From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!uwm.edu!rutgers!mcclb0.med.nyu.edu!sci.wfeb.edu!macrides
From: macrides@sci.wfeb.edu
Newsgroups: bionet.software
Subject: Re: bionet.miscellaneous
Message-ID: <1993Apr1.120000.107@wfeb2>
Date: 1 Apr 93 16:00:00 GMT
References: <darrenp.733377699@dibbler.cs.monash.edu.au> <1993Mar29.085959.18390@comp.bioz.unibas.ch>
Organization: Worcester Fndn. for Exptl. Biol.
Lines: 37

In article <1993Mar29.085959.18390@comp.bioz.unibas.ch>, doelz@comp.bioz.unibas.ch (Reinhard Doelz) writes:
>[...]
> I agree that it would be good to have a better 'sorted' environment. 
> In particular, the following interest groups could be valuable if 
> we can only afford running them :
> 
> bionet.software.avail		- those for asking for and discussing
>                                                availability, 
>                                   as well as announcing software
>                                   * MODERATED * 
> bionet.software.system          - general inquiries how to manage 
>                                                biocomputing sw
> 
> bionet.software.misc            - all other stuff not fitting to the
>                                      other bionet.software newsgroups. 
> 
> 
> In particular, a group which discusses availability issues is most 
> needed in my view, and should be moderated. If this thread gets enough 
> discussion we could dare to raise a call for discussion on it. 
>[...]

	I don't think there's a serious problem w.r.t. volume or junk for
those accessing bionet.software via news readers, but I suspect those with
email subsciptions, and those who check this group primarily for announcements
of software releases and upgrades, would greatly appreciate the creation of a
bionet.software.avail and corresponding email list.

	Hopefully, it would become the place where all of the biology-related
software archives and software developers post announcements of new software
or upgrades.
				Fote

=========================================================================
 Foteos Macrides           Worcester Foundation for Experimental Biology
 MACRIDES@SCI.WFEB.EDU     222 Maple Avenue, Shrewsbury, MA 01545
=========================================================================

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!comp.bioz.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: Molbio Software Standard
Message-ID: <1993Apr2.081120.23403@comp.bioz.unibas.ch>
Date: 2 Apr 93 08:11:20 GMT
References: <1993Apr1.215716.5202@gserv1.dl.ac.uk>
Sender: usenet@comp.bioz.unibas.ch (NEWS transaction account)
Reply-To: doelz@urz.unibas.ch
Distribution: bionet
Organization: EMBnet Switzerland [BASEL]
Lines: 78
Nntp-Posting-Host: biox.embnet.unibas.ch

In article <1993Apr1.215716.5202@gserv1.dl.ac.uk>, r.nakisa@ic.ac.uk ((Ramin Charles Nakisa) ramin) writes:

|> 
|> Here is an outline to discuss:
|> 
|> * The source is written in C.  C really is very portable and as an added
|>   bonus it allows us to use Don Gilbert's amazing ureadseq module to
|>   read and write sequences in all the standard formats.  This would also
|>   allow us to build up a standard library of functions, so that we don't
|>   have to re-invent the wheel with every program.

say _ANSI C_ and POSIX system calls. Never use dedicated tricks like 
memory mapping, byte-order dependent routines, and system-specific binary
data setups. 
|> 
|> * It should work when compiled for MS-DOS, Windows (quickwin), Macintosh
|>   (simple window format?), UNIX and X.
|> 
quite ambitious. You MUST include a text interface, and I would also 
want to have the VMS operating system in there. It would be great if
people would read a style guide to avoid spagetti code. An API below 
the UI needs to be defined and then you can put all you want on top. 

|> * It must be able to read and write all the standard sequence formats.
|> 
Why? A reasonabpe input API is sufficient to have all sequences imported
easily. Think about future sequence formats, which would need to be read 
also. 


|> * There should be a standard interface.  The most portable interface is
|>   one that consists of only printf and scanf.  A standard graphic
|>   interface would be very difficult to define in a platform-independent
|>   way.  Compiler's can usually produce basic windows for windowing
|>   operating systems eg. the quickwin library on the MS C/C++ 7.0 compiler.
|> 
Hoppla. You're putting things upside down if you were talking windows 
up in the definition. A reasonable API with structures defined for 
parameter transmission to the code can well live with complex I/O statements
if it is only modular enough. 

|> * It should offer sensible default parameters when possible, and
|>   use standard command-line switches.
|>
How to use these on a Mac?  :-) 
 
|> * Graphic output should be in at least two formats: Postscript and HPGL
|> 
Again, if a meta language can be agreed on, the output is only a driver
which needs to be plugged in. Make sure that the API on the output side is 
defined and it isn't a problem no longer.

|> * All source should be included and beautified.
|> 
|> 
This might kill you. Who is really interested in getting source? If it works,
it's fine. No need to fiddle with the compilesr of bersion X.Y.Z, patchlevel
1425 (but make sure that you have the XXX product disbled). Copyright 
procedures become significantly more important, and if there is a reasobable
object library (so that you can link to) I would be satisfied. 

|> If you have ever used particularly good/bad molbio software then here is
|> your chance to have a say before it's written!

You have forgotten the networks. The furure will be much more client/server
computing than you can currently imagine. 



-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |
|   Klingelbergstrasse 70          | FAX     x41 61 261- 6760 or 267- 2078     
|     CH 4056 Basel                | TEL     x41 61 267- 2076 or 2247    |   
+------------- bioftp.unibas.ch is the SWISS EMBnet node ----------------+
               -----------------------------------------

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!perrier!sundvall
From: sundvall@perrier.embnet.se (Mats Sundvall)
Newsgroups: bionet.software
Subject: Re: The Entrez CD-ROM and the Government Pr
Message-ID: <1ph8u9INNp15@buzz.bmc.uu.se>
Date: 2 Apr 93 11:44:09 GMT
References: <rhughes.42.0@ucsd.edu>
Reply-To: sundvall@perrier.embnet.se
Organization: EMBNet Project Sweden
Lines: 11
NNTP-Posting-Host: perrier.embnet.se

>It turns out that the staff at NCBI are totally unlike those at the GPO.  I 
>received an e-mail response to the above net message from Dennis at NCBI the 
>same day.  Next morning, Rose Marie called and this morning I received a 
>Fed Ex package containing a copy of Entrez.  Wow!  Thanks guys.

So, whats the deal for the rest of us? We did send a check a long time ago. We
have just seen the little note that told us to wait. How long? 

Mats Sundvall
University of Uppsala
Sweden

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!comp.bioz.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: Massively Parallel Applications in Sequence Analysis
Message-ID: <1993Apr2.075945.22969@comp.bioz.unibas.ch>
Date: 2 Apr 93 07:59:45 GMT
References: <1p6q49INNe18@s-crim1.dl.ac.uk> <C4novr.Knt@murdoch.acc.Virginia.EDU> <CMM.0.90.2.733655047.geirha@maud.ifi.uio.no> <1peuciINNicd@s-crim1.dl.ac.uk>
Sender: usenet@comp.bioz.unibas.ch (NEWS transaction account)
Reply-To: doelz@urz.unibas.ch
Distribution: bionet
Organization: EMBnet Switzerland [BASEL]
Lines: 49
Nntp-Posting-Host: biox.embnet.unibas.ch

In article <1peuciINNicd@s-crim1.dl.ac.uk>, mbpcr@s-crim1.dl.ac.uk (A. Parsons) writes:
|> The question I originally asked also had the caveat (which noone to date has
|> commented on) "How much longer can we do WITHOUT data parallel solutions for
|> searching the masses of data being generated by the HGMP?"
|> 

Sorry for playing devil's advocate but I would say that the individual 
site can live long without a parallel computer. The database providers 
might like to have one, which they can use effectively. The biocomputer
sites might need one (if they can afford to abandon the safe tracks and 
develop, maintain, and optimize own hardware/software solutions). 

You might have seen the discussion on the suspected contaminations reported
in human cDNA libraries (Science, issue of previous week). In order to run 
thousands of sequences vs. EMBl, SWISSPROT, GENBANK, PIR we used a Silicon 
Graphics Cluster, containing 2 Indigos, a Crimson, and a 2-Processor Power 
series. It took about two to three weeks elapsed time on this setup, where
the machines were also used for development work, molecular modelling, and 
general GCG usage. Now if you have such a problem of running 10000 fasta 
and blast jobs, how often do you need the results `yesterday` ? How often do 
you have these giantic questions at all? If you run these analysis, the 
'granularity' as given in the fact that you run each sequence after another 
is sufficient to dissipate it amongst machines. You might want to have a 
parallel version if you have a multi-processor machine but the real idea 
is that the effort to manage, and maintain, a pvm installation is tedious 
on the long run. A Hierarchical Access System is perfect enough - you 
distribute single jobs across the net and keep using the 'established' 
software. This is alos beneficious due to the fact that the experience 
with the parameters and the search results is generally higher with fasta
or blast-type of searches than with special algorithms. 

Last point coming into mind is that the question on 'similarity' is 
differently asked at database providers rather than end users. A reasona-
ble check of a database annotator is to look for identities, maybe figure 
out alleles, but not weak homologies as most of the end users are interes-
ted in. This is explicitly not talking on the 'biocomputers' who search 
the needle in the hey (no pun intended - just to scale the effort right). 
Those guys might not be able to live without monsters in the future. 


-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |
|   Klingelbergstrasse 70          | FAX     x41 61 261- 6760 or 267- 2078     
|     CH 4056 Basel                | TEL     x41 61 267- 2076 or 2247    |   
+------------- bioftp.unibas.ch is the SWISS EMBnet node ----------------+
               -----------------------------------------

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: Rob.Harper@csc.fi (Rob Harper)
Newsgroups: bionet.software
Subject: Simtel20 uploads for March
Message-ID: <1993Apr2.081940.11541@gserv1.dl.ac.uk>
Date: 2 Apr 93 08:19:46 GMT
Sender: harper@fi.csc
Distribution: bionet
Lines: 474
Original-To: bio-soft@uk.ac.daresbury

File PD1:<MSDOS.FILEDOCS>UPLOADS.MAR                 Created: Apr. 1, 1993

NOTE: This file is also available in comma-delimited format as SIM9303.IDX

           MSDOS FILES UPLOADED TO WSMR-SIMTEL20.ARMY.MIL
                   during the month of March 1993

NOTE: Type B is Binary; Type A is ASCII

 Filename   Type Length   Date    Description
==============================================
Directory PD1:<MSDOS.4DOS>
4DMK402.ZIP   B   11650  930331  Update file for 4DOS 4.01 utility disk users
4DOS402D.ZIP  B  262145  930331  Manual for 4DOS 4.02 COMMAND.COM replacement
4DOS402P.ZIP  B  310863  930331  4DOS 4.02 Programs and auxiliary files
4DOS402U.ZIP  B  175545  930331  4DOS 4.02 update for registered 4.01d users
4DUPD402.ZIP  B    7562  930331  List of what's new in 4DOS 4.02
4SIGHT13.ZIP  B    7314  930304  tcsh-like & windowed 4DOS filename completion

Directory PD1:<MSDOS.ARCUTILS>
AM91.ZIP      B  222157  930322  ArcMaster front-end/convrt for ARC/ARJ/LZH/ZIP
ARCID102.ZIP  B   19962  930314  Identifies archive types by file signature
AT780D.ZIP    B  109719  930322  Archive shell for ARC/LZH/PAK/PKA/LBR/ZOO/ZIP
RV249.ZIP     B   27151  930322  Archive lister for ZIP/ARJ/LZH/ZOO/PAK/ARC etc
RVS110.ZIP    B   50642  930322  RVS-RView: View/extract contents of archives
SHEZ89.ZIP    B  224529  930318  Shell interface to ZIP/ARJ/LZH/ZOO/ARC/SQZ/PAK

Directory PD1:<MSDOS.ASMUTL>
80X0393.ZIP   B  172490  930328  ASM snippet collection from 80XXX FidoNet echo
TBONES07.ZIP  B   37888  930305  Skeletal ASM programs for programming TSRs

Directory PD1:<MSDOS.ASTRONOMY>
AA-51.ZIP     B  167571  930320  Astronomical almanac - sun moon planets stars
DE118I.ZIP    B  185587  930320  N-body numerical integration of moon & planets
SKYIMG1.ZIP   B 1048378  930306  Planetary/Lunar GIF images for SkyMap v1.2
SKYMAP12.ZIP  B  244063  930306  SkyMap v1.2 Win3.1 Planetarium program+docs

Directory PD1:<MSDOS.AUTOCAD>
GEOTOL.ZIP    B   31420  930308  GD&T made easy for AutoCAD R12

Directory PD1:<MSDOS.BATUTL>
MS-ASK.ZIP    B    3428  930303  Ask user for input in a batch file. w/ASM src
TSBAT42.ZIP   B  100448  930302  Collection of useful batch files by Timo Salmi
WAITER.ZIP    B   11459  930306  Batutl: Counts down, allowing user to bail out

Directory PD1:<MSDOS.BBS>
FMQT131U.ZIP  B   52695  930315  Quoter for 'FM' BBS FrontDoor Message Editor
GCHAT140.ZIP  B   35679  930318  Generic BBS Chat v1.40. DESQview aware, free
PCBEM103.ZIP  B   35143  930322  Multiple event manager for PCBoard BBS
WCAT26A.ZIP   B  445278  930317  Working demo of Wildcat BBS, part A. 921103
WCAT26B.ZIP   B  360679  930317  Working demo of Wildcat BBS, part B. 921103

Directory PD1:<MSDOS.BBSDOORS>
BID200.ZIP    B   56806  930318  BBS Information Door v2.00 new user help

Directory PD1:<MSDOS.BIBLE>
VIDBOOK0.ZIP  B 1604730  930325  Graphic GIFs&viewer Bible Study - Romans 1:20
VIDBOOK1.ZIP  B 1783585  930325  Graphic GIFs&viewer Bible Study - Isaiah 30:26

Directory PD1:<MSDOS.BINEDIT>
BVIEW1_0.ZIP  B   46621  930325  BView v1.0: Binary or hex file viewer/editor

Directory PD1:<MSDOS.BOOTUTIL>
MNUBT300.ZIP  B   36494  930305  Select from multi configs w/booting, (VGA req)

Directory PD1:<MSDOS.C>
ACTLIB11.ZIP  B  150258  930302  General purpose libraries C/C++ programmers
LINGU11A.ZIP  B   28031  930317  Easy multi-language support for C programs
ODOORS41.ZIP  B  424685  930318  C library for creating professional BBS doors
PCL4C34.ZIP   B   71564  930322  Asynchronous communications library for C

Directory PD1:<MSDOS.CAD>
BCAD100.ZIP   B  315374  930319  BCAD v1.0 CAD/CAM editor, VGA/286/386/486
EASYTRAX.ZIP  B  496079  930318  Protel's powerful PCB layout, freeware version
LASI411A.ZIP  B  302597  930318  LASI v4.11 IC layout CAD prgm: unzip in \lasi4
LASI411B.ZIP  B  331388  930318  LASI v4.11 IC layout CAD prgm: unzip in \lasi4
LASI411C.ZIP  B  279701  930318  LASI v4.11 IC layout CAD prgm: unzip in \lasi4
LASIDEMO.ZIP  B   22424  930318  LASI v4.1 DEMO drawing: unzip in \lasi4\demo
TMC101.ZIP    B  138128  930331  TextModeCad: CAD system in text mode envirnmnt

Directory PD1:<MSDOS.CALCULATOR>
RSC300.ZIP    B   65164  930301  Resident Scientific Expression Calculator v3.0

Directory PD1:<MSDOS.CHEMISTRY>
TORG311.ZIP   B  174878  930329  Organic chemistry ID of unknowns simulator

Directory PD1:<MSDOS.CLIPPER>
CLTAB100.ZIP  B    7031  930304  Align your Clipper (Summer/5.0) programs
CL_CLK10.ZIP  B    6447  930325  Clock for Clipper 5.0, with Clipper source
NFLIB21.ZIP   B  208840  930325  Nanforum Toolkit v2.1, docs/library/NG, 1/2
NFSRC21.ZIP   B  361267  930325  Nanforum Toolkit v2.1, src code/Make file, 2/2

Directory PD1:<MSDOS.COMPRESS>
GZIP107.ZIP   B   49053  930322  GNUzip: Unix compress/uncompress replacement

Directory PD1:<MSDOS.CPLUSPLUS>
TSR100JE.ZIP  B   75319  930324  TSR class for Borland C++ (with source)

Directory PD1:<MSDOS.DATABASE>
CDS300D.ZIP   B   57902  930321  CD Catalog with browse & search. Mouse Support
CEM063.ZIP    B  218777  930310  Records cemetery tombstone inscriptions
CEQPT37B.ZIP  B  165371  930323  Database for equipment service/usage histories
CINVT55C.ZIP  B  164615  930323  Inventory pgm for tracking store stock/orders
COLLCT21.ZIP  B  369801  930326  CollectorMate v2.1: Database for collectors
TCARD28.ZIP   B  268321  930301  Small business employee punch card. Log in/out
TIMTBL01.ZIP  B  186429  930325  Timetable printer saves data to Paradox tables

Directory PD1:<MSDOS.DDJMAG>
DDJ9211.ZIP   B  991669  930303  Dr. Dobbs Journal mag listings, Nov. 1992

Directory PD1:<MSDOS.DEMACS>
DEM-FAQ.ZIP   B   12755  930305  Frequently Asked Questions for Demacs

Directory PD1:<MSDOS.DIRUTL>
CSAP312.ZIP   B   31639  930322  Sorts disk directory, removes deleted entries
FFF42.ZIP     B  118886  930318  Derr's FileFinder 4.2, performs fuzzy search

Directory PD1:<MSDOS.DSKUTL>
DCF40F.ZIP    B   67511  930314  Very fast 1-pass diskette copy utility
FLEXP250.ZIP  B  189086  930331  Flexibak Plus: Hard disk backup w/compression
KG_DF105.ZIP  B    5291  930316  Disk Free: Disk free/used as % of total, w/src
MACSEE22.ZIP  B   54701  930325  Read/write Macintosh disks on PC. DOS & WIN3.x
TCPY200.ZIP   B   54509  930325  Fast multi-volume file copy program
WDATIDE.ZIP   B  122573  930317  Western Digital hard disk utility, from WD BBS

Directory PD1:<MSDOS.DV-X>
DESKU110.ZIP  B  234104  930322  File, font, mouse and more utilities for DV/X

Directory PD1:<MSDOS.EDITOR>
BOXER50A.ZIP  B  296096  930302  Boxer5.0a Editor:mouse,undo,mult files&windows
SEDIT100.ZIP  B  319647  930314  Easy to use text editor with spelling check
TMED160A.ZIP  B    9672  930331  Small TSR memory editor and key macro
VDE165A.ZIP   B  152333  930321  Meyer's small, fast, WordStar-like text editor

Directory PD1:<MSDOS.EDUCATION>
ACLOCKMP.ZIP  B  363411  930315  Animated Clock: Teach kids to tell time
AMDCM1A.ZIP   B  226417  930315  Animated multiplication/division game, 1 of 2
AMDCM1B.ZIP   B  407270  930315  Animated multiplication/division game, 2 of 2
AMEM20.ZIP    B  266091  930315  Animated Memory Game: aids kids' memory skills

Directory PD1:<MSDOS.ELECTRICAL>
DAUBWAVE.ZIP  B   45610  930303  Wavelet analysis program, w/C source

Directory PD1:<MSDOS.FILEDOCS>
AUTFTP12.ZIP  B   18779  930306  Auto get files from OAK using SIMDIR+NSCA FTP
CDROM.INF     A     806  930327  Where to obtain SIMTEL20 files on CD-ROM
CHANGES.DOC   A    1156  930329  Details on SIMTEL20's change to ZIP 2.0 format
DOWNLOAD.INF  A    2829  930327  How to get SIMTEL20 files via telephone modem
MAILSERV.INF  A    3119  930322  List of e-mail servers offering SIMTEL20 files
OAKFTP01.ZIP  B    2544  930331  Unix script to auto-ftp MS-DOS files from OAK
QUICKREF.LST  A    3901  930331  Quick reference list to SIMTEL20's MSDOS dirs
SIMIBM.HDR    A     815  930327  SIMIBM.IDX header file for PC-File+ use
SIMIBM.ZIP    B  299379  930331  Comma-delim list of all MSDOS files w/descrip.
SIMLIST.ZIP   B  292846  930331  Text format list of all MSDOS files w/descrip.

Directory PD1:<MSDOS.FILUTL>
DLCPMV23.ZIP  B   26067  930323  BSD Unix-style file copying/moving utilities
EXECUT10.ZIP  B    8140  930325  Archive files with common extentions. (w/src)
HFM318.ZIP    B  342215  930318  Filemanager/archive shell,compares 2 dir lists
UUDO12.ZIP    B   19370  930331  Multi-file/multi-part 'smart' uudecoder
UUEXE521.ZIP  B   33438  930315  R.E. Marks' fast multi-section UU/XX EN/DEcode

Directory PD1:<MSDOS.FINANCE>
DEBTFR30.ZIP  B  194655  930326  Home mortgage mgr, calculate/record payments
STCKT700.ZIP  B  370442  930318  Stock Trader v7.00: Stock history, buy, sell

Directory PD1:<MSDOS.FOODS>
MCHEF_1A.ZIP  B  279829  930309  Recipe, diet & meal management tool. Part 1of2
MCHEF_1B.ZIP  B  307611  930309  Recipe, diet & meal management tool. Part 2of2

Directory PD1:<MSDOS.GENIE>
ILMP9303.ZIP  B   78100  930307  GEnieLamp IBM Online Magazine (Mar 1993)

Directory PD1:<MSDOS.GIF>
VPIC60.ZIP    B  248433  930322  GIF/MAC/PCX/ColorRix pics view/convrt, EGA/VGA

Directory PD1:<MSDOS.GNUISH>
RCS55AS.ZIP   B  201450  930331  Revision Control System for text files, source
RCS55AX.ZIP   B  193001  930331  Revision Control System for text files EXE/doc

Directory PD1:<MSDOS.GRAPH>
GRPHCA22.ZIP  B  256733  930309  Interactive scientific plotting program, v2.2

Directory PD1:<MSDOS.GRAPHICS>
CBOOK.ZIP     B  159565  930331  Holloway's VGA+mouse coloring book for kids
CHIARO10.ZIP  B  127870  930319  Chiaro Suite of image utilities release 1.0
DISP125.ZIP   B  266563  930329  Display/convert images with different formats
MAKAMESS.ZIP  B  445810  930331  VGA graphical message maker/presenter. Req 386
SVGAKT31.ZIP  B  318358  930307  SuperVGA test kit lib. Supports most SuperVGAs
UVESA31.ZIP   B   21525  930307  Universal VESA TSR for most SuperVGA cards

Directory PD1:<MSDOS.HAMRADIO>
FRGLOD10.ZIP  B   14327  930329  Hams: Yaesu FRG100 sw-rcvr channel data progmr
JVFAX51.ZIP   B  318153  930304  Ham Radio FAX and SSTV program version 5.1

Directory PD1:<MSDOS.HYPERTEXT>
DART1G.ZIP    B  230550  930303  Hypertext file viewer and launcher, w/editor
HLPDK21.ZIP   B  251303  930329  DOS/Windows hypertext Help development kit

Directory PD1:<MSDOS.INFO>
ASP6302.ZIP   B  532493  930315  Association of Shareware Professionals catalog
FAQP9305.ZIP  B   49813  930317  comp.os.msdos.programmer FAQ from Usenet
FTPLIST.ZIP   B   6880
From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!darwin.sura.net!news-feed-1.peachnet.edu!umn.edu!msus1.msus.edu!TIGGER.STCLOUD.MSUS.EDU!Q00023
From: q00023@TIGGER.STCLOUD.MSUS.EDU
Newsgroups: bionet.software
Subject: Hydrophobicity of amino acid chain determination
Message-ID: <1993Apr1.221826.2929@msus1.msus.edu>
Date: 2 Apr 93 04:18:26 GMT
Reply-To: q00023@TIGGER.STCLOUD.MSUS.EDU
Organization: ST. CLOUD STATE UNIVERSITY, ST. CLOUD, MN
Lines: 8
Nntp-Posting-Host: tigger.stcloud.msus.edu

Dear netters,
	I would like to know if there are any shareware of determining hydrophobicity of a amino acid chain. I would appreciate anyone who reply to my request.

Thanks in advance,

Gabriel Cheung
St.Cloud State University
Biotechnology & Biochemistry

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!LAKE.SCAR.UTORONTO.CA!chan
From: chan@LAKE.SCAR.UTORONTO.CA (Leslie Chan)
Newsgroups: bionet.software
Subject: reading Postscript file
Message-ID: <9304020242.AA08898@lake.scar.utoronto.ca>
Date: 2 Apr 93 02:42:52 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 8

Hello all,
I downloaded why I thought was a plain text file via anonymous FTP but
it turned out to be a postscript file. I use Word on a Macintosh but I
can't seem to convert the file to readable form. Any suggestions would
be greatly appreciated.

Leslie Chan
Chan@lake.scar.utoronto.ca

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: free or cheap homology programs
Message-ID: <1993Apr2.165452.8767@welchgate.welch.jhu.edu>
Date: 2 Apr 93 16:54:52 GMT
References: <1pe5u4INNbe5@uniwa.uwa.edu.au>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 23

In article <1pe5u4INNbe5@uniwa.uwa.edu.au> robert@arbo.microbiol.uwa.oz.au (Robert Coelen) writes:
>
>
>Hi,
>
>Can anyone tell me which of the major Nucleic Acid database
>interrogation programs, available for Unix boxes, are FOC or relatively
>cheap for a university environment ??
>
>

FastA and Blast are two of the more common ones - both are available for
free by anonymous ftp.

FastA from virginia.edu in the pub/fasta/ directory.

Blast from ncbi.nlm.nih.gov in the pub/blast directory.

Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!agate!usenet.ins.cwru.edu!gatech!usenet.ufl.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: DNA analysis software for Macintosh
Message-ID: <1993Apr2.164849.8015@welchgate.welch.jhu.edu>
Date: 2 Apr 93 16:48:49 GMT
References: <1993Mar31.144114.3097@ucbeh.san.uc.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 42

In article <1993Mar31.144114.3097@ucbeh.san.uc.edu> craftdl@ucbeh.san.uc.edu writes:
>I am in need of an inexpensive DNA analysis software program for the Macintosh.
>The program should be able to do sequence comparisons, restriction enzyme
>analysis, translations, etc. I realize there are excellent programs available
>for the Macintosh;however, graduate students on a limited budget cannot afford
>these expensive programs. This problem is compounded when your department is
>basically PC oriented and cannot purchase a program for the Mac. If anyone has
>suggestions or knows of inexpensive programs, please mail me at
>CRAFTDL@ucbeh.san.uc.edu  

Sounds like what you're looking for is Don Gilbert's SeqApp - available
by gopher or anonymous ftp at ftp.bio.indiana.edu - a little clip from
the readme is as follows:

SeqApp is a biological sequence editor and analysis program for
Macintosh computers.  It includes links to network services and 
external analysis programs.

Features include	
	multiple sequence alignment editor
	single sequence editor window
	read and write several sequence file formats
	easy hand alignment features including colored bases and sliding
	automatic multiple sequence alignment thru Clustal external app 
	automatic gel fragment alignment to contigs thru exernal app
	consensus,reverse,complement,degap operations
	restriction maps
	dot plots
	translate dna to/from protein using various codon tables
	automatic preference saving
	internet send mail, read mail
	internet gopher, information retreival including genbank.
	internet sequence analysis services
	user-definable links to external analysis programs
	and more


Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!agate!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software
Subject: Re: Molbio Software Standard
Message-ID: <1pggn0$amq@overload.lbl.gov>
Date: 2 Apr 93 04:50:40 GMT
References: <1993Apr1.215716.5202@gserv1.dl.ac.uk> <1993Apr1.223703.13177@alw.nih.gov>
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 25
NNTP-Posting-Host: s27w007.pswfs.gov

Go for it guys.  While you biologists are standardizing and writing
the software standard we programmers will be standardizing the meaning
of locus, gene, allele, wild-type, species, homology, germplasm, site,
map, mutation, pathogen and trait.  Then we will tell you the common
format for segregation data that is self-descriptive with regard to
the pedigree, type of cross, and ploidy.  Next we will tell you how
to name your probes and libraries.

By that time you should just about have come to terms with small, medium,
huge and obese memory models for MessyDos, resource forks in Macs, record
types in VMS, concurrent record updates, non-deterministic operating
systems and the deadly embrace.

If you guys keep thinking of programmers as lab techs we're not going
to get anywhere.

    Captiously,
    --bks


-- 
Bradley K. Sherman, Dendrome Project
Institute of Forest Genetics, USDA Forest Service
P.O. Box 245, Berkeley, CA, 94701, USA
Phone: 510-559-6437   FAX: -6440 Internet: bks@s27w007.pswfs.gov

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!UM.CC.UMICH.EDU!Doug.Eernisse
From: Doug.Eernisse@UM.CC.UMICH.EDU
Newsgroups: bionet.software
Subject: Cladistics Programs for Dos/Unix?
Message-ID: <21617704@um.cc.umich.edu>
Date: 2 Apr 93 16:01:08 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 33

Just to clarify Carol Bult's recent comments:
> The DOS-based cladistics program I use is Hennig86 which was written
> by Steve Farris. The program cost is modest, ~ $50.00 (U.S.), but I'm not
>-sure how
> Steve is handling the distribution of the program because he no longer
> lives in the US.
 
Hennig86 is obtained by sending a check to:
 Dr. A. Kluge
 Museum of Zoology
 Univ. of Michigan
 Ann Arbor, MI 48109
 
Cost is $50 plus $5 or $10 for shipping and diskette, etc., 
depending on whether the order is from U.S. or not, respectively.
 
>My understanding is that he is working on a
> Windows version of PAUP, but it will probably be awhile before that is
> ready for distribution.
 
The non-Mac version of PAUP, which might be released soon or perhaps
not, does not depend on Windows. The Mac version 3.1 will soon be
released. The old MS-DOS/mainframe version is truly obsolete and
should not be used (unless you don't care whether or not you find
the minimum length trees).
 
As Carol mentioned, Phylip is available and is free (Joe, have you
got it working on microwave ovens yet? ;-)
 --virtually all platforms--does other things besides parsimony
searches
 
Doug Eernisse
Doug_Ee@um.cc.umich.edu

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!BENGAL.TIGR.ORG!bult
From: bult@BENGAL.TIGR.ORG (Carol Bult)
Newsgroups: bionet.software
Subject: Cladistics Programs for Dos/Unix?
Message-ID: <9304021419.AA03907@bengal.tigr.org>
Date: 2 Apr 93 14:19:25 GMT
References: <9304012321.AA21694@net.bio.net>
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 58


Rober Guralnick asked about cladistic analysis programs for DOS/Win or
UNIX.

The DOS-based cladistics program I use is Hennig86 which was written
by Steve Farris. The program cost is modest, ~ $50.00 (U.S.), but I'm not sure how
Steve is handling the distribution of the program because he no longer
lives in the US. He is working on a new version which I think he plans
on releasing this summer at the Hennig Meetings (August 9-13,
Fullerton, CA.).

Kevin Nixon (Cornell University) has written a program called CLADOS which is
file compatible with Hennig86. I haven't used the program yet, so I'm
not sure what its capabilities are. You might want to contact Keven to
find out more about his program: 

Dr. Kevin C. Nixon
LH Bailey Hortorium
Cornell, University
Ithaca, NY 14853

Again, the cost is modest (last I heard, it was $50).


There is an old, old DOS version of PAUP (Phylogenetic Analysis Using
Parsimony, by David Swofford), but I'm not even sure if David
distributes it anymore. My understanding is that he is working on a
Windows version of PAUP, but it will probably be awhile before that is
ready for distribution.


Joe Felsenstein distributes the C source code for his program, PHYLIP,
via anonymous FTP. He just released version 3.5. It's free and can run
on 386 or 486 PCs or UNIX. The FTP site is:

evolution.genetics.washington.edu (IP 128.95.12.41)

If you can't access the files via FTP, you can send him several diskettes (call him first
to find out how many you would need to send) and he'll send you the
program that way.  Joe's address is:

		Dr. Joe Felsenstein
		Dept. of Genetics
		Univ of Washington
		Seattle, WA 98195

Good luck..

Carol

___________________________________________________________________
Carol Bult, Ph.D.			bult@tigr.org                               
The Institute for Genomic Research
932 Clopper Road			voice: 301-869-9056
Gaithersburg, MD 20878			fax:   301-869-9423

___________________________________________________________________


From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: Cladistics Programs for Dos/Unix?
Message-ID: <1993Apr2.170342.9976@welchgate.welch.jhu.edu>
Date: 2 Apr 93 17:03:42 GMT
References: <1pftdd$l30@agate.berkeley.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 25

In article <1pftdd$l30@agate.berkeley.edu> robg@fossil.Berkeley.EDU (Robert Guralnick) writes:
>Hi all -
>
>	Quick question... Any decent relatively inexpensive or free (!!!!)
>cladistic analysis program out there for either DOS/Win3.1 or Unix based
>environments.  Thanks. 
>

Joe Felsenstein's PHYLIP is a *very* extensive phylogeny package with
versions for Unix, VMS, DOS, Mac ...  PHYLIP comes with *lots* of
documentation and is all available for free by anonymous ftp from
evolution.genetics.washington.edu in the pub/ directory.

The documentation also contains a list of other phylogeny packages available 
from others.

Paup, by David Swofford, is a good phylogeny package that costs about
$50.


Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!WSUVMS1.CSC.WSU.EDU!THOMPSON
From: THOMPSON@WSUVMS1.CSC.WSU.EDU (Steve Thompson: VADMS genetics)
Newsgroups: bionet.software
Subject: PostScript and Mac MS Word
Message-ID: <930402104012.20203d51@BOBCAT.CSC.WSU.EDU>
Date: 2 Apr 93 18:40:12 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 46

Hello Leslie and the rest of the bio-soft world -

Leslie Chan <chan@lake.scar.utoronto.ca> 
in message <9304020242.AA08898@lake.scar.utoronto.ca>

wrote:

>Hello all,
>I downloaded why {what} I thought was a plain text file via anonymous FTP but
>it turned out to be a postscript file. I use Word on a Macintosh but I
>can't seem to convert the file to readable form. Any suggestions would
>be greatly appreciated.
>
>Leslie Chan
>Chan@lake.scar.utoronto.ca

Using ONLY MS Word on a Mac, the only way that I know of {who knows how many
others there really are 8-)} to interpret actual postscript is by selecting ALL
of the PostScript text with your mouse and then using the Style options in one
of your menus {I'm sorry but I am not sitting at my Mac now so I can't describe
the actual menu entry names} such that the selected text is converted to Word's
special PostScript Style.  This converts it into a special reserved format
which Apple LaserWriters recognize as being true PostScript rather than just
ASCI.  Then print that file to your Laserwriter from within word.

Other ways which do not use Word include the Apple LaserWriter Utility which
can download ASCI PostScript files to a Laserwriter printer for interpretation
and the public domain package GhostScript which can allow onscreen previewing
of most PostScript files.  These topics have been covered several times within
this newgroup and summaries are available by Gopher through IUBIO.

What "I" would like to be able to figure out is how to accurately position and
rescale EPSF files within an MS WORD document.  It may not be possible but I
keep trying.  I know it should be possible within "fancier" layout and graphics
packages such as PageMaker and Canvas but my {and our program's} empty pockets
preclude that route. 
						G'day All, Steve T

                              Steven M. Thompson
            Consultant in Molecular Genetics and Sequence Analysis
VADMS (Visualization, Analysis & Design in the Molecular Sciences) Laboratory
           Washington State University, Pullman, WA 99164-1224, USA
          AT&Tnet:  (509) 335-0533 or 335-3179  FAX:  (509) 335-0540
                  BITnet:  THOMPSON@WSUVMS1 or STEVET@WSUVM1
                   INTERnet:  THOMPSON@wsuvms1.csc.wsu.edu


From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!LIBRARY.CATAWBA.EDU!scoggin
From: scoggin@LIBRARY.CATAWBA.EDU (Dr. Steve Coggin)
Newsgroups: bionet.software
Subject: (none)
Message-ID: <55677.scoggin@library.catawba.edu>
Date: 2 Apr 93 19:27:54 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 1

Subscribe bio-software Steve Coggin

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!agate!spool.mu.edu!uwm.edu!zaphod.mps.ohio-state.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: Hydrophobicity of amino acid chain determination
Message-ID: <1993Apr2.171833.11305@welchgate.welch.jhu.edu>
Date: 2 Apr 93 17:18:33 GMT
References: <1993Apr1.221826.2929@msus1.msus.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 19

In article <1993Apr1.221826.2929@msus1.msus.edu> q00023@TIGGER.STCLOUD.MSUS.EDU writes:
>Dear netters,
>	I would like to know if there are any shareware of determining hydrophobicity of a amino acid chain. I would appreciate anyone who reply to my request.
>

There are several available, any paricular machine/OS your looking for?

For DOS there's Prograph by (Kay Hofmann), and seqaid.  For the Mac
there's PLOTA .....

Prograph and PLOTA are available by gopher and anonymous ftp from 
(among others) felix.embl-heidelberg.de.  Seqaid is available by 
gopher and anonymous ftp from (among others) ftp.bio.indiana.edu.

Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Thu Apr 01 23:00:00 1993
Path: biosci!CU.NIH.GOV!CZJ
From: CZJ@CU.NIH.GOV
Newsgroups: bionet.software
Subject: Re:  Hydrophobicity of amino acid chain determination
Message-ID: <9304021657.AA00747@net.bio.net>
Date: 2 Apr 93 15:38:28 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 36

> MAIL VIA INTERNET FROM BIOSCI-REQUEST@net.bio.net  THURSDAY  04/01/93  11:21:34 P.M.
>
> Received: from CU.NIH.GOV by NIHCU (Mailer) id 1152;
>               Thu, 01 Apr 93  23:21:34 EST
> Received: from NET.BIO.NET by CU.NIH.GOV
>     with TCP; Thu, 1 Apr 93 23:22:59 EST
> Received: by net.bio.net (5.65/IG-2.0)
>        id AA06272; Thu, 1 Apr 93 20:23:27 -0800
> Received: by net.bio.net (5.65/IG-2.0)
>        id AA06268; Thu, 1 Apr 93 20:23:26 -0800
> Message-Id: <9304020423.AA06268@net.bio.net>
> To: bio-soft@net.bio.net
> From: q00023@TIGGER.STCLOUD.MSUS.EDU
> Subject: Hydrophobicity of amino acid chain determination
> Date: 2 Apr 93 04:18:26 GMT
> Reply-To: q00023@TIGGER.STCLOUD.MSUS.EDU
> Nntp-Posting-Host: tigger.stcloud.msus.edu
>
> Dear netters,
>        I would like to know if there are any shareware of determining hydrophobicity of a amino acid chain. I would appreciate anyone who reply to my request.
>
> Thanks in advance,
>
> Gabriel Cheung
> St.Cloud State University
> Biotechnology & Biochemistry
>
>

Profilegraph writen by Kay Hofman has that information in an easy to
use format.

It can be obtained fromt he embl file server and other ftp sites.

Jim Cassatt


From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!agate!spool.mu.edu!uunet!decwrl!concert!rock!taco!csemail.cropsci.ncsu.edu!samodena
From: samodena@csemail.cropsci.ncsu.edu (S. A. Modena)
Newsgroups: bionet.software
Subject: Re: The Entrez CD-ROM and the Government Printing Office (US)
Message-ID: <1993Apr2.224449.15497@ncsu.edu>
Date: 2 Apr 93 22:44:49 GMT
References: <rhughes.40.0@ucsd.edu>
Sender: news@ncsu.edu (USENET News System)
Organization: Crop Science Dept., NCSU, Raleigh, NC 27695-7620
Lines: 24

In article <rhughes.40.0@ucsd.edu> rhughes@ucsd.edu (Richard J. Hughes) writes:
>Has anyone else been having trouble ordering the Entrez CD-ROM from the US 
>Government Printing Office?  I have had plenty of difficulty.
>.....
>When you call the Gov't Printing Office, you are put on hold for a long 
>time. When someone finally answers, the audio is so faint as to be almost 
>indiscernable (maybe 5 dB above background).

Please post the GPO phone number: I want to take a crack at that system.
;^)

Steve
---
+------------------------------------------------------------------+
|     In person:  Steve Modena     AB4EL                           |
|     On phone:   (919) 515-5328                                   |
|     At e-mail:  nmodena@unity.ncsu.edu                           | 
|                 samodena@csemail.cropsci.ncsu.edu                |
|                 [ either email address is read each day ]        |
|     By snail:   Crop Sci Dept, Box 7620, NCSU, Raleigh, NC 27695 |
+------------------------------------------------------------------+
         Lighten UP!  It's just a computer doing that to you.    (c)
OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO
         

From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!swrinde!zaphod.mps.ohio-state.edu!wupost!spool.mu.edu!uunet!psinntp!newstand.syr.edu!SUVM.SYR.EDU!DRPORTER
From: DRPORTER@SUVM.SYR.EDU (Brad Porter)
Newsgroups: bionet.software
Subject: Population modeling software in the works...
Message-ID: <16BA412030.DRPORTER@SUVM.SYR.EDU>
Date: 3 Apr 93 01:46:15 GMT
Organization: Syracuse University
Lines: 15

This isn't an official announcement or anything, but I thought I'd inform
you of some biological software currently being developed.
   The project I'm currently working on is a matrix modeling program for
Windows 3.1.  While the project is still in the works, it will include
numerous graphical representations of the model, eigen value extraction,
and a variable projection matrix (complete with the ability to calculate
matrix values as functions of N).
   By posting this message, I'm really just trying to get a feel of how
many out there would be interested in the software when it's done.  The
package is scheduled to be in beta form by May.  Additional information
can be obtained by emailing either myself (I'm just the software engineer,
though), or Brian Underwood (the project director) at the addresses listed:
                 Dr. Brian Underwood:  deer@suvm.acs.syr.edu
                 Brad Porter:          drporter@suvm.acs.syr.edu
-Brad Porter

From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!howland.reston.ans.net!agate!overload.lbl.gov!bks
From: bks@s27w007.pswfs.gov (Bradley K. Sherman)
Newsgroups: bionet.software
Subject: Re: Molbio Software Standard
Message-ID: <1pl38j$9jh@overload.lbl.gov>
Date: 3 Apr 93 22:31:47 GMT
References: <1993Apr1.215716.5202@gserv1.dl.ac.uk> <1993Apr1.223703.13177@alw.nih.gov> <1pggn0$amq@overload.lbl.gov>
Organization: Dendrome, A Genome Database for Forest Trees
Lines: 32
NNTP-Posting-Host: s27w007.pswfs.gov

In article <1pggn0$amq@overload.lbl.gov> bks@s27w007.pswfs.gov (Bradley K. Sherman) writes:
> ...
>If you guys keep thinking of programmers as lab techs we're not going
>to get anywhere.
> ...

First of all, let me apologize for my intemperate remarks and
especially to lab techs without whom I could not do my work.

Writing software for researchers is a difficult proposition.
It is very common for a single successful run of a program
to be the last use of that program!  It is often the case that
a simple graph or picture is the culmination of hundreds of hours
of moving data from one form to another, filtering out
noise, and applying a special purpose mathematical transform
-- often some arcane algorithm thought up by Gauss after one
too many Schnapps on a chilly night in 1843 and never before
implemented in any form more concrete than a doctoral dissertation.

By the time the software is cast into a robust form, thoroughly
vetted and outfitted with its direct manipulation interface
for Curses, Windows , Windows NT, Mac, OS/2, OpenLook, NeXtStep
Motif, VMS, ... and then retested for window manager idiosyncrasies
the problem it solves may be of no interest.

    --bks

-- 
Bradley K. Sherman, Dendrome Project
Institute of Forest Genetics, USDA Forest Service
P.O. Box 245, Berkeley, CA, 94701, USA
Phone: 510-559-6437   FAX: -6440 Internet: bks@s27w007.pswfs.gov

From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!network.ucsd.edu!dialin1-32-1.extern.ucsd.edu!rhughes
From: rhughes@ucsd.edu (Richard J. Hughes)
Newsgroups: bionet.software
Subject: Re: The Entrez CD-ROM and the Government Printing Office (US)
Message-ID: <rhughes.13.733820204@ucsd.edu>
Date: 3 Apr 93 06:56:44 GMT
References: <rhughes.40.0@ucsd.edu> <1993Apr2.224449.15497@ncsu.edu>
Organization: ucsd.edu
Lines: 62
NNTP-Posting-Host: dialin1-32-1.extern.ucsd.edu

In article <1993Apr2.224449.15497@ncsu.edu> samodena@csemail.cropsci.ncsu.edu (S. A. Modena) writes:

>Please post the GPO phone number: I want to take a crack at that system.

Their voice phone number is (202) 783-3238, although this might not do you a 
whole lot of good.  This is what our secretary had to say:

-----------------------------Forwarded ----------------------------------
From: Andrina Marshall
Date: 3/29/93 4:45PM
To: Richard Hughes
Receipt Requested
Subject: Superintendent of Documents Fiasco
-------------------------------------------------------------------------
          Per your request please find below a brief description of
          this morning's events regarding my interaction with the
          vendor - Superintendent of Documents.

          I phoned the Superintendent of Documents this morning
          starting at 8AM, and after 5 or 6 attempts of busy signals
          finally got through and spoke to a TECHNICIAN.  After
          explaining to the TECHNICIAN that I spoke to a woman in the
          ORDERS DEPT. on March 18th asking her to send us an invoice
          for the subscription to Entry on CD-ROM because the
          university will not issue a check without an invoice, this
          TECHNICIAN said I should speak to the ORDERS DEPT. again.

          After being transferred to the ORDERS DEPT., I repeated the
          information adding that the woman said she would send out
          the invoice that day.  The ORDERS DEPT. representative then
          stated I should speak to CUSTOMER SERVICE.

          After being transferred to CUSTOMER SERVICE, I repeated the
          information and was told I should speak to the INVOICING
          DEPT.

          After being transferred to the INVOICING DEPT, I repeated
          the information and was told I should speak to a TECHNICIAN.

          I was then transferred back to the original gentleman I
          spoke with to begin with - the TECHNICIAN, and was told the
          invoice had PROBABLY been processed in their system but
          could take up to 3 or 4 weeks.  I stated that NOONE told
          this to me on March 18th, and that in fact the woman in the
          ORDERS DEPT. stated she would get the invoice out to me that
          day.  Last, I requested an invoice to be faxed, but was told
          "they don't do that anymore".


          I hope this helps.  GOOD LUCK.

-------------------------------------------------------------------------
Yes, you will need it.

Richard

+------------------------------------------------------------------------+
|  Dr. Richard J. Hughes                               rhughes@ucsd.edu  |
|  Department of Pharmacology                              <<KM6ED>>     |
|  University of California at San Diego              Tel (619) 534-2298 |
|  La Jolla,  CA 92093-0636                           FAX (619) 534-7461 |
+------------------------------------------------------------------------+

From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!agate!spool.mu.edu!uunet!mcsun!dxcern!hprd26a!tonko
From: tonko@hprd26a.cern.ch (Tonko Ljubicic)
Newsgroups: bionet.software
Subject: Free EMBL-database query/search software ?
Message-ID: <tonko.733842493@hprd26a>
Date: 3 Apr 93 13:08:13 GMT
Sender: news@dxcern.cern.ch (USENET News System)
Organization: CERN European Lab for Particle Physics
Lines: 12

Does anybody know of a free (or cheap) EMBL database searching
software ? In the manner of CD-SEQ from the EMBL CD for instance.
Preferably for DOS (Windows?) and Unix (X11?).

	-- Tonko


--
ljubicic@dxcern.cern.ch   ljubicic@cernvm.bitnet   tonko@hprd26a.cern.ch
Ante Tonko Ljubicic       Division PPE       
CERN                      (European Laboratory for Particle Physics)
1211 Geneve 23            Switzerland

From owner-software@net.bio.net Fri Apr 02 23:00:00 1993
Path: biosci!ICBR.IFAS.UFL.EDU!SJJ
From: SJJ@ICBR.IFAS.UFL.EDU ("JONG, SONG-MUH J")
Newsgroups: bionet.software
Subject: Re. EMBL File Server
Message-ID: <9304031516.AA25128@net.bio.net>
Date: 3 Apr 93 15:01:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 461

From: tonko@hprd26a.cern.ch (Tonko Ljubicic)
Subject: Free EMBL-database query/search software ?
Date: 3 Apr 93 13:08:13 GMT


tonko@hprd26a.cern.ch (Tonko Ljubicic) wrote:
>Does anybody know of a free (or cheap) EMBL database searching
>software ? In the manner of CD-SEQ from the EMBL CD for instance.
>Preferably for DOS (Windows?) and Unix (X11?).

Here is a newsletter from EMBL:

From: NETHELP@EMBL-Heidelberg.DE
Subject: EMBL File Server Newsletter No. 9, Dec. 4th 1992
Date: 4 Dec 92 11:03:17 GMT

------------------------------------------------------------------------------
|  EMBL FILE SERVER News                         Number 9, December 4th 1992 |
|                                                                            |
|  European Molecular Biology Laboratory, Data Library & Computer Group,     |
|  Postfach 10.2209, 6900 Heidelberg, Germany.                               |
|                                             Tel: +49 6221 387258           |
|  E-mail: NetHelp@EMBL-Heidelberg.DE         Fax: +49 6221 387519           |
------------------------------------------------------------------------------


Contents:

 <1> Introduction
 <2> Improvement of EMBL's Internet connectivity
 <3> Anonymous FTP services - alternative sites
 <4> New mail server command
 <5> Updates to data collections
 <6> Updates to software collection
 <7> Other updates
 <8> Summary of directories on the file server
 <9> Getting started ?
 <10> Network addresses at EMBL


<1> Introduction
    ------------

    The EMBL File Server is a facility available on the EMBL computing system
    for external users to request files by electronic mail, anonymous FTP or
    Gopher. The service is free.


<2> Improvement of EMBL's Internet connectivity
    -------------------------------------------

    Recently there has been a improvement in EMBL's Internet connection which
    results in considerably faster access to our anonymous FTP server and to
    our Gopher server, and also a quicker response to e-mail file server
    requests.

    Please note that the FTP and Gopher servers both run on 
                   FTP.EMBL-Heidelberg.DE  (192.54.41.33)
    Do not use the host name EMBL-Heidelberg.DE

<3> Anonymous FTP services - alternative sites

    (a) The anonymous FTP archives at EMBL are mirrored by an FTP server
        managed by the Israeli EMBnet national node (INN) at the Weizmann
        Institute.
        Internet address: sunbcd.weizmann.ac.il

    (b) Complete copies of the EMBL quarterly releases are also available
        by anonymous FTP from:
        - Swiss EMBnet Node, Biozentrum der Universitaet Basel (Switzerland) 
          Internet address: bioftp.unibas.ch [131.152.8.1]
          Maintained by Reinhard Doelz  (doelz@comp.bioz.unibas.ch)
          Plain ASCII flat files. See the file DESCRIPTION in the top level
          directory for more information, also on other formats of data.

        - Department of Molecular Biology Massachusetts General Hospital
          Internet address: amber.mgh.harvard.edu [132.183.190.26]
          Maintained by Mike Cherry (CHERRY@Frodo.MGH.Harvard.EDU)
          Compressed EMBL flat files. See the 000readme.txt file in the EMBL
          directory for more information, also on other formats of data. 


<4> New mail server command
    -----------------------

    The SIZE command was added to the set of commands recognised by the EMBL
    e-mail server. Because some mailer systems have a maximum file size
    limitation the EMBL mail server splits large files into parts. The default
    size of these packets is 95K but can be changed with the SIZE command.
    E.g. SIZE 30 would change the packet size to 30K, whereas SIZE 500 would
    set it to 500K. Note, however, that uuencoded files are stored in
    individual parts of 90K each on our server, so changing the packet size to
    larger values will have no effect on them.


<5> Updates to Data Collections
    ------------------------------------

    New databases have been added to the file server recently:

    (a) Steven Henikoff's BLOCKS database
        Henikoff, S. and Henikoff, J. G. (1991) Automated assembly of protein
        blocks for database searching. Nucleic Acids Res. 19, 6565-6572.
        E-mail server: directory BLOCKS
        Anonymous ftp: /pub/databases/blocks

    (b) A database of CpG islands in the human genome (CPGISLE)
        Larsen, F., Gundersen, G., Lopez, L. and Prydz, H. (1992) CpG island as
        Gene Markers in the Human Genome. Genomics 13, 1095-1107.
        E-mail server: directory CPGISLE
        Anonymous ftp: /pub/databases/cpgisle

    (c) A database of protein kinase catalytic domains (PKCDD)
        provided by S.K. Hanks, A.M. Quinn and T. Hunter, Salk Institute.
        E-mail server: directory PKCDD
        Anonymous ftp: /pub/databases/pkcdd

    (d) Pre-release data from the Brookhaven Protein Data Bank (PDB) are now
        available in addition to the full releases.
        E-mail server: directory PROTEINDATA


<6> Updates to Software Collection
    ------------------------------

    Here is a list of new (N) molecular biological programs or updates (U):
    The full path specifications for these files on the EMBL ftp server are
    shown in square brackets.

    DOS:
    ----

    AUTHORIN.UAA        (N) Sequence data submission tool
                            (Intelligenetics/DDBJ/EMBL/GenBank)
                            [/pub/software/dos/authorin.uaa to authorin.uaf]

    CODONS.UUE          (N) Codon usage analysis (A. Lloyd and P. Sharp)
                            [/pub/software/dos/codons.uue]

    CREGEX.C            (U) Conversion of PROSITE to Prosearch format v1.2
                            (J. Leunissen)
                            [/pub/software/dos/cregex.c]

    DOTPLOT.UUE         (N) Dot plot analysis (R> Nakisa)
                            [/pub/software/dos/dotplot.uue]

    ESEE.UAA            (U) Multiple sequence alignment editor v1.09e
                            (E. Cabot)
                            [/pub/software/dos/esee.uaa to esee.uac]

    FASTMAP.UAA         (N) Approx. multipoint lod score calculation
                            (D. Curtis)
                            [/pub/software/dos/fastmap.uaa to fastmap.uac]

    GEPASI.UAA          (N) Modelling of metabolic pathways (P. Mendes)
                            [/pub/software/dos/gepasi.uaa to gepasi.uai]

    MACAW105.UAA        (U) Multiple sequence editor v1.05 (G. Schuler)
                            [/pub/software/dos/macaw105.uaa and macaw105.uab]

    PEDRAW14.UAA        (U) Pedigree drawing program v1.4 (D. Curtis)
                            [/pub/software/dos/pedraw14.uaa to pedraw14.uae]

    RAMHA.UAA           (N) Monte Carlo simulation of random mutagenesis
                            synthetic cDNA (D. Siderovski)
                            [/pub/software/dos/ramha.uaa and ramha.uab]

    SAR2PCIT.UUE        (N) Conversion of SeqAnalRef to ProCite format
                            (E. Sonnhammer)
                            [/pub/software/dos/sar2pcit.uue]

    SORFIND.UAA         (N) Prediction of exons in vertebrate genomic DNA
                            (G. Hutchinson)
                            [/pub/software/dos/sorfind.uaa and sorfind.uab]

    TRBBS.UAA           (N) File exchange program for automated fluorescent DNA
                            sequencer data (I. Consani)
                            [/pub/software/dos/trbbs.uaa and trbbs.uab]
                            
    Mac:
    ----

    AUTHORIN.HQX        (N) Sequence data submission tool
                            (Intelligenetics/DDBJ/EMBL/GenBank)
                            [/pub/software/mac/authorin.hqx]

    DATAMINDER.HQX      (N) Data management tools for molecular biologists
                            (K. Usdin)
                          
From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!wupost!uunet!utcsri!utnut!torn!pulp.cs.laurentian.ca!abigail
From: abigail@ramsey.cs.laurentian.ca (Shawn Abigail)
Newsgroups: bionet.software
Subject: Complete (small) genome wanted
Summary: Complete (small) genome wanted
Keywords: genome
Message-ID: <1993Apr5.040245.25101@ramsey.cs.laurentian.ca>
Date: 5 Apr 93 04:02:45 GMT
Organization: Dept. of Computer Science, Laurentian University, Sudbury, ON
Lines: 14


Work is proceeding on a small gene analysis program I am working on.
With the package, I would like to include the entire sequenced genome
of some organism (one that has a small genome).  I was thinking
that phage T4 might fit the bill.  Anyway, does anybody know where
I could ftp such a thing (perhaps in GenBank format).  I do not
have any other software running on our mainframe, and I do not have
access to a cd-rom (i.e. I have no way of searching the entire GenBank
library).  If anyone knows where I could ftp some small but completely
sequenced genome (and only that genome), please send me some email.
Thanks.

Shawn Abigail
abigail@ramsey.cs.laurentian.ca

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: r.nakisa@ic.ac.uk ((Ramin Charles Nakisa) ramin)
Newsgroups: bionet.software
Subject: Re: Molbio Software Standard
Message-ID: <1993Apr5.173120.6378@gserv1.dl.ac.uk>
Date: 5 Apr 93 18:31:20 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 37
Original-To: bio-soft@uk.ac.daresbury
X-Popmail-Charset: British

Bradley K. Sherman writes

> It is very common for a single successful run of a program
> to be the last use of that program!  It is often the case that
> a simple graph or picture is the culmination of hundreds of hours
> of moving data from one form to another, filtering out
> noise, and applying a special purpose mathematical transform
> -- often some arcane algorithm thought up by Gauss after one
> too many Schnapps on a chilly night in 1843 and never before
> implemented in any form more concrete than a doctoral dissertation.
>
> By the time the software is cast into a robust form, thoroughly
> vetted and outfitted with its direct manipulation interface
> for Curses, Windows , Windows NT, Mac, OS/2, OpenLook, NeXtStep
> Motif, VMS, ... and then retested for window manager idiosyncrasies
> the problem it solves may be of no interest.

From my experience with molbio software, it is usually the same programs 
that are used repeatedly, such as translation, ORF detection, restriction 
analysis and so on.  If there were a library of standard routines to carry 
out these manipulations with a simple, consistent interface it would be 
much easier to write and use multi-platform software.  Of course there are 
always Sherman's gaussian outliers 8-), programs which are used only once, 
but even these would be easier to develop given a standard library.

Having established a standard, it becomes easier to assemble several 
programs by different authors into a single package as Don Gilbert 
has done for the Mac.  I think such a package would be worthwhile, and 
although it may not please all of the people all of the time, it would 
please most of the people some of the time.
/--------------------------------------------------------------------------\
< Ramin Charles Nakisa, "She walks in beauty Tel:    071 589-5111 x 6729   >
> Biophysics Section,   As the night of      FAX:    071 589-0191          <
< The Blackett Lab,     starry skies and     EMAIL:                        >
> Imperial College,     cloudless climes..."         ramin@ic.ac.uk        <
< London SW7 2BZ.                                    mbrcn@seqnet.dl.ac.uk >
\--------------------------------------------------------------------------/

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!hsdndev!nmr-z!Frodo.MGH.Harvard.EDU!CHERRY
From: cherry@Frodo.MGH.Harvard.EDU
Newsgroups: bionet.software
Subject: Re: ACEDB Workshop in Boston, July 28-31
Message-ID: <1993Apr5.171506.4296@nmr-z.mgh.harvard.edu>
Date: 5 Apr 93 17:15:06 GMT
References: <930405095700.20608caf@Frodo.MGH.Harvard.EDU>
Sender: usenet@nmr-z.mgh.harvard.edu (User for USENET news postings)
Reply-To: cherry@Frodo.MGH.Harvard.EDU
Distribution: bionet
Organization: Dept Molecular Biology, Massachusetts General Hospital
Lines: 6
Nntp-Posting-Host: frodo.mgh.harvard.edu

>>      Otto Rieter, DKFZ, Heidelberg, Germany

My apologies to Otto for mispelling his name. The correct spelling is
Ritter.

Mike

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!FRODO.MGH.HARVARD.EDU!CHERRY
From: CHERRY@FRODO.MGH.HARVARD.EDU (Mike Cherry 726-5955)
Newsgroups: bionet.software
Subject: ACEDB Workshop in Boston, July 28-31
Message-ID: <930405095700.20608caf@Frodo.MGH.Harvard.EDU>
Date: 5 Apr 93 13:57:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 85


          A C E D B   D E V E L O P E R ' S   W O R K S H O P

                           July 29-31, 1993
                    Massachusetts General Hospital
                         Boston, Massachusetts


A  workshop for developers and curators  of the  ACEDB genome database
software will be held  at  Massachusetts General Hospital in  downtown
Boston  July  29-31, 1993.  The goal  of this  meeting is  to  promote
interaction  between  the many  groups that are  currently  developing
genome databases using the ACEDB software.

ACEDB was developed by Richard Durbin and Jean Thierry-Mieg for use by
the C.  elegans  genome  effort.  Currently many groups have found the
ACEDB user  interface and database to be  very useful  in  providing a
wide variety of genome related  information.  A very  partial  list of
the current  projects using  the  ACEDB software includes C.  elegans,
Arabidopsis, human, Drosophila, wheat and pine tree genome efforts.

There is  no  registration fee for this  workshop. However,  space  is
limited to 60  people so please notify us of your  interest.  We  will
also notify  you  of  the  final details.  A block of rooms  has  been
reserved at a hotel across the street from the meeting site.  The rate
is $105 per night for either  single or double occupancy.  If you wish
to reserve a room at this hotel and are in the US call Holiday Inn  at
800-HOLIDAY and give the convention code MOL.  If you are calling from
outside the US you'll need to dial direct to +617-742-7630 and mention
the Department of Molecular Biology meeting.

Details  for the  meals  have  not  been  finalized  but we anticipate
breakfast, lunch and perhaps one dinner will be provided at no charge.

A  number of workstations will  be available  for  live demonstrations
during the formal sessions as well as during discussion periods.

A tentative list of topics that will be included in the agenda are:

ACEDB Database and Interface:
	o Data models and design
	o Query interface
	o Metadata
	o Data verification
	o Images
	o Physical and Genetic Map tools

ACEDB Community:
	o Updates on how various groups are using ACEDB
	o Species specific enhancements
	o Novel Graphic Displays
	o Costumization
	o Discussion of future directions and needs

Additional Topics:
	o data entry/editing
	o analysis tools

New Developments:
	o new Client/Server for ACEDB
	o Otto Rieter's Relational/ACEDB link
	o Interactions of ACEDB with remote sequence databases
	o LBL Enhancements

A partial list of speakers:
	Richard Durbin, MRC-LMB, Cambridge, UK
	Jean Thierry-Mieg, CNRS, Montpellier, France
	Susanne Lewis, LBL, Berkeley, California
	John McCarthy, LBL, Berkeley, California
	Otto Rieter, DKFZ, Heidelberg, Germany
	Sam Cartinhour, MGH, Boston, Massachusetts
	Mike Cherry, MGH, Boston, Massachusetts


Please contact  us  with any questions and please let  me know if  you
plan to  attend.   The meeting room can only hold a limited number  of
people  and  we  are organizing a  small  network  of workstations for
demonstrations.

Mike Cherry and Sam Cartinhour
Department of Molecular Biology
Massachusetts General Hospital
Boston, MA  02114
FAX:   +617-726-6893
Internet: curator@frodo.mgh.harvard.edu

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!uwm.edu!zaphod.mps.ohio-state.edu!howland.reston.ans.net!noc.near.net!uunet!mcsun!dxcern!hprd26a!tonko
From: tonko@hprd26a.cern.ch (Tonko Ljubicic)
Newsgroups: bionet.software
Subject: Re: Free EMBL-database query/search software ?
Message-ID: <tonko.734023501@hprd26a>
Date: 5 Apr 93 15:25:01 GMT
References: <tonko.733842493@hprd26a>
Sender: news@dxcern.cern.ch (USENET News System)
Organization: CERN European Lab for Particle Physics
Lines: 35

In <tonko.733842493@hprd26a> tonko@hprd26a.cern.ch (Tonko Ljubicic) writes:

>Does anybody know of a free (or cheap) EMBL database searching
>software ? In the manner of CD-SEQ from the EMBL CD for instance.
>Preferably for DOS (Windows?) and Unix (X11?).


I'm new to this "bionet software" world so let me please rephrase my
question since the responses I got were too general...

The question is :

Does somebody have any experience/opinions/recommendations about 
the freely available EMBL-database search/query tools ?


------

Is anybody out there using any of them ? Or everybody uses the
mail-server ? Eh ? 

I _KNOW_ about the EMBL ftp server, but from the 1-liners in the help/doc
files I can't find any package that would compile and run on a general Unix
workstation with a general C compiler. Of course, I can try to hack some of
these packages to make them run on my system(s) but is it worth the trouble ?
Is there any generally accepted tool ? 

	-- Tonko


--
ljubicic@dxcern.cern.ch   ljubicic@cernvm.bitnet   tonko@hprd26a.cern.ch
Ante Tonko Ljubicic       Division PPE       
CERN                      (European Laboratory for Particle Physics)
1211 Geneve 23            Switzerland

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: s.fraser@ic.ac.uk
Newsgroups: bionet.software
Subject: Software for analysis of electrophoretic data
Message-ID: <1993Apr5.083350.27298@gserv1.dl.ac.uk>
Date: 5 Apr 93 09:33:57 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 22
Original-To: bio-soft@uk.ac.daresbury (bio-soft newsgroup)
X-Mailer: ELM [version 2.3 PL3]


I have already posed this question to the InfoMac
digest, so apologies to those of you who have seen it
already. However, I had little helpful response last time,
so hope you people in this newsgroup can help me.

I am looking for some software, preferably in the public
domain or shareware, for the analysis of data from electro-
phoresis, to run on a Macintosh computer.
The package BioSys, which runs on DOS, VMS etc. does most
of the required analyses (such as calculations of genetic
distance and heterozygosity, and clustering), but is there
a more friendly Macintosh alternative?

Please respond directly to me, and I will summarize to the
newsgroup.

Simon Fraser
Centre for Population Biology
Imperial College at Silwood Park
UK
s.fraser@ic.ac.uk

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!agate!usenet.ins.cwru.edu!magnus.acs.ohio-state.edu!zaphod.mps.ohio-state.edu!caen!uvaarpa!murdoch!darwin.clas.Virginia.EDU!rbm8p
From: rbm8p@Virginia.EDU (Rick MacDonald)
Newsgroups: bionet.software,bionet.xtallography
Subject: SAXS software sought
Message-ID: <C50oEL.y7@murdoch.acc.Virginia.EDU>
Date: 5 Apr 93 15:30:21 GMT
Sender: usenet@murdoch.acc.Virginia.EDU
Organization: University of Virginia
Lines: 15
Xref: biosci bionet.software:4721 bionet.xtallography:243
Originator: rbm8p@darwin.clas.Virginia.EDU


I seek SAXS software.

Would some kind soul who is familiar with current methods
in small-angle x-ray scattering data analysis point me
toward software that implements "Moore's method" or some
other recipe for computing a radial distribution of
distances from solution scattering data?  What do SAXS
spectroscopists use?

In the absence of software, comments on the implementing the
transform (Intensity ---> spherically averaged density) 
would be much appreciated.

Rick

From owner-software@net.bio.net Sun Apr 04 23:00:00 1993
Path: biosci!WITSVMA.WITS.AC.ZA!047NAIL
From: 047NAIL@WITSVMA.WITS.AC.ZA (Paul Nailand)
Newsgroups: bionet.software
Subject: DOS molecular virology software
Message-ID: <9304051213.AA20024@net.bio.net>
Date: 5 Apr 93 12:13:16 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 21

I apologise for the second posting of this message but I am trying to
help some university colleagues locate appropriate software and have had
to ask them to refine their needs. They follow below, any suggestions etc
etc etc will be most appreciated.

-----
"We have about 40 computers, all 386 and beyond, connected in a Novell
v3.11 network. Our molecular virology projects at the moment are mostly
concerned with the molecular epidemilogy of Polio, Hepatitis B and HIV in
South Africa. We have developed or are developing in house PCR tests for
these as well as many other viruses including HCV. So we are interested
in primer selection, comparison of local sequences with published data,
dendrogram drawing and the like. Restriction enzyme sites within the PCR
fragments we produce and analysis of several subtypes simultaneously is
also of interest." -- Sheila Bouwer, National Institute of Virology
-----

Thankyou
Paul Nailand
University of the Witwatersrand
Email: 047nail@witsvma.wits.ac.za

From owner-software@net.bio.net Mon Apr 05 23:00:00 1993
Path: biosci!daresbury!keele!uknet!pipex!uunet!utcsri!utnut!torn!pulp.cs.laurentian.ca!abigail
From: abigail@ramsey.cs.laurentian.ca (Shawn Abigail)
Newsgroups: bionet.software
Subject: Genetic Codes
Summary: Genetic Codes
Keywords: genetic code
Message-ID: <1993Apr6.151333.5307@ramsey.cs.laurentian.ca>
Date: 6 Apr 93 15:13:33 GMT
Organization: Dept. of Computer Science, Laurentian University, Sudbury, ON
Lines: 13


I downloaded the list of genetic codes (SGC0, SGC1, etc), but I have
one question.  Do all of the codes listed recognize AUG as an
initiation codon?  Some of the codes do not list any initiation
codons (does this mean AUG is accepted?), some list alternate
initiation codons (does this mean that AUG is also acceptable?) and
some list alternates and AUG (this really confuses me, because I
would not expect to see AUG listed if it was implied).  Thanks for
any help you can provide, because there is nobody here at my university
that can help me with this.

Shawn Abigail
abigail@ramsey.cs.laurentian.ca

From owner-software@net.bio.net Mon Apr 05 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!uunet!haven.umd.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: Complete (small) genome wanted
Keywords: genome
Message-ID: <1993Apr5.143855.8829@welchgate.welch.jhu.edu>
Date: 5 Apr 93 14:38:55 GMT
References: <1993Apr5.040245.25101@ramsey.cs.laurentian.ca>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 40

In article <1993Apr5.040245.25101@ramsey.cs.laurentian.ca> abigail@ramsey.cs.laurentian.ca (Shawn Abigail) writes:
>
>Work is proceeding on a small gene analysis program I am working on.
>With the package, I would like to include the entire sequenced genome
>of some organism (one that has a small genome).  I was thinking
>that phage T4 might fit the bill.  Anyway, does anybody know where
>I could ftp such a thing (perhaps in GenBank format).  I do not
>have any other software running on our mainframe, and I do not have
>access to a cd-rom (i.e. I have no way of searching the entire GenBank
>library).  If anyone knows where I could ftp some small but completely
>sequenced genome (and only that genome), please send me some email.
>Thanks.
>
A gopher search of genbank for:

complete and genome

yields *lots* of (too many) candidates for you.  If you want a phage
genome a search for:

complete and genome and phage

yields about 6 complete genomes for you, ranging in size from 
3.5 kb (Bacteriophage MS2) to 46.6 kb (Bacteriophage lambda).  

A search for 

complete and genome and bacteriophage 

will yield a few more genomes in the same size range.

If you don't know what gopher is don't worry it's free and on the net,
write me a note if you need information on how to get started with
gopher.

Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Mon Apr 05 23:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!comp.bioz.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: bionet.software
Subject: Re: Free EMBL-database query/search software ?
Message-ID: <1993Apr6.060708.4535@comp.bioz.unibas.ch>
Date: 6 Apr 93 06:07:08 GMT
References: <tonko.733842493@hprd26a> <tonko.734023501@hprd26a>
Sender: usenet@comp.bioz.unibas.ch (NEWS transaction account)
Reply-To: doelz@urz.unibas.ch
Organization: EMBnet Switzerland [BASEL]
Lines: 38
Nntp-Posting-Host: biox.embnet.unibas.ch

In article <tonko.734023501@hprd26a>, tonko@hprd26a.cern.ch (Tonko Ljubicic) writes:
|> 
|> Does somebody have any experience/opinions/recommendations about 
|> the freely available EMBL-database search/query tools ?
|> 

As I responded to you privately already, there is a lot of software 
out there which you can use. Amos Bairoch has assembled a very useful 
list of Molecular Biology Archives and Mailservers which is available 
on many FTP sites (at ours, it is in /info). With respect to query systems, 
the Sequence Retrieval Software (SRS), copyrighted by Thure Etzold, is 
just going into Beta testing. ATLAS from the PIR International as distributed
on their CD should also run on UNIX.
 
|> Is anybody out there using any of them ? Or everybody uses the
|> mail-server ? Eh ? 

I already offered to you the services of the Swiss National EMBnet node. 
Nodes of the European Molecular Biology Network (EMBnet) are prepared 
to answer questions of this kind specifically and detailed. 

|> these packages to make them run on my system(s) but is it worth 
|> the trouble ?

Maybe you enlighten the audience what your UNIX is like. Unfortunately,
UNIX comes in so many flavours that you might fight very hard in 
hacking your code if you got a rare brand. 


-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |
|   Klingelbergstrasse 70          | FAX     x41 61 261- 6760 or 267- 2078     
|     CH 4056 Basel                | TEL     x41 61 267- 2076 or 2247    |   
+------------- bioftp.unibas.ch is the SWISS EMBnet node ----------------+
               -----------------------------------------

From owner-software@net.bio.net Mon Apr 05 23:00:00 1993
Path: biosci!news.miami.edu!usenet.ufl.edu!usenet.cis.ufl.edu!caen!zaphod.mps.ohio-state.edu!usc!usc!not-for-mail
From: mhess@neuroblast.hsc.usc.edu (Mark A. Hess)
Newsgroups: bionet.software
Subject: Predicting RNA hairpins
Summary: Finding single most stable RNA hairpin
Keywords: RNA/secondary structure
Message-ID: <1pqnskINN763@neuroblast.hsc.usc.edu>
Date: 6 Apr 93 01:54:28 GMT
Sender: nntp@neuroblast.hsc.usc.edu
Organization: University of Southern California, Los Angeles, CA
Lines: 9
NNTP-Posting-Host: neuroblast.hsc.usc.edu

I'm looking for software that will find the single most stable stem-loop in an RNA sequence. I have tried the (M)FOLD programs of Dr. M. Zuker, but they don't
really do this. The structures consist of many weak hairpins, the sum of which
yields a modest negative free energy for my sequences. I've also tried a
program called stem-loop and fed the individual hairpins to FOLD. This proved 
too time consuming (hundreds of stem-loops are found) and the structures are
weak. I'd prefer to systematically search for all single hairpins in the range of say, -15 to -20 kcal/mol free energy-about 30% less stable than the aggregate structures.

Thanks in advance for any help.                                                                                                                                                                                                              Mark A. Hess
mhess@hsc.usc.edu

From owner-software@net.bio.net Mon Apr 05 23:00:00 1993
Path: biosci!TOURS.INRA.FR!jdacheux
From: jdacheux@TOURS.INRA.FR (Jean-Louis.Dacheux)
Newsgroups: bionet.software
Subject: registration
Message-ID: <9304061608.AA07199@tours.tours.inra.fr>
Date: 6 Apr 93 16:08:54 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 7

I am interesting to receive regularly informations about the
News Bio-soft. What is the procedure to follow to do that?
Jean-Louis Dacheux.
Lab Physiology of Reproduction
INRA 37380 Monnaie 
France.
Thanks you

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!haven.umd.edu!darwin.sura.net!paladin.american.edu!howland.reston.ans.net!zaphod.mps.ohio-state.edu!sdd.hp.com!decwrl!decwrl!csus.edu!news.ucdavis.edu!hamlet.ucdavis.edu!ez005587
From: ez005587@hamlet.ucdavis.edu (David J. Meyer)
Newsgroups: bionet.software
Subject: Data acquisition and analysis
Message-ID: <C54LAq.FD7@ucdavis.edu>
Date: 7 Apr 93 18:13:35 GMT
Sender: usenet@ucdavis.edu
Organization: University of California, Davis
Lines: 18
X-Newsreader: Tin 1.1 PL3

Hello, netters!

	I am looking for some help with analysis of chromatographic profiles.

1) I have a number of chart recordings which I would like to import into
some type of program which will allow me to integrate user-defined peaks.
I am aware of some programs able to do this, but would like to hear from
users about the capabilities of different packages. I would prefer
packages for the Mac.

2) I would like to connect an old 286 to our FPLC to avoid such problems
in the future. Some of the commercial packages designed *specifically* to
do this seem a bit pricey. What's the best way to do this for less money?

	Thanks in advance!

David J. Meyer
djmeyer@ucdavis.edu

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!uunet!wupost!bcserv!eric
From: eric@bcserv.wustl.edu (Hugo (Eric))
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Bionet faq in Win3.1 help format, suggestions solicited
Keywords: FAQ, helpfiles, hypertext
Message-ID: <eric.734188857@bcserv>
Date: 7 Apr 93 13:20:57 GMT
Organization: Washington University in Saint Louis, MO USA
Lines: 13
Xref: biosci bionet.molbio.methds-reagnts:4992 bionet.software:4729
NNTP-Posting-Host: bcserv.wustl.edu

Dear Bionetters,
     I am in the process of compiling various articles from USENET
bionet newsgroups into a Windows 3.1 help file.  Before I get too
involved I'm soliciting opinions from the Net as to what would
be most valuable to include.  If you have any suggestions please
email me.  When I get a preliminary help file done I'll make it
freely available to whoever would like it.
                    Thanks for any feedback,      Eric ;-)
-- 
  Eric R. Hugo, Postdoctoral Research Associate |eric@bcserv.wustl.edu
  Dept. of Biochemistry and Molecular Biophysics|                
  Washington University School of Medicine      |               
  Box 8231, St. Louis, MO 63110_________________| (314) 362-3342

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!uunet!zaphod.mps.ohio-state.edu!moe.ksu.ksu.edu!kuhub.cc.ukans.edu!husc-news.harvard.edu!husc.harvard.edu!robison1
From: robison1@husc10.harvard.edu (Keith Robison)
Newsgroups: bionet.software
Subject: Re: Genetic Codes
Keywords: genetic code
Message-ID: <robison1.734187445@husc.harvard.edu>
Date: 7 Apr 93 12:57:25 GMT
References: <1993Apr6.151333.5307@ramsey.cs.laurentian.ca>
Lines: 42
Nntp-Posting-Host: husc10.harvard.edu

abigail@ramsey.cs.laurentian.ca (Shawn Abigail) writes:


>I downloaded the list of genetic codes (SGC0, SGC1, etc), but I have
>one question.  Do all of the codes listed recognize AUG as an
>initiation codon?  Some of the codes do not list any initiation
>codons (does this mean AUG is accepted?), some list alternate
>initiation codons (does this mean that AUG is also acceptable?) and
>some list alternates and AUG (this really confuses me, because I
>would not expect to see AUG listed if it was implied).  Thanks for
>any help you can provide, because there is nobody here at my university
>that can help me with this.

>Shawn Abigail
>abigail@ramsey.cs.laurentian.ca

I don't have a reference for this (and I need one too!) but the
general rules are:

	1) Eukaryote nuclei use only AUG, translated as Met.
	2) Bacteria use AUG mostly, but GUG, CUG, and UUG sometimes.
	   It is always translated to fMet.
	3) Some mitochondria use a whole host of initiators, but
	   still translate them to Met.
	4) Chloroplast genes use AUG translated as Met, but in
	   some cases the AUG is created through RNA editing.


Any corrections/additions/expansions will be appreciated -- I'm doing
this all from (error-prone) memory.

It's sort of a wierd place to look, and they have some subtle errors,
but one place that has these listed is the documentation for NCBI's
ASN.1 Tool Library, available via FTP from ncbi.nlm.nih.gov.


Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison@biosun.harvard.edu 

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!ITSA.UCSF.EDU!jharper
From: jharper@ITSA.UCSF.EDU (M. Jane Harper)
Newsgroups: bionet.software
Subject: statistics packages for Windows
Message-ID: <9304070321.AA15646@itsa.ucsf.EDU>
Date: 7 Apr 93 03:21:46 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 11

I'd be curious to see what the bioscientists on the Net have found useful in
the way of statistics packages, especially those which run under Windows.
Our campus statisticians are good at formulas but not really computer mavens,
and make funny faces when I say "But I'm running Windows ..."  :-)

Any input would be valued.

Jane Harper
Doctoral Student, Neuroscience/Nursing
University of California at San Francisco
jharper@itsa.ucsf.edu

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!pipex!uunet!noc.near.net!howland.reston.ans.net!zaphod.mps.ohio-state.edu!saimiri.primate.wisc.edu!usenet.coe.montana.edu!news.u.washington.edu!news.u.washington.edu!news
From: mparker@fred.fhcrc.org (Michael Parker)
Newsgroups: bionet.software
Subject: Searching protein database by size
Message-ID: <1pv0umINNqn4@shelley.u.washington.edu>
Date: 7 Apr 93 16:53:42 GMT
Organization: FHCRC
Lines: 3
NNTP-Posting-Host: 140.107.32.73
X-UserAgent: Nuntius v1.1.1d13
X-XXDate: Wed, 7 Apr 93 08:55:40 GMT

I want to find all yeast sequences in the protein database and translated
nucleic acid database over 150 Kd to 200Kd.  Anyone know of a way to do
this?

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: mbg@mrc-lmb.cam.ac.uk (Gerstein "M.")
Newsgroups: bionet.software
Subject: Does a Program for Characterizing Grooves on Protein Surfaces Exist?
Message-ID: <1993Apr7.131920.5938@gserv1.dl.ac.uk>
Date: 7 Apr 93 18:21:52 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 8
Original-To: bio-software@uk.ac.daresbury

Does a program for characterizing grooves on protein surfaces exist?
That is, does anyone know of program which takes a list of atomic
coordinates and gives as output an indication of whether an atom
exposed on the surface is deep in a groove or sticking out into
solution?  A simple surface area calculation (i.e. Lee & Richards) is
not sufficient.

mark gerstein	(mbg@mrc-lmb.cam.ac.uk)

From owner-software@net.bio.net Tue Apr 06 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!natinst.com!news.dell.com!swrinde!sdd.hp.com!zaphod.mps.ohio-state.edu!moe.ksu.ksu.edu!usenet-feed.umr.edu!cnews
From: snayar@next3.cs.umr.edu (Sanjay Nayar)
Newsgroups: bionet.software
Subject: Paper by Kececioglu and Myers
Keywords: fragmen assembly
Message-ID: <1993Apr7.184738.29190@umr.edu>
Date: 7 Apr 93 18:47:38 GMT
Sender: cnews@umr.edu (UMR Usenet News Post)
Reply-To: snayar@cs.umr.edu
Organization: University of Missouri-Rolla, Missouri's Technological University
Lines: 13
Nntp-Posting-Host: next9.cs.umr.edu


	I am looking for the follwing paper, or a complete reference to it.
If someone could email me either, it would be appreciated very much.

	Kececioglu, J. and Myers E.W. (1989).  "A robust and automatic
	fragment assembly system."

Thanks in advance,

--
Sanjay Nayar                |  As often as a study is cultivated by narrow 
University of Missouri-Rolla|  minds, they will draw from it narrow 
snayar@cs.umr.edu           |  conclusions.

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!TIFRVAX.BITNET!SMITRA
From: SMITRA@TIFRVAX.BITNET
Newsgroups: bionet.software
Subject: SUB CANCELLATION
Message-ID: <01GWS1KZIQCW0006TT@tifrvax.tifr.res.in>
Date: 8 Apr 93 13:13:25 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 4

F7 ID LIKE MY SUBSCRIPTION TO THE BIOSOFT NEWSGROUP
CANCELLED.
THANKS,
ROMIT

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!ICGEB.TRIESTE.IT!pongor
From: pongor@ICGEB.TRIESTE.IT (Sandor Pongor)
Newsgroups: bionet.software
Subject: ICGEB/EMBnet Course: Computers in Molecular Biology
Message-ID: <9304081256.AA05187@icgeb.trieste.it>
Date: 8 Apr 93 12:57:54 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 118


                             Practical Course 
                "Computer Methods in Molecular Biology"

   International Centre for Genetic Engineering and Biotechnology
                     14-23 July 1993, Trieste-Italy

                Co-sponsored by ICGEB and EMBnet/BRIDGE

Organizer:	Sandor Pongor, ICGEB Trieste, Italy

Faculty:	Amos Bairoch, University of Geneva, Geneva, Switzerland
		Dennis Benson, NCBI-NIH, Bethesda, USA
		Martin Bishop, Medical Research Council, HGMP, Cambridge, UK
		Miklos Cserzo, Institute of Enzymology, Budapest, Hungary
		Reinhard Doelz, Biozentrum, Basel, Switzerland
		David Judge, University of Cambridge, Cambridge, UK
		Jack Leunissen, University of Nijmegen, The Netherlands
                Peter Rice, EMBL, Heidelberg, Germany
		Cecilia Saccone, University of Bari, Bari, Italy
 		Gyorgy Simon, ICGEB Trieste, Italy
 
Topics:		Introduction to Computer Operating Systems
		Computer Communications, Networking, File Transfer, 
		Electronic Mail, Bulletin Boards
		Molecular Biology Databases
		Sequence Homology Searches, Alignments 
		Multiple Alignment, PCR Primer Design
		Sequence Patterns, Distant Protein Homologies
		Molecular Evolution: Quantitative and Qualitative Aspects
		Genome Projects 

Registration is limited to 30 participants.

Prerequisites: Participants must have a basic knowledge of biochemistry 
and molecular biology, a basic familiarity with computer uses and a need 
for DNA or protein sequence analysis for their ongoing research.

In order to apply, submit the below participation form via e-mail, FAX 
or normal mail to

	Ms. Diana Viti, ICGEB, Padriciano 99, 34012 Trieste, ITALY. 
	Telephone: +39-40-3757333, Fax: +39-40-226555, 
	Telex: 460396 ICGEBT I, Email: viti@icgeb.trieste.it

Closing date for applications 31 May 1993.

ICGEB will provide accommodation and local hospitality to participants from 
ICGEB Member Countries. Travel to and from Trieste will normally be borne by
the participants. There is no registration fee.

ICGEB MEMBER COUNTRIES:
Afghanistan, Algeria, Argentina, Bhutan, Bolivia, Brazil, Bulgaria, Chile, 
China, Colombia, Congo, Costa Rica, Croatia, Cuba, Ecuador, Egypt, Greece, 
Hungary, India, Indonesia, Iran, Iraq, Italy, Kuwait, Mauritania, Mauritius, 
Mexico, Morocco, Nigeria, Pakistan, Panama, Peru, Poland, Russia, Senegal, 
Sri Lanka, Sudan, Syria, Thailand, Trinidad & Tobago, Tunisia, Turkey, 
Venezuela, Viet Nam, Yugoslavia, Zaire

                      --- Cut here ---

___________________________________________________________________________
      INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY

                      MEETINGS * COURSES * WORKSHOPS
                            PARTICIPATION FORM
                         (viti@icgeb.trieste.it)
___________________________________________________________________________
MEETING/COURSE/WORKSHOP.TITLE

           COMPUTER METHODS IN MOLECULAR BIOLOGY, 14-23 JULY, 1993
___________________________________________________________________________
DATES............|
LOCATION.........|
___________________________________________________________________________
SURNAME..........|
FIRSTNAME........|
SEX..............|
DATE.OF.BIRTH....|
AGE..............|
COUNTRY.OF.BIRTH.|
NATIONALITY......|
___________________________________________________________________________
FULL.BUSINESS.ADDRESS

___________________________________________________________________________
TELEPHONE.NUMBER.|
FAX.NUMBER.......|
TELEX.NUMBER.....|
E-MAIL.ADDRESS...|
___________________________________________________________________________
HOW.WILL.YOUR.RESEARCH.BENEFIT.BY.YOUR.PARTICIPATION.IN.THE.MEETING/COURSE/
WORKSHOP.(NO.MORE.THAN.5.LINES.OF.TEXT)

___________________________________________________________________________
RESEARCH.AREA.OF.INTEREST
___________________________________________________________________________
PRESENT.POSITION
___________________________________________________________________________
ACADEMIC.QUALIFICATIONS.(DEGREE/YEAR/INSTITUTE)

___________________________________________________________________________
INSTITUTES.OF.WORK.SINCE.FORMAL.EDUCATION

___________________________________________________________________________
FELLOWSHIPS.HELD

___________________________________________________________________________
PREVIOUSLY.ATTENDED.ICGEB.MEETINGS/COURSES/WORKSHOPS

___________________________________________________________________________
SHORT.LIST.OF.RELEVANT.PUBLICATIONS

___________________________________________________________________________





From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!gatech!emory!emoryu1!emoryu1.cc.emory.edu
From: bcresas@emoryu1.cc.emory.edu (Scott Sammons)
Newsgroups: bionet.software,bit.listserv.info-gcg
Subject: Looking for menu shells for UNIX GCG?
Keywords: GCG
Message-ID: <2586@emoryu1.cc.emory.edu>
Date: 8 Apr 93 16:16:02 GMT
Sender: news@emory.edu
Reply-To: bcresas@emoryu1.cc.emory.edu
Followup-To: bionet.software
Organization: Emory University, Atlanta GA, Biomolecular Computing Resource
Lines: 11
Xref: biosci bionet.software:4743
Nntp-Posting-Host: emoryu1.cc.emory.edu

Has anyone written any menu shells for the GCG UNIX version?
I know there are several for VMS, but I haven't found any for UNIX.

Scott A. Sammons

==============================================================================
| Scott A. Sammons                                           (404) 727-2780  |
| Emory University                                      FAX: (404) 727-3659  |
| Biomolecular Computing Resource                                            |
| 3025 Rollins Research Center                                               |
| Atlanta, GA 30322                 Internet:  bcresas@emoryu1.cc.emory.edu  |                                                                                              ==============================================================================

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!spool.mu.edu!agate!garnet.berkeley.edu!southbay
From: southbay@garnet.berkeley.edu
Newsgroups: bionet.software,biz.comp.software
Subject: Short Courses on Software Testing & Metrics
Message-ID: <1q1npk$i93@agate.berkeley.edu>
Date: 8 Apr 93 17:35:48 GMT
Organization: University of California, Berkeley
Lines: 37
Xref: biosci bionet.software:4742
NNTP-Posting-Host: garnet.berkeley.edu

U.C. Berkeley
Continuing Education in Engineering
Announces 2 Short Courses in 
Software Testing and Metrics


Software Testing (April 19-21, 1993)

This intensive three-day course covers both the current industrial practices and
advanced technologies available to successfully implement and sustain an
improved software testing program.  The advanced software testing technologies
discussed are intended to encourage the planning of future enhancements to
software test programs.

Lecturers: Warren Harrison, Ph.D., Paul W. Oman, Ph.D., Mark Wiley

Software Metrics (April 22-23, 1993)

Measurement is an essential part of improving the software development process.
Measurement facilitates the objective characterization and baselining of an
organizations current software assets, as well as providing a method to
characterize its evolution and improvement.  This course covers both the
theoretical foundations of measurement and software metrics, as well as their
application to improve and characterize the software development process.

Lecturers: Gene Miluk, M.S., Warren Harrison, Ph.D.


For more information (complete course descriptions, outlines, instructor bios,
etc.) contact:

Harvey Stern
U.C. Berkeley Extension/Southbay
800 El Camino Real Ste. 150
Menlo Park, CA 94025
Tel: (415) 323-8141
Fax: (415) 323-1438

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!natinst.com!news.dell.com!swrinde!zaphod.mps.ohio-state.edu!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: Looking for the program Gene Jockey.  Thanks!
Keywords: gene, jockey, mac
Message-ID: <1993Apr8.171416.1032@welchgate.welch.jhu.edu>
Date: 8 Apr 93 17:14:16 GMT
References: <47549@sdcc12.ucsd.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 107

In article <47549@sdcc12.ucsd.edu> ericg@jeeves.ucsd.edu (Eric Geerdes) writes:
>Greetings from San Diego,
>
>We're trying to find info on the program Gene Jockey.
>
>Don't know if it is public domain or not--but we do know it's
>for the Mac.
>
>Thanks for any help you might come up with.
>
>-Eric
>UCSD Biology Computer Services
>ericg@ucsd.edu
>


Gene Jockey is commercial - I'm including a little information below.
You can find a demo version of this program by gopher or anonymous ftp
from several sites - one of them being ftp.bio.indiana.edu in the molbio/mac
directory.

Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu


--------------------

 GeneJockey A program for editing, manipulating and analysing nucleic acid and protein sequences

DEMO VERSION.
	Please note that the demo version will not save or print sequences (it can,
however print this 'Read Me' window).  The global clipboard is disabled, so data
cannot be transferred into or out of the program.  The demo version can open
only GeneJockey files and Genbank files (NOT text files, DNA inspector files or
IBI Pustell files).  The communications routines are also disabled. None of
these restrictions apply to the full version.

Introduction

	GeneJockey is a program for the Apple Macintosh which makes full use of the
machine's WIMP interface.  Nucleic acid and protein sequences can be entered
from the keyboard or imported as files in other formats (Currently the program
can read or write nucleic acid files in the format of Textco's DNA Inspector and
IBI's Pustell programs.  Text files corresponding to other formats can be read,
and Genbank files in Macintosh format can be opened ).  The program displays
both sequence data and annotations in the same window, and permits multiple
windows to be open (up to 30) so that sequences can be assembled from several
sources by standard Macintosh editing techniques. Sequences entered by hand may
be verified by re-typing or by having the machine read the sequence back, using
sampled sounds rather than speech synthesis for clarity.
	Standard procedures for manipulating sequences are provided : both types of
sequence may be reversed, and nucleic acid sequences may be complemented,
inverted or translated to protein.  In each case a new window is opened to
contain the modified sequence, the original remaining unchanged.

   Basic database searching facilities are provided, and you may search your own
GeneJockey files or Genbank files or both at once.  You may search the comments
section of the files with keywords entered at the keyboard, or search the
sequence sections using the sequence currently displayed in the front window. In
either case, the program makes a crude estimate of the time required to complete
the search before starting.  Standard search facilities are provided for
searching a single sequence with a short sub-sequence, and the availability of
wild card characters allows consensus sequences to be searched for.

Sequence analysis commands include :

Align:(Simple - display the sequences in the two top windows aligned so that the
longest possible single match is obtained, or Exhaustive - stretch the sequences
where necessary to display as much homology as possible between them).  In
either case the displayed sequences remain fully editable, enabling sequence
fragments read from sequencing gels to be adjusted to obtain the best contig in
the simplest possible manner.

Matrix : Dot-plot matrix between two sequences.


Reading Frames - Display all open reading frames longer than a threshold length,
optionally starting only at a start codon and reading both strands of the
nucleic acid.  Selected areas of open reading frame can then be translated to
protein.

Hydropathicity Plot : The hydropathicity profile of protein sequences may be
displayed using either Kyte and Doolittle or Hopp and Woods methods.

Sequence Information : Displays base counts, molecular weights etc for both a
selected section of sequence and for the entire sequence.

Restriction Analysis : The program contains recognition sequences for about 400
restriction enzymes (You can change these and add more if necessary).   DNA
sequences may be analysed using a preselected list of restriction enzymes drawn
from these, and the results displayed in text form either as individual digests,
as a multiple digest, or as a graphic map. The program can automatically  select
those enzymes which can cut (or not cut) within a selected section of the
sequence.

Requirements

	The program requires a minimum of a Macintosh Plus.  In order to make use of
the Genbank sequence database a hard disk is required, and since this database
currently occupies about 30 Mbyte a large disk is necessary if you want to have
the whole of Genbank available.  If the program is to be used for extensive
database searching a faster machine is recommended to reduce waiting time.

------

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!wupost!howland.reston.ans.net!agate!dog.ee.lbl.gov!network.ucsd.edu!sdcc12!jeeves!ericg
From: ericg@jeeves.ucsd.edu (Eric Geerdes)
Newsgroups: bionet.software
Subject: Looking for the program Gene Jockey.  Thanks!
Keywords: gene, jockey, mac
Message-ID: <47549@sdcc12.ucsd.edu>
Date: 8 Apr 93 16:12:00 GMT
Sender: news@sdcc12.ucsd.edu
Lines: 12
Nntp-Posting-Host: jeeves.ucsd.edu

Greetings from San Diego,

We're trying to find info on the program Gene Jockey.

Don't know if it is public domain or not--but we do know it's
for the Mac.

Thanks for any help you might come up with.

-Eric
UCSD Biology Computer Services
ericg@ucsd.edu

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!wupost!darwin.sura.net!welchgate.welch.jhu.edu!danj
From: danj@welchgate.welch.jhu.edu (Dan Jacobson)
Newsgroups: bionet.software
Subject: Re: Paper by Kececioglu and Myers
Message-ID: <1993Apr8.150213.14816@welchgate.welch.jhu.edu>
Date: 8 Apr 93 15:02:13 GMT
References: <1993Apr7.184738.29190@umr.edu> <ksuiter-080493093658@hurston.zoo.duke.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Lines: 69

In article <ksuiter-080493093658@hurston.zoo.duke.edu> ksuiter@acpub.duke.edu (Karl A. Suiter) writes:
>In article <1993Apr7.184738.29190@umr.edu>, snayar@next3.cs.umr.edu (Sanjay
>Nayar) wrote:
>> 
>> 
>> 	I am looking for the follwing paper, or a complete reference to it.
>> If someone could email me either, it would be appreciated very much.
>> 
>> 	Kececioglu, J. and Myers E.W. (1989).  "A robust and automatic
>> 	fragment assembly system."
>> 
>> Thanks in advance,
>
>Sanjay,
>
>  I searched our library reference database here at Duke (it goes back to
>1988) and it found no references for Kececioglu and Meyers together,
>although there were a number of papers published by each author separately
>on the subject of fragment alignment.
>
>You can track down these references in your library yourself instead of
>relying on the net to do your work for you :-)

My guess is that Sanjay tried and couldn't find it and *then* asked
for help that was beyond his local resources.  The request was quite
specific - it wasn't one of those - "please send me all references on cancer"
requests.  I too have come to the conclusion that the paper doesn't exist
as I couldn't find it in a host of bibliographic databases :-(.  It may
have been a poster at a meeting or some such item that might be mentioned
or even referenced but not appear in the general literature - it's hard
to tell without knowing more about where he found the partial citation.

At any rate he can call Myers and ask him because a little gopher
searching tells me:

A clip from Myers Grant abstract:

-----
-PROJECT NUMBER......5 R01 LM04960-05

PRINCIPAL INVESTIGATOR

MYERS, EUGENE W JR
UNIVERSITY OF ARIZONA
GOULD-SIMPSON BLDG
TUCSON, AZ  85721
PERFORMING ORGANIZATION: UNIVERSITY OF ARIZONA
TITLE   Efficient software for the analysis of biosequences

-----

And his phone number

PHONE: (602) 621-6612

And email:

meyers@cs.arizona.edu

or 

gene@cheltenham.cs.arizona.edu


Best of luck,

Dan Jacobson

danj@welchgate.welch.jhu.edu

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!zaphod.mps.ohio-state.edu!usc!elroy.jpl.nasa.gov!news.claremont.edu!cgsvax.claremont.edu!goldsmig
From: goldsmig@cgsvax.claremont.edu
Newsgroups: bionet.software
Subject: Microscopy HW and SW Request
Message-ID: <1993Apr8.072711.1@cgsvax.claremont.edu>
Date: 8 Apr 93 15:27:11 GMT
Sender: news@news.claremont.edu (The News System)
Organization: The Claremont Graduate School
Lines: 11

I am seeking information on sources of hardware and software required to
capture images taken from microscope slides in any type of DOS compatible
digital format.  I would also appreciate sources of used microscopes
(although I realize that this is probably not the best news group for
such a posting).  I need to keep the costs as low as possible because
this is in support of a personal avocation (the study of local native flora
and fauna) and because my resources are quite limited.

Thank you in advance for any help you might provide.

George Goldsmith

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!wupost!howland.reston.ans.net!gatech!concert!duke!news.duke.edu!hurston.zoo.duke.edu!user
From: ksuiter@acpub.duke.edu (Karl A. Suiter)
Newsgroups: bionet.software
Subject: Re: Paper by Kececioglu and Myers
Message-ID: <ksuiter-080493093658@hurston.zoo.duke.edu>
Date: 8 Apr 93 13:37:44 GMT
References: <1993Apr7.184738.29190@umr.edu>
Sender: news@news.duke.edu
Followup-To: bionet.software
Organization: Duke University
Lines: 32
Nntp-Posting-Host: hurston.zoo.duke.edu

In article <1993Apr7.184738.29190@umr.edu>, snayar@next3.cs.umr.edu (Sanjay
Nayar) wrote:
> 
> 
> 	I am looking for the follwing paper, or a complete reference to it.
> If someone could email me either, it would be appreciated very much.
> 
> 	Kececioglu, J. and Myers E.W. (1989).  "A robust and automatic
> 	fragment assembly system."
> 
> Thanks in advance,

Sanjay,

  I searched our library reference database here at Duke (it goes back to
1988) and it found no references for Kececioglu and Meyers together,
although there were a number of papers published by each author separately
on the subject of fragment alignment.

  You can track down these references in your library yourself instead of
relying on the net to do your work for you :-)


                                                                   Karl
---

=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=
| Karl A. Suiter, Duke University, Zoology Dept., Durham, NC   27706    |
|=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=|
| Voice: (919) 684-2251      |   INTERNET:  ksuiter@acpub.duke.edu      |
| FAX:   (919) 684-6168      |   COMPUSERV: 72701,3543@compserv.com     |
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!usc!howland.reston.ans.net!newsserver.jvnc.net!yale.edu!news.yale.edu!YaleVM.YCC.Yale.Edu!MCKMICP
From: MCKMICP@YaleVM.YCC.Yale.Edu (Michael McKenna)
Newsgroups: bionet.software
Subject: Superfamily Phylogenetics
Message-ID: <16BA9133D2.MCKMICP@YaleVM.YCC.Yale.Edu>
Date: 8 Apr 93 01:53:21 GMT
Sender: news@news.yale.edu (USENET News System)
Organization: Yale University
Lines: 20
Nntp-Posting-Host: yalevm.ycc.yale.edu

I would like to generate a phylogenetic tree of the lipocalin#
superfamily. These sequences are very distantly related, if at#
all, but share a number of common general characteristics, including#
a signal peptide, several pairs of cysteine residues, and a #
molecular weight between 15 and 20 kD. They also share a common #
function; the transport and delivery of hydrophobic molecules#
through an aqueous environment. Several of these molecules have #
had their structures solved, and there is a compelling uniformity#
to their structure, even though the identity is very low at the#
primary level, often on the order of 20%.#
#
I have discovered a number of potential lipocalins in the antennae of#
Drosophila melanogaster which belong to the family of odorant-binding#
proteins. My question is- Is it possible to generate a phylogeny from#
sequence data when only dubious connections can be made with various #
allignment algorithms. Most of the programs I have seen can do a #
resonable job with clearly related molecules. I suspect it can't#
be done reasonably in this particular case. Any suggestions?#
#
Thanks,             Mike McKenna         MCKMICP@YALEVM.YCC.Yale.edu

From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!CSHL.ORG!peters
From: peters@CSHL.ORG (Bobbie Peters - CSHL Computer Center)
Newsgroups: bionet.software
Subject: Auto ftp of databanks
Message-ID: <9304082002.AA18810@phage.cshl.org>
Date: 8 Apr 93 20:02:13 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 23

Hello,
We are trying to set up a system to download the weekly/daily updates
of the various databanks (GB, EMBL, PIR, SP) so we can translate them
into IntelliGenetics on the SUN. IG's TOIGSF program shouldn't have any 
problem doing the translations, but getting the databanks is another
thing.
	Does anyone have a UNIX program already written to go get the 
databanks at a specific time at night  - maybe with something that will 
check to be sure it is the right update to the release I have loaded?
	I am sure I am not the only one to try to do this & I just don't 
want to reinvent the wheel.

Thanks !!
Bobbie Peters
User Liaison

 v v v v v v v v v v v v v v v v v v v v v v v v v v v v v v v v v v
  Cold Spring Harbor Laboratory		 Voice:	(516) 367-8390
  Box 100         			   Fax: (516) 367-9576
  1 Bungtown Road		      Internet: <peters@cshl.org>
  Cold Spring Harbor, NY  11724-2213, USA	  (or theiss@...)
 ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ 


From owner-software@net.bio.net Wed Apr 07 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: GORTI@SBBIOVM.EARN (Guillermo Orti)
Newsgroups: bionet.software
Subject: subscribe
Message-ID: <1993Apr8.185626.27979@gserv1.dl.ac.uk>
Date: 8 Apr 93 18:43:34 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 1
Original-To: bio-software@UK.AC.DARESBURY

please subscribe Guillermo Orti to the list (GORTI@SBBIOVM)

From owner-software@net.bio.net Thu Apr 08 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!swrinde!zaphod.mps.ohio-state.edu!howland.reston.ans.net!agate!netsys!pagesat!news.cerf.net!network.ucsd.edu!sdcc12!jeeves!ericg
From: ericg@jeeves.ucsd.edu (Eric Geerdes)
Newsgroups: bionet.software
Subject: Re: Looking for the program Gene Jockey.  Thanks!
Summary: Here's a sample of responses...  Thanks again folks!
Keywords: gene, jockey, mac
Message-ID: <47604@sdcc12.ucsd.edu>
Date: 9 Apr 93 15:55:44 GMT
References: <47549@sdcc12.ucsd.edu>
Sender: news@sdcc12.ucsd.edu
Lines: 73
Nntp-Posting-Host: jeeves.ucsd.edu

*******************************************************************

Here is a sample of the responses to my post.  What a Group!...

*******************************************************************

At  1:15 PM 4/8/93 -0400, Doug.Eernisse@um.cc.umich.edu wrote:
 >Eric,
 > It is commercial but I believe there is a partly functional
 >demo version around. Have you checked ftp.bio.indiana.edu in
                                        ^^^^^^^^^^^^^^^^^^^
 >the /molbio/mac directory? It is fast and has some interesting
 >capabilities as I recollect.
 > 
 >Doug Eernisse

**********************************
THE DEMO IS THERE JUST AS HE SAID.
**********************************

At  3:23 PM 4/9/93 +0200, Kirk Schnorr wrote:
 >I have used GeneJockey and have found it to be one of the best integrated
 >DNA analysis program I have worked with.  It is available from an English
 >software firm called Biosoft, 22 Hills Road Cambridge, CB2 1JP
 >I am surprized no one has mentioned the package until now.  One reason may
 >be that you have to pay for it.  If I recall it is about 500 German marks.
 > They will send a demo version if asked.  The demo version is the best way
 >to assess the program.
 >
 >Kirk SCHNORR
 >...

At 10:17 AM 4/9/93 -0400, genecodes@aol.com wrote:
 >Hi Eric,
 >...
 >If you are looking for Mac software, you should take a look at Sequencher
 >from Gene Codes.  I know there are some people at UCSD who are doing
 >a reasonable ammount of DNA sequencing. ... There was a short review of
 >Sequencher in the December issue of MacWorld (p. 274).  
 >
 >Send me your surface mail address and I'll see that someone sends you a
 >demo kit.  Sequencher is not as broad an application as Gene Jockey or 
 >the GCG package on the Vax, but it covers sequencing technology in depth,
 >is extremely well designed and easy to use, and is technically way ahead 
 >of the other commercial packages on the market.
 >...
 >Howard Cash
[ contact genecodes@aol.com for more info ]

At  1:31 PM 4/9/93 +0948, Rod Bonfiglioli wrote:
 > >...
 >  the prograsm is mareketed by a firm in cambridge, UK.  the firm will send 
you
 >a crippled demo that is absolutely useless and wont really show you anything the
 >program will do,.  i got a copy of this crippled demo disk, and got very little
 >idea what the program would do, so i didnt bother buying it.  best of luck
 >though.  if no-one else on the net sends you the adress of the firm (i cant
 >think of it off the top top top of my head...) get back to me and i will find
 >the address for you.
 >
 >rod
 >
 >--
 >Rod Bonfiglioli, Waite Agricultural Research Institute,
 >University of Adelaide, South Australia.
 >e-mail rbonfigl@waite.adelaide.edu.au

Bye
----------------------------------------------------------------------------
Eric Geerdes         x48927 /x48560 * To keep a snorer from snoring...
Biology Computer Services/MILL      * When snorer sleeps, put whipped cream
UCSD                                * in their hand--then tickle their face.
----------------------------------------------------------------------------

From owner-software@net.bio.net Thu Apr 08 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!zaphod.mps.ohio-state.edu!pacific.mps.ohio-state.edu!ohstpy!miavx1!miamiu!fdong
From: FDONG@MIAMIU.BITNET
Newsgroups: bionet.software
Subject: ARE THERE ANY METHODS TO DOWNLOAD A FILE FROM GCG?
Message-ID: <93098.162556FDONG@MIAMIU.BITNET>
Date: 8 Apr 93 20:25:56 GMT
References: <2586@emoryu1.cc.emory.edu>
Organization: Miami University - Miami Computing and Information Service
Lines: 7


  HELLO, NETTERS;
      CAN ANYONE TELL ME HOW TO DOWNLOAD A FILE FROM GCG OR FROM THIS SYSTEM?
 I TRY TO DOWNLOAD A FILE FROM GCG AND PRINT IT ON THE LP-PRINT , BOTH ARE NOT
 DONE. ANY INFORMATION IS HIGHLY APPRECIATED.

 FROM FDONG@MIAMIU.ACS.MUOHIO.EDU.

From owner-software@net.bio.net Thu Apr 08 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!wupost!howland.reston.ans.net!newsserver.jvnc.net!synapse.bms.com!riversend.bms.com!user
From: Roberts_D@BMS.COM (Dan Roberts)
Newsgroups: bionet.software
Subject: SEQApp Program Questions-Help Needed-
Message-ID: <Roberts_D-090493080143@riversend.bms.com>
Date: 9 Apr 93 12:08:32 GMT
Sender: news@synapse.bms.com
Followup-To: bionet.software
Organization: Bristol-Myers-Squibb Research
Lines: 17


 I have just gotten a copy of SEQAPP and I am having trouble setting up the
mail set up addresses.  I guess in the Box labeled "Your Mail address' I
would put <Roberts_D@BMS.COM>

In the Send Mail host box I would put <cliff.bms.com>
and in the Post-Office user@Host  I have no Idea what to put!!..And what is
the postoffice pswd???

I asked our computer network guru and he didnt know either...Can anybody
help me out???..Thanks.Dan

Dan Roberts
BRISTOL-MYERS-SQUIBB PHARM. RES. CENTER
Cardio-Vascular Biochem Dept.
PRINCETON, NEW JERSEY U.S.A. PLANET EARTH, MILKY-WAY GALAXY
<<<<INTERNET ADDRESS>>>>Roberts_D@BMS.COM

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!uunet!zaphod.mps.ohio-state.edu!uwm.edu!linac!att!princeton!tcp9kip37.princeton.edu!Gould
From: Gould@pucc.princeton.edu (Grant Gould)
Newsgroups: bionet.software
Subject: BIOLAB BBS
Message-ID: <1993Apr9.145051.1659@Princeton.EDU>
Date: 9 Apr 93 14:50:51 GMT
Sender: news@Princeton.EDU (USENET News System)
Organization: none
Lines: 5
X-Xxmessage-Id: <A7EB05355A011C25@tcp9kip37.princeton.edu>
Originator: news@nimaster
X-Xxdate: Fri, 9 Apr 93 10:49:25 GMT
Nntp-Posting-Host: tcp9kip37.princeton.edu
X-Useragent: Nuntius v1.1.1d17

Hey, I've got a piece of literature here that claims there's a BIOLAB BBS
at biolab.bio.ilstu.edu login as newuser.  Yet NCSATelnet claims it
doesn't exist.  The sysop (sysop@biolab.bio.ilstu.edu) doesn't exist
according to Pegasus.  Can anyone give me a hint in this direction?  Is
Biolab bbs down for some reason?

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!kristoff
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.software
Subject: Re: The Entrez CD-ROM and the Government Printing Office (US)
Message-ID: <Apr.9.21.25.26.1993.15738@net.bio.net>
Date: 10 Apr 93 04:25:27 GMT
References: <rhughes.40.0@ucsd.edu>
Organization: BIOSCI International Newsgroups for Biology
Lines: 47

rhughes@ucsd.edu (Richard J. Hughes) writes:

>Has anyone else been having trouble ordering the Entrez CD-ROM from the US 
>Government Printing Office?  I have had plenty of difficulty.

>I initially faxed an order, waited, received no response and faxed a 
>query.  Still no reponse.  Thanks to help from the Net, I managed to locate 
>their voice telephone number.  I had in fact sent the faxes to the correct 
>telephone number but they had been ignored because they didn't include a 
>check (?...but that's what they said).  I wonder why they even have a FAX 
>number.

>When you call the Gov't Printing Office, you are put on hold for a long 
>time. When someone finally answers, the audio is so faint as to be almost 
>indiscernable (maybe 5 dB above background).  I and one of our secretaries 
>have called them on four separate occasions and have made very little 
>headway.  The audio always borders on the inaudible and whoever you speak to 
>passes the buck (and you) to someone else.  You can just tell that they
>aren't interested in selling you this CD-ROM.

>Turns out that they won't send out the goods without prepayment.  UCSD 
>P.O.'s aren't good enough.  But UCSD can't generate a P.O. number without an 
>invoice.  The Gov't printing office doesn't want to send invoices without 
>the goods.  Catch 22.

>**<<flame on>>**
>It ticks me off that I'm paying taxes to support these bozos in a job 
>that they don't give a damn about.
>**<<flame off>>**

>Maybe the best thing to do is not to order from them.  That way maybe the 
>Gov't won't be able to justify paying all those bozos to jerk us around.

>Richard


Tsk, tsk (silence).  This is doubly sad because Yuki Abe who worked
very hard in her former role handling GenBank orders at IG is now out
looking for a job .... such are the ways of the world 8-(.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net


From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!kristoff
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.software
Subject: Re: The Entrez CD-ROM and the Government Printing Office (US)
Message-ID: <Apr.9.22.02.33.1993.18935@net.bio.net>
Date: 10 Apr 93 05:02:33 GMT
References: <rhughes.40.0@ucsd.edu> <rhughes.42.0@ucsd.edu>
Organization: BIOSCI International Newsgroups for Biology
Lines: 51

rhughes@ucsd.edu (Richard J. Hughes) writes:

>It turns out that the staff at NCBI are totally unlike those at the GPO.  I 
>received an e-mail response to the above net message from Dennis at NCBI the 
>same day.  Next morning, Rose Marie called and this morning I received a 
>Fed Ex package containing a copy of Entrez.  Wow!  Thanks guys.

>The folks who work at NCBI are clearly a different breed than those who work 
>at GPO.  I should have known that already, I guess.  Greg Schuler 
>promptly sent me a copy of the manual for his fantastic MACAW program.  All 
>I had to do was ask.

>Richard J. Hughes

I have the highest regards for Dennis Benson and others at NCBI.  They
have many talented people working there and Dennis has been a personal
friend for over five years.

I also want to point out one small fact in your statement above:


> I received an e-mail response to the above net message
                                             ***

While the GenBank contract was ebbing away, I stood up repeatedly at a
number of GenBank advisor meetings and argued that all major
government-sponsored projects should have an associated newsgroup to
ensure that they remain responsive to the public.  This advice did not
always fall on sympathetic ears .......

You have just provided **yet another** example of why this remains
true, and why the network has such an important role to play in
biology.

The next time that someone tries to tell you that the BIOSCI
newsgroups are full of worthless garbage, please be sure to remind
them of your experience.  I think that we can put up with the
occasional flame wars and sometimes bruised egos in exchange for the
benefits like this.  I survived five years of public potshots first as
manager of the BIONET National Computer Resource for Molecular Biology
and later as GenBank Manager, and I believe that others can too.
Posters should be civil, of course, and I have always advocated
contacting the private help addresses before going public, but the
newsgroups can serve as a forum when other routes fail.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!pipex!uunet!cs.utexas.edu!cactus.org!wixer!pagesat!news.cerf.net!network.ucsd.edu!sdcc12!jeeves!ericg
From: ericg@jeeves.ucsd.edu (Eric Geerdes)
Newsgroups: bionet.software
Subject: Re: Looking for the program Gene Jockey.  Thanks!
Summary: Here's a sample of responses...  Thanks again folks!
Keywords: gene, jockey, mac
Message-ID: <47604@sdcc16.Tcsd.edu>
Date: 9 Apr 93 15:55:44 GMT
References: <47549@sdcc12.ucsd.edu>
Sender: news@sdcc12.ucsd.edu
Lines: 73
Nntp-Posting-Host: jeeves.ucsd.edu

*******************************************************************

Here is a sample of the responses to my post.  What a Group!...

*******************************************************************

At  1:15 PM 4/8/93 -0400, Doug.Eernisse@um.cc.umich.edu wrote:
 >Eric,
 > It is commercial but I believe there is a partly functional
 >demo version around. Have you checked ftp.bio.indiana.edu in
                                        ^^^^^^^^^^^^^^^^^^^
 >the /molbio/mac directory? It is fast and has some interesting
 >capabilities as I recollect.
 > 
 >Doug Eernisse

**********************************
THE DEMO IS THERE JUST AS HE SAID.
**********************************

At  3:23 PM 4/9/93 +0200, Kirk Schnorr wrote:
 >I have used GeneJockey and have found it to be one of the best integrated
 >DNA analysis program I have worked with.  It is available from an English
 >software firm called Biosoft, 22 Hills Road Cambridge, CB2 1JP
 >I am surprized no one has mentioned the package until now.  One reason may
 >be that you have to pay for it.  If I recall it is about 500 German marks.
 > They will send a demo version if asked.  The demo version is the best way
 >to assess the program.
 >
 >Kirk SCHNORR
 >...

At 10:17 AM 4/9/93 -0400, genecodes@aol.com wrote:
 >Hi Eric,
 >...
 >If you are looking for Mac software, you should take a look at Sequencher
 >from Gene Codes.  I know there are some people at UCSD who are doing
 >a reasonable ammount of DNA sequencing. ... There was a short review of
 >Sequencher in the December issue of MacWorld (p. 274).  
 >
 >Send me your surface mail address and I'll see that someone sends you a
 >demo kit.  Sequencher is not as broad an application as Gene Jockey or 
 >the GCG package on the Vax, but it covers sequencing technology in depth,
 >is extremely well designed and easy to use, and is technically way ahead 
 >of the other commercial packages on the market.
 >...
 >Howard Cash
[ contact genecodes@aol.com for more info ]

At  1:31 PM 4/9/93 +0948, Rod Bonfiglioli wrote:
 > >...
 >  the prograsm is mareketed by a firm in cambridge, UK.  the firm will send 
you
 >a crippled demo that is absolutely useless and wont really show you anything the
 >program will do,.  i got a copy of this crippled demo disk, and got very little
 >idea what the program would do, so i didnt bother buying it.  best of luck
 >though.  if no-one else on the net sends you the adress of the firm (i cant
 >think of it off the top top top of my head...) get back to me and i will find
 >the address for you.
 >
 >rod
 >
 >--
 >Rod Bonfiglioli, Waite Agricultural Research Institute,
 >University of Adelaide, South Australia.
 >e-mail rbonfigl@waite.adelaide.edu.au

Bye
----------------------------------------------------------------------------
Eric Geerdes         x48927 /x48560 * To keep a snorer from snoring...
Biology Computer Services/MILL      * When snorer sleeps, put whipped cream
UCSD                                * in their hand--then tickle their face.
----------------------------------------------------------------------------

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!NET.BIO.NET!web!ingen.cu!scorpio.cu!carmas
From: web!ingen.cu!scorpio.cu!carmas@NET.BIO.NET (Carlos I. Armas)
Newsgroups: bionet.software
Subject: ftruncate() function?
Message-ID: <9304090203.AA06071@scorpio.cu>
Date: 9 Apr 93 02:03:58 GMT
Sender: daemon@net.bio.net
Reply-To: carmas%ingen@web.apc.org
Distribution: bionet
Organization: Center of Genetic Engineering & Biotechnology
Lines: 12

hi all!
I would appreciate if somebody tell me which function performs in 
UNIX ISC 3.0 ( C language) the same task than ftruncate() on UNIX BSD.
any suggestion or advise will be welcome.
thanks in advance!
carlos

-- 
 carlos armas         email: carmas%ingen@web.apc.org
 network manager                  automation division 
  center of genetic  engineering  &  biotechnology       
 p.o.box 6162                            havana, cuba

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!kristoff
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.software
Subject: Re: bionet.miscellaneous
Keywords: progress, productive, elegant
Message-ID: <Apr.9.21.04.38.1993.15464@net.bio.net>
Date: 10 Apr 93 04:04:38 GMT
References: <darrenp.733377699@dibbler.cs.monash.edu.au> <1993Mar29.085959.18390@comp.bioz.unibas.ch>
Organization: BIOSCI International Newsgroups for Biology
Lines: 35

doelz@comp.bioz.unibas.ch (Reinhard Doelz) writes:

>In article <darrenp.733377699@dibbler.cs.monash.edu.au>, darrenp@dibbler.cs.monash.edu.au (Daz) writes:
>|> I propose we rename this newsgroup to somehting like bionet.misc or
>|> bionet.irrelevant.
>|> 

>I agree that it would be good to have a better 'sorted' environment. 
>In particular, the following interest groups could be valuable if 
>we can only afford running them :

>bionet.software.avail		- those for asking for and discussing
>                                               availability, 
>                                  as well as announcing software
>                                  * MODERATED * 
>bionet.software.system          - general inquiries how to manage 
>                                               biocomputing sw

>bionet.software.misc            - all other stuff not fitting to the
>                                     other bionet.software newsgroups. 


>In particular, a group which discusses availability issues is most 
>needed in my view, and should be moderated. If this thread gets enough 
>discussion we could dare to raise a call for discussion on it. 

Seems like this thread died out after a few messages.  If someone
wants to put together a formal proposal, I'll be waiting.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net

From owner-software@net.bio.net Fri Apr 09 23:00:00 1993
Path: biosci!uwm.edu!wupost!emory!sol.ctr.columbia.edu!ira.uka.de!news.belwue.de!softserv.zdv.uni-tuebingen.de!studserv!zxmkr08
From: zxmkr08@studserv.zdv.uni-tuebingen.de (Cornelius Krasel)
Newsgroups: bionet.software
Subject: Re: BIOLAB BBS
Message-ID: <zxmkr08.734467658@studserv>
Date: 10 Apr 93 18:47:38 GMT
References: <1993Apr9.145051.1659@Princeton.EDU>
Organization: InterNetNews at ZDV Uni-Tuebingen
Lines: 100
NNTP-Posting-Host: studserv.zdv.uni-tuebingen.de

In <1993Apr9.145051.1659@Princeton.EDU> Grant Gould <Gould@pucc.princeton.edu> writes:

>Hey, I've got a piece of literature here that claims there's a BIOLAB BBS
>at biolab.bio.ilstu.edu login as newuser.  Yet NCSATelnet claims it
>doesn't exist.

NCSA Telnet is right :-)

With a little help of nslookup, I found that there is a domain ilstu.edu.

It contains the following subdomains:
> ls ilstu.edu
[rs6000.cmp.ilstu.edu]
Host or domain name            Internet address
 ilstu                          server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 ilstu                          server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 ilstu                          server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 ilstu                          138.87.1.2
 uh                             server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 uh                             server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 uh                             server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 smtplink                       138.87.1.111
 aca                            server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 aca                            server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 aca                            server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 phy                            server = protein.phy.ilstu.edu
 protein                        138.87.129.3
 phy                            server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 phy                            server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 phy                            server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 phy                            138.87.129.4
 math                           server = spider.math.ilstu.edu
 spider                         138.87.132.21
 math                           server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 math                           server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 math                           server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 ir                             server = rs6000.cmp.ilstu.edu
 rs6000                         138.87.1.2
 ir                             server = uxc.cso.uiuc.edu
 uxc                            128.174.5.50
 ir                             server = iugate.ucs.indiana.edu
 iugate                         129.79.1.9
 it                             server = rs6000.cmp.ilstu.edu
 rs6000                 