From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!rc1!ub4b!mcsun!Germany.EU.net!sunmbx.netmbx.de!mailgzrz.TU-Berlin.DE!news.dfn.de!immunbio.mpg.de!immunbio.mpg.de!news
From: GARTMANN@IMMUNBIO.MPG.DE (Christoph Gartmann)
Newsgroups: bionet.software
Subject: Re: PIR/GCG
Message-ID: <1993Nov1.165737.54@immunbio.mpg.de>
Date: 1 Nov 93 17:57:37 GMT
References: <1993Oct30.184049.4664@gserv1.dl.ac.uk>
Organization: Max-Planck-Institut fuer Immunbiologie
Lines: 40
Nntp-Posting-Host: mpi1.immunbio.mpg.de
X-News-Reader: VMS NEWS 1.24In-Reply-To: risler%FRCGM51.earn@uk.ac.earn-relay's message of Sat, 30 Oct 1993 23:40:27 GMTLines: 40

In <1993Oct30.184049.4664@gserv1.dl.ac.uk> risler%FRCGM51.earn@uk.ac.earn-relay writes:

> ...
> Well, finally it worked. The .REF and .SEQ files seem to be OK.

Thanks for the hint!

> Now, if I run PIRTOGCG or DBINDEX, I get the following message for *ALL* the
> sequences:
>  
> * no accession number for sequence XXXX *
>  
> Anyway the programs go on, I get the usual .NAMES, .OFFSET, etc...files
> whose size seem reasonable.
>  
> *BUT* I can't FETCH any sequence. If I try to fetch CCHU from PIR1, for
> example, I get  * no files in PIR1:CCHU *  .....
>  
> NOTE 1: I am lazy and I always wait for a certain time before installing the
> minor releases, waiting for other people to find the new bugs ... :-)
> Hence I'm still under GCG #7.0  Is this the reason?
>  
> NOTE 2: The files are NOT in CODATA format. They just look like the good
> old PIR files. However, the accession number is hidden in a line such as:
> c;Accession: xxxxxx
>  

Our .REF-files look like yours and we have no trouble reindexing them. Perhaps
why we have GCG V7.3?

Regards
    Christoph

+----------------------------------------------------------------------------+
| Christoph Gartmann            Phone   : +49-761-5108-465   Fax: -221       |
| Max-Planck-Institut fuer      PSI     : PSI%(0262)45050160374::GARTMANN    |
| Immunbiologie                 Internet: gartmann@immunbio.mpg.de           |
| Postach 1169                                                               |
| D-79011  Freiburg, FRG                                                     |
+------------- Do you know MENUE, the user environment for VMS? -------------+

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!rice
From: rice@embl-heidelberg.de (Peter Rice)
Newsgroups: bionet.software
Subject: Re: PIR/GCG
Message-ID: <1993Nov1.201235.125613@embl-heidelberg.de>
Date: 1 Nov 93 19:12:35 GMT
References: <1993Oct30.184049.4664@gserv1.dl.ac.uk>
Distribution: bionet
Organization: EMBL, European Molecular Biology Laboratory
Lines: 44

In article <1993Oct30.184049.4664@gserv1.dl.ac.uk>, risler%FRCGM51.earn@uk.ac.earn-relay writes:
> Up to now I received the PIR database from MIPS on a magtape. Like many many
> others, I had troubles with the GCG files provided on the tape, which were
> fixed by re-running DBINDEX.
>  
> Now I receive PIR on their CD-ROM. Since I want to use GCG, I have to copy
> the files onto my VAX/VMS. *NOTE* this was a pain in the neck, a CD_MOUNT
> followed by a COPY doesn't work because the resulting file are "undefined".
> The CD_ACCESS program from P. Stockwell, available from the EMBL server,
> doesn't work either on these CD-ROMs (it's the only case I know of).
>  
> You MUST mount the CD-ROM with the following command:
>  
> CD_MOUNT/media=cdrom/UNDEFINED=(STREAM_LF:512)
>  
> It was rather hard to be aware of the UNDEFINED switch ... this may be
> useful to other people...
>  
> Well, finally it worked. The .REF and .SEQ files seem to be OK. Now, if I
> run PIRTOGCG or DBINDEX, I get the following message for *ALL* the
> sequences:
>  
> * no accession number for sequence XXXX *

A wild guess, but perhaps you still have stray characters in the files,
probably carriage returns or line feeds, from not having exactly the right
/undefined definition (which should define the record type to VMS as
the CD-ROM is lacking the necessary information). Try looking at the
REF files with DUMP /BLOCK=END=5 and see what characters appear. You then
have to change the /undefined qualifier on the mount until they look OK.

I have seen similar problems with other CD-ROM copies, but don't have the PIR
one around to check the exact command you need.

It's not their fault - most CD-ROMS suffer from the problem. PIR should
be able to tell you the correct syntax.

 -----------------------------------------------------------------------------
 Peter Rice, EMBL                             | Post: Computer Group
                                              |       European Molecular
 Internet:    Peter.Rice@EMBL-Heidelberg.DE   |            Biology Laboratory
                                              |       Postfach 10-2209
 Phone:   +49-6221-387247                     |       69012 Heidelberg
 Fax:     +49-6221-387306                     |       Germany

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!vixen.cso.uiuc.edu!moe.ksu.ksu.edu!osuunx.ucc.okstate.edu!constellation!aardvark.ucs.uoknor.edu!aardvark.ucs.uoknor.edu!broe
From: broe@aardvark.ucs.uoknor.edu (Bruce Roe)
Newsgroups: bionet.software
Subject: Re: Trace Editors for Macs
Message-ID: <1NOV199308565526@aardvark.ucs.uoknor.edu>
Date: 1 Nov 93 13:56:00 GMT
References: <9310292144.AA27674@farber.harvard.edu>
Distribution: bionet
Organization: University of Oklahoma - University Computing Services
Lines: 107
Nntp-Posting-Host: loopback.uoknor.edu
News-Software: VAX/VMS VNEWS 1.41

In article <9310292144.AA27674@farber.harvard.edu>, morrison@FARBER.HARVARD.EDU (Paul Morrison) writes...
>Harry Mangalam, VCO/Micro+Mol Genetics, Irvine Hall, Coll of Med, UC
>replied to kinneya@esvax.dnet.dupont.com:
> 
>>In article <9310251805.AA10757@esds01.es.dupont.com>,
>>kinneya@esvax.dnet.dupont.com wrote:
>>> 
>>> >I'm looking for Macintosh-based software to help us edit ABI-format
>>> >sequence files.  I would like something like the unix-based TED, which
>>> >prints the ABI-called sequence beneath the DNA migration absorption
>>> >curves and allows you to make adjustments.
>>> 
>>> The "EDITSEQ" sequence editor software for the Mac from DNAStar (which is
>>> also part of their Lasergene package) will do this.
>>> 
>>> Their phone number is (608)258-7420
>>
>>   So will Sequencher, from Gene Codes (and is very expensive if all you're
>>looking for is an editor), but is a complete, powerful, and very easy to
>>use fragment assembly program.  Their phone number is: 313 769 7249; ~$1200
>>w/ hardware lock, site/multiple copy discounts. 
>>   IMHO, Sequencher is the much better of the two for editing and fragment
>>assembly, but it is not a 'full-featured' Sequence analysis pkg ie no
>>protein analysis, not a lot of DNA analysis, which Lasergene does offer.
>>
>>
>>Std Disclaimers..
>>Harry
>>
> 
>Yes indeed there is more than one contig builder out there and I agree
>completely with Harry that Sequencher is the most powerful. One thing that
>caught my attention in the original post was the wording "allows you to
>make adjustments". Now if that is meant to mean make adjustments to the
>called sequence by comparing to other sequences then yes, the programs
>mentioned do this. If it means make adjustments to the raw data data signal
>that comes out of a 373A so that one might be able to tweak paramaters so
>that more sequence is called, I don't think that program exists. It becomes
>evident after using the 373 for awhile that a program that would either
>circumvent or enhance the algorithm in ABI's analysis program might be a
>useful tool. What do I want this tool to do? 1) Allow me to get inside and
>change the base space number if I want. 2) Figure a way to get around the
>"all DNA is 25%A25%G25%C25%T" problem. These are _easy_ fixes. Others are
>hard. I hear rumours and papers of neural net analysis of this data.
>Anybody out there working on something that looks good? 
> 
>Paul Morrison   Dana1030
>Molecular Biology Core Facility
>Dana Farber Cancer Institute
>44 Binney Street
>Boston, MA 02115

Hi,
	Sorry to include all of the above with this reply but thought
the thread was worth including.  The problem of improving base calling
from the ABI is non-trivial.  We and others have been trying to do just
that for what seems like years now.  ABI also has been working on the
problem for quite a while also and I'd look for something to surface
soon.  The bottom line is THERE ARE NO "_easy_ fixes" to this problem.
	Clark Tibbets at Vanderbilt has done lots of work with neural
nets for DNA sequence analysis and demonstrated a working version of
his program at the Hilton Head Genome Sequencing meeting just last week.
He's published extensively on the subject and his papers make interesting
reading.  He's trained a neural net to develop the algorithms that allow
for (according to what I saw) more accurate (when compared to ABI's) base
calls within the range from the priming site out to about 400 bases.  It's
pretty cool stuff and he may have something there.
	Several other groups have looked at the ABI-lane files, and allow
one to proof read the data once ABI has manipulated it.  Sequencher, 
DNAStar, and SeqEd are three programs on the Mac that allow the user to
re-interpret the data (as discussed by others).  On the SunSparcStation,
the Staden, et al TED (trace editor) and XBAP also allow such manipulations.
These 4 programs all provide the user with access to already manipulated
data and make changes they feel are appropriate.
	As for dealing with the raw-raw data (the approx. 20 meg gel file),
the new ABI Analysis program, Clark's program, our program (which is not yet
ready for prime time), and others which are at even earlier stages, may
produce something that is better than the existing ABI Analysis program.
I could go on almost forever with the list of issues that need to be
addressed before a new and improved base calling algorithm becomes available.
The major bottleneck is that the sample spacing eventually reaches a point
where more than one band is in the window at the same time.  This causes
problems in assigning base calls at longer read lengths, especially when
the signal is usually lower the further out you get.  Longer gel plates
and a more focussed lens can help resolve this data and several years
ago I presented data at the Cold Spring Harbor Human Genome meeting showing
data that was manually read-able out to around 750 bases using 60 cm plates
and a 2x more focussed lens.  ABI now has come out with a lowered optical
stage, is testing longer gel plates, and attempting to improve their
base calling algorithm.  Data presented at the Hilton Head meeting was
very exciting.
	So things along this line are moving, slowly but still moving
forward.  Hang in there and in the future (hope sooner than later),
some better base calling options will become available.  In the mean
time, you could contact ABI and obtain their "tool-kit" that is an object
library that will allow you to manipulate the data yourself.  It's free
but you have to sign an agreement with them not to distribute your code.
You also could contact Clark and get a copy of his neural net program.

	Cheers to one and all.........bruce
  - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
 \  Bruce A. Roe                 Professor of Chemistry and Biochemistry /
 /  Dept. of Chem. and Biochem.  INTERNET: BROE@aardvark.ucs.uoknor.edu  \
 \  University of Oklahoma       BITNET:   BROE@uokucsvx                 /
 /  620 Parrington Oval, Rm 208  AT&TNET:  405-325-4912 or 405-325-7610  \
 \  Norman, Oklahoma 73019       FAXnet:   405-325-6111                  /
  - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!uunet!mnemosyne.cs.du.edu!nyx!cagrant
From: cagrant@nyx.cs.du.edu (Clinton Grant)
Newsgroups: bionet.software
Subject: Software manipulation of ABI 373a traces
Keywords: 373a ABI sequenceing
Message-ID: <1993Nov1.215442.25113@mnemosyne.cs.du.edu>
Date: 1 Nov 93 21:54:42 GMT
Sender: usenet@mnemosyne.cs.du.edu (netnews admin account)
Organization: Nyx, Public Access Unix at U. of Denver Math/CS dept.
Lines: 10
X-Disclaimer: Nyx is a public access Unix system run by the University
 	of Denver for the Denver community.  The University has neither
 	control over nor responsibility for the opinions of users.

Greetings,
	I'm interested in hearing how people are using ABI traces in 
presentations. Specifically, what is the best software to use when making 
annotations to gel traces. What software are you using to capture and work
on the traces? Are you working on a Mac or an IBM etc? We have access to PC's, 
Mac's and colour printers.

Any comments would be appreciated.

Clint.

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!daresbury!news
From: W.Chen@de.dkfz-heidelberg (Weiyun Chen)
Newsgroups: bionet.software
Subject: POSITIONS IN SOFTWARE DEVELOPMENT
Message-ID: <1993Nov2.120739.1728@gserv1.dl.ac.uk>
Date: 2 Nov 93 12:04:41 GMT
Sender: dok419@cvx12.inet.dkfz-heidelberg.de
Distribution: bionet
Lines: 32
Content-Type: text/plain; charset=US-ASCII
Precedence: first-class
Original-To: emb-gen@uk.ac.daresbury
Content-Transfer-Encoding: 7bit
Mime-Version: 1.0
Original-Cc: bio-software@uk.ac.daresbury
X-Mailer: ELM [version 2.4 PL21]
Content-Length: 1141




POSITIONS FOR SOFTWARE DEVELOPERS AT THE GERMAN 
CANCER RESEARCH CENTER (DKFZ), HEIDELBERG

Positions for programmers are available at the Department
of Molecular Biohysics (0810) of DKFZ starting from January 1993
for two years (continuation will depend on external grants).

DKFZ is participating in several national and international
bioinformatics projects and hosts the European Data Resource
for Human Genome Research and the German node of EMBnet. You
would work in a team on the development of an integrated information
management system for the Human Genome Project.

Good working knowledge of UNIX, X11, C or C++ is required, as well
as experience in at least one of the following areas: relational or
object-oriented database programming, GUI development, Smalltalk, 
logic programming. Interest in molecular biology or genetics will be
an advantage.

Salaries will fall within the German BAT IIa group.

Applicants should send their cv, history of experience, and two 
references to the

        Personnel Department,
	Reference No. 100/93, 
        DKFZ,
        Im Neuenheimer Feld 280,
        D-69120 Heidelberg, Germany

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!daresbury!news
From: daj@uk.ac.ic.nhm ((David Johnston) daj)
Newsgroups: bionet.software
Subject: Trace editors for the Mac and other stuff
Message-ID: <1993Nov2.100117.2722@gserv1.dl.ac.uk>
Date: 2 Nov 93 10:37:44 GMT
Sender: list-admin@daresbury.ac.uk
Distribution: bionet
Lines: 62
Precedence: first-class
Original-To: bio-software@uk.ac.daresbury
X-Popmail-Charset: British

Sorry this is a bit long but here goes:

Bruce Roe's comments on the above yesterday, and especially the problems of 
getting longer sequences from the ABI sequencer got me thinking.

Much of our sequencing is "into the unknown"" rather than routine and 
so the rate limiting factor is not the speed of gel reading but the speed 
with which we can get the next oligo made. Hence it is vital that we 
maximise read length from any reaction set. We have extensively played 
with mannual sequencing to optimise this. Sequenase sequencing using both 
manganease and extension mix in the reaction labels well and evenly from 
approx 10 to 2000 plus bases from the primer and Hydrolink Long Ranger gels 
maintain good tight bands (albeit closely spaced) up to at least 750 bases 
from primer (best read to date).

When I was looking to select an automated sequencer, read length was a 
significant factor. Because I knew what was possible from manual 
sequencing, I asked the ABI guys about the flexibility of electrophoresis 
on the 373A and was basically told that, since the bands must pass the 
detection zone at a fixed rate (12+-2 laser scans per band), you did 
electrophoresis how they told you to do it or it wouldn't work and that was 
it. Ie. They were not interested in getting longer reads. Since, if current 
adverts are to be believed, both LKB and LiCor are way ahead of ABI on this 
score, this seemed an extreemly short sighted attitude. All power, 
therefore, to Bruce and his collegues who are trying to improve matters but 
I do wonder if there might be an "easier" way. 

Point 1: I know that reactions can be made good for a couple of thousand 
bases

Point 2: the standard ABI base calling algorithm works (or you wouldn't 
get any sequence at all)

Point 3: surely then, we should be looking not to make the algorithms even 
more complicated (and thus vunerable) than they are at the moment but to 
improve the electrophoresis conditions so as to be able to better space the 
bands that are far from the primer.

LKB make extensive use of Hydolink Long Ranger gels in the ALF which 
presumably must help acheive their long reads. The problem with 
these gels is that you usually run them more slowly than standard gels 
(hence the scans/band problem). Has anyone out there in 373A land tried any 
of the following to increase read length:

Long Ranger gels run slow or fast (by altering electrical supply and/or 
buffer concentration or gradient)

Composite gels with standard acrylamide in the detection zone (so bands 
pass through it at the correct rate) and Long Ranger above (to keep the 
bands tight), or gradients of the 2 forms of acrylamide.

or anything else on the electrophoresis front

My 2 cents worth, 


Cheers,
DAJ
David A. Johnston
Dept of Zoology, The Natural History Museum, Cromwell Road,
South Kensington, London SW7 5DB.
(tel 071 9389297, fax 071 9388754, email daj@nhm.ic.ac.uk)

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!rainer-mac.embl-heidelberg.de!user
From: Fuchs@EMBL-Heidelberg.DE (Rainer Fuchs)
Newsgroups: bionet.software
Subject: Mail server utility available
Message-ID: <Fuchs-011193170900@rainer-mac.embl-heidelberg.de>
Date: 1 Nov 93 16:09:00 GMT
Followup-To: bionet.software
Organization: EMBL Data Library
Lines: 29
Nntp-Posting-Host: rainer-mac.embl-heidelberg.de

A new utility program called MSU (mail server utility) is available that
assists scientists in using electronic mail servers for sequence analysis,
such as BLITZ, BLAST, GRAIL, etc. It is written in standard C and runs on
various OpenVMS and UNIX platforms.

In contrast to existing similar tools, MSU takes its knowledge about the
request format a server expects from an external service description file.
There's no in-built, hard-wired knowledge. This approach makes MSU
extremely flexible and allows easy modification, extension and
customisation.

MSU is distributed with a default specification file that defines about
twenty email services. New services can be added easily as they come up.
When MSU starts up, it reads this file and creates a menu system which
guides the user through the process of producing a well-formed service
request. Additional options include the downloading of help files and the
registration with services that require it prior to use. Most popular
sequence formats are supported.

Copies can be obtained from ftp.embl-heidelberg.de
(/pub/software/unix/msu.tar.Z and /pub/software/vax/msu.uue) or by email
from netserv@embl-heidelberg.de ("get  unix_software:msu.uue" or "get
vax_software:msu.uue").

-- 

Rainer Fuchs
EMBL Data Library
Fuchs@EMBL-Heidelberg.DE

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!CS.Arizona.EDU!organpipe.uug.arizona.edu!uunet!mcsun!sun4nl!news.sara.nl!HASARA11.SARA.NL!A428ENDE
From: A428ENDE@HASARA11.SARA.NL
Newsgroups: bionet.software
Subject: Re: Calculating codon usage
Message-ID: <16C7A78A1.A428ENDE@HASARA11.SARA.NL>
Date: 2 Nov 93 16:55:10 GMT
References: <16C76CBAES85.MYGALP01@ulkyvm.louisville.edu>
Organization: S.A.R.A. Academic Computing Services Amsterdam
Lines: 21
Nntp-Posting-Host: vm1.sara.nl
X-Newsreader: NNR/VM S_1.3.2

In article <16C76CBAES85.MYGALP01@ulkyvm.louisville.edu>
MYGALP01@ulkyvm.louisville.edu writes:
 
> Hi,
> I haven't found the codon usage table for Streptococcus on IUBio or EMBL
> servers and probably will need to construct one myself. However, I don't know
> of any program to do, other than one in the GCG package. Does anybody have
> any shareware that will calculate the codon usage at least for a given gene?
 
A while ago somebody else asked the same. I have a TurboPascal unit and some pr
ograms which can do the job quickly, but dirty (it is not very user friendly).
I offered to translate the code and sample programs to englisch and I am almost
finished. The program is capable of extracting exon information from the featur
e table of EMBL sequences. You must have TurboPascal 5.0 or higher (lower isn't
 tested but would probaly work, because there isn't anything fancy in it). If y
ou want I can mail the source to you or to this group if somebody can explain t
o me how to do it.
It probaly takes another two weeks because I'll write an small docfile to expla
in what it is doing and my english isn't that good.
Henk van de Kamer
CHLAMY@SARA.NL

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!UVVM.UVIC.CA!JCOWARD
From: JCOWARD@UVVM.UVIC.CA
Newsgroups: bionet.software
Subject: ITCH'94 - STUDENT POSTER CONTEST
Message-ID: <9311012356.AA06625@net.bio.net>
Date: 1 Nov 93 22:23:41 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 57


ITCH'94 - INFORMATION TECHNOLOGY IN COMMUNITY HEALTH
Victoria, B.C. Canada: October 30 - November 3, 1994.


           STUDENT PAPER (POSTER) COMPETITION

 Open to students in disciplines with a Community Health
 Informatics component. Prize = $500 & Registration Fee.

The Conference on Information Technology in Community
Health (ITCH'94) invites you to submit a paper for its
2nd. student poster session and competition, sponsored
by Metro-McNair Clinical Laboratories Limited.  It is
an ideal opportunity to meet and show your work to an
international group of specialists working in areas of
community health and information systems.

ELIGIBILITY:   The author must be a full time student
registered in a program of a recognized post-secondary
academic institution during 1994.

SUBJECT:         Any recently completed project (major
course project, directed study, work-term research, etc.)
related to informatics applications in community health
care.  Topics/issues range from available/appropriate
technologies, specific/specialized software and policy
applications.  (n.b. "community health" is meant to have
the broadest of interpretations - from acute care, to
home care, to health promotion, to research and education)

DEADLINE FOR PAPERS:    MAY 15, 1994

SUBMISSION:  A maximum of six pages that includes; the
title, the author's name and school affiliation, an
abstract of less than 200 words, and introduction
(background of the work), the body of the paper, a
discussion and conclusion (your own thoughts/ideas
on your subject) and numbered references (no footnotes).

The winning paper will be selected by a panel of judges
on the basis of originality, academic and scientific merit,
and presentation.  The author of the winning poster will
receive a $500 cash prize and full conference registration.

SEND ALL SUBMISSIONS TO: Gail Peterson, ITCH'94
                         School of Health Information Science
                         University of Victoria, PO Box 3050
                         Victoria, B.C., Canada - V8W 3P5

FOR INFORMATION VIA E-MAIL:

JAMES H. COWARD, CHE
ITCH'94 - INFORMATION TECHNOLOGY IN COMMUNITY HEALTH
ORGANIZING COMMITTEE, SPONSORS AND EXHIBITORS,
220, 1641 Hillside Avenue, Victoria BC  V8T 5G1
PHONE: (604) 598-3681  FAX: (604) 592-6341

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!SANGER.OTAGO.AC.NZ!peter
From: peter@SANGER.OTAGO.AC.NZ (Peter Stockwell)
Newsgroups: bionet.software
Subject: Re: unarchiving pc files
Message-ID: <9310312219.AA20855@net.bio.net>
Date: 31 Oct 93 20:42:07 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 28

Sarah Tilley (sjt@newt.phys.unsw.edu.au) wrote:

> Keywords:

> --
> Hi,

> I have just obtained some public domain files for my pc by ftp. They are of th
e format *.exe, and they are meant to automatically unarchive themselves to give
 me the programs I have downloaded. However whenever I type the filename all I g
et is a screen and keyboard freeze-up. Should I be unarchiving them on my unix m
achine? How do I get at these files? I am even having problems unarchiving pkunz
ip! Help! I have a directory full of software I want to use but can't get at.
> Thanks in advance,

> **
> Sarah Tilley
> sjt@newt.phys.unsw.edu.au


Also make sure you obtained those files from a directory of files
for PC.
Another hint: try decompression on another PC (although very unlikely,
but it CAN be a problem with your configuration).

Wagner Fotnes
Brazilian Center of Protein Sequencing
University of Brasilia - Brazil

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!uni-heidelberg!rz.uni-karlsruhe.de!xlink.net!howland.reston.ans.net!pipex!uunet!spcuna!spcvxb!thomas_l
From: thomas_l@spcvxb.spc.edu (Larry Thomas, Mathematics Faculty)
Newsgroups: bionet.software
Subject: Malaria program
Message-ID: <1993Nov2.155611.1@spcvxb.spc.edu>
Date: 2 Nov 93 20:56:11 GMT
Sender: news@spcuna.spc.edu (Network News)
Organization: St. Peter's College, US
Lines: 5
Nntp-Posting-Host: spcvxa.spc.edu

A colleague had (but somehow messed up) a public domain program that
simulated the effects of various methods of controlling the spread
of malaria. Apparantly the program was widely disseminated a few
years ago. The program is intended for classroom use. Does anyone
know where it can be found? We need a DOS version.  Thanks.

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!NBRF.GEORGETOWN.EDU!POSTMASTER
From: POSTMASTER@NBRF.GEORGETOWN.EDU
Newsgroups: bionet.software
Subject: Re: PIR/GCG
Message-ID: <01H4U7I30D529EEGRO@NBRF.Georgetown.Edu>
Date: 2 Nov 93 17:01:40 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 111

In message <9310301907.AA04875@net.bio.net> posted to Bio-Soft Jean-Loup Risler
wrote:

> Up to now I received the PIR database from MIPS on a magtape. Like many many
> others, I had troubles with the GCG files provided on the tape, which were
> fixed by re-running DBINDEX.
> 
> Now I receive PIR on their CD-ROM. Since I want to use GCG, I have to copy
> the files onto my VAX/VMS. *NOTE* this was a pain in the neck, a CD_MOUNT
> followed by a COPY doesn't work because the resulting file are "undefined".
> The CD_ACCESS program from P. Stockwell, available from the EMBL server,
> doesn't work either on these CD-ROMs (it's the only case I know of).
> 
> You MUST mount the CD-ROM with the following command:
> 
> CD_MOUNT/media=cdrom/UNDEFINED=(STREAM_LF:512)
> 
> It was rather hard to be aware of the UNDEFINED switch ... this may be
> useful to other people...
> 
> Well, finally it worked. The .REF and .SEQ files seem to be OK. Now, if I
> run PIRTOGCG or DBINDEX, I get the following message for *ALL* the
> sequences:
> 
> * no accession number for sequence XXXX *
> 
> Anyway the programs go on, I get the usual .NAMES, .OFFSET, etc...files
> whose size seem reasonable.
> 
> *BUT* I can't FETCH any sequence. If I try to fetch CCHU from PIR1, for
> example, I get  * no files in PIR1:CCHU *  .....
> 
> NOTE 1: I am lazy and I always wait for a certain time before installing the
> minor releases, waiting for other people to find the new bugs ... :-)
> Hence I'm still under GCG #7.0  Is this the reason?
> 
> NOTE 2: The files are NOT in CODATA format. They just look like the good
> old PIR files. However, the accession number is hidden in a line such as:
> c;Accession: xxxxxx

As we understand it you would like to use the GCG sequence analysis package
with the CD-ROM.  Although the ATLAS package is designed to be a standalone
database query/retreival system, the data may be used in conjunction with other
applications.  This summarizes the procedure we believe you are looking for.

Since the GCG index files do not exist on the CD you must off-load all data
files to disk and create the necessary auxiliary files.  The CD_ACCESS program
should work, but after in-house testing we have determined that it does not.
Apparently the CD format is incompatible with our specifications; we are
discussing this issue with the CD publisher.

In order to copy files from the CD to disk one must use the CD_MOUNT command
with the UNDEFINED_FAT (for non-VMS users that is "undefined file access type"
:-) qualifier as you have discovered.  Two types of files can be retrieved:

1) binary files (PIR1.INX, TERM.TDX)
  If you want the BINARY files such as PIR1.INX, use the following CD_MOUNT
  command with no further file modifications but substituting the correct
  device name for your CD-ROM:
    $ CD_MOUNT/MEDIA=CDROM/UNDEFINED_FAT=(FIXED:NONE:512) $1$dka100:

2) ASCII files (PIR1.SEQ, PIR1.REF)
  The process of downloading ASCII files is a little more complicated.
  The files MUST end up in their native format with the following file
  attributes:
    Record format:      Variable length, maximum XXX bytes
    Record attributes:  Carriage return carriage control
  where XXX is "490" for a .SEQ file and "500" for a .REF file depending on
  the PIR release.  After copying the files from CD, the DCL CONVERT command
  must be used to create files with the proper attributes.  The following is
  an FDL file describing the resulting file after using the CONVERT utility.
  Extract this file between the "----cut here----" marks (exclusive) and call
  it PIRCD.FDL.

----------------------------------cut here-----------------------------------
IDENT	"27-JAN-1993 13:30:42   VAX-11 FDL Editor"

RECORD
	CARRIAGE_CONTROL	carriage_return
	FORMAT			variable
----------------------------------cut here-----------------------------------

  Protocol:
    a) $ CD_MOUNT/MEDIA=CDROM/UNDEFINED_FAT=(STREAM:500) $1$dka100:
!! DO _NOT_ USE "STREAM_LF" !!
    b) $ COPY $1$dka100:[DATA.NBR]PIR1.SEQ PIR1.SEQTMP
       $ COPY $1$dka100:[DATA.NBR]PIR1.REF PIR1.REFTMP
       ...
    c) $ CONVERT/FDL=PIRCD.FDL PIR1.SEQTMP PIR1.SEQ
       $ CONVERT/FDL=PIRCD.FDL PIR1.REFTMP PIR1.REF
       ...
    d) $ CD_DISMOUNT $1$dka100:

  After this procedure use the DCL command DIRECTORY/FULL to make certain the
  ASCII files have the proper file attributes.

Please use the above protocols and report any problems to us.  We appreciate
notification of a problem with the ATLAS product.  If you like, we will supply
you with a detailed DCL COMMAND procedure to facilitate file manipulation for
future releases.
------------------------------------------------------------------------
                                 Christopher Marzec
                                 MARZEC@NBRF.Georgetown.Edu

                                 Dr. John S. Garavelli
                                 Database Coordinator
                                 Protein Information Resource
                                 National Biomedical Research Foundation
                                 Washington, DC  20007
                                 POSTMAST@GUNBRF.BITNET
                                 POSTMASTER@NBRF.GEORGETOWN.EDU

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!d.love
From: d.love@dl.ac.uk (Dave Love)
Newsgroups: bionet.software
Subject: Re: ccp4 mailing list
Message-ID: <D.LOVE.93Nov2193440@dlpx1.dl.ac.uk>
Date: 2 Nov 93 19:34:39 GMT
References: <12150E3280201597@dccc.med.umn.edu>
Reply-To: ccp4@uk.ac.daresbury
Distribution: bionet
Organization: SERC Daresbury Laboratory, Warrington, UK
Lines: 29
NNTP-Posting-Host: dlpx1.dl.ac.uk
In-reply-to: HOEFFNER@DCCC.MED.UMN.EDU's message of 26 Oct 93 03:52:00 GMT

>>>>> On 26 Oct 93 03:52:00 GMT, HOEFFNER@DCCC.MED.UMN.EDU said:

 Ed> Would someone please tell me how to get on the ccp4 mailing
 Ed> list. Many thanks.

Since I gather others enquired: The approved way for the e-mail (not
paper) list is to send
 sub ccp4bb
to ccp4bb-requests@dl.ac.uk
                 ^
which will be serviced by a daemon.  Problems to the address below if
all else fails.

>>>>> On 26 Oct 93 10:31:26 GMT, vinz@PCLSP2.KUICR.KYOTO-U.AC.JP (Vinz-san) said:

 Vinz-san> could you please somebody explain to me what is ccp4 mailing list???

It's related to the CCP4 protein crystallography software recently
mentioned here. (ftp to ccp4.dl.ac.uk)

--Dave (not the secretary)
--

Thank you for your interest in the CCP4 protein crystallography programs.

 Secretary to CCP4         | Telephone: (+44) 925 603530  (direct line) 
 SERC Daresbury Laboratory |            (+44) 925 603000  (switchboard)
 Warrington WA4 4AD        | Facsimile: (+44) 925 603174
 UK                        | e-mail:    ccp4@daresbury.ac.uk

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!rc1!ub4b!mcsun!uunet!noc.near.net!saturn.caps.maine.edu!maine.maine.edu!rroxby
From: RROXBY@MAINE.MAINE.EDU (Robert Roxby)
Newsgroups: bionet.software
Subject: How do you subscribe to this group?
Message-ID: <93306.113830RROXBY@MAINE.MAINE.EDU>
Date: 2 Nov 93 16:38:30 GMT
Organization: University of Maine System
Lines: 2

Thanks.
Bob Roxby

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!CS.Arizona.EDU!organpipe.uug.arizona.edu!news
From: sfm@manduca.neurobio.arizona.edu (Stephen Matheson)
Newsgroups: bionet.software
Subject: Re: Calculating codon usage
Message-ID: <2b67k9$p2p@organpipe.uug.arizona.edu>
Date: 2 Nov 93 18:07:05 GMT
References: <16C76CBAES85.MYGALP01@ulkyvm.louisville.edu>
Organization: University of Arizona UNIX Users Group
Lines: 47
NNTP-Posting-Host: manduca.neurobio.arizona.edu

From article <16C76CBAES85.MYGALP01@ulkyvm.louisville.edu>,
by MYGALP01@ulkyvm.louisville.edu:

> I haven't found the codon usage table for Streptococcus on IUBio or EMBL
> servers and probably will need to construct one myself. However, I don't
> know of any program to do, other than one in the GCG package. Does
> anybody have any shareware that will calculate the codon usage at least
> for a given gene?

I have a simple program written in QBasic (comes with DOS 5 & 6).  It
extracts the amino acid and nucleic acid sequences from GenBank records
obtained via the RETRIEVE E-Mail Server (retrieve@ncbi.nlm.nih.gov);
I assume that this format would exist in any GenBank report.

The input consists of a text file containing GenBank records.  No editing
of a RETRIEVE report containing GenBank records is necessary, unless the
format has been altered or if the report contains untranslated sequences
(i.e., records with nucleic acid sequence but no amino acid sequence).
The input must be in the original GenBank format.

The output of the program is to a text file that can be printed via
any word processor (the output is designed to be printed in landscape
orientation; minor editing of the text file would enable one to print
in portrait orientation).  The program translates the nucleic acid
sequence as it reads in and tabulates the codons, then compares the
translation with the reported amino acid sequence.  This serves as a
sort of error checker.  At this time, unfortunately, the program is
unable to assemble complete messages from exons.  This, however, should
be easy to accomplish with fairly minor additions to the code.  For now,
the program skips any gene whose CDS entry begins with the word "join".
This limitation can be circumvented by editing the input file to exclude
exons from the nucleic acid sequence (using the "join" information as
a guide, then editing the CDS entry to reflect the new position of the
coding sequence.

I'm working on a more sophisticated version of this program, using
Visual Basic, and intend to have a stand-alone DOS program ready in
a few months.

If there is any interest in this program, I'll be happy to uuencode
it and post it and/or distribute it via Email.  If it isn't already
obvious, I'll make it clear that I'm an amateur programmer, so...
buyer beware.
--

Steve Matheson   Program in Neuroscience   University of Arizona
sfm@neurobio.arizona.edu

From owner-software@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!CS.Arizona.EDU!organpipe.uug.arizona.edu!uunet!pipex!uknet!pavo.csi.cam.ac.uk!webmac9.vrl.path.cam.ac.uk!user
From: ps10000@mbuc.bio.cam.ac.uk (Peter Speck)
Newsgroups: bionet.software
Subject: histone association
Message-ID: <ps10000-021193102738@webmac9.vrl.path.cam.ac.uk>
Date: 2 Nov 93 10:27:45 GMT
Sender: news@infodev.cam.ac.uk (USENET news)
Followup-To: bionet.software
Organization: Div. Virology, Cambridge, UK
Lines: 3
Nntp-Posting-Host: webmac9.vrl.path.cam.ac.uk

I've heard that there is software available that will predict whether a
given DNA sequence will or will not associate with histone proteins.  Does
anyone know what this software is called and where I can get it?  Thanks.

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.software
Subject: URGENT: DEADLINE CHANGE FOR WORLD CONGRESS
Message-ID: <9311031736.AA08868@morpheus.chpc.utexas.edu>
Date: 3 Nov 93 17:36:47 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 68


		   UPDATE ON DEADLINES
FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE, PUBLIC
	     HEALTH, AND BIOTECHNOLOGY
		    24-28 April 1994
                   Hyatt Regency Hotel
                     Austin, Texas
----- (Feel Free To Cross Post This Announcement) ----

Due to a confusion in the electronic distribution of
the congress announcement and deadlines, as well as 
incorrect deadlines appearing in a number of society
newsletters and journals, we are extending the abstract
submission deadline for this congress to 31 December 1993.
We apologize to those who were confused over the differing
deadline announcements and hope that this change will
allow everyone to participate. For congress details:

To contact the congress organizers for any reason use any of the
following pathways:

ELECTRONIC MAIL - compmed94@chpc.utexas.edu

FAX (USA)       - (512) 471-2445

PHONE (USA)     - (512) 471-2472

GOPHER: log into the University of Texas System-CHPC
select the Computational Medicine and Allied Health
menu choice

ANONYMOUS FTP: ftp.chpc.utexas.edu
	     cd /pub/compmed94
	(all documents and forms are stored here)

POSTAL:
            Compmed 1994
      University of Texas System CHPC
            Balcones Research Center
            10100 Burnet Road, 1.154CMS
            Austin, Texas 78758-4497

SUBMISSION PROCEDURES: Authors must submit 5
copies of a single-page 50-100 word abstract clearly
discussing the topic of their presentation. In
addition, authors must clearly state their choice of
poster, contributed paper, tutorial, exhibit, focused
workshop or birds of a feather group along with a
discussion of their presentation. Abstracts will be
published as part of the preliminary conference
material. To notify the congress organizing committee
that you would like to participate and to be put on
the congress mailing list, please fill out and return
the form that follows this announcement.  You may use
any of the contact methods above. If you wish to
organize a contributed paper session, tutorial
session, focused workshop, or birds of a feather
group, please contact the conference director at
mwitten@chpc.utexas.edu . The abstract may be submitted
electronically to  compmed94@chpc.utexas.edu  or
by mail or fax. There is no official format.


If you need further details, please contact me.

Matthew Witten
Congress Chair
mwitten@chpc.utexas.edu

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!daresbury!ajt
From: ajt@uk.ac.sari.rri (Tony Travis)
Newsgroups: bionet.software
Subject: Re: Mac-to-PC Integration
Message-ID: <1993Nov3.105155.18954@gserv1.dl.ac.uk>
Date: 3 Nov 93 10:46:01 GMT
References: <931130040.~INN-PCAa29501.bionet-news@uk.ac.daresbury>
Sender: list-admin@daresbury.ac.uk
Reply-To: ajt@uk.ac.sari.rri
Distribution: bionet
Organization: Rowett Research Institute
Lines: 32
Apparently-To: <bio-soft@dl.ac.uk>
Precedence: first-class
X-Newsreader: TIN [version 1.2 PL0]

Allen Delaney (allen@ca.ubc.brc.sparc) wrote:
: If what Bill Gates is saying about Windows/NT is true, then replacing
: DOS with NT might be the way to go. Microsoft claims transparent
: networking to Macs, UNIX, OS/2, DOS, Netware ......

Iff all the DOS machines are 386DX or better with at least 12Mb RAM and
100Mb disk space!

: I'd be interested if anyone has had any experience doing this.

In my opinion the widely held view that NT stands for 'NOT TRUE' tells
you all you need to know.  Yes, we have tried NT ...

: We use UNIX servers here, which works quite well, but if you don't have
: any unix machines, you might want to look into this.

We network everything from the feeblest XT to the latest top end Macs
via PCNFS and Netatalk using the Unix filesystem to share files on both
Mac and PC platforms.

I've seen people posting on comp.os.linux to say that they are running
Linux as an NFS server to DOS PCNFS clients.  A 'minimum' configuration
PC for NT would perform well as a Linux NFS server, and run X11 easily.

Linux can be installed from CDROM too ;-)

	Tony.
-- 
Dr. A.J.Travis,                       |  JANET: <ajt@uk.ac.sari.rri>
Rowett Research Institute,            |  other: <ajt@rri.sari.ac.uk>
Greenburn Road, Bucksburn,            |  phone: +44 (0)224 712751
Aberdeen, AB2 9SB. UK.                |    fax: +44 (0)224 715349

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.software
Subject: URGENT: DEADLINE CHANGE FOR WORLD CONGRESS
Message-ID: <9311031731.AA07946@morpheus.chpc.utexas.edu>
Date: 3 Nov 93 17:31:14 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 68


		   UPDATE ON DEADLINES
FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE, PUBLIC
	     HEALTH, AND BIOTECHNOLOGY
		    24-28 April 1994
                   Hyatt Regency Hotel
                     Austin, Texas
----- (Feel Free To Cross Post This Announcement) ----

Due to a confusion in the electronic distribution of
the congress announcement and deadlines, as well as 
incorrect deadlines appearing in a number of society
newsletters and journals, we are extending the abstract
submission deadline for this congress to 31 December 1993.
We apologize to those who were confused over the differing
deadline announcements and hope that this change will
allow everyone to participate. For congress details:

To contact the congress organizers for any reason use any of the
following pathways:

ELECTRONIC MAIL - compmed94@chpc.utexas.edu

FAX (USA)       - (512) 471-2445

PHONE (USA)     - (512) 471-2472

GOPHER: log into the University of Texas System-CHPC
select the Computational Medicine and Allied Health
menu choice

ANONYMOUS FTP: ftp.chpc.utexas.edu
	     cd /pub/compmed94
	(all documents and forms are stored here)

POSTAL:
            Compmed 1994
      University of Texas System CHPC
            Balcones Research Center
            10100 Burnet Road, 1.154CMS
            Austin, Texas 78758-4497

SUBMISSION PROCEDURES: Authors must submit 5
copies of a single-page 50-100 word abstract clearly
discussing the topic of their presentation. In
addition, authors must clearly state their choice of
poster, contributed paper, tutorial, exhibit, focused
workshop or birds of a feather group along with a
discussion of their presentation. Abstracts will be
published as part of the preliminary conference
material. To notify the congress organizing committee
that you would like to participate and to be put on
the congress mailing list, please fill out and return
the form that follows this announcement.  You may use
any of the contact methods above. If you wish to
organize a contributed paper session, tutorial
session, focused workshop, or birds of a feather
group, please contact the conference director at
mwitten@chpc.utexas.edu . The abstract may be submitted
electronically to  compmed94@chpc.utexas.edu  or
by mail or fax. There is no official format.


If you need further details, please contact me.

Matthew Witten
Congress Chair
mwitten@chpc.utexas.edu

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!zeta.bmc.uu.se!corax.udac.uu.se!sunic!pipex!uunet!psinntp!execnet!peter.foiles
From: peter.foiles@execnet.com (Peter Foiles)
Newsgroups: bionet.software
Subject: Genbank Search software
Message-ID: <1.4467.570.0NB42ACB@execnet.com>
Date: 2 Nov 93 20:06:00 GMT
Organization: The Executive Network Information System
Lines: 12

Hello ALL!

I would like some information on PC based software that is available for 
 searching the Genbank database on CD-ROM. We have been using the IBI 
Pustel program but it apparently is not compatible with the Genbank data 
on CD-ROM. The commercial software we have found so far has been 
prohibitively expensive. Any suggestions would be greately appreciated.

==Peter Foiles, PhD==

---
~ CmpQwk #UNREG~ UNREGISTERED EVALUATION COPY

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!uni-heidelberg!xlink.net!howland.reston.ans.net!agate!spool.mu.edu!umn.edu!lynx.unm.edu!triton.unm.edu!news-user
From: dkim@unm.edu
Newsgroups: bionet.software
Subject: Re: unarchiving pc files
Message-ID: <2b6k44$ebm@triton.unm.edu>
Date: 2 Nov 93 21:40:20 GMT
References: <9310312219.AA20855@net.bio.net>
Organization: University of New Mexico, Albuquerque
Lines: 15
NNTP-Posting-Host: triton.unm.edu






Sender: kim@flovax.lanl.gov (Daniel Kim)
Followup-To: 
Distribution: bionet
Organization: University of New Mexico, Albuquerque
Keywords: 
Cc: 

You may also have inadvertantly transferred the files in ASCII mode
instead of Binary.  Try getting them again, but specify binary
transfer.   Daniel KiM

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!lhc!darwin.sura.net!howland.reston.ans.net!usenet.ins.cwru.edu!agate!spool.mu.edu!olivea!decwrl!decwrl!morrow.stanford.edu!morrow.stanford.edu!not-for-mail
From: HF.JSL@forsythe.stanford.edu (Joseph Lipsick)
Newsgroups: bionet.software
Subject: Re: Genbank Search software
Message-ID: <2b7n7h$amh@morrow.stanford.edu>
Date: 3 Nov 93 07:39:29 GMT
Sender: news@morrow.stanford.edu
Distribution: usa
Organization: Stanford University
Lines: 31
NNTP-Posting-Host: morrow.stanford.edu

In article <1.4467.570.0NB42ACB@execnet.com>,
peter.foiles@execnet.com (Peter Foiles) writes:
>Hello ALL!
>
>I would like some information on PC based software that is available for
> searching the Genbank database on CD-ROM. We have been using the IBI
>Pustel program but it apparently is not compatible with the Genbank data
>on CD-ROM. The commercial software we have found so far has been
>prohibitively expensive. Any suggestions would be greately appreciated.
>
>==Peter Foiles, PhD==

I would recommend that you use the NCBI resources.  There is a

great CD-ROM Genbank/Medline suite called ENTREZ that is available
for the price of the plastic alone.  Updates are available quarterly
I think.  For that up-to-the-minute search, the Genbank resource can
be searched by e-mail using BLAST and interesting sequences can be
retrieved using RETRIEVE.  Both of these are free.  For information
on BLAST and RETRIEVE, send a "help" message to:
BLAST@ncbi.nlm.nih.gov or RETRIEVE@ncbi.nlm.nih.gov

There is also a great local homology program for protein sequences
called MACAW that is also available from NCBI by FTP.  I strongly
urge people to use these valuable resources and acknowledge them
properly.  A number of years ago there was a useful BIONET resource
that was discontinued by the NIH and not enough people complained.

Use it or lose it...

Joe Lipsick

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!rc1!ub4b!mcsun!uknet!pipex!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!csulb.edu!csus.edu!netcom.com!biodata.slip.netcom.com!vern
From: vern@BioData.COM (Vernon Keenan)
Newsgroups: bionet.software
Subject: Re: Mac-to-PC Integration
Message-ID: <netnewsCFxHvs.Lt1@netcom.com>
Date: 3 Nov 93 18:26:14 GMT
References: <netnewsCFFqz0.5r6@netcom.com>
Sender: netnews@netcom.com (USENET Administration)
Organization: BioData, Inc.
Lines: 16
X-Xxmessage-Id: <A8FD37852F02A72C@biodata.slip.netcom.com>
X-Xxdate: Wed, 3 Nov 93 18:25:09 GMT
X-Useragent: Version 1.1.3

In article <netnewsCFFqz0.5r6@netcom.com> Vernon Keenan, vern@BioData.COM
writes:
>However, the memory requirements of PhoneNET Talk are great...over 100Kb
>of the precious 640Kb DOS low memory. Depending on your hardware's memory
>configuration and BIOS, you can reduce the memory overhead, but you can't
>count on more than 500Kb for DOS applications. This causes problems with
>many data acquisition programs.

I've been informed by a colleague that PhoneNET Talk PC will run in as
little as 40Kb RAM when using DOS 6.0 and MemMaker. That should give you
about 580Kb RAM for applications, which should be OK for a lot of people.

If you have a Mac-centric network, and you need to get PCs transfering
data, then I would take a look at Farallon's PhoneNET PC product.

Vern

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!rc1!ub4b!mcsun!uknet!pipex!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!csulb.edu!csus.edu!netcom.com!biodata.slip.netcom.com!vern
From: vern@BioData.COM (Vernon Keenan)
Newsgroups: bionet.software
Subject: Re: Mac-to-PC Integration
Message-ID: <netnewsCFxHr6.Lq7@netcom.com>
Date: 3 Nov 93 18:23:29 GMT
References: <netnewsCFFqz0.5r6@netcom.com>
Sender: netnews@netcom.com (USENET Administration)
Organization: BioData, Inc.
Lines: 22
X-Xxmessage-Id: <A8FD36DF2601A72C@biodata.slip.netcom.com>
X-Xxdate: Wed, 3 Nov 93 18:22:23 GMT
X-Useragent: Version 1.1.3

In article <1993Nov2.192140.13539@brc.ubc.ca> Allen Delaney,
allen@sparc.brc.ubc.ca writes:
>If what Bill Gates is saying about Windows/NT is true, then replacing
>DOS with NT might be the way to go. Microsoft claims transparent
>networking to Macs, UNIX, OS/2, DOS, Netware ......
>
>I'd be interested if anyone has had any experience doing this.
>

The way I understand NT, you need an NT Advanced Server to get all this
integration. Based on what I've heard about the performance pentalty of
running DOS and Windows apps on NT Client (as poor as 50% compared to
Win3.1), I'm not terribly excited about NT for now. 

Vern
***************************************************************
| Vernon Keenan                  | Voice:    415-513-8940     |
| President                      | Fax:      415-312-8086     |
| BioData, Inc.                  | Internet: vern@BioData.COM |
| 1826 S. Grant St. Suite 620    |                            |
| San Mateo, California 94402    |                            |
***************************************************************

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!uni-heidelberg!rz.uni-karlsruhe.de!xlink.net!howland.reston.ans.net!
 sol.ctr.columbia.edu!hamblin.math.byu.edu!news.byu.edu!cwis.isu.edu!u.cc.utah.edu!mac64_09.med.utah.edu!stillman
From: stillman@bioscience.utah.edu (David Stillman)
Newsgroups: bionet.software
Subject: MacTetrad6 available - Excel spreadsheet for yeast genetics
Message-ID: <2b8ri5$l6k@u.cc.utah.edu>
Date: 3 Nov 93 17:59:33 GMT
Organization: University of Utah
Lines: 69
NNTP-Posting-Host: mac64_09.med.utah.edu
X-UserAgent:
X-XXMessage-ID: <A8FD3FD01A034009@mac64_09.med.utah.edu>
X-XXDate: Wed, 3 Nov 93 11:00:32 GMT

Hi Netters!

We have updated our MacTetrad Excel spreadsheet designed for tetrad data
for yeast genetics.  One enters the genotypes of haploid spores into the
spreadsheet and a Macro automatically classifies each tetrad as PD, NPD,
or T for each pair of markers.  The data is presented in a table, along
with recombination distances.  

When one is performing a cross with multiple markers segregating, it is
often difficult to identify the spores with a particular genotype.  The
spreadsheet macro makes this procedure simple.  The macro also allows one
to identify tetrads with a particular characteristic (i.e. tetrads that
are NPD for two specific markers).  

Two new features in MacTetrad6:
1. The macro automatically creates your spreadsheet after you enter how
many tetrads and what markers.
2. When searching for spores with a particular genotype, one can use the
"Pull Strains" command to put the desired strains into a new spreadsheet.
 

This spreadsheet requires Excel (version 3.0 or 4.0) for the Macintosh. 
The spreadsheet also works with Excel for Windows running on an IBM PC,
but we have not extensively tested it.  

For Mac Users: The MacTetrad Package was compressed with Stuffit Deluxe
into a self-extracting archive, and this was then binhexed.  The package
is called MacTetrad6.hqx.  
For PC Users: The MacTetrad Package was compressed with PCZIP.  The
package is called MCTETRD6.ZIP. 

The MacTetrad macro, examples, and an instruction manual are available
over the Internet network via Gopher or FTP:

For Gopher, point Gopher to merlot.welch.jhu.edu
Use the "Search the Titles of All Items in this Gopher Hole" command to
search for "MacTetrad"

For anonymous FTP, log onto the  IUBio Archive (Intenet address =
FTP.Bio.Indiana.Edu).
Open up the folder Molbio, and then open up the folder Mac. (The PC
version is in the folder molbio/IBMPC).

The MacTetrad package is also accessible from the Gopher side of the
IUBio Archive, where it is in the IUBio-Software+Data/Molecular
Biology/Mac folder.  (The PC version is in the IBMPC folder, instead of
the Mac folder.)

For those without access to the Internet, MacTetrad is available from
either Jonathan Greene or David Stillman.  Please send a formatted
Macintosh disk to one of the addresses listed below.

Happy Dissecting!

David Stillman
Department of Cellular, Viral and Molecular Biology
University of Utah Medical Center
Salt Lake City, UT 84132

e-mail:  stillman@bioscience.utah.edu


Dr. Jon Greene
Schering-Plough Research Institute
Mail Stop K15-4,4700
2015 Galloping Hill Road
Kenilworth, NJ 07033-0539

e-mail:  jgreene@phantom.com

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!daresbury!mrccrc!news.dcs.warwick.ac.uk!warwick!uknet!pipex!uunet!math.fu-berlin.de!xlink.net!fauern!lrz-muenchen.de!ipp-garching.mpg.de!lmubmac26.biochem.mpg.de!user
From: ibelgaufts@vms.biochem.mpg.de (horst ibelgaufts)
Newsgroups: bionet.software
Subject: EM heteroduplex tracing/drawing programme wanted
Message-ID: <ibelgaufts-031193153228@lmubmac26.biochem.mpg.de>
Date: 3 Nov 93 14:30:02 GMT
Followup-To: bionet.software
Organization: MPI Biochemistry, Munich
Lines: 14
NNTP-Posting-Host: lmubmac26.biochem.mpg.de

Dear netters, Does anyone know of a Macintosh graphic programme that would
allow one to simulate EM pictures of DNA heteroduplices? For this purpose
the programme should be able to tell you the lengths of curved lines/loops.
I know that programmes are available that  allow you to trace EM pictures
and give you lengths of loops and curved lines. What I need is somethings
that tells you the lengths of curved lines/loops while you are drawing
them.
Thanks

Horst Ibelgaufts
Institute of Biochemistry, MPI of Biochemistry
Munich Martinsried, FRG

ULTRA POSSE NEMO OBLIGATUR

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!max.physics.sunysb.edu!psinntp!psinntp!cmcl2!news.ans.net!europa.eng.gtefsd.com!library.ucla.edu!news.mic.ucla.edu!unixg.ubc.ca!brc.ubc.ca!sparc.brc.ubc.ca!allen
From: allen@sparc.brc.ubc.ca (Allen Delaney)
Newsgroups: bionet.software
Subject: Re: Mac-to-PC Integration
Message-ID: <1993Nov2.192140.13539@brc.ubc.ca>
Date: 2 Nov 93 19:21:40 GMT
References: <netnewsCFFqz0.5r6@netcom.com>
Sender: news@brc.ubc.ca
Distribution: brc
Organization: B. R. Centre Ltd.
Lines: 12
Nntp-Posting-Host: sparc

If what Bill Gates is saying about Windows/NT is true, then replacing
DOS with NT might be the way to go. Microsoft claims transparent
networking to Macs, UNIX, OS/2, DOS, Netware ......

I'd be interested if anyone has had any experience doing this.

We use UNIX servers here, which works quite well, but if you don't have
any unix machines, you might want to look into this.

-- 
Allen Delaney (allen@brc.ubc.ca)
Biomedical Research Centre, U.B.C., Vancouver, B.C. Canada, V6T 1Z3

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.software
Subject: URGENT: DEADLINE CHANGE FOR WORLD CONGRESS
Message-ID: <9311031731.AA08086@morpheus.chpc.utexas.edu>
Date: 3 Nov 93 17:31:47 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 68


		   UPDATE ON DEADLINES
FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE, PUBLIC
	     HEALTH, AND BIOTECHNOLOGY
		    24-28 April 1994
                   Hyatt Regency Hotel
                     Austin, Texas
----- (Feel Free To Cross Post This Announcement) ----

Due to a confusion in the electronic distribution of
the congress announcement and deadlines, as well as 
incorrect deadlines appearing in a number of society
newsletters and journals, we are extending the abstract
submission deadline for this congress to 31 December 1993.
We apologize to those who were confused over the differing
deadline announcements and hope that this change will
allow everyone to participate. For congress details:

To contact the congress organizers for any reason use any of the
following pathways:

ELECTRONIC MAIL - compmed94@chpc.utexas.edu

FAX (USA)       - (512) 471-2445

PHONE (USA)     - (512) 471-2472

GOPHER: log into the University of Texas System-CHPC
select the Computational Medicine and Allied Health
menu choice

ANONYMOUS FTP: ftp.chpc.utexas.edu
	     cd /pub/compmed94
	(all documents and forms are stored here)

POSTAL:
            Compmed 1994
      University of Texas System CHPC
            Balcones Research Center
            10100 Burnet Road, 1.154CMS
            Austin, Texas 78758-4497

SUBMISSION PROCEDURES: Authors must submit 5
copies of a single-page 50-100 word abstract clearly
discussing the topic of their presentation. In
addition, authors must clearly state their choice of
poster, contributed paper, tutorial, exhibit, focused
workshop or birds of a feather group along with a
discussion of their presentation. Abstracts will be
published as part of the preliminary conference
material. To notify the congress organizing committee
that you would like to participate and to be put on
the congress mailing list, please fill out and return
the form that follows this announcement.  You may use
any of the contact methods above. If you wish to
organize a contributed paper session, tutorial
session, focused workshop, or birds of a feather
group, please contact the conference director at
mwitten@chpc.utexas.edu . The abstract may be submitted
electronically to  compmed94@chpc.utexas.edu  or
by mail or fax. There is no official format.


If you need further details, please contact me.

Matthew Witten
Congress Chair
mwitten@chpc.utexas.edu

From owner-software@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!kimbark!jm68
From: jm68@midway.uchicago.edu (James R. Mensch Jr.)
Newsgroups: bionet.software
Subject: Re: MACAW
Message-ID: <1993Nov3.203946.24411@midway.uchicago.edu>
Date: 3 Nov 93 20:39:46 GMT
References: <1993Oct20.205320.23537@nlm.nih.gov>
Sender: kristoff@net.bio.net
Reply-To: jm68@midway.uchicago.edu
Distribution: na
Organization: University of Chicago
Lines: 11
Apparently-To: bionet-announce@ncar.ucar.edu

I would like very much to be able to use MACAW, especially as now
available with the Gibb's sampler.  I find, however, that the MACAW
available at ncbi.<etc.> pub/macaw is executables for IBM PCs with 
Windows. How may we who use Macs or unix machines orVAXen obtain this program touse?


-- 
==========================================================================
James R.Mensch Jr.<j-mensch@uchicago.edu> "My opinions are usually my own"
Snail mail: 5841 S. Maryland Ave., MC5058; Chicago IL 60637   POTFB!
==========================================================================

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!swrinde!emory!europa.eng.gtefsd.com!howland.reston.ans.net!ee.und.ac.za!hippo.ru.ac.za!caesar.wits.ac.za!Witsvma.wits.ac.za!030NEILV
From: 030NEILV@Witsvma.wits.ac.za (Neil van der Merwe)
Newsgroups: bionet.software
Subject: Trumpet and winsoc
Message-ID: <16C7CDC3A.030NEILV@Witsvma.wits.ac.za>
Date: 4 Nov 93 14:23:10 GMT
Organization: Wits University
Lines: 5
NNTP-Posting-Host: witsvma.wits.ac.za

Hi,
Can anyone tell me where I can get hold of Trumpet and Winsoc?  I also
need some info on winsoc, as I am totally unfamiliar with it.
Thanks in advance,
Neil

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!nih-csl!jeffs
From: jeffs@elsie.nci.nih.gov (Jeffrey Alan Silverman)
Newsgroups: bionet.software
Subject: cloning software
Summary: cloning software
Message-ID: <1993Nov4.140837.17153@alw.nih.gov>
Date: 4 Nov 93 14:08:37 GMT
References: <1993Oct20.205320.23537@nlm.nih.gov> <1993Nov3.203946.24411@midway.uchicago.edu>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Distribution: na
Organization: National Institutes of Health
Lines: 15

Does anyone know of any software that will figure out a cloning scheme 
automatically if you give it an insert sequence and designate a vector (or
multiple cloning region)?? What I have in mind is to be able to give the
program a sequence, range of interest , choice or orientation and other
"constraints" and then let the computer figure out the best cloning scheme
for selecting compatible enzymes and vectors.  Obviously for many cloning
schemes this is simple but for others it is not but since there is a finite
set of possibilities is should be easy to do by computer. 
So is there a program that does this or something similar?  If not is there
any interest? we are thinking of developing something along these lines.

Thanks

Jeff Silverman
NCI, NIH

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!cornell.edu!mal5
From: mal5@cornell.edu (Muhammad A. Lodhi)
Newsgroups: bionet.software
Subject: dominant RAPD markers
Message-ID: <199311041432.AA19040@postoffice.mail.cornell.edu>
Date: 4 Nov 93 10:37:02 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 17

Dear Friends
        What is the way of differentiating between heterozygous and
homozygous dominant RAPD markers, if any.  I think that may be very helpful
in linkage analysis with pseudotest crosses in woody plants.  This is a
part of the problem that I am facing for linkage analysis that I posted
earlier on this group.
Thanks in advance

============================
Muhammad A. Lodhi
Cornell University,
NYSAES
Geneva, NY 14456
Ph:    315 787 2239
Fax:   315 787 2216
e-mail:mal5@cornell.edu 


From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!nigel.msen.com!yale.edu!cmcl2!netnews!hill
From: hill@mcclb0.med.nyu.edu (John Edward Hill)
Newsgroups: bionet.software.gcg,bionet.software
Subject: <Q> Saving list of hits with Gopher
Message-ID: <hill.1102816919A@netnews.nyu.edu>
Date: 4 Nov 93 16:07:59 GMT
Followup-To: bionet.software.gcg
Organization: Research Computing Resource, Cell Biology, NYUMC
Lines: 12
Xref: biosci bionet.software.gcg:195 bionet.software:6386
NNTP-Posting-Host: mcrcr1.med.nyu.edu
X-Newsreader: VersaTerm Link v1.1

After doing a TurboGopher (Macintosh) search on GenBank (or other
databases), is there a way to save the list of hits as a text file?  I can
see how to print the list and to save it as a Bookmark file, but the only
way I could see to save a text file is to open an individual sequence.

Thanks!

------------------------------------------------------------------------------
John Edward Hill, Ph.D.              Email (Internet): hill@mcclb0.med.nyu.edu
  212-263-7689 (phone)    212-263-7135 (alt. phone)    212-263-8139 (FAX)
Research Computing Resource & Dept. of Cell Biology
NYU Medical Center, 550 First Ave., NY, NY  10016

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!spool.mu.edu!sol.ctr.columbia.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: Digitizer software (measurement not dna gels) for mac
Message-ID: <CFz90D.5o9@usenet.ucs.indiana.edu>
Date: 4 Nov 93 17:09:47 GMT
Sender: news@usenet.ucs.indiana.edu (USENET News System)
Organization: Biology, Indiana University - Bloomington
Lines: 24
Nntp-Posting-Host: sunflower.bio.indiana.edu


Does anyone have suggestions for digitizing software for Macintoshes
(using a CalComp? digitizer board) that would record measurements
of plant parts (projected from slides onto the digitizer pad)?

The person looking knows that Jandel Scientific makes the right
kind of software (expensive) for their (expensive) digitizer. This
is called
  Sigma-Scan 
  (or possibly Sigma-Scan Calibrating File Converter version 3.9)

Any suggested less expensive equivalents for recording measurements
will be appreciated.  I am aware that NIH Image (and such general
graphics programs like Canvas) can meaure images.  But I don't
know details like (a) will Image or others allow meaurements to
be automatically saved into spreadsheet type data files, (b) do
digitizers act like mouse input on Macs so that you don't need special
software for them.

P.S., I did use gopher to iubio archive to search the bionet news first
for previous tips on digitizers.  Only found info on dna gel digitizing.

-- 
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!europa.eng.gtefsd.com!library.ucla.edu!agate!news.ucdavis.edu!pbmac-1.ucdavis.edu!user
From: jmbraverman@ucdavis.edu (John M. Braverman)
Newsgroups: bionet.software
Subject: SeqApp+Phylip
Message-ID: <jmbraverman-041193094033@pbmac-1.ucdavis.edu>
Date: 4 Nov 93 17:40:20 GMT
Sender: usenet@ucdavis.edu (News Administrator)
Followup-To: bionet.software
Organization: U.C. Davis
Lines: 7

Is anyone else having a problem running Phylip with SeqApp?  I have
followed the instructions exactly but can't get the Phylip objects to
appear under the Tasks.

-- 
John M. Braverman
U.C. Davis

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!daresbury!not-for-mail
From: jenkins@aidsun.nibsc.ac.uk
Newsgroups: bionet.software
Subject: G/C rich regions
Message-ID: <2bbbmn$c71@mserv1.dl.ac.uk>
Date: 4 Nov 93 16:47:19 GMT
Sender: daemon@mserv1.dl.ac.uk
Distribution: bionet
Lines: 10
To: bio-software@dl.ac.uk


Hello fellow netters

The PC package DNASIS has a utility to graphically display the G/C content of a sequence.  Does anybody know of a unix program/utility which will do the same??  If the program/utility is part of a PCR/sequencing primer designing package, all the better.

yours ever wonderingly....

Adrian Jenkins

Jenkins@uk.ac.nibsc.comp

From owner-software@net.bio.net Wed Nov 03 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!usc!howland.reston.ans.net!ee.und.ac.za!hippo.ru.ac.za!caesar.wits.ac.za!Witsvma.wits.ac.za!030NEILV
From: 030NEILV@Witsvma.wits.ac.za (Neil van der Merwe)
Newsgroups: bionet.software
Subject: Suggestions
Message-ID: <16C7C920F.030NEILV@Witsvma.wits.ac.za>
Date: 4 Nov 93 12:14:56 GMT
Organization: Wits University
Lines: 8
NNTP-Posting-Host: witsvma.wits.ac.za

Hi,
We are very soon to have our LAN linked up to the rest of the world
and are looking for suggestions of good news-reader and telnet (?)
(eg Clarksons telnet??) software for Microsoft Windows 3.1.  Any
useful tips will be much appreciated, as well as where this software
can be obtained.
Thanks in advance
Neil

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!spool.mu.edu!howland.reston.ans.net!pipex!uknet!mcsun!julienas!genethon!pat
From: pat@genethon.fr (Patricia Rodriguez-Tome)
Newsgroups: bionet.software
Subject: catalog of Moleuclar Biology Programs
Message-ID: <1993Nov5.165853@genethon.fr>
Date: 5 Nov 93 15:58:53 GMT
Sender: news@genethon.fr
Organization: Genethon -- Human Genome Research Centre
Lines: 297
Originator: pat@fourmi.genethon.fr
Nntp-Posting-Host: fourmi.genethon.fr


(the english version is at line : 43)

	Le CEPH-Fondation Jean Dausset et Genethon, avec le soutien du projet
	ReSIG (Reseaux de Serveurs Informatiques pour les Genomes) mettent en
	place un catalogue des logiciels d'interet general dans le champ de la
	biologie et de la genetique moleculaire. 

	Ce catalogue devrait contenir, a terme, la majorite des programmes
	existants (academiques, serveurs de traitement, commerciaux).
	L'accent est mis plus particulierement sur les environnments
	multi-utilisateurs orientes reseaux (eg. UNIX, VAX/VMS,
	IBM370/VM).  Ce catalogue ne peut etre maintenu a jour qu'avec
	l'aide de la communaute :  auteurs des programmes,
	administrateurs des archives et utilisateurs.  Nous serions
	heureux de recevoir vos corrections, commentaires et annonces
	de nouveaux logiciels aux adresses suivantes :

	- Patricia.Rodriguez-Tome@genethon.fr
	- Dominique.Caterina@genethon.fr

	Dans un premier temps les domaines retenus sont les suivants :

	- l'analyse de sequence (version 1.0)
	- la phylogenie (version 1.0)
	- l'analyse de liaisons genetiques (version 2.0)
	- l'acquisition des donnees experimentales, en particulier traitements
	d'images. (version 3.0)

	D'autres domaines seront pris en compte ulterieurement, mais
	ou s'arrete la biologie moleculaire?

	Le catalogue des bases de donnees disponibles est maintenu par
	Amos Bairoch (bairoch@cmu.unige.ch) sur expasy.unige.ch .

	Merci a tous pour votre cooperation
	et Enjoy it!

	Patricia Rodriguez-Tome
	CEPH - GENETHON 
	Patricia.Rodriguez-Tome@genethon.fr

=========================================================================
(english)

With the support of the RESIG project (Networks of computer servers for
Genomes),  the CEPH-Fondation-Jean-Dausset and Genethon have been
collecting a software  directory of general interest in molecular
biology and genetics.  In the long run, such a directory ought to
contain most of the existing programmes (from  academic, processing
servers to commercial programmes), with some emphasis on
network-oriented multi-user environments (eg UNIX, VAX/VMS).

This directory cannot  be up-to-date without the help of the computer
community, that is to say the programme  authors, archive
adminsitrators and end-users.

Thus, any corrections, comments and announcements of new software would
be mostly welcome at the following addresses :

 - Patricia.Rodriguez-Tome@genethon.fr 
 - Dominique.Caterina@genethon.fr

At first, the areas taken into account are as follows :
	 - sequence analysis (release 1.0) 
         - phylogeny (release 1.0) 
         - linkage analysis (release 2.0) 
         - experimental data acquisition, 
           specially image processing (release 3.0)


Subsequently, other areas will be taken into account, but where does
molecular biology  stop ? 

The directory of available databases is maintained by Amos Bairoch
(bairoch@cmu.unige.ch) on expasy.unige.ch 

Thank you very much for your cooperation and Enjoy it !
	Patricia Rodriguez-Tome
	CEPH - GENETHON 
	Patricia.Rodriguez-Tome@genethon.fr

 -----------------------------------------------------------------------------

	USAGE :


	Cette premiere version, encore experimentale et incomplete est
	disponible sur le serveur de genethon avec les procedures
	suivantes :
        The first release, which is still experimental and uncomplete, is
        available on genethon's  server with the following procedures :
		
	ftp anonyme sur ftp.genethon.fr pub/resig/catalogue/bio-catal.1.0
					pub/resig/catalogue/bio-catal.1.0.resume

					=========
	gopher a (at) gopher.genethon.fr :
		1. About Genethon's Gopher
		2. Biblio/
	  -->	3. Bio Catalog/
			1. Bio Catalog (Thanks)
			2. Bio Catalog release 1.0 (resume)
			3. Bio Catalog release 1.0
			4. Bio Catalog release 1.0 <?>

					===========
	WAIS : le texte a ete indexe, et la source est :
		the text is indexed, and the source is :
	(:source
	:version 3
        :ip-name "wais-server.genethon.fr"
        :tcp-port 210
        :database-name "bio-catal"
        :cost 0.00
	:cost-unit :free
        :maintainer "Patricia.Rodriguez-Tome@genethon.fr"
        :description "Server created with Wais release 8 b5 (BIO) on Nov 2 1993
         The files of type para used in the index were:
         /gopher-data/bio_catal/bio-catal.1.0
         This is the indexed version of CEPH-GENETHON catalogue
	 for Molecular Biology programs.
         "  
         )

					=============
	World Wide Web : (tres bientot - very soon)

	URL: http://www.genethon.fr:80/genethon_fr.html   (en francais)
        URL: http://www.genethon.fr:80/genethon_en.html   (in english)

					=============
				

	REMERCIEMENTS:

	La premiere edition de ce catalogue a ete realisee par compilation des
	multiples documents disponibles sur l'Internet, completes par
	des communications personnelles d'experts du domaine.
	Nous tenons a remercier tous ceux qui, meme involontairement, nous
	ont prete leur concours.

	Toute erreur dans ce catalogue est notre faute, non la leur.

	ACKNOWLEDGEMENTS :

	The first edition of this directory comes from the compilation
	of various documents available on Internet and has been
	completed by personal communications from experts of each
	field.
	We would like to thank all the people who have cooperated, even
	unintentionally.


Lists :
------
NAME    List of molecular biology email servers
AUTHOR  Amos Bairoch / Dept. Medical Biochemistry / University of Geneva
ADDRESS Dept. Medical Biochemistry / University of Geneva, Switzerland
ADDRESS bairoch@cmu.unige.ch

NAME    List of molecular biology FTP servers for databases and software
AUTHOR  Amos Bairoch 
ADDRESS Dept. Medical Biochemistry / University of Geneva, Switzerland
ADDRESS bairoch@cmu.unige.ch

NAME    Catalogue des programmes 
AUTHOR  Philippe Dessen
ADDRESS Service de BioInformatique/ CNRS INSERM, France
ADDRESS dessen@gnome.inserm-vjf.fr

NAME	BIRCH
AUTHOR  
ADDRESS University of Manitoba, Canada

NAME    UNIX Molecular Biology Software on EMBL File Server
AUTHOR
ADDRESS EMBL, Germany
ADDRESS nethelp@embl-heidelberg.de

NAME    VMS Molecular Biology Software on EMBL File Server
AUTHOR 
ADDRESS EMBL, Germany
ADDRESS nethelp@embl-heidelberg.de

NAME    GENBANK SOFTWARE CLEARINGHOUSE
AUTHOR  Dave Kristofferson
ADDRESS Intelligenetics, Inc. USA
ADDRESS kristoff@net.bio.net

NAME    References for DNA seq.....
NAME    (article in the News)
AUTHOR  Sanjay Nayar <snayar@NEXT3.CS.UMR.EDU>
ADDRESS USA

NAME    Reviews of Seq Analysis Progs
NAME	(article in bionet.software)
AUTHOR  Harry Mangalam 
ADDRESS Dept of Biocomputing / The Salk Institute , USA
ADDRESS mangalam@salk-sgi.sdsc.edu

NAME    List of phylogenie programs
AUTHOR  Joe Felsenstein
ADDRESS Dept. of Genetics, Univ. of Washington, USA
ADDRESS joe@genetics.washington.edu 




FTP sites :
----------
ORGANISM : European biology Molecular Laboratory
NAME     : EMBL Anonymous Ftp Server
ADDRESS  : ftp.embl-heidelberg.de (192.54.41.33)
ADDRESS  : Germany

ORGANISM : Indiana University / Biology Department
NAME     : IuBio archive for biology
ADDRESS  : ftp.bio.indiana.edu (129.79.224.25)
ADDRESS  : USA

ORGANISM : University of Houston
NAME     : University of Houston Gene-Server
ADDRESS  : ftp.bchs.uh.edu (129.7.2.43)
ADDRESS  : USA

ORGANISM : National Institute of Genetics (NIG) (Japan)
NAME     : National Institute of Genetics ftp server
ADDRESS  : ftp.nig.ac.jp (133.39.16.66)
ADDRESS  : Japan

ORGANISM : National Center for Biotechnology Information (NCBI)
ADDRESS  : ncbi.nlm.nih.gov (130.14.20.1)
ADDRESS  : USA

ORGANISM : Dept. of Genetics, Univ. of Washington
ADDRESS  : evolution.genetics.washington.edu (128.95.12.41)
ADDRESS  : USA

ORGANISM :
ADDRESS  : anthro.utah.edu (128.110.192.93)
ADDRESS  : USA

ORGANISM :
ADDRESS  :  ftp.cs.utoronto.ca (128.100.3.6 or 128.100.1.105)
ADDRESS  : Canada

ORGANISM : University of Manitoba
ADDRESS  : ccu.umanitoba.ca (130.179.16.8)
ADDRESS  : Canada

ORGANISM : University of Geneva Switzerland
ADDRESS  : expasy.hcuge.ch (129.195.254.61)
ADDRESS  : Switzerland

ORGANISM : New Mexico State University
ADDRESS  : haywire.nmsu.edu (128.123.001.032)
ADDRESS  : USA

ORGANISM : NCI/FCRDC
ADDRESS  : ncifcrf.gov (129.43.2.10)
ADDRESS  : USA

ORGANISM : University of Virginia
ADDRESS  : uvaarpa.virginia.edu (128.143.2.7)
ADDRESS  : USA

ORGANISM : Department of Molecular biology / Massachussetts General Hospital
ADDRESS  : frodo.mgh.harvard.edu (132.183.190.10)
ADDRESS  : USA

ORGANISM : Department of Mathematics / Stanford University
ADDRESS  : gnomic.stanford.edu (36.120.0.19)
ADDRESS  : USA

ORGANISM : Molecular Biology Computer Research Resource (MBCRR)
ADDRESS  : mbcrr.harvard.edu (134.174.51.4)
ADDRESS  : USA

ORGANISM : New England BioLabs (NEB)
ADDRESS  : vent.neb.com (192.138.220.2)
ADDRESS  : USA

ORGANISM : Intelligenetics Inc.
ADDRESS  : net.bio.net (134.172.2.69)
ADDRESS  : USA

ORGANISM :
ADDRESS  : groucho.cs.psu.edu (130.203.2.12)
ADDRESS  : USA


-- 
-------------------------------------------------------------
Patricia RODRIGUEZ-TOME       Genethon
Internet : pat@genethon.fr
-------------------------------------------------------------

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!yeshua.marcam.com!zip.eecs.umich.edu!destroyer!news.itd.umich.edu!geneva.csmil.umich.edu!cash
From: cash@geneva.csmil.umich.edu (Howard Cash)
Newsgroups: bionet.software
Subject: Re: Software manipulation of ABI 373a traces
Keywords: 373a ABI sequenceingn
Message-ID: <2be15b$oqe@terminator.rs.itd.umich.edu>
Date: 5 Nov 93 17:05:47 GMT
References: <1993Nov1.215442.25113@mnemosyne.cs.du.edu>
Organization: Cognitive Science and Machine Intelligence Lab, U. of MIichigan
Lines: 25
NNTP-Posting-Host: geneva.csmil.umich.edu

Clint,

I tried to email you directly, but could not reach your host.

Several programs allow you to work with ABI trace files.  The ones that come
to mind are

SeqEd (Macintosh, Applied Biosystems, Foster City, CA)
Inherit (Sun SPARC with Macintosh front end [Mac stand-alone version is in
         the works], also Applied Biosystems)
SeqMan/LaserGene (Macintosh and, I think, PC versions, DNAStar, Madison, WI)
Sequencher (Macintosh, Gene Codes Corp., Ann Arbor, MI)
Generation (Sun SPARC, IntelliGenetics/Betagen, Inc., Mountain View, CA)
XDAP and its revisions (SUN workstations, by Roger Staden, MRC, England)

I am biased, so my opinion must be suspect, but there has been discussion
of these programs in this newsgroup and in the recent literature.  I have
phone numbers for most, if not all of the companies, so drop me a note if
you want more information.

Good luck,

Hobie Cash
cash@csmil.umich.edu
313-769-7249            

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!rc1!is1e!rlippens
From: rlippens@vub.ac.be (Lippens Renee)
Newsgroups: bionet.software
Subject: Reference Manager
Message-ID: <3391@rc1.vub.ac.be>
Date: 5 Nov 93 13:27:35 GMT
Sender: news@rc1.vub.ac.be
Organization: Brussels Free Universities (VUB/ULB), Belgium
Lines: 17
X-Newsreader: TIN [version 1.1 PL9]


  Our laboratory wants to purchase the bibliografic manager program
  named REFERENCE MANAGER (Windows version including the Capture module)
  at the best price.
  Anybody who has good addresses ...

  Thanks in advance
--
  +_______________________________________________________________+
  +                                                               +
  +  Lippens Renee               | Internet : rlippens@ulb.ac.be  +
  +  Computer Support Assistant                                   +
  +                                                               +
  +  Universite Libre de Bruxelles        | Fax   : 32 67 287777  +
  +  Departement de Biologie Moleculaire  | Phone : 32 67 287762  +  
  +  1400  Nivelles      Belgium          | CP 800                +
  +_______________________________________________________________+

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!spool.mu.edu!uwm.edu!rpi!utcsri!utnut!torn!nott!cunews!freenet.carleton.ca!Freenet.carleton.ca!aj429
From: aj429@Freenet.carleton.ca (Andrew St. Jean)
Newsgroups: bionet.software
Subject: MOTIF alignment program
Message-ID: <CG0wIq.E1y@freenet.carleton.ca>
Date: 5 Nov 93 14:35:14 GMT
Sender: news@freenet.carleton.ca
Organization: National Capital Freenet, Ottawa, Canada
Lines: 11


I have in my possession a paper by Hamilton Smith et al. (PNAS, vol. 87:826, 
1990) describing a program called MOTIF.  This program searches for conserved
patterns of amino acid residues in widely divergent proteins.  I would very 
much like to know where I might get this program.  I have already found a 
program called MOTIF on the EMBL ftp server.  The output from this pragram is
completely different from that described in the paper, though, so I don't think
it is the program I am looking for.  Any help would be greatly appeciated.
An
Andrew St. Jean
University of Ottawa

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!sol.ctr.columbia.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: Re: seqapp -- Mac sequence analysis
Message-ID: <CG0otH.41n@usenet.ucs.indiana.edu>
Date: 5 Nov 93 11:48:53 GMT
References: <2bdb6n$rbe@mserv1.dl.ac.uk>
Sender: news@usenet.ucs.indiana.edu (USENET News System)
Distribution: bionet
Organization: Biology, Indiana University - Bloomington
Lines: 84
Nntp-Posting-Host: sunflower.bio.indiana.edu


Regarding recent questions about how to get seqapp to work with
child tasks:  I don't have any answers at this time. There are bugs
in the program. I'm sorry that I don't have time a present to make
it completely bug-free, or to get it to work properly on all Mac systems.  
There will be a new release eventually, but not in the next few months.
In the mean time, send any bug reports to the address below. They
will help in curing problems for the next release.
							-- don

Here is a previous description for the curious:

SeqApp is a Macintosh biosequence editor, analyzer, and network 
handyman.  It includes links to network services and external analysis 
programs.

Features include	
	multiple sequence alignment editor
	single sequence editor window
	read and write several sequence file formats *
	easy hand alignment features including colored bases and sliding *
	automatic multiple sequence alignment thru Clustal external app 
	automatic gel fragment alignment to contigs thru CAP exernal app *
	consensus,reverse,complement,degap operations
	restriction maps
	dot plots
	translate dna to/from protein using various codon tables
	automatic preference saving *
	internet send mail, read mail
	internet gopher, information retreival including genbank.
	internet sequence analysis services
	user-definable links to external analysis programs
	and more
	
* These features were updated in release 1.9a.  See below for details.

NOTICE:  This program is not finished, and may fail in various ways.  Please 
send notice of any problems you have using it to the address below. This 
release will expire on a date indicated in the About dialog. 

SeqApp is being written by Don Gilbert, using the MacApp extensible Macintosh 
programming framework from Apple Computer.

You can obtain updates of this release thru anonymous ftp to  
ftp.bio.indiana.edu, in folder /molbio/seqapp, as seqapp.hqx.  You may also 
obtain updates directly thru an internet-connected Mac with SeqApp, using 
Gopher to the IUBio archive.  Look for a folder called "IUBio Software+Data/
SeqApp, Mac sequence editor".  There may be additional distribution software, 
data or information in this /molbio/seqapp folder.  See the Readme files in 
it for details. 

As of release 1.9a157, SeqApp fails once again to work on a Mac SE, or on any 
Mac running system software earlier than 7.0.  

Comments, bug reports and suggestions for new features may be sent by e-mail to

	     SeqApp@Bio.Indiana.Edu


History

SeqApp was started Sept. 1990 as MacApp sequence editor/analysis platform  on 
which analysis programs from other authors, typically command line w/ weak user 
interfaces, could be easily incorporated into a useable Mac interface.

12 June 93, version 1.9a159 -- a semi-major update, and time extension  
with various enhancements and corrections.  These include
  -- lock/unlock indels (alignment gaps). Useful when sliding bases around
     during hand alignment, to keep alignment fixed in some sections.
  -- color amino (and nucleic) acids of your choice.  
  -- added support for more sequence file formats: MSF, PAUP, PIR.  SeqApp now 
     relies on the current Readseq code for sequence reading & writing.
  -- save selection option to save subset of bases to file.
  -- addition the useful contig assembly program CAP, written by Xiaoqiu Huang.
  -- major revision of preference saving method (less buggy, I hope)
  -- major revision of the underlying application framework, due to moving from 
     MacApp 2 to MacApp 3.
  -- fixed a bug that caused loss of data when alignment with a selection was 
     saved to disk.



-- 
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!pipex!sunic!trane.uninett.no!news.eunet.no!nuug!news.eunet.fi!funic!nic.funet.fi!csc.fi!harper
From: Rob.Harper@csc.fi (Rob Harper)
Newsgroups: bionet.software
Subject: Yet another gopher for Windows and Winsock
Message-ID: <199311050659.AA26091@csc.fi>
Date: 5 Nov 93 06:59:52 GMT
Sender: root@nic.funet.fi (The FUnny NET guru)
Organization: Finnish Academic and Research Network Project - FUNET
Lines: 165



>Path: funic!news.funet.fi!sunic!pipex!howland.reston.ans.net!spool.mu.edu!umn.edu!news2.cis.umn.edu!gopher-news-daemon@boombox.micro.umn.edu
>Date: Thu, 4 Nov 1993 16:57:19 -0700
>From: dob@tis.inel.gov (Dave Brooks)
>Message-ID: <9311042357.AA18523@dewey.inel.gov>
>Original-To: Brewster@wais.com, gopher-news@boombox.micro.umn.edu,
>        winsock@sunsite.unc.edu, Lois.Schoen@Forsythe.Stanford.EDU,
>        aaron@datatools.com, saint@wais.com, bjs@inel.gov, tis@inel.gov,
>        jason.levine@columbia.edu, jim@netmanage.com, rcq@ftp.com,
>        bruce@frontiertech.com, davidtr@microsoft.com, vikas@distinct.com,
>        PETER@psychnet.psychol.utas.edu.au, chrisl@ncms.org, martinh@jsbus.com,
>        amonson@amonson.ag.uidaho.edu, trier@odin.INS.CWRU.Edu,
>        howardd@ricks.edu, daniel@mudhoney
>Subject: Announcing (Yet Another) WinSock Gopher Client
>Newsgroups: comp.infosystems.gopher
>Distribution: comp
>Sender: news@news2.cis.umn.edu
>Approved: comp.infosystems.gopher@news.cis.umn.edu
>Lines: 145


[Note: I just uploaded this software to
boombox.micro.umn.edu:pub/gopher/incoming and microdyne.com:pub/incoming
... sunsite does not seem to be responding, but I'll keep trying]

                                  Announcing
                           A Windows Sockets Gopher
                                WinSock Gopher
                                 Version 0.9f
                               November 4, 1993

** Introduction

    WSGopher is a Gopher client for Microsoft Windows 3.1 and Windows
Sockets (or WinSock) version 1.1.  It was designed from the ground up to
take advantage of, and build up, Windows and WinSock.  In particular
WSGopher uses the parallel capabilities of WinSock to allow the user to
fetch as many items at once as they care to.  It also takes advantage of
Windows "associations", the Clipboard, printer, etc.

    WSGopher has many features which support ease of use, speed and
flexibility, including:

    - Data appears in a window AS IT ARRIVES on your computer; you don't
have to wait for something to be completely transferred.  There is no
hourglass cursor in WSGopher.

    - As soon as data appears on your screen, you can start using it.  This
means you can select items from a directory window while the directory is
still downloading.  I do this all the time with the "All the Gopher Servers
in the World" directory.

    You can also scroll through your text window, and even mark text and
copy it to the clipboard, print it or save it to disk while the text file is
downloading.

    - You can easily do more than one thing at a time; in fact, you can do
as many things as you want, until you run out of resources (like using up
all your network sockets).  I often have four to six file downloads going on
at once, or a similar number of directories and text documents.  The only
limitation is my attention span.

    - WSGopher uses the Windows MDI feature, giving you multiple document
windows within a single containing window.  WSGopher windows are highly
customized to the document type.

    - WSGopher has built in viewers for text and CSO types.  The text viewer
can display up to 32K lines (unlimited in future versions).  You can also
configure the font for the text viewer.  The CSO viewer supports the
"fields" feature by downloading the fields from the CSO server into a "drop
list", which can then be used while forming queries.  You can perform
multiple queries on a CSO server.

    - WSGopher uses File Manager associations for external document viewing,
so if your PC can view PostScript, so can WSGopher.  However you can still
customize or override viewers within WSGopher.

    - There are many, many other features.  Please consult the file
"features.txt" which is included in the distribution.

** Important legal info

Copyright (C) 1993 EG&G Idaho, Inc.
"All Rights Reserved"
Idaho National Engineering Laboratory, Idaho Falls, Idaho, USA

DISCLAIMER

This program was prepared as an account of work sponsored by an agency of the
United States Government.  Neither the United States Government nor any agency
thereof, nor any of their employees or contractors, makes any warranty,
express or implied, or assumes any legal liability of responsibility for the
accuracy, completeness, or usefulness of any information, apparatus, product
or process disclosed, or represents that its use would not infringe privately
owned rights.

PERMISSION TO USE, COPY, AND DISTRIBUTE THIS SOFTWARE AND ITS DOCUMENTATION
FOR ANY NON-COMMERCIAL PURPOSE, WITHOUT FEE, IS HEREBY GRANTED, PROVIDED THAT
THE ABOVE COPYRIGHT NOTICE AND THIS PERMISSION NOTICE APPEAR IN ALL COPIES OF
THE SOFTWARE AND SUPPORTING DOCUMENTATION, AND THAT ALL EG&G IDAHO, INC.
IDENTIFICATION IN THE USER INTERFACE REMAIN UNCHANGED.  NO INTEREST IN OR TITLE
TO THIS SOFTWARE IS GRANTED HEREIN.


** What this distribution includes

    The file "wsg-09f.exe" is a self extracting archive.  I've found that not
everyone has the latest and greatest version of popular archiving tools, so
I've chosen this method as the one that provides the least hassle to the
greatest number of users.

   The files in the archive include:

        wsgopher.exe                      the executable
        wsgopher.ini                      the "resource" file
            Important note:  this file does NOT have to be copied to
             the WINDOWS directory.  It can safely reside in the same
            directory as the executable; but you can move it to the
            WINDOWS directory if you wish.
        wsgopher.hlp                      Incomplete, not very useful (yet)
        announce.txt                      this file
        install.txt                       installation instructions
        features.txt                      A quick list of WSGopher features
        powerusr.txt                      A guide for power users

** Availability

    WSGopher is (or will be) available via anonymous FTP on the following
hosts:

boombox.micro.umn.edu              pub/gopher/Windows
sunsite.unc.edu                    pub/micro/pc-stuff/windows/winsock/apps

I've placed it to the appropriate upload directories, so hopefully it will
show up soon in the directories indicated.

    Look for the file "wsg-09f.exe" and be sure to transfer it with binary
mode.

** Installation

The file 'install.txt' contains installation instructions.  However,
since the file is included in the archive, I've included few
paragraphs here to help you get started:

    Decide where on your disk you plan to install WSGopher.  Let's say,
    for the sake of discussion, that you make a directory c:\wsgopher and
    decide to put the software there. 

    The file 'wsg-09f.exe' is a self extracting archive that contains the
    WSGopher executable, INI file and several documentation files.  Change
    directory to c:\wsgopher, and execute the wsg-09f program.  After
    this, you will not need the wsg-09f program any longer.

[ end of excerpt ]

You are invited to read the entire file.  It is short, because there's
not much you need to know to make WSGopher work for you.

** Known bugs

Known bugs are listed at the end of 'features.txt'.

Dave Brooks

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!munnari.oz.au!metro!usage!news
From: Shaharin Yussof
Newsgroups: bionet.software
Subject: Re: Trumpet and winsoc
Message-ID: <1993Nov5.005248.28440@usage.csd.unsw.OZ.AU>
Date: 5 Nov 93 00:52:48 GMT
Sender: news@usage.csd.unsw.OZ.AU
Organization: Department of Safety Science, USNW
Lines: 13
Nntp-Posting-Host: 149.171.28.200
X-Newsreader: <WinQVT/Net v3.9>

In article <16C7CDC3A.030NEILV@Witsvma.wits.ac.za> 030NEILV@Witsvma.wits.ac.za (Neil van der Merwe) writes:
>Hi,
>Can anyone tell me where I can get hold of Trumpet and Winsoc?  I also
>need some info on winsoc, as I am totally unfamiliar with it.
>Thanks in advance,
>Neil

Try anonymous ftp to biochemistry.cwru.edu

You might also try the shareware QVTNET as a TCP/IP, mail, newsreader, and FTP 
program.  It is available in the same place.

Shaharin 

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!PCLSP2.KUICR.KYOTO-U.AC.JP!vinz
From: vinz@PCLSP2.KUICR.KYOTO-U.AC.JP (Vinz-san)
Newsgroups: bionet.software
Subject: SeqApp problem
Message-ID: <9311050809.AA12234@pclsp2>
Date: 5 Nov 93 08:09:27 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 23


I have just read the letter of John M. Braverman that states the following:
>Is anyone else having a problem running Phylip with SeqApp?  I >have
>followed the instructions exactly but can't get the Phylip objects to
>appear under the Tasks.

Also in my case I can not launch Phylip. Moreover I can not launch any
child task as ClustalV, and if I try the computer shows a Disk Reading
Error. I have tried to retrieve several times the program from the 
gopher, but it does not seem to be a retrivial error.
Can anyone suggest me how to implement SeqApp in order to run it
properly?

Thank you very much indeed

Vincenzo nardi-Dei

Kyoto University


vinz@pclsp2.kuicr.kyoto-u.ac.jp



From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!pipex!howland.reston.ans.net!usc!yeshua.marcam.com!zip.eecs.umich.edu!destroyer!news.itd.umich.edu!spencer
From: spencer@med.umich.edu (Spencer W. Thomas)
Newsgroups: bionet.software
Subject: Re: <Q> Saving list of hits with Gopher
Message-ID: <SPENCER.93Nov5105734@guraldi.med.umich.edu>
Date: 5 Nov 93 18:57:34 GMT
References: <hill.1102816919A@netnews.nyu.edu>
Organization: University of Michigan HSITN
Lines: 14
NNTP-Posting-Host: guraldi.itn.med.umich.edu
In-reply-to: hill@mcclb0.med.nyu.edu's message of Thu, 4 Nov 93 16:07:59 GMT

In article <hill.1102816919A@netnews.nyu.edu> hill@mcclb0.med.nyu.edu (John Edward Hill) writes:
> After doing a TurboGopher (Macintosh) search on GenBank (or other
> databases), is there a way to save the list of hits as a text file?

Try MacMosaic.  The current version is
ftp.ncsa.uiuc.edu:/Mac/Mosaic/NCSAMosaicMac.B6.sit.Hqx

You can save any "page" as a text file.  You also get access to the
whole WWW (World Wide Web), which includes gopher as a subset.

--
=Spencer W. Thomas 		|  Info Tech and Networking, B1911 CFOB, 0704
   "Genome Informatician"	|  Univ of Michigan, Ann Arbor, MI 48109
Spencer.W.Thomas@med.umich.edu	|  313-764-8065, FAX 313-764-4133

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!pipex!uknet!nessie!nessie.mcc.ac.uk!sr
From: sr@zen.mp.co.umist.ac.uk (Simon Read)
Newsgroups: bionet.software
Subject: Quanta and SGIs
Message-ID: <SR.93Nov5145314@zen.mp.co.umist.ac.uk>
Date: 5 Nov 93 14:53:14 GMT
Sender: news@nessie.mcc.ac.uk (Usenet News System)
Organization: Umist/Manchester Computing Centre Sun 630MP
Lines: 14

A friend of mine over in Pharmacy is having problems getting picture
files of molecules modelled in this package. The function in the
package itself seems to be broken.

Does any one have any suggestions about fixing the function?

Does anyone know how we could get just a screen dump from and SGI (or
for that matter an Indigo)?

Thanks in advance

Simon Read
----------
Simon.Read@umist.ac.uk

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!uunet!nih-csl!helix.nih.gov!chuck
From: chuck@helix.nih.gov (Chuck Buckler)
Newsgroups: bionet.software
Subject: Re: Trumpet and winsoc
Message-ID: <1993Nov5.095110@helix.nih.gov>
Date: 5 Nov 93 14:51:10 GMT
References: <16C7CDC3A.030NEILV@Witsvma.wits.ac.za>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Reply-To: chuck@helix.nih.gov (Chuck Buckler)
Organization: National Institutes of Health
Lines: 22

In article <16C7CDC3A.030NEILV@Witsvma.wits.ac.za>,
030NEILV@Witsvma.wits.ac.za (Neil van der Merwe) writes:
|> Hi,
|> Can anyone tell me where I can get hold of Trumpet and Winsoc?  I
also
|> need some info on winsoc, as I am totally unfamiliar with it.
|> Thanks in advance,
|> Neil

--
follow what's happening in alt.winsock and comp.protocols.tcp-ip.ibmpc

+-=-=-=-=-=-=-=-=-=-=-=-=-=-=-+-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
-=-+
| Chuck Buckler               |   internet - chuck@mizzen.niaid.nih.gov 
|
| Build. 4, Rm. 301, NIH      |   NIAID-LAN MBUG                        
|
| Bethesda, MD 20892, USA     |   301-496-1498       FAX - 301-402-0226 
|
+-=-=-=-=-=-=-=-=-=-=-=-=-=-=-+-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
-=-+

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!pipex!uunet!utcsri!utnut!torn!nott!cunews!freenet.carleton.ca!Freenet.carleton.ca!aj429
From: aj429@Freenet.carleton.ca (Andrew St. Jean)
Newsgroups: bionet.software
Subject: Looking for a protein analysis program
Message-ID: <CG0wxL.EBG@freenet.carleton.ca>
Date: 5 Nov 93 14:44:08 GMT
Sender: news@freenet.carleton.ca
Organization: National Capital Freenet, Ottawa, Canada
Lines: 9


I looking for a program that will predict a protein`s secondary
structure from its sequence and then allow me to compare the
secondary structures of a number of proteins.  The program must
be able to run either under UNIX or DOS/Windows.  Any help in this
matter would be greatly appreciated.

Andrew St. Jean
University of Ottawa

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!VAX86.LIUNET.EDU!SHODELL
From: SHODELL@VAX86.LIUNET.EDU
Newsgroups: bionet.software
Subject: molecular graphics query
Message-ID: <9311051824.AA27305@net.bio.net>
Date: 5 Nov 93 17:20:00 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 4

I am seeking any programs -- commercial or public -- which can be
recommended for early college use in bio courses for demonstrating
molecular bonding, macromolecular structure and molecular interactions.
Please respond to:  IN%"shodell@vax86.liunet.edu"   Many thanks.

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!AUDREY.LMF.ORG!jim
From: jim@AUDREY.LMF.ORG (Jim Gale)
Newsgroups: bionet.software
Subject: Windows telnet and ftp software
Message-ID: <9311051920.AA19760@audrey.lmf.org>
Date: 5 Nov 93 19:20:39 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 8


I am a Windows PC user. However I cuurently use a dos Kermit to do Telnet
and a dos FTP. Are there any good WINDOWS software to do telnet and FTP??
What are you using??? I had heard that early windows software for this
purpose used a large amount of needed conventional memory (as a TSR), is this
true now??
Thanks in advance
Jim

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!nih-csl!postman
From: dspete@helix.nih.gov
Newsgroups: bionet.software
Subject: Re: Windows telnet and ftp software
Message-ID: <1993Nov5.225654.17587@alw.nih.gov>
Date: 6 Nov 93 01:54:34 GMT
References: <9311051920.AA19760@audrey.lmf.org>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Organization: National Institutes of Health
Lines: 22
Content-Type: TEXT/PLAIN; charset=US-ASCII
Mime-Version: 1.0


In article <9311051920.AA19760@audrey.lmf.org>, <jim@AUDREY.LMF.ORG> writes:
 
> I am a Windows PC user. However I cuurently use a dos Kermit to do Telnet
> and a dos FTP. Are there any good WINDOWS software to do telnet and FTP??
> What are you using??? I had heard that early windows software for this
> purpose used a large amount of needed conventional memory (as a TSR), is this
> true now??
> Thanks in advance
> Jim

Jim,

I've been using Chameleon TCP/IP from NetManage for several months now and find 
it to be a very slick package. The memory requirements are small (approx 20K) 
since it is a true Windows implementation, not a kludge built upon dos TSRs. 
The package does telnet, FTP, has a news reader, and a POP3 mail client. 
Overall very nice. The one drawback is price, about $400 for the package. It 
also includes a WinSock interface that works great with the Gopher+ client I've 
got running.

David 

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!sdd.hp.com!spool.mu.edu!howland.reston.ans.net!vixen.cso.uiuc.edu!news.cso.uiuc.edu!fenton
From: fenton@nemo.life.uiuc.edu (Jim Fenton)
Newsgroups: bionet.software
Subject: Re: Trumpet and winsoc
Message-ID: <fenton.752530902@news.cso.uiuc.edu>
Date: 5 Nov 93 20:21:42 GMT
References: <1993Nov5.005248.28440@usage.csd.unsw.OZ.AU>
Organization: University of Illinois at Urbana
Lines: 25
NNTP-Posting-Host: nemo.life.uiuc.edu

Shaharin Yussof writes:

>In article <16C7CDC3A.030NEILV@Witsvma.wits.ac.za> 030NEILV@Witsvma.wits.ac.za (Neil van der Merwe) writes:
>>Hi,
>>Can anyone tell me where I can get hold of Trumpet and Winsoc?  I also
>>need some info on winsoc, as I am totally unfamiliar with it.
>>Thanks in advance,
>>Neil

>Try anonymous ftp to biochemistry.cwru.edu

>You might also try the shareware QVTNET as a TCP/IP, mail, newsreader, and FTP 
>program.  It is available in the same place.

>Shaharin 

Is it just me or did QVTNET work for others.  I never got the lpr print stuff
to work properly, the windows version was amazingly slow and wouldn't
work with our NFS network (yes, we have a weird mix of unix and pc's that
adds some difficulties).  I'm much more happy since I turned our PC's running
windows into X terminals with eXceed/W for windows.  Of course, this isn't
shareware, but it wouldn't surprise me to find that there are public domain
versions of X emulators available.
-- 
  Jim Fenton	 fenton@nemo.life.uiuc.edu  

From owner-software@net.bio.net Thu Nov 04 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!xlink.net!scsing.switch.ch!swidir.switch.ch!news.unige.ch!cmu.unige.ch!dlowry
From: dlowry@cmu.unige.ch (Dorothy Lowry)
Newsgroups: bionet.software
Subject: Re: Trumpet and winsoc
Message-ID: <dlowry.20.2CDA46E1@cmu.unige.ch>
Date: 5 Nov 93 12:28:17 GMT
References: <1993Nov5.005248.28440@usage.csd.unsw.OZ.AU>
Sender: usenet@news.unige.ch
Organization: University of Geneva
Lines: 136
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

In article <1993Nov5.005248.28440@usage.csd.unsw.OZ.AU> Shaharin Yussof writes:

>In article <16C7CDC3A.030NEILV@Witsvma.wits.ac.za> 030NEILV@Witsvma.wits.ac.za
>(Neil van der Merwe) writes:
>>Hi,
>>Can anyone tell me where I can get hold of Trumpet and Winsoc?  I also
>>need some info on winsoc, as I am totally unfamiliar with it.
>>Thanks in advance,
>>Neil

>Try anonymous ftp to biochemistry.cwru.edu

>You might also try the shareware QVTNET as a TCP/IP, mail, newsreader, and FTP 
>program.  It is available in the same place.

>Shaharin 


I have just installed Trumpet and Winsock and all the other super software that
needs Winsock (including Winmosaic).  I cannot tell you how much I like 
Trumpet, in fact, I am writing this using Trumpet at this very minute.  

Anyway, here is a brief tutorial on Winsock, etc, hopefully it will save 
somebody a little time:

Winsock is a set of routines that link dynamically to various programs 
that can use Winsock.  Trumpet Winsock is one of a number of 
Winsocks, however, I believe it is the only one that is a shareware version, 
and it is certainly the one that is most widely used among the people I know...

NOTE 1:  If you are using FTP Software Inc, PC/TCP, you need FTP Software's
version of Winsock...this is downloadable from many anonymous FTP sites.

The good news:  Your  program will detect your Winsock, and auto-magically 
run ... IF YOU SET UP THE WINSOCK PROPERLY ... although, of course
various programs such as Trumpet and WinQVT need to know various parameters
about your network, so you will need to READ THE DOCUMENTATION that comes
with each of these programs before you install them.

You should know that the following "layers" are required:

         [ Program that uses Winsock:                                        
         [ runs under Win 3.1 - example Trumpet News Reader 

         "on top of"
         [ Winsock 

         " on top of "
         [ a program that creates "virtual" packet drivers for Winsock
         [ that lets you multitask your Winsock applications               
         [   example:  winpkt.com or pktmux                                  

         "on top of"
         [ a Crynwyr packet driver (used to be called Clarkson drivers).


The purpose of the packet driver is to talk to your ethernet card and
direct any packets that arrive at your computer addressed to it, to
the program that they should go to. 

Note 2:  Each packet driver is written SPECIFICALLY for each
Ethernet card.  You must have the packet driver that is written
for that card that is in your computer.  In fact, if you are 
connected to the network, you probably already have the
one that you need! Look in your network.bat or autoexec.bat
file (hopefully you will have such a thing) for more information.
With luck, you will be able to match up the name of your
packet driver with one of the Crynwyr drivers...if not follow the
documentation that comes with the Crynwyr drivers in order
to install it.
      
Run the packet driver, THEN run the virtual packet driver
addressing program.  I THINK that the only card that is known
not to work with winpkt.com, is the BICC 16 bit card (4110 - 2/3)
Guess which card is in MY computer ??? :-) if you have this
card then you need to run pktmux then pktdrv.  See the pktmux
documentation for more details...

winpkt.com is called like this:   winpkt 0x[vv] 0x[nn]

     where [vv] is the address that you choose to put 
                       the virtual packet driver at.
                [nn] is the actual address that the packet
                       driver is located at.

The 0x part says that it is in HEX - I think that most packet
driver addresses are already in hex - but check the Crynwyr
documentation for your packet driver.

Now you are ready to start your trumpet winsock.  I assume
you have unzipped it and put it in whatever directory, plus
made an icon for it in Windows.  Before you start Windows
make sure that you have the following information:

the ip address of your computer
the ip address of your default gateway
the ip address of your nameserver, timeserver
your domain name

I got all this information out of my existing setup...you may 
need some help with this from the network administration-
type people.

Click on the Trumpet Winsock icon and fill in the network 
setup information. THE ADDRESS THAT YOU GIVE,
WILL BE THE VIRTUAL ADDRESS THAT YOU TOLD 
WINPKT.COM to use.

Now, restart Trumpet winsock and use some of the programs
that come with it to see if it is working...try using PING and
ping at the ip address of a computer near you, your nameserver,
etc.  Then try to ping on a name...if all goes well, you are 
ready to start installing the rest of your software that uses
Winsock.

If you see an ARP Timeout error in the debug screen, it may
mean you have the same kind of ethernet card that I have and
you will have to use pktmux and pktdrv instead of winpkt.com

Make sure that the winpkt.com that you get is up to date!  Get
the latest version that you can find.
                
Happy winsocking !!!!
-- Dorothy Lowry

PS:  you WILL need to read the documentation...           


============================================================
Dorothy Lowry		      E-mail: dlowry@cmu.unige.ch
Graduate Student  &           phone:  +41-22-702-5490
PC/GENE Programmer            Fax:    +41-22-346-8758

Dept. Medical Biochemistry, University of Geneva
CMU, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland
============================================================

From owner-software@net.bio.net Fri Nov 05 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!spool.mu.edu!sgiblab!barrnet.net!noc.usfca.edu!Dr.Chihara
From: Chihara@alm.admin.usfca.edu (Dr. Chihara)
Newsgroups: bionet.software
Subject: Looking for restriction mapping program
Message-ID: <2beoes$3fi@noc.usfca.edu>
Date: 5 Nov 93 23:43:24 GMT
Sender: -Not-Authenticated-[5160]
Organization: USF
Lines: 8
NNTP-Posting-Host: 138.202.6.144
X-Posted-From: InterNews 1.0@noc.usfca.edu.
Xdisclaimer: No attempt was made to authenticate the sender's name.

Does anyone know of a simple restriction mapping program I could use in
upper division courses in genetics to give students help in making
linear and circular maps?

Dr. Chihara
Chihara@usfca.edu
USF
__________________________________

From owner-software@net.bio.net Fri Nov 05 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!mcsun!sun4nl!star.cs.vu.nl!balaena!mac_dw2_2.bio.vu.nl!user
From: deboer@bio.vu.nl (Thon de Boer)
Newsgroups: bionet.software
Subject: Re: Software manipulation of ABI 373a traces
Message-ID: <deboer-061193154650@mac_dw2_2.bio.vu.nl>
Date: 6 Nov 93 14:46:50 GMT
References: <1993Nov1.215442.25113@mnemosyne.cs.du.edu> <2be15b$oqe@terminator.rs.itd.umich.edu>
Sender: news@bio.vu.nl
Followup-To: bionet.software
Organization: Vrije Universiteit, Amsterdam
Lines: 31

In article <2be15b$oqe@terminator.rs.itd.umich.edu>,
cash@geneva.csmil.umich.edu (Howard Cash) wrote:

> Clint,
> 
> I tried to email you directly, but could not reach your host.
> 
> Several programs allow you to work with ABI trace files.  The ones that come
> to mind are
> 
> SeqEd (Macintosh, Applied Biosystems, Foster City, CA)
> Inherit (Sun SPARC with Macintosh front end [Mac stand-alone version is in
>          the works], also Applied Biosystems)
> SeqMan/LaserGene (Macintosh and, I think, PC versions, DNAStar, Madison, WI)
> Sequencher (Macintosh, Gene Codes Corp., Ann Arbor, MI)
> Generation (Sun SPARC, IntelliGenetics/Betagen, Inc., Mountain View, CA)
> XDAP and its revisions (SUN workstations, by Roger Staden, MRC, England)
> 
> I am biased, so my opinion must be suspect, but there has been discussion
> of these programs in this newsgroup and in the recent literature.  I have
> phone numbers for most, if not all of the companies, so drop me a note if
> you want more information.
> 

The new version of GeneJockey II (BioSoft) can also handle the ABI files in
a sequencing project or so I am told by their catalog. I have not tried it
yet for I am waiting on my demo disk (oohoo BioSoft, are you listening :-)
Maybe there is someone out there who could send me the Demo version of
GeneJockey or put it in a ftp site ?

Sincerely, Thon de Boer

From owner-software@net.bio.net Fri Nov 05 22:00:00 1993
Path: biosci!THEORY.BCHS.UH.EDU!dbd
From: dbd@THEORY.BCHS.UH.EDU (Dan Davison)
Newsgroups: bionet.software
Subject: PIR Release 38 available for FTP
Message-ID: <9311062211.AA17162@theory.BCHS.UH.EDU>
Date: 6 Nov 93 22:11:26 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 26

Courtesy of the National Biomedical Research Foundation staff, 
PIR Release 38 is available for anonymous FTP from ftp.bchs.uh.edu
129.7.2.43, in the directory

	~ftp/pub/gene-server/pir/pir_rel38/{ascii,vms}/...

I have checked the ASCII version and it appears to be OK; I no
longer have the disk space to check the VMS version.  Remember that
to use the VMS version with GCG 7.X you must run dbindex first!

The files are stored as compressed format, so you must transfer them
in FTP's "binary" mode, the use the Unix "uncompress" command.
There are decompress utilities for VMS: for example, see
~ftp/pub/gene-server/pir/decompress-vms.exe and the readme file.

The UH Gene-Server PIR Gopher (gopher to gopher.bchs.uh.edu) and PIR 
e-mail service (send the command SEND PIR HELP to gene-server@bchs.uh.edu)
are serving the new release.

If you have any question, please contact Dan Davison at davison@uh.edu.

dan davison
gene-server manager


	

From owner-software@net.bio.net Fri Nov 05 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!swrinde!emory!sol.ctr.columbia.edu!howland.reston.ans.net!ee.und.ac.za!csir.co.za!op1.up.ac.za!alang
From: alang@op1.up.ac.za (Alan Guthrie)
Newsgroups: bionet.software
Subject: Asyst Users
Message-ID: <alang.4.0@op1.up.ac.za>
Date: 6 Nov 93 17:25:02 GMT
Organization: Faculty of Veterinary Science, Onderstepoort
Lines: 15
NNTP-Posting-Host: 137.215.115.89
X-Disclaimer: None of the opions expressed herein are the official
X-Disclaimer: opinions of the CSIR or any of its subsidiaries.
X-Disclaimer: **  So don't freak out at _us_ about anything  **

We use Asyst 4.01 from Asyst Software Technologies (now Keithley 
Instruments) for data capture and analysis in our laboratory.  A number of 
other people are using Asyst locally and we are in the process of setting 
up an Asyst Users Group.  I have been asked to try to make contact with 
other Asyst users and/or Asyst Users Groups.  Please could anyone with 
information that could help me in this regard reply to this message.


Alan Guthrie
Director: Equine Research Centre
Faculty of Veterinary Science
University of Pretoria
Republic of South Africa

Internet: ALANG@OP1.UP.AC.ZA 

From owner-software@net.bio.net Fri Nov 05 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!agate!howland.reston.ans.net!gatech!news-feed-1.peachnet.edu!umn.edu!msus1.msus.edu!TIGGER.STCLOUD.MSUS.EDU!Q00001
From: q00001@TIGGER.STCLOUD.MSUS.EDU
Newsgroups: bionet.software
Subject: remote data acquisition from greenhouse modules
Message-ID: <1993Nov6.161226.6452@msus1.msus.edu>
Date: 6 Nov 93 22:12:26 GMT
Reply-To: q00001@TIGGER.STCLOUD.MSUS.EDU
Organization: ST. CLOUD STATE UNIVERSITY, ST. CLOUD, MN
Lines: 15
Nntp-Posting-Host: tigger.stcloud.msus.edu

I am the faculty supervisor of a small university greenhouse.  I have 
investigated data acquisition and logging of temperature/humidity from the 
six growing modules.  Those which are available from Johnson Control et. al.
are acquisition and control as well as quite expensive.  I can get a IBM/DOS
computer (286 or 386) from the computer center as they upgrade and dedicate
it to data logging.  Does anyone have any suggestions on what types of 
software and remote sensors might be available for this purpose. 
David DeGroote 
q00001@tigger.stcloud.msus.edu
snail mail:
Department of Biology
St. Cloud State University
St. Cloud, MN  56301-4498
USA
Thanks in advance for your time and experience.

From owner-software@net.bio.net Sat Nov 06 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!warwick!uknet!pipex!uunet!ulowell!woods.ulowell.edu!leylandr
From: leylandr@woods.ulowell.edu
Newsgroups: bionet.molbio.methds-reagnts,bionet.software,bionet.software.pc
Subject: DATABASE for Restriction Enzyme Buffers!
Message-ID: <1993Nov7.094217.1@woods.ulowell.edu>
Date: 7 Nov 93 14:42:17 GMT
Organization: University of Massachusetts Lowell
Lines: 13
Xref: biosci bionet.molbio.methds-reagnts:8880 bionet.software:6413
NNTP-Posting-Host: aspen.uml.edu

Our Massachusetts-based software development group is in need of feedback
regarding our development of a database which facilitates buffer selection
for use with commercially-available restriction enzymes.

Has anyone experience with similar databases, and if so, which improvements
would you suggest?



We're always interested in researchers' suggestions for new and innovative
laboratory software products, so drop us a line and outline your ideas!

If we develop your suggestion, your lab will receive a complimentary copy!

From owner-software@net.bio.net Sat Nov 06 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!swrinde!emory!europa.eng.gtefsd.com!library.ucla.edu!csulb.edu!csus.edu!netcom.com!vdvk
From: vdvk@netcom.com (Didier Vanderveken)
Newsgroups: sci.chem,comp.sys.mac.scitech,fj.sci.chem,bionet.software,sci.comp-aided,sci.techniques.xtallography
Subject: List of Molecular Graphic Packages
Message-ID: <vdvkCG3o58.4n8@netcom.com>
Date: 7 Nov 93 02:27:08 GMT
Organization: Catalytica
Lines: 73
Xref: biosci sci.chem:8435 comp.sys.mac.scitech:639 bionet.software:6412 sci.comp-aided:279 sci.techniques.xtallography:20
X-Newsreader: TIN [version 1.2 PL1]


Hi,
 
I'm creating a list of molecular graphic packages for the "Frequently Asked
Questions" of the Computational Chemistry List.
 
The programs must be able to display a molecular structure from Cartesian,
internal, or fractional coordinates. 
 
A first version of the database is available in the pub/vdvk directory at
netcom5.netcom.com and at the osc server.
The actual list of programs described in the database is :
Subject: PC MOBY
Subject: Unix/VMS AMPAC with Graphical User Interface
Subject: UNIX MOIL-View
Subject: SGI INTERCHEM
Subject: Unix, VMS, POSIX, DOS, LINUX, SUN-OS : WHAT IF
Subject: Macintosh CSC_Chem3D_Plus
Subject: Mac Ball & Stick
Subject: Mac PC  ALCHEMY III
Subject: PC STR3DI.EXE, Ver. 6.30
Subject: CRAY/SGI/X-Window UniChem
 
 
If you are an author or distributor of such program, could you please send me
the appended form.
If you are aware of other programs, could you please forward this message to
the author or distributor of the missing software.
 
 
Thanks in advance for your cooperation,
 
Didier Vanderveken
Catalytica Inc.                                email: vdvk@netcom.com
430 Ferguson Drive                             phone: +1-415-940-6241
Mountain View CA 94043-5272                    fax:   +1-415-960-0127
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 
The format of the database is like a mailbox. You are able to read it with
your mail reader. I would like to limit my job to the merging of all emails.
Anonymous posting will not be accepted and your email address will appear
in the database. 
 
The subject line MUST be the type of computer (UNIX, PC, Mac) and the name of
the program, like: UNIX MyProgram 
 
Feel free to remove a line or to duplicate a line. Each line must start with
one of the defined keyword. If you would like to see more keywords, send me a
separate email. 
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 
Program_Name:
Program_Version: latest version available
Program_Date: date of the latest version 
Topic: simple_molecule, drug, crystal, polymer, protein, inorganic, ...
Bibliographic_Ref: If you published an article about your program
Input_Format: PDB, CSD, ORTEP, XYZ, MOPAC, ...
Output_Format: PDB, CSD, ORTEP, XYZ, ...
Molecular_Model: wire, stick, stick_and_ball, CPK, ribbon, alpha_trace, ...
Output_Type: display, PostScript, HPGL, PICT, GIF, ...
Operating_System: Unix, Mac, MSDOS, Windows, ...
Computer_Type: IBM RS/6000, SGI Indigo, ...
Hardware_Requested: dials, coprocessor, ...
Hardware_Supported: stereo_display, ...
Graphic_Library: GL, PHIGS, X11, ...
Distribution_Method: public_domain, freeware, shareware, commercial, ...
Ftp_Site:
Ftp_Directory:
Price_Academic:
Price_Private:
Contact_Affiliation:
Contact_Name:
Contact_Phone: +1-234-567-8901 (international number of the headquarters)
Contact_Fax:
Contact_Email:

From owner-software@net.bio.net Sun Nov 07 22:00:00 1993
Path: biosci!micro.uct.ac.za!ED
From: ED@micro.uct.ac.za ("RYBICKI,  ED")
Newsgroups: bionet.software
Subject: Re: Windows telnet and ftp software
Message-ID: <MAILQUEUE-101.931108095035.597@micro.uct.ac.za>
Date: 8 Nov 93 07:36:53 GMT
Sender: news@net.bio.net
Reply-To: ed@micro.uct.ac.za
Distribution: bionet
Lines: 34


> In article <9311051920.AA19760@audrey.lmf.org>, 
<jim@AUDREY.LMF.ORG> writes:
>  
> > I am a Windows PC user. However I cuurently use a dos Kermit to 
do Telnet
> > and a dos FTP. Are there any good WINDOWS software to do telnet 
and FTP??
...

> 
> I've been using Chameleon TCP/IP ... The one drawback is price, 
about $400 for the package. It 
> also includes a WinSock interface that works great with the 
Gopher+ client I've 
> got running.

Try QVTNET from your favourite FTP site: shareware, excellent telnet 
capabilities, good newsreader, good ftp, mailer...I regularly have 
up to 3 VAX windows open simultaneously and an ftp session grinding 
away, then read mail!  Also newest version(s? up to 3.8 now) support 
Winsock 1.1, otherwise packet-driven.

  ____________________________________________________________________
 | Ed Rybicki, PhD             |                                      |
 | (ed@micro.uct.ac.za)        |      "Lord, won't you buy me         |
 | Dept Microbiology           |          A Mer-ce-des Benz           |
 | University of Cape Town     |     My friends all have Porsches     |
 |                             |          I must make amends..."      |                      |
 | Private Bag, Rondebosch     |                                      |
 | 7700, South Africa          |           - Janis Joplin             |
 | fax: 27-21-650 4023         |            (Pearl, 1971)             |
  --------------------------------------------------------------------


From owner-software@net.bio.net Sun Nov 07 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!pipex!sunic!news.funet.fi!news.csc.fi!funic!nic.funet.fi!csc.fi!harper
From: Rob.Harper@csc.fi (Rob Harper)
Newsgroups: bionet.software
Subject: Lynx 2.0.12 now available!
Message-ID: <199311080851.AA18928@csc.fi>
Date: 8 Nov 93 08:51:30 GMT
Sender: root@nic.funet.fi (The FUnny NET guru)
Organization: Finnish University & Research Network
Lines: 115


I suppose many people are becoming interested in WWW/Xmosaic
For those of you who do not have Xwindows capabilities and
would like to experiment with the World Wide Web then Lynx
will highlight options within a hypertext document and allow
you to select them by moving through the text with the tab key.

Get it if you wont give up your VT100 terminal;-)

%%%%%%%%%%%%%%%%%%%%%%%%%% CLIP %%%%%%%%%%%%%%%%%%%%%%%%%%%
Lynx Ver. 2.0.12 is now available for anonymous ftp from
 FTP2.cc.ukans.edu    as   /pub/lynx/lynx2-0-12.tar.Z

( ftp://ftp2.cc.ukans.edu/pub/lynx/lynx2-0-12.tar.Z )

Lynx is a distributed hypertext browser with full World Wide Web
and Gopher capibilities.  For an explanation of features and a demo, 
telnet to "kufacts.cc.ukans.edu" and login as "www".

This release of Lynx has been compiled by me on the following platforms:

 o  IBM (AIX 3.2)
 o  DEC Ultrix
 o  DEC Alpha OSF/1
 o  Sun 4
 o  NeXT (Mine is an older version of NeXTStep, but it should work 
          with newer ones too.)
 o  VMS (Multinet)

This release is rumored to compile on the following platforms:
 o  HP-UX (snake)
 o  Solaris 2
 o  SVR4
 o  VMS (UCX)
 o  LINUX
 o  SGI 
 o  SUN 3
 o  AIX 3.1
 o  NeXTStep 3.x

Binaries for the following platforms are available:

 o  IBM (AIX 3.2, will work with 3.1 as well)
 o  Ultrix
 o  Alpha OSF/1
 o  Sun 4
 o  VMS (Multinet)
 
A listserv list has been created for the distribution of
Lynx related information and updates.
  o  Lynx-Dev@ukanaix.cc.ukans.edu
 
Send a subscribe request to listserv@ukanaix.cc.ukans.edu to
be added to the list.  All new releases will be anounced on this
list.  Please do not send subscribe requests to the the Lynx-Dev
list directly.

    The following new features have been added:

* added preliminary level 1 forms support.
  (Parsing and user display works, but nothing else)
  I'm looking for input on the forms interface!
* interuptable I/O added.  Hit the 'a' key for "abort" during
  transfers.  Its a little flakey right now during connections,
  but it works most of the time :)  
* local HTML documents ending in .html can now be referenced with
  just a filename and/or path from the command line.
* Added preloaded searches to gopher URL's.  They previously
  didn't work.  This is readily apparent as preloaded CSO
  searches, which alot of people wanted. (bug?)
* added descriptive subject lines to files mailed from lynx
* added "X-within-URL" mail header line to specify which
  URL from which files, comments, and mailto links are sent from.
* The user's specified editor is now spawned for mail messages.
  If no editor is defined or if the user is anonymous, the built-in 
  lynx mail sender is used.
* added progress messages to all transfers.
* added -cache=# command line option to specify the number
  of WWW documents cached in memory.
* added VMS port fixes from Foteos Macrides.  Lynx now
  compiles and works on VMS! (bug?)
* Moved many configuration options including printer setup to 
  lynx.cfg file.  The default placement of the lynx.cfg file
  will be /usr/local/lib & sys$public.  Printers can now be
  configured without recompiling!
* Removed STARTDIR variable from userdefs.h  STARTDIR is now inferred
  from the STARTFILE. (doesn't effect HTML files)
* Ported to SVR4 courtesy of Nickolay Saukh (from Russia, Wow this is
  really getting around!) 
* Uneditable documents don't get refetched. (Nickolay Saukh)
* National language support through LOCALE
  (instead of ISOLATIN1), protected by #ifdef LOCALE (Nickolay Saukh)


   A partial list of bugs that have been fixed

* disabled FTP connection caching to help fix multiple FTP problems
* fixed a bunch of gopher holes
* gopher lists are turned into URL's now instead of lynx
  internal format document links
* removed old hytelnet compatibility code which looked in
  multiple directories to find the correct file.  If you still
  need this capibility talk to me.
* changed all static data structures to be dynamic
  This was a pretty major change of code which may add several
  bugs. :)
* rewrote parse_links routine to make it more efficient and to
  work with dynamic structures.
* added VMS port fixes from Foteos Macrides.  Lynx now
  compiles and works on VMS!
* fixed ftp bug in WWWlib that didn't de-escape URL's before
  sending request to FTP server.
* fixed coredump bug for some files with no links.
* Fixed bug with only one link selectable out of many on the last line
  of the display.

From owner-software@net.bio.net Sun Nov 07 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!uunet!munnari.oz.au!metro!usage!news
From: Shaharin Yussof
Newsgroups: bionet.software
Subject: Re: Trumpet and winsoc
Message-ID: <1993Nov8.005857.8220@usage.csd.unsw.OZ.AU>
Date: 8 Nov 93 00:58:57 GMT
Sender: news@usage.csd.unsw.OZ.AU
Organization: Department of Safety Science
Lines: 34
Nntp-Posting-Host: 149.171.28.200
X-Newsreader: <WinQVT/Net v3.9>

In article <fenton.752530902@news.cso.uiuc.edu> fenton@nemo.life.uiuc.edu (Jim Fenton) writes:
>Shaharin Yussof writes:
>
>>In article <16C7CDC3A.030NEILV@Witsvma.wits.ac.za> 030NEILV@Witsvma.wits.ac.za (Neil van der Merwe) writes:
>>>Hi,
>>>Can anyone tell me where I can get hold of Trumpet and Winsoc?  I also
>>>need some info on winsoc, as I am totally unfamiliar with it.
>>>Thanks in advance,
>>>Neil
>
>>Try anonymous ftp to biochemistry.cwru.edu
>
>>You might also try the shareware QVTNET as a TCP/IP, mail, newsreader, and FTP 
>>program.  It is available in the same place.
>
>>Shaharin 
>
>Is it just me or did QVTNET work for others.  I never got the lpr print stuff
>to work properly, the windows version was amazingly slow and wouldn't
>work with our NFS network (yes, we have a weird mix of unix and pc's that
>adds some difficulties).  I'm much more happy since I turned our PC's running
>windows into X terminals with eXceed/W for windows.  Of course, this isn't
>shareware, but it wouldn't surprise me to find that there are public domain
>versions of X emulators available.
>-- 
>  Jim Fenton	 fenton@nemo.life.uiuc.edu

Frankly, I haven't the foggiest idea whether or not the lpr stuff works.  We 
don't run a UNIX machine in our department, and our remote printing is done 
using Windows for Workgroups.  

All the other bits work wonderfully though.

Shaharin

From owner-software@net.bio.net Sun Nov 07 22:00:00 1993
Path: biosci!news.cs.umb.edu!hsdndev!howland.reston.a