 and 9-Nov-92):

NOTE: Type B is Binary; Type A is ASCII

 Filename   Type Length   Date    Description
==============================================
Directory PD1:<MSDOS.4DOS>
4D401D.ZIP    B   29134  921031  4DOS/4OS2 patch files to update to revision d
4DATEF.ZIP    B    2372  921026  .BTM functions: Day-of-Week, Number-of-Week
4DMAN10B.ZIP  B    2915  921026  Unix-like MAN, searches docs for cmds, .BTM
4DOS401D.ZIP  B  257581  921031  4DOS401B COMMAND.COM replacement, manual, 1/2
4DOS401P.ZIP  B  288840  921031  4DOS401B COMMAND.COM replacement, exe/pgms,2/2
4DOS401U.ZIP  B  247377  921031  4DOS401B update for registered 4DOS 4.0 users
4DOSNG.ZIP    B   98951  921031  Norton Guides Database for 4-DOS Command.Com
4DPATH.ZIP    B    1467  921026  Add/remove path(s) to/from %PATH (.BTM)
4ERROR.ZIP    B    2511  921026  Show description for given DOS error, .BTM
4FC12.ZIP     B   25198  921031  4Comment: Extracts file descriptions from 4DOS
4MENU10B.ZIP  B    5374  921026  Desktop MENU interface for 4dos (.BMT)
4RANDOM.ZIP   B    2626  921026  Pseudo-random generator for 4dos (.BTM)
4WHTS10B.ZIP  B    1952  921026  WHATIS, 'what-this-cmd-stands-for'-cmd, .BTM
EZ-BTM04.ZIP  B   49792  921026  4DOS BTM files: loaders/regular/libraries/help
MAV120.ZIP    B    3763  921029  4DOS BTM file: Mally's Archive Viewer

Directory PD1:<MSDOS.ARC-LBR>
AM83.ZIP      B  218768  921108  ArcMaster front-end/convrt for ARC/ARJ/LZH/ZIP
FV141.ZIP     B    8859  921108  View dirs of ARC/DWC/LBR/LZH/PAK/ZIP/ZOO/SFXs
SHEZ82.ZIP    B  207888  921031  Shell for archive manipulation, w/virus check
SHEZT.ZIP     B   35928  921031  Online tutorial for first time SHEZ users

Directory PD1:<MSDOS.AUTOCAD>
NUMCMD.ZIP    B   86656  921027  Number-Pad based Interface for AutoCAD R12/386

Directory PD1:<MSDOS.BASIC>
BASWIZ18.ZIP  B  303084  921107  ASM/BASIC lib routines for QBasic/BASCOM/PDS
BPP10.ZIP     B   52729  921107  Preprocessor for QBASIC/QuickBasic/BASCOM/PDS
BWB110E.ZIP   B   81068  921029  Bywater BASIC Interpreter 1.10, EXE and doc
BWB110S.ZIP   B  116429  921029  Bywater BASIC Interpreter 1.10, C source code
LIBWIZ13.ZIP  B   82579  921107  Hanlin's Library Wizard BASIC library manager
PBCLON20.ZIP  B  399272  921107  PBClone: ASM/BASIC lib. Replaces ProBas/ADVBAS

Directory PD1:<MSDOS.BATUTL>
TSBAT39.ZIP   B   93500  921026  Collection of useful batch files by Timo Salmi

Directory PD1:<MSDOS.BBS>
BDOC_256.ZIP  B  112733  921026  Binkleyterm mail/term pgm docs v2.56 Beta
BNKB256.ZIP   B  181752  921026  Binkleyterm 2.56 Beta executables & update doc
NLFE10.ZIP    B   71453  921106  NLFE v1.0: Frontend PCBoard for Internet/UUCP

Directory PD1:<MSDOS.BBSLISTS>
ASPBBS24.ZIP  B   59127  921108  Listing of all ASP approved BBSs, as of Oct 92
BBS1092C.ZIP  B   95990  921026  'THELIST' national BBS list for October 1992

Directory PD1:<MSDOS.C>
QUIKC21.ZIP   B   77016  921026  Quick screen utilities v2.1 for Turbo C & MS C

Directory PD1:<MSDOS.CALCULATOR>
UCALC12.ZIP   B   53551  921027  Scientific expr. evaluator with many features

Directory PD1:<MSDOS.CATALOG>
CDISK632.ZIP  B  258866  921026  Disk catalog system also does ARC/PAK/ZIP/LBR

Directory PD1:<MSDOS.DATABASE>
FE51-A.ZIP    B  308483  921026  File Express v5.10 database system, 1 of 3
FE51-B.ZIP    B  353036  921026  File Express v5.10 database system, 2 of 3
FE51-C.ZIP    B  305862  921026  File Express v5.10 database system, 3 of 3
GC11.ZIP      B   60464  921107  Graphical employee scheduling program
INV10.ZIP     B  179672  921027  Home inventory and moving management program
MM-701.ZIP    B  204416  921026  MealMaster database program for recipes, v7.01

Directory PD1:<MSDOS.DESQVIEW>
DVCPY200.ZIP  B  113239  921026  DESQview-aware copy util, works in Win3.x too

Directory PD1:<MSDOS.DIRUTL>
CCD100.ZIP    B   43406  921106  Quickly change directories (for NT and DOS)

Directory PD1:<MSDOS.DJGPP>
AEASY101.ZIP  B   72300  921102  ASYNC support for djgpp
AECUR101.ZIP  B  133335  921102  Curses for djgpp
AETSK101.ZIP  B   88004  921102  Full pseudo-tasking support for djgpp
AEWIN101.ZIP  B  114601  921102  Text windows for djgpp
CBGRD102.ZIP  B  303098  921102  GRX library, documentation
CBGRF102.ZIP  B  879369  921102  GRX library, fonts
CBGRX102.ZIP  B  842221  921102  GRX library, libs and includes
DJBSN116.ZIP  B  164589  921102  GNU bison-1.16 (djgpp)
DJDEV109.ZIP  B  796370  921102  Minimum development environment (djgpp)
DJDOC109.ZIP  B  103508  921102  All documentation for djgpp 1.09
DJEMU109.ZIP  B   78798  921102  EMU387 sources and executable (djgpp)
DJFLX237.ZIP  B  110526  921102  GNU flex-2.3.7 (djgpp)
DJG16222.ZIP  B   96126  921102  Real-mode gcc.exe
DJGAS138.ZIP  B   70425  921102  GNU gas-1.38.1 (djgpp)
DJGCC222.ZIP  B  856115  921102  GNU gcc-2.2.2, no cc1plus or cc1obj
DJGPO222.ZIP  B  977668  921102  GNU gcc-2.2.2 cc1plus and cc1obj
DJLGR109.ZIP  B   84001  921102  256-color graphics library (djgpp)
DJLSR109.ZIP  B  499781  921102  Sources for all libraries (djgpp)
DJPRF109.ZIP  B  274976  921102  Libraries and executables to use profiling
DJSRC109.ZIP  B  137481  921102  Sources for go32-utils-GNU-gr-drivers
DJSUP109.ZIP  B   26271  921102  readme, merge, split, manifest, Index, (djgpp)
QDDVX101.ZIP  B  975455  921102  Quarterdeck DESQview/X libraries for djgpp
SRBNU100.ZIP  B  219844  921102  djgpp source for binutils
SRBSN116.ZIP  B  281449  921102  djgpp sources for bison
SRDIF115.ZIP  B  123659  921102  djgpp sources for diff
SRFLX237.ZIP  B  177739  921102  djgpp sources for flex
SRGAS138.ZIP  B  369716  921102  djgpp sources for gas

Directory PD1:<MSDOS.DSKUTL>
CNFMT108.ZIP  B   44469  921026  Background floppy disk formatter by SYDEX
DOG320.ZIP    B   54611  921026  Disk OrGanizer: Disk defragmenter DOS5-compat.
FFIT161.ZIP   B   42287  921108  Copies files to disks optimally (knapsack)
HDTS535A.ZIP  B  139775  921026  Comprehensive HD test with support for DOS 5.0

Directory PD1:<MSDOS.EDITOR>
CEDIT30.ZIP   B  427997  921105  Mouse-based Chinese word processor (EGA/VGA)
TDE21.ZIP     B  339356  921102  PD multi-window/file text editor w/C & asm src
TRIVED07.ZIP  B   11593  921106  FOSSIL/console vi-like editor for BBS use
VDE164C.ZIP   B  149888  921031  Meyer's small, fast, WordStar-like text editor
VDE164CS.ZIP  B   17430  921031  Screen writers macros for VDE text editor
XVIDOC.ZIP    B   73662  921106  Xvi text editor - Documentation, 1 of 3
XVIEXE.ZIP    B   66835  921106  Xvi text editor - MS-DOS executable, 2 of 3
XVISRC.ZIP    B  261228  921106  Xvi text editor - Source code, 3 of 3

Directory PD1:<MSDOS.EDUCATION>
AALPHA.ZIP    B  485008  921026  Animated Alphabet for pre-school to 1st grader
AMATH1.ZIP    B  364071  921026  Animated Math: counting/addition/subtraction
AMEM10.ZIP    B  254102  921026  Animated Memory Game: aids kids' memory skills
ANIMSHAP.ZIP  B  294552  921026  Animated Shapes: shape & color identification

Directory PD1:<MSDOS.EMULATORS>
MYZ80103.ZIP  B   76581  921106  Simeon Cran's Z80 CP/M and Z-System emulator

Directory PD1:<MSDOS.FILEDOCS>
SIM9210.IDX   A   24657  921103  Comma-delimited list of October 1992 uploads
SIMAIL50.ZIP  B    9463  921103  Converts output of SIMTEL35 & SIMTEL22 to mail
SIMIBM.ZIP    B  275659  921110  Comma-delim list of all MSDOS files w/descrip.
SIMLIST.ZIP   B  269582  921110  Text format list of all MSDOS files w/descrip.
UPLOADS.OCT   A   23615  921103  List of uploads to SIMTEL20 for October 1992

Directory PD1:<MSDOS.FILUTL>
NCDC151.ZIP   B   60928  921026  Fast XX/UU de/encoder for DOS/VAX/UNIX w/C src
UNLZEXE8.ZIP  B   15021  921025  Converts LZEXE compressed EXE to original EXE

Directory PD1:<MSDOS.FINANCE>
CGZDC31A.ZIP  B  196577  921108  Capital Gainz 3.1-portfolio mgr, docs, 4/6
CGZDM31A.ZIP  B  174191  921108  Capital Gainz 3.1-portfolio mgr, tutorial, 6/6
CGZDT31A.ZIP  B    9110  921108  Capital Gainz 3.1-portfolio mgr, data, 3/6
CGZEX31A.ZIP  B   27933  921108  Capital Gainz 3.1-portfolio mgr. examples, 5/6
CGZLB31A.ZIP  B  154138  921108  Capital Gainz 3.1-portfolio mgr, library, 2/6
CGZPR31A.ZIP  B  299940  921108  Capital Gainz 3.1-portfolio mgr, program, 1/6

Directory PD1:<MSDOS.GENIE>
ILMP1192.ZIP  B   77166  921107  GEnieLamp IBM Online Magazine (Nov 1992)

Directory PD1:<MSDOS.GIF>
GIFV28.ZIP    B  177850  921106  Reads GIF/BMP, excellent slide show capability
SGIF18.ZIP    B   30441  921030  Slideshow viewer for Tseng, ATI, Paradise, 24X

Directory PD1:<MSDOS.GRAPHICS>
ARTFORM.ZIP   B  396814  921107  Artform 3D graphics animation generator
FRCAL032.ZIP  B  344071  921028  Fractal drawing program: 15 formulae available
GRPHCA20.ZIP  B  306743  921109  Interactive scientific plotting program, v2.0
IFSE099.ZIP   B  118771  921029  ImgFun: Image viewer and JPEG compression
IMPROC41.ZIP  B  362211  921026  Improces graphics editor. Req VGA/SVGA & mouse
PCXDMP71.ZIP  B  266203  921028  TSR to dump EGA, (S)VGA screens to PCX-files
VX38611.ZIP   B  102373  921107  32bit DOS GIF/JPEG/TARGA viewer for SS24X

Directory PD1:<MSDOS.HANDICAP>
READIT28.ZIP  B  105010  921103  Text file reader with bookmark, etc for speech
SFTKBD10.ZIP  B   29518  921102  Virtual on-screen keyboard that uses the mouse
TBRL31.ZIP    B  112940  921103  DEMO version of 'Turbo Braille' program
ZENWORD.ZIP   B   44969  921102  Speech friendly menu based word processor

Directory PD1:<MSDOS.HYPERTEXT>
HLPDK10.ZIP   B  161832  921029  Hypertext Help development kit
SUREFI-1.ZIP  B  210989  921104  Create Smart Documents, build in dbase, 1 of 2
SUREFI-2.ZIP  B  258355  921106  Docs & demo for award-winning SUREFIRE. 2 0f 2

Directory PD1:<MSDOS.INFO>
ASP5801.ZIP   B  468198  921031  Association of Shareware Professionals catalog
BBSTIP12.ZIP  B    5971  921026  Effective Shareware distribution via the BBS
HACK1092.ZIP  B   36390  921026  The Hack Report - trojan/virus/hacked programs
MSDOSANN.ZIP  B    3357  921025  Info on MS-DOS uploads announce mailing list
NEWSLST.ZIP   B   21864  921031  List of active Usenet newsgroups

Directory PD1:<MSDOS.LAN>
LSALV103.ZIP  B   39240  921105  List all salvagable files on Netware 3.x drive
NETBDAY5.ZIP  B   20766  921104  Birthday reminder at login for Novell networks

Directory PD1:<MSDOS.LOGO>
DOSLOGO.ZIP   B  208443  921107  LOGO Turtle Graphics for MS-DOS
MSWLGO24.ZIP  B  495971  921102  MswLogo x2.4: LOGO fo
From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!agate!doc.ic.ac.uk!uknet!pavo.csi.cam.ac.uk!mbfs.bio.cam.ac.uk!seb1005
From: seb1005@mbfs.bio.cam.ac.uk (Steven Brenner)
Newsgroups: bionet.software
Subject: 3D drawing software for the Macintosh
Message-ID: <1992Nov10.165755.11837@infodev.cam.ac.uk>
Date: 10 Nov 92 16:57:55 GMT
Sender: news@infodev.cam.ac.uk (USENET news)
Organization: U. of Cambridge, England
Lines: 13
Nntp-Posting-Host: mbfs.bio.cam.ac.uk


	A member of my laboratory is interested in drawing some 3-D structures on
his macintosh. The structures need not be "perfect," so he wants something 
simple -- like a 3D version of MacDraw.  (Rather than, for example, a mac
version of autocad, etc.)

	Can anyone offer any suggestions on if there is any such software
available?

	Thanks very much

Steven Brenner
seb1005@mbfs.bio.cam.ac.uk

From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!ASRR.ARSUSDA.GOV!jkirkbride
From: jkirkbride@ASRR.ARSUSDA.GOV ("JOSEPH H. KIRKBRIDE")
Newsgroups: bionet.software
Subject: Latest version of DELTA software available
Message-ID: <9211102034.AA02629@net.bio.net>
Date: 10 Nov 92 19:34:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 36

The latest version of the DELTA software system from Michael J. 
Dallwitz, CSIRO Division of Entomology, GPO Box 1700, Canberra ACT 
2601, Australia, telephone +61 6 246 4075, FAX +61 6 246 4000, 
Internet delta@ento.csiro.au, is now available as shareware via 
Internet FTP.  To get the DELTA software and associated databases for 
flowering plants, connect via FTP to HUH.HARVARD.EDU using the id FTP 
and the password FTP.  The DELTA software is now available for three 
different operating systems: 

  /PUB/SOFTWARE/DELTA/MSDOS
    DELTA programs for MS-DOS operating system on IBM-compatible 
      microcomputers.
  /PUB/SOFTWARE/DELTA/OS2
    DELTA programs for OS2 operating system on IBM-compatible microcomputers.
  /PUB/SOFTWARE/DELTA/SUNOS
    DELTA programs for the SUN operating system.
There are two databases available ready use with the DELTA software 
(INTKEY) for identification of organism or querying for information. 
  /PUB/SOFTWARE/DELTA/ANGIO
    Families of flowering plants of th
e world with emphasis on Australia.
  /PUB/SOFTWARE/DELTA/GRASS
    Genera of grasses of the world.
In addition there are a number of shareware programs for MS-DOS stored in:
  /PUB/SOFTWARE/DELTA/GRAHICS
These programs are very useful in preparing graphic images for use 
with the DELTA software. 
 
Joseph H. Kirkbride, Jr.
USDA, Agricultural Research Service
Systematic Botany and Mycology Laboratory
Building 265, BARC-East                          Voice telephone: 301-504-9447
Beltsville, Maryl
and 20705-2350 USA      Internet: JKIRKBRIDE@ASRR.ARSUSDA.GOV



From owner-software@net.bio.net Mon Nov 09 22:00:00 1992
Path: biosci!agate!spool.mu.edu!nigel.msen.com!emory!sol.ctr.columbia.edu!news.columbia.edu!cunixb.cc.columbia.edu!ksb3
From: ksb3@cunixb.cc.columbia.edu (Katrin S Barth)
Newsgroups: bionet.software
Subject: program to identify factors binding to palindromic sequence??
Message-ID: <1992Nov10.161219.1329@news.columbia.edu>
Date: 10 Nov 92 16:12:19 GMT
Sender: usenet@news.columbia.edu (The Network News)
Organization: Columbia University
Lines: 4
Nntp-Posting-Host: cunixb.cc.columbia.edu

Does anybody know about a program that can identify factors that bind
to a given sequence (like a palindromic sequence?)

Anukampa Barth KSB3@cunixb.cc.columbia.edu

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!agate!netsys!decwrl!uunet!emba-news.uvm.edu!emba-news.uvm.edu!brianf
From: brianf@dna.uvm.edu (Brain Foley)
Newsgroups: bionet.software
Subject: Re: Re: Graphing Program
Message-ID: <BRIANF.92Nov10203357@dna.uvm.edu>
Date: 11 Nov 92 01:33:57 GMT
References: <01GQRLSU3G6Q8WW08H@INET.D48.LILLY.COM>
Sender: news@uvm.edu
Distribution: bionet
Organization: Division of EMBA, University of Vermont
Lines: 14
In-Reply-To: SMITH_DENNIS_P@LILLY.COM's message of 5 Nov 92 01: 34:35 GMT

I have had no trouble using DeltaGraph Pro to plot 10 to the negative
power numbers.  In default mode it prints these numbers as .0001
.0000001 etc., but I can change that by selecting those data (just
click on any of these numbers and they should all get selected at
once), then changing the format of them to Scientific.

Write back if you can't figure this out.  I'm not seated at my Mac
now, so I can't give more specific instructions.
--
********************************************************************
*  Brian Foley               *     If we knew what we were doing   *
*  Molecular Genetics Dept.  *     it wouldn't be called research  *
*  University of Vermont     *                                     *
********************************************************************

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!agate!spool.mu.edu!nigel.msen.com!emory!swrinde!zaphod.mps.ohio-state.edu!rpi!utcsri!torn!csd.unb.ca!morgan.ucs.mun.ca!cs.mun.ca!odie.cs.mun.ca!harold
From: harold@odie.cs.mun.ca (Harold Wareham(Todd))
Newsgroups: bionet.software
Subject: HELP: .HQX Format for Macs
Message-ID: <1992Nov9.190919.12960@cs.mun.ca>
Date: 9 Nov 92 19:09:19 GMT
Sender: usenet@cs.mun.ca (NNTP server account)
Distribution: na
Organization: CS Dept., Memorial University of Newfoundland
Lines: 12

I recently obtainted a Macintosh file in .HQX format from the UIBio
archives. I need a copy of BinHex 4.0 or Stuffit to uncompress and
use the thing. Where can I obtain copies of either of these
programs? Thanks,

- Todd

Todd Wareham	harold@odie.cs.mun.ca	|"Success in science depends not
Department of Computer Science		| only on rational argument but
Memorial University of Newfoundland	| on a mixture of subterfuge,
St. John, NF, Canada	A1C 5S7		| rhetoric, and propaganda"
					|    - Feyerabend

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!agate!spool.mu.edu!uunet!utcsri!newsflash.concordia.ca!sifon!monod!francis
From: francis@monod.Biol.McGill.CA (Francis Ouellette)
Newsgroups: bionet.software
Subject: Re: The program Amplify for PCR design - where can I find it???
Message-ID: <francis.721484462@monod>
Date: 11 Nov 92 12:21:02 GMT
References: <1992Nov10.012249.1058@pollux.lu.se>
Sender: news@sifon.cc.mcgill.ca
Organization: McGill University
Lines: 72
Nntp-Posting-Host: monod.biol.mcgill.ca

Bo.Servenius@wblab.lu.se (Bo Servenius) writes:

>Have heard about a program Amplify for designing of PCR primers.
>Is it a freeware/shareware and if so where can I find it for FTP???


Dear Bosse,


from last week on bionet.molbio.methds-reagnts:

---------8<---cut here ----8<-----------------------


*******************************************************************
*                                                                 *
*                Frequently Asked Question (FAQ) list             *
*                for bionet.molbio.methds-reagnts                 *
*                                                                 *
*                Last update was on 01 November 1992              *
*                                                                 *
*******************************************************************
 
 
This FAQ list is available by anonymous ftp to ncifcrf.gov
Simply get the file pub/methods/FAQlist
 
[ lots of usefull stuff removed ]
 
Paul N. Hengen
National Cancer Institute
Frederick Cancer Research and Development Center
Frederick, Maryland 21702-1201 USA
 
e-mail: pnh@ncifcrf.gov
 

[ lots of usefull stuff removed ]


[ from the oligo/primer/pcr section ... ]

***********************
4. Amplify - MAC only
***********************

This software is for use in designing, analyzing, and simulating
experiments involving the polymerase chain reaction (PCR).  PCR is a
technique used by molecular biologists to amplify highly selected
segments of DNA.
 
You can obtain a copy of Amplify from
sumex-aim.stanford.edu via anonymous ftp. Look for the file:
 
      /info-mac/app/amplify-10.hqx
 
The author, Bill Engels, can be reached at WREngels@wisc.macc.edu


 
---------8<---cut here ----8<-----------------------

 regards,

 francis


--
| B.F. Francis Ouellette  
| manager, yeast chromosome I project
| dept of biology, McGill university, Montreal, Qc, Canada
| francis@monod.biol.mcgill.ca

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!agate!doc.ic.ac.uk!daresbury!news
From: PARSONS_A@snd01.pcr.co.uk
Newsgroups: bionet.software
Subject: Sequence of vector Lambda gt22 anybody??
Message-ID: <1992Nov11.143016.29901@gserv1.dl.ac.uk>
Date: 11 Nov 92 14:28:42 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 23
Original-To: BIO-SOFT <BIO-SOFT@UK.AC.DARESBURY>

Netfolk,

I am not sure this hit the bulletin board on my last mail so here goes again...

Does anybody have or know where I can get the sequence of Lambda gt22 vector.
The reference is Jang H. Han and William J. Rutter (1987) NAR vol 15 no. 15
"Lambda gt22 an improved lamda vector for the directional cloning of 
 full-length cDNA"

Any of the other lamda variants would also be a bonus (eg gt11, gt18 etc.)

Many thanks,

Tony Parsons
 +----------------------------------------------------------------------------+
 | Dr.Tony Parsons,			VOX   : + 44 304 616871	              |
 | IT Department,			FAX   : + 44 304 616670               |
 | Pfizer Central Research,				 		      |
 | Ramsgate Road,  +----------------------   e-mail   ------------------------+
 | Sandwich,       |JANET      : parsons_a@uk.co.pcr.snd01                    |
 | KENT	           |Internet   : parsons_a@snd01.pcr.co.uk	       	      |
 | CT13 9NJ UK	   |Compuserve : 100064,765    PSImail:234216700127.parsons_a |
 +-----------------+----------------------------------------------------------+

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!uwm.edu!cs.utexas.edu!usc!sol.ctr.columbia.edu!destroyer!uunet!munnari.oz.au!uniwa!uniwa!usenet
From: robert@arbo.microbiol.uwa.oz.au (Robert Coelen)
Newsgroups: bionet.software
Subject: Re: GratefulMed over TCP/IP???
Message-ID: <1dqh8rINNcjs@uniwa.uwa.edu.au>
Date: 11 Nov 92 08:46:19 GMT
Organization: University of Western Australia
Lines: 21
NNTP-Posting-Host: mve.microbiol.uwa.edu.au

In article <1992Nov6.192056.23513@alw.nih.gov> donp@niaid.nih.gov (Don Preuss) writes:
>Bo.Servenius@wblab.lu.se (Bo Servenius) writes:
>
>
>Yes. Grateful Med 6.0 can work over tcpip. You can use either a version
>that works with Wollongong, or a version that works with a packet
>driver. (Uses ncsa for the engine.). I think it it somewhere around
>$25 to order it with hard copy, but it is all ftp'able from the National
                                               ^^^^^^^^^
>Library of Medicine.
>
>donp
>donp@niaid.nih.gov

Can you give us any pointers (address & directory) Don ?


Robert Coelen
Dept of Microbiology
University of Western Australia
from the Land Down Under !

From owner-software@net.bio.net Tue Nov 10 22:00:00 1992
Path: biosci!uwm.edu!cs.utexas.edu!usc!sol.ctr.columbia.edu!destroyer!uunet!munnari.oz.au!uniwa!andrew.chi.uwa.edu.au!mike
From: mike@chi.uwa.edu.au (Mike Schon-Hegrad)
Newsgroups: bionet.software
Subject: Re: GratefulMed over tcp/ip???? for Mac!!! -Ditto
Message-ID: <1dqiqtINNef9@uniwa.uwa.edu.au>
Date: 11 Nov 92 09:13:01 GMT
References: <1992Nov8.225129.15997@pollux.lu.se>
Organization: Western Australian Research Institute for Child Health
Lines: 25
NNTP-Posting-Host: andrew.chi.uwa.edu.au
X-UserAgent: Nuntius v1.1.1d12
X-XXMessage-ID: <A726EF9F7501E03A@andrew.chi.uwa.edu.au>
X-XXDate: Wed, 11 Nov 92 09:13:03 GMT

In article <1992Nov8.225129.15997@pollux.lu.se> Bo Servenius,
Bo.Servenius@wblab.lu.se writes:
>Thanks for your comments about gm6.0. But which is the tcp/ip adress
>where I can find it for free FTP????
>
>BTW gm6.0 is for PC isn't it??? Is there a tcp/ip version for Macs
>as well??

I would like to know this too.

Many thanks

Mike
_________________________________________________
Mike Schon-Hegrad
Research Officer

Western Australian Research Institute for Child Health
Roberts Road, SUBIACO				
Western Australia    6008

Phone	(09) 340 8388
Fax	(09) 388 3414
email	mike@chi.uwa.edu.au     
__________________________________________________

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!MED.PITT.EDU!bsh
From: bsh@MED.PITT.EDU (Basavaraju Shankarappa)
Newsgroups: bionet.software
Subject: pub domain software for rearranging frag disk
Message-ID: <9211121822.AA13955@miranda.med.pitt.edu>
Date: 12 Nov 92 18:22:05 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 13


Hello netters:

	Can any one tell me whether and where I can get a public domain
software for correcting the fragmented disk space.  I was told that
some of the programs that can do the job are COMPRESS,  SPIN-WRITE
DISK OPTIMIZER etc.,  I am looking for a public domain software
that can do the job above programs can do.

	Thank you for considering the request.
Raj Shankarappa
Univ of Pittsburgh
bsh@med.pitt.edu

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!SALK-SC2.SDSC.EDU!mangalam
From: mangalam@SALK-SC2.SDSC.EDU
Newsgroups: bionet.software
Subject: Mac Primer executable
Message-ID: <9211121902.AA12502@net.bio.net>
Date: 12 Nov 92 19:02:04 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 47

Hi,
   Since the Primer gang has still not put the Mac exe up on their FTP
server, and I've received a couple of requests for it, I've bundled the
distribution, with a ThinkC project, and the executable as a binhexed,
self-extracting archive and put it up on our server (salk-sc2.sdsc.edu) in:
[anonymous.mac] (it's a VAX).  Feel free to distribute it, but only as a
complete set (to adhere to the original distribution policy).
   Beware, macaholics, it is the same text-window interface that pops up on
a VAX or PC, but it is certainly handy if you need it.
   The ThinkC project comes to you by the good graces of Richard Cooke of
Universite de Perpignan (COOKE@FRPERP51.bitnet).


   For your info:

Primer benchmarks

                                Sample.seq   Sample2.seq     Sample3.seq   
 
 
SGI Crimson
R4000/4010:50MHz                      6s        instantly          25s     
       
16kB(1')/1MB(2') Cache, 64 MB Main
Standard MIPS compiler

PC Clone
386DX/387:25MHz
64 kB Cache, 8MB Main                 30s           1s             75s
(but only 640kB accessible)
MS QuickC for Windows -> DOS exe

MacIIci
68030/68881:25MHz                     42s           3s             183s
Std Cache card, 8MB Main
Think C 5.0

Cheers
Harry
 

Harry Mangalam                                   Vox:(619) 453-4100, x250
Dept of Biocomputing                                   Fax:(619) 552-1546
The Salk Institute                             mangalam@salk-sc2.sdsc.edu
10010 N Torrey Pines Rd                        mangalam@salk-sgi.sdsc.edu
La Jolla CA 92037                                    mangalam@salk.bitnet


From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!news.cso.uiuc.edu!uxa.cso.uiuc.edu!sepg1545
From: sepg1545@uxa.cso.uiuc.edu (Scott Eric Peterson)
Newsgroups: bionet.software
Subject: Mac tutorials/reviews - Help
Summary: Looking for Mac tutorials/reviews
Keywords: software
Message-ID: <BxJF05.1En@news.cso.uiuc.edu>
Date: 11 Nov 92 05:52:51 GMT
Sender: usenet@news.cso.uiuc.edu (Net Noise owner)
Organization: University of Illinois at Urbana
Lines: 7



Hello, I'm new to this group and couldn't find a FAQ, so I don't know just how dumb this question is- but here it is.  I'm am looking for mac-software that may
be useful for 2nd year medical students- reviewing for boards etc.  I'm am aware of some shareware hypercard stacks that are pretty useful and was just 
wondering what was available.  If anyone has any that is ftp-able or on a server somewhere I would appreciate any mail telling me about it.

Thanks in advance.

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: SeqApp sliding-base bug fix (Macintosh)
Message-ID: <BxLyzo.9JC@usenet.ucs.indiana.edu>
Date: 12 Nov 92 14:59:47 GMT
Sender: news@usenet.ucs.indiana.edu (USENET News System)
Organization: Biology, Indiana University - Bloomington
Lines: 38
Nntp-Posting-Host: sunflower.bio.indiana.edu


12 Nov 92, version 1.8a154 -- interim bug fix release.  Cures problem
introduced in version 1.8a153: sequence data was lost when
the "sliding bases" feature of adding gaps was used, then the
document was saved.

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
SeqApp is a biological sequence editor and analysis program for
Macintosh computers.  It includes links to network services and 
external analysis programs.

Features include	
	multiple sequence alignment editor
	single sequence editor window
	read and write several sequence file formats
	easy hand alignment features including colored bases and sliding
	automatic multiple sequence alignment thru Clustal external app 
	automatic gel fragment alignment to contigs thru exernal app
	consensus,reverse,complement,degap operations
	restriction maps
	dot plots
	translate dna to/from protein using various codon tables
	automatic preference saving
	internet send mail, read mail
	internet gopher, information retreival including genbank.
	internet sequence analysis services
	user-definable links to external analysis programs
	and more

You can obtain updates of this program thru anonymous ftp to 
ftp.bio.indiana.edu, in folder /molbio/seqapp, as seqapp.hqx. 
You may also obtain updates directly thru an internet-connected
Mac with SeqApp, using Gopher to the IUBio archive.  Look for a
folder called "IUBio Software+Data/SeqApp, Mac sequence editor".

-- 
Don Gilbert                                     gilbert@bio.indiana.edu
biocomputing office, biology dept., indiana univ., bloomington, in 47405

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!bcm!cs.utexas.edu!swrinde!emory!sol.ctr.columbia.edu!ira.uka.de!news.belwue.de!news.uni-tuebingen.de!studserv!zxmkr08
From: zxmkr08@studserv.zdv.uni-tuebingen.de (Cornelius Krasel)
Newsgroups: bionet.software
Subject: Re: GratefulMed over tcp/ip???? for Mac!!!
Message-ID: <zxmkr08.721510798@studserv>
Date: 11 Nov 92 19:39:58 GMT
References: <1992Nov8.225129.15997@pollux.lu.se>
Sender: news@softserv.zdv.uni-tuebingen.de (News Operator)
Organization: Comp. Center (ZDV) U of Tuebingen, FRG
Lines: 19

In <1992Nov8.225129.15997@pollux.lu.se> Bo Servenius <Bo.Servenius@wblab.lu.se> writes:

>BTW gm6.0 is for PC isn't it??? Is there a tcp/ip version for Macs
>as well??

The TCP/IP software for Macs is MacTCP. The actual version is 1.1 (as far
as I know). I have installed it under System 7 and it works like a dream
(not like these darned IBM PCs... I always have troubles to find drivers
for our 3C507 ethernet card, e.g. to get it to work with NCSA Telnet 2.3).
To my knowledge, MacTCP is NOT in the public domain. You can ftp it
nevertheless; if you get an Eudora Package somewhere, it is included.
There is also some documentation somewhere in ftp-land about how to
configure MacTCP, but I am not sure where I picked it up ... it is
accessible via Archie, though (that was the way I found it).
--
/* Cornelius Krasel, Department of Physiological Chemistry, U Tuebingen    */ 
/* email: krasel@studserv.zdv.uni-tuebingen.de (Internet)   HAS CHANGED!!  */
/*        NO WIN/X400 MAIL POSSIBLE AT THE MOMENT!                         */
/* "People are DNA's way of making more DNA." (anonymous)                  */

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!agate!ames!elroy.jpl.nasa.gov!swrinde!zaphod.mps.ohio-state.edu!cs.utexas.edu!uunet!seas.gwu.edu!merlot.gwu.edu!danj
From: danj@merlot.gwu.edu (Dan Jacobson )
Newsgroups: bionet.software
Subject: Re: HELP: .HQX Format for Macs
Message-ID: <1992Nov11.182552.13771@seas.gwu.edu>
Date: 11 Nov 92 18:25:52 GMT
References: <1992Nov9.190919.12960@cs.mun.ca>
Sender: news@seas.gwu.edu
Distribution: na
Organization: George Washington University, Washington, D.C.
Lines: 17

In article <1992Nov9.190919.12960@cs.mun.ca> harold@odie.cs.mun.ca (Harold Wareham(Todd)) writes:
>I recently obtainted a Macintosh file in .HQX format from the UIBio
>archives. I need a copy of BinHex 4.0 or Stuffit to uncompress and
>use the thing. Where can I obtain copies of either of these
>programs? Thanks,
>
>- Todd

You can find Stuffit (among other places) in the util/mac directory
at IUBIO (ftp.bio.indiana.edu).


Cheers,

Dan Jacobson

danj@chablis.gwu.edu

From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!ASRR.ARSUSDA.GOV!jkirkbride
From: jkirkbride@ASRR.ARSUSDA.GOV ("JOSEPH H. KIRKBRIDE")
Newsgroups: bionet.software
Subject: Latest version of DELTA software available on Internet via FTP
Message-ID: <9211121307.AA27578@net.bio.net>
Date: 12 Nov 92 12:02:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 33

The latest version of the DELTA software system from Michael J. 
Dallwitz, CSIRO Division of Entomology, GPO Box 1700, Canberra ACT 
2601, Australia, telephone +61 6 246 4075, FAX +61 6 246 4000, 
Internet delta@ento.csiro.au, is now available as shareware via 
Internet FTP.  To get the DELTA software and associated databases for 
flowering plants, connect via FTP to HUH.HARVARD.EDU using the id FTP 
and the password FTP.  The DELTA software is now available for three 
different operating systems: 
  /PUB/SOFTWARE/DELTA/MSDOS
    DELTA programs for MS-DOS operating system on IBM-compatible 
      microcomputers.
  /PUB/SOFTWARE/DELTA/OS2
    DELTA programs for OS2 operating system on IBM-compatible microcomputers.
  /PUB/SOFTWARE/DELTA/SUNOS
    DELTA programs for the SUN operating system.
There are two databases available ready to use with the DELTA software 
(INTKEY) for identification of organism or querying for information. 
  /PUB/SOFTWARE/DELTA/ANGIO
    Families of flowering plants of the world with emphasis on Australia.
  /PUB/SOFTWARE/DELTA/GRASS
    Genera of grasses of the world.
In addition there are a number of shareware programs for MS-DOS stored in:
  /PUB/SOFTWARE/DELTA/GRAHICS
These programs are very useful in preparing graphic images for use 
with the DELTA software. 
 
Joseph H. Kirkbride, Jr.
USDA, Agricultural Research Service
Systematic Botany and Mycology Laboratory
Building 265, BARC-East                          Voice telephone: 301-504-9447
Beltsville, Maryland 20705-2350 USA      Internet: JKIRKBRIDE@ASRR.ARSUSDA.GOV



From owner-software@net.bio.net Wed Nov 11 22:00:00 1992
Path: biosci!agate!ames!elroy.jpl.nasa.gov!sdd.hp.com!nigel.msen.com!emory!europa.asd.contel.com!darwin.sura.net!uvaarpa!murdoch!cyclops.micr.Virginia.EDU!wrp
From: wrp@cyclops.micr.Virginia.EDU (Bill Pearson)
Newsgroups: bionet.software,bionet.molbio.embl,bionet.molbio.genbank,bionet.molbio.pir
Subject: FASTA16c22 available
Message-ID: <1992Nov12.190941.21010@murdoch.acc.Virginia.EDU>
Date: 12 Nov 92 19:09:41 GMT
Sender: usenet@murdoch.acc.Virginia.EDU
Organization: University of Virginia
Lines: 33
Xref: biosci bionet.software:3607 bionet.molbio.genbank:1069
Originator: wrp@cyclops.micr.Virginia.EDU


	Recently, several bugs in the FASTA package have been fixed
and a new version is avaiable via anonymous ftp from:

	uvaarpa.virginia.edu:/pub/fasta/fasta16c22.shar(.Z)

(1) Code has been included to allow the EMBL and PIR CD-ROM's to be
read on unix systems.  Because these CD-ROM's include a <CR><LF>
character but unix expects a <LF> end of line, sequence annotations were
sometimes garbled. Hopefully this has been fixed.

(2) A bug in RDF2 has been fixed.  When comparing DNA sequences, RDF2
used an incorrect scoring method for initial regions.  RDF2 worked
properly on protein sequences.  RDF2 does work properly on DNA sequences
if the "-k" option is used.  This problem was discovered because the
unshuffled scores for RDF2 were different from the FASTA scores for many
DNA sequences.  This should not happen; if you find examples with the new
version of RDF2, please contact me.

In addition, a bug in the Mac FASTA version 1.6c2 has been reported.
Code that was included in the Mac 1.4x version to allow the EMBL
CD-ROM to be read properly was omitted from the 1.6 version.  As a
result, MacFASTA does not read properly the sequence files (either
EMBL or PIR format) from the EMBL CD-ROM. It will also not read other
CD-ROM formats properly.  I hope to send out corrected versions of
MacFASTA 1.6c this weekend or early next week.

The CD-ROM problem does not affect DOS versions; the RDF2 problem is
present in DOS and Macintosh versions.

The Macintosh and DOS versions are not available via anonymous FTP.

Bill Pearson

From owner-software@net.bio.net Thu Nov 12 22:00:00 1992
Path: biosci!lhc!darwin.sura.net!haven.umd.edu!umd5!williams.smcm.edu!bwilliam
From: bwilliam@oyster.smcm.edu (Bill Williams)
Newsgroups: bionet.software
Subject: Re: InPlot for Mac?
Message-ID: <16966@umd5.umd.edu>
Date: 13 Nov 92 20:55:10 GMT
References: <1992Nov10.000502.20308@reed.edu>
Sender: news@umd5.umd.edu
Organization: St. Mary's College of Maryland
Lines: 18
X-UserAgent: Nuntius v1.1.1d10
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X-XXDate: Fri, 13 Nov 92 21:59:16 GMT

In article <1992Nov10.000502.20308@reed.edu> Eric Bowman,
bowman@reed.edu writes:
>Does such a product exist for Macintosh?

I use IGOR, and I recommend it with the qualification that it is not
overly user-friendly. It is extremely capable and fast.  It will do all
the things you request:  curve fitting to a myriad of possible
functions (polynomial, Fourier, exponential, etc., etc.), it'll happily
do error bars (it'll calculate them for you, but I find it easier to do
the calculations in Excel), bar plots, scatter plots, you name it.
 
 IGOR is available from WvaeMetrics, PO Box 2088, Lake Osego, OR 97035.
 503-620-3001.  They are reachable at WaveMetrics@AppleLink.Apple.com
___________________________________
William E. Williams, bwilliam@oyster.smcm.edu
Divison of Natural Sciences and Mathematics
St. Mary's College of Maryland
St. Mary's City, MD 20686

From owner-software@net.bio.net Thu Nov 12 22:00:00 1992
Path: biosci!agate!spool.mu.edu!caen!destroyer!lambda.msfc.nasa.gov!saimiri.primate.wisc.edu!usenet.coe.montana.edu!Msu.oscs.montana.edu!uvsmr
From: uvsmr@Msu.oscs.montana.edu (Matt Rognlie)
Newsgroups: bionet.software
Subject: Software for PC scanners
Message-ID: <00963814.A3D75CE0@Msu.oscs.montana.edu>
Date: 12 Nov 92 20:13:00 GMT
Sender: usenet@coe.montana.edu (USENET News System)
Reply-To: uvsmr@Msu.oscs.montana.edu (Matt Rognlie)
Organization: Montana State University
Lines: 12

We would like to purchase a flatbed scanner (i.e. HP ScanJet) to use
with a DEC 486.  Is there software available which would allow us to
use the scanner as a densitometer?  We want to scan autoradiograms or
gels, but be able to get density data so that bands can be compared.
Any suggestions on the latest scanner technology would also be 
appreciated.
Thanks for your help.
Matthew Rognlie                  |
Veterinary Molecular Biology     | uvsmr@trex.oscs.montana.edu
Marsh Lab                        | phone: 406-994-6379
Montana State University         |   FAX: 406-994-4303
Bozeman, MT  59717-0360          |

From owner-software@net.bio.net Thu Nov 12 22:00:00 1992
Path: biosci!lhc!darwin.sura.net!haven.umd.edu!umd5!williams.smcm.edu!bwilliam
From: bwilliam@oyster.smcm.edu (Bill Williams)
Newsgroups: bionet.software
Subject: Re: HELP: .HQX Format for Macs
Message-ID: <16967@umd5.umd.edu>
Date: 13 Nov 92 20:58:05 GMT
References: <1992Nov9.190919.12960@cs.mun.ca>
Sender: news@umd5.umd.edu
Organization: St. Mary's College of Maryland
Lines: 19
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X-XXDate: Fri, 13 Nov 92 22:02:11 GMT

In article <1992Nov9.190919.12960@cs.mun.ca> Harold Wareham,
harold@odie.cs.mun.ca writes:
>I recently obtainted a Macintosh file in .HQX format from the UIBio
>archives. I need a copy of BinHex 4.0 or Stuffit to uncompress and
>use the thing. Where can I obtain copies of either of these
>programs?

For anyone with a Mac but unfamiliar with the downloading conventions
for Macs, I highly recommending downloading a number of very
informative files (in text format, hence not requiring any fancy
programs) at sumex-aim.stanford.edu in the directory /info-mac/reports.
 I don't have the specific names of the files handy, but looks for
things like FTP-site directories, FTP how-to, etc.  As I recall the
reports are well written and direct.
___________________________________
William E. Williams, bwilliam@oyster.smcm.edu
Divison of Natural Sciences and Mathematics
St. Mary's College of Maryland
St. Mary's City, MD 20686

From owner-software@net.bio.net Thu Nov 12 22:00:00 1992
Path: biosci!uwm.edu!spool.mu.edu!yale.edu!ira.uka.de!ira.uka.de!gmd.de!Germany.EU.net!mcsun!news.funet.fi!funic!convex!harper
From: harper@convex.csc.FI (Rob Harper)
Newsgroups: bionet.software
Subject: Re: Software for PC scanners
Message-ID: <1992Nov13.115311.16255@nic.funet.fi>
Date: 13 Nov 92 11:53:11 GMT
References: <00963814.A3D75CE0@Msu.oscs.montana.edu>
Sender: usenet@nic.funet.fi
Organization: Finnish Academic and Research Network Project - FUNET
Lines: 46
Nntp-Posting-Host: convex.csc.fi

In <00963814.A3D75CE0@Msu.oscs.montana.edu> uvsmr@Msu.oscs.montana.edu (Matt Rognlie) writes:

>We would like to purchase a flatbed scanner (i.e. HP ScanJet) to use
>with a DEC 486.  Is there software available which would allow us to
>use the scanner as a densitometer?  We want to scan autoradiograms or
>gels, but be able to get density data so that bands can be compared.
>Any suggestions on the latest scanner technology would also be 

This question has come up alot and there has been many responses to it
The biosci.src which is available at you local bio-gopher hole will give
you three pages of information on scanners.

%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% CLIP %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
                          biosci.src: scanner

      1.  GERLACHJ@Q Re: Hand Scanner and Autorads.
      2.  GERLACHJ@Q Re: Hand Scanner and Autorads.
      3.  BACKD@QUCD Re: Re: Hand Scanner and Autorads.
      4.  BACKD@QUCD Re: Re: Hand Scanner and Autorads.
      5.  marder@agr Re: Recording scanner.
      6.  GERLACHJ@Q Re: Software for Densitometry from Scanner Images.
      7.  smith@phyl Re: Re: Hand Scanner and Autorads.
      8.  Frank Yue Re: Re: Hand Scanner and Autorads.
      9.  NXK104@psu Re: OCR Software & Scanner.
      10. GERLACHJ@Q Re: Software for Densitometry from Scanner Images.
      11. smith@phyl Re: Re: Hand Scanner and Autorads.
      12. BACKD@QUCD Re: Re: Hand Scanner and Autorads.
 -->  13. djt2@po.CW Re: Scanners for autorads- responses.
      14. extim@lure Re: Scanners for DNA gel densitometry analysis.
      15. david@ASTR Re: to be posted.
      16. morrow@mur Re: REA patterns.
      17. broe@aardv Re: Re: Macintosh Sequence Aligner/Editor?.
      18. BDODSON%VU Re: RE: IMAGE ANALYSIS OF BLOTS AND CAT ASSAYS.

Press ? for Help, q to Quit, u to go up a menu                        Page: 1/3
 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

I have used the mail option from within gopher and I have posted you the 
best bits. I hope you find them useful.

Rob "at your service" Harper
--
 ~ Rob Harper                    ~ E-mail:          harper@convex.csc.fi    
 ~ Finnish State Computer Centre ~ Molbio/software: harper@nic.funet.fi
 ~ P.O. Box 40                   ~ Telephone:       +358 0 457 2076
 ~ SF-02101 Espoo Finland        ~ Fax:             +358 0 457 2302

From owner-software@net.bio.net Fri Nov 13 22:00:00 1992
Path: biosci!lhc!host!gish
From: gish@host.nlm.nih.gov (Warren Gish)
Newsgroups: bionet.software
Subject: NCBI Search CD-ROM File Format
Message-ID: <1992Nov13.235359.24134@nlm.nih.gov>
Date: 13 Nov 92 23:53:59 GMT
Sender: news@nlm.nih.gov
Organization: National Library of Medicine
Lines: 330

The following announcment of the NCBI Search CD-ROM file format for sequence
data is directed primarily to software developers.  Users who wish to be
notified when the Search CD-ROM is available for ordering should subscribe
to "NCBI News".  A free subscription to this newsletter can be obtained by
sending your name and postal address to:  info@ncbi.nlm.nih.gov

Sample Search CD-ROM data files and reference source code is available now, via
anonymous ftp, on ncbi.nlm.nih.gov (130.14.20.1) beneath the /pub/searchcd
directory.  Additional recommended software and documentation is posted on the
same ftp server beneath the /toolbox/ncbi_tools_rel2.0 and /pub/gish
directories.  While the software beneath /pub/searchcd has been used locally to
produce the sample Search files, it is posted only as a developer reference.
The code does not compile and link into an executable application and it should
not be considered a stable basis for development of application software.

A limited quantity of a prototype Search CD-ROM will be available within 8
weeks.  Developers interested in obtaining a copy should send their name and
postal address before Friday, November 20 to:  searchcd@ncbi.nlm.nih.gov or
contact me by phone.

Sincerely,
Warren Gish
NCBI/NLM
Voice:  301-496-2475
FAX:  301-480-9241



           NCBI Search CD-ROM File Format -- Sample Distribution


INTRODUCTION

The NCBI Search CD-ROM will be a vehicle for distributing molecular sequence
data in a format that is efficient for sequence similarity searches using
methods such as FASTA and BLAST.  The Search format further supports multiple
definitions linked to each sequence (as may be desired in a nonredundant
collection) and facilitates the application of incremental updates such as
might be obtained via a network.  The NCBI intends to migrate much of its
software over to using the "Search CD" format.

The set of sequences distributed on the Entrez:Sequences CD-ROM will be
distributed every two months on a Search CD-ROM, as well, in the format
outlined below and detailed in the accompanying C language source files.  As
space permits, sequences from the NCBI's GenInfo(R) Integrated Database, which
will be available within the next several months, will also be included on the
Search CD-ROM in a separate directory.

Prof. William Pearson (Univ. of Virginia) has generously offered to produce PC
and Mac versions of FASTA to search files on the Search CD-ROM; these programs
will be distributed on the Search CD-ROM itself, with software support handled
by Dr. Pearson.  As they become available, UNIX, Mac, and PC versions of BLAST
software from the NCBI will be posted "as is" for anonymous ftp access on
ncbi.nlm.nih.gov.

Commercial providers of software and services which support the NCBI Search
CD-ROM are encouraged to notify the NCBI of their product availability.  Their
names and addresses will be placed on file and will be made available to
potential customers who inquire about support.  Please send all such
announcements to searchcd@ncbi.nlm.nih.gov



SAMPLE FILES

There are 5 subdirectories in this sample distribution:

  src -- C language source files describing the Search CD-ROM file formats.
         Additional supporting source code is posted on ncbi.nlm.nih.gov
         beneath the /toolbox/ncbi_tools_rel2.0 and /pub/gish directories.
  search -- a mock Search CD-ROM with some sample files
  search/entrez -- sample files in Search CD-ROM format using a very small
                   subset of the Entrez:Sequences data
  search/giid -- sample List file describing the division of GenInfo(R)
                 Integrated database data into separate files
  fasta -- the FASTA-format data used to generate the Search CD-ROM files
           in the "search/entrez" directory.  FASTA files will not be
           distributed on the Search CD-ROM.

The most important single file for understanding the internal structure of
files on the Search CD-ROM is src/headers.h.  It is recommended that
src/headers.h be browsed prior to studying the remainder of this document.
Individual C structure elements are specified in the same order in which the
data are stored within the files.  All "unsigned long" integers are stored in a
4-byte big-endian format.  Byte alignment is not observed--all elements are
close packed.



FIVE DISTINCT FILE TYPES

For sequence similarity searching, only two types of files are of primary
concern:  Sequence and Definition.  Each record in a Sequence file includes the
record length, a sequence identifier, an encoded and/or packed sequence, and
the file offset into the Definitions file for a linked list of Definition
records.  Each Definition record contains zero or more sequence identifiers and
associated human-readable definitions, plus a (possibly NULL) file offset to
the next Definition record in the linked list.

A third file type, Table, contains file offsets into matching Sequence and
Definition files.  One potential use for a Table file is in the assignment of
sequence records to individual processors in a multiprocessing or multithreaded
implementation of a search program.  A Table file may also store offsets to
only a subset of the records in the database.  A more obscure use of a Table
file would be to provide offsets to alternate or ancillary definitions from
those pointed to within the Sequence file itself.

The fourth file type, Index, is used to look up Sequence and Definition record
offsets, given a sequence identifier.  An Index file can contain offsets into
either amino acid or nucleic acid sequence files.

The fifth file type, List, is used to describe an entire collection of Search
files, including their base filenames, residue type (aa or nt), and division
(e.g., primates, plants, invertebrates, etc.)  This is the only file type whose
content is entirely human readable text.  List files may be a focal point for
customizing the installation of the other Search files.



FILE SIZE RESTRICTIONS

The Search CD-ROM will be produced in ISO 9660 format, so on some computing
platforms each of the file names will have a ";1" suffix tacked on.  The ISO
9660 format restricts files to being 64 MB or less in size, while MS-DOS
further restricts files to being 32 MB or less.  Consequently, it may be
necessary to split some data sets or divisions into multiple sets of Sequence,
Definition, and Table files in order to stay under the 32 MB limit.  Software
written to support Search files for other operating systems and media should
not be so limited.  Index files can support nearly 2 million records
(identifiers) and still reside below the 32 MB limit, so it is not anticipated
that Index files will need to be split for a considerable length of time.



FILE NAMING CONVENTIONS

Sequence, Definition, and Table files that work together will share a common
base filename.  Similarly, List and Index files that work together will share a
common base filename.  For Sequence, Definition and Table files, their filename
extensions will depend on the type of sequence (aa or nt) to which the files
refer:  *.[an]sq *.[an]df *.[an]tb.  List and Index files can refer to both
types of files.  The filename extension for a List file is .fls.  The filename
extension for an Index file is .idx.

Sequence, Definition, Table, and Index files each begin with a header structure
described in headers.h.  The four header types begin with a structure of common
or standard elements (ScdStdHdr).  Following the standard header elements and
the file type-specific elements which complete each header, there will be zero
or more records in a format specific to the particular file type.



SEQUENCE IDENTIFIERS

Sequence identifiers are unsigned integers.  The identifiers are drawn
from the same name space used for sequence identifiers on release 1.0
of the Entrez:Sequences CD-ROM.  At present, these are "import identifiers" or
"giim" identifiers, but will ultimately be "GenInfo Integrated Database" or
"giid" identifiers.  By using the same identifiers as the Entrez:Sequences
CD-ROM, it is possible to use the identifiers obtained by a similarity
search to directly look-up records on the Entrez:Sequences CD-ROM.



REDUNDANCY OF SEQUENCE INFORMATION

When practical, Search CD-ROM database files will be "nonredundant"--100%
identical sequences will be merged into a single sequence-definition record
pair.  For instance, when two or more sequences are absolutely identical at the
sequence level, only one of their identifiers will be stored in the Sequence
record, but all of their identifiers will be available in the corresponding
Definition record.  The 'def_off' element in the Sequence record points to the
head of the relevant linked list of Definition record(s) in the Definition
file.



DIVISIONAL CLUSTERING OF SEQUENCES

Protein sequences are likely to be distributed in a single "All" division,
which may need to be split into multiple sets of Sequence-Definition-Table
files in order to avoid breaking the aforementioned 32 MB file size barrier.

Nucleotide sequences will be distributed in the familiar GenBank(R) divisions,
except Organelle which will disappear, plus a new EST division.  The contents
of the List format file giid/giid.fls provides a better outline than does the
entrez/entrez.fls file of the divisions that are planned.  For instance, in the
sample Entrez files, NLM Backbone sequences appear in a separate division which
will not be present in future releases.  Again, it may be necessary to split
divisions into multiple sets of Search files to avoid the file size barrier.
"DV" records in .fls files indicate the particular division to which each set
of files belongs.



DEFINITIONS & ACCESSION NUMBERS

As stored in a Definition record, Definition strings consist of a 4-byte length
field followed by a NON-null-terminated, printable ASCII string of the
specified length.  In Search CD-ROM files, the binary encoded 'seqid' elements
will NOT be repeated in printable ASCII form within the human readable
definition strings.  The definition strings may, however, contain identifiers
from other name spaces.  Definition strings in the sample files begin with an
acronym representing the database from which the definition was obtained,
followed by a colon (:), the accession number in the specified database, and
finally the definition.  The database acronyms used are:  GB=GenBank(R),
PIR=the NBRF PIR(R), SP=SWISS-PROT.  Other acronyms that
From owner-software@net.bio.net Fri Nov 13 22:00:00 1992
Path: biosci!agate!spool.mu.edu!yale.edu!news.yale.edu!YaleVM.YCC.Yale.Edu!LILMARA
From: LILMARA@YaleVM.YCC.Yale.Edu (Martin Lilly)
Newsgroups: bionet.software,bionet.molbio.embl,bionet.molbio.genbank,bionet.molbio.pir
Subject: Re: FASTA16c22 available
Message-ID: <1689E12475.LILMARA@YaleVM.YCC.Yale.Edu>
Date: 14 Nov 92 01:47:39 GMT
References: <1992Nov12.190941.21010@murdoch.acc.Virginia.EDU>
Sender: news@news.yale.edu (USENET News System)
Organization: Yale University
Lines: 14
Xref: biosci bionet.software:3613 bionet.molbio.genbank:1070
Nntp-Posting-Host: yalevm.ycc.yale.edu

In article <1992Nov12.190941.21010@murdoch.acc.Virginia.EDU>
wrp@cyclops.micr.Virginia.EDU (Bill Pearson) writes:
 
>
>	Recently, several bugs in the FASTA package have been fixed
>and a new version is avaiable via anonymous ftp from:
(TEXT DELETED)
>The Macintosh and DOS versions are not available via anonymous FTP.
>
>Bill Pearson
 
How can we get Macintosh/DOS versions?
 
Thanks, LILMARA@YaleVM.YCC.YALE.EDU

From owner-software@net.bio.net Sat Nov 14 22:00:00 1992
Path: biosci!uwm.edu!point.cs.uwm.edu!stonger
From: stonger@point.cs.uwm.edu (Kelly Stonger)
Newsgroups: bionet.software
Subject: Thesis topic
Message-ID: <1e644kINNc9d@uwm.edu>
Date: 15 Nov 92 18:15:48 GMT
Distribution: usa
Organization: University of Wisconsin, Milwaukee
Lines: 16
NNTP-Posting-Host: 129.89.2.5





Hi,

I am a graduate student in computer science and I am looking for
a masters thesis topic. Since I also have a masters in microbiology,
I would like to work on a topic that relates to both computer science
and biology (such as RNA folding or DNA sequencing). Can you
recommend any research topics in this (or any other) area that I
can use as a basis for a thesis. Any help would be greatly
appreciated.


K. Stonger

From owner-software@net.bio.net Sat Nov 14 22:00:00 1992
Path: biosci!MED.PITT.EDU!bsh
From: bsh@MED.PITT.EDU (Basavaraju Shankarappa)
Newsgroups: bionet.software
Subject: public domain software
Message-ID: <9211151751.AA21920@miranda.med.pitt.edu>
Date: 15 Nov 92 17:51:12 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 19

Hi netters:

	Sometime back I had posted a request on info about the availabilit
of public domain software for de-fragmenting the disk.  I thank everyone 
who made suggestions to me on this behalf.  Many of you also indicated
that I will be better off buying this kind of software as it is worth the
small amount of money it costs.  In this regard I would like to explain the
reason for my preference to public domain software.  To make one thing clear,
I am not opposed to paying money for a product/idea which someone has worked
hard at.  In my case, the reason for my request was to see that I can get 
the program in as short a time as possible.  If I have to go through the 
University bureacracy, I will have to wait for atleast 15-20 days.  
I hope I have been able to make my position more clear.
Thanks for putting up with me. '

Raj Shankarappa
Univ of Pittsburgh
bsh@med.pitt.edu


From owner-software@net.bio.net Sat Nov 14 22:00:00 1992
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!wupost!waikato.ac.nz!aukuni.ac.nz!nholford
From: nholford@ccu1.aukuni.ac.nz (Nick Holford)
Newsgroups: bionet.software
Subject: Paperchase? How can I access it? (Boston/Beth Israel)
Message-ID: <1992Nov15.201701.7068@ccu1.aukuni.ac.nz>
Date: 15 Nov 92 20:17:01 GMT
Organization: University of Auckland, New Zealand.
Lines: 9

I have heard that there is a database of clinical trials under the name
Paperchase. It originates from Beth Israel Hospital clinical computing I
think. Can anyone tell me more about it and how I can access it?

-- 

Nick Holford, Dept Pharmacology & Clinical Pharmacology
University of Auckland, Auckland, New Zealand
INTERNET: n.holford@aukuni.ac.nz

From owner-software@net.bio.net Sat Nov 14 22:00:00 1992
Path: biosci!agate!usenet.ins.cwru.edu!po.CWRU.Edu!ccy
From: ccy@po.CWRU.Edu (Cheung C. Yue)
Newsgroups: bionet.software
Subject: Re: HELP: .HQX Format for Macs
Message-ID: <1e5r6pINN126@usenet.INS.CWRU.Edu>
Date: 15 Nov 92 15:43:21 GMT
References: <16967@umd5.umd.edu> <1992Nov9.190919.12960@cs.mun.ca>
Reply-To: ccy@po.CWRU.Edu (Cheung C. Yue)
Organization: Case Western Reserve University, Cleveland, OH (USA)
Lines: 32
NNTP-Posting-Host: slc5.ins.cwru.edu


In a previous article, bwilliam@oyster.smcm.edu (Bill Williams) says:

>In article <1992Nov9.190919.12960@cs.mun.ca> Harold Wareham,
>harold@odie.cs.mun.ca writes:
>>I recently obtainted a Macintosh file in .HQX format from the UIBio
>>archives. I need a copy of BinHex 4.0 or Stuffit to uncompress and
>>use the thing. Where can I obtain copies of either of these
>>programs?
>
>For anyone with a Mac but unfamiliar with the downloading conventions
>for Macs, I highly recommending downloading a number of very
>informative files (in text format, hence not requiring any fancy
>programs) at sumex-aim.stanford.edu in the directory /info-mac/reports.
> I don't have the specific names of the files handy, but looks for
>things like FTP-site directories, FTP how-to, etc.  As I recall the
>reports are well written and direct.

I confronted my own problems with Binhex some time ago by finding a friend
with a copy of Stuffit Deluxe who could then unbinhex binhex40.hqx for me, and 
so on.  Although sumex-aim.stanford.edu has a binary version of binhex
(binhex.bin), I was unable to transfer it to my mac in Macbinary transfer.
Perhaps you may have better luck with your own transfer.  If that fails,
you may have to resort to finding a friend locally who could unbinhex that
first file for you (first file being binhex40.hqx).  The above recommendation
is an excellent suggestion, although I believe the files are in info-mac/help.

Good luck.

ccy@po.cwru.edu

-- 

From owner-software@net.bio.net Sun Nov 15 22:00:00 1992
Path: biosci!XIBALBA.CSHL.ORG!mzhang
From: mzhang@XIBALBA.CSHL.ORG (Michael Zhang)
Newsgroups: bionet.software
Subject: public domain games?
Message-ID: <9211161336.AA00427@xibalba.cshl.org>
Date: 16 Nov 92 13:36:57 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 4

Hi netters:
Are there any public domain games or children educational softwares?
M.Zhang
mzhang@cshl.org

From owner-software@net.bio.net Sun Nov 15 22:00:00 1992
Path: biosci!agate!ames!haven.umd.edu!umd5!williams.smcm.edu!bwilliam
From: bwilliam@oyster.smcm.edu (Bill Williams)
Newsgroups: bionet.software
Subject: Re: HELP: .HQX Format for Macs
Message-ID: <17011@umd5.umd.edu>
Date: 16 Nov 92 16:33:39 GMT
References: <1992Nov9.190919.12960@cs.mun.ca> <1e5r6pINN126@usenet.INS.CWRU.Edu>
Sender: news@umd5.umd.edu
Organization: St. Mary's College of Maryland
Lines: 22
X-UserAgent: Nuntius v1.1.1d10
X-XXMessage-ID: <A72D46A0AD0201D2@williams.smcm.edu>
X-XXDate: Mon, 16 Nov 92 17:37:52 GMT

In article <1e5r6pINN126@usenet.INS.CWRU.Edu> Cheung C. Yue,
ccy@po.CWRU.Edu writes:
>The above recommendation
>is an excellent suggestion, although I believe the files are in
info-mac/help.

Well, OK, I guess I'd better check...

They are in info-mac/reports.  I recommend the following reports:

comp-sys-mac-comm-faq.txt
ftp-primer.txt
ftp-sites.txt

I agree that you may have a bootstrap problem;  I did all this so long
ago that I've frankly forgotten
how to get the first program.
___________________________________
William E. Williams, bwilliam@oyster.smcm.edu
Divison of Natural Sciences and Mathematics
St. Mary's College of Maryland
St. Mary's City, MD 20686

From owner-software@net.bio.net Sun Nov 15 22:00:00 1992
Path: biosci!daresbury!mrccrc!warwick!uknet!pavo.csi.cam.ac.uk!mbfs.bio.cam.ac.uk!seb1005
From: seb1005@mbfs.bio.cam.ac.uk (Steven Brenner)
Newsgroups: bionet.software
Subject: Biblography Programs: Summary of Responses
Message-ID: <1992Nov16.013301.28748@infodev.cam.ac.uk>
Date: 16 Nov 92 01:33:01 GMT
Sender: news@infodev.cam.ac.uk (USENET news)
Organization: U. of Cambridge, England
Lines: 179
Nntp-Posting-Host: mbfs.bio.cam.ac.uk


I recently posted asking about bibliography programs for unix.  Here
are the responses I received.  Many thanks to all those who replied!

I should note that the addbib/refer package seems to be standard on
most unix systems (Sun has it as an option, BSD has it, AIX has it,
IRIX doesn't have it on the machines I use)

Cheers,
Steven Brenner

---
From: davis@nod.bms.com (Malcolm Davis)
Subject: Unix Bibliography Programs?

Hi,

I use LaTeX to write my documents and so use the BibTeX bibliography
database.  There are a few programs around for working with this
format.  I just use the emacs bibtex-mode and a couple of Perl scripts
I have written, but I have heard good things about the bibcard program.
I also make big use of Current Contents on Disk and so have writtin a
Perl script which will take CCOD's output and convert to BibTeX format
along with my personal scheme for generating key names.

Malcolm Davis / davis@nod.bms.com / BMSPRI Princeton, NJ

---

From: dws@forager.unl.edu (David Stephens)

There are two that I know of.  The first, and I think the most widely
used, is bibtex.  It's designed to be used with LaTeX, and it's very
programmable, but you have to be quite a nerd to program it.  It's
public domain, and maintained by the TeX group in stanford.  There's
lots of support for it in various forms, pre-programmed styles for
various journals.  Emacs modes for editing the database, and an
openlook frontend called bibcard.

There's also tib, I don't use this, but I understand it's more
flexible.  It can be used with non-TeX text processing systems (i.e.
scribe).

I don't know of any commerical packages.

dave stephens

----

From: rodgers@maxwell.mmwb.ucsf.edu (R. P. C. Rodgers, M.D.)


Steven,

One system you will want to know about is bibIX.  Although the current
production release is tied to troff, we have a formatter-independent version
in the works, and a prototyupe is working with Frame, for example.

Cheerio, Rick Rodgers
********************************************************************************
*
*                               ANNOUNCEMENT
*
*  PROGRAM PACKAGE:  BibIX Bibliographic Database and Text Format