From owner-software@net.bio.net Sat Oct 01 23:00:00 1994
Path: biosci!agate!spool.mu.edu!uwm.edu!rutgers!netnews.upenn.edu!news.drexel.edu!dunx1.ocs.drexel.edu!dunx1.ocs.drexel.edu!not-for-mail
From: st93mey7@dunx1.ocs.drexel.edu (Frederick Thum)
Newsgroups: bionet.software
Subject: Tierra on the Internet
Date: 2 Oct 1994 15:25:33 -0400
Organization: Drexel University, Phila. Pa.
Lines: 20
Message-ID: <36n1fd$qid@dunx1.ocs.drexel.edu>
NNTP-Posting-Host: dunx1.ocs.drexel.edu
X-Newsreader: TIN [version 1.2 PL2]


I have obtained a copy of Tierra, a program that simulates an
evolution and an ecosystem through computer code.  

I have got the regular version of Tierra working fine (with the exception
that it would not compile on a DEC/4000), but I would like to
run it so that it could share genebanks with other computers running it
over the Internet.  I got the copy of NeTierra, but the instructions for
setup are unclear.

Has anyone done this?

Any help would be appreciated

- Fred Thum
-- 
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
                Frederick L. Thum III   (st93mey7@post.drexel.edu)
                    "Diatoms are as diatoms do." - Forrest Gump
-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=

From owner-software@net.bio.net Sat Oct 01 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!wupost!news.miami.edu!miasun.med.miami.edu!FirstLight.chroma.med.miami.edu
From: rb@chroma.med.miami.edu (Richard J. Bookman)
Newsgroups: bionet.software
Subject: Re: Scientific Graphing
Date: Sun,  2 Oct 1994 15:04:14 -0500
Organization: University of Miami School of Medicine
Lines: 34
Distribution: world
Message-ID: <9410021504.AA14195@FirstLight.chroma.med.miami.edu>
References: <199409241557.IAA24705@net.bio.net>
Reply-To: rb@chroma.med.miami.edu (Richard J. Bookman)
NNTP-Posting-Host: mac2.med.miami.edu
X-Newsreader: InterCon TCP/Connect II 1.2.1

In article <199409241557.IAA24705@net.bio.net>, MJOHNSO3@UA1VM.UA.EDU (Mark J) 
writes:


> Anybody have email or snailmail addresses for: 
>       MicroCal Software - makers of "Origin" 
>       whoever sells or makes "Kaleidagraph" 
>       the creators/sellers of "Igor Pro" 


> I am looking for something as easy to use and as complete as the 
> Sigmaplot pack age is on the Windows platform - but made for use on a 
> Mac Power PC. 
>  
> Thanks in advance. = Mark J 
>  

It is my understanding that the native version of IGOR Pro
is nearly ready to go out for beta testing. The original
timetable was to have it out by the end of the year.
An October release for beta-testing is consistent with the
original goal.

You can contact the creators (good word choice!) as:
wavemetrics@applelink.apple.com


R. Bookman
University of Miami School of Medicine






From owner-software@net.bio.net Sat Oct 01 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!wupost!news.miami.edu!miasun.med.miami.edu!FirstLight.chroma.med.miami.edu
From: rb@chroma.med.miami.edu (Richard J. Bookman)
Newsgroups: bionet.software,bionet.virology
Subject: Re: Virology Teaching Resources on the Internet
Date: Sun,  2 Oct 1994 15:14:22 -0500
Organization: University of Miami School of Medicine
Lines: 37
Distribution: world
Message-ID: <9410021514.AA22789@FirstLight.chroma.med.miami.edu>
References: <sspencer-011094165505@ted.bocklabs.wisc.edu>
Reply-To: rb@chroma.med.miami.edu (Richard J. Bookman)
NNTP-Posting-Host: mac2.med.miami.edu
X-Newsreader: InterCon TCP/Connect II 1.2.1
Xref: biosci bionet.software:9499 bionet.virology:904




> SHAMELESS PLUG: 
> I am currently looking for a job in New Zealand or Australia, 
> particularly one related to bioinformatics. If you have any leads for me, 
> please email me. 
> Thank you! 
> ------ 
>  
> Stephan Spencer 
> Developer and Administrator of WWW Server for Virology 
> Institute for Molecular Virology 
> University of Wisconsin-Madison 
> sspencer@rhino.bocklabs.wisc.edu 
>  

You may want to contact my colleague David Adams who is,
unfortunately, leaving Miami to take a chair in Brisbane.

dadams@mednet.med.miami.edu

He is an electrophysiologist, but he might know of
some opportunities to do things right that are
opening up in Brisbane.

Also, contact Axon Research (Dr. Alan Finkel, Pres.)
in Melbourne...they do a lot of software development
for physiology and biophysics.

good luck,

R. Bookman





From owner-software@net.bio.net Sat Oct 01 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!newsserver.jvnc.net!raffles.technet.sg!merlion.singnet.com.sg!merlion.singnet.com.sg!arman
From: arman@merlion.singnet.com.sg (Arman Esmaili)
Newsgroups: bionet.software
Subject: Help Desk Software Wanted
Date: 1 Oct 1994 05:17:24 GMT
Organization: Singapore Telecom Internet Service
Lines: 11
Message-ID: <36ird4$dol@merlion.singnet.com.sg>
NNTP-Posting-Host: merlion.singnet.com.sg
X-Newsreader: TIN [version 1.2 PL2]


My company is looking for a Help Desk logging/inquiry software to run on 
a LAN.  Could anyone recommend any to us?

Thanks
Arman.
--
-----------------------------------------------------------------------------
arman@singnet.com.sg

Arman & Janice Esmaili

From owner-software@net.bio.net Sat Oct 01 23:00:00 1994
Path: biosci!agate!ihnp4.ucsd.edu!scripps.edu!misrael
From: misrael@scripps.edu (Mark Israel)
Newsgroups: bionet.molbio.proteins,bionet.software
Subject: Re: program to obtain 3d coordinates from stereo pictures
Date: 2 Oct 1994 19:51:51 GMT
Organization: The Scripps Research Institute, La Jolla, California, USA
Lines: 29
Message-ID: <36n30n$nou@riscsm.scripps.edu>
References: <9410011655.AA08195@nick.med.usf.edu>
NNTP-Posting-Host: struct.scripps.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
Xref: biosci bionet.molbio.proteins:2795 bionet.software:9500

In article <9410011655.AA08195@nick.med.usf.edu>, gquinn@NICK.MED.USF.EDU (Gregory Quinn) writes:

> Does anyone know anything about the program that can produce 3d 
> coordinates from stereo pictures of proteins?

Here's some info on it that was recently posted to bionet.xtallography:

| Subject: Re:Extracting Coorodinates from Stereo Diagrams.
| Newsgroups: bionet.xtallography
| From: raman@BIOC01.UTHSCSA.EDU (C.S.RAMAN)
| Organization: BIOSCI International Newsgroups for Molecular Biology
| Date: 16 Aug 1994 06:41:55 -0700
| Message-ID: <9408161342.AA02724@bioc01.uthscsa.edu>
| 
| [...]
| 
| In addition to what I had told you about its existence in the PDB, here
| is what I recently found.  The program is still called STEREO and has
| been substantially modified (original version 1974 Michael Rossmann) by
| Jin-Bi Dai also at purdue.  The latest version of the program is dated
| 1994 and you can obtain a copy of the source and associated man page
| from the latter author.
| 
| Jin-Bi Dai can be reached via e-mail at:
| 
| b4x@mace.cc.purdue.edu

--
misrael@scripps.edu			Mark Israel

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!sunic!pipex!news.sprintlink.net!howland.reston.ans.net!agate!cat.cis.Brown.EDU!news2.near.net!das-news.harvard.edu!husc-news.harvard.edu!husc-news.harvard.edu!news
Newsgroups: bionet.software
Subject: protein homology modelling program
Message-ID: <1994Oct2.191304.35069@hulaw1.harvard.edu>
From: sali@tamika.harvard.edu (Andrej Sali)
Date: 2 Oct 94 19:13:02 EDT
Keywords: program, homology modelling, comparative modelling, protein modelling
Nntp-Posting-Host: tamika.harvard.edu
Lines: 73

                                  MODELLER
          PROTEIN MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS
                        MODELLER 11, October 1, 1994
                                                                 
                    Copyright(c) 1989-1994 Andrej Sali           
                            All Rights Reserved                  

                           Written by Andrej Sali                
             Birkbeck College, University of London, London, UK  
                 Imperial Cancer Research Fund, London, UK       
                     Harvard University, Cambridge, USA          

Andrej Sali, Department of Chemistry, Harvard University, 12 Oxford St,
Cambridge, MA 02138, USA. Tel: (617) 495 1775. Fax: (617) 496 3204.
E-mail: sali@tammy.harvard.edu.


** DESCRIPTION:

MODELLER is most frequently used for homology or comparative modeling
of protein three-dimensional structure: the user provides an alignment
of a sequence to be modeled with known related structures and MODELLER
will automatically calculate a full-atom model. More generally, MODELLER 
models protein 3D structure by satisfaction of spatial restraints 
(A. Sali & T.L. Blundell. J.Mol.Biol. 234, 779-815, 1993). In principle, 
the restraints can be derived from a number of different sources. These 
include homologous structures (comparative modeling), NMR experiments 
(NMR refinement), rules of secondary structure packing (combinatorial 
modeling), cross-linking experiments, fluorescence spectroscopy, image
reconstruction in electron microscopy, site-directed mutagenesis, 
intuition, residue-residue and atom-atom potentials of mean force, etc. 
The output of MODELLER is a 3D structure of a protein that satisfies 
these restraints as well as possible. The optimization is carried out 
by the variable target function procedure employing methods of conjugate 
gradients and molecular dynamics with simulated annealing. The program 
includes a 100-page manual. MODELLER is written in Fortran and is meant 
to run on a UNIX system.


** DISTRIBUTION:

MODELLER is available free of charge to non-profit institutions.

First, please use the anonymous ftp account on tammy.harvard.edu (IP
128.103.96.19) to copy the files from the pub/modeller directory to
your computer.  Print and sign the license form (academic-license.ps)
and mail or fax it to Andrej Sali. You will then receive the
encryption key (MODELLER_KEY) with which you will be able to unpack
the encrypted distribution file (modeller11-exec.tar.Z.cr). See file
INSTALLATION for installation instructions.

MODELER is also available as part of QUANTA, a large program with many
other functionalities including interactive graphics, CHARMm, and 
X-PLOR. If you are interested in this commercial version please contact 
Ms. Jo Ellen Collins at Molecular Simulations Inc, 16 New England 
Executive Park, Burlington, MA 01803-5297, tel: (617) 229 9800, 
fax: (617) 229 9899, email: jcollins@msi.com.



** CONTENTS:

src\                sources or executables for MODELLER and associated 
                    programs
modlib\             libraries and data files for the programs
scripts\            script files used to compile and use MODELLER
doc\                MODELLER documentation
Makefile            Makefile for compiling/installing MODELLER modules; 
                    used by the Install script
modeller11.README   this file
INSTALLATION        how to install MODELLER
Install             compilation and installation script
tests\              tests and examples

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!sunic!pipex!news.sprintlink.net!howland.reston.ans.net!agate!cat.cis.Brown.EDU!news2.near.net!das-news.harvard.edu!husc-news.harvard.edu!husc-news.harvard.edu!news
Newsgroups: bionet.software
Subject: protein homology modelling program
Message-ID: <1994Oct2.191159.35068@hulaw1.harvard.edu>
From: sali@tamika.harvard.edu (Andrej Sali)
Date: 2 Oct 94 19:11:58 EDT
Keywords: program, homology modelling, comparative modelling, protein modelling
Nntp-Posting-Host: tamika.harvard.edu
Lines: 73

                                  MODELLER
          PROTEIN MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS
                        MODELLER 11, October 1, 1994
                                                                 
                    Copyright(c) 1989-1994 Andrej Sali           
                            All Rights Reserved                  

                           Written by Andrej Sali                
             Birkbeck College, University of London, London, UK  
                 Imperial Cancer Research Fund, London, UK       
                     Harvard University, Cambridge, USA          

Andrej Sali, Department of Chemistry, Harvard University, 12 Oxford St,
Cambridge, MA 02138, USA. Tel: (617) 495 1775. Fax: (617) 496 3204.
E-mail: sali@tammy.harvard.edu.


** DESCRIPTION:

MODELLER is most frequently used for homology or comparative modeling
of protein three-dimensional structure: the user provides an alignment
of a sequence to be modeled with known related structures and MODELLER
will automatically calculate a full-atom model. More generally, MODELLER 
models protein 3D structure by satisfaction of spatial restraints 
(A. Sali & T.L. Blundell. J.Mol.Biol. 234, 779-815, 1993). In principle, 
the restraints can be derived from a number of different sources. These 
include homologous structures (comparative modeling), NMR experiments 
(NMR refinement), rules of secondary structure packing (combinatorial 
modeling), cross-linking experiments, fluorescence spectroscopy, image
reconstruction in electron microscopy, site-directed mutagenesis, 
intuition, residue-residue and atom-atom potentials of mean force, etc. 
The output of MODELLER is a 3D structure of a protein that satisfies 
these restraints as well as possible. The optimization is carried out 
by the variable target function procedure employing methods of conjugate 
gradients and molecular dynamics with simulated annealing. The program 
includes a 100-page manual. MODELLER is written in Fortran and is meant 
to run on a UNIX system.


** DISTRIBUTION:

MODELLER is available free of charge to non-profit institutions.

First, please use the anonymous ftp account on tammy.harvard.edu (IP
128.103.96.19) to copy the files from the pub/modeller directory to
your computer.  Print and sign the license form (academic-license.ps)
and mail or fax it to Andrej Sali. You will then receive the
encryption key (MODELLER_KEY) with which you will be able to unpack
the encrypted distribution file (modeller11-exec.tar.Z.cr). See file
INSTALLATION for installation instructions.

MODELER is also available as part of QUANTA, a large program with many
other functionalities including interactive graphics, CHARMm, and 
X-PLOR. If you are interested in this commercial version please contact 
Ms. Jo Ellen Collins at Molecular Simulations Inc, 16 New England 
Executive Park, Burlington, MA 01803-5297, tel: (617) 229 9800, 
fax: (617) 229 9899, email: jcollins@msi.com.



** CONTENTS:

src\                sources or executables for MODELLER and associated 
                    programs
modlib\             libraries and data files for the programs
scripts\            script files used to compile and use MODELLER
doc\                MODELLER documentation
Makefile            Makefile for compiling/installing MODELLER modules; 
                    used by the Install script
modeller11.README   this file
INSTALLATION        how to install MODELLER
Install             compilation and installation script
tests\              tests and examples

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!sunic!pipex!news.sprintlink.net!howland.reston.ans.net!agate!cat.cis.Brown.EDU!news2.near.net!das-news.harvard.edu!husc-news.harvard.edu!husc-news.harvard.edu!news
Newsgroups: bionet.software
Subject: protein homology modelling program
Message-ID: <1994Oct2.191334.35070@hulaw1.harvard.edu>
From: sali@tamika.harvard.edu (Andrej Sali)
Date: 2 Oct 94 19:13:33 EDT
Keywords: program, homology modelling, comparative modelling, protein modelling
Nntp-Posting-Host: tamika.harvard.edu
Lines: 73

                                  MODELLER
          PROTEIN MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS
                        MODELLER 11, October 1, 1994
                                                                 
                    Copyright(c) 1989-1994 Andrej Sali           
                            All Rights Reserved                  

                           Written by Andrej Sali                
             Birkbeck College, University of London, London, UK  
                 Imperial Cancer Research Fund, London, UK       
                     Harvard University, Cambridge, USA          

Andrej Sali, Department of Chemistry, Harvard University, 12 Oxford St,
Cambridge, MA 02138, USA. Tel: (617) 495 1775. Fax: (617) 496 3204.
E-mail: sali@tammy.harvard.edu.


** DESCRIPTION:

MODELLER is most frequently used for homology or comparative modeling
of protein three-dimensional structure: the user provides an alignment
of a sequence to be modeled with known related structures and MODELLER
will automatically calculate a full-atom model. More generally, MODELLER 
models protein 3D structure by satisfaction of spatial restraints 
(A. Sali & T.L. Blundell. J.Mol.Biol. 234, 779-815, 1993). In principle, 
the restraints can be derived from a number of different sources. These 
include homologous structures (comparative modeling), NMR experiments 
(NMR refinement), rules of secondary structure packing (combinatorial 
modeling), cross-linking experiments, fluorescence spectroscopy, image
reconstruction in electron microscopy, site-directed mutagenesis, 
intuition, residue-residue and atom-atom potentials of mean force, etc. 
The output of MODELLER is a 3D structure of a protein that satisfies 
these restraints as well as possible. The optimization is carried out 
by the variable target function procedure employing methods of conjugate 
gradients and molecular dynamics with simulated annealing. The program 
includes a 100-page manual. MODELLER is written in Fortran and is meant 
to run on a UNIX system.


** DISTRIBUTION:

MODELLER is available free of charge to non-profit institutions.

First, please use the anonymous ftp account on tammy.harvard.edu (IP
128.103.96.19) to copy the files from the pub/modeller directory to
your computer.  Print and sign the license form (academic-license.ps)
and mail or fax it to Andrej Sali. You will then receive the
encryption key (MODELLER_KEY) with which you will be able to unpack
the encrypted distribution file (modeller11-exec.tar.Z.cr). See file
INSTALLATION for installation instructions.

MODELER is also available as part of QUANTA, a large program with many
other functionalities including interactive graphics, CHARMm, and 
X-PLOR. If you are interested in this commercial version please contact 
Ms. Jo Ellen Collins at Molecular Simulations Inc, 16 New England 
Executive Park, Burlington, MA 01803-5297, tel: (617) 229 9800, 
fax: (617) 229 9899, email: jcollins@msi.com.



** CONTENTS:

src\                sources or executables for MODELLER and associated 
                    programs
modlib\             libraries and data files for the programs
scripts\            script files used to compile and use MODELLER
doc\                MODELLER documentation
Makefile            Makefile for compiling/installing MODELLER modules; 
                    used by the Install script
modeller11.README   this file
INSTALLATION        how to install MODELLER
Install             compilation and installation script
tests\              tests and examples

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!wupost!kuhub.cc.ukans.edu!mbcf!heath
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Message-ID: <1994Oct1.142817.8747@mbcf>
From: heath@mbcf.stjude.org (Richard)
Date: 1 Oct 94 14:28:17 -600
References: <sspencer-260994203725@f181-207.net.wisc.edu>   
 <tan-2809941449410001@smac.ethz.ch> 
 <1994Sep29.181744.29696@genes.icgeb.trieste.it>
Organization: St. Jude Children's Research Hospital
Lines: 34
Xref: biosci bionet.molbio.methds-reagnts:19151 bionet.software:9509

In article <1994Sep29.181744.29696@genes.icgeb.trieste.it>, raffa@biocell.irmkant.rm.cnr.it (MEG-CNR) writes:
> In article <tan-2809941449410001@smac.ethz.ch>
> tan@aeolus.vmsmail.ethz.ch (Song Tan) writes:
> ........
>> 
>> Technical support by email would be my highest priority.  
>> .........
>> Biolabs has very good email technical support and I think it's in the best > interest of other biotech companies to offer similar services.  
>> 
>> Technical notes online would be next in line.  It would allow the
>> researcher to get the information more efficiently and I believe it's also
>> economically beneficial to Promega.
>> 
>> -- 
>> Song Tan
>> email:  tan@aeolus.vmsmail.ethz.ch
> 
> I definitively agree.
> Meanwhile could you provide the Biolabs e-mail address?
> 
> Raffaele Matteoni
> Inst Cell Biology CNR
> Roma I-OO137 Italy
> 
> raffa@biocell.irmkant.rm.cnr.it


I agree with all of the above!

And here is NEB's email from the back of their catalog:

	info@neb.com

Richard

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Path: biosci!daresbury!bioftp.unibas.ch!citi2.fr!jussieu.fr!pasteur.fr!univ-lyon1.fr!swidir.switch.ch!newsfeed.ACO.net!Austria.EU.net!EU.net!uunet!cs.utexas.edu!howland.reston.ans.net!news.sprintlink.net!demon!pplros.demon.co.uk!tomlinson
From: Anthony Tomlinson <tomlinson@pplros.demon.co.uk>
Subject: Re: Promega on the Internet
Message-ID: <Cx3qJ4.Aos@demon.co.uk>
X-Xxmessage-Id: <AAB5D8ED83011522@pplros.demon.co.uk>
X-Xxdate: Mon, 3 Oct 1994 15:51:09 GMT
Sender: news@demon.co.uk (Usenet Administration)
Nntp-Posting-Host: pplros.demon.co.uk
Organization: PPL Therapeutics
X-Newsreader: Nuntius Version 1.2
References: <sspencer-260994203725@f181-207.net.wisc.edu> <1994Sep29.181744.29696@genes.icgeb.trieste.it> <1994Sep30.095101.11072@rzu-news.unizh.ch>
Date: Mon, 3 Oct 1994 14:49:52 GMT
Lines: 19
Xref: biosci bionet.molbio.methds-reagnts:19134 bionet.software:9508

In article <sspencer-260994203725@f181-207.net.wisc.edu> Stephan Spencer,
sspencer@rhino.bocklabs.wisc.edu writes:
>I (and Promega) would like to know who out there would like to see
Promega
>on the World Wide Web, and what you would like to see (catalog, technical
>notes, online ordering, tech support, etc...)
>
>Second question.. would you use their services online? Would you order
>online?


I agree with everyone else - New product info, technical bulletins
and protocol updates would all be appreciated on www,
and an email address for specific questions (a la NEB)
will surely be a must for all molbiol suppliers in a
few years.  Unsolicited advertising via email would be
intolerable though, and I couldn't order via the Internet
because of the ordering system we operate.  Maybe if more
companies were online, ordering depts might come around....

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!CS.Arizona.EDU!uunet!europa.eng.gtefsd.com!uhog.mit.edu!news.mtholyoke.edu!news.umass.edu!news2.near.net!das-news.harvard.edu!husc-news.harvard.edu!husc-news.harvard.edu!news
Newsgroups: bionet.software
Subject: homology modelling program
Message-ID: <1994Oct2.191512.35071@hulaw1.harvard.edu>
From: sali@tamika.harvard.edu (Andrej Sali)
Date: 2 Oct 94 19:15:11 EDT
Keywords: protein modelling, homology modelling, comparative modelling
Nntp-Posting-Host: tamika.harvard.edu
Lines: 73

                                  MODELLER
          PROTEIN MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS
                        MODELLER 11, October 1, 1994
                                                                 
                    Copyright(c) 1989-1994 Andrej Sali           
                            All Rights Reserved                  

                           Written by Andrej Sali                
             Birkbeck College, University of London, London, UK  
                 Imperial Cancer Research Fund, London, UK       
                     Harvard University, Cambridge, USA          

Andrej Sali, Department of Chemistry, Harvard University, 12 Oxford St,
Cambridge, MA 02138, USA. Tel: (617) 495 1775. Fax: (617) 496 3204.
E-mail: sali@tammy.harvard.edu.


** DESCRIPTION:

MODELLER is most frequently used for homology or comparative modeling
of protein three-dimensional structure: the user provides an alignment
of a sequence to be modeled with known related structures and MODELLER
will automatically calculate a full-atom model. More generally, MODELLER 
models protein 3D structure by satisfaction of spatial restraints 
(A. Sali & T.L. Blundell. J.Mol.Biol. 234, 779-815, 1993). In principle, 
the restraints can be derived from a number of different sources. These 
include homologous structures (comparative modeling), NMR experiments 
(NMR refinement), rules of secondary structure packing (combinatorial 
modeling), cross-linking experiments, fluorescence spectroscopy, image
reconstruction in electron microscopy, site-directed mutagenesis, 
intuition, residue-residue and atom-atom potentials of mean force, etc. 
The output of MODELLER is a 3D structure of a protein that satisfies 
these restraints as well as possible. The optimization is carried out 
by the variable target function procedure employing methods of conjugate 
gradients and molecular dynamics with simulated annealing. The program 
includes a 100-page manual. MODELLER is written in Fortran and is meant 
to run on a UNIX system.


** DISTRIBUTION:

MODELLER is available free of charge to non-profit institutions.

First, please use the anonymous ftp account on tammy.harvard.edu (IP
128.103.96.19) to copy the files from the pub/modeller directory to
your computer.  Print and sign the license form (academic-license.ps)
and mail or fax it to Andrej Sali. You will then receive the
encryption key (MODELLER_KEY) with which you will be able to unpack
the encrypted distribution file (modeller11-exec.tar.Z.cr). See file
INSTALLATION for installation instructions.

MODELER is also available as part of QUANTA, a large program with many
other functionalities including interactive graphics, CHARMm, and 
X-PLOR. If you are interested in this commercial version please contact 
Ms. Jo Ellen Collins at Molecular Simulations Inc, 16 New England 
Executive Park, Burlington, MA 01803-5297, tel: (617) 229 9800, 
fax: (617) 229 9899, email: jcollins@msi.com.



** CONTENTS:

src\                sources or executables for MODELLER and associated 
                    programs
modlib\             libraries and data files for the programs
scripts\            script files used to compile and use MODELLER
doc\                MODELLER documentation
Makefile            Makefile for compiling/installing MODELLER modules; 
                    used by the Install script
modeller11.README   this file
INSTALLATION        how to install MODELLER
Install             compilation and installation script
tests\              tests and examples

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!CS.Arizona.EDU!news.Arizona.EDU!hamblin.math.byu.edu!sol.ctr.columbia.edu!spool.mu.edu!howland.reston.ans.net!swiss.ans.net!solaris.cc.vt.edu!news.duke.edu!godot.cc.duq.edu!toads.pgh.pa.us!newsfeed.pitt.edu!dsinc!ub!galileo.cc.rochester.edu!news
From: CAAL@BPHVAX.BIOPHYSICS.ROCHESTER.EDU (Charles Alexander)
Subject: Seqapp problem
Message-ID: <1994Oct3.144031.5758@galileo.cc.rochester.edu>
Sender: news@galileo.cc.rochester.edu
Nntp-Posting-Host: bphvax.biophysics.rochester.edu
Organization: DEPT. OF BIOPHYSICS, UNIVERSITY OF ROCHESTER
Date: Mon, 3 Oct 94 14:40:31 GMT
X-News-Reader: VMS NEWS v1.25
Lines: 21

Hello all,

I have been trying to use Don Gilbert's freeware sequence editing program for
the Mac, Seqapp.  However, I'm having a difficult time saving sequences in the
single-sequence or multi-sequence editor window.  When you specify the save
option everything seems to work fine but when you try to re-open it later the
sequence is missing, although the file name exists.  

I'm sure the solution is embarrasingly simple but for the life of me I cannot 
figure it out.

The problem also seems intermittent.  Any suggestions ?

Thank you

Charles Alexander

Div. of Medical Informatics
University of Rochester
Rochester, New York
e-mail: caal@bphvax.biophysics.rochester.edu

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!eunet.no!nuug!nac.no!nntp.uio.no!NewsWatcher!user
From: olam@radium.uio.no (Ola Myklebost)
Newsgroups: bionet.software
Subject: Re: sequence alignment software
Date: Mon, 03 Oct 1994 12:45:46 +0100
Organization: Inst for Cancer Research, Oslo
Lines: 15
Distribution: world
Message-ID: <olam-0310941245460001@129.240.38.55>
References: <9409212316.AA01445@sprcore.bih.harvard.edu> <35spl4$auj@news.rz.uni-duesseldorf.de>
NNTP-Posting-Host: pcdnr05.uio.no

I recently tried a new co-processor card for PC/Windows which soon is to
be marketed by the Norwegian company MedProbe. The card contains a custom
made homology-searcing chip, and with its accompanying software you may
load genbank etc in RAM and search homologies VERY fast (minutes).

It was said to be much cheaper than competing products.

Ola

-- 
Ola Myklebost                   Email  ola.myklebost@labmed.uio.no
Dept of Tumor Biology
Inst for Cancer Research        Tel +47-2293-4299
The Norwegian Radium Hospital   Fax +47-2252-2421
N-0310 OSLO, Norway

From owner-software@net.bio.net Sun Oct 02 23:00:00 1994
Path: biosci!s.u-tokyo!news.tisn.ad.jp!news.u-tokyo.ac.jp!sinetnews!daffy!uwvax!uchinews!vixen.cso.uiuc.edu!howland.reston.ans.net!news.sprintlink.net!redstone.interpath.net!ddsw1!willis.cis.uab.edu!maze.dpo.uab.edu!ramermac.nrc.uab.edu!user
From: ramer@nrc.uab.edu (Kevin W. Ramer)
Newsgroups: bionet.software,bionet.software.acedb
Subject: Re: Mac Printing (Was Visualisation of Postscript files in Macs?)
Date: Mon, 03 Oct 1994 09:48:33 -0600
Organization: University of Alabama at Birmingham
Lines: 27
Distribution: world
Message-ID: <ramer-0310940948330001@ramermac.nrc.uab.edu>
References: <36cs42$jko@calvin.st-and.ac.uk> <rnair-290994090709@223.32.med.umich.edu> <36hd6l$ehm@lyra.csx.cam.ac.uk> <flip-3009941253220001@darwin2.bio.purdue.edu>
NNTP-Posting-Host: ramermac.nrc.uab.edu
Xref: biosci bionet.software:9507 bionet.software.acedb:447

In article <flip-3009941253220001@darwin2.bio.purdue.edu>,
flip@bogie2.bio.purdue.edu (Phillip D. Russell) wrote:
> 
> I guess you don't have the laserwriter 8 extention. You can print
> multiple pages on one sheet from any program.
> 
> The laserwriter 8 extention should be at all FTP site with
> Mac shareware.
> 

I believe that your best bet is an Apple site. e.g 
ftp.apple.com:/dts/mac/sys.soft or ftp.austin.apple.com, et. al.  I don't
think that this software is permitted on most sites.

> Flip
> 
> -- 
>          __@    Phillip "Flip" Russell  | Purdue University      __@
>   _ -_,_-\<,_flip@bogie2.bio.purdue.edu | West Lafayette, IN  _ -\<,_
>  (_)-----/-(_)           The important things...             (_)-/-(_)
>                         My bikes and my Macintosh

-- 
Kevin W. Ramer                   ramer@nrc.uab.edu
Programmer Analyst
Neurobiology Research Center
University of Alabama at Birmingham

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!swrinde!howland.reston.ans.net!EU.net!Austria.EU.net!newsfeed.ACO.net!swidir.switch.ch!univ-lyon1.fr!jussieu.fr!u-psud.fr!trefle!oger
From: oger@trefle
Newsgroups: bionet.software
Subject: Does anybody know anything about computer assisted RFLPs?
Date: 4 Oct 94 15:34:27 WET
Organization: Institut des Sciences Vegetales C.N.R.S.
Lines: 1
Message-ID: <1994Oct4.153427.1@trefle>
NNTP-Posting-Host: trefle.isv.cnrs-gif.fr



From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!swrinde!howland.reston.ans.net!EU.net!Austria.EU.net!newsfeed.ACO.net!swidir.switch.ch!univ-lyon1.fr!jussieu.fr!u-psud.fr!trefle!oger
From: oger@trefle
Newsgroups: bionet.software
Subject: Does anybody know anything about Computer Assisted RFLPs
Date: 4 Oct 94 15:44:22 WET
Organization: Institut des Sciences Vegetales C.N.R.S.
Lines: 11
Message-ID: <1994Oct4.154422.1@trefle>
NNTP-Posting-Host: trefle.isv.cnrs-gif.fr


I am actually searching for a program that would simulate the migration of DNA
fragments through an agarose or an acrylamide gel. The aim would be to generat
e RFLPs of fragments of interest, sequenced by others to compare the profiles t
o the one I got. If anyone knows anything about such a program just let me know
at the following E-mail address "oger@trefle.isv.cnrs-gif.fr" (Phil OGER) or y
ou can answer through the news network.

Thanks to any one for help.

Phil OGER

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!gs.dfn.de!immunbio.mpg.de!immunbio.mpg.de!news
Newsgroups: bionet.software
Subject: searching patterns including sek. structures
Message-ID: <1994Oct4.130524.146@immunbio.mpg.de>
From: HAESS@IMMUNBIO.MPG.DE (Gunther Häß)
Date: 4 Oct 94 13:05:23 +0100
Distribution: world
Organization: Max-Planck-Institut fuer Immunbiologie
Nntp-Posting-Host: mpi1.immunbio.mpg.de
X-News-Reader: VMS NEWS 1.24Lines: 12
Lines: 12

Hi netters

I'm searching for an amino-acid pattern searching program that includes 
the secondary structere in the pattern. It should be able to find, 
for example, a pattern of amino-acid on one side of an alpha helix
or in an angle of 90 degrees in the horizontal cut around one special 
amino-acid.
Does anybody know about a program which could perform such things?

Please answer to 

haess@immunbio.mpg.de

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!eunet.no!nuug!EU.net!howland.reston.ans.net!spool.mu.edu!mnemosyne.cs.du.edu!nyx10.cs.du.edu!not-for-mail
From: rnusbick@nyx10.cs.du.edu (robert nusbickel)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Date: 4 Oct 1994 07:22:35 -0600
Organization: University of Denver, Dept. of Math & Comp. Sci.
Lines: 13
Message-ID: <36rkur$nbj@nyx10.cs.du.edu>
References: <sspencer-260994203725@f181-207.net.wisc.edu> <tan-2809941449410001@smac.ethz.ch> <1994Sep29.181744.29696@genes.icgeb.trieste.it> <1994Oct1.142817.8747@mbcf>
NNTP-Posting-Host: nyx10.cs.du.edu
Xref: biosci bionet.molbio.methds-reagnts:19175 bionet.software:9514

This discussion about PROMEGA placing there materials on the net has got 
me thinking. How's about a service which would be sort of like a directory 
of all the suppliers information, including ordering information, 
protocols, and descriptions of the materials, and make this available 
through the net? It certainly would be advantageous to the suppliers to 
put their information into one location and it would be great for 
researchers to have only one place to check on reagents, etc. What do you 
think?

Just looking for some opinions.


Andy Nusbickel

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!urmel.informatik.rwth-aachen.de!newsserver.rrzn.uni-hannover.de!news
From: crmlbhvr@onramp.ca (Criminal Behaviour)
Subject: Lotus 1-2-3 for Windows
Message-ID: <1994Oct4.002402.6059@newsserver.rrzn.uni-hannover.de>
Sender: news@newsserver.rrzn.uni-hannover.de (News Service)
Organization: RRZN
X-Newsreader: WinVN 0.92.6
Date: Tue, 4 Oct 1994 00:24:02 GMT
Lines: 11


	I have Lotus 1-2-3 for Windows Release 5, when I try to run
	it, it displays the logo screen then halts loading.  Does
	anyone know why?  I called the Lotus support line but they
	want money to answer even 1 question.   I'm running a 486/33
	with Windows 3.1 and 8 MB of RAM.  Also I'm using Qemm 7.04
	it that makes any difference and as well I'm running Stacker
	4.0.  This is really frustrating and I need the program for
	my program at school.  Any help would be great.

	-CB

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!galaxy.ucr.edu!library.ucla.edu!europa.eng.gtefsd.com!howland.reston.ans.net!cs.utexas.edu!geraldo.cc.utexas.edu!austin.lockheed.com!not-for-mail
From: mcinroy@austin.lockheed.com (John W. McInroy)
Newsgroups: bionet.software,bionet.population-bio,sci.bio
Subject: Software to track wildlife migration?
Date: 4 Oct 1994 16:43:46 -0500
Organization: Lockheed Austin Division
Lines: 94
Message-ID: <36siai$1jq@antares.Austin.Lockheed.COM>
NNTP-Posting-Host: antares.austin.lockheed.com
Xref: biosci bionet.software:9521 bionet.population-bio:817 sci.bio:11159

Last month I posted the following item:  

: I am looking for software that can be used to 
: track phenomena such as the movement of banded 
: birds or other wildlife.  I would appreciate 
: any information available.  

: I will summarize responses and post them.  

: John McInroy
 [McInroy@Austin.Lockheed.com]

Thanks to all who responded.  As promised, here is a summary of the responses 
that I have received so far:  
-------------------------------------------------------------------------------
From: "Dr Tristram Wyatt, Continuing Education" <wyatt@vax.ox.ac.uk>
. . .
wildtrak is one such programme
you can get details by writing to 
Dr I Todd, Dept of Zoology, univ of oxford, south parks rd, oxford, OX1 3PS, UK

regards
t
-------------------------------------------------------------------------------
From: bss119@thunder ( Mr. R.D.McKay)
Organization: University of Wales, Bangor.

	I'm not sure how applicable it would be, but would one of the
telemetry software packages be of any use?  I believe the US Fish and Game
people have put one out through the University of Idaho called simply Home
Range.

	A better option would be Robert Kenward's program Ranges IV (or
maybe even V by now).  This allows associated variable with fixes, and I
have seen it used to determine home range over time slices.  Kenward works
for the UK Institute of Terrestrial Ecology (ITE).
--
	Valerian.

BSS119@bangor.ac.uk

[from my response:]
Do you happen to have an e-mail address for R. Kenward?

From: "Mr. R.D.McKay" <bss119@clss1.bangor.ac.uk>
. . .
	Sorry, I don't have an e-mail address for the guy.  I'll send you a
postal as soon as I can get my hands on one. . . .
----------------------------------------------------------------------------
From huberr@bkfug.kfunigraz.ac.at  Ukn Oct  4 07:38:32 1994
. . . 
I have written a program for the analysis of homeranges for the Apple
Macintosh. The program is currently in a beta version and will be distributed
as postcard ware. The documentation is still very sketchy, and the software may
still contain a few bugs (actually I am sure it does).

If you are interested then you are more than welcome to give the program a
spin. It accepts ASCII TEXT files containing the X and Y coordinates of
consecutive captures; the coordinates are separated by a tab, captures are
separated by carriage returns - so nothing out of the ordinary. I am working on
recompiling it for the Power PC but have not completed that yet.

You can then use a variety of analyses to estimate homeranges, calculate
activity centers, etc. It also does some contour plots and surface plots of
utilisation distributions.

It would help me greatly to hear of other people applying it to their data sets
and what would come in handy for other users. I intend to publish the program
and its availability later this fall - if all goes well.

So let me know if you are interested. You can access the program and a folder
containing sample documents via FTP from 143.50.28.74 using 'Home' and 'Range'.
Note this is case sensitive.

Hope this is of any help,
Lobsterman		
Robert Huber                                       /\
Snailmail: Karl-Franzens-University Graz          /  \
  Dept. Zoology, Div. Neuroethology            --/----\--
  Universitaetsplatz 2                         |_|____|_|
  A-8010 Graz                                   |  /\  |
  AUSTRIA                                       |  \/  |___
old EMail: Lobsterman@edvz.uni-graz.ada.at      |______/
new Email: Robert.Huber@kfunigraz.ac.at      __/ Grazer
Tel: Austria (316) 380-5281 (office)        /    Uhrturm
		or 380-5604 (lab)
		or 380-5597 (secretary)
Fax: Austria (316) 381-255             
---------------------------------------------------------
|		I can't see Texas from here!		|
|		 and Harvard Square neither  		|
---------------------------------------------------------



From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!rutgers!netnews.upenn.edu!dsinc!ub!acsu.buffalo.edu!ubvms.cc.buffalo.edu!ORBASHU
From: orbashu@ubvms.cc.buffalo.edu
Subject: SSCP analysis/Help
Message-ID: <Cx61qM.4CC@acsu.buffalo.edu>
Sender: nntp@acsu.buffalo.edu
Nntp-Posting-Host: ubvmsa.cc.buffalo.edu
Reply-To: orbashu@ubvms.cc.buffalo.edu
Organization: University at Buffalo
Date: Tue, 4 Oct 1994 20:47:09 GMT
Lines: 1

I don't know if its a FAQ, I am interested in using SSCP to detect single base pair differences.  I have never done SSCP before therefore I am interested in knowing the procedure etc I can follow.  Any suggestions are appreciated. Thanx

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!rutgers!netnews.upenn.edu!dsinc!ub!acsu.buffalo.edu!ubvms.cc.buffalo.edu!ORBASHU
From: orbashu@ubvms.cc.buffalo.edu
Subject: Nucleic acid data base using blast
Message-ID: <Cx61Bp.42K@acsu.buffalo.edu>
Sender: nntp@acsu.buffalo.edu
Nntp-Posting-Host: ubvmsa.cc.buffalo.edu
Reply-To: orbashu@ubvms.cc.buffalo.edu
Organization: University at Buffalo
Date: Tue, 4 Oct 1994 20:38:13 GMT
Lines: 1

I have an accession no. of a gene I am interested in getting the sequence from Genebank using blast server at ncbi.  Could somebody tell me how I can retreive the info? I will appreciate any help. I used to be able to retreive using retreive @genebank... I've lost the info now. Please help

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!swrinde!sgiblab!sgigate.sgi.com!olivea!koriel!lll-winken.llnl.gov!overload.lbl.gov!ames!waikato!canterbury.ac.nz!chmeds.ac.nz!gordon
From: gordon@chmeds.ac.nz
Newsgroups: bionet.software,bionet.general
Subject: Anatomy on a disk?
Message-ID: <1994Oct4.183453.608@chmeds.ac.nz>
Date: 4 Oct 94 18:34:53 +1200
Lines: 16
Xref: biosci bionet.software:9511 bionet.general:11395

I'm looking for an anatomy CDROM - lots of pictures of human anatomy,
software not important as the pictures are going to be used (in a training
setting) to accompany other material. Photorealism is required; good line 
drawings would be an added bonus.

I've seen lots of these written about in the press but now that I need one
I cannot locate any vendors!  Any leads?

Slainte
Gordon
--
Gordon Findlay,  Computer Scientist, Christchurch School of Medicine
                 Nuclear-free New Zealand       !SYSTEM-F-SYSERR: System
Email:  Gordon@CHMEDS.AC.NZ                     !error.  Hit any user to
Paper:  PO Box 4345, Christchurch,  NEW ZEALAND !continue.
Voice:  +64-3-364 0540                          !

From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!usc!howland.reston.ans.net!cs.utexas.edu!convex!news.duke.edu!godot.cc.duq.edu!newsfeed.pitt.edu!dsinc!netnews.upenn.edu!mail1.sas.upenn.edu!smoore
From: smoore@mail1.sas.upenn.edu (Sean David Moore)
Newsgroups: bionet.software
Subject: alignment for windows
Date: 4 Oct 1994 16:58:40 GMT
Organization: University of Pennsylvania
Lines: 26
Message-ID: <36s1k0$647@netnews.upenn.edu>
NNTP-Posting-Host: mail1.sas.upenn.edu
X-Newsreader: TIN [version 1.2 PL2-upenn1.1]

I am looking for an alignment program for DNA and Proteins for Windows.  
We recently revieved GeneRunner, it aligns only blocks...I want to allow 
for Gap-penalties etc.  A nice cheap program will do, Gene Runner does 
the rest.  

I have no association with Gene Runner or Hastings software...merely 
stating a point.

PLease supply me with a source as well.

Thanks in Advance.



--
Sean Moore

VAMC Philadelphia,
Medical College of Pennsylvania,
and the University of Pennsylvania...

.

smoore@sas.upenn.edu



From owner-software@net.bio.net Mon Oct 03 23:00:00 1994
Path: biosci!rutgers!gatech!howland.reston.ans.net!EU.net!sunic!umdac!Peter.Lundberg
From: peterl@umdix.umdc.umu.se (Peter Lundberg)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Date: 4 Oct 1994 17:36:27 GMT
Organization: Phys Chem, University of Umea, Sweden
Lines: 8
Sender: -Not-Authenticated-[2976]
Message-ID: <36s3qr$gse@kitten.umdc.umu.se>
References: <sspencer-260994203725@f181-207.net.wisc.edu> 
 <tan-2809941449410001@smac.ethz.ch> 
 <1994Sep29.181744.29696@genes.icgeb.trieste.it> 
 <1994Oct1.142817.8747@mbcf>  <36rkur$nbj@nyx10.cs.du.edu>
NNTP-Posting-Host: plgmac.chem.umu.se
X-Posted-From: InterNews 1.0@kitten.umdc.umu.se.
Xdisclaimer: No attempt was made to authenticate the sender's name.
Xref: biosci bionet.molbio.methds-reagnts:19193 bionet.software:9518

I vote YES for this suggestion!

73, Peter

==================================
Peter Lundberg
Email: peterl@umdix.umdc.umu.se
============761.91141=============

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!usc!howland.reston.ans.net!swrinde!sgiblab!sgigate.sgi.com!enews.sgi.com!decwrl!netcomsv!ix.netcom.com!netcom.com!weix
From: weix@netcom.com (Patrick Weix)
Subject: Re: Promega on the Internet
Message-ID: <weixCx6JqI.FKE@netcom.com>
Organization: NETCOM On-line Communication Services (408 261-4700 guest)
References: <sspencer-260994203725@f181-207.net.wisc.edu> <tan-2809941449410001@smac.ethz.ch> <1994Sep29.181744.29696@genes.icgeb.trieste.it> <1994Oct1.142817.8747@mbcf> <36rkur$nbj@nyx10.cs.du.edu>
Date: Wed, 5 Oct 1994 03:15:54 GMT
Lines: 28
Xref: biosci bionet.molbio.methds-reagnts:19271 bionet.software:9538

rnusbick@nyx10.cs.du.edu (robert nusbickel) writes:


>This discussion about PROMEGA placing there materials on the net has got 
>me thinking. How's about a service which would be sort of like a directory 
>of all the suppliers information, including ordering information, 
>protocols, and descriptions of the materials, and make this available 
>through the net? It certainly would be advantageous to the suppliers to 
>put their information into one location and it would be great for 
>researchers to have only one place to check on reagents, etc. What do you 
>think?

>Just looking for some opinions.

I tell you, I would much rather grep a database than thumb through
catalog after catalog trying to guess where all my items are listed.
Another plus, will make comparison shopping a snap.

I'm all for it.

Patrick

>Andy Nusbickel
-- 
  "The large print giveth, and the small print taketh away."
 					Tom Waits
 /------------------------------------------------------------\
 | Patrick Weix                        weix@netcom.com        |
 | UT Southwestern Medical Center      weix@utsw.swmed.edu    |
 | 5323 Harry Hines Blvd               tel: (214) 648-5050    |
 | Dallas, TX 75235                    fax: (214) 648-5453    |
 \------------------------------------------------------------/

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!swrinde!cs.utexas.edu!convex!news.duke.edu!godot.cc.duq.edu!newsfeed.pitt.edu!dsinc!ub!galileo.cc.rochester.edu!troi.cc.rochester.edu!mshelly
From: mshelly@troi.cc.rochester.edu (Mark A. Shelly)
Subject: EIA (ELISA) software
Message-ID: <1994Oct5.134136.20645@galileo.cc.rochester.edu>
Keywords: Elisa, EIA
Sender: news@galileo.cc.rochester.edu
Nntp-Posting-Host: troi.cc.rochester.edu
Organization: University of Rochester - Rochester, New York
Date: Wed, 5 Oct 94 13:41:36 GMT
Lines: 17

Simple question:

I'm looking for options for EIA or ELISA software to assist in analysis of 
these assays. Should include robust analysis options, along with import and
export options. 

We're considering Macintosh, DOS, and Windows solutions. Is anything
cross-platform compatible?

Thanks in advance,

Mark Shelly, M.D.
University of Rochester
mshelly@medicine.rochester.edu
(716)461-6821



From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!rutgers!gatech!howland.reston.ans.net!cs.utexas.edu!convex!news.duke.edu!usenet
From: Sheetz Lab
Newsgroups: bionet.software
Subject: Re: Promega on the Internet
Date: 5 Oct 1994 21:31:12 GMT
Organization: Duke University Medical Center
Lines: 33
Distribution: world
Message-ID: <36v5v0$ese@news.duke.edu>
References: <sspencer-260994203725@f181-207.net.wisc.edu>
NNTP-Posting-Host: sizzle.cellbio.duke.edu

In article <sspencer-260994203725@f181-207.net.wisc.edu>
sspencer@rhino.bocklabs.wisc.edu (Stephan Spencer) writes:
>I (and Promega) would like to know who out there would like to see Promega
>on the World Wide Web, and what you would like to see (catalog, technical
>notes, online ordering, tech support, etc...)
>
>Second question.. would you use their services online? Would you order
>online?
>
>If enough people respond positively, I think Promega execs will be
>convinced to  make themselves available on the Info Superhighway. Right now
>they are sceptical that researchers will want to order online...
It's a great idea to include on-line catalog as well as the tech info.. USB
used to distribute their very informative catalogs on disk (before join with
Amersham). Promega also distributed their beautiful protocols etc in meetings.
Tech support like NEB's will certainly help everyone.
 
As for ordering, most institutions are restricted by their ordering department.
So far, we have been getting around it by 1) getting a standing PO and 2)
getting a regular PO if your ordering department allow you to order over the
phone by yourself. Once you have a PO issued (regular or standing), you can
fax/phone/mail/e-mail, in most instances. I have been using Sigma's Sigma
Direct for most orders from SIgma, and Genset for Oligos ordering for the last
couple of years. It 's  wonderful to order this way since we can send in orders
anytime of the day/week and keep a copy of our orders. It would be better if
Sigma Direct can be accessed via internet instead by Modem.
Anyhow, as more of us push the ordering department by partially bypassing them
like this, they begin to learn to change and enter the modern world. Recently,
the Duke system gave up their archaic way of requiring a written requisition
handed in person and we can now request a PO by sending in an e-mail to them
and get it the second day.
Good luck with the rest of you and let's push them!
Hanry Yu.

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!jobone!heifetz.msen.com!zib-berlin.de!fauern!lrz-muenchen.de!news.informatik.uni-muenchen.de!wap18.zi.biologie.uni-muenchen.de!salger
From: salger@wap18.zi.biologie.uni-muenchen.de (Klaus Salger)
Newsgroups: bionet.software
Subject: Re: alignment for windows
Date: 5 Oct 1994 23:19:49 GMT
Organization: Institut fuer Informatik der Universitaet Muenchen
Lines: 40
Distribution: world
Message-ID: <36vcal$8pl@arcadia.informatik.uni-muenchen.de>
References: <36s1k0$647@netnews.upenn.edu> <36ukh8$5nj@news.doit.wisc.edu>
NNTP-Posting-Host: wap18.zi.biologie.uni-muenchen.de
X-Newsreader: TIN [version 1.2 PL2]

lehn@facstaff.wisc.edu wrote:

: In article <36s1k0$647@netnews.upenn.edu>, <smoore@mail1.sas.upenn.edu> writes:
: > Path: 
: news.doit.wisc.edu!saimiri.primate.wisc.edu!sdd.hp.com!spool.mu.edu!howland.reston.
: ans.net!cs.utexas.edu!convex!news.duke.edu!godot.cc.duq.edu!newsfeed.pitt.edu!dsinc
: !netnews.upenn.edu!mail1.sas.upenn.edu!smoore

: > I am looking for an alignment program for DNA and Proteins for Windows.  
: > We recently revieved GeneRunner, it aligns only blocks...I want to allow 
: > for Gap-penalties etc.  A nice cheap program will do, Gene Runner does 
: > the rest.  
: > 

: > --
: > Sean Moore

: Try MACAW, its a great program avaliable by anonymous FTP 
: from NCBI at:

: ncbi.nlm.nih.gov

: Its avaliable in both a Windows and Mac version.

As far as I know MACAW does also align only blocks - no global alignments
(with gap penalties etc.).
The DOS-version of ClustalV would do the job (there is no Windows-version).
  Klaus


Klaus Salger
Zoologisches Institut
AG MacWilliams
Luisenstr. 14
80333 Muenchen
Germany

phone : ++49 (0)89 5902 -502
FAX   :                 -450
e-mail: salger@zi.biologie.uni-muenchen.de

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!fconvx.ncifcrf.gov!fcsparc6!pnh
From: pnh@fcsparc6.ncifcrf.gov (Paul N Hengen)
Subject: Re: Promega on the Internet
Message-ID: <Cx7ozq.A8q@ncifcrf.gov>
Summary: Technical support
Sender: Paul N. Hengen
Nntp-Posting-Host: fcsparc6.ncifcrf.gov
Organization: Frederick Cancer Research and Development Center
References: <sspencer-260994203725@f181-207.net.wisc.edu>
Date: Wed, 5 Oct 1994 18:07:01 GMT
Lines: 21
Xref: biosci bionet.molbio.methds-reagnts:19250 bionet.software:9534

Stephan Spencer (sspencer@rhino.bocklabs.wisc.edu) wrote:

: I (and Promega) would like to know who out there would like to see Promega
: on the World Wide Web, and what you would like to see (catalog, technical
: notes, online ordering, tech support, etc...)

That Promega is interested in providing technical support on the WWW is quite
a switch form their usual policies. When I asked Promega why they read
methds-reagnts and do not respond to people having trouble with their products,
the answer I got was "We don't think it's appropriate to help people on the
net. They should call instead". I would definitely like to see technical support,
but I doubt we'll get any more than advertisements on WWW. Thanks, but no thanks.

*******************************************************************************
* Paul N. Hengen, Ph.D.                           /--------------------------/*
* National Cancer Institute                       |Internet: pnh@ncifcrf.gov |*
* Laboratory of Mathematical Biology              |   Phone: (301) 846-5581  |*
* Frederick Cancer Research and Development Center|     FAX: (301) 846-5598  |*
* Frederick, Maryland 21702-1201 USA              /--------------------------/*
* - -  Methods FAQ list -> http://fconvx.ncifcrf.gov:2001/~pnh/info.html  - - *
*******************************************************************************

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!COMPBIO2.MED.WAYNE.EDU!steve
From: steve@COMPBIO2.MED.WAYNE.EDU (Stephen Krawetz)
Newsgroups: bionet.software
Subject: Image composition software for SUN Solaris 2.3
Date: 5 Oct 1994 11:46:49 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 16
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9410051847.AA00713@compbio3.med.wayne.edu>
NNTP-Posting-Host: net.bio.net



I am looking for some software that will run on a SUN under SOLARIS 2.3
for basic image processing to prepare images for publications.  I would 
the program to set up an 8.5 x 11 page upon which I can place and change
the multiple objects.

What I need is cut + paste  
Label
stretch
background corrections
box and line drawing
and a few symbols as well as various character sets.

Is there anything like that out their.  Freeware or Shareware if possible.  


From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!rutgers!csn!carbon!saimiri.primate.wisc.edu!news.doit.wisc.edu!news
From: lehn@facstaff.wisc.edu
Newsgroups: bionet.software
Subject: Re: alignment for windows
Date: Wed, 05 Oct 94 11:25:28 EDT
Organization: Division of Information Technology
Lines: 23
Message-ID: <36ukh8$5nj@news.doit.wisc.edu>
References: <36s1k0$647@netnews.upenn.edu>
NNTP-Posting-Host: islet.medsch.wisc.edu
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=US-ASCII
X-Newsreader: NEWTNews & Chameleon -- TCP/IP for MS Windows from NetManage


In article <36s1k0$647@netnews.upenn.edu>, <smoore@mail1.sas.upenn.edu> writes:
> Path: 
news.doit.wisc.edu!saimiri.primate.wisc.edu!sdd.hp.com!spool.mu.edu!howland.reston.
ans.net!cs.utexas.edu!convex!news.duke.edu!godot.cc.duq.edu!newsfeed.pitt.edu!dsinc
!netnews.upenn.edu!mail1.sas.upenn.edu!smoore

> I am looking for an alignment program for DNA and Proteins for Windows.  
> We recently revieved GeneRunner, it aligns only blocks...I want to allow 
> for Gap-penalties etc.  A nice cheap program will do, Gene Runner does 
> the rest.  
> 

> --
> Sean Moore

Try MACAW, its a great program avaliable by anonymous FTP 
from NCBI at:

ncbi.nlm.nih.gov

Its avaliable in both a Windows and Mac version.


From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!rutgers!netnews.upenn.edu!ccat.sas.upenn.edu!aaron
From: aaron@ccat.sas.upenn.edu (Aaron Pawlyk)
Newsgroups: bionet.software
Subject: Test
Date: 5 Oct 1994 18:06:45 GMT
Organization: University of Pennsylvania
Lines: 2
Message-ID: <36upvl$8ts@netnews.upenn.edu>
NNTP-Posting-Host: ccat.sas.upenn.edu
X-Newsreader: Tin 1.1 PL4

This is a test


From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!daresbury!not-for-mail
From: 2020221%LAVALVX1.earn@earn-relay.ac.uk
Newsgroups: bionet.software
Subject: signoff
Date: 5 Oct 1994 20:44:04 +0100
Lines: 1
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <36uvm4$2ti@mserv1.dl.ac.uk>
Original-To: bio-software@DL.AC.UK

signoff bionet-news Robert J. Bojanowski

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!rutgers!gatech!newsxfer.itd.umich.edu!jobone!heifetz.msen.com!zib-berlin.de!informatik.tu-muenchen.de!lrz-muenchen.de!news.informatik.uni-muenchen.de!wap18.zi.biologie.uni-muenchen.de!salger
From: salger@wap18.zi.biologie.uni-muenchen.de (Klaus Salger)
Newsgroups: bionet.software
Subject: Re: Commercial Windows Sequence-Handling Software...
Date: 5 Oct 1994 17:04:13 GMT
Organization: Institut fuer Informatik der Universitaet Muenchen
Lines: 29
Distribution: world
Message-ID: <36umad$3ge@arcadia.informatik.uni-muenchen.de>
References: <ed.61.000B1012@molbiol.uct.ac.za>
NNTP-Posting-Host: wap18.zi.biologie.uni-muenchen.de
X-Newsreader: TIN [version 1.2 PL2]

Ed Rybicki (ed@molbiol.uct.ac.za) wrote:
: Does anyone know of a commercial package running under Windows 3.1x, which can:
: 1) handle nucleotide sequence data (eg: generate restriction maps, translate 
: in all ORFs, highlight);
: 2) design PCR primers
: 3) etc?

: I downloaded a demo of one a while back, and it looked wondeful, and now I 
: can't find it again or remember what it was!  Anyone have any idea?

: Thanks,

Ed, this wonderful program might have been VectorNT. It can handel sequences,
Primers and a lot of other things. The demo version is available on
ftp.bio.indiana.edu/molbio/ibmpc/vntd-demo.exe.
(I have no affiliation with Informax...)
  Klaus


Klaus Salger
Zoologisches Institut
AG MacWilliams
Luisenstr. 14
80333 Muenchen
Germany

phone : ++49 (0)89 5902 -502
FAX   :                 -450
e-mail: salger@zi.biologie.uni-muenchen.de

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!quagga.ru.ac.za!inet.up.ac.za!news
From: root@biochem.up.ac.za (Fourie Joubert)
Newsgroups: bionet.software
Subject: Image processing for Solaris?
Date: 5 Oct 1994 08:46:45 GMT
Organization: University of Pretoria
Lines: 15
Message-ID: <36tp5l$bek@inet.up.ac.za>
Reply-To: fourie@ccnet.up.ac.za
NNTP-Posting-Host: biochem.up.ac.za

Hi

Does anyone know of a public domain image analysis package that will
compile under Solaris? I tried ALV and DNAGUI but couldn't get them
compiled under Solaris 2.3.

Any help would be sincerely appreciated!

---
Fourie Joubert
Department of Biochemistry
University of Pretoria
fourie@ccnet.up.ac.za
+27-12-420-2011


From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Re: mosaic
Message-ID: <1994Oct5.123704.13891@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
References: <36u30i$bpr@mserv1.dl.ac.uk>
Distribution: bionet
Date: Wed, 5 Oct 1994 12:37:04 GMT
Lines: 22

suter@VAX.MPIZ-KOELN.MPG.d400.de wrote:

: where can i get get I fwhere can i
: mosaic software ? 

How to get Mosaic, what to expect, and more? We are aware of the need to 
provide training... Watch bionet.software.www for the WWW introduction 
course, starting Monday Oct 10, 1994!  The course will be done by F.Eggen-
berger as part of EMBnet Switzerland Services. 


Regards
Reinhard Doelz
EMBnet Switzerland 



-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!newshost.lanl.gov!.lanl.gov!kvr
From: kvr@.lanl.gov (Ken Van Riper)
Newsgroups: bionet.software
Subject: Looking for Human Models
Date: 5 Oct 1994 12:56:17 GMT
Organization: Los Alamos National Laboratory
Lines: 12
Distribution: world
Message-ID: <36u7ph$hs@newshost.lanl.gov>
NNTP-Posting-Host: u2.lanl.gov
Keywords: phantom

I am looking for computer models of humans (of all
ages, size, and sexes) for use in Monte Carlo 
simulations of radiation diagnostics and therapy.
For efficient Monte Carlo simulations, we require 
models constructed of quadratic surfaces (planes, spheres,
cylinders, ellipsiods, elliptical cylinders, ...)

Any leads would be appreciated, as would direct reply
by email.

Ken Van Riper                  kvr@lanl.gov
Radiation Transport Group,  Los Alamos National Laboratory

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!uknet!daresbury!not-for-mail
From: suter@VAX.MPIZ-KOELN.MPG.d400.de
Newsgroups: bionet.software
Subject: mosaic
Date: 5 Oct 1994 12:34:42 +0100
Lines: 10
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <36u30i$bpr@mserv1.dl.ac.uk>
Original-To: bio-software@dl.ac.uk


hi,
where can i get get I fwhere can i




mosaic software ? 

clemens

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!usc!howland.reston.ans.net!quagga.ru.ac.za!ucthpx!uctvax.uct.ac.za!pc24.mic.uct.ac.za!ed
Newsgroups: bionet.software
Subject: Commercial Windows Sequence-Handling Software...
Message-ID: <ed.61.000B1012@molbiol.uct.ac.za>
From: ed@molbiol.uct.ac.za (Ed Rybicki)
Date: Wed, 5 Oct 1994 11:39:52 UNDEFINED
Distribution: world
Organization: Microbiology Dept., Univ. Cape Town
Keywords: Windows, sequence
Nntp-Posting-Host: pc24.mic.uct.ac.za
X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #1]
Lines: 27

Does anyone know of a commercial package running under Windows 3.1x, which can:
1) handle nucleotide sequence data (eg: generate restriction maps, translate 
in all ORFs, highlight);
2) design PCR primers
3) etc?

I downloaded a demo of one a while back, and it looked wondeful, and now I 
can't find it again or remember what it was!  Anyone have any idea?

Thanks,


  ___________________________________________________________________
 | Ed Rybicki, PhD             |       "Lord, won't you buy me       |
 | (ed@molbiol.uct.ac.za)      |                                     |
 | Dept Microbiology           |         A Mer-ce-des Benz..."       |
 | University of Cape Town     |                                     |
 | Private Bag, Rondebosch     |   "My friends all drive Porsches    |
 | 7700, South Africa          |                                     |
 | fax: 27-21-650 4023         |         I must make amends..."      |
 | phone: 650-3265             |     (Janis Joplin, Pearl, 1971)     |
  --------------------------------------------------------------------






From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!rutgers!gatech!newsxfer.itd.umich.edu!jobone!heifetz.msen.com!zib-berlin.de!informatik.tu-muenchen.de!lrz-muenchen.de!news.informatik.uni-muenchen.de!wap18.zi.biologie.uni-muenchen.de!salger
From: salger@wap18.zi.biologie.uni-muenchen.de (Klaus Salger)
Newsgroups: bionet.software
Subject: Re: Nucleic acid data base using blast
Date: 5 Oct 1994 17:23:08 GMT
Organization: Institut fuer Informatik der Universitaet Muenchen
Lines: 23
Distribution: world
Message-ID: <36unds$3ge@arcadia.informatik.uni-muenchen.de>
References: <Cx61Bp.42K@acsu.buffalo.edu>
NNTP-Posting-Host: wap18.zi.biologie.uni-muenchen.de
X-Newsreader: TIN [version 1.2 PL2]

orbashu@ubvms.cc.buffalo.edu wrote:
: I have an accession no. of a gene I am interested in getting the sequence
: from Genebank using blast server at ncbi.  Could somebody tell me how I
: can retreive the info? I will appreciate any help. I used to be able to
: retreive using retreive @genebank... I've lost the info now. Please help

You could also get the genbank entry (fast) by gophering to
"fly.bio.indiana.edu/77/.indices/genbank".
This is a seachable gopher index which will find not only the accession
number but also the gene's name.
  Klaus


Klaus Salger
Zoologisches Institut
AG MacWilliams
Luisenstr. 14
80333 Muenchen
Germany

phone : ++49 (0)89 5902 -502
FAX   :                 -450
e-mail: salger@zi.biologie.uni-muenchen.de

From owner-software@net.bio.net Tue Oct 04 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!news.mic.ucla.edu!steve3.mbi.ucla.edu!rkagan
From: Ron Kagan <rkagan@ewald.mbi.ucla.edu>
Newsgroups: bionet.software
Subject: Re: Nucleic acid data base using blast
Date: 5 Oct 1994 00:21:16 GMT
Organization: Dept. of Chemistry and Biochemistry, ULCA
Lines: 29
Distribution: world
Message-ID: <36srhs$oln@news.mic.ucla.edu>
References: <Cx61Bp.42K@acsu.buffalo.edu>
NNTP-Posting-Host: steve3.mbi.ucla.edu
X-UserAgent: Nuntius v1.1.2
X-XXMessage-ID: <AAB7404A3D0127D5@steve3.mbi.ucla.edu>
X-XXDate: Tue, 4 Oct 94 17:24:26 GMT

In article <Cx61Bp.42K@acsu.buffalo.edu> , orbashu@ubvms.cc.buffalo.edu
writes:
>I have an accession no. of a gene I am interested in getting the
sequence from 
>Genebank using blast server at ncbi.  Could somebody tell me how I can
retreive 
>the info? I will appreciate any help. I used to be able to retreive
using 
>retreive @genebank... I've lost the info now. Please help

Send a message to:  retrieve@ncbi.nlm.nih.edu

Specify in the body of the message:

DATALIB gb
BEGIN
<your accession no. or keyword here>



Ron Kagan

**********************************************************************
"My Kindness is not random, and nothing senseless was ever beautiful."

                                                 - J. Zabriskie
**********************************************************************
Ron Kagan
rkagan@ewald.mbi.ucla.edu

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!galaxy.ucr.edu!library.ucla.edu!europa.eng.gtefsd.com!howland.reston.ans.net!vixen.cso.uiuc.edu!ruger-5.slip.uiuc.edu!user
From: r-larkin@uiuc.edu (Ron Larkin)
Newsgroups: bionet.software,bionet.population-bio,sci.bio
Subject: Re: Software to track wildlife migration?
Date: Wed, 05 Oct 1994 20:58:25 -0600
Organization: Illinois Natural History Survey
Lines: 23
Message-ID: <r-larkin-0510942058250001@ruger-5.slip.uiuc.edu>
References: <36siai$1jq@antares.Austin.Lockheed.COM>
NNTP-Posting-Host: ruger-5.slip.uiuc.edu
Xref: biosci bionet.software:9539 bionet.population-bio:827 sci.bio:11185

In article <36siai$1jq@antares.Austin.Lockheed.COM>,
mcinroy@austin.lockheed.com (John W. McInroy) wrote:
> Last month I posted the following item:  
> : I am looking for software that can be used to 
> : track phenomena such as the movement of banded 
> : birds or other wildlife.  I would appreciate 
> : any information available.  

John,
  Having missed the original post, I don't see much direct connection
between "wildlife migration", banding data, and the home range analysis
programs listed in your summary posting.
  Nevertheless, you may be interested in a review article on home range
software that appears in the summer '94 Wildlife Society Bulletin.  It
reviews about a dozen packages that run on PC's.  I can send you a reprint
if you like.

Regards,
Ron Larkin
Illinois Natural History Survey
r-larkin@uiuc.edu

PS  Is Lockheed applying its technology and muscle to wildlife matters???

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!Austria.EU.net!newsfeed.ACO.net!swidir.switch.ch!scsing.switch.ch!yogi!bioftp.unibas.ch!doelz
Newsgroups: bionet.software
Subject: Remember the data... Re: Can XXXXXX replace YYY package? Or almost??
Message-ID: <1994Oct6.105608.13879@comp.bioz.unibas.ch>
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Date: Thu, 6 Oct 1994 10:56:08 GMT
References: <36vkk9$gtq@mace.cc.purdue.edu>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
Lines: 32

Xiaomu Niu (xniu@mace.cc.purdue.edu) wrote:

: 	But here is the question: (sorry for the long introduction)
: Can XXXXXX replace YYY completely or nearly? What about speed? It
: seems we have people here running XXXXXX on a Mac SE with a CD-ROM
: happily. If we understand right, ZZZ covers most of YYY's functions,
: and it's available for free.

Without getting involved in judging user interface and affodability, 
keep in mind that a central installation ought to provide up-to-date 
data in its literal meaning (weekly, for example). You will possibly 
have a hard time to get this into PC/Mac based products. Sure you can 
paint your restriction maps as nice as you want with any software, but 
as soon as external data sets (databases) are involved a centralized, 
up-to-date facility is unaviodable. And, Training is usually cheaper 
as better resources (including the net) will cope. Last, complexity 
and continuity are items which have a high rating in customer's view, 
so be careful in moving to another technology unless you made sure that
people can move their data, results, and procedures easily.  

Regards
Reinhard Doelz





-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!spool.mu.edu!news.nd.edu!glambertimac.bio.nd.edu!user
From: William.L.Perry.13@nd.edu (William.L.Perry)
Newsgroups: bionet.software
Subject: PAUP...Where to get
Date: 6 Oct 1994 12:52:36 GMT
Organization: University of Notre Dame
Lines: 3
Message-ID: <William.L.Perry.13-0610940753090001@glambertimac.bio.nd.edu>
NNTP-Posting-Host: glambertimac.bio.nd.edu

Hi, I am looking for the program by Swofford called PAUP.  I need to
install it for an upcoming class project.  Any pointers on addresses to
swofford or FTP sites would be greatly appreciated

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!cs.utexas.edu!convex!convex!constellation!news.uoknor.edu!aardvark.ucs.uoknor.edu!jwickham
From: jwickham@aardvark.ucs.uoknor.edu (WICKHAM,JOHN)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Date: 5 Oct 1994 23:08 CDT
Organization: University of Oklahoma - University Computing Services
Lines: 24
Distribution: world
Message-ID: <5OCT199423082068@aardvark.ucs.uoknor.edu>
References: <sspencer-260994203725@f181-207.net.wisc.edu> <tan-2809941449410001@smac.ethz.ch> <36rkur$nbj@nyx10.cs.du.edu>
NNTP-Posting-Host: 129.15.10.11
News-Software: VAX/VMS VNEWS 1.41    
Xref: biosci bionet.molbio.methds-reagnts:19282 bionet.software:9541

In article <36rkur$nbj@nyx10.cs.du.edu>, rnusbick@nyx10.cs.du.edu (robert nusbickel) writes...
>This discussion about PROMEGA placing there materials on the net has got 
>me thinking. How's about a service which would be sort of like a directory 
>of all the suppliers information, including ordering information, 
>protocols, and descriptions of the materials, and make this available 
>through the net? It certainly would be advantageous to the suppliers to 
>put their information into one location and it would be great for 
>researchers to have only one place to check on reagents, etc. What do you 
>think?
> 
>Just looking for some opinions.
> 
> 
>Andy Nusbickel

Invitrogen now offers plasmid sequences via internet. I've also e-mailed to 
Stratagene to obtain similair information. Product databases could be very
useful, especially when technical help via AT&Tnet can be slow and/or difficult
to obtain.

Although, I certainly don't want Biotech reps responding to questions with the
sole intention of selling a product...

Quyen Wickham

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!europa.eng.gtefsd.com!news.umbc.edu!haven.umd.edu!purdue!mozo.cc.purdue.edu!not-for-mail
From: xniu@mace.cc.purdue.edu (Xiaomu Niu)
Newsgroups: bionet.software
Subject: Can DNAsis replace GCG package? Or almost??
Date: 5 Oct 1994 20:41:29 -0500
Organization: Purdue University
Lines: 37
Message-ID: <36vkk9$gtq@mace.cc.purdue.edu>
NNTP-Posting-Host: mace.cc.purdue.edu

	Please pardon my lack of knowledge in this subject, but we
are trying to decide what kind of sequence analysis package (hardware
and software) to purchase.  We've been spending about $1000 per year
using the GCG package provided by a computing center here on Purdue
campus, and since we project more usage in the future, we decided
that it's time to have our own.

	After a brief search of faq's and archived postings, as well
as talking with collegues here, it seems to us that GCG is beyond
our reach: we don't wish to buy highend workstations. We want a program
or a set of programs with most if not all of the functions provided
by GCG, but with a nicer interface (we've been using line mode for
our GCG here by telnet).

	We narrowed our choices down to two:
		(1) a 486/586 pc running linux and X-windows
		(2) a Machintosh or a Power Mac

	With the first one, we can run MS-Windows with Hitachi's
DNAsis for window, or we install Linux and run GDE plus other freely
availabe sequence analysis programs for unix, something like BIRCH 
(but running on a pc).

	With the second choice, we probably have to purchase the    
MacDNAsis from Hitachi. Or we can try GeneWorks (?) also.

	But here is the question: (sorry for the long introduction)
Can DNAsis replace GCG completely or nearly? What about speed? It
seems we have people here running DNAsis on a Mac SE with a CD-ROM
happily. If we understand right, GDE covers most of GCG's functions,
and it's available for free.

	Please respond to this account or post here. If there is 
enough interest, I'll glad to post a summary.  Thank you in advance.

Xiaomu


From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!bcm!cs.utexas.edu!convex!news.duke.edu!news-feed-1.peachnet.edu!umn.edu!lenti.med.umn.edu!nrd
From: nrd@lenti.med.umn.edu (Neal Dalton)
Subject: Re: mosaic
Message-ID: <Cx9C0L.2z@news.cis.umn.edu>
Sender: news@news.cis.umn.edu (Usenet News Administration)
Nntp-Posting-Host: lenti.med.umn.edu
Organization: University of Minnesota, Twin Cities
X-Newsreader: TIN [version 1.2 PL2]
References: <36u30i$bpr@mserv1.dl.ac.uk>
Distribution: bionet
Date: Thu, 6 Oct 1994 15:17:53 GMT
Lines: 17

suter@VAX.MPIZ-KOELN.MPG.d400.de wrote:

: where can i get get I fwhere can i
: mosaic software ? 

ftp.ncsa.uiuc.edu in /Mosaic/...

For windows try:
   WinWeb (ftp://ftp.einet.net/einet/pc/winweb.zip) or
   Cello  (ftp://fatty.law.cornell.edu/pub/LII/Cello/cello.zip)

People seem to perfer WinWeb.

There is also a macweb or something, but Mosaic seem to work OK on a
MAC.  Unlike windows, which is a problem in itself.

Neal

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!cs.utexas.edu!uunet!zib-berlin.de!informatik.tu-muenchen.de!lrz-muenchen.de!ipp-garching.mpg.de!alf.biochem.mpg.de!krasel
From: krasel@alf.biochem.mpg.de (Cornelius Krasel)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Followup-To: bionet.molbio.methds-reagnts,bionet.software
Date: 6 Oct 1994 15:31:50 GMT
Organization: Rechenzentrum der Max-Planck-Gesellschaft in Garching
Lines: 12
Distribution: world
Message-ID: <371596INNhbt@sat.ipp-garching.mpg.de>
References: <5OCT199423082068@aardvark.ucs.uoknor.edu>
NNTP-Posting-Host: alf.biochem.mpg.de
X-Newsreader: TIN [version 1.1 PL8]
Xref: biosci bionet.molbio.methds-reagnts:19297 bionet.software:9549

WICKHAM,JOHN (jwickham@aardvark.ucs.uoknor.edu) wrote:
: Invitrogen now offers plasmid sequences via internet. 

Could you go into some detail? (Which kind of service (WWW, gopher, ftp),
which address?)

--Cornelius.

--
/* Cornelius Krasel, Abt. Lohse, Genzentrum, D-82152 Martinsried, Germany */
/* email: krasel@alf.biochem.mpg.de                 fax: +49 89 8578 3795 */
/* "People are DNA's way of making more DNA." (Edward O. Wilson, 1975)    */

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!library.ucla.edu!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!news.itd.umich.edu!um.cc.umich.edu!schlyer
From: schlyer@um.cc.umich.edu (B. Schlyer)
Newsgroups: bionet.software
Subject: XY->digital
Date: Thu, 6 Oct 1994 11:08:07
Organization: University of Michigan
Lines: 9
Message-ID: <schlyer.44.000B2303@um.cc.umich.edu>
NNTP-Posting-Host: 141.211.127.155
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

Help.
I'm looking for a program to digitize XY data from a strip chart recorder 
following scanning it into something like a bitmap image.  I know of a 
commercial product, UN-PLOT-IT, I believe, from a Utah company however I would 
like to know if there is shareware or public domain software available.  
Thanks in advance.

schlyer@um.cc.umich.edu


From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
From: Duncan@genesys.demon.co.uk (Duncan Clark)
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!demon!genesys.demon.co.uk!Duncan
Subject: Which Mac for NIH Image?
Distribution: world
Organization: GeneSys Ltd.
Reply-To: Duncan@genesys.demon.co.uk
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Lines:  20
Date: Thu, 6 Oct 1994 14:36:01 +0000
Message-ID: <106303186wnr@genesys.demon.co.uk>
Sender: usenet@demon.co.uk

Hi Folks,

I'd like to use NIH image but have only 486 PC's. I therefore need a 
Mac. I already capture images to the PC and can output an image in a 
format readable by NIH Image. The Mac would be used solely for NIH 
Image and will be used relatively infrequently and processing speed 
isn't high on priorities. Use would be by one or two people only. So
which Mac? What is the minimum configuration that Image requires 
without taking O/N to do the simplest of tasks?

many thanks

Duncan 

-----------------------------------------------------------------------------
Duncan Clark                        | Internet:    duncan@genesys.demon.co.uk
G4ELJ                               | Compuserve:  100015.1406@compuserve.com
-----------------------------------------------------------------------------


From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!daresbury!not-for-mail
From: worm@dsa.mpi-muelheim.mpg.de (Karl-Heinz Worm)
Newsgroups: bionet.software
Subject: Re: mosaic
Date: 6 Oct 1994 15:33:43 +0100
Lines: 15
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <3711s7$qt9@mserv1.dl.ac.uk>
Original-To: bio-soft@dl.ac.uk

doelz@comp.bioz.unibas.ch (Reinhard Doelz) wrote:

>How to get Mosaic, what to expect, and more? We are aware of the need to
>provide training... Watch bionet.software.www for the WWW introduction
>course, starting Monday Oct 10, 1994!  The course will be done by F.Eggen-
>berger as part of EMBnet Switzerland Services.
>


Sorry about the following question but how/where can I watch
bionet.software.www? Hope its not too stupid.

Karl



From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!agate!howland.reston.ans.net!vixen.cso.uiuc.edu!uchinews!quads!ecec
From: ecec@quads.uchicago.edu (Eric Cabot)
Subject: Re: SSCP analysis/Help
Message-ID: <1994Oct6.132707.8853@midway.uchicago.edu>
Followup-To: bionet.methods-reagents 
Sender: news@uchinews.uchicago.edu (News System)
Reply-To: ecec@midway.uchicago.edu
Organization: University of Chicago
References: <Cx61qM.4CC@acsu.buffalo.edu>
Date: Thu, 6 Oct 1994 13:27:07 GMT
Lines: 46

You ask about SSCP analysis. I wonder why you ask it here
rather than in the methods newgroup-to which I am redirecting
follow-ups. 

The basic SSCP procedure is pretty simple. The way I do it
(See Genetics 137:175-188) is as follows:
      
-Perform your PCR with  a little bit of 32P labelled nucleotide included.
 You can cut your PCR reaction volume down to 5 or 10 ul since you         
  probably won't need much product. 

-Heat 1-3 ul of your PCR product together with 9 ul of denaturing
  buffer at 94 C for 2-3 min. (denat. buffer is 95% formamide, 10mM NaOH,
  0.5% bromphenol blue, 0.5% xylene cyanol; this is equivalent to 
  the left over stop solution from an otherwise exhausted sequencing kit).

-Chill on ice immediately for at least 5 minutes prior to electrophoresis
 of the entire preparation on a polyacrylamide gel under non-denaturing 
  condditions.  Don't let your gel get to hot! If you want to run it
  quickly, then run it in a cold-room.  You sometimes  have to play around
   a bit with the concentration of acrylamide and the degree of cross-linking
  but straight out of the bottle gels for proteins should work fine for
  a first approximation.

-Dry the gel onto a piece of 3mm chromatography paper and autoradiograph it.


Alternates:
  -Instead of using 32P you can simply silver stain  the gel. I originally 
   used silver staining myself, but found that others in our lab tended to
   overexpose their gels (irreversibly), apparently out of "greed".

 -If your PCR product is rather long, you might want to cut 5-8 ul with
  an appropriate restriction enzyme in a 10 ul reaction volume, 
  and then use 1-3 ul of that in the denaturation step.

Needless to say, but I'll say it anyway, make sure to include both positive
 and negative controls. If you have some alleles that you know differ by
 a single base pair, then try them out first. It is also instructive to
 run undenatured vs. denatured samples on the gel until you get used to
 the technique-which shouldn't take long.

-Eric Cabot
 

-

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!sun4nl!news.nic.surfnet.nl!mira.sara.nl!VM1.SARA.NL!A428ENDE
From: A428ENDE@VM1.SARA.NL
Newsgroups: bionet.software
Subject: Re: Can DNAsis replace GCG package? Or almost??
Date: Thu, 06 Oct 94 09:28:04 CET
Organization: S.A.R.A. Academic Computing Services Amsterdam
Lines: 45
Message-ID: <17047852A.A428ENDE@VM1.SARA.NL>
References: <36vkk9$gtq@mace.cc.purdue.edu>
NNTP-Posting-Host: vm1.sara.nl
X-Newsreader: NNR/VM S_1.3.2

In article <36vkk9$gtq@mace.cc.purdue.edu>
xniu@mace.cc.purdue.edu (Xiaomu Niu) writes:
 
>        We narrowed our choices down to two:
>                (1) a 486/586 pc running linux and X-windows
>                (2) a Machintosh or a Power Mac
>
>        With the first one, we can run MS-Windows with Hitachi's
>DNAsis for window, or we install Linux and run GDE plus other freely
>availabe sequence analysis programs for unix, something like BIRCH
>(but running on a pc).
 
Although we bought DNAsis on a Mac, I still believe that we made the wrong dess
ision. With a 586 (which is much cheaper than a PowerMac 8100) you can indeed r
un linux and take advantage of all the software available in the Unix environme
nt and you have a very fast PC with all the advantages and programs in this env
ironment (there are also a lot of Public domain and Shareware available).
 
>        With the second choice, we probably have to purchase the
>MacDNAsis from Hitachi. Or we can try GeneWorks (?) also.
>
>        But here is the question: (sorry for the long introduction)
>Can DNAsis replace GCG completely or nearly? What about speed? It
>seems we have people here running DNAsis on a Mac SE with a CD-ROM
>happily. If we understand right, GDE covers most of GCG's functions,
>and it's available for free.
 
Don't buy the Hitachi MacDNAsis! It is full of bugs and strange things. For exa
mple sometimes you can use small letters in your sequence (handy if you are alm
ost sure that this is the base you read) but it converts them randomly to upper
case. In the contig manager it has a very strange way of aligning the sequences
 and sometimes ruin your files by introducing hyphens (it can do it in the mult
iple but it does it also in your sequences!). Complement, reverse and reverse +
complement are not what you expect and so on. It has no ways to format the outp
ut of all the operations so everything must be done in a drawing program or tex
t editor. And I feel that I don't have all the possibilities which were impleme
nted in GCG (for example blast). Does someone have the email number of Hitachi,
 because they are very hard to reach from Europe.
 
>        Please respond to this account or post here. If there is
>enough interest, I'll glad to post a summary.  Thank you in advance.
 
Please do. May be we can also invest in something better.
Henk van de Kamer
CHLAMY@SARA.NL

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!bcm!cs.utexas.edu!uunet!news.pipeline.com!malgudi.oar.net!sun!oucsace!gwelch
From: gwelch@oucsace.cs.ohiou.edu (Grattan Welch)
Subject: WWW Browser for Windows
Message-ID: <Cx9swC.Mp3@oucsace.cs.ohiou.edu>
Organization: Ohio University CS Dept,. Athens
Date: Thu, 6 Oct 1994 21:26:35 GMT
Lines: 5


I am looking for a WWW browser (not Mosaic) that can be used with Windows
running in standard mode.  The program should be able to handle graphics
like Mosaic can.  Is such a program available?


From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: WWW setup, again [Re: mosaic]
Message-ID: <1994Oct6.160741.22681@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
References: <3711s7$qt9@mserv1.dl.ac.uk>
Distribution: bionet
Date: Thu, 6 Oct 1994 16:07:41 GMT
Lines: 217

Karl-Heinz Worm (worm@dsa.mpi-muelheim.mpg.de) wrote:

: Sorry about the following question but how/where can I watch
: bionet.software.www? Hope its not too stupid.


bionet.software.www is like any other newsgroup in the bionet system. 
As WWW is slightly advanced in terms of being a different communication 
technology, the newsgroup, additionally, keys contributions in 'html'
documents so that links are resolved in the 'hypertext' system, and may 
point to the contribution of the originators, or the subject of the message,
respectively. This server runs at the Biocomputing Facility of Basel 
University. The URL for this server is 

http://www.ch.embnet.org/bio-www/info.html

and has the following structure: 

   Contributions to the Group [this is a chronological, marked-up page] 
      Servers [for services affecting retrieval or search engines, both
               announcements and updates] 
      Archives [for archives of data and any kind of massive information] 
               Descriptions [for site descriptions who update or announce 
               a site running a server] 
      Training/Services [specific services offered via WWW]
      Discussion [any discussion on topics above, as well as implementation
               or systematic issues. ] 
   Keith Robison's WWW Server Index page [Link to the site where all
               bio-www servers are registered]. 
   User-contributed Link Page [you may add your own links in WWW here, or 
               have a message sent to the newsgroup from Mosaic (forms 
               required)]

To access the information provided by this and remote WWW sites you need a
program (called WWW client or browser) that allows to communicate with the
remote WWW server. The browser may either be locally installed or on a remote
computer. If you are directly connected to the Internet it is recommended 
to install the client software locally. The disadvantage of accessing the 
Web by a remotely running client is a lack of full functionality and poorer 
performance. 

If your computer is directly connected to the Internet and you want to 
use WWW, you should install a browser. The advantages of a locally running 
browser are full functionality and better performance. WWW browsers are 
available for most environments including: 

* AIX
* HP-UX
* IRIX
* MacOS 7.x
* MS Windows 3.x
* NeXTStep
* OSF/1
* Ultrix
* VMS
* X11/Motif
WWW browser software is copyrighted but usually free for academic use. 
Specifically, WWW browser software is available from FTP.NCSA.UIUC.EDU
in the /Mosaic directory, or VMS versions possibly on info.cern.ch.


-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=

All this, and more, will be presented in the information teaching series 
as announced by Florian Eggenberger and the information will start flowing 
at October 10, 1994. We are well aware of a 'catch22' situation which 
implies that the information on WWW is not suitable to be viewed by WWW
itself. Therefore, the Newsgroup bionet.software.www is used. The following
information is true for all bionet groups as far as the principle goes, 
and has been adapted to be valid for bionet.software.www specifically.


Subject: BIOSCI:EMAIL/USENET INSTRUCTIONS 
==========================================

The BIO-WWW/bionet.software.www newsgroup is ready for operation. 
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++


Subscribing to this group:
**************************

IF YOU USE USENET NEWS: you need do nothing other than participate in
bionet.software.www when it appears in your newsreader. Depending upon your
news software, this may entail you having to answer a prompt indicating that 
you want to subscribe. You might also try the command "g bionet.software.www" 
in rn-like newsreaders. 

IF YOU ARE LOCATED IN EUROPE, AFRICA, OR CENTRAL ASIA: 
please send the word 

help

in the body of your message to MXT@dl.ac.uk to retrieve general server usage
instructions. To subscribe to the BIO-WWW list, first be sure that you are 
sending mail from the address at which you wish to receive news postings, 
and then send the command 

SUB bionet-news.bionet.software.www

to MXT@dl.ac.uk. This message will be automatically read by the computer and
your e-mail address will be extracted from the mail header and added to the 
list. 

IF YOU ARE LOCATED IN THE AMERICAS OR THE PACIFIC RIM: 
log in to the computer account in which you would like to receive mail 
(not an account that you use infrequently) and send a mail message to the 
Internet address 

biosci-server@net.bio.net

Leave the Subject: line of the message blank and enter the following line 
into the body of the mail message: 

subscribe bio-www

This message will be automatically read by our computer and your e-mail address
will be extracted from the mail header and added to the list. 

Canceling your subscription:
****************************

IF YOU ARE LOCATED IN EUROPE, AFRICA, OR CENTRAL ASIA: first be
sure that you are sending mail from the address at which you signed up to 
receive news postings, and then send the command (in the body of your mail 
message) 

UNSUB bionet-news.bionet.software.www

to MXT@dl.ac.uk. This message will be automatically read by the computer and
your e-mail address will be extracted from the mail header and removed from the
list. 

IF YOU ARE LOCATED IN THE AMERICAS OR THE PACIFIC RIM: send a
message to biosci-server@net.bio.net exactly as described above for subscribing
except include the text 

unsubscribe bio-www

in the body of the message. Please be sure to send the message from the account
whose address matches the one on the list. If your address differs, we will 
be notified automatically and will remove you manually from the list if we 
can determine what was your old address. Please contact 
biosci-help@net.bio.net if you have problems. 

IF YOU HAVE A PROBLEM:
**********************

Please send a message to one of the following addresses depending upon your
location 

Address                              Location
-------                              --------
biosci@daresbury.ac.uk               Europe, Africa, and Central Asia
biosci-help@net.bio.net              Americas and the Pacific Rim

and someone on the staff will help you. PLEASE DO NOT send mail to our personal
e-mail addresses as this will delay a response to your request for help. 

How to post a message to the group:
***********************************

If you use news, simply post a message into bionet.software.www. Be sure to 
set your "distribution" to either bionet or world or else the message might 
not leave your site!! 

NOTE - this group is moderated and posts will not appear automatically until 
the moderator receives and approves them. 

To post by e-mail, mail your message to one of the following addresses 
depending upon your location: 

Posting Address                      Location
---------------                      --------
bio-www@daresbury.ac.uk              Europe, Africa, and Central Asia
bio-www@net.bio.net                  Americas and the Pacific Rim

PLEASE DO NOT SEND SUBSCRIPTION REQUESTS TO THE POSTING
+++++++++++++++++++++++++++++++++++++++++++++++++++++++
ADDRESSES as you will bother everyone on the newsgroup!!!
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++

How to reply to a message on the group:
***************************************

If you are using a newsreader, simply use the reply or follow-up command on 
your newsreader (these vary from program to program) to send either private 
or public replies. 

If you are using e-mail, replies to messages that you receive will *NOT* be
automatically returned to the group. This is the standard for Internet mailing
lists as opposed to BITNET LISTSERVs which often send all replies back to 
everyone. You must be certain that your reply contains either of the two 
newsgroup posting addresses above in your message header if you want to share 
it with everyone on the group. Otherwise in most cases your reply may go back 
to only the original poster of the message to which you are replying. 

ALWAYS be certain that you examine the address on your messages before you send
them!!! Once a message is sent there is no way to cancel it or bring it back!!!
Some non-Internet compliant mail systems may attempt to send replies to our
error-trapping address called BIOSCI-REQUEST. If yours does this, please be 
sure to readdress your message to bio-www@net.bio.net or 
bio-www@daresbury.ac.uk if you want to send it to the newsgroup. 






Regards
Reinhard Doelz

-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!rutgers!gatech!swrinde!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!news.mic.ucla.edu!news.bc.net!vanbc.wimsey.com!unixg.ubc.ca!quartz.ucs.ualberta.ca!news.ucalgary.ca!pc22.mid.ucalgary.ca!user
From: macklon@acs.ucalgary.ca (PMacklon)
Subject: Re: EIA (ELISA) software
Message-ID: <macklon-0610941035080001@pc22.mid.ucalgary.ca>
Date: Thu, 6 Oct 1994 18:35:08 GMT
References: <1994Oct5.134136.20645@galileo.cc.rochester.edu>
Organization: U. of C.
Lines: 35

In article <1994Oct5.134136.20645@galileo.cc.rochester.edu>,
mshelly@troi.cc.rochester.edu (Mark A. Shelly) wrote:

> Simple question:
> 
> I'm looking for options for EIA or ELISA software to assist in analysis of 
> these assays. Should include robust analysis options, along with import and
> export options. 
> 
> We're considering Macintosh, DOS, and Windows solutions. Is anything
> cross-platform compatible?
> 
> Thanks in advance,
> 
> Mark Shelly, M.D.
> University of Rochester

We use (and have not had a plague of troubles with) Delta Soft III. 
Contact the manufacturer for more information:

BioMetallics, Inc.
P.O. Box 2251, Princeton, NJ 08543
609-275-0133
800-999-1961
fax 609-275-9485

I do not if it has cross platform capabilities, but does have
export-ability.  We are running it on an old Mac SE, connected to a
Bio-Tek EL340 Elisa reader.

Good luck.

Peter
> mshelly@medicine.rochester.edu
> (716)461-6821

From owner-software@net.bio.net Wed Oct 05 23:00:00 1994
Path: biosci!daresbury!hgmp.mrc.ac.uk!nimp003.nimr.mrc.ac.uk!bionir
From: bionir@nimr.mrc.ac.uk (Frank Norman)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet: Biotechnet
Date: 6 Oct 1994 17:30:05 GMT
Organization: National Institute for Medical Research
Lines: 27
Message-ID: <bionir.630.0@nimr.mrc.ac.uk>
References: <sspencer-260994203725@f181-207.net.wisc.edu> <tan-2809941449410001@smac.ethz.ch> <1994Sep29.181744.29696@genes.icgeb.trieste.it> <1994Oct1.142817.8747@mbcf> <36rkur$nbj@nyx10.cs.du.edu>
NNTP-Posting-Host: nimp003.nimr.mrc.ac.uk
Xref: biosci bionet.molbio.methds-reagnts:19307 bionet.software:9553

In article <36rkur$nbj@nyx10.cs.du.edu> rnusbick@nyx10.cs.du.edu (robert nusbickel) writes:
>From: rnusbick@nyx10.cs.du.edu (robert nusbickel)
>Subject: Re: Promega on the Internet
>Date: 4 Oct 1994 07:22:35 -0600
>How's about a service which would be sort of like a directory 
>of all the suppliers information, including ordering information, 
>protocols, and descriptions of the materials, and make this available 
>through the net? It certainly would be advantageous to the suppliers to 
>put their information into one location and it would be great for 
>researchers to have only one place to check on reagents, etc. What do you 
>think?

I was just about to ask whether such a thing exists - I guess it doesn't!  
But there is something called Biotechnet, which has some basic info.  

telnet biotechnet.com
login BIOTECH
password bguide

-----
Frank Norman             |  National Institute for Medical Research
Deputy Librarian         |  The Ridgeway, Mill Hill, London NW7 1AA
                         |
f-norman@uk.ac.mrc.nimr  |  tel 081 959 3666 ext 2380 fax 081 913 8534

f-norman@nimr.mrc.ac.uk


From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!server2.rz.uni-leipzig.de!news.urz.tu-dresden.de!TUDURZ!petzoldt
From: petzoldt@TUDURZ.urz.tu-dresden.de (Thomas Petzoldt Hydrobiologie)
Newsgroups: bionet.software
Subject: Re: Software for organizing reprints
Date: 4 Oct 94 08:37:38 GMT
Organization: TU Dresden (URZ)
Lines: 22
Message-ID: <petzoldt.781259858@TUDURZ>
References: <9409270002.AA21919@phage.cshl.org>
NNTP-Posting-Host: tudurz.urz.tu-dresden.de

lodhi@CSHL.ORG (Muhammad A. Lodhi) writes:

>Hello Netters:
>Does anyone know about any shareware for organizing reprints?  For
>organizing my collection of the references and reprints.  Any lead will be
>appreciated.    
>Thanks in advance
>Muhammad Lodhi

BIBDB (bibdb14e.zip) from Eyal Doron, which is distributed as a literature
database manager for TeX databases may also be used for general references
management. I am very satisfied with it. 

The best: It's FREE.

  Thomas

--
------------------------------------------------------------------------------
Thomas Petzoldt, Institut for Hydrobiology, Dresden University of Technology
petzoldt@tudurz.urz.tu-dresden.de           
Phone: +49-351-463 4954 / Fax: +49-351-463 7108

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!sunic!news.funet.fi!news.csc.fi!news.helsinki.fi!kruuna!stenberg
From: stenberg@cc.Helsinki.FI (Dag Stenberg)
Newsgroups: bionet.software
Subject: Re: Which Mac for NIH Image?
Date: 7 Oct 1994 08:56:15 GMT
Organization: University of Helsinki
Lines: 24
Distribution: world
Message-ID: <3732ff$nvj@hybrid27.Helsinki.FI>
References: <106303186wnr@genesys.demon.co.uk>
NNTP-Posting-Host: kruuna.helsinki.fi
Mime-Version: 1.0
Content-Type: text/plain; charset=ISO-8859-1
Content-Transfer-Encoding: 8bit
X-Newsreader: TIN [version 1.2 PL0]

Duncan Clark (Duncan@genesys.demon.co.uk) wrote:
> What is the minimum configuration that Image requires 
> without taking O/N to do the simplest of tasks?

You can fetch the newest manual from zippy.nimh.nih.gov with anonymous
ftp. My manual is not absolutely recent, but it says that at least 4 Mb
of memory is required. A monitor capable of displaying 256 gray shades
or color is also needed. "It normally needs an FPU". 
  Our ver 1.53 is actually given 4.5 Mb, although the manual says it
will work with 2.5 Mb. Our System 7 takes up 2.5 Mb, so it would seem to
me that 4 Mb is not perhaps enough.
  I have never tried running Image on any SE30, the slowest machines we
have here.

------------------------------------------------------------------
Dag Stenberg     MD PhD                    stenberg@cc.helsinki.fi
Institute of Biomedicine		   tel: int.+358-0-1918532
Department of Physiology                   fax: int.+358-0-1918681
P.O.Box 9       (Siltavuorenpenger 20 J)   tlx: 1002125 finuh sf
FIN-00014 University of Helsinki,Finland   
        X.400:   /C=FI/A=FUMAIL/P=INET/O=HELSINKI/OU=CC/S=STENBERG/
------------------------------------------------------------------



From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Re: WWW Browser for Windows
Message-ID: <1994Oct7.083627.15741@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
References: <Cx9swC.Mp3@oucsace.cs.ohiou.edu>
Date: Fri, 7 Oct 1994 08:36:27 GMT
Lines: 17

Grattan Welch (gwelch@oucsace.cs.ohiou.edu) wrote:

: I am looking for a WWW browser (not Mosaic) that can be used with Windows
: running in standard mode.  The program should be able to handle graphics
: like Mosaic can.  Is such a program available?

Watch bionet.software.www, starting next monday, the WWW teleteaching 
project will tell you about Cello and WinWeb. 

Regards
Reinhard 

-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!uknet!daresbury!not-for-mail
From: Dietmar Tietz <Dietmar.Tietz@agrar.uni-giessen.de>
Newsgroups: bionet.software
Subject: Re: XY->digital
Date: 7 Oct 1994 09:27:23 +0100
Lines: 29
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <3730pb$p3f@mserv1.dl.ac.uk>
MIME-Version: 1.0
Original-To: bio-soft@dl.ac.uk


> Help.
> I'm looking for a program to digitize XY data from a strip chart recorder 
> following scanning it into something like a bitmap image.  I know of a 
> commercial product, UN-PLOT-IT, I believe, from a Utah company however I would 
> like to know if there is shareware or public domain software available.  
> Thanks in advance.
> 
> schlyer@um.cc.umich.edu
> 
There is a nice little program around called DataThief.  It is freeware 
and it is available from the Mac-Info archives at Stanford University and its
mirror sites.  I believe it was in the graphics directory.  If you cannot 
find it, please contact me.

Cheers,

Dietmar Tietz

******************************************************************
*           Dietmar Tietz, Ph.D.,  Research Scientist            *
*            Biostatistics, Justus-Liebig-University             *
*            Ludwigstr. 27, D-35390 Giessen, Germany             *
*                  Phone: +49-(641)-702-6015                     *
*                   Fax: +49-(641)-702-5995                      *
*              Email: Dietmar.Tietz@Uni-Giessen.de               *
******************************************************************



From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!pipex!lyra.csx.cam.ac.uk!bjd12
From: bjd12@cus.cam.ac.uk (Ben Davis)
Newsgroups: bionet.software
Subject: HB plus ?
Date: 7 Oct 1994 08:53:42 GMT
Organization: University of Cambridge, England
Lines: 19
Message-ID: <3732am$nkt@lyra.csx.cam.ac.uk>
NNTP-Posting-Host: grus.cus.cam.ac.uk
X-Newsreader: TIN [version 1.2 PL2]

Hi,

I seem to remember a program called (smthg like) HB plus, for locating 
hydrogen bonds in a protein structure. But, I've lost any details I might
once have had - anyone got an ftp site or contact address for me ?

Thanks,

Ben

--
______________________________________________________________________________

Ben Davis,
MRC Protein Function and Design,
Cambridge, UK
______________________________________________________________________________

"They can make me do it, but they can't make me do it with dignity."

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Path: biosci!agate!msuinfo!harbinger.cc.monash.edu.au!bunyip.cc.uq.oz.au!marlin.jcu.edu.au!news
From: robert@chironex.jcu.edu.au
Subject: Re: Promega on the Internet
Message-ID: <1994Oct7.052903.12602@marlin.jcu.edu.au>
Sender: news@marlin.jcu.edu.au (USENET News System)
Organization: James Cook University
X-Newsreader: <WinQVT/Net v3.9>
Date: Fri, 7 Oct 94 05:29:03 GMT
Lines: 25
Xref: biosci bionet.molbio.methds-reagnts:19340 bionet.software:9556

In article <weixCx6JqI.FKE@netcom.com> weix@netcom.com (Patrick Weix) writes:

>I tell you, I would much rather grep a database than thumb through
>catalog after catalog trying to guess where all my items are listed.
>Another plus, will make comparison shopping a snap.
Another bonus is that we can see from country to country what the prices 
are like, thereby stopping unnecessary loading of prices !


Cheers,



Robert

-------------------------------------------------------------------------
Dr Robert J. Coelen                                  fax:   61-77-791 526
Dept of Biomedical and Tropical Veterinary Sciences  phone: 61-77-815 024
James Cook University of North Queensland
Townsville-just-about-on-THE-reef, Q, 4811
-----------------------from the land d       r---------------------------
                                      o     e
                                       w   d
                                        n n
                                         u

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!agate!howland.reston.ans.net!EU.net!sunic!news.lth.se!news.lu.se!bosse-q840.wblab.lu.se!Bo.Servenius
From: Bo Servenius <Bo.Servenius@wblab.lu.se>
Subject: RAID for DNA databases???
Message-ID: <1994Oct7.160326.7465@nomina.lu.se>
X-Xxmessage-Id: <AABB3001F8013821@bosse-q840.wblab.lu.se>
X-Xxdate: Fri, 7 Oct 94 17:04:01 GMT
Sender: news@nomina.lu.se (USENET News System)
Nntp-Posting-Host: bosse-q840.wblab.lu.se
Organization: Lund university, Sweden
X-Useragent: Version 1.1.3
Date: Fri, 7 Oct 1994 16:03:26 GMT
Lines: 21

Dear Netters!

I am considering to buy a SPARCstorage Array 100 for my Sun
Sparcstation10-54
system. I am running gcg backage and the standard databases as EMBL
and Swissprot.
However I foresee that these databases and other db I would like to
install will
fill up my disks within some few month and think that a disk array
would be the final solution to the ratrace inbetween my disks and
the db.

I have no experience of the technic nor the RAID concepts. For
example how will the different RAID levels influence the performance
of db I/O for our applications.

Any comments or tips would be very much appreciated.

yours

BOSSE

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!uknet!bcc.ac.uk!arco2.afrc.ac.uk!pc0519.ri.afrc.ac.uk!user
From: lawa@bbsrc.ac.uk (Andy Law (Big Nose))
Newsgroups: bionet.software
Subject: Re: Can DNAsis replace GCG package? Or almost??
Date: 7 Oct 1994 12:16:13 GMT
Organization: Roslin Institute
Lines: 46
Message-ID: <lawa-0710941317180001@pc0519.ri.afrc.ac.uk>
References: <36vkk9$gtq@mace.cc.purdue.edu> <17047852A.A428ENDE@VM1.SARA.NL>
NNTP-Posting-Host: pc0519.ri.afrc.ac.uk

In article <17047852A.A428ENDE@VM1.SARA.NL>, A428ENDE@VM1.SARA.NL wrote:

> In article <36vkk9$gtq@mace.cc.purdue.edu>
> Although we bought DNAsis on a Mac, I still believe that we made the wrong 
> dessision. With a 586 (which is much cheaper than a PowerMac 8100) you can 
> indeed run linux and take advantage of all the software available in the Unix
> environment and you have a very fast PC with all the advantages and programs
> in this environment (there are also a lot of Public domain and Shareware
> available).

You can also access UNIX environments from a Mac. Just as easily (if not
easier). There is also a lot of Public/Shareware software available for
the Mac as well. Hell, you can even run PC software on the PowerMacs with
Softwindows, although not at any speed :)

The PowerMac 8100 is too pricy compared to the 7100. The increase in
performance that you get with the faster model is not worth the extra
money. If you decide to go down the Mac route, then I reckon the 7100 is
the best bet at the moment. Prices do tend to fluctuate rapidly though and
there are all sorts of rumours about new models kicking around.

As to MacDNAsis being buggy, well I can't comment on that because I
haven't seen it, but I get the general impression that most of the
micro-based DNA analysis software is crappy, difficult to use and full of
bugs. I also get the feeling that so many scientists are so used to having
to fight with monolithic mainframe programs that they just accept whatever
lands in front of them on their PC and assume that it is just the way
things are. THAT MAKES ME MAD!!!!

The only way that the software companies are ever going to produce decent
software that does the job and is easy to use is if we the users make
their lives miserable until they do so. If you find a program that is not
intuitive or which makes your job more difficult to do than it might be,
then tell them about it. And keep telling them about it until they change
it.

I'm sorry, I have digressed from the subject of the original posting. To
get back a bit more to the thread of things, DNASTAR is full of bugs and
dreadful to use and the ABI software is little better. So, it seems, is
MacDNAsis. Let's have a crusade against this stuff. Let the publishers
know what you think.

Andy Law

( Lawa @ bbsrc.ac.uk                     Big Nose in Edinburgh )
           --- Campaigning for usable software ---

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!Austria.EU.net!newsfeed.ACO.net!swidir.switch.ch!cisun2000.unil.ch!pcanat402.unil.ch5‚ßÌ@!gilles.bronchti
From: gilles.bronchti@ia.unil.ch (Gilles Bronchti)
Newsgroups: bionet.software
Subject: Re: Which Mac for NIH Image?
Date: Fri, 7 Oct 1994 12:11:19 UNDEFINED
Organization: Institut d'Anatomie UNILausanne
Lines: 32
Distribution: world
Message-ID: <gilles.bronchti.49.00816A49@ia.unil.ch>
References: <106303186wnr@genesys.demon.co.uk> <3732ff$nvj@hybrid27.Helsinki.FI>
NNTP-Posting-Host: pcanat402.unil.ch
X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #1]

In article <3732ff$nvj@hybrid27.Helsinki.FI> stenberg@cc.Helsinki.FI (Dag Stenberg) writes:
>From: stenberg@cc.Helsinki.FI (Dag Stenberg)
>Subject: Re: Which Mac for NIH Image?
>Date: 7 Oct 1994 08:56:15 GMT

>Duncan Clark (Duncan@genesys.demon.co.uk) wrote:
>> What is the minimum configuration that Image requires 
>> without taking O/N to do the simplest of tasks?

>You can fetch the newest manual from zippy.nimh.nih.gov with anonymous
>ftp. My manual is not absolutely recent, but it says that at least 4 Mb
>of memory is required. A monitor capable of displaying 256 gray shades
>or color is also needed. "It normally needs an FPU". 
>  Our ver 1.53 is actually given 4.5 Mb, although the manual says it
>will work with 2.5 Mb. Our System 7 takes up 2.5 Mb, so it would seem to
>me that 4 Mb is not perhaps enough.
>  I have never tried running Image on any SE30, the slowest machines we
>have here.

We are currently running NIH-Image on a quadra 950 with 32MB ram. 
You can run Image with much less memory (although I would not recommend less 
than 8 Mb, if you have enough disk space for swap. But, if you need to open a 
reasonable number of images you will rapidly run out of memory. Moreover, 
memory swaps are very slow.

Gilles
Gilles Bronchti
Institute of Anatomy
University of Lausanne
rue du Bugnon, 9
1004 Lausanne - Switzerland
gilles.bronchti@ia.unil.ch

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!uknet!daresbury!not-for-mail
From: joshi@bioinfo.ernet.in (R.R.Joshi)
Newsgroups: bionet.software
Subject: Query about promoter seq
Date: 7 Oct 1994 08:12:22 +0100
Lines: 18
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <372scm$lor@mserv1.dl.ac.uk>
Original-To: bio-soft@dl.ac.uk

Hi everybody,
	This may be a simple thing to do, but do not know how to do it.
I have a set of eight DNA sequences, out of which four are part of promoter
sequences and the other four are non-promoters. I which to find which four
are promoters and the nonpromoters.
Is there any server or software which can do this fast.? Can I use any search
program to find the promoter sequence?
Thanks in advance
R.R.Joshi
####################################################################
# Dr.R.R.Joshi                     * Tel: 330195                   #
# c/o Prof.A.S.Kolaskar            * Fax: 330087                   #
# Bioinformatics Centre            * email: joshi@bioinfo.ernet.in #
# University of Poona              *                               #
# PUNE-411007                      *                               #
# INDIA                            *                               #
####################################################################


From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!daresbury!trane.uninett.no!eunet.no!nuug!EU.net!uunet!newsflash.concordia.ca!canopus.cc.umanitoba.ca!orwell!frist
From: frist@ccu.umanitoba.ca (Brian Fristensky)
Newsgroups: bionet.software
Subject: Re: Can DNAsis replace GCG package? Or almost??
Date: 6 Oct 1994 21:17:44 GMT
Organization: The Univeristy of Manitoba.
Lines: 51
Distribution: world
Message-ID: <371pho$9nd@canopus.cc.umanitoba.ca>
References: <36vkk9$gtq@mace.cc.purdue.edu>
Reply-To: frist@ccu.umanitoba.ca
NNTP-Posting-Host: orwell.cc.umanitoba.ca

In article gtq@mace.cc.purdue.edu, xniu@mace.cc.purdue.edu (Xiaomu Niu) writes:
> 	We narrowed our choices down to two:
> 		(1) a 486/586 pc running linux and X-windows
> 		(2) a Machintosh or a Power Mac
> 
> 	With the first one, we can run MS-Windows with Hitachi's
> DNAsis for window, or we install Linux and run GDE plus other freely
> availabe sequence analysis programs for unix, something like BIRCH 
> (but running on a pc).
> 
> 	With the second choice, we probably have to purchase the    
> MacDNAsis from Hitachi. Or we can try GeneWorks (?) also.
> 
> 	But here is the question: (sorry for the long introduction)
> Can DNAsis replace GCG completely or nearly? What about speed? It
> seems we have people here running DNAsis on a Mac SE with a CD-ROM
> happily. If we understand right, GDE covers most of GCG's functions,
> and it's available for free.
> 
One of the main reasons for creating BIRCH in the first place (aside from the
fact that I had free access to Unix workstations and NO FUNDS to buy
commercial software) was that there is no such thing as a package that
does everything. GCG does some things better than most other packages, some
things less well, and many things not at all. The same will be true of 
DNAsis, GeneWorks, the Staden programs, or any single package. No one 
package does everything, and certainly none do everything well.

BIRCH is nothing more than a hierarchical directory structure of databases, 
programs, and documentation. The beauty of GDE is that it is trivial to add
new programs to the 
menus. If you tie yourself to a single commercial package, you have only
the capabilities that the authors build into it, and have to interconvert
file formats when you want to use programs from elsewhere. On a system
such as BIRCH, we can mix and match programs from many sources, letting
GDE take care of converting file formats for us. At the same time, all of
the programs from the various packages (eg. FASTA, XYLEM, FSAP, PHYLIP, MBCRR,
Oxford, etc.) are still useable as standalone programs, if desired.

===============================================================================
Brian Fristensky                | 
Department of Plant Science     |  A question is like a knife that slices
University of Manitoba          |  through the stage backdrop and gives us
Winnipeg, MB R3T 2N2  CANADA    |  a look at what lies hidden behind.
frist@cc.umanitoba.ca           |  
Office phone:   204-474-6085    |  Milan Kundera, THE UNBEARABLE LIGHTNESS 
FAX:            204-261-5732    |  OF BEING
===============================================================================





From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!zeus.rbi.informatik.uni-frankfurt.de!jurpool0.rz.uni-frankfurt.de!brion.rz.uni-frankfurt.de!jui
From: jui@brion.rz.uni-frankfurt.de (Uwe Harmening)
Newsgroups: bionet.software
Subject: Plant sociology
Date: 7 Oct 1994 16:05:35 GMT
Organization: University Frankfurt/M
Lines: 25
Message-ID: <373rkf$iga@jurpool0.rz.uni-frankfurt.de>
NNTP-Posting-Host: brion.rz.uni-frankfurt.de
X-Newsreader: Tin 1.1 PL4

Hello,

i am looking for software to prepare tables in plant sociology. There are some 
products around which are not shareware. The ones i know do not have any
database functionality. Do you know about some software that has this
functionality and is able to produce at least raw tables out of the data?
Or do you have any other experiences?

Thanx in advance. 

--

cu

Jui


harmening@cellbiology.uni-frankfurt.d400.de

AK Molekulare Zellbiologie
Uwe Harmening
Marie-Curie-Str.9
D-60438 Frankfurt
Germany


From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!uunet!newsflash.concordia.ca!canopus.cc.umanitoba.ca!asimov!frist
From: frist@ccu.umanitoba.ca (Brian Fristensky)
Newsgroups: bionet.software
Subject: Re: Can DNAsis replace GCG package? Or almo
Date: 7 Oct 1994 14:19:36 GMT
Organization: The Univeristy of Manitoba.
Lines: 39
Distribution: world
Message-ID: <373ldo$kjl@canopus.cc.umanitoba.ca>
References: <lawa-0710941317180001@pc0519.ri.afrc.ac.uk>
Reply-To: frist@ccu.umanitoba.ca
NNTP-Posting-Host: asimov.cc.umanitoba.ca

In article 0710941317180001@pc0519.ri.afrc.ac.uk, lawa@bbsrc.ac.uk (Andy Law (Big Nose)) writes:
> In article <17047852A.A428ENDE@VM1.SARA.NL>, A428ENDE@VM1.SARA.NL wrote:
> As to MacDNAsis being buggy, well I can't comment on that because I
> haven't seen it, but I get the general impression that most of the
> micro-based DNA analysis software is crappy, difficult to use and full of
> bugs. I also get the feeling that so many scientists are so used to having
> to fight with monolithic mainframe programs that they just accept whatever
> lands in front of them on their PC and assume that it is just the way
> things are. THAT MAKES ME MAD!!!!
> ( Lawa @ bbsrc.ac.uk                     Big Nose in Edinburgh )
>            --- Campaigning for usable software ---

I think the pendulum has begun to swing the other way. I now use
a Sun Unix system for virtually everything I do: word processing, mail, graphics,
news, budget juggling, and oh yes , sequence analysis -- because these tasks
are EASIER to do in the OpenWindows environment than on any personal 
computer system I've seen. With the increasingly central role of networks
in many aspects of everyday work, Unix is beginning to look more and
more attractive. 

When you look at the cost of buying, maintaining, upgrading, and (gasp)
configuring a bunch of PC's for a large lab or department, you don't
have to get to a very large number of units before it becomes cost-
effective to buy a Unix server and X-terminals. 

Sun Microsystems has a slogan "The network IS the computer". I think this
nicely sums up many of the reasons that centralized computing is an
idea whose time has come - again.

===============================================================================
Brian Fristensky                | 
Department of Plant Science     |  A question is like a knife that slices
University of Manitoba          |  through the stage backdrop and gives us
Winnipeg, MB R3T 2N2  CANADA    |  a look at what lies hidden behind.
frist@cc.umanitoba.ca           |  
Office phone:   204-474-6085    |  Milan Kundera, THE UNBEARABLE LIGHTNESS 
FAX:            204-261-5732    |  OF BEING
===============================================================================


From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!rutgers!uwm.edu!news.alpha.net!MathWorks.Com!news.duke.edu!news-feed-1.peachnet.edu!darwin.sura.net!guvax.acc.georgetown.edu!guvax.acc.georgetown.edu!nntp
Newsgroups: bionet.software,comp.sys.mac.scitech
Subject: Re: MEDLINE on-line for a fee?
Message-ID: <1994Oct7.183227.13098@guvax>
From: dan@biochem1.basic-sci.georgetown.edu
Date: 7 Oct 94 18:32:27 -0500
References: <m3047-071094125412@blv-pm0-ip14.halcyon.com>
Distribution: World,world
Organization: Georgetown University
Nntp-Posting-Host: dan.basic-sci.georgetown.edu
Lines: 15
Xref: biosci bionet.software:9572 comp.sys.mac.scitech:2460

In article <m3047-071094125412@blv-pm0-ip14.halcyon.com> m3047@halcyon.com
(Fred Morris) writes:
>I would really love to hear from a company that is providing MEDLINE access
>over the internet;  for a fee is fine.  If it's searchable with WAIS,
>great;  if it's searchable with AppleSearch, even better.
>
>--
>
>Fred Morris      VAX/VMS, Macintosh, distributed/remote computing guru
>m3047@halcyon.com
>

Why not use grateful med from medlars/nlm?



From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!news.sprintlink.net!nwnexus!news.halcyon.com!blv-pm0-ip14.halcyon.com!user
From: m3047@halcyon.com (Fred Morris)
Newsgroups: bionet.software,comp.sys.mac.scitech
Subject: MEDLINE on-line for a fee?
Followup-To: bionet.software,comp.sys.mac.scitech
Date: 7 Oct 1994 19:59:55 GMT
Organization: VAX/VMS and Macintosh guru
Lines: 8
Distribution: usa
Message-ID: <m3047-071094125412@blv-pm0-ip14.halcyon.com>
NNTP-Posting-Host: blv-pm0-ip14.halcyon.com
Xref: biosci bionet.software:9571 comp.sys.mac.scitech:2459

I would really love to hear from a company that is providing MEDLINE access
over the internet;  for a fee is fine.  If it's searchable with WAIS,
great;  if it's searchable with AppleSearch, even better.

--

Fred Morris      VAX/VMS, Macintosh, distributed/remote computing guru
m3047@halcyon.com

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!darwin.sura.net!guvax.acc.georgetown.edu!guvax.acc.georgetown.edu!nntp
Newsgroups: bionet.software
Subject: NIH R01 grant forms
Message-ID: <1994Oct7.114704.13051@guvax>
From: dan@biochem1.basic-sci.georgetown.edu
Date: 7 Oct 94 11:47:04 -0500
Reply-To: dan@biochem1.basic-sci.georgetown.edu
Distribution: World,world
Organization: Georgetown University
Keywords: NIH R01 Grant forms
Nntp-Posting-Host: dan.basic-sci.georgetown.edu
Lines: 1

 

From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!agate!howland.reston.ans.net!EU.net!uknet!festival!news
From: ajharmar@castle.ed.ac.uk (Tony Harmar)
Subject: gene construction kit
Message-ID: <CxAs6B.1zv@festival.ed.ac.uk>
X-Posted-From: InterNews 1.0.4@bmu13.bmu.mrc.ac.uk
Sender: -Not-Authenticated-[4674]
Organization: MRC Brain Metabolism Unit
Xdisclaimer: No attempt was made to authenticate the sender's name.
Date: Fri, 7 Oct 1994 10:08:33 GMT
Lines: 5

I am trying to find an e-mail address for Textco, the publishers of
gene Contruction Kit and DNA Inspector, or for Bob Gross, the author

Help much appreciated


From owner-software@net.bio.net Thu Oct 06 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!agate!howland.reston.ans.net!EU.net!sunic!news.lth.se!news.lu.se!bosse-q840.wblab.lu.se!Bo.Servenius
From: Bo Servenius <Bo.Servenius@wblab.lu.se>
Subject: RAID for DNA databases???
Message-ID: <1994Oct7.160611.7610@nomina.lu.se>
X-Xxmessage-Id: <AABB30A5AF023821@bosse-q840.wblab.lu.se>
X-Xxdate: Fri, 7 Oct 94 17:06:45 GMT
Sender: news@nomina.lu.se (USENET News System)
Nntp-Posting-Host: bosse-q840.wblab.lu.se
Organization: Lund university, Sweden
X-Useragent: Version 1.1.3
Date: Fri, 7 Oct 1994 16:06:11 GMT
Lines: 21

Dear Netters!

I am considering to buy a SPARCstorage Array 100 for my Sun
Sparcstation10-54
system. I am running gcg backage and the standard databases as EMBL
and Swissprot.
However I foresee that these databases and other db I would like to
install will
fill up my disks within some few month and think that a disk array
would be the final solution to the ratrace inbetween my disks and
the db.

I have no experience of the technic nor the RAID concepts. For
example how will the different RAID levels influence the performance
of db I/O for our applications.

Any comments or tips would be very much appreciated.

yours

BOSSE

From owner-software@net.bio.net Fri Oct 07 23:00:00 1994
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!usc!howland.reston.ans.net!pipex!uunet!powergrid.electriciti.com!usenet
From: cdhoover@powergrid.electriciti.com (Christopher Hoover)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Promega on the Internet
Date: 7 Oct 1994 23:57:17 GMT
Organization: ElectriCiti
Lines: 31
Sender: -Not-Authenticated-[5183]
Distribution: world
Message-ID: <374n8t$mc@powergrid.electriciti.com>
References: <5OCT199423082068@aardvark.ucs.uoknor.edu>  
 <371596INNhbt@sat.ipp-garching.mpg.de>
NNTP-Posting-Host: slip30.electriciti.com
X-Posted-From: InterNews 1.0.1@slip30.electriciti.com
Xdisclaimer: No attempt was made to authenticate the sender's name.
Xref: biosci bionet.molbio.methds-reagnts:19386 bionet.software:9575

To make it easier for researchers to access technical information
regarding Invitrogen products, we have recently set up Internet
Anonymous FTP and Gopher sites.

Invitrogen Gopher/FTP sites contain:

* Invitrogen vector sequences and resrtriction analyses
* Product Manuals for use with common word processing programs
* Citations for Invitrogen expression systems, vectors and isolation
kits
* Information on new products
* E-mail addresses for Invitrogen personnel

To access our Gopher site, connect to Ògopher.electriciti.comÓ and
click on the Invitrogen folder.

For anonymous FTP, connect with the following parameters:
Host:  ftp.electriciti.com
User ID:  anonymous
Password:  enter your e-mail address here
Directory:  /invitrogen

We look forward to your comments and suggestions. 
For questions, please contact:

Christopher Hoover
Technical Service
Invitrogen Corp
800-955-6288 ext. 217
619-597-6217 Fax
cdhoover@electriciti.com

From owner-software@net.bio.net Fri Oct 07 23:00:00 1994
Newsgroups: bionet.software
Path: biosci!agate!ihnp4.ucsd.edu!usc!nic-nac.CSU.net!charnel.ecst.csuchico.edu!olivea!sgigate.sgi.com!enews.sgi.com!decwrl!netcomsv!ix.netcom.com!netcom.com!weix
From: weix@netcom.com (Patrick Weix)
Subject: Re: Can DNAsis replace GCG package? Or almost??
Message-ID: <weixCxBw1E.AFy@netcom.com>
Organization: NETCOM On-line Communication Services (408 261-4700 guest)
References: <36vkk9$gtq@mace.cc.purdue.edu> <17047852A.A428ENDE@VM1.SARA.NL> <lawa-0710941317180001@pc0519.ri.afrc.ac.uk>
Date: Sat, 8 Oct 1994 00:29:38 GMT
Lines: 14

This may sound stupid, but it all depends on the type of work that you
do. If you are doing multiple sequence alignments, you probably need
some sort of mainframe.  If you just need to edit sequences for
publication, then try some of the academic freeware on
fly.bio.indiana.edu or others.

Just my 1/50 of a dollar,

Patrick
-- 
  "The large print giveth, and the small print taketh away."
 					Tom Waits
 /------------------------------------------------------------\
 | Patrick Weix                        weix@netcom.com        |
 | UT Southwestern Medical Center      weix@utsw.swmed.edu    |
 | 5323 Harry Hines Blvd               tel: (214) 648-5050    |
 | Dallas, TX 75235                    fax: (214) 648-5453    |
 \------------------------------------------------------------/

From owner-software@net.bio.net Fri Oct 07 23:00:00 1994
Path: biosci!agate!msuinfo!netnews.upenn.edu!gopher.cs.uofs.edu!jaguar.uofs.edu!cannon
From: