From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!bcm!jpower
From: jpower@kiwi.imgen.bcm.tmc.edu (Joanna L. Power)
Newsgroups: bionet.molbio.gdb,bionet.software
Subject: GDB frontend software
Keywords: gdb x interface
Message-ID: <211pon$erq@gazette.bcm.tmc.edu>
Date: 2 Jul 93 17:03:19 GMT
Organization: Molecular Biology Information Resource, Baylor College of Medicine, Houston, Tx
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Originator: jpower@kiwi.imgen.bcm.tmc.edu


Is anyone out there successfully using the gdb frontend software
on xterms?  I am having a bizarre problem with the DISPLAY variable.
First, DISPLAY must be set as an IP address instead of as a machine
name.  I can handle that.  The second problem is more troublesome,
as our goal is to set this up for users who may be intimidated by
the process in general.

The problem:  After I set DISPLAY in the initialization script, 
the user must still select "Change Terminal Environment" from the 
main menu, then "Change $DISPLAY Variable" from the next menu.   The
variable I set in the initialization script is there as the default,
but it is not actually set until the user accepts it.

My goal is to arrange it so that the user does not have to navigate
through these menus merely to hit return and accept the proper value
for DISPLAY.

Any ideas?  Please feel free to reply be e-mail if this request does
not seem of general enough interest.


--
Joanna Power

Genome Center Informatics Core	|	jpower@bcm.tmc.edu
Baylor College of Medicine	|	
1 Baylor Plaza			|	voice: 713-798-4689
Houston, TX 77030		|  	  fax: 713-798-5386	

 

-- 

--
Joanna Power

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!daresbury!news!ajb
From: ajb@s-crim1.dl.ac.uk (Alan Bleasby)
Newsgroups: bionet.software
Subject: Re: Molecular Weight search software wanted
Message-ID: <AJB.93Jul2170907@s-crim1.dl.ac.uk>
Date: 3 Jul 93 00:09:07 GMT
References: <1993Jun30.165111.27075@comp.bioz.unibas.ch>
Distribution: bionet
Organization: SERC Daresbury Laboratory, Warrington, UK
Lines: 759
NNTP-Posting-Host: s-crim1.dl.ac.uk
In-reply-to: doelz@comp.bioz.unibas.ch's message of Wed, 30 Jun 1993 16:51:11 GMT

Reinhard asked a question about molecular weight searching.
Such software is available on the UK EMBnet node and will be made
available via an email server in the next few days. I append a
software description below. Details of the software can be found in the
last issue of Current Biology

Rgds

Alan Bleasby
?RC Daresbury Laboratory
Warrington WA4 4AD
UK

Daresbury is the UK EMBnet national node.



				MOWSE MANUAL

				Version 1.0
	
			D.J.C.Pappin and A.J.Bleasby



	[1] Introduction:

	[2] Construction of the MOWSE database.

		[2.1] Source database.
		[2.2] Calculation of Molecular weight fragments.
		[2.3] MOWSE database structure.
		[2.4] The MW primary fragment molecular weight file.
		[2.5] The MDX file OWL entry index.
		[2.6] The SMW whole sequence molecular weight file.
		[2.7] Program Requirements.
		[2.8] MOWSE Scoring scheme.
		[2.9] Simulation studies.

	[3] References.

	[4] Running database searches.

		[4.1] Mw data file.
		[4.2] Running the program.

	[5] Results listing.

		[5.1] Specified search parameters.
		[5.2] Short 'hit' listing.
		[5.3] Detailed 'hit' listing.
		[5.4] Example of output listing.

[1] Introduction:

Determination of molecular weight has always been an  important aspect
of the characterization  of  biological  molecules.  Protein molecular
weight data, historically  obtained by SDS  gel electrophoresis or gel
permeation chromatography,  has  been used to establish purity, detect
post-translational    modification   (such   as   phosphorylation   or
glycosylation) and  aid identification. Until just over a decade  ago,
mass  spectrometric  techniques  were  limited  to   relatively  small
biomolecules, as proteins and nucleic acids were too large and fragile
to  withstand  the  harsh  physical   processes  required  to   induce
ionization.   This  began  to change with the  development  of  'soft'
ionization   methods  such  as   fast   atom   bombardment   (FAB)[1],
electrospray   ionisation  (ESI)   [2,3]  and  matrix-assisted   laser
desorption  ionisation  (MALDI)[4],  which  can  effect  the efficient
transition of large macromolecules from solution or  solid crystalline
state into  intact, naked molecular ions in the gas phase. As an added
bonus to the protein chemist, sample handling requirements are minimal
and the amounts required  for MS  analysis  are in the same range,  or
less, than existing analytical methods.

As well as providing  accurate mass information  for intact  proteins,
such techniques have been  routinely used  to produce accurate peptide
molecular  weight  'fingerprint'  maps  following  digestion of  known
proteins with specific proteases.  Such maps have been used to confirm
protein  sequences (allowing the  detection of errors  of translation,
mutation or insertion), characterise post-translational  modifications
or processing events and assign disulphide bonds [5,6].

Less well appreciated, however, is  the  extent to which  such peptide
mass information  can  provide a 'fingerprint' signature  sufficiently
discriminating to  allow  for the unique and rapid  identification  of
unknown sample proteins, independent of  other analytical methods such
as protein sequence analysis.

The following  text describes the construction and development of  the
MOWSE peptide mass database (for MOlecular Weight SEarch)  at the SERC
Daresbury  Laboratory.  Practical experience  has  shown  that  sample
proteins  can   be  uniquely   identified  using  as  few   as   3-  4
experimentally  determined  peptide  masses when  screened  against  a
fragment database  derived  from  over  50,000 proteins.  Experimental
errors  of a  few  Daltons  are tolerated by  the  scoring algorithms,
permitting the use of inexpensive  time-of-flight  mass spectrometers.
As  with other  types of physical data, such as amino acid composition
or linear  sequence,  peptide masses  can clearly  provide  a  set  of
determinants sufficiently  unique to  identify or match unknown sample
proteins. Peptide mass  fingerprints  can prove  as discriminating  as
linear peptide sequence, but can be obtained in a fraction of the time
using  less  material.   In  many  cases,  this  allows  for  a  rapid
identification  of a  sample  protein  before  committing  to  protein
sequence   analysis.   Fragment   masses   also   provide   structural
information, at  the protein level, fully complementary to large-scale
DNA sequencing or mapping projects [7,8,9].

[2] Construction of the MOWSE database.

[2.1] Source database.

MOWSE  was  created  from  the  OWL  non-redundant  composite  protein
sequence  database [10,11]. The latest release (version 18.1) contains
51,093 protein entries (comprising  some 15,956,287 residues), derived
from:

                                     	Residues       Entries
	
SWISSPROT Rel 22              	         25044     	8375696	   
NBRF Rel 33(PIR 1)          		   942       	 374576	   
NBRF Rel 33(PIR 2)      	      	  4660      	1122905	   
NBRF Rel 33(PIR 3)           	 	  7688      	2200541
GenBank Rel 72               		  8200      	2601590	   
NRL_3D Rel 9 (June 1992) 		  1352      	 224520	   


[2.2] Calculation of Molecular weight fragments.

For each  entry in  the source OWL database, MOWSE derives both  whole
sequence molecular weight and calculated peptide molecular weights for
complete  digests using the  range  of  cleavage  reagents  and  rules
detailed in Table 1. Cleavage  is disallowed if the target residue  is
followed by proline (except for CNBr  or Asp N).   Glu C (S. aureus V8
protease) cleavages  are also  inhibited  if  the adjacent  residue is
glutamic acid.  Peptide mass calculations  are  based  entirely on the
linear sequence  and use the average isotopic  masses  of amide-bonded
amino acid residues (IUPAC 1987 relative atomic  masses). To allow for
N-terminal  hydrogen and  C-terminal  hydroxyl  the  final  calculated
molecular weight of a peptide of N residues is given by the equation:

	    N
               S residue mass + 18.0153
	  n=1

Molecular weights  are rounded  to the nearest  integer  value  before
being entered into  the database. Cysteine residues are  calculated as
the free thiol, anticipating that  samples are  reduced  prior to mass
analysis.  CNBr  fragments  are calculated as  the homoserine  lactone
form.  Information  relating   to  post-   translational  modification
(phosphorylation,  glycosylation   etc.)   is  not  incorporated  into
calculation of peptide masses.
 
				
   Reagent no.	Reagent			Cleavage rule	    Total peptides 

	1	Trypsin			C-term to K/R		1711729
	2	Lys C			C-term to K		922337
	3	Arg C			C-term to R		835392
	4	Asp N			N-term to D		835002
	5	Glu C (Bicarbonate)	C-term to E		915708
	6	   "     (Phosphate)	C-term to E/D		1793285
	7	Chymotrypsin		C-term to F/W/Y/L/M	3047947
	8	CNBr			C-term to M		392924

	Table 1: Cleavage reagents modelled by MOWSE.

[2.3] MOWSE database structure.

The database consists of three binary files:

i) MOWSE.MW 		The primary file containing the fragment 
			molecular weights.

ii) MOWSE.MDX 		Index file relating OWL identifier codes 
			to the molecular weight information 
			in the primary Mw file.

iii) MOWSE.SMW		Calculated molecular weights of intact OWL 
			sequences.

The  query program accesses the  binary information transparently from
the  user  viewpoint.  In  the internal  representation the  molecular
weight  (and  other) integers are stored  as 4-byte  machine  specific
quantities. The  binary files  can be transferred  between machines of
the same 'endian' nature, but 'cross-endian' transfer is not possible.
The MOWSE  software  allows recreation  of  the  files on any platform
supporting a  standard  C language compiler.  The organisation of  the
database files is described below.

[2.4] The MW primary fragment molecular weight file.

Fragment molecular weight entries in this file map sequentially to the
order  of entries within the source (OWL) protein sequence file.  Each
MW file entry consists of 4 blocks and are shown below. The MW entries
are catenated.

			
	Block 1	OWL Entry Code	20 bytes
	Block 2	OWL Title Line	80 bytes
	Block 3	Reagent Table	80 bytes
	Block 4	Reagent 1	4 byte
		Reag
From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!redid.org.do!indotec!frichard
From: indotec!frichard@redid.org.do ("Frank Richardson")
Newsgroups: bionet.software
Subject: looking for algae culture media software
Message-ID: <2c344ad0._indotec@indotec.redid.org.do>
Date: 2 Jul 93 15:29:09 GMT
Sender: daemon@net.bio.net
Reply-To: "Frank Richardson"  <indotec!frichard@redid.org.do>
Distribution: bionet
Lines: 19

--------------------
Is there any  software available (database) that allow me to find
specific culture media for algae. The software should be able to run on 
IBM compatibles. I need it in order to find a selective culture media
for Chroococcus sp., an sphaerical non colonial blue green.

					Frank




Frank Richardson                      Phone  : (809) 566-8121 (ext 264)
indotec!frichard@redid.org.do	      Home   : (809) 596-6801   
				      Fax    : (809) 540-2808 or 2809
				      Address: INDOTEC, attn: Frank Richardson 
						P.O. Box 329-2, Sto. Dgo.
						DOMINICAN REPUBLIC

				

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: Sebastian.Bunka@vu-wien.ac.at (Bunka Sebastian)
Newsgroups: bionet.software
Subject: RE: database for clones
Message-ID: <1993Jul2.131719.15700@gserv1.dl.ac.uk>
Date: 2 Jul 93 12:43:31 GMT
Sender: I102PC1@at.ac.vu-wien.edvznovell2
Distribution: bionet
Organization: Vet.Med.Uni Wien
Lines: 51
Original-To: bio-soft@uk.ac.daresbury
Priority: normal
X-Mailer: WinPMail v1.0 (R1)

>Newsgroups: bionet.software
>Path: 
alijku05!alijku11!news.univie.ac.at!paladin.american.edu!howland.resto
n.ans.net!sol.ctr.columbia.edu!news.columbia.edu!cubmol!pw
>From: pw@cubmol.bio.columbia.edu (Paul Wakenight)
>Subject: database for strains, etc?
>Message-ID: <1993Jun29.000050.2164@news.columbia.edu>
>Sender: usenet@news.columbia.edu (The Network News)
>Nntp-Posting-Host: cubmol.bio.columbia.edu
>Organization: Columbia University, Dept. of Biological Sciences.
>Distribution: bionet.software
>Date: Tue, 29 Jun 1993 00:00:50 GMT
>Lines: 8

>Is there any software available ( database ) that would allow one to
>keep track of cell lines, etc. etc.

>Thanks much.


>Paul

there are some good PD programs available:

FTP   felix.embl-heidelberg.de  somewhere in PUB/MSDOS

filename             dnaclone.uaa
update               16-Mar-1990
version              1.1
size                 190 k
compressed           PAK
ASCII conversion     UUE (split; 3 parts: .UAA to .UAC)
author               Roy T. K.
description          Management of clones, strains, libraries etc. 
databases
literature           CABIOS 5 (1989), 321-322

an other file is clones.uaa...

If you need a copy, I can send it to you by e-mail file attachment ...

ps. you need the uudecode programs !
SB

+------------------------------------------------------------------+
|Dr. Sebastian Bunka      Email: Sebastian.Bunka@vu-wien.ac.at     |
|Inst.f.Bakteriologie                                              |
|Vet.Med.Uni Wien         Phone: +43-1-71155/261                   |
|Linke Bahngasse 11       Fax:   +43-1-71 49 110                   |
|A-1030 Wien                                                       |
+------------------------------------------------------------------+

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: JRAMON@mvax.fmed.uam.es
Newsgroups: bionet.software
Subject: Re: Digital Signature Standard
Message-ID: <1993Jul2.094024.11798@gserv1.dl.ac.uk>
Date: 2 Jul 93 11:41:00 GMT
Sender: list-admin@daresbury.ac.uk
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Comments: Pasarela de correo electronico local Internet<->DECnet de la UAM

With respect to the problem of the Digital Signature Standard, while it
concerns mainly the USA (.gov and .people), I'd like to add some comments
of my own.

	First, I'm not too literate on encription algorithms, neither
the legal issues concerning them abroad the USA. But may this affect me,
it interests me.

>...
>Several years ago, Congress directed the NIST (National Institute of
>Standards and Technology, formerly the National Bureau of Standards)
>to choose a single digital signature algorithm as a standard for the
>US.
>
>In 1992, two algorithms were under consideration.  One had been
>developed by NIST with advice from the NSA (National Security Agency),
>which engages in electronic spying and decoding.  There was widespread
>suspicion that this algorithm had been designed to facilitate some
>sort of trickery.
>
>The fact that NIST had applied for a patent on this algorithm
>engendered additional suspicion,...

	IMHO, governments shouldn't interfere with individual rights,
but if they must guarantee them they must have the right to *some times*
***violate*** them (e.g. depriving criminals of liberty). It is the
role of the people to control the government so that it doesn't make
bad use of its powers.

	However, there still remains the moral issue of what happens
when the gov. is stronger than the people. For instance in many
underdevelopped countries *ultimately owned* by another country or
commercial company.

>...
>On June 8, NIST published a new plan which combines the worst of both
>worlds: to adopt the suspect NIST algorithm, and give PKP, Inc. an
>*exclusive* license to the patent for it.  This plan places digital
>signature use under the control of PKP through the year 2010.
>...

	And this is even more appealing. I can never trust a private
company. You can't often trust the public institutions (or politics),
but they are -in democratic countries- under your control. You can't
in any way direct the personal politics of a private party. Which is
the same to say as that you are *absolutely* in their hands and can only
relay in their *good volunteer* if such a thing can be expected from
anyone that works only for his/her own interest. And were it such good-
ness, you must take into account other third parties. Any entity
whose life is threatened by another one will use anything at its reach
to defend itself, i.e. a threatened company could chose to rise its
royalties as much as needed and charge any additional royalties it needed.

>...
> ** The following notice was published in the Federal Register, Vol.
>          58, No. 108, dated June 8, 1993 under Notices **
>
>National Institute of Standards and Technology
>
>Notice of Proposal for Grant of Exclusive Patent License
>
>This is to notify the public that the National Institute of
>Standards and Technology (NIST) intends to grant an exclusive
>world-wide license to Public Key Partners of Sunnyvale, California
 ==================
>to practice the Invention embodied in U.S. Patent Application No.
>07/738.431 and entitled "Digital Signature Algorithm."  A PCT
>application has been filed.  The rights in the invention have been
>assigned to the United States of America... 

(my underlining, some stuff deleted)

	More on the same, but now this not only affects the USA.
Since most USA standards become world standards, and since many under-
developed countries relay on US technologies, now the problem extends
to us all.

>Appendix "A"
>
>... some stuff deleted ...
>
>It is PKP's intent to make practice of the DSA royalty free for
 ============^^^^^^
>personal, noncommercial and U.S. Federal, state and local
>government use.  As explained below, only those parties who enjoy
>commercial benefit from making or selling products, or certifying
>digital signatures, will be required to pay royalties to practice
>the DSA.

	My underlining again. Aha! so all you (and maybe us) have
is a declaration of principles or intentions. Which in principle
sound quite well. But no assurance you won't get later surprises.
Let's see... Uh? Am I paranoic?...

	I remember the LZW compression algorithm issue. Wasn't too
enforced till it went a de-facto standard. Oh, and wasn't it similar
with the Backing-Store algorithm? Freely used in X-windows, which
was developed with public resources, until X became a standard -mainly
por its public accessibility-, and then after several years, the
patent comes suddenly into light! And what happened with the threats
to the Univ. of Wisconsin GCG package last summers? Wasn't it that
it was threatened because of commercial companys pressure on the
politicians or so?

>Having stated these intentions, PKP now takes this opportunity to
>publish its guidelines for granting uniform licenses to all parties
>having a commercial interest in practicing this technology:

	Well, well, all of them sound quite senseful. Do they?

>Fourth, PKP's royalty rates for the right to make or sell products,
>subject to uniform minimum fees, will be no more than 2 1/2% for
>hardware products and 5% for software, with the royalty rate
>further declining to 1% on any portion of the product price
>exceeding $1,000.  These royalty rates apply only to noninfringing
>parties and will be uniform without regard to whether the licensed
>product creates digital signatures, verifies digital signatures or
>performs both.

	Now if I want to make, say, a new program, using a few standards
for it to be useful, say I use encryption, I pay 5%, say I use X
with Backing-Store (which pays royalties), which draws an X-Or cursor
(which is also patented), and compresses the messages with LZ,
and uses a few other standard (or not) libraries... If I have to
pay 5% for each of these, I may end paying more royalties than
the cost of the final product.

	Quite senseful, isn't it? More yet since I'm not american,
and royalties could be greater, and I'd had to add import/export
royalties...

	Fine, what kind of programs can I write?

>Fifth, for the next three (3) years, all commercial services which
>certify a signature's authenticity for a fee may be operated
>royalty free.  Thereafter, all providers of such commercial
>certification services shall pay a royalty to PKP of $1.00 per
>certificate for each year the certificate is valid.

	Wow! I work in the academic world, but this sounds to me as
if a car factory using injection engines from other company were
granted a three-year use license. And each additional year *I* used
my car they had to pay an additional amount. This gets curiouser...

>Sixth, provided the foregoing royalties are paid on such products
>or services, all other practice of the DSA shall be royalty free.

	While the company doesn't decide to change politics...

>... more stuff deleted.

--------------

	Well, I can't say much for myself. If my country didn't invest
in developing these algorithms I agree I must pay. It is my duty to
enforce my politicians to fund research or else to restrict certain
patent application policies.

	But, the same holds for all of us. IMHO the solution NOW is
either to support additional research and develop a new algorithm
that could replace that standard being public, or either to try to
stop certain kinds of patent application which may derive in worst
use of public funds.

	IMHO, a gov. resource should be exploited by the gov. or 
only by a company that is it or its policies directly controlled
by the gov. I agree that govs. have right to develop their own anythings
and to exploit them.

	But I can't see any excuse for any public-dependent (i.e. non
fascist) goverment to give away -in full, in part or temporarily- all
the rights of public goodies to a private party, hence leaving the
public -which is the real owner of the good- at the hands of a private
and self-interested party.

			J. R. Valverde
		Biomedical Research Insitute
			Madrid - SPAIN

Disclaimed: the opinions depicted above are my own and only my own.
They do not necessary reflect the opinion of anyone else.

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: JRAMON@mvax.fmed.uam.es
Newsgroups: bionet.software
Subject: Fwd: Digital Signature Standard
Message-ID: <1993Jul2.085004.11189@gserv1.dl.ac.uk>
Date: 2 Jul 93 10:51:00 GMT
Sender: list-admin@daresbury.ac.uk
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From:	CCUAM2::IN%"info-gnu-request@prep.ai.mit.edu"  2-JUL-1993 06:11:38.65
To:	IN%"info-gnu@prep.ai.mit.edu"
CC:	
Subj:	Digital Signature Scandal

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Subject: Digital Signature Scandal
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[The following is an official announcement from the League for Programming
Freedom.  Please redistribute this as widely as possible.]


		   Digital Signature Scandal

Digital signature is a technique whereby one person (call her
J. R. Gensym) can produce a specially encrypted number which anyone
can verify could only have been produced by her.  (Typically a
particular signature number encodes additional information such as a
date and time or a legal document being signed.)  Anyone can decrypt
the number because that can be done with information that is
published; but producing such a number uses a "key" (a password) that
J. R. Gensym does not tell to anyone else.

Several years ago, Congress directed the NIST (National Institute of
Standards and Technology, formerly the National Bureau of Standards)
to choose a single digital signature algorithm as a standard for the
US.

In 1992, two algorithms were under consideration.  One had been
developed by NIST with advice from the NSA (National Security Agency),
which engages in electronic spying and decoding.  There was widespread
suspicion that this algorithm had been designed to facilitate some
sort of trickery.

The fact that NIST had applied for a patent on this algorithm
engendered additional suspicion; despite their assurances that this
would not be used to interfere with use of the technique, people could
imagine no harmless motive for patenting it.

The other algorithm was proposed by a company called PKP, Inc., which
not coincidentally has patents covering its use.  This alternative had
a disadvantage that was not just speculation: if this algorithm were
adopted as the standard, everyone using the standard would have to pay
PKP.

(The same patents cover the broader field of public key cryptography,
a technique whose use in the US has been mostly inhibited for a decade
by PKP's assiduous enforcement of these patents.  The patents were
licensed exclusively to PKP by the Massachusetts Institute of
Technology and Stanford University, and derive from taxpayer-funded
research.)

PKP, Inc. made much of the suspect nature of the NIST algorithm and
portrayed itself as warning the public about this.

On June 8, NIST published a new plan which combines the worst of both
worlds: to adopt the suspect NIST algorithm, and give PKP, Inc. an
*exclusive* license to the patent for it.  This plan places digital
signature use under the control of PKP through the year 2010.

By agreeing to this arrangement, PKP, Inc. shows that its concern to
protect the public from possible trickery was a sham.  Its real desire
was, as one might have guessed, to own an official national standard.
Meanwhile, NIST has justified past suspicion about its patent
application by proposing to give that patent (in effect) to a private
entity.

Instead of making a gift to PKP, Inc., of the work all of us have paid
for, NIST and Congress ought to protect our access to it--by pursuing
all possible means, judicial and legislative, to invalidate or annull
the PKP patents.  If that fails, even taking them by eminent domain is
better (and cheaper in the long run!) than the current plan.

You can write to NIST to object to this giveaway.  Write to:

Michael R. Rubin
Active Chief Counsel for Technology
Room A-1111, Administration Building,
National Institute of Standards and Technology
Gaithersburg, Maryland 20899
(301) 975-2803.

The deadline for arrival of letters is around August 4.

Please send a copy of your letter to:

League for Programming Freedom
1 Kendall Square #143
P.O.Box 9171
Cambridge, Massachusetts 02139

(The League for Programming Freedom is an organization which defends
the freedom to write software, and opposes monopolies such as patented
algorithms and copyrighted languages.  It advocates returning to the
former legal system under which if you write the program, you are free
to use it.  Please write to the League if you want more information.)

Sending copies to the League will enable us to show them to elected
officials if that is useful.



This text was transcribed from a fax and may have transcription
errors.  We believe the text to be correct but some of the numbers
may be incorrect or incomplete.

---------------------------------------------------------------------

 ** The following notice was published in the Federal Register, Vol.
           58, No. 108, dated June 8, 1993 under Notices **

National Institute of Standards and Technology

Notice of Proposal for Grant of Exclusive Patent License

This is to notify the public that the National Institute of
Standards and Technology (NIST) intends to grant an exclusive
world-wide license to Public Key Partners of Sunnyvale, California
to practice the Invention embodied in U.S. Patent Application No.
07/738.431 and entitled "Digital Signature Algorithm."  A PCT
application has been filed.  The rights in the invention have been
assigned to the United States of America. 

The prospective license is a cross-license which would resolve a
patent dispute with Public Key Partners and includes the right to
sublicense.  Notice of availability of this invention for licensing
was waived because it was determined that expeditious granting of
such license will best serve the interest of the Federal Government
and the public.  Public Key Partners has provided NIST with the
materials contained in Appendix A as part of their proposal to
NIST.

Inquiries, comments, and other materials relating to the prospec-
tive license shall be submitted to Michael R. Rubin, Active Chief
Counsel for Technology, Room A-1111, Administration Building,
National Institute of Standards and Technology, Gaithersburg,
Maryland 20899.  His telephone number is (301) 975-2803.  Applica-
tions for a license filed in response to this notice will be
treated as objections to the grant of the prospective license.  
Only written comments and/or applications for a license which are
received by NIST within sixty (60) days for the publication of this
notice will be considered.

The prospective license will be granted unless, within sixty (60)
days of this notice, NIST receives written evidence and argument
which established that the grant of the license would not be
consistent with the requirements of 35 U.S.C. 209 and 37 CFR 404.7.

  Dated:  June 2, 1993.

Raymond G. Kammer
Acting Director, National Institute Standards and Technology.

Appendix "A"

The National Institute for Standards and Technology ("NIST") has
announced its intention to grant Public Key Partners ("PKP")
sublicensing rights to NIST's pending patent application on the
Digital Signature Algorithm ("DSA").

Subject to NIST's grant of this license, PKP is pleased to declare
its support for the proposed Federal Information Processing
Standard for Digital Signatures (the "DSS") and the pending
availability of licenses to practice the DSA.  In addition to the
DSA, licenses to practice digital signatures will be offered by PKP
under the following patents:

          Cryptographic Apparatus and Method ("Diffie-Hellman")
                No. 4,200,770
          Public Key Cryptographic Apparatus and Method
		("Hellman-Merkle")   No. 4,315,552
          Exponential Cryptographic Apparatus and Method
                ("Hellman-Pohlig")   No. 4,434,414
          Method For Identifying Subscribers And For Generating
		And Verifying Electronic Signatures In A Data Exchange
                System ("Schnorr")   No. 4,995,082

It is PKP's intent to make practice of the DSA royalty free for
personal, noncommercial and U.S. Federal, state and local
government use.  As explained below, only those parties who enjoy
commercial benefit from making or selling products, or certifying
digital signatures, will be required to pay royalties to practice
the DSA.

PKP will also grant a license to practice key management, at no
additional fee, for the integrated circuits which will implement
both the DSA and the anticipated Federal Information Processing
Standard for the "key escrow" system announced by President Clinton
on April 16, 1993.

Having stated these intentions, PKP now takes this opportunity to
publish its guidelines for granting uniform licenses to all parties
having a commercial interest in practicing this technology:

First, no party will be denied a license for any reason other that
the following:

          (i)    Failure to meet its payment obligations,
          (ii)   Outstanding claims of infringement, or
          (iii)  Previous termination due to material breach.

Second, licenses will be granted for any embodiment sold by the
licensee or made for its use, whether for final products software,
or compfinal products software,
or components such as integrated circuits and boards, and regard-
less of the licensee's channel of distribution.  Provided the
requisite royalties have been paid by the seller on the enabling
component(s), no further royalties will be owned by the buyer for
making or selling the final product which incorporates such
components.

Third, the practice of digital signatures in accordance with the
DSS may be licensed separately from any other technical art covered
by PKP's patents.

Fourth, PKP's royalty rates for the right to make or sell products,
subject to uniform minimum fees, will be no more than 2 1/2% for
hardware p
From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!apldbio.com
From: james@apldbio.com (James Candlin)
Newsgroups: bionet.announce,bionet.biology.computational,bionet.software
Subject: Call for Computer Demonstrations
Message-ID: <514@biosys.apldbio.COM>
Date: 2 Jul 93 01:22:20 GMT
Sender: kristoff@net.bio.net
Reply-To: james@apldbio.com
Followup-To: bionet.announce
Organization: Applied Biosystems, Inc.
Lines: 231
Approved: bionews-moderator@net.bio.net
Xref: biosci bionet.announce:603 bionet.biology.computational:475 bionet.software:5378



                  Macromolecules, Genes, and Computers: Chapter Three
                         International Symposium and Workshop

                                August 17-22, 1993

                     Waterville Valley Resort and Conference Center
                           Waterville Valley, New Hampshire

Sponsored By:
        o       The BMERC of the College of Engineering,
                Boston University
        o       Applied Biosystems

Additional Sponsors:
    Digital Equipment Corporation
    DNA*, Inc.
    Genetics Computer Group
    Hitachi Software Engineering America, Ltd.
    IntelliGenetics, Inc.
    Molecular Simulations, Inc.
    Sun Microsystems, Inc.
    Sybase, Inc.


    There are a few openings  remaining  in  the  "Computational  Biology
Tools" computer demonstration workshop scheduled as part of this meeting.
If you wish to participate,  please  fill  in  and  return  the  attached
application form to Dawn Madden at Applied Biosystems (dawn@apldbio.com).


                        Symposium Philosophy

This international symposium and workshop has been designed to facilitate
the  exchange  of information in the interdisciplinary domain overlapping
computer science, mathematics, genetics, medicine, and molecular biology.
The  agenda has been planned to optimize this exchange through formal and
informal formats in an enjoyable mountain resort environment. The session
topics  have  been  chosen  to  direct discussions toward the fundamental
properties of biological systems; the  enabling  technologies;   and  the
anticipated   computational   challenges  within  this  interdisciplinary
domain.

                        Meeting Program Summary

Keynote Speaker: Stuart Kauffman, Santa Fe Institute


Computer Demonstration Workshops:

Participants wishing to demonstrate software must submit abstract, system
requirements, and whether  they  will  supply  their  own  equipment  for
demonstrations during workshops.

I. Computational Biology Resources

Represented resources  and  academic  centers  will  provide  "hands  on"
demonstrations  of  their computer software and databases.  Emphasis will
be on applications to the problems within the interdisciplinary domain of
the symposium.

II. Computational Biology Tools

Contributors  will  present  "hands  on"  demonstrations  of  specialized
software and hardware during this "electronic poster session". Associated
poster will describe current and future applications.


Tutorial Workshops:

I. Use of NCBI's Tools and Services
Organizer: Jim Ostell

II. Molecular Biology Overview for the Non-Molecular Biologist
Organizer: Bob Gross

III. An Overview of Computational Tools Useful to Molecular Biologists
Organizer: Dawn Madden

Discussion Workshops:

I. Converging on a sequence database format different packages could share
Organizer: Leslie Taylor

II. Linking Analytical Tools through Interprocess Communication
Organizers: Chris Sander and Pat Gillevet


Sessions:

Session 1 - Genome and Biotechnology Challenges
Organizers: Charles Cantor and Patrick Gillevet
Speakers: Chris Sander, B. Dujon, Sydney Brenner, Ben Koop, Michael 
          Waterman, Nat Goodman

Session 2 - Molecular Docking and Recognition: New Approaches and
            Remaining Challenges
Organizers: Steve Bryant and A. Keith Dunker
Speakers: L. Mario Amzel, Edward Dratz, Stephen Fodor, Terry Lybrand,
          Scott Dixon, Wayne Anderson

Session 3 - Aspects of RNA Structures and Their Analyses
Organizers: Michael Zuker and Jude Shavlik
Speakers: Robert Cedergren, David Bartel, Gary J. Olsen

Session 4 - Protein Structure Analyses and Prediction
Organizers: Jean Garnier and Timothy Havel
Speakers: J. Greer, Gordon Crippen, Robert Swendsen, Mark Rance     
          Nobuhiro Go, Jorge Navaza, Robert Bruccoleri,       
          Chris Sander, Jan Hermans

Session 5 - Gene Regulation: Representation, Modeling, and Generalization
Organizers: David Farb and John Reinitz
Speakers: Carl Parker, Nadia Rosenthal, David Sharp, Denis Thieffry,
          Alan P. Wolffe

Session 6 - New Artificial Intelligence and Computational Methods
Organizers: Richard Lathrop and Jude Shavlik
Speakers: David Haussler, Larry Hunter, David Searls

Session 7 - Biological Databases: Design and Function
Organizer: David Landsman
Speakers: Jim Ostell, Amos Bairoch, Bill Gelbart

-------------------------------------------------------------------------------

                     Meeting and Computer Workshop Application Form

Please return by July 9, 1993 to:  
Dawn Madden
Applied Biosystems
850 Lincoln Centre Drive
Foster City, CA 94404
FAX: 415-572-2743
Phone: 415-570-6667x8803
E-mail: dawn@apldbio.com

Registration Information

Name: [                                         ]
Title:[                                         ]
Sex: [ ] M   [ ] F

Institutional Affiliation: 
[                                                               ]

Address:
[                                                               ]
[                                                               ]
[                                                               ]
Phone: [(   )           ]
FAX:   [(   )           ] 
E-mail: [                               ]

Are you applying for travel support?   [ ] Yes    [ ] No

Housing and Meal Options

Please check your preference:

   [ ]      Conference fee-double occupancy         $485 per person
            (Includes conference registration fee, housing, meals and banquet)
            Indicate desired roommate, if known:
            [                                          ]

   [ ]      Conference fee-single occupancy         $600 per person 
            (Includes conference registration fee, housing, meals and banquet)

   [ ]      Housing only-for guests not attending conference     $300 per person            (Includes double occupancy housing only. All meals must be paid for
             separately.)

Please check banquet meal preference:  
[ ] Filet Mignon     [ ] Broiled Swordfish     [ ] Vegetarian 
        
Do you have any special housing or dietary needs? 
If so, please indicate their nature. 
  [                                                                           ]

Please mail a 10% deposit with hard copy of  this  form  in  addition  to
submitting the filled in form by electronic mail.  (Make check payable to
Applied Biosystems)

Signature [                                    ]  Date: [               ]


Equipment and Telecommunications Requirements for Computer Demonstration:


Computer Equipment You Will Provide:



Abstract 

Type a brief  abstract  of  your  anticipated  poster  session,  computer
application  workshop presentation, or current research activities in the
space below. All participants are expected  to  contribute  to  either  a
poster session or computer workshop.



Title:


Author(s):


Abstract:









---

James Candlin

------------------------------------------------------------------------
email:	james@apldbio.com		Applied Biosystems, Inc
phone:	+1 415 570 6667 x8742		850 Lincoln Centre Drive
fax:	+1 415 572 2743			Foster City
					CA 94404, USA
------------------------------------------------------------------------
				



From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!UVMVAX.UVM.EDU!D_CAMPBELL
From: D_CAMPBELL@UVMVAX.UVM.EDU
Newsgroups: bionet.software
Subject: Ordination software
Message-ID: <01H01HKWHE7O000AUD@uvmvax.uvm.edu>
Date: 2 Jul 93 01:26:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 8

I am looking for a current copy of ECOSURVEY, programes for the analysis
of ecological data, produced by T.J. Carleton (U. of Toronto). 
or copies of ordination - classifaction software (decorana/twinspan) that is 
IBM compatable.
			David L. Campbell
			(802) 655-6232 or 656-2930
			University of Vermont
 				

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!NCCCOT7.AGR.CA!EM609MBCPHL
From: EM609MBCPHL@NCCCOT7.AGR.CA
Newsgroups: bionet.software
Subject: DNASIS
Message-ID: <01H02KGT56WY005SNU@GW.AGR.CA>
Date: 2 Jul 93 20:05:38 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 10

I am interested in comments on the Sequence analysis packages
DNASIS and PROSIS, particularly as they compare to PC/GENE.
Please reply by email or to "methods-and-reagents".
I apologize for a questions which may have already been 
discussed. I did try a waismail search for DNASIS which
seemed to give a large volume of irrelevant material.
Thanks,
Pat Covello
Central Plant Health Lab
Agriculture Canada

From owner-software@net.bio.net Thu Jul 01 23:00:00 1993
Path: biosci!USAV01.GLAXO.COM!MJA12046%USA.decnet
From: MJA12046%USA.decnet@USAV01.GLAXO.COM ("USA::MJA12046")
Newsgroups: bionet.software
Subject: Gopher Hole for GBASE???
Message-ID: <9307021851.AA15181@net.bio.net>
Date: 2 Jul 93 19:35:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 9

Hi,
     Does anyone know of a way to access the GBASE (mouse genetic map data)
through Gopher?
thanks!

Mike Agostino
Glaxo, Inc.             
mja12046@usav01.glaxo.com


From owner-software@net.bio.net Sun Jul 04 23:00:00 1993
Path: biosci!uwm.edu!wupost!uunet!mcsun!news.funet.fi!funic!convex!harper
From: harper@convex.csc.FI (Rob Harper)
Newsgroups: bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
Subject: Re: Looking for xmosaic for VMS
Message-ID: <1993Jul5.144457.11025@nic.funet.fi>
Date: 5 Jul 93 14:44:57 GMT
References: <1993Jul5.092319.7229@mcclb0.med.nyu.edu>
Sender: usenet@nic.funet.fi
Organization: Finnish Academic and Research Network Project - FUNET
Lines: 21
Xref: biosci bionet.software:5388
Nntp-Posting-Host: convex.csc.fi

In <1993Jul5.092319.7229@mcclb0.med.nyu.edu> smith@mcclb0.med.nyu.edu writes:

>SO. If anyone knows where that port is, please re-post the FTP site address.  
>Thanks!

You can get xmosaic in various flovours from nic.funet.fi via anonymous ftp.


lrwxrwxrwx  1 root     funstaff       19 Jul  4 18:18 xmosaic-alpha.Z 
lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18 xmosaic-dec.Z 
lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18 xmosaic-ibm.Z 
lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18 xmosaic-sgi.Z 
lrwxrwxrwx  1 root     funstaff       25 Jul  4 18:18 xmosaic-sun-lresolv.Z 
lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18 xmosaic-sun.Z 

RGDS -=ROB=-
--
 Rob Harper                        E-mail:          harper@convex.csc.fi    
 Center for Scientific Computing   Molbio/software: harper@nic.funet.fi
 Tietotie 6, P.O. Box 405          Telephone:       +358 0 457 2076
 SF-02101 Espoo Finland            Fax:             +358 0 457 2302

From owner-software@net.bio.net Sun Jul 04 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!usc!cs.utexas.edu!rutgers!mcclb0.med.nyu.edu!smith
From: smith@mcclb0.med.nyu.edu
Newsgroups: bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
Subject: Looking for xmosaic for VMS
Message-ID: <1993Jul5.092319.7229@mcclb0.med.nyu.edu>
Date: 5 Jul 93 14:23:19 GMT
Organization: NYU Medical Center, New York, NY 10016, USA
Lines: 15
Xref: biosci bionet.software:5387


No more than 3 weeks ago someone posted an announcement of a port of 
'xmosaic' to VMS.  I immediately grabbed it and put it on my machine.  It 
works quite nicely.  However, the individual who did the port never put a 
signature anywhere (that I can find) in the documentation.  Consequently, I 
can not find the site where it came from. (I know, I know, it pretty stupid, 
but ...)

SO. If anyone knows where that port is, please re-post the FTP site address.  
Thanks!

+----------------------------------------------------------------------------+
|Ross Smith,  Research Computing Resource, Department of Cell Biology, NYU-MC|
|E-Mail:  SMITH@NYUMED.BITNET (BITNET),   SMITH@MCCLB0.MED.NYU.EDU (Internet)|
+----------------------------------------------------------------------------+

From owner-software@net.bio.net Mon Jul 05 23:00:00 1993
Path: biosci!parc!decwrl!ames!haven.umd.edu!uunet!pipex!uknet!nessie!v4.cgu.mcc.ac.uk!mzagsaa
From: mzagsaa@v4.cgu.mcc.ac.uk (Tony Arnold)
Newsgroups: bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
Subject: Re: Looking for xmosaic for VMS
Message-ID: <1993Jul6.091203.21639@nessie.mcc.ac.uk>
Date: 6 Jul 93 09:12:03 GMT
References: <1993Jul5.092319.7229@mcclb0.med.nyu.edu> <1993Jul5.144457.11025@nic.funet.fi>
Sender: mzagsaa@umrcc.cgu.mcc.ac.uk (Tony Arnold)
Reply-To: A.C.Arnold@mcc.ac.uk
Organization: Manchester Computing Centre
Lines: 45
Xref: biosci bionet.software:5390


In article <1993Jul5.144457.11025@nic.funet.fi>,
harper@convex.csc.FI (Rob Harper) writes:
|>Newsgroups:
|>bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
|>From: harper@convex.csc.FI (Rob Harper)
|>Subject: Re: Looking for xmosaic for VMS
|>Date: Mon, 5 Jul 93 14:44:57 GMT
|>
|>In <1993Jul5.092319.7229@mcclb0.med.nyu.edu>
|>smith@mcclb0.med.nyu.edu writes:
|>
|>>SO. If anyone knows where that port is, please re-post the FTP
|>site address.  
|>>Thanks!

Yes please!

|>
|>You can get xmosaic in various flovours from nic.funet.fi via
|>anonymous ftp.
|>
|>
|>lrwxrwxrwx  1 root     funstaff       19 Jul  4 18:18
|>xmosaic-alpha.Z 
|>lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18
|>xmosaic-dec.Z 
|>lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18
|>xmosaic-ibm.Z 
|>lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18
|>xmosaic-sgi.Z 
|>lrwxrwxrwx  1 root     funstaff       25 Jul  4 18:18
|>xmosaic-sun-lresolv.Z 
|>lrwxrwxrwx  1 root     funstaff       17 Jul  4 18:18
|>xmosaic-sun.Z 

These look like the files that NCSA distribute. To my understanding, they
are all Unix flavour implementation. NCSA does not have a VMS port, but
if someone has one, please let me know as I am keen to run this
stuff on our
aging VAXs.

Tony Arnold,
OpenVMS Systems Manager,
University of Manchester, UK.

From owner-software@net.bio.net Mon Jul 05 23:00:00 1993
Path: biosci!UCRVM2.BITNET!SMELGAR
From: SMELGAR@UCRVM2.BITNET
Newsgroups: bionet.software
Subject: components of variance question
Message-ID: <9307060028.AA26398@net.bio.net>
Date: 6 Jul 93 00:28:22 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 13

Could anybody please tell me which statistical package can I use to obtain comp
onents of variance of a hierarchical analysis of variance with one covariable?

  The main problem is that the analysis is unbalanced, therefore it is
 very difficult to obtain the estimates of components of variance by hand.

  I will appreciate any help.  My e-mail address is
  SMELGAR@UCRVM2

Thank you,
             Sergio Melgar
             Escuela de Biologia
             Universidad de Costa Rica

From owner-software@net.bio.net Mon Jul 05 23:00:00 1993
Path: biosci!uwm.edu!math.ohio-state.edu!darwin.sura.net!lhc!laputa!altschul
From: altschul@laputa.nlm.nih.gov (Stephen Altschul)
Newsgroups: bionet.software
Subject: Sequence Analysis Workshop
Message-ID: <1993Jul6.202230.9826@nlm.nih.gov>
Date: 6 Jul 93 20:22:30 GMT
Sender: news@nlm.nih.gov
Organization: National Library of Medicine
Lines: 95
X-Newsreader: Tin 1.1 PL4


********************************************************************************

                 WORKSHOP ON MOLECULAR SEQUENCE ANALYSIS
                        Hartley Conference Center
                    Mitchell School of Earth Sciences
                    Stanford University, Stanford, CA

                           August 5 - 6, 1993


                       THURSDAY:   AUGUST 5, 1993

Session I.      Protein Structure  (12:30 - 3:00)

        Chairman:  F. Cohen

        T. Smith            A Protein Core Structure Library and Its Use in
		            Nonhomologous Extension Modeling

        S. Bryant           A  Residue Contact Potential for Threading Protein
                            Sequence Through Folding Motif

        T. Lybrand          Generation of Three-Dimensional Protein Models
                            Using Computational Methods and Experimental Data

        C. Ring             Application of Homology-Built Structures

        J. Blaney           Conformationally Flexible Docking and Evolution of
                            Molecules to Fit a Binding Site of Known Structure.

Break - 45 minutes

Session II.  Sequence Alignment (3:45 - 7:15)

        Chairman:  M. Waterman

        C. Lawrence         Gibbs Free Energy and the Gibbs Sampler Converge to
                            Align Multiple Biopolymer Sequences

        D. Sankoff          Genomic Distances

        G. Stormo           Identifying Domains in RNA Composed of Sequence and
                            Structure
Break - 30 minutes

        G. Gonnet           (tentative)  The IMD Sequence Alignment Algorithm:
                            Theory and Practice

        S. Henikoff         Amino Acid Substitution Matrices without
                            Extrapolation

        V. Brendel          Score Statistics for Molecular Sequence Analysis


                       FRIDAY:  AUGUST 6, 1993

Session III.  Repeating Structures and Sequence Inhomogeneity (9:00 - 12:30)

        Chairman:  S. Karlin

        M. Calos            Evolution of Repeats and Transposable Elements from
                            Bacteria to Humans

        J. Jurka            Identification and Analysis of Human Interspersed
                            Repetitive Elements

        P. Green            Analysis of C. Elegans Genomic Sequence

Break - 30 minutes

        P. Pevzner          Genome Inhomogeneity and Overlapping Words Paradox

        G. Schachtel        Assessing Inhomogeneities in Long DNA Sequences

        D. States           TBA

Session IV.  Informal Presentations and Discussion (2:30 - 6:00)

        Chairman:  S. Altschul

Break - 4:30

There is no registration fee.  However, for those who need lodging,
dormitory rooms are available on the Stanford campus at $42.50 single and
$35.00 shared.  Those planning to attend and requiring a room are advised
to make a reservation as soon as possible by contacting Samuel Karlin.
Attendees with a reservation may pick up room keys at Elliot Program Center.
                     
		     Telephone          FAX                   email
                   --------------  --------------  ----------------------------
Samuel Karlin      (415) 723-2204  (415) 725-2040  fd.zgg@forsythe.stanford.edu
Fred Cohen         (415) 426-8519  (415) 476-6515  cohen@cgl.ucsf.edu
Michael Waterman   (213) 740-2408  (213) 740-2437  msw@hto.usc.edu
Stephen Altschul   (301) 496-2475  (301) 480-9241  altschul@nlm.nih.gov

From owner-software@net.bio.net Mon Jul 05 23:00:00 1993
Path: biosci!crunch.unm.edu
From: stanly@crunch.unm.edu (Stanly Steinberg)
Newsgroups: bionet.announce,bionet.software,comp.edu,sci.aeronautics,sci.bio,sci.bio.technology,sci.chem,sci.edu,sci.electronics,sci.energy
Subject: Symbolic Computing Short Course -- Advertisement
Summary: 3 day short course emphasizing Mathematica
Keywords: Computer Algebra, Symbol Manipulation, Mathematica
Message-ID: <21am70INNq4b@lynx.unm.edu>
Date: 6 Jul 93 01:57:52 GMT
Sender: kristoff@net.bio.net
Organization: Professional Engineering
Lines: 22
Approved: bionews-moderator@net.bio.net
Xref: biosci bionet.announce:606 bionet.software:5392 comp.edu:1462 sci.aeronautics:1478 sci.bio:4037 sci.bio.technology:468 sci.chem:5667 sci.edu:1318 sci.electronics:19801 sci.energy:6532

The University of New Mexico College of Engineering will offer a three-day
workshop on Computer Algebra Systems emphasizing Mathematica.  The workshop
will take place August 2-4, 1993.

The course will be taught by three experts in computer algebra systems,
Professors Eric Nuttall and Stanly Steinberg of UNM, and Dr. Michael Wester,
of Cotopaxi.

The course begins with an overview of the various major computer algebra
systems (CASs) and an introduction to what kinds of problems can and
cannot be solved with them.  This will be followed by an in-depth discussion
of the CAS Mathematica with live demonstrations of Mathematica's key functions
and operations,  Practical experience in solving engineering problems will be
provided along with actual student hands-on training and tutorials.

The course is intended for professionals who are required to perform a wide
range of numerical, symbolic, and graphical analyses, and is suitable for both
beginners and advanced users of Mathematica.

For more registration information, contact the Professional Engineering
Development workshop office at (800) 453-3940 or through e-mail; at
pedws@bootes.unm.edu.

From owner-software@net.bio.net Mon Jul 05 23:00:00 1993
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!usenet.ucs.indiana.edu!indyvax.iupui.edu!imhw400
From: imhw400@indyvax.iupui.edu
Newsgroups: bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
Subject: Re: Looking for xmosaic for VMS
Message-ID: <1993Jul6.090643.1363@indyvax.iupui.edu>
Date: 6 Jul 93 14:06:43 GMT
References: <1993Jul5.092319.7229@mcclb0.med.nyu.edu> <1993Jul5.144457.11025@nic.funet.fi> <1993Jul6.091203.21639@nessie.mcc.ac.uk>
Lines: 19
Xref: biosci bionet.software:5391

In article <1993Jul6.091203.21639@nessie.mcc.ac.uk>, mzagsaa@v4.cgu.mcc.ac.uk (Tony Arnold) writes:
[Deletia]
> These look like the files that NCSA distribute. To my understanding, they
> are all Unix flavour implementation. NCSA does not have a VMS port, but
> if someone has one, please let me know as I am keen to run this
> stuff on our
> aging VAXs.

I got a 1.0 port from BCHM2ACLCB.PURDUE.EDU.  I've also heard of one done by
Martin Gelbaum <MGelbaum@lbl.gov>.  The Purdue port needed some minor work but
looks good.  The amount of code added for VMS is truly amazingly small -- the
NCSA team did a really good job of making Xmosaic portable w.r.t. VMS, whether
they knew it or not.

Join the fun over on comp.infosystems.www if you're interested in Xmosaic.
-- 
Mark H. Wood, Lead Systems Programmer    +1 317 274 0749   [@disclaimer@]
Internet:  IMHW400@INDYVAX.IUPUI.EDU     BITNET:  IMHW400@INDYVAX
Celebrate freedom:  read a banned newsgroup.

From owner-software@net.bio.net Tue Jul 06 23:00:00 1993
Path: biosci!uwm.edu!cs.utexas.edu!uunet!pipex!uknet!pavo.csi.cam.ac.uk!mrc-lmb.cam.ac.uk!rs
From: rs@mrc-lmb.cam.ac.uk (Staden R.)
Newsgroups: bionet.molbio.embldatabank,bionet.software
Subject: Re: Use of sequence library indexes
Message-ID: <1993Jul7.135349.4203@infodev.cam.ac.uk>
Date: 7 Jul 93 13:53:49 GMT
References: <1993Jul1.234108.1@molbiol.ox.ac.uk> <1993Jul2.055206.7673@comp.bioz.unibas.ch>
Sender: news@infodev.cam.ac.uk (USENET news)
Organization: MRC Laboratory of Molecular Biology, Cambridge UK
Lines: 39
Xref: biosci bionet.molbio.embldatabank:204 bionet.software:5395
Nntp-Posting-Host: al.mrc-lmb.cam.ac.uk

There have been several articles about the use of indexes for extracting
entries from the sequence libraries and the problems that gcg has when
an accession number occurs in more than one entry.

Mention was made of a package (SRS) that does not have this problem.

Readers may be interested to know of our own method of dealing with
sequence library indexes (and which also does not suffer from the
accession number problem).

We decided to use the indexing system that is included on the EMBL
cdrom, and using it we can extract entries based on accession number
and entry name. In addition we can perform instantaneous author and
text searches (the text indexes include every non-trivial word throughout
an entry - not just the keywords - so we find it very useful).           

So this allows us to use EMBL and SWISSPROT from the cdrom (or copied
to disk for extra speed), but we also wanted to be able to use EMBL updates
and PIR and GenBank. To make this possible we wrote software to
create EMBL cdrom style indexes for all libraries ie we create
entryname, accession number, author and freetext indexes for all
library formats. It is important to realise that we do not change
the libraries, but leave them as distributed. Not having to reformat
or change the libraries obviously saves a great deal of time and
temporary disk space.

An article dexcribing the initial work on this subject was buried
in Staden,R and Dear,S "Indexing the sequence libraries: software
providing a common indexing system for all the standard sequence 
libraries. DNA Sequence 3, 99-105 (1992).

Rodger Staden



-- 
Rodger Staden, Medical Research Council Laboratory Of Molecular Biology,
Hills Road, Cambridge, CB2 2QH, ENGLAND     Telephone: 0223 402389
Internet: rs@UK.AC.Cam.MRC-LMB              Facsimile: 0223 412282

From owner-software@net.bio.net Tue Jul 06 23:00:00 1993
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!howland.reston.ans.net!math.ohio-state.edu!wupost!waikato.ac.nz!canterbury.ac.nz!chmeds.ac.nz!mkennedy
From: mkennedy@chmeds.ac.nz (Martin Kennedy)
Newsgroups: bionet.software
Subject: Re: Gopher Hole for GBASE???
Message-ID: <1993Jul7.132002.273@chmeds.ac.nz>
Date: 7 Jul 93 01:20:02 GMT
References: <9307021851.AA15181@net.bio.net>
Distribution: bionet
Lines: 32

In article <9307021851.AA15181@net.bio.net>, MJA12046%USA.decnet@USAV01.GLAXO.COM ("USA::MJA12046") writes:
> Hi,
>      Does anyone know of a way to access the GBASE (mouse genetic map data)
> through Gopher?
> thanks!
> 
> Mike Agostino
> Glaxo, Inc.             
> mja12046@usav01.glaxo.com

Mike,

Gopher to merlot.welch.jhu.edu, then select:

 -->13 Search databases at Hopkins...
      
	-->8 Mouse databases
        
		 -->1 Encyclopaedia of the mouse genome


I haven't played with it, but it seems to be up and running.

Good luck,

Martin

NNNN   NN  Martin A Kennedy (E-mail = mkennedy@chmeds.ac.nz)  ZZZZZZZ  
NN NN  NN       Cytogenetic and Molecular Oncology Unit          ZZZ
NN  NN NN           Christchurch School of Medicine            ZZZ
NN   NNNN              Christchurch, New Zealand              ZZZZZZZ
		Phone (64-3)364-0880  Fax (64-3)364-750

From owner-software@net.bio.net Tue Jul 06 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!math.ohio-state.edu!caen!batcomputer!munnari.oz.au!sol.deakin.OZ.AU!ausom!klb
From: klb@ausom.oz.au (Kevin Blaze)
Newsgroups: bionet.software
Subject: Wanted - Software advice - Biological classification/identification
Message-ID: <1993Jul7.200347.7244@ausom.oz.au>
Date: 7 Jul 93 20:03:47 GMT
Organization: AUSOM - The Apple Users Society of Melbourne
Lines: 14

I need a program that will help me to produce a biological key (for identificatio
n). Presumably, it will produce a dendrogram. Presumably, I will be able to enter
data that is coded either a) as presence or absence, or b) as numeric.

I would prefer it to run on the Mac.

Please reply to klb@ausom.oz.au

Kevin L. Blaze
VCAH (Burnley)
Burnley Gardens
Swan St
Richmond
AUSTRALIA 3121

From owner-software@net.bio.net Wed Jul 07 23:00:00 1993
Path: biosci!agate!spool.mu.edu!nigel.msen.com!yale.edu!news.yale.edu!news
From: STONE@biomed.med.yale.edu (Lynna Stone-Infeld)
Newsgroups: bionet.software
Subject: HP7475 -> postscript translator
Message-ID: <1993Jul8.201006.1651@news.yale.edu>
Date: 8 Jul 93 20:10:06 GMT
Sender: news@news.yale.edu (USENET News System)
Organization: Yale University
Lines: 26
Nntp-Posting-Host: biomed.med.yale.edu
X-News-Reader: VMS NEWS 1.20




   I seem to remember a Mac application that would convert HP7475 output to
postscript. I have looked on several FTP servers and don't see it. Does anyone
know if such a thing exists and where I could get it. Thanks.

- Lynna
=======================================================================
- Lynna Stone-Infeld, Manager, User Services
               AND    Manager, Molecular Biology Computing Resources
                          Internet:  STONE@BIOMED.MED.YALE.EDU
                                  Bitnet: STONE@YALEMED
Biomedical Computing Unit, Yale University, School of Medicine 
P.O. Box 3333, New Haven, CT, 06510
=======================================================================


=======================================================================
- Lynna Stone-Infeld, Manager, User Services
               AND    Manager, Molecular Biology Computing Resources
                          Internet:  STONE@BIOMED.MED.YALE.EDU
                                  Bitnet: STONE@YALEMED
Biomedical Computing Unit, Yale University, School of Medicine 
P.O. Box 3333, New Haven, CT, 06510
=======================================================================

From owner-software@net.bio.net Wed Jul 07 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!embl-heidelberg.de!rainer-mac.embl-heidelberg.de!user
From: Fuchs@EMBL-Heidelberg.DE (Rainer Fuchs)
Newsgroups: bionet.software
Subject: MacPattern 3.0 available
Message-ID: <Fuchs-080793112340@rainer-mac.embl-heidelberg.de>
Date: 8 Jul 93 10:32:37 GMT
Followup-To: bionet.software
Organization: EMBL Data Library
Lines: 21
Nntp-Posting-Host: rainer-mac.embl-heidelberg.de

The new version 3.0 of the MacPattern sequence analysis program is now
available. MacPattern assists in finding putative functions for new protein
sequences by supporting pattern searches using the PROSITE database, block
searches using the BLOCKS database, and statistical analyses (maximal
segment score analysis). 

Major changes in v3.0 are vastly improved pattern searches (search a 900 aa
protein against all of PROSITE in 6 seconds on a Mac IIcx), a new, faster
approximate block search method, and translations of nucleotide sequences
in three or six reading frames.

MacPattern runs on any Macintosh with at least 750 kb of free RAM and
System version 6.0.5 or greater.

Copies can be obtained by anonymous ftp from ftp.embl-heidelberg.de
(/pub/software/mac/macpattern.hqx) or by email from
Netserv@EMBL-Heidelberg.DE (get mac_software:macpattern.hqx).

Rainer Fuchs
EMBL Data Library
Fuchs@EMBL-Heidelberg.DE

From owner-software@net.bio.net Wed Jul 07 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!gatech!pitt.edu!shannon
From: shannon@belenos.pci.upmc.edu (bill shannon)
Newsgroups: sci.math.num-analysis,bionet.software
Subject: Numerical Recipes in C
Message-ID: <16115@blue.cis.pitt.edu>
Date: 8 Jul 93 16:24:12 GMT
Sender: news+@pitt.edu
Followup-To: sci.math.num-analysis
Organization: Biostatistics Center, Pittsburgh Cancer Institute
Lines: 17
Xref: biosci sci.math.num-analysis:3492 bionet.software:5398
Originator: shannon@belenos


Hi,

	Are the programs from Willaim Press' book 

		"Numerical Recipes in C, 2nd Ed."

available somewhere on the net?  And if so, where?

	I need to do some sorting and would prefer not to type in all
the source code from the book.

	All help is appreciated.  Thanks

Bill Shannon
Pittsburgh Cancer Institute
e-mail:	shannon@atonal.pci.upmc.edu

From owner-software@net.bio.net Wed Jul 07 23:00:00 1993
Path: biosci!uwm.edu!post.its.mcw.edu!not-for-mail
From: halligan@post.its.mcw.edu (Brian Halligan)
Newsgroups: bionet.software
Subject: Re: HP7475 -> postscript translator
Message-ID: <21i7gl$nsb@post.its.mcw.edu>
Date: 8 Jul 93 22:36:05 GMT
References: <1993Jul8.201006.1651@news.yale.edu>
Organization: Medical College of Wisconsin; Milwaukee Wisconsin
Lines: 32
NNTP-Posting-Host: post.its.mcw.edu
X-Newsreader: TIN [version 1.1 PL7]

Lynna Stone-Infeld (STONE@biomed.med.yale.edu) wrote:
: 
: 
: 
:    I seem to remember a Mac application that would convert HP7475 output to
: postscript. I have looked on several FTP servers and don't see it. Does anyone
: know if such a thing exists and where I could get it. Thanks.
: 
: - Lynna
: =======================================================================
: - Lynna Stone-Infeld, Manager, User Services
:                AND    Manager, Molecular Biology Computing Resources
:                           Internet:  STONE@BIOMED.MED.YALE.EDU
:                                   Bitnet: STONE@YALEMED
: Biomedical Computing Unit, Yale University, School of Medicine 
: P.O. Box 3333, New Haven, CT, 06510
: =======================================================================
: 
: 
: =======================================================================
: - Lynna Stone-Infeld, Manager, User Services
:                AND    Manager, Molecular Biology Computing Resources
:                           Internet:  STONE@BIOMED.MED.YALE.EDU
:                                   Bitnet: STONE@YALEMED
: Biomedical Computing Unit, Yale University, School of Medicine 
: P.O. Box 3333, New Haven, CT, 06510
: =======================================================================
-- 
Brian D. Halligan			halligan@post.its.mcw.edu
Assistant Professor			414-257-8413 (voice)
Department of Microbiology		414-257-8427 (FAX)
Medical College of Wisconsin

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!daresbury!buzz.bmc.uu.se!corax.udac.uu.se!sunic!uunet!bloom-beacon.mit.edu!genome.wi.mit.edu!lstein
From: lstein@genome.wi.mit.edu (Lincoln Stein)
Newsgroups: bionet.molbio.gene-linkage,bionet.genome.chromosomes,bionet.software
Subject: ANNOUNCING RELEASE 3 OF WI/MIT CGR MOUSE GENETIC MAP
Keywords: SSLP genetic map linkage genome center mouse mus
Message-ID: <21k03u$i6h@harpo.wi.mit.edu>
Date: 9 Jul 93 14:42:06 GMT
Expires: 1 Aug 1993 00:00:01 GMT
Organization: Whitehead Institute for Biomedical Research
Lines: 65
Xref: biosci bionet.molbio.gene-linkage:195 bionet.genome.chromosomes:53 bionet.software:5405
NNTP-Posting-Host: loco.wi.mit.edu


	    ANNOUNCING THE THIRD RELEASE OF THE WHITEHEAD
	 INSTITUTE/MIT GENOME CENTER GENETIC MAP OF THE MOUSE

Release Three of the Whitehead Institute/MIT Genome Center Genetic Map
of the Mouse is now available.  This map consists of randomly-chosen
simple sequence length polymorphisms (microsatellites) that can be
analyzed using the polymerase chain reaction, as described in
Dietrich, W., et al., Genetics 131:423-447 (1992).

Currently the released map contains 1524 markers.  The markers fall
into 20 linkage groups spanning approximately 1400 cM with an average
spacing of less than 1 cM.

This data can be obtained in two different ways.

1.  Via anonymous ftp to genome.wi.mit.edu.  Log in as "anonymous" and
use your e-mail address as password.  The release can be found in the
directory /distribution/mouse_sslp_release/july93/.  The file "README"
describes the file format and gives other information about the map.

2.  Via internet e-mail using a database e-mail server. Using this
service you can obtain locus and assay names of mapped SSLPs, the
forward and reverse primer sequences, the genotypes of the loci on the
mapping cross, the sizes of the PCR products on selected standard
inbred strains, and other useful information.  The database can be
queried for markers meeting a number of different criteria.  For
example, you can ask for markers by name, by chromosome, or by
position on the map.  You can even request a list of markers that are
polymorphic between two mouse strains.

To obtain copies of the most current query forms, send a message to 
"genome_database@genome.wi.mit.edu" with either a subject line or 
body text of "help". You will receive instructions and a query form by
return mail.  Just fill out the form, send it to
"genome_database@genome.wi.mit.edu", and the answer to your query will
be mailed back automatically.

This project is an ongoing one.  As new markers are added to the map
they will be released on a quarterly basis on approximately the
following schedule:

1 October 1993
1 January 1994
1 April 1994
1 July 1994
&c.

Please address questions and comments to me at the address below.

Lincoln Stein

========================================================================
Lincoln Stein, M.D.,Ph.D.			lstein@genome.wi.mit.edu
MIT Genome Center				(617) 252-1916
Whitehead Institute for Biomedical Research	(617) 252-1902 FAX
9 Cambridge Center
Cambridge, MA 02142
========================================================================

-- 
========================================================================
Lincoln D. Stein
lstein@genome.wi.mit.edu	Whitehead Institute, Cambridge, MA
========================================================================

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!parc!decwrl!pa.dec.com!hydrox.enet.dec.com!mek
From: mek@hydrox.enet.dec.com (Mark Klamerus)
Newsgroups: bionet.software
Subject: Request for Info on Force Field assisted Particle Recognition
Message-ID: <9307091747.AA28403@enet-gw.pa.dec.com>
Date: 9 Jul 93 17:47:39 GMT
Lines: 33
X-Received: by usenet.pa.dec.com; id AA26852; Fri, 9 Jul 93 10:47:40 -0700
X-Received: by enet-gw.pa.dec.com; id AA28403; Fri, 9 Jul 93 10:47:39 -0700
X-Received: from hydrox.enet; by decwrl.enet; Fri, 9 Jul 93 10:47:39 PDT
X-To: bionet.software.usenet
X-Apparently-To: bionet.software.usenet


	Hi,

	I'm currently in the graduate biocomputing program at Wayne
	State Univ in Detroit.  I'm particuarly focusing in on the
	computational aspects of proteins (and associated molecules
	like enzymes, RNA, etc.).  I was looking to do my paper/thesis
	on the information processing aspects of pattern/particle
	recognition of molecules (real or otherwise) assisted by force
	fields (the way protein recognize each other and form mosaics).

	Can anyone point to any works done in this area or provide any
	suggestions/recommendations.  In particular, I've read many
	articles on Brownian Dynamics, but interested to pointers to
	articles on molecular liquids, force fields, diffusion, etc.
	which relate to the above area.  I'm not especially interested
	in the thermodynamics/statistical side of things.  At least, not
	too much on the statistical side.

	I'm especially interested in abstracting the concepts/theories
	away from the physical side of things (for now), but will take
	anything in this area I can get.

	I'm also open for any opinions on whether this seems to be worthy
	of study, any direction to focus this research, discouragement
	(if appropriate), and info on whether this has been done already.

	thanks very much,

	Mark Klamerus
	mek@hydrox.det.dec.com

------- End of Forwarded Message

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!comp.bioz.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Newsgroups: embnet.net-dev,bionet.software
Subject: AXP POSIX
Message-ID: <1993Jul9.113838.29554@comp.bioz.unibas.ch>
Date: 9 Jul 93 11:38:38 GMT
Sender: usenet@comp.bioz.unibas.ch (NEWS transaction account)
Reply-To: doelz@urz.unibas.ch
Organization: EMBnet Switzerland [BASEL]
Lines: 19
Xref: biosci bionet.software:5403
Nntp-Posting-Host: biox.embnet.unibas.ch

I would like to know who would be interested to discuss POSIX on VMS - 
with respect to program usage and maintenance. I need experience 
reports on stability and versatility for biologists, etc. 
Would it make sense to make a software distribution in POSIX also, i.e. 
is it used well enough in biologist's machines to try the effort? 

Thanks 
Reinhard 


-- 
+----------------------------------+-------------------------------------+
|    Dr. Reinhard Doelz            | RFC     doelz@urz.unibas.ch         |
|      Biocomputing                | DECNET  20579::48130::doelz         |
|Biozentrum der Universitaet       | X25     022846211142036::doelz      |
|   Klingelbergstrasse 70          | FAX     x41 61 261- 6760 or 267- 2078     
|     CH 4056 Basel                | TEL     x41 61 267- 2076 or 2247    |   
+------------- bioftp.unibas.ch is the SWISS EMBnet node ----------------+
               -----------------------------------------

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!mcsun!news.funet.fi!ousrvr.oulu.fi!mac36157.oulu.fi!vaisanen
From: vaisanen@lbiok-1.oulu.fi (Timo Visnen)
Newsgroups: bionet.software
Subject: Computer simulated electrophoresis
Message-ID: <vaisanen.2.742219616@lbiok-1.oulu.fi>
Date: 9 Jul 93 12:06:56 GMT
Sender: news@ousrvr.oulu.fi
Organization: Oulun yliopisto
Lines: 8

I would like to find out if there are programs that can simulate DNA 
electrophoresis in agarose/acrylamide gels. If this kind of programs exist, 
are they available from any FTP site ? My PC has MS-DOS/Windows operating 
system. If you have some information about these programs, please mail the 
information to me.

                         Timo Vaisanen
                         timo.vaisanen@oulu.fi

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!NET.BIO.NET!kristoff
From: kristoff@NET.BIO.NET (David Kristofferson)
Newsgroups: bionet.software
Subject: IMPORTANT BIOSCI INFORMATION
Message-ID: <9307090900.AA19054@net.bio.net>
Date: 9 Jul 93 09:00:03 GMT
Sender: kristoff@net.bio.net
Distribution: bionet
Lines: 243


Three important items follow: BIOSCI archive searching by e-mail, the
BIOSCI FAQ, and the BIOSCI User Address Directory form.  If you have
not yet listed yourself in our e-mail address directory, please take a
few minutes to complete and return the form below.  If your address
information has changed since you listed yourself, please send us an
updated form.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net



	  **** SEARCHING BIOSCI ARCHIVES WITH WAISMAIL ****

E-mail users can search the BIOSCI archives by using our waismail
e-mail server.  For instructions send the message

help

to waismail@net.bio.net.  Leave the Subject: line blank.  Other
methods of searching the archives via WAIS and gopher are described in
the BIOSCI FAQ.


       **** BIOSCI FREQUENTLY ASKED QUESTIONS (FAQ) SHEET ****

New users of BIOSCI/bionet may want to read the "Frequently Asked
Questions" or "FAQ" sheet for BIOSCI.  The FAQ provides details on how
to participate in these forums and is available for anonymous FTP from
net.bio.net [134.172.2.69] in pub/BIOSCI/biosci.FAQ.  It may also be
requested by sending e-mail to biosci@net.bio.net (use plain English
for your request).  The FAQ is also posted on the first of each month
to the newsgroup BIONEWS/bionet.announce immediately following the
posting of the BIOSCI information sheet.


	       **** BIOSCI USER ADDRESS DIRECTORY ****

Please take this opportunity to add your name and address information
to the BIOSCI User Address Database if you have not already done so.

Below is the address form that we would like each reader of the
BIOSCI/bionet newsgroups to complete and return if you would like to
be listed in our database.  The database serves as a directory that
enables biologists, who are currently using (or even just reading) the
BIOSCI newsgroups, to look up e-mail addresses and other information
about our users.

The address database is reindexed nightly for WAIS and waismail access
(waismail is our WAIS e-mail server, more below) and will also be
available for access via other gopher sites if they wish to permit it.
The raw unindexed data is available for FTP from net.bio.net and is
atomized sufficiently to allow import into your local RDBMS should you
so desire.

Please carefully follow the instructions for completing the form
below and return it to either of the following two addresses
(whichever is more convenient for you).  Thanks in advance for taking
the time to complete and return the form.

Addresses for returning forms         Location        Network
-----------------------------         --------        -------
biovote@net.bio.net                   U.S.A.          Internet/BITNET
biovote@daresbury.ac.uk               U.K.            JANET


	     MAKING SURE THAT YOUR INFORMATION IS CURRENT

This notice will be mailed bimonthly to each newsgroup.  You should
check our WAIS source or waismail e-mail server from time-to-time to
see if your address information is still up-to-date.  Send the message

help

to waismail@net.bio.net for instructions on using waismail.  Leave the
Subject: line in your message blank.


		  Using Gopher to complete the form
                  ---------------------------------

If you don't want to use a text editor, you can also use Dan
Jacobson's gopher site to fill out the address database form as
follows.  Otherwise skip this section on gopher and proceed to the
instructions for filling out the form below.

> To add yourself to the database just point your
> gopher client at merlot.welch.jhu.edu and select the following:
> 
> -->  15. Searching For Biologists/
> 
>  -->  9.  E-mail Addresses of Biosci-Bionet Users/
> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

> Europeans can point their gopher client at gopher.csc.fi and add their
> information to the database. All entries will be mailed directly to
> Dave for incorporation in a wais source.
> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


	    IMPORTANT INSTRUCTIONS - PLEASE READ CAREFULLY

Please enter all responses after the : on each line, leaving one (1)
blank space after the : (i.e., before the start of your text).

Please do NOT extend your responses past the end of each line (80
characters) or alter any of the field identifiers such as "first name: ". 
Several lines are provided at the end of the form for comments, but,
please adhere to the line length restriction.

On the date: line, please enter the date in the DD-MM-YY format, e.g.,
05-05-93 for 5 May 1993.  This line will tell others when the
information was last updated.  Please be sure to include the 0's for
single digit days or months, e.g., 05-05-93, not 5-5-93.

Note that the "e-mail network: " line below is for specifying, e.g.,
"Internet," "BITNET," "EARN," "JANET," or whatever other network that
your computer may be on.

If you are uncertain about any field, please feel free to leave it
blank, but please DO NOT DELETE the field identifier from the form!

In the first field below, "New information or Update ...", please
enter "N" if this is the first time that you have registered in the
directory or "U" if you are correcting a listing that you sent to us
previously.

The comment: lines may be used for anything that you like but PLEASE
DO NOT DELETE THEM FROM THE FORM OR ALTER THEM.  One suggested use is
to list the names of the newsgroups in which you participate.  Please
use the MAILING LIST name (see below - the latest version of the list
can be requested from biosci@net.bio.net) instead of the USENET name
even if you don't participate by e-mail.  WAIS might get confused by
the periods in the USENET names.  This allows one to retrieve via WAIS
or waismail the list of participants in a particular group.

For example:

comment: ARABIDOPSIS PLANT-BIOLOGY BIONEWS

On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIO-SOFTWARE               bionet.software
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

Listing newsgroups on the comment: line is optional, of course.

Thanks again for your cooperation!



--------------- please cut here and return portion below ---------------

New information or Update to old record (enter N or U): 
date (DD-MM-YY): 
first name: 
middle initial: 
family name: 
job title: 
e-mail address: 
e-mail network: 
phone number: 
FAX number: 
institution: 
address1: 
address2: 
address3: 
city: 
state/province: 
country: 
postal code: 
research interest: 
research interest: 
comment: 
comment: 
comment: 
comment: 
comment: 

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!bcm!cs.utexas.edu!usc!sol.ctr.columbia.edu!usenet.ucs.indiana.edu!indyvax.iupui.edu!imhw400
From: imhw400@indyvax.iupui.edu
Newsgroups: bionet.software,vmsnet.networks.tcp-ip.multinet,vmsnet.sources.d
Subject: Re: Looking for xmosaic for VMS
Message-ID: <1993Jul9.153705.1397@indyvax.iupui.edu>
Date: 9 Jul 93 20:37:05 GMT
References: <1993Jul5.092319.7229@mcclb0.med.nyu.edu> <1993Jul5.144457.11025@nic.funet.fi> <1993Jul6.091203.21639@nessie.mcc.ac.uk> <1993Jul6.090643.1363@indyvax.iupui.edu>
Lines: 9
Xref: biosci bionet.software:5409

In article <1993Jul6.090643.1363@indyvax.iupui.edu>, imhw400@indyvax.iupui.edu writes:
> I got a 1.0 port from BCHM2ACLCB.PURDUE.EDU.  I've also heard of one done by

Oops!  That should be BCHM2.ACLCB.PURDUE.EDU.  (Note the additional period.)
Thanks to David Woodruff at MIT for pointing out the error.  Sorry about that.
-- 
Mark H. Wood, Lead Systems Programmer    +1 317 274 0749   [@disclaimer@]
Internet:  IMHW400@INDYVAX.IUPUI.EDU     BITNET:  IMHW400@INDYVAX
Celebrate freedom:  read a banned newsgroup.

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!JHUHYG.BITNET!NWALKER
From: NWALKER@JHUHYG.BITNET (Nigel Walker)
Newsgroups: bionet.software
Subject: Quantitative scanning eqpmnt
Message-ID: <9307092154.AA21572@net.bio.net>
Date: 9 Jul 93 21:23:44 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 20

Hi all

Ive read recently that several groups have been using Macs,scanners, Photoshop
and Image to do quantitation of Northen blot autoradiograms.

How does this package compare with the PDI Quantity One software (for unix) and
the Biorad quantitation systems that cost 12-15K. Does the type of scanner
significantly affect the quantitation or do the $1-2K scanners at 600dpi do
as good a job?

What software do others out there use for Northern quantitation and how
fast is it? Time is our problem at the moment with single autorads taking sev.
hours to complete analyses that can be done in minutes on other systems.

Thanks in advance

Nigel Walker

Johns Hopkins University
Batimore USA

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!harpo.wi.mit.edu
From: lstein@harpo.wi.mit.edu (Lincoln Stein)
Newsgroups: bionet.announce,bionet.genome.chromosomes,bionet.software,bionet.molbio.gene-linkage
Subject: ANNOUNCING RELEASE 3 OF WI/MIT CGR MOUSE GENETIC MAP
Keywords: SSLP genetic map linkage genome center mouse mus
Message-ID: <21jv8f$hlt@harpo.wi.mit.edu>
Date: 9 Jul 93 14:27:27 GMT
Sender: kristoff@net.bio.net
Followup-To: lstein@genome.wi.mit.edu
Organization: Whitehead Institute for Biomedical Research
Lines: 66
Approved: bionews-moderator@net.bio.net
Xref: biosci bionet.announce:617 bionet.genome.chromosomes:54 bionet.software:5407 bionet.molbio.gene-linkage:196


	    ANNOUNCING THE THIRD RELEASE OF THE WHITEHEAD
	 INSTITUTE/MIT GENOME CENTER GENETIC MAP OF THE MOUSE

Release Three of the Whitehead Institute/MIT Genome Center Genetic Map
of the Mouse is now available.  This map consists of randomly-chosen
simple sequence length polymorphisms (microsatellites) that can be
analyzed using the polymerase chain reaction, as described in
Dietrich, W., et al., Genetics 131:423-447 (1992).

Currently the released map contains 1524 markers.  The markers fall
into 20 linkage groups spanning approximately 1400 cM with an average
spacing of less than 1 cM.

This data can be obtained in two different ways.

1.  Via anonymous ftp to genome.wi.mit.edu.  Log in as "anonymous" and
use your e-mail address as password.  The release can be found in the
directory /distribution/mouse_sslp_release/july93/.  The file "README"
describes the file format and gives other information about the map.

2.  Via internet e-mail using a database e-mail server. Using this
service you can obtain locus and assay names of mapped SSLPs, the
forward and reverse primer sequences, the genotypes of the loci on the
mapping cross, the sizes of the PCR products on selected standard
inbred strains, and other useful information.  The database can be
queried for markers meeting a number of different criteria.  For
example, you can ask for markers by name, by chromosome, or by
position on the map.  You can even request a list of markers that are
polymorphic between two mouse strains.

To obtain copies of the most current query forms, send a message to 
"genome_database@genome.wi.mit.edu" with either a subject line or 
body text of "help". You will receive instructions and a query form by
return mail.  Just fill out the form, send it to
"genome_database@genome.wi.mit.edu", and the answer to your query will
be mailed back automatically.

This project is an ongoing one.  As new markers are added to the map
they will be released on a quarterly basis on approximately the
following schedule:

1 October 1993
1 January 1994
1 April 1994
1 July 1994
&c.

Please address questions and comments to me at the address below.

Lincoln Stein

========================================================================
Lincoln Stein, M.D.,Ph.D.			lstein@genome.wi.mit.edu
MIT Genome Center				(617) 252-1916
Whitehead Institute for Biomedical Research	(617) 252-1902 FAX
9 Cambridge Center
Cambridge, MA 02142
========================================================================


-- 
========================================================================
Lincoln D. Stein
lstein@genome.wi.mit.edu	Whitehead Institute, Cambridge, MA
========================================================================

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!uunet!elroy.jpl.nasa.gov!news.claremont.edu!nntp-server.caltech.edu!seqvax.caltech.edu!mathog
From: mathog@seqvax.caltech.edu (David Mathog)
Newsgroups: bionet.software
Subject: Cheapest color hardcopy for protein structures?
Message-ID: <8JUL199316592422@seqvax.caltech.edu>
Date: 9 Jul 93 00:59:00 GMT
Organization: Division of Biolgy, CALTECH
Lines: 23
NNTP-Posting-Host: seqvax.bio.caltech.edu
News-Software: VAX/VMS VNEWS 1.41

We need color hardcopy for a protein structure class where students will be
generating images on SGI workstations.  We can already get screen dumps to
a slidemaker, but that works out to around $1.00/picture.

We'd like to get the cost below 20 cents per image.

Speed is also a concern - images should print in no more than a minute or
two.

Around 90% of the images don't need shading and consist only of lines and 
points.  It would be a big help if we could at least get these printed 
cheaply.

Are color inkjet printers a good place to start looking?  Anybody have
experience with these in this application? 

Other suggestions?

Thanks,

David Mathog
mathog@seqvax.bio.caltech.edu
Manager, sequence analysis facility, biology division, Caltech

From owner-software@net.bio.net Thu Jul 08 23:00:00 1993
Path: biosci!Corp.Sun.COM!Alexandre.Valais
From: Alexandre.Valais@Corp.Sun.COM (Alexandre Valais)
Newsgroups: bionet.software
Subject: GCG ...
Message-ID: <9307091940.AA09196@frenchy.Corp.Sun.COM>
Date: 9 Jul 93 19:40:31 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 11


Need a contact name , phone and fax number for GCG .

Thanks a lot .

_______________________________________________________________________________
Alexandre V. Valais			phone# : 415-336-0771
Medical & Biotech MSMgr			fax#   : 415-336-0643
E&R Market Dev. Group
TIMDG / Sun Microsystems		email  : Alexandre.Valais@Corp.Sun.COM
_______________________________________________________________________________

From owner-software@net.bio.net Fri Jul 09 23:00:00 1993
Path: biosci!NATURE.BERKELEY.EDU!bosborne
From: bosborne@NATURE.BERKELEY.EDU
Newsgroups: bionet.software
Subject: mapmaker3 for NeXTStep?
Message-ID: <9307100432.AA03184@nature.berkeley.edu.cnr-net>
Date: 10 Jul 93 04:32:33 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 16


To the group,
Has anyone compiled mapmaker3 on a NeXT? And could they
tell me how they did it? According to the documentation
this could be straightforward, but I believe they mean
for those who are educated in these matters. The simplest
attempts like 'cc' -> 'cc -bsd' aren't sufficent. I will
certainly summarize back to the group.

Thank you for your attention to these matters,


   ------------------------------------------------------------
    Brian Osborne		  Plant Gene Expression Center
    bosborne@nature.berkeley.edu  Albany CA USA
   ------------------------------------------------------------

From owner-software@net.bio.net Fri Jul 09 23:00:00 1993
Path: biosci!NET.BIO.NET!web!ceniai.cu!ingen.cu!carmas
From: web!ceniai.cu!ingen.cu!carmas@NET.BIO.NET (Carlos Israel Armas)
Newsgroups: bionet.software
Subject: POPmail and NUPOP source code?
Message-ID: <m0oERur-0001BlC@ingen.cu>
Date: 9 Jul 93 23:31:44 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 14

Hi netters!
anyone knows where to ftp for the source code of POPmail or NUPOP?
both run on IBM PC  MSDOS. I don't have access to archie or ftp.
it's clients for POP services. (RFCs 1081, 1082)
thanks a lot in advance,
warm regards,
carlos
-- 
carlos armas		carmas%ingen@web.apc.org
network manager		automation division
center of genetic engineering & biotechnology
pobox 6162		havana, cuba
voice: 537 218200       fax: 537 218070


From owner-software@net.bio.net Fri Jul 09 23:00:00 1993
Path: biosci!parc!decwrl!ames!agate!usenet.ins.cwru.edu!axa12-slip.DIALIN.CWRU.Edu!ashok
From: ashok@biochemistry.cwru.edu (Ashok Aiyar)
Newsgroups: bionet.software
Subject: Re: POPmail and NUPOP source code?
Message-ID: <ashok.936.0@biochemistry.cwru.edu>
Date: 10 Jul 93 15:45:25 GMT
References: <m0oERur-0001BlC@ingen.cu>
Distribution: bionet
Organization: Department of Biochemistry, Case Western Reserve University
Lines: 19
NNTP-Posting-Host: axa12-slip.dialin.cwru.edu

In article <m0oERur-0001BlC@ingen.cu> web!ceniai.cu!ingen.cu!carmas@NET.BIO.NET (Carlos Israel Armas) writes:

>Hi netters!
>anyone knows where to ftp for the source code of POPmail or NUPOP?
>both run on IBM PC  MSDOS. I don't have access to archie or ftp.
>it's clients for POP services. (RFCs 1081, 1082)

To the best of my knowledge, source code for either is not available.  If 
you are interested in looking at POP2 or POP3 client code, I would recommend 
taking a look at the source for the KA9Q clients.  Off course these are not 
GUI clients ....

Ashok

--
Ashok Aiyar                        Mail: ashok@biochemistry.cwru.edu
Department of Biochemistry                       Tel: (216) 368-3300
CWRU School of Medicine, Cleveland, Ohio         Fax: (216) 368-4544
MIME Enclosures OK

From owner-software@net.bio.net Sat Jul 10 23:00:00 1993
Path: biosci!uwm.edu!wupost!uunet!news.claremont.edu!pomona.claremont.edu!GREG
From: greg@pomona.claremont.edu (Tigger)
Newsgroups: bionet.software,vmsnet.sources.d,vmsnet.mail.pmdf
Subject: Re: Need source-code for BinHex
Message-ID: <0096F57F.221357E4@pomona.claremont.edu>
Date: 11 Jul 93 21:21:28 GMT
References: <1993Jul11.112112.7233@mcclb0.med.nyu.edu>
Sender: news@news.claremont.edu (The News System)
Reply-To: greg@pomona.claremont.edu
Organization: Pomona College
Lines: 10
Xref: biosci bionet.software:5415

In article <1993Jul11.112112.7233@mcclb0.med.nyu.edu>, smith@mcclb0.med.nyu.edu writes:
>
>Does anyone know where I could find a copy of the source for BinHex.

I don't know about source, but there is a document called binhex-40-specs.txt
available via anonymous ftp from the Info-Mac archives at
sumex-aim.stanford.edu (36.44.0.6), in /info-mac/dev/info.  That should
probably tell you everything you need to know to write your own code.

Greg

From owner-software@net.bio.net Sat Jul 10 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!ux1.cso.uiuc.edu!uwm.edu!rutgers!mcclb0.med.nyu.edu!smith
From: smith@mcclb0.med.nyu.edu
Newsgroups: bionet.software,vmsnet.sources.d,vmsnet.mail.pmdf
Subject: Need source-code for BinHex
Message-ID: <1993Jul11.112112.7233@mcclb0.med.nyu.edu>
Date: 11 Jul 93 16:21:12 GMT
Organization: NYU Medical Center, New York, NY 10016, USA
Lines: 15
Xref: biosci bionet.software:5414

Does anyone know where I could find a copy of the source for BinHex.

My goal is to get a version that will run on a VAX (or under UNIX for that
matter). We want it so as to be able to process BinHex stuff from a Mac
without having to play silly file-server games and unBinHex it on a Mac. 
This is to deal with BinHexed mail attachments that come from people with Macs
using Eudora. 

I seem to remember that there is a MS-DOS version somwewhere.  Maybe this 
would be a good place to start, if someone has not already done the job...

+----------------------------------------------------------------------------+
|Ross Smith,  Research Computing Resource, Department of Cell Biology, NYU-MC|
|E-Mail:  SMITH@NYUMED.BITNET (BITNET),   SMITH@MCCLB0.MED.NYU.EDU (Internet)|
+----------------------------------------------------------------------------+

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: CHRIS@wwg3.uovs.ac.za
Newsgroups: bionet.software
Subject: Re: Need source-code for BinHex
Message-ID: <1993Jul12.080738.15629@gserv1.dl.ac.uk>
Date: 12 Jul 93 10:08:11 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Organization: Computer Sience, UOFS, Bfn, RSA
Lines: 33
Original-To: bio-software@uk.ac.daresbury
Priority: normal
X-Mailer: Pegasus Mail v2.3 (R5).
Return-Receipt-To: CHRIS@wwg3.uovs.ac.za


Does anyone know where I could find a copy of the source for BinHex.

My goal is to get a version that will run on a VAX (or under UNIX for that
matter). We want it so as to be able to process BinHex stuff from a Mac
without having to play silly file-server games and unBinHex it on a Mac.
This is to deal with BinHexed mail attachments that come from people with Macs
using Eudora.

I seem to remember that there is a MS-DOS version somwewhere.  Maybe this
would be a good place to start, if someone has not already done the job...

+----------------------------------------------------------------------------+
|Ross Smith,  Research Computing Resource, Department of Cell Biology, NYU-MC|
|E-Mail:  SMITH@NYUMED.BITNET (BITNET),   SMITH@MCCLB0.MED.NYU.EDU (Internet)|
+----------------------------------------------------------------------------+

Dear Ross Smith,

I have found a BinHex program for MS-DOS.  I have searched in vain
for a MS-DOS version of DeBinHex.

Kind regards
Chris


___________________________________________________________________
|Chris Viljoen                   | Dept. of Microbiology &         |
|Internet: chris@wwg3.uovs.ac.za | Biochemistry                    |
|Telephone: (051) 401-2875       | Univ. of the Orange Freestate   |
|Telefax: 27/51/482004           | P.O. Box 339, Bloemfontein, 9300|
|                                | South Africa                    |
-------------------------------------------------------------------

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!ARTHUR.CITI2.FR!CHASSE
From: CHASSE@ARTHUR.CITI2.FR
Newsgroups: bionet.software
Subject: Looking for an aligment sw for PC
Message-ID: <930712120600.2020cc8e@ARTHUR.CITI2.FR>
Date: 12 Jul 93 10:06:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 7


	 I am looking for a DOS or WINDOWS program for IBM-PC which is doing a aligment with two sequences ( a program as KANEHISA on VMS ).

					J.F.CHASSE

					CHASSE@arthur.citi2.fr   


From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!agate!library.ucla.edu!psgrain!ee.und.ac.za!ford.ee.up.ac.za!zeno.up.ac.za!bio1
From: bio1@navi.up.ac.za (Fourie Joubert)
Newsgroups: bionet.software
Subject: NIH Image question
Message-ID: <bio1.270.0@navi.up.ac.za>
Date: 12 Jul 93 12:55:23 GMT
Organization: University of Pretoria
Lines: 16
NNTP-Posting-Host: zeno.up.ac.za

I'm thinking of putting together a Mac system for gel analysis using NIH 
Image. Can NIH Image read TIFF or similar files created on a PC scanner?

If not, is there a relatively cheap card available for connecting a Mac to 
our lab video camera?

Please mail, thanks a lot!!
__________________________________________________________________________

     _/_/_/_/  _/_/_/_/_/  Fourie Joubert           
    _/            _/     Department of Biochemistry
   _/            _/    University of Pretoria
  _/_/_/_/      _/   South Africa
 _/            _/  bio1@navi.up.ac.za
_/      _/_/_/_/                                 Disclaimer: "Fourie who?"
__________________________________________________________________________

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!uwm.edu!math.ohio-state.edu!darwin.sura.net!gatech!willis1.cis.uab.edu!ramermac.nrc.uab.edu!user
From: ramer@nrc-iris.nrc.uab.edu (Kevin W. Ramer)
Newsgroups: bionet.software
Subject: Re: Need source-code for BinHex
Message-ID: <ramer-120793094937@ramermac.nrc.uab.edu>
Date: 12 Jul 93 14:51:50 GMT
References: <1993Jul11.112112.7233@mcclb0.med.nyu.edu> <0096F57F.221357E4@pomona.claremont.edu>
Sender: root@cis.uab.edu (Operator)
Followup-To: bionet.software,vmsnet.sources.d,vmsnet.mail.pmdf
Organization: UAB - Neurobiology Research Center
Lines: 19

In article <0096F57F.221357E4@pomona.claremont.edu>,
greg@pomona.claremont.edu (Tigger) wrote:
> 
> In article <1993Jul11.112112.7233@mcclb0.med.nyu.edu>, smith@mcclb0.med.nyu.edu writes:
> >
> >Does anyone know where I could find a copy of the source for BinHex.
> 
> I don't know about source, but there is a document called binhex-40-specs.txt
> available via anonymous ftp from the Info-Mac archives at
> sumex-aim.stanford.edu (36.44.0.6), in /info-mac/dev/info.  That should
> probably tell you everything you need to know to write your own code.
That being said:
There are various unix utilities located at sumex-aim.stanford.edu.
Among them are xbin, mcvert, macbinary, unsit.  These will convert
various formats for transfer to your mac.


--
Kevin

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!uwm.edu!math.ohio-state.edu!cs.utexas.edu!uunet!nih-csl!pico.nimh.nih.gov!user
From: wayne@helix.nih.gov (Wayne Rasband)
Newsgroups: bionet.software
Subject: Re: NIH Image question
Message-ID: <wayne-120793101053@pico.nimh.nih.gov>
Date: 12 Jul 93 15:26:52 GMT
References: <bio1.270.0@navi.up.ac.za>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Followup-To: bionet.software
Organization: NIH
Lines: 23

In article <bio1.270.0@navi.up.ac.za>, bio1@navi.up.ac.za (Fourie Joubert)
wrote:
> 
> I'm thinking of putting together a Mac system for gel analysis using NIH 
> Image. Can NIH Image read TIFF or similar files created on a PC scanner?

NIH Image can read 8-bit uncompressed TIFF files created on little-endian
DOS/Windows machines. Image 1.50(now in beta) adds the ability to import
16-bit TIFF files.

> If not, is there a relatively cheap card available for connecting a Mac to 
> our lab video camera?

The least expensive frame grabber directly supported by NIH Image is
the Scion LG-3, which has a list price of $895. Scion's phone number is
301-695-7870. The Image 1.50 beta can acquire images from any Mac
frame grabber or scanner that has a Photoshop plug-in.

The current version of NIH Image(1.49), as well as the 1.50 beta, are
available by anonymous FTP from zippy.nimh.nih.gov[128.231.98.32],
in the /pub/image directory.

--wayne

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!uwm.edu!post.its.mcw.edu!pixel.cellbio.mcw.edu!ttrusk
From: ttrusk@its.mcw.edu (Thomas Trusk, PhD)
Newsgroups: bionet.software
Subject: Re: NIH Image question
Message-ID: <ttrusk.17.2C417409@its.mcw.edu>
Date: 12 Jul 93 16:24:10 GMT
References: <bio1.270.0@navi.up.ac.za>
Organization: Medical College of Wisconsin
Lines: 19
NNTP-Posting-Host: pixel.cellbio.mcw.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev Final Beta #7]

In article <bio1.270.0@navi.up.ac.za> bio1@navi.up.ac.za (Fourie Joubert) writes:
>I'm thinking of putting together a Mac system for gel analysis using NIH 
>Image. Can NIH Image read TIFF or similar files created on a PC scanner?

>If not, is there a relatively cheap card available for connecting a Mac to 
>our lab video camera?

We've had NO trouble getting ANY computer image data, no matter what the 
source, into NIH Image. Just know the format!


*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*==**=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*==*
*Thomas Trusk, PhD                   *                                     *
*Dept. of Cellular Biology & Anatomy *  I'm a peripheral visionary.        *
*Medical College of Wisconsin        *  I can see into the future...       *
*Milwaukee, WI  53226                *  Just way off to the side.          *
*MaBellNet: (414) 257-8504           *                                     *
*INTERNET: ttrusk@its.mcw.edu        *                  Steven Wright      *
*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*==**=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*==*

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!UVVM.UVIC.CA!JCOWARD
From: JCOWARD@UVVM.UVIC.CA
Newsgroups: bionet.software
Subject: CALL FOR PAPERS - ITCH'94
Message-ID: <9307121700.AA21979@net.bio.net>
Date: 12 Jul 93 16:58:10 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 76



                        ITCH 1994
         INFORMATION TECHNOLOGY IN COMMUNITY HEALTH

              OCTOBER 30 - NOVEMBER 2, 1994
                  VICTORIA, B.C. CANADA

             A CONFERENCE ADDRESSING INFORMATION
            TECHNOLOGY ISSUES IN COMMUNITY HEALTH

      2nd:          CALL FOR PAPERS

This conference provides a forum for academics, health professionals
and computer system professionals to present and exchange of ideas
and research results in the general area of information technology
for community health. Prospective contributors to the ITCH '94
Conference are encouraged to address topics in the following list.

Technology
*       Community health data networks
*       Health data communication protocols
*       Appropriate technology
*       Telehealth

Policy
*       Community health system assessment
*       Community health system planning
*       Program evaluation
*       Cost/benefit analysis
*       Technology assessment

Applications
*       Community health information systems
*       Community health information resources
*       Diagnostic and clinical expert systems
*       Client and care giver education
*       Community health databases
*       Rehabilitation
*       Software user interfaces
*       User interfaces for the disabled
*       Systems for developing countries

Papers should be limited to 20 minutes in length. Abstracts of 250
words will be accepted up to February 15 1994; authors will be
notified by March 15 1994 and completed papers will be due August
15 1994. Please submit your abstract to:

Dr. Kenneth Thornton, Chairman
ITCH '94 - Scientific Program Committee
School of Health Information Science
University of Victoria
P.O. Box  3050, Victoria B.C.
V8W 3P5

SUBMISSIONS MAY BE SENT BY E-MAIL TO:   KTHORNTO@HSD.UVIC.CA
or by fax to (604) 721-1457

To obtain more information about the conference, please contact:

Dr. Paul Fisher, Chairman - ITCH '94
School of Health Information Science
University of Victoria
P.O. Box  3050, Victoria B.C.
V8W 3P5

INQUIRIES MAY BE SENT BY E-MAIL TO:PFISHER@HSD.UVIC.CA
or by phone at (604) 721-8575 or by fax to (604) 721-1457

Paul Fisher, Ph.D.
School of Health Information Science
The University of Victoria
Box 3050 Victoria B.C., Canada

Phone:  (604) 721-8578
FAX:    (604) 721-1457

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!usc!cs.utexas.edu!uunet!mcsun!sunic!trane.uninett.no!nntp.uio.no!NewsWatcher!user
From: olam@radium.uio.no (Ola Myklebost)
Newsgroups: bionet.software
Subject: Re: NIH Image question
Message-ID: <olam-120793172647@129.240.38.55>
Date: 12 Jul 93 15:22:59 GMT
References: <bio1.270.0@navi.up.ac.za>
Followup-To: bionet.software
Organization: Inst for Cancer Research, Oslo
Lines: 16
NNTP-Posting-Host: pcdnr05.uio.no

In article <bio1.270.0@navi.up.ac.za>, bio1@navi.up.ac.za (Fourie Joubert)
wrote:
> 
> I'm thinking of putting together a Mac system for gel analysis using NIH 
> Image. Can NIH Image read TIFF or similar files created on a PC scanner?
> 

Yes, you can import the files if you know their header size, length and
width.

Ola Myklebost             Email  ola.myklebost@dnr.uio.no
Dept of Tumor Biology
Inst for Cancer Research
The Norwegian Radium Hospital
N-0310 OSLO, Norway
Tel +47-22-50-60-50, xtn 9830, Fax +47-22-52-24-21

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!uwm.edu!ux1.cso.uiuc.edu!howland.reston.ans.net!usenet.ins.cwru.edu!axa12-slip.cwru.edu!ashok
From: ashok@biochemistry.cwru.edu (Ashok Aiyar)
Newsgroups: bionet.software
Subject: Where to find Binhex/HexBin for DOS (was Re: Need source-code for BinHex)
Message-ID: <ashok.943.2C41EBF5@biochemistry.cwru.edu>
Date: 13 Jul 93 01:55:32 GMT
References: <1993Jul12.080738.15629@gserv1.dl.ac.uk>
Distribution: bionet
Organization: Department of Biochemistry, Case Western Reserve University
Lines: 35
NNTP-Posting-Host: axa12-slip.dialin.cwru.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev Final Beta #7]

In article <1993Jul12.080738.15629@gserv1.dl.ac.uk> CHRIS@wwg3.uovs.ac.za writes:

>Newsgroups: bionet.software
>Does anyone know where I could find a copy of the source for BinHex.

>My goal is to get a version that will run on a VAX (or under UNIX for that
>matter). We want it so as to be able to process BinHex stuff from a Mac
>without having to play silly file-server games and unBinHex it on a Mac.
>This is to deal with BinHexed mail attachments that come from people with Macs
>using Eudora.

>I seem to remember that there is a MS-DOS version somwewhere.  Maybe this
>would be a good place to start, if someone has not already done the job...

>+----------------------------------------------------------------------------+
>|Ross Smith,  Research Computing Resource, Department of Cell Biology, NYU-MC|
>|E-Mail:  SMITH@NYUMED.BITNET (BITNET),   SMITH@MCCLB0.MED.NYU.EDU (Internet)|
>+----------------------------------------------------------------------------+

>Dear Ross Smith,

>I have found a BinHex program for MS-DOS.  I have searched in vain
>for a MS-DOS version of DeBinHex.


Check boombox.micro.umn.edu in /pub/pc/binhex .... works both ways.

I also archive a copy at biochemistry.bioc.cwru.edu in /pub/dos

Ashok
--
Ashok Aiyar                        Mail: ashok@biochemistry.cwru.edu
Department of Biochemistry                       Tel: (216) 368-3300
CWRU School of Medicine, Cleveland, Ohio         Fax: (216) 368-4544
MIME Enclosures OK

From owner-software@net.bio.net Sun Jul 11 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!ux1.cso.uiuc.edu!usenet.ucs.indiana.edu!cricket.bio.indiana.edu!user
From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: Re: NIH Image question
Message-ID: <gilbertd-120793093057@cricket.bio.indiana.edu>
Date: 12 Jul 93 14:37:29 GMT
References: <bio1.270.0@navi.up.ac.za>
Sender: news@usenet.ucs.indiana.edu (USENET News System)
Followup-To: bionet.software
Organization: Biology - Indiana University
Lines: 23
Nntp-Posting-Host: cricket.bio.indiana.edu

In article <bio1.270.0@navi.up.ac.za>, bio1@navi.up.ac.za (Fourie Joubert)
wrote:
> 
> I'm thinking of putting together a Mac system for gel analysis using NIH 
> Image. Can NIH Image read TIFF or similar files created on a PC scanner?

Yes.  Many other common Mac graphics applications can read TIFF also,
including Canvas and Photoshop.


> If not, is there a relatively cheap card available for connecting a Mac to 
> our lab video camera?

Video Spigot is such a card that is inexpensive ($400 for nubus mac, other
models for LC and SI) and links to many kinds of video input -- VCR,
camcorder, TV.  I haven't used one.  I'm looking at the blurb for it in
MacWarehouse mail order catalog.  Phones: 800.622.6222,  Fax: 203.855.1386,
paper mail: MacWareHouse, 47 Water St., Norwalk, CT 06854.    Other Mac
mail-order companies will also sell this.

_________________
Don Gilbert, Biocomputing Office, Biology, Indiana Univ., Bloomington, IN
47405

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!agate!howland.reston.ans.net!math.ohio-state.edu!cs.utexas.edu!uunet!news!demon!genesys.demon.co.uk!Duncan
From: Duncan@genesys.demon.co.uk ("Dr. Duncan Clark")
Newsgroups: bionet.software
Subject: DNA Gel Image capture
Message-ID: <742503147snz@genesys.demon.co.uk>
Date: 12 Jul 93 18:52:27 GMT
Sender: usenet@demon.co.uk
Reply-To: Duncan@genesys.demon.co.uk
Organization: GeneSys Ltd.
Lines: 20
X-Newsreader: Simple NEWS 1.90 (ka9q DIS 1.21)

Hi Netters,

In the most recent Biotechniques, June pp902-905, an inexpensive image capture
system was described complete with equipment sources/cat. no.'s and prices.
The authors gave a price for a Sony UP860 thermal printer as $1000. Here in the
UK that will equate to 1000+ UK pounds regardless of exchange rates etc. I 
asked a friend in the US to check the price and then buy one for me and ship it
over etc. The best price he has been quoted is $1550. Anyone know of a better
source/price. Failing that has anyone a FAX or Email address for the authors,
Stephan Winans or Michael Rooks at Section of Microbiology, National 
Nanofabrication Facility, Cornell University, Ithaca, NY.

Many thanks.

Duncan Clark
-- 
-----------------------------------------------------------------------------
 Duncan Clark                       | Internet:   duncan@genesys@demon.co.uk
 GeneSys Ltd.                       | Compuserve: 100015.1406@compuserve.com
-----------------------------------------------------------------------------

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!uwm.edu!cs.utexas.edu!swrinde!gatech!usenet.ins.cwru.edu!axa12-slip.cwru.edu!ashok
From: ashok@biochemistry.cwru.edu (Ashok Aiyar)
Newsgroups: bionet.software
Subject: Restriction enzyme database in DBF format ....
Message-ID: <ashok.946.2C423A2F@biochemistry.cwru.edu>
Date: 13 Jul 93 07:29:17 GMT
Organization: Department of Biochemistry, Case Western Reserve University
Lines: 11
NNTP-Posting-Host: axa12-slip.dialin.cwru.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev Final Beta #7]


If someone can provide me with the REBASE database in DBF format, I would 
*greatly* appreciate it!

Thanks,
Ashok
--
Ashok Aiyar                        Mail: ashok@biochemistry.cwru.edu
Department of Biochemistry                       Tel: (216) 368-3300
CWRU School of Medicine, Cleveland, Ohio         Fax: (216) 368-4544
MIME Enclosures OK

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!CSC.FI!Rob.Harper
From: Rob.Harper@CSC.FI (Rob Harper)
Newsgroups: bionet.software
Subject: Prospero...
Message-ID: <199307130834.AA07782@csc.fi>
Date: 13 Jul 93 08:34:28 GMT
Sender: daemon@net.bio.net
Lines: 121


>Path: funic!news.funet.fi!sunic!pipex!bnr.co.uk!bnrgate!nott!torn!utnut!cs.utexas.edu!usc!news.isi.edu!venera.isi.edu!swa
>From: swa@ISI.EDU (Steven Seger Augart)
>Newsgroups: comp.infosystems.www
>Subject: Prospero Alpha 5.2 available; relevant to WWW folks
>Date: 7 Jul 93 02:04:36
>Organization: USC-ISI
>Lines: 109
>Distribution: comp
>Message-ID: <SWA.93Jul7020436@zephyr.ISI.EDU>
>NNTP-Posting-Host: zephyr.isi.edu

We posted the following announcement today to comp.infosystems.gopher.
I am posting it here to let you all know that we are working on a
similar integration of WWW and Prospero.

An Alpha release of version 5.2 of the Prospero file system is now
available by anonymous FTP from PROSPERO.ISI.EDU in the file
pub/prospero/prospero-alpha.5.2.tar.Z.  It can also be obtained
through Prospero itself from /releases/prospero/prospero-alpha.5.2.tar.Z.  
The name prospero.tar.Z in those directories still points to the stable
Beta 5.1 release; this has been done for the sake of the archie server
maintainers and other information providers who depend upon Prospero. 

Some important changes since the last Prospero release should be of
interest to the readers of comp.infosystems.gopher:

(a) A menu-based browser client, similar to the Gopher client
(b) A gateway server which makes all of Gopherspace available through 
    Prospero queries. 
(c) A menu-based browser API interface library to Prospero, which allows
    one to easily write new browsers that use Prospero to make their underlying
    calls.

The menu-based browser supports all of the basic Gopher types:
searches, text files, data files, and portals (what Gopher calls
telnet sessions).  It does not yet support sophisticated display of
binary image files, reading Postscript or MIME documents, playing
sounds, or automatic decoding of uuencoded, compressed, or tarred
files.  These enhancements will be added shortly; the protocol
definitions for them have already been made.

We support authenticated remote modifications to menus, though not
presently from within the browser itself.  For now you will have to
learn how to use a few Prospero commands to add new menus or items and
set descriptions.  We plan to eventually support remote update within
the browser itself.

Prospero, and thus menus available to the menu browser (as a Prospero
client), supports fine grained access control based on client
identity.  Authentication is provided using 4 alternative
authentication mechanisms, depending on your specific needs: (a)
Kerberos (version 5); (b) per user passwords; (c) trusted port and
trusted host assertion (like the Berkeley R commands); and (d) a check
of the host from which a request originated and the asserted user
identity of the client.

Prospero provides full access control list mechanisms for those who
wish to put fine-grained permissions on particular objects or
directories.  For instance, one can easily set some directories so
that anybody at your company or university can read data in them, only
a particular group of people can insert data into them, and only the
system administrator or the author of a particular piece of
information is allowed to modify and delete it.  Of course, anyone who
does not need these security mechanisms can export data using the
default permissions defined on a per server basis.

An elegant new Prospero feature we're rather proud of is the search
interface.  We support a variety of search methods, including direct
queries to Prospero-speaking database servers, such as Archie servers
and all Gopher servers via a Prospero-Gopher gateway.  The search
servers are self defining, exporting attributes that tell the client
what to prompt for, help messages to display if requested by the user,
and how to package the search when it is sent to the server.

Client implementors need not worry about the generality of this
mechanism since they can make perfectly functional clients that use
only a small subset of the available data.  The menu browser has a
subset of this search interface built into it.

The philosophy behind this work, or why we are doing this:

One of Gopher's greatest strengths is its clear, straightforward user
interface.  However, the gopher protocol itself has a number of
limitations which keep it from being suitable as a universal Internet
information infrastructure, such as the fact that all updates to data
must be made through means outside the protocol (i.e., editing files
on the server) and its lack of security mechanism.

Most current Internet information services, such as Gopher, World Wide
Web, and WAIS, have their own specialized clients, servers, and
network protocols.  This makes it difficult for these services to
interoperate smoothly.  People attempt to address these issues with
inefficient ad-hoc gateways, such as the Gopher servers that make
Archie queries on behalf of Gopher clients, or even our own
Prospero-Gopher gateway.  These are not very good solutions. 

Prospero provides a framework for integrating information from diverse
sources.  Client writers can work on interesting clients, and service
providers can publish their data, without needing to work on issues of
little interest to them.  We explore these ideas in greater depth in
the paper 'Prospero: A Base for Building Information Infrastructure',
to be presented at the INET '93 conference in August, and available
via anonymous FTP from PROSPERO.ISI.EDU as
/pub/papers/prospero/prospero-bii.ps.Z.

We encourage others to build clients that make their queries through
Prospero and to publish their data through Prospero.  We provide an
application library (much better documented in this release than in
previous ones) and a simple application interface designed
specifically for the authors of read-only menu browsers.  It is also
not difficult to publish your data through Prospero, and we are eager
to work with those who wish to do so.

-- Steven Seger Augart
   Research Staff, USC Information Sciences Institute

-- B. Clifford Neuman
   Scientist, USC Information Sciences Institute

email: info-prospero@isi.edu

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: daj@nhm.ic.ac.uk ((David Johnston) daj)
Newsgroups: bionet.software
Subject: Re: POPmail and NUPOP source code?
Message-ID: <1993Jul13.083026.2029@gserv1.dl.ac.uk>
Date: 13 Jul 93 08:10:17 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 28
Original-To: bio-software@uk.ac.daresbury
X-Popmail-Charset: British
Original-Cc: daj@uk.ac.ic.nhm

On 9 Jul 93 23:31:44 GMT,
  Carlos Israel Armas writes:

>Hi netters!
>anyone knows where to ftp for the source code of POPmail or NUPOP?
>both run on IBM PC  MSDOS. I don't have access to archie or ftp.
>it's clients for POP services. (RFCs 1081, 1082)
>thanks a lot in advance,
>warm regards,
>carlos
>-- 
>carlos armas  carmas%ingen@web.apc.org
>network manager  automation division
>center of genetic engineering & biotechnology
>pobox 6162  havana, cuba
>voice: 537 218200       fax: 537 218070

For POPMAIL, try to Email:

popmail@boombox.micro.umn.edu

or write to:

POPmail project
University of Minisota
Room 125 Shepherd Labs
Minneapolis, MN55455
USA

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Newsgroups: bionet.software
Subject: SLIDES/POSTER DRAWING SOFTWARE
Message-ID: <1993Jul13.112631.5240@gserv1.dl.ac.uk>
Date: 13 Jul 93 12:14:00 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 34
Original-To: BIO-SOFTWARE@UK.AC.DARESBURY

From:	CBS%UK.AC.DARESBURY.DLGM::PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK::GRGGTA 13-JUL-1993 11:11:41.42
To:	grggta
CC:	
Subj:	Slides/poster drawing software

Via: UK.AC.DARESBURY.DLGM; Tue, 13 Jul 93  11:11 GMT
Received: by gserv1 (4.1/DL-V2.3)
	id AA03617 ( for dl_sun_server); Tue, 13 Jul 93 10:42:25 BST
Resent-From: <server-daemon@uk.ac.daresbury>
Date: Tue, 13 Jul 1993 09:19:00 GMT
Resent-Date: Tue, 13 Jul 93 10:42:24 UT
To: "bionet.molbio.methds-reagnts mail newsgroup" <bionet-news@uk.ac.daresbury>
Message-Id: <93713104224.MIN-LBBAa03049.bionet-news@uk.ac.daresbury>
Resent-Message-Id: <1993Jul13.085252.2724@gserv1.dl.ac.uk>
From: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Reply-To: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Sender: "bionet.molbio.methds-reagnts mail newsgroup" <bionet-news@uk.ac.daresbury>
Subject: Slides/poster drawing software
X-Article-Number: bionet.molbio.methds-reagnts Msg # 4575
Comments: List problems/queries to <biosci@daresbury.ac.uk>
Comments: To mail both the group and netnews send to (methods@daresbury.ac.uk)

Dear All,
We are about to update our ancient 'GEM' graphics drawing software (circa
1987) for something better. We use this software for molecular biology-
oriented slides, posters, thesis illustrations etc. It includes graph
presentation and drawing applications. I have arrived at three alternatives
 Coreldraw v3 or v4 at 3x the price, harvard graphics or Micrographix Graphics
Works. Our reqiurements are that it should be easy to use and offer as much
control over the image as possible, without requiring 'professional graphics
designer levels of complexity. Our budget extends to 300 sterling and 40MB
(plus DOS v6 file compression ie approx 70MB in total?
Any suggestions or comments?
Graham Atherton

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Newsgroups: bionet.software
Subject: slides/poster drawing software
Message-ID: <1993Jul13.121109.6612@gserv1.dl.ac.uk>
Date: 13 Jul 93 13:11:00 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 34
Original-To: BIO-SOFTWARE@UK.AC.DARESBURY

From:	CBS%UK.AC.DARESBURY.DLGM::PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK::GRGGTA 13-JUL-1993 11:11:41.42
To:	grggta
CC:	
Subj:	Slides/poster drawing software

Via: UK.AC.DARESBURY.DLGM; Tue, 13 Jul 93  11:11 GMT
Received: by gserv1 (4.1/DL-V2.3)
	id AA03617 ( for dl_sun_server); Tue, 13 Jul 93 10:42:25 BST
Resent-From: <server-daemon@uk.ac.daresbury>
Date: Tue, 13 Jul 1993 09:19:00 GMT
Resent-Date: Tue, 13 Jul 93 10:42:24 UT
To: "bionet.molbio.methds-reagnts mail newsgroup" <bionet-news@uk.ac.daresbury>
Message-Id: <93713104224.MIN-LBBAa03049.bionet-news@uk.ac.daresbury>
Resent-Message-Id: <1993Jul13.085252.2724@gserv1.dl.ac.uk>
From: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Reply-To: GRGGTA@PATERSON.CHRISTIE-HOSPITAL.MANCHESTER.AC.UK
Sender: "bionet.molbio.methds-reagnts mail newsgroup" <bionet-news@uk.ac.daresbury>
Subject: Slides/poster drawing software
X-Article-Number: bionet.molbio.methds-reagnts Msg # 4575
Comments: List problems/queries to <biosci@daresbury.ac.uk>
Comments: To mail both the group and netnews send to (methods@daresbury.ac.uk)

Dear All,
We are about to update our ancient 'GEM' graphics drawing software (circa
1987) for something better. We use this software for molecular biology-
oriented slides, posters, thesis illustrations etc. It includes graph
presentation and drawing applications. I have arrived at three alternatives
 Coreldraw v3 or v4 at 3x the price, harvard graphics or Micrographix Graphics
Works. Our reqiurements are that it should be easy to use and offer as much
control over the image as possible, without requiring 'professional graphics
designer levels of complexity. Our budget extends to 300 sterling and 40MB
(plus DOS v6 file compression ie approx 70MB in total?
Any suggestions or comments?
Graham Atherton

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!uwm.edu!cs.utexas.edu!uunet!mcsun!dkuug!uts!biobase!pamaga
From: pamaga@biobase.aau.dk (Paulo Magalhaes)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: AutoR software - new thoughts
Message-ID: <CA3IGD.I01@biobase.aau.dk>
Date: 13 Jul 93 09:02:36 GMT
Organization: The Danish BioBase
Lines: 25
Xref: biosci bionet.molbio.methds-reagnts:6433 bionet.software:5431

A while back I posted a request for "quantification/analysis" of scanned
images of autoradiograms. Thanks for the contributions. Here's a brief
review and some more questions :)

* Image Master, from Pharmacia - it sounds pretty good, but the price is
  ridiculously high...

* PhotoShop for Windows - does this program do exactly the same thing as
  the Mac version? Who commercializes it?

* QuantiScan, from BioSoft - does this program do the same as Image 1.44
  (for the Mac)? Does anyone have any experience with it? It seems as if
  it is a good alternative, but we'd like to know a little more about it
  before we take the plunge. Price, anyone?

* AND AGAIN: we're still looking for a PC program that provides the same
  features as Image 1.44 - amongst other things, we need to quantify and
  print autoRs... Your suggestions will be much appreciated.


That's all for the time being :)

All the best from Copenhagen,

Paulo

From owner-software@net.bio.net Mon Jul 12 23:00:00 1993
Path: biosci!daresbury!daresbury!news
From: Rob.Harper@csc.fi (Rob Harper)
Newsgroups: bionet.software
Subject: Lynx 2.0.10
Message-ID: <1993Jul13.083541.2195@gserv1.dl.ac.uk>
Date: 13 Jul 93 08:36:41 GMT
Sender: harper@fi.csc
Distribution: bionet
Lines: 103
Original-To: bio-soft@uk.ac.daresbury


>Path: funic!vttux1!news.funet.fi!sunic!uunet!news.cnri.reston.va.us!newsserver.jvnc.net!howland.reston.ans.net!math.ohio-state.edu!caen!kuhub.cc.ukans.edu!stat1.cc.ukans.edu!local
>Newsgroups: comp.infosystems.www
>Subject: Lynx 2.0.10 Now Available
>Message-ID: <1993Jul12.181600.51671@kuhub.cc.ukans.edu>
>From: local@stat1.cc.ukans.edu (Lou Montulli)
>Date: 12 Jul 93 18:15:59 CST
>Keywords: Hypertext, browser, Lynx, Version 2.0.10
>Summary: Lynx 2.0.10, a WWW browser, is now available.
>Nntp-Posting-Host: stat1.cc.ukans.edu
>X-Newsreader: TIN [version 1.1 PL9]
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Lynx Ver. 2.0.10 is now available for anonymous ftp from
 FTP2.cc.ukans.edu    as   /pub/lynx/lynx2-0-10.tar.Z

( ftp://ftp2.cc.ukans.edu/pub/lynx/lynx2-0-10.tar.Z )

 *NOTE: This is a new ftp site.
	The old ftp site (acs220) is no longer valid.
	Ftp2.cc.ukans.edu will be the new PERMANENT ftp
	site!  Acs220 will carry a README file explaining
	the new site information for a period of at least
	two to three weeks.

Lynx is a distributed hypertext browser with full World Wide Web
capibilities.  For an explanation of features and a demo, telnet
to "kufacts.cc.ukans.edu" and login as "www".

This release of Lynx has been compiled by me on the following platforms:

 o  IBM (AIX 3.2)
 o  DEC (Ultrix, VMS)
 o  Sun 3 and 4
 o  NeXT (Mine is an older version of NeXTStep, but it should work 
         with newer ones too.)

Binaries for the following platforms are available:

 o  IBM (AIX 3.2, will work with 3.1 as well)
 o  Ultrix
 o  Sun 4
 o  VMS (for multinet)

A new listserv list has been created for the distribution of
Lynx related information and updates.
  o  Lynx-Dev@ukanaix.cc.ukans.edu
 
Send a subscribe request to listserv@ukanaix.cc.ukans.edu to
be added to the list.  All new releases will be anounced on this
list.

The following new features have been added:
  o  IMG tags are recognized and the word [IMAGE] appears in its place. 
        (not in VMS)
  o  "mailto:" URL's are now supported.
  o  Document owners can now be defined using the "link" tag.
	<link rev=made href="mailto:montulli@ukanaix.cc.ukans.edu">
	will define me as the creator of the document.  When the 
	comment feature, the 'C' command in Lynx, is used, Lynx will 
	use the "href" value as the destination of the comment.   (not in VMS)
  o  Now uses the 2.9 version of the WWW Common Code Library. (not in VMS)
  o  Uses the full HTTP/1.0 protocol.
  o  The environment variable WWW_HOME is now recognized. 
  o  Updated search routines.
  o  WAIS support. (not in VMS, except gateway functions)
  o  Optional Emacs-style key definitions.
  o  Gopher Directory format has been changed to show verbose information
        by default, and the screen format has changed.
  o  'V' is now used to "View" the bookmark file.
  o  'G' is now used to "Go" to a random user specified URL.
 