From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!uwm.edu!reuter.cse.ogi.edu!netnews.cc.wwu.edu!netnews.nwnet.net!news.u.washington.edu!hobbes!sanjay
From: "Sanjaya N. Joshi" <sanjay@hobbes.chmc.org>
Newsgroups: bionet.molbio.proteins,bionet.software
Subject: Re: Programs for schematic drawings of proteins?
Date: Thu, 1 Jun 1995 16:31:57 -0700
Organization: University of Washington
Lines: 82
Message-ID: <Pine.SOL.3.91.950601162835.19917B-100000@hobbes>
References: <3goein$e5i@helka.iif.hu> <3qhv1v$de1@winx03.informatik.uni-wuerzburg.de> <1995May31.212051.16977@ucl.ac.uk>
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In-Reply-To: <1995May31.212051.16977@ucl.ac.uk> 
Xref: biosci bionet.molbio.proteins:4702 bionet.software:12238

OOPS!!
I mistakenly replied to the "Re: Protein adsorption" message. Sorry!!
I will repeat the message:
I think "rasmol"
ftp forte.mathematik.uni-bremen.de /pub/unix/visualization/rasmol
OR
ftp ftp.uni-stuttgart.de /pub/scivi/chemie/rasmol
will do that (at least the ribbon or ball-stick model of the H bond).  It 
will also convert the pseudo 3D image from the "pdb" structure data file 
to a GIF image format, which can then be printed (color/grayscale)

   _________          _________   ____sanjay@hobbes.chmc.org_________
  /        /|        /        /|
 /        / |       /        / |  Sanjaya Joshi
/--------/  |      /--------/  |  Department of Radiology, CH-69
|        | <|------|        |  |  Children's Hospital & Med. Ctr.
|   A    |--/----->|   B    |  /  Seattle, Washington 98105
|        | /       |        | /   (206) 528-2744
|________|/        |________|/
And networks for all ................................................          

On Wed, 31 May 1995, Rob Miller wrote:

> Geier Gerhard (b049@mail.fh-wuerzburg.de) wrote:
> : In article <3goein$e5i@helka.iif.hu>, szia@enzim.hu says...
> : >
> : >I am looking for programs that can draw schematic drawings of protein 
> : >structures. I am interested in the following two types of drawings:
> : >
> : >        (1) schematic representation of the [main chain] hydrogen bonding 
> : >pattern (based on known 3D structure)
> : >
> : >        (2) schematic representation of the domain structure and 
> : >disulfide bonding pattern, using a chain of several circles, each circle 
> : >representing a residue, and the type of the residue written in the 
> : >circle. This chain of circles is folded in 2D to approximately represent 
> : >the domain structure and the disulfide bonding pattern.
> : >
> : >Such drawings often appear in journals but I don't know any program that 
> : >can easily draw such things. (As to the hydrogen bonding pattern, I heard 
> : >of a program called HERA but I have no idea how to get it.)
> : >
> : >Anyone can help?
> : >
> : >Andras Szilagyi (szia@enzim.hu)
> : >Institute of Enzymology, Hungarian Academy of Sciences
> : >
> 
> : If you have found a program who is able to draw that, pleas sent me seh name 
> : of the program and the name of the server
> : Thanks in forward
> : Gerhard Geier
> 
> 
> I think Gail Hutchinson's PROMOTIF is what you are interested in.  It is 
> available by anonymous ftp on 128.40.46.11, but you will need to sign 
> a confidentiality agreement.  See pages on it and our other bioinformatics
> software at http://www.biochem.ucl.ac.uk/bsm/index.html
> 
> 
> 								rob.
> 
> 
> 
> 
> --
> -------------------------------------------------------
> Rob Miller, Ph.D.  
> 
> Biomolecular Structure and Modelling Unit (BSM),
> Department of Biochemistry and Molecular Biology,
> University College / Gower Street / London WC1E 6BT.
> United Kingdom.
> 
> Tel: 44 171380 7777 x3896 
> Fax: 44 171380 7193
> 
> Internet: rmiller@bsm.bioc.ucl.ac.uk
> http://www.biochem.ucl.ac.uk/~rmiller
> -------------------------------------------------------
> 
> 

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!news.clark.net!NewsWatcher!user
From: douglas@clark.net (Douglas Hale)
Newsgroups: bionet.software
Subject: Power
Date: Thu, 01 Jun 1995 21:34:11 -0400
Organization: Clark Internet Services, Inc.
Lines: 2
Message-ID: <douglas-0106952134110001@168.143.5.183>
NNTP-Posting-Host: douglas-ppp.clark.net
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=ISO-8859-1
Content-Transfer-Encoding: 8bit

Is anyone aware of any mac software that can do power analysis/sample size
determination. Thank you.

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!CORNELL.EDU!gma2
From: gma2@CORNELL.EDU (Gregory M. Acland)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: 2 Jun 1995 05:18:48 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 20
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <v02110202abf47a39ac5e@[132.236.236.44]>
NNTP-Posting-Host: net.bio.net

Re:
1.lpss@unixg.ubc.ca (Alex Chang) wrote:
  > I am looking for a Mac PostScript converter or viewer
2. Andy.Law @ bbsrc.ac.uk wrote
  > There is a rather flaky Mac version of Ghostscript around

Ghostscript is huge (10 Mb?) slow and awful, not practically useful.

Showpages is around at most sites and is a great print only utility,
supports drag and drop.

Gregory M. Acland        	       	       	       	       	  (607) 256-5684
[phone]
Center for Canine Genetics & Reproduction       	  (607) 256-5689 [fax]
James A. Baker Institute for Animal Health      	   gma2@cornell.edu
College of Veterinary Medicine
Cornell University
Hungerford Hill Rd, Ithaca, New York 14853



From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!news.sprintlink.net!demon!uknet!gdt!bsspak
From: bsspak@bath.ac.uk (P A Keller)
Subject: Re: General Bio Software
Message-ID: <D9JtzF.CH9@bath.ac.uk>
Reply-To: P.A.Keller@bath.ac.uk
Organization: Collaborative Computational Project 4, Daresbury Laboratory, UK
References: <wmcqueen-2905950034470001@tiger.infolane.com>
Date: Fri, 2 Jun 1995 14:09:13 GMT
Lines: 28

In the referenced article, wmcqueen@infolane.com (Will McQueen) writes:
>Hello, all!
>

[snip]

>   Any ideas?  This is the only newsgroup I could find where this type of
>posting would be appropriate.  Do you know of any others?  WWW sites,
>perhaps?  FTP?  Anything.  Thanks!
>

I don't know this package in any detail, but the Pharmacy School here at Bath
has developed software for computer-aided distance learning. Try the URL
http://www.bath.ac.uk/PCCAL/ .

Have fun,
Peter.

========================================================================
Peter Keller.            \ 
Dept. of Biology and      \ "Not even the greatest nonsense is beyond
    Biochemistry,          \  the reach of human invention."
University of Bath,         \ 
Bath, BA2 7AY, UK.           \          --- Ryszard Kapuscinski
------------------------------\-----------------------------------------
Tel. (+44/0)1225 826826 x 4302 | Email: P.A.Keller@bath.ac.uk (Internet)
Fax. (+44/0)1225 826449        |   P.A.Keller%bath.ac.uk@UKACRL (BITNET)
========================================================================

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!news.starnet.net!wupost!howland.reston.ans.net!vixen.cso.uiuc.edu!uwm.edu!lll-winken.llnl.gov!osi-east2.es.net!oracle.pnl.gov!mica.inel.gov!cwis.isu.edu!news.cc.utah.edu!zifi.genetics.utah.edu!zinc
From: zinc@zifi.genetics.utah.edu (zinc)
Newsgroups: bionet.software
Subject: Re: PGP software
Date: 1 Jun 1995 15:12:05 GMT
Organization: assorted dsRNAs and lotsa zinc
Lines: 49
Message-ID: <3qklc5$ek6@news.cc.utah.edu>
References: <3qj3ev$oqg@ixnews4.ix.netcom.com>
NNTP-Posting-Host: zifi.genetics.utah.edu

-----BEGIN PGP SIGNED MESSAGE-----

In article <3qj3ev$oqg@ixnews4.ix.netcom.com>,
Craig Franklin <cfrank@ix.netcom.com> wrote:
>I am looking for a software package called PGP.  I stands for Pretty
>Good Protection.  It would be an incredible help to me if someone has
>it and could get back to me on it.  I am willing to trade other
>software.  Thanks a lot.
>cfrank@ix.netcom.com
>

pgp is available to us and canadian citizens under the laws/rules of
ITAR.  it may be found at net-dist.mit.edu (i believe that is the
correct site).

here's what you have to do:

telnet to net-dist.mit.edu

log on as getpgp and answer the questions

if you answer all of the questions correctly you will be told the
name of the hidden directory where pgp is kept.

after you get that name, ftp to net-dist.mit.edu, log on as anonymous,
cd to the appropriate dir and d/l the appropriate version of pgp.

there is a newsgroup dedicated to pgp, alt.security.pgp as well as
several www pages.

write if you need more info.

- -zinc


-----BEGIN PGP SIGNATURE-----
Version: 2.6.2

iQCVAwUBL83Zkk3Qo/lG0AH5AQH5AwP9GsarLfUwCe2vzvaAQnyHisz/iARBLc/R
HxYYukueURDn8bMTLyV5O6t+qmZ8UQSoKamIqSfo3/WsnR0IuDaJsB14rgOiwI5D
DbNJk234KBgZWBeHCciYk5kHoA5Gh1ZXSLPSYBq1bTJKcJ9haiud5ffztOxuPdnj
ArxZzsKN7jc=
=9e7a
-----END PGP SIGNATURE-----
-- 
patrick finerty         --      finerty@msscc.med.utah.edu
                                pfinerty@nyx10.cs.du.edu
U of Utah biochem grad student/slave in the Bass lab
easily found at (801) 585-3110 almost anytime.   rm 207 wintrobe.

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!rutgers!uwm.edu!cs.utexas.edu!news.sprintlink.net!demon!uknet!sunsite.doc.ic.ac.uk!daresbury!is.bbsrc.ac.uk!pc0519.ri.bbsrc.ac.uk!user
From: Andy.Law@bbsrc.ac.uk (Andy Law (Big Nose))
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: Fri, 02 Jun 1995 09:40:37 +0000
Organization: Roslin Institute
Lines: 19
Message-ID: <Andy.Law-0206950940370001@pc0519.ri.bbsrc.ac.uk>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: pc0519.ri.bbsrc.ac.uk
X-Newsreader: Value-Added NewsWatcher 2.0b24.0+

In article <3qlcd7$1us@nnrp.ucs.ubc.ca>, lpss@unixg.ubc.ca (Alex Chang) wrote:

  > Dear netter:
  > 
  > I am looking for a Mac PostScript converter or viewer, in order to read 
  > PostScript files using Mac computer. I'll appreciate if someone could 
  > provide that information, esp. a noncommercial program.
  > 
  > 

There is a rather flaky Mac version of Ghostscript around on the info-mac
archives somewhere I think. It is free, but  it's not that good. I can't
remember offhand if it is called GhostScript or GhostView. Try an archie
search for both and see what it spits out.
-- 
Andy Law

( Andy.Law @ bbsrc.ac.uk )
( Big Nose in Edinburgh )

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!news.primenet.com!ip168.phx.primenet.com!llward
From: llward@primenet.com (larry ward)
Newsgroups: bionet.software
Subject: need multivariate analysis software
Date: Thu, 1 Jun 1995 22:43:05 MST
Organization: Primenet
Lines: 4
Message-ID: <llward.19.0064B16B@primenet.com>
NNTP-Posting-Host: ip168.phx.primenet.com
X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #4]

if you know of a statistical package that does multivariate, logistic 
regression, please email with details. fyi i have data in excel & paradox for 
windows, can import/export to ascii etc. Thanks.
-Larry Ward, MD

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!sunserver.insinc.net!news.Direct.CA!scipio.cyberstore.ca!vanbc.wimsey.com!unixg.ubc.ca!news.bc.net!rover.ucs.ualberta.ca!news.sas.ab.ca!freenet.edmonton.ab.ca!hbestman
From: hbestman@freenet.edmonton.ab.ca ()
Newsgroups: bionet.software
Subject: Image analysis software for PC
Date: 2 Jun 1995 05:01:12 GMT
Organization: Edmonton Freenet, Edmonton, Alberta, Canada
Lines: 13
Message-ID: <3qm5uo$8q9@news.sas.ab.ca>
NNTP-Posting-Host: freenet.edmonton.ab.ca
X-Newsreader: TIN [version 1.2 PL2.2E]

I am in the process of acquiring frame grabbing and image analysis 
software. The two systems that I have been looking at is the MOCHA 
software and the CONCEPT V.i from Graftek. The latter can be integrated 
with LABVIEW (which we have already).
My particular application requires that the image be displayed on the 
computer screen, and then be captured, and analyzed.
Does anyone have any experience with these two systems, or any other 
ones. I sure would appreciate some help.
Please email me at: hbestman@kingsu.ab.ca 
Thanks.

--
HANK BESTMAN                         email: hbestman@freenet.edmonton.ab.ca

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!CS.Arizona.EDU!news.Arizona.EDU!helium.gas.uug.arizona.edu!bear
From: bear@helium.gas.uug.arizona.edu (Soaring  Bear)
Newsgroups: bionet.software
Subject: Re: helical wheel program
Date: 2 Jun 1995 22:42:02 GMT
Organization: University of Arizona, Unix Users Group
Lines: 18
Message-ID: <3qo43q$d3m@news.ccit.arizona.edu>
References: <nveldhoe-3005951749470001@p17-22.dialup.uvic.ca>
NNTP-Posting-Host: helium.gas.uug.arizona.edu

In article <nveldhoe-3005951749470001@p17-22.dialup.uvic.ca>,
Nik Veldhoen <nveldhoe@sol.uvic.ca> wrote:
>   In discussions of amino acid positioning and function along an alpha
>helix, a helical wheel diagram is sometimes desirable.  Unfortunately, I
>and my collegues  have not been able to find a simple Mac program that
>creates and positions an amino acid sequence along a helical wheel.  If
>anyone has or knows of Mac freeware or shareware that can create these
>schematic diagrams, please let me know at nveldhoe@sol.uvic.ca.  Thanks. 
>Nik Veldhoen

	In the same vein, how about a unix version, please?


--
 topo-O      O-topo       URL http://copsg2.pharm.arizona.edu/~bear/top/top
5'**. :      : .***.   ___         __     Cyber-Chemist: cancer drug design
  | | *.    .* | | |* (___        l .)    Molecular & Nutritional Biochemist
  | | | *. * | | | *   ___)OARING |__)EAR Herbs, Nutrition, Natural Dentistry

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!news.sprintlink.net!howland.reston.ans.net!vixen.cso.uiuc.edu!uwm.edu!newsspool.doit.wisc.edu!news.doit.wisc.edu!news
From: dalehn@facstaff.wisc.edu (Donald A. Lehn, Ph.D.)
Newsgroups: bionet.software
Subject: Re: "The Scientist" is looking for the best freeware and shareware
Date: 2 Jun 1995 20:26:05 GMT
Organization: University of Wisconsin Medical School
Lines: 19
Message-ID: <3qns4t$7io@news.doit.wisc.edu>
References: <finnD93Jnz.4Ey@netcom.com>
NNTP-Posting-Host: islet.medsch.wisc.edu
X-Newsreader: WinVN 0.99.3

In article <finnD93Jnz.4Ey@netcom.com>, finn@netcom.com says...
>
>
I would nominate MACAW (Multiple Alignment Construction and
Analysis Workbench) by Greg Schuler at NCBI/NLM/NIH

It is a great program for sequence alignments and is available in
Windows, WindowsNT and Mac versions.

Don

-- 
Donald A. Lehn, Ph.D.                   Phone:  (608) 263-7668
Medical Sciences Center / 3415          Fax:    (608) 262-9300
University of Wisconsin Medical School  Email:  dalehn@facstaff.wisc.edu
1300 University Avenue                  Home:   (608) 277-1025
Madison, WI 53706-1532
Diabetes Knowledgebase: http://www.biostat.wisc.edu/diaknow/index.htm


From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!rutgers!utcsri!info.physics.utoronto.ca!utzoo!mes
From: mes@zoo.toronto.edu (Mark Siddall)
Subject: Re: PAUP
Message-ID: <D9J5Jv.IFr@zoo.toronto.edu>
Date: Fri, 2 Jun 1995 05:21:30 GMT
References: <3qfcbr$sd6@portal.gmu.edu>
Organization: U of Toronto Zoology
Lines: 30

In article <3qfcbr$sd6@portal.gmu.edu> herwin@osf1.gmu.edu (HARRY R. ERWIN) writes:
>Any sign yet of the commercial version of PAUP? I understand Sinauer will 
>handle the marketing.
>

Yes indeed.  Swofford is presenttly in the pre-beta-test stage of version
4 of PAUP.  I am participating in this testing and can give you the 
following:

1) it is likely to be available in the late summer or early fall but there
   is no date yet.  Anything can happen.  Dave is working very very hard.
2) it will be distributed by Sinauer (if the welcome screen is any
   indication).
3) there is a Mac version, a PowerPC(PowerMac) version and a DOS version.
   (I believe the latter will be compilable on a SUN but I am not certain
    of this).
4) it includes parsimony, maximum likelihood, and Neibor Joining algorithms.
5) it is much faster than versions 3 and earlier.

Hope this helps.
I am sure there will be an appropriate announcement in this and relevant
newsgroups when it is available.

Mark

-- 
Mark E. Siddall                "I don't mind a parasite...
mes@vims.edu                    I object to a cut-rate one" 
Virginia Inst. Marine Sci.                     - Rick
Gloucester Point, VA, 23062

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!demon!uknet!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Re: PGP software
Message-ID: <1995Jun2.173225.16636@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
References: <3qj3ev$oqg@ixnews4.ix.netcom.com> <3qklc5$ek6@news.cc.utah.edu>
Date: Fri, 2 Jun 1995 17:32:25 GMT
Lines: 33

zinc (zinc@zifi.genetics.utah.edu) wrote:
: In article <3qj3ev$oqg@ixnews4.ix.netcom.com>,
: Craig Franklin <cfrank@ix.netcom.com> wrote:
: >I am looking for a software package called PGP.  I stands for Pretty
: >Good Protection.  It would be an incredible help to me if someone has
: >it and could get back to me on it.  I am willing to trade other
: >software.  Thanks a lot.
: >cfrank@ix.netcom.com
: >

PGP stands for Pretty Good Privacy. 

: pgp is available to us and canadian citizens under the laws/rules of
: ITAR.  it may be found at net-dist.mit.edu (i believe that is the
: correct site).

To my information, this is not entirely correct. 
"PGP is completely legal to use everywhere in the world, as long as you get 
it from the right place and as long as your nation does not outlaw the use 
of strong crypto. You can't export it from the United States or Canada, but 
it's available from places all over the world. "
quote from http://draco.centerline.com:8080/~franl/pgp/

Regards
Reinhard Doelz
EMBnet Switzerland


-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!swrinde!howland.reston.ans.net!sol.ctr.columbia.edu!news.mindlink.net!vanbc.wimsey.com!unixg.ubc.ca!hochac
From: hochac@bcu.ubc.ca (Wesley "Hoocher" Hochachka)
Newsgroups: bionet.software
Subject: Re: Power
Date: 2 Jun 1995 17:16:20 GMT
Organization: The University of British Columbia
Lines: 12
Message-ID: <3qnh14$9qc@nntp.ucs.ubc.ca>
References: <douglas-0106952134110001@168.143.5.183>
NNTP-Posting-Host: light.bcu.ubc.ca
X-Newsreader: TIN [version 1.2 PL2]

Douglas Hale (douglas@clark.net) wrote:
: Is anyone aware of any mac software that can do power analysis/sample size
: determination. Thank you.

   Have a look at JMP from the nice people who brought you SAS.  It's a really
nice conventional/exploratory data analysis package, with a heavy emphasis on
graphical presentation of results and analyses.  It also does power analysis
for t-tests, ANOVAs of various sorts, and (I think) contingency tables.  The
power analyses tell you statistical power for a given data set, as well as
sample sizes needed to obtain reasonable power from a given data set.  AND
the whole package is a lot less user-hostile than SAS.
                                                         Wesley Hochachka

From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!lamarck.sura.net!sprout.nalusda.gov!usenet
From: Doug Bigwood <dbigwood>
Newsgroups: bionet.software
Subject: Re: "The Scientist" is looking for the best freeware and shareware
Date: 2 Jun 1995 15:45:43 GMT
Organization: Genome Informatics Group
Lines: 20
Message-ID: <3qnbn7$haq@sprout.nalusda.gov>
References: <finnD93Jnz.4Ey@netcom.com>
NNTP-Posting-Host: locus.nalusda.gov
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.1N (X11; I; SunOS 4.1.3_U1 sun4m)
To: finn@netcom.com
X-URL: news:finnD93Jnz.4Ey@netcom.com

Dear Robert:

I would like to suggest that ACeDB is perhaps the best freeware
available for those working in genome analysis.  We use this
software extensively in making genome data available on the
Internet.  We have extensive documentation on ACeDB on our
WWW server (http://probe.nalusda.gov:8000/acedocs/index.html).

I hope this is helpful information for your article.

Doug

--------------------------------------------------------------------------
Douglas W. Bigwood, Ph.D.               
Manager, Genome Informatics Group       
USDA, NAL, ISD                          Voice: 301-504-6813
10301 Baltmore Blvd.                    Fax: 301-504-7473
Beltsville, MD 20705                    Internet: dbigwood@nalusda.gov
--------------------------------------------------------------------------


From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!news2.near.net!das-news2.harvard.edu!fas-news.harvard.edu!lipid!robison
From: robison@lipid.harvard.edu (Keith Robison)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: 2 Jun 1995 13:53:03 GMT
Organization: Harvard University, Cambridge, Massachusetts
Lines: 25
Message-ID: <3qn53v$g7e@decaxp.harvard.edu>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: lipid.harvard.edu
X-Newsreader: TIN [version 1.2 PL2]

Alex Chang (lpss@unixg.ubc.ca) wrote:
: Dear netter:

: I am looking for a Mac PostScript converter or viewer, in order to read 
: PostScript files using Mac computer. I'll appreciate if someone could 
: provide that information, esp. a noncommercial program.

Adobe Distiller & Acrobat is one solution, though its probably
not quite what you are looking for.  
Distiller converts your PostScript file into
something called Portable Document Format (PDF).  Distiller is
not free -- but the Acrobat viewer is (in fact, you can get the
viewer from ftp.adobe.com).  So, if your need is to distribute
PostScript documents to multiple Macs for viewing, this might
be a reasonable solution.  For general PostScript viewing, it probably
isn't.

Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison@mito.harvard.edu 



From owner-software@net.bio.net Thu Jun 01 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!vixen.cso.uiuc.edu!uwm.edu!lll-winken.llnl.gov!osi-east2.es.net!oracle.pnl.gov!mica.inel.gov!cwis.isu.edu!news.cc.utah.edu!zifi.genetics.utah.edu!zinc
From: zinc@zifi.genetics.utah.edu (zinc)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: 2 Jun 1995 03:03:34 GMT
Organization: assorted dsRNAs and lotsa zinc
Lines: 36
Message-ID: <3qlv26$1vi@news.cc.utah.edu>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: zifi.genetics.utah.edu

-----BEGIN PGP SIGNED MESSAGE-----

In article <3qlcd7$1us@nnrp.ucs.ubc.ca>, Alex Chang <lpss@unixg.ubc.ca> wrote:
>Dear netter:
>
>I am looking for a Mac PostScript converter or viewer, in order to read 
>PostScript files using Mac computer. I'll appreciate if someone could 
>provide that information, esp. a noncommercial program.

Alex Chang,

ghostscript is available for the mac and allows viewing of all sorts
of postscript files.  sorry, i don't know the location but i'm sure an
archie or gopher search will turn it up.  if not, write me and i'll
send it your way or make it avail via ftp.

ciao,

- -pjf



-----BEGIN PGP SIGNATURE-----
Version: 2.6.2

iQCVAwUBL86AaE3Qo/lG0AH5AQEimAP/cfm9t17RhBvjU40kpVYI0haukpeT1vRo
lmgMub6ev81RHV6ok1YzZoBJVCbqNBand4miC3Eq2CReZuIub+SpbPmsuHTZparH
S8yici8zqZHesJA6jf1EwjC9jnt+hG/nTsKSsPwVooPlioJyPuUTywKSFxLq7UOb
6DBVCDJawPE=
=eEyU
-----END PGP SIGNATURE-----
-- 
patrick finerty         --      finerty@msscc.med.utah.edu
                                pfinerty@nyx10.cs.du.edu
U of Utah biochem grad student/slave in the Bass lab
easily found at (801) 585-3110 almost anytime.   rm 207 wintrobe.

From owner-software@net.bio.net Fri Jun 02 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!swrinde!cs.utexas.edu!geraldo.cc.utexas.edu!netnews.uthscsa.edu!usenet
From: griess@uthscsa.edu (Gary Griess)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: 3 Jun 1995 20:34:23 GMT
Organization: U.T.Health Science Center
Lines: 7
Sender: Griess@thorin.uthscsa.edu
Message-ID: <3qqh0f$bev@cosmos.uthscsa.edu>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: phage.uthscsa.edu
X-Posted-From: InterNews 1.0.5@phage.uthscsa.edu
X-Authenticated: Griess on POP host thorin.uthscsa.edu

MacLPR is a nifty drag-and-drop application for Macs that converts and
sends Postscript files to your printer.

Gary A. Griess
Biochemistry Dept.
U.T. Health Science Center
San Antonio, TX 78284

From owner-software@net.bio.net Sat Jun 03 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!uwm.edu!vixen.cso.uiuc.edu!usenet.ucs.indiana.edu!sun2!sun1.iusb.edu!kchaudhr
From: kchaudhr@sun1.iusb.edu ("Akoona Matata")
Subject: Re: Help with Runtime [toolbook]
Message-ID: <D9Mquq.198@sun2.iusb.indiana.edu>
Sender: usenet@sun2.iusb.indiana.edu (USENET poster)
Nntp-Posting-Host: sun1.iusb.indiana.edu
Organization: Indiana University South Bend
Date: Sun, 4 Jun 1995 03:54:26 GMT
Lines: 16

Hi, I am trying to run the runtime.exe which will play or read tbk files but, 
when ever I install runtime and try to run it through file mangaer I get the 
following messge

"Cannot run without a book.  A book must be specified"

Could any one please help me out and tell me what I need to do to get this 
thing going.

You can leave me mail at kchaudhr@sun1.iusb.indiana.edu

Any responce will be greatly appreciated

Regards



From owner-software@net.bio.net Sat Jun 03 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!EU.net!Austria.EU.net!newsfeed.ACO.net!swidir.switch.ch!univ-lyon1.fr!jussieu.fr!oleane!pipex!sunic!sunic.sunet.se!news.funet.fi!ousrvr.oulu.fi!ppc.oulu.fi!user
From: mhaveri@cc.oulu.fi (Matti Haveri)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: Sun, 04 Jun 1995 20:40:17 +0200
Organization: University of Oulu
Lines: 13
Message-ID: <mhaveri-0406952040170001@ppc.oulu.fi>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: ppc.oulu.fi
Mime-Version: 1.0
Content-Type: text/plain; charset=iso-8859-1
Content-Transfer-Encoding: 8bit

:I am looking for a Mac PostScript converter or viewer, in order to read 
:PostScript files using Mac computer. I'll appreciate if someone could 
:provide that information, esp. a noncommercial program.

For viewing this is the best at the moment. It doesn't support printing yet.

<ftp://ftp.cs.wisc.edu//pub/ghost/aladdin/mac/>

For printing:

<ftp://ftp.funet.fi//pub/mac/info-mac/prn/drop-ps-113.hqx>

-Matti Haveri <mhaveri@cc.oulu.fi>

From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Newsgroups: bionet.software,bionet.general
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!newsserver.jvnc.net!newsserver2.jvnc.net!netnews.upenn.edu!msunews!harbinger.cc.monash.edu.au!news.cs.su.oz.au!inferno.mpx.com.au!metro!news
From: sfletche@extro.ucc.su.OZ.AU
Subject: Re: Refman vs Endnote 
Content-Type: TEXT/PLAIN; charset=US-ASCII
Message-ID: <NEWTNews.31927.801819756.Extro@fletche.ucc.su.OZ.AU>
Lines: 63
Sender: news@ucc.su.OZ.AU
Nntp-Posting-Host: ts-h08-15-47.ucc.su.oz.au
Organization: Information Services, Sydney University, Sydney, NSW, Australia
X-Newsreader: NEWTNews & Chameleon -- TCP/IP for MS Windows from NetManage
References: <3q3ulq$gq3@lyra.csx.cam.ac.uk>
     
Mime-Version: 1.0
Date: Tue, 30 May 1995 07:36:08 GMT
Xref: biosci bionet.software:12258 bionet.general:15583



> 
> >For you diehard Windows users, I got the latest newsletter and they saw that 
> >the Windows version is in the last phase of testing.  They don't give a 
> >release date, but say that upgrades will be $49 + shipping for users of the 
> >DOS version and suggested list price of the new version $299. 
> 
> Alternatively Refs and WinRefer together will give you almost the same
> functionality and cost you only $47.99 or 29.99 UKP.  These packages
> are both available for ftp from:
> 
> ftp://cyclin.zoo.cam.ac.uk/pub/refs/refs772.zip
> ftp://cyclin.zoo.cam.ac.uk/pub/refs/extra/wr30.zip
> 
> There is a WWW page with screen shots of Refs so you don't even have
> to try it out to see what the interface is like:
> 
> http://cyclin.zoo.cam.ac.uk/refs/refs.html
> 
> Refs is available in four languages:  English, German, Spanish and
> Japanese.
> 
> Regards,
> 
> Tim.
> 
Yes I am a die hard windows user. I almost decided to bugger the stuffing 
around, and just get endnote today, as people have given the best response 
regarding this product, but I found out it wasn't windows. I stood at the 
counter, money in hand, saying "NOT WINDOWS?????...NO WINDOWS VERSION??????" and 
the guy said, "You like Windoze?"... "YEAH!!!".... "Yeah, I guess it's more user 
friendly than dos".... then I was about to start up a discussion on the 
advantages of multitasking but thought, bugger it. Basically Refs seems great.


From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!bcm!news.msfc.nasa.gov!elroy.jpl.nasa.gov!swrinde!gatech!sdd.hp.com!spool.mu.edu!uwm.edu!msunews!harbinger.cc.monash.edu.au!news.cs.su.oz.au!metro!chuynh
From: chuynh@morgan.angis.su.oz.au (Camson Huynh)
Subject: ANNOUNCEMENT: ShadyBox version 2.0.1
Message-ID: <D9oHzC.1IH@ucc.su.OZ.AU>
Sender: news@ucc.su.OZ.AU
Nntp-Posting-Host: morgan.angis.su.oz.au
Organization: ANGIS
X-Newsreader: xrn 7.00 (Motif)
Date: Mon, 5 Jun 1995 02:37:57 GMT
Lines: 98

ShadyBox Version 2.0.1
----------------------

ShadyBox is a drawing program which enables you to box and shade regular
and irregular shaped segments of aligned multiple sequences.  It was
designed with the intention of producing PostScript output suitable for use
in publications.

Version 2.0.1 was implemented with colour features. It is now possible to
colour regions of sequences, individual residues or residues of specified
frequency. Regions may be shaded with colour or the residues themselves may
be coloured.

GreyScale is available for those wishing to use it.

ShadyBox accepts either an MSF (Multiple Sequence File), a Pretty or a
Macaw formats.

MSF files are produced by the GCG program Pileup or by ClustalW.  Pretty
files are produced by the GCG program Pretty and may include a consensus
sequence. Macaw files are produced by the Macintosh multiple sequence
alignment program, Macaw.

ShadyBox allows you to generate a PostScript file in which you can display
and print the box and shade regions.

NEW FEATURES AND FIXES
----------------------
 * scrolling fixed, also scrollbars now is static.
 * resize events, expose events of drawing area fixed.
 * redisplay of sequences after expose or resize events fixed.
 * undo a clear function fixed.
 * bug in boxall fixed.
 * bug in load saved file fixed.
 * bug in load previously saved boxall figures fixed.
 * some of the memory problems fixed.
 * lots of minor bug fixes.

New Features in version 2.0.1:

 * ShadyBox now supports colour shades, colour residues, etc....
 * New functions added. For a list of new functions, see shadyboxes.txt help. 
 * Uses a DYNAMIC COLOUR SCALE supplied by libXG.a enhancement version.
 * Uses SHADYBOX_HLPDIR environment variable to track shadyboxes.txt help.
 * Uses SHADYBOX_ALSDIR environment variable to track alscript programs.
 * Uses SHADYBOX_PS     environment variable for external postscript viewer.
                        It's default is ghostview.

COPYRIGHT
---------
ShadyBox Version 2.0.1
    (c) Copyright 1995 Camson Huynh,
    ANGIS (Australian National Genomic Information Service )

Permission to use, copy, modify, and distribute this software and its
documentation for any purpose and without fee is hereby granted,
provided that the above copyright notice appear in all copies and that
both that copyright notice and this permission notice appear in
supporting documentation.  This software is provided "AS IS" without
express or implied warranty.

REQUIREMENTS
------------

	Motif 1.X.
	X11 R4 or later.
	libXG enhanced version. ( Tarred together within this version )
		Information on libXG can be found in the libxg directory when untarred
		ShadyBox.
	Alscript. ( Tarred together within this version )
		Information on alscript can be found in the alscript145 directory when
		untarred ShadyBox.

ShadyBox has been tested and run successfully on SunOS 4.1.3 and Sun
Solaris 2.X.  It may run on other platforms aswell.


WHERE TO GET IT
---------------
ftp://morgan.angis.su.oz.au/pub/unix

Solaris platform :
    ShadyBox-2.0.1.README
    ShadyBox-2.0.1.sol.tar.gz or ShadyBox-2.0.1.sol.tar.Z

Other platforms :
    ShadyBox-2.0.1.README
    ShadyBox-2.0.1.tar.gz or ShadyBox-2.0.1.tar.Z

-----------------------------------------------------------------------------

ANGIS (The Australian National Genomic Information Service)
University of Sydney,
Australia.

General Enquiries email : help@angis.su.oz.au
WWW URL : http://morgan.angis.su.oz.au


From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!howland.reston.ans.net!news.sprintlink.net!noc.netcom.net!netcom.com!csus.edu!csulb.edu!paris.ics.uci.edu!news.service.uci.edu!buggus.mmg.uci.edu!user
From: mangalam@uci.edu (Harry Mangalam)
Newsgroups: bionet.software
Subject: Re: Simple text editor for mac wanted.
Date: Mon, 05 Jun 1995 11:44:41 -0700
Organization: Microbiology and  Molecular Genetics, UC Irvine
Lines: 31
Distribution: bionet
Message-ID: <mangalam-0506951144410001@buggus.mmg.uci.edu>
References: <3qhbf3$3bt@mserv1.dl.ac.uk> <weixD9GApA.5LC@netcom.com>
NNTP-Posting-Host: buggus.mmg.uci.edu

In article <weixD9GApA.5LC@netcom.com>, weix@netcom.com (Patrick Weix) wrote:

> (Dave Johnston) <daj@mailserver.nhm.ac.uk> writes:
> 
> >Hi,
> >I am looking for a basic (freeware) text editor for the Mac with cut, copy, 
> >paste, find, exchange etc type functions but it must be (a) 100% 
> >reliable) and (b) capable of handling very big data files (too large for 
> >simpletext/teachtext). We have Word6 but would prefer something less 
> >lumbering. Any suggestions.

Another Vote for Alpha!!

Alpha - Pete Keleher. Now *$30* shareware (and cheap at twice the price).
Also comes with Power Mac native form.  A text editor based on Ousterhout's
tcl scripting language that comes with custom setups for just about any
kind of file (HTML, TeX, Perl, C/C++, Fortran, Pascal, tcl, you name it,
and is further almost infinitely customizable via tcl.  Huge number of
predefined keybindings, can define your own.  Also has keyboard
macros, many unixy tools (grep, diff, sort), can be used as the external
editor for MacPerl, Think C, Metrowerks, etc. Carried in many Mac
Archives, but home is:
http://www.cs.umd.edu/~keleher/alpha.html

Harry
-- 
Harry J Mangalam, Microbiology and Molecular Genetics, UC Irvine,
      Irvine, CA, 92717, (714) 824-4824, fax (714) 824 8598
                 --- knowledge is fractal ---
            http://hornet.mmg.uci.edu/~hjm/hjm.html
  Computational Biology..SGI..Woodworking..Bicycling..Linux..WWW 

From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!agate!newsxfer.itd.umich.edu!gatech!newsfeed.pitt.edu!godot.cc.duq.edu!usenet
From: "Frank R. Gorga" <gorga@next.duq.edu>
Newsgroups: bionet.software
Subject: Re: Help with Runtime [toolbook]
Date: 5 Jun 1995 14:25:43 GMT
Organization: Duquesne University
Lines: 20
Message-ID: <3qv457$8jj@godot.cc.duq.edu>
References: <D9Mquq.198@sun2.iusb.indiana.edu>
NNTP-Posting-Host: phosphorus.chemistry.duq.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.1N (Windows; I; 16bit)
To: kchaudhr@sun1.iusb.edu

You probably need to make an icon for your application. The command line 
for the icon should read something like:

<path>\runtime.exe <path>\book.tbk.

In other words you need to force the toolbook run time to load a file as 
it loads itself.

--- F.R. Gorga
 

***********************************
Frank R. Gorga, Ph.D.
Dept. of Chemistry & Biochemistry
Duquesne University
Pittsburgh, PA 15282
412-396-5858 / 412-396-5683 (fax)
gorga@next.duq.edu



From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!agate!howland.reston.ans.net!gatech!newsfeed.pitt.edu!godot.cc.duq.edu!usenet
From: "Frank R. Gorga" <gorga@next.duq.edu>
Newsgroups: bionet.software
Subject: Re: Help with Runtime [toolbook]
Date: 5 Jun 1995 14:27:12 GMT
Organization: Duquesne University
Lines: 20
Message-ID: <3qv480$8jj@godot.cc.duq.edu>
References: <D9Mquq.198@sun2.iusb.indiana.edu>
NNTP-Posting-Host: phosphorus.chemistry.duq.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.1N (Windows; I; 16bit)
To: kchaudhr@sun1.iusb.edu

You probably need to make an icon for your application. The command line 
for the icon should read something like:

<path>\runtime.exe <path>\book.tbk.

In other words you need to force the toolbook run time to load a file as 
it loads itself.

--- F.R. Gorga
 

***********************************
Frank R. Gorga, Ph.D.
Dept. of Chemistry & Biochemistry
Duquesne University
Pittsburgh, PA 15282
412-396-5858 / 412-396-5683 (fax)
gorga@next.duq.edu



From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!daresbury!not-for-mail
From: (Russell Stothard) <jrs@mailserver.nhm.ac.uk>
Newsgroups: bionet.software
Subject: RESTSITE or REAP
Date: 5 Jun 1995 13:01:28 +0100
Lines: 13
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <3qurmo$7jj@mserv1.dl.ac.uk>
X-POPmail-Charset: English
Original-To: bio-software@dl.ac.uk

Hi

Does anyone have a copy of either j.c.miller's RESTSITE or d.McElroy's 
REAP. The programs are freeware and I have been unable to find a copy on 
the net.

Thanks

Russ Stothard
Russ Stothard@nhm.ac.uk
Dept Zoology
Natural History Museum
London

From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!agate!dog.ee.lbl.gov!ihnp4.ucsd.edu!network.ucsd.edu!risaacso.extern.ucsd.edu!risaacson
From: risaacson@ucsd.edu (Roger Isaacson)
Newsgroups: bionet.software
Subject: PDB importing to AutoCad 12
Date: Sun, 4 Jun 1995 07:35:39
Organization: UCSD Physics
Lines: 11
Message-ID: <risaacson.12.00079859@ucsd.edu>
NNTP-Posting-Host: risaacso.extern.ucsd.edu
Summary: AutoCad Lisp routine for importing AutoCad files
Keywords: xyz X-ray coordinates
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

I have just had the first version of a LISP  routine programmed so we can 
import Protein Data Bank files into AutoCad for 3D editing and doing fancier 
publication drawing than is usually possible with most low end 3D molecular 
graphics programs such as RasMol.  We would be interested in your comments and 
are willing to share the routine with anyone interested.

Roger Isaacson 
Physics Dept
University of Calif. San Diego
risaacson@ucsd.edu
FAX 619 534-0173

From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!usc!nic-nac.CSU.net!deernisse.fullerton.edu!user
From: DEernisse@fullerton.edu (Doug Eernisse)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: Mon, 05 Jun 1995 15:27:50 -0700
Organization: CSUF
Lines: 27
Message-ID: <DEernisse-0506951527500001@deernisse.fullerton.edu>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca> <mhaveri-0406952040170001@ppc.oulu.fi>
NNTP-Posting-Host: deernisse.fullerton.edu

In article <mhaveri-0406952040170001@ppc.oulu.fi>, mhaveri@cc.oulu.fi
(Matti Haveri) wrote:

> :I am looking for a Mac PostScript converter or viewer, in order to read 
> :PostScript files using Mac computer. 

[ ... ]

> For printing:
> <ftp://ftp.funet.fi//pub/mac/info-mac/prn/drop-ps-113.hqx>
> 
> -Matti Haveri <mhaveri@cc.oulu.fi>

I second the suggestion for drop-ps for printing. Another available
program that is useful in conjunction with its use is Lizzie Borden
for those situations when you have a huge ps file that doesn't seem
to print from drop-ps, no matter how much RAM you throw at it.
Lizzie Borden converts it to a format that then prints with drop-ps
just fine. This really saved me on April 15 when I was trying to
complete my taxes with on-line ps forms. Available at the usual 
sites.

-- 
Doug Eernisse <DEernisse@fullerton.edu>
Dept. Biological Science MH282
California State University
Fullerton, CA 92634

From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!noc.netcom.net!ix.netcom.com!netnews
From: hlthways@ix.netcom.com (Jerome Smith)
Newsgroups: bionet.software
Subject: re: refman/endnotes/PROCITE
Date: 5 Jun 1995 22:43:24 GMT
Organization: Netcom
Lines: 19
Distribution: world
Message-ID: <3r01ac$re4@ixnews3.ix.netcom.com>
NNTP-Posting-Host: ix-rnwk1-24.ix.netcom.com

Personal Bibliographics software, Inc. distributes PROCITE and
BIBLIOLINK. phone 313-996-1580, fax 313-996-4672. 

I don't have either one yet but two of my key pharmaceutical clients
do.  They seem to love it. 

Procite is a windows based - full featured bibliographic reference
management database.  Imports comma delimited or tab delim. records.
Exports to ascii or a word processor. 

I think you need to get Biblio link as well however.  It seems to be
the best (only) way to transfer downloaded records (from CD or online
database services).   

Total costs runs under $600...and they have a 30 day money back
guarantee.  I think the rep told me they just came out with a new
version too. 



From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!CLONTECH.COM!DAVIDK
From: DAVIDK@CLONTECH.COM
Newsgroups: bionet.software
Subject: Data Acquisition software
Date: 5 Jun 1995 13:59:56 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 6
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <sfd30de3.001@internet.clontech.com>
NNTP-Posting-Host: net.bio.net

Netters:
I do not use the network regularly and would like to know if there are any freeware/shareware programs for data acquisition, i.e. multichannel temperature recording to Mac or PC.
Thanks,
David Kellogg
davidk@clontech


From owner-software@net.bio.net Sun Jun 04 23:00:00 1995
Path: biosci!bcm!news.msfc.nasa.gov!elroy.jpl.nasa.gov!swrinde!gatech!newsfeed.pitt.edu!godot.cc.duq.edu!usenet
From: "Frank R. Gorga" <gorga@next.duq.edu>
Newsgroups: bionet.software
Subject: Re: Help with Runtime [toolbook]
Date: 5 Jun 1995 14:24:49 GMT
Organization: Duquesne University
Lines: 20
Message-ID: <3qv43h$8jj@godot.cc.duq.edu>
References: <D9Mquq.198@sun2.iusb.indiana.edu>
NNTP-Posting-Host: phosphorus.chemistry.duq.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.1N (Windows; I; 16bit)
To: kchaudhr@sun1.iusb.edu

You probably need to make an icon for your application. The command line 
for the icon should read something like:

<path>\runtime.exe <path>\book.tbk.

In other words you need to force the toolbook run time to load a file as 
it loads itself.

--- F.R. Gorga
 

***********************************
Frank R. Gorga, Ph.D.
Dept. of Chemistry & Biochemistry
Duquesne University
Pittsburgh, PA 15282
412-396-5858 / 412-396-5683 (fax)
gorga@next.duq.edu



From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!sol.ctr.columbia.edu!news.mindlink.net!vanbc.wimsey.com!unixg.ubc.ca!lpss
From: lpss@unixg.ubc.ca (Alex Chang)
Newsgroups: bionet.software
Subject: Mac Postscript converter/viewer
Date: 6 Jun 1995 00:54:36 GMT
Organization: University of British Columbia, Vancouver, B.C., Canada
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Thanks for those who responded to my question.

I tried various programs recommeded by those netters and found out the 
Gostscript program is the one I really need.

--
Alex Chang
Pathology
University of British Columbia
achang@hivnet.ubc.ca

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!agate!newsxfer.itd.umich.edu!gatech!news.sprintlink.net!pipex!oleane!jussieu.fr!univ-lyon1.fr!serra.unipi.it!king.ifc.pi.cnr.it!user
From: king@po.ifc.pi.cnr.it (Giuliano Kraft)
Newsgroups: bionet.software
Subject: Genetic linkage software for Mac
Date: Tue, 06 Jun 1995 17:04:03 +0100
Organization: CNR Inst. of Clinical Physiology Pisa
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Message-ID: <king-0606951704030001@king.ifc.pi.cnr.it>
NNTP-Posting-Host: king.ifc.pi.cnr.it

I am looking for a free Macintosh software package for genetic linkage
analysis.    It would be an incredible help to me if someone knows an ftp
site to find it.  Thanks a lot.

Giuliano Kraft
CNR Inst. of Clinical Physiology
Via Savi, 8
I-56100 Pisa

e-mail: king@po.ifc.pi.cnr.it

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!vector.nsk.su!eroshkin
From: eroshkin@vector.nsk.su (Alexy Eroshkin)
Newsgroups: bionet.software
Subject: (none)
Date: 6 Jun 1995 03:15:01 -0700
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To: BIO-SOFT@net.bio.net
From: eroshkin@vector.nsk.su <Alexey Eroshkin>
Subject: Protein Structure-Activity Analyzing Software Available


PROANAL version 2.0
-------------------

New software package PROANAL version 2 is freely available thru:
IuBio archive, EBI ftp and email server, NIG (Japan) ftp server.

How to get it:

1. From IuBio archive as
ftp://iubio.bio.indiana.edu/molbio/ibmpc/proanal2.exe (and proanal2.readme)

IUBio archive files are now all available by e-mail to users.
This is thru a network Gopher to Email gateway.  To start, send mail to

    gophermail@iubio.bio.indiana.edu

2. From EBI ftp and email server:

ftp.ebi.ac.uk /pub/software/dos/proanal$.exe

This is the self-extracting archive, so it should before
transferring, ftp should be set to binary transfer.

Or by sending an email message containing:
GET DOS_SOFTWARE:PROANAL.UAA
to netserv@ebi.ac.uk

Which will return the 6 files. Running UUDECODE you'll get
self-extracting
archive with the program.

3. From NIG (Japan) ftp server ftp.nig.ac.jp

 directory: /pub/dos/proanal
 file:      proanal$.exe
 URL:       gopher://gopher.nig.ac.jp:70/59/pub/dos/proanal/proanal$
            ftp://ftp.nig.ac.jp/pub/dos/proanal/proanal$.exe

-----------------------------------------------------------------
PROANAL ver 2.0 description:

Enhanced version of the program PROANAL (CABIOS, 9, 491-497, 1993)

Purpose:

* investigation of relationships between structure and activity in a family of
  evolutionary related (or/and artificially mutated) proteins/peptides
  (searching relations between data on activity and various physico-
  chemical characteristics of different regions in primary structures);
* analysis of multiple protein alignments;
* studying protein structure-function relationships;
* comparative analysis of sequences;
* protein-engineering experiment planning.

PROANAL may be used to predict protein secondary structures,
functionally or structurally important regions, antigenic determinants
(B- and T-call epitopes), transmembrane regions.

Input data:

* aligned protein amino acid sequences with data of their activity
  (pK, Km, ED50 or any other, if available).

New options:

* converts alignments from CLUSTAL output files to PROANAL input files;
* plots individual and average profiles (10 different profiles, including
  alpha-helical and beta-strand moments) for entire protein family;
* searching physico-chemically variable and conservative regions (e.g.,
  regions with low dispersion of alpha-helical moments of hydrophobicity);
* searching sites with high and low physico-chemical properties;
* database of about 100 amino acid physico-chemical properties;
* examples, extensive manual and help system.

Requirements: DOS 3.30 or later, EGA/VGA video card, 500 KB RAM.

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Alexey Eroshkin                   Research Institute of Molecular Biology
E.mail: eroshkin@vector.nsk.su    State Research Center of Virology and
Tel: +7 (3832) - 647774           Biotechnology "Vector"
Fax: +7 (3832) - 328831           Koltsovo, Novosibirsk Region
                                  633159  Russia
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++


From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!news.sprintlink.net!demon!uknet!bhamcs!news.ox.ac.uk!oxpath!enriquez
From: enriquez@molbiol.ox.ac.uk (PITA ENRIQUEZ HARRIS)
Newsgroups: bionet.software
Subject: GCK for PCs???
Date: 6 Jun 95 11:49:11 GMT
Organization: Oxford University Molecular Biology Data Centre
Lines: 7
Message-ID: <1995Jun6.114911@ania.path.ox.ac.uk>
NNTP-Posting-Host: ania.path.ox.ac.uk

Dioes anyone know if there are any plans to do a version of Gene Construction 
Kit for PCs?  Its a terrific Mac program, but I have a PC at home.

Thanks ,

Pita


From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!news.primenet.com!ssmith
From: ssmith@primenet.com (Program World Services)
Newsgroups: bionet.software
Subject: q
Date: 6 Jun 1995 06:39:53 GMT
Organization: Primenet Services for the Internet (602)395-1010
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--
-------------------------------------------------------------------------------
For Private Full Year Automotive Information for $39.95 Contact myself below. 
For anymore or future technical support contact ssmith@primenet.com directly.

Scott Smith     Program World Services    __  __     ____  ___       ___ ____
ssmith@primenet.com BBS:(209) 255-9110   /__)/__) / / / / /_  /\  / /_    /
Compuserve 74441,2713, Aol[SCOTT93727]  /   / \  / / / / /__ /  \/ /___  /

   Professional Automotive Repair Information,   Professional Job Placement
      Professional Internet Advertising,   Shareware Program Development
   
  Complete Professional Chiltons Manual Specifications from 1955-1995 for
           Domestic and Import Cars of almost all makes and models.

-------------------------------------------------------------------------------

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!news.primenet.com!ssmith
From: ssmith@primenet.com (Program World Services)
Newsgroups: bionet.software
Subject: Very Professional shop software
Date: 6 Jun 1995 06:39:18 GMT
Organization: Primenet Services for the Internet (602)395-1010
Lines: 64
Message-ID: <3r0t6m$30a@news4.primenet.com>
NNTP-Posting-Host: usr4.primenet.com
X-Newsreader: TIN [version 1.2 PL2]

***********************************************************

 S  H  O  P  M  A  N       V  E  R  S  I  O  N    2 . 0 0

-----------------------------------------------------------

  Shopman is the latest Windows release for complete
Very Professional automotive Shop Management Software,
(May also be used for services other then automotive),
Some of its options are as follows:

  1) Databases: Vendor, Stock, Non-stock, Repair Order
  (RO), Calender and Alarm, Vehicle, Customer, Payroll
  Accounts Payable, Accounts Receivable, Type Work,
  plus More.

  2) Edit: Orders, Accounts, Quotes, Invoices, Repair
  Orders, Stock Needs, Payroll, Calender, Plus more.

  3) Search: By History, Name, Model, Part, Item #,
  Vin #, License, Payroll, Employer Name, Date, Plus More.

  4) Accounts: Accounts Payable, Accounts Receive,
  Checkbook, Payroll, Tech Paid, Inventory Cost, Etc.

  5) Built-in Utilities: Searchable Help, Back-up
  Database, Customization, Terminal, Editor, Clock,
  Programable Calender, Calculator, Plus More.

  6) ALLDATA Terminal for rapid download into database
  of complex repair information and service bulletin
  updates, To make your repairs much easier.

  7) Better then a lot of commercial programs at
  hundreds below there cost.

  8) Shopman works within Windows for DLL Access
  and requires about 2 Meg to install.

  9) Shopman can be download for evaluation from
  my BBS at 209-255-9110 for a timed evaluation copy,
  the cost for shopman is $249.00, and its about
  $350.00 below its comercial competitor   and its
  better software !!!!

***********************************************************


--
-------------------------------------------------------------------------------
For Private Full Year Automotive Information for $39.95 Contact myself below. 
For anymore or future technical support contact ssmith@primenet.com directly.

Scott Smith     Program World Services    __  __     ____  ___       ___ ____
ssmith@primenet.com BBS:(209) 255-9110   /__)/__) / / / / /_  /\  / /_    /
Compuserve 74441,2713, Aol[SCOTT93727]  /   / \  / / / / /__ /  \/ /___  /

   Professional Automotive Repair Information,   Professional Job Placement
      Professional Internet Advertising,   Shareware Program Development
   
  Complete Professional Chiltons Manual Specifications from 1955-1995 for
           Domestic and Import Cars of almost all makes and models.

-------------------------------------------------------------------------------

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!biosci!not-for-mail
From: richardg@Ne.Chem.LSA.UMich.Edu (Richard Goldstein)
Newsgroups: bionet.general,bionet.biology.computational,bionet.biophysics,bionet.info-theory,bionet.molbio.evolution,bionet.molec-model,bionet.software,sci.bio.evolution,bionet.molbio.bio-matrix
Subject: Call For Papers:  Evolution and Structure of Biomolecules
Date: 5 Jun 1995 18:53:00 -0700
Organization: University of Michigan Chemistry Department, Ann Arbor
Lines: 73
Sender: biohelp@net.bio.net
Approved: comp-bio-moderator@net.bio.net
Distribution: world
Message-ID: <3qshir$dgp@srvr1.engin.umich.edu>
NNTP-Posting-Host: net.bio.net
Xref: biosci bionet.general:15613 bionet.biology.computational:665 bionet.biophysics:967 bionet.info-theory:3407 bionet.molbio.evolution:2954 bionet.molec-model:418 bionet.software:12271 sci.bio.evolution:3035 bionet.molbio.bio-matrix:585


                      Announcement and Call for Papers

                  THE EVOLUTION OF BIOMOLECULAR STRUCTURES 
                AND THE STRUCTURE OF BIOMOLECULAR EVOLUTION

                          A Seminar Track in the
                     Pacific Symposium on Biocomputing
                           January 3-6, 1996 
                        Ritz Carlton Hotel, Hawaii



  All biological macromolecules have an evolutionary origin that is 
manifested in essentially every aspect of their biological and 
physico-chemical properties. In order to 
understand these macromolecules, it is necessary to understand the 
relationship between these properties and the evolutionary pressures
that determined form and function.  
Information about the evolutionary history can be used to 
help predict the characteristics of these macromolecules.
Conversely, these macromolecules encode this evolutionary
heritage, and can provide insight into the 
process of molecular evolution. 

  Possible topics include:

  - Role of natural selection and self-organization in biomolecular evolution

  - The relationship between sequence and structure evolution

  - Structure-based evolutionary reconstruction

  - Definition, significance, and evolution of protein cores, loops, and
    other conserved motifs

  - Evolutionary interpretations of multiple sequence or structure alignments,
    including their use in biomolecular structure prediction

  - The exon theory of protein structural organization

  We welcome papers describing results from a wide range of possible
methodologies, including analyses of the databases of biomolecular 
sequences and structures, simple conceptual and computational 
evolutionary models, and experimental results.

  Current plans are for electronic publication of the papers by the MIT Press,
in both HTML and postscript.  People wishing to present posters without 
publishing a full paper may submit an abstract.  Preregistration for the
conference is required for the inclusion of a paper in the conference 
proceedings.

Paper submission deadline:                 July 27, 1995
Notice to authors:                         September 11, 1995
Final paper and preregistration deadline:  October 2, 1995


Richard A. Goldstein                     
Chemistry Department              
Biophysics Research Division   
University of Michigan
Ann Arbor, MI  48109-1055
(313) 763-8013
fax: (313) 747-4865
email: richardg@chem.lsa.umich.edu

Russ B. Altman
Section on Medical Informatics
Stanford University Medical Center, MSOB X-215
Stanford, CA 94305-5479
(415) 723-6979
fax: (415) 725-7944
email: altman@camis.stanford.edu 

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!swrinde!howland.reston.ans.net!ix.netcom.com!netnews
From: mrbrian@ix.netcom.com (brian sefton)
Newsgroups: bionet.jobs,bionet.software,comp.databases.oracle.comp.databases.informix,comp.databases.sysbase
Subject: Wanted: Prgrammers/applications for LIMS/Modeling
Date: 6 Jun 1995 22:37:20 GMT
Organization: Netcom
Lines: 13
Distribution: world
Message-ID: <3r2lb0$q09@ixnews2.ix.netcom.com>
NNTP-Posting-Host: ix-sj9-25.ix.netcom.com
Xref: biosci bionet.jobs:10127 bionet.software:12284

Inmartech is currently looking for programmers experienced in
biological/pharm research database work, including data aquisition a/d
conversion etc, on UNIX platforms. We are also interested in 
prgrammers who have written molecular modeling software, or other
types of graphical simulation. 


Please respond to this email if you are interested in learning more
about what we are doing.

Sincerely
B. Sefton
Inmartech

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bcm!news.msfc.nasa.gov!sol.ctr.columbia.edu!news.mindlink.net!vanbc.wimsey.com!scipio.cyberstore.ca!news.Direct.CA!usenet
From: p1d@Direct.CA (M. J. P.)
Newsgroups: bionet.software
Subject: Typing TUTOR NEEDED!
Date: 6 Jun 1995 20:53:08 GMT
Organization: Internet Direct Inc.
Lines: 7
Message-ID: <3r2f7k$bv5@stud.Direct.CA>
NNTP-Posting-Host: dyn-310.direct.ca
X-Newsreader: WinVN 0.92.6+


If anyone out there knows how I can get a program that will help improve
my typing speed and accuracy via the Internet, please let me know!

THANK YOU IN ADVANCE

email" p1d@Direct.Ca

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!rutgers!gatech!swrinde!pipex!oleane!jussieu.fr!nef.ens.fr!news!claros
From: claros@biologie.ens.fr (Manuel .G CLAROS)
Newsgroups: bionet.software
Subject: Re: helical wheel program
Date: Tue, 6 Jun 95 18:13:29 GMT
Organization: Dpt Biologie, Ecole Normale Superieure
Lines: 18
Message-ID: <claros.1152850049A@news.ens.fr>
References: <nveldhoe-3005951749470001@p17-22.dialup.uvic.ca> <3qo43q$d3m@news.ccit.arizona.edu>
NNTP-Posting-Host: lgmmac0.ens.fr
X-Newsreader: VersaTerm Link v1.1.1

bear@helium.gas.uug.arizona.edu (Soaring  Bear) wrote:

>> If
>>anyone has or knows of Mac freeware or shareware that can create these
>>schematic diagrams, please let me know

>        In the same vein, how about a unix version, please?

MitoProt can easily do helical wheels (more information in an older post
 in this group) even if this is not the final goal of this program.

             We'll always have Paris (Rick Blaine, Casablanca)
                          // \\          // \\  // \\        Un amigo es uno
Manuel G. CLAROS         \': | \\      // | :,\\': | \\      que lo sabe todo
Ecole Normale Superieure  \\ | | \\  // | | //  \\ | | \\    sobre ti y a
Genetique Moleculaire       \\ | :,\\': | //      \\ | :,\\  pesar de ello
46 rue d'Ulm                  \\ //  \\ //          \\ //    te quiere.
75230 Paris Cedex 05            claros@biologie.ens.fr         E. Hubbard

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!daresbury!trane.uninett.no!sunic!sunic.sunet.se!umdac!news
From: peterl@umdix.umdc.umu.se (Peter Lundberg)
Newsgroups: bionet.software
Subject: Re: helical wheel program
Date: 6 Jun 1995 16:46:16 GMT
Organization: Phys Chem, University of Umea, Sweden
Lines: 249
Sender: -Not-Authenticated-[5799]
Message-ID: <3r20oo$91o@studium.student.umu.se>
References: <nveldhoe-3005951749470001@p17-22.dialup.uvic.ca>
NNTP-Posting-Host: spinup.chem.umu.se
X-Posted-From: InterNews 1.0.6@spinup.chem.umu.se
Xdisclaimer: No attempt was made to authenticate the sender's name.

There is one for mac. It is one of several protein programs
collectively called MacProt or Plot.A. You can probably get it from
umich etc.

Hope this helps.

73, Peter

Ps. Here is the readme file:

"From:ORANGE::GOLD::WINS%"JMILLER%VXBIO.SPAN@STAR.STANFORD.EDU"
17-AUG-1990 13:30 To:GILBERTD Subj:plota.readme file  Return-Path:
<@STAR.STANFORD.EDU:JMILLER@VXBIO.SPAN> Received: from
STAR.STANFORD.EDU by gold.ucs.indiana.edu with SMTP ;  Fri, 17 Aug 90
13:36:34 EST Received: from VXBIO by STAR.STANFORD.EDU via MAIL-11 with
DECnet; Fri,   17 Aug 90 11:24:25-PST Date: Fri 17 Aug 90 11:24:24-PST
From: JMILLER%VXBIO.SPAN@STAR.STANFORD.EDU Subject: plota.readme file
To: "24986::""GilbertD@Gold.Bacs.Indiana.edu"""@VXBIO.SPAN  
Notes on the compiled versions of the MacPROT package (Peter 
Markiewicz, 1990)  MACPROT MACProt consists of a set of programs for
analyzing protein  sequences for secondary structure, chain
flexibility, hydropathy,  helical wheels, and so on. Each program is
supplied in a separate  archive file. A list of the programs is given
below.  These notes on the MacPROT package (compiled) are adapted  from
the original instructions for the interpreted MS basic versions. 
Changes have been made to reflect the differences between the  compiled
and interpreted versions. A reference list will be given in a  later
version of this document.  Each compiled version is supplied with the
portion of the  original manual which covers it, and the general
descriptions in this  document.  A complete list of the programs (June
1990) is given  below.  Differences Between Complied and Interpreted
versions: The compiled versions are for 512k mac and up models. Note 
that the programs may have problems with unenhanced (64k ROM)  512k
macs. To run (simpler) versions of the programs on an "classic" 512k
mac, you need to get the interpreted versions of the programs  from
Angela Luttke, as well as the Microsoft Basic interpreter. The compiled
versions are (1)faster, (2)handle several input  file types, (3) Allow
printing of larger output pictures (up to 11", (4)  allow user control
of output file type, (5)allow user control of output  colors, which
will work with color output devices even if the mac has  a black and
white screen, and (6) improved mac interface and  behavior under
MultiFinder. Compiled versions run about 5-10 times  faster than the
interpreted versions.  Using 6-point Monaco The Plot/A programs will
use 6-point Monaco to output, if it is  available in the System Folder.
The font is supplied for installation.  Using the smaller font makes
the output charts easier to read.  Adding to the output picture The
user may add to the output drawing by clicking on it with the  mouse.
If a peak on a hydropathy plot is clicked, for example, the  program
will list the position in the protein that was clicked. This is  very
useful for finding interesting stretches in the peptide sequence.  The
numbers are added to output ONLY until the user saves the  output to
the Clipboard, or prints the result. After that, the user  cannot add
to the existing picture. The numbers are drawn in Monaco  9-point font
UNLESS you have installed Monaco 6-point in your  system folder. The
font is provided for installation with the MacPROT  package with the
compiled versions.  
Input File Formats The interpreted versions of the programs recognize a
specific  format, and have file errors if any other sequence file
format  (including plain sequence is used). The compiled versions are
more  flexible, and can handle the following formats: the original
MacPRot  format, plain sequence (no comments or numbers), Pearson
format,  EMBL format, GenBank format, and IntelliGenetics format. If
the file  contains more than one sequence in these formats, only the
first  sequence is loaded. In theory, files up to 32,000 amino acids
could be  loaded, but the practical limit is about 1000 amino acids.
All  programs were tested for function with up to 1000 amino acid
files.  The program uses TEXT or DNA Strider protein files only. If you
 type in your sequences with a word processor or other program, you 
will need to save your sequences in TEXT ONLY format. If you don't  do
this, you won't see your sequence when you press the "load file" 
button!  Consult the manual for your favorite word processor on how  to
save a sequence as a TEXT ONLY file. You CAN read protein files made
with DNA Strider. However, this format is tricky, and if you  write
comments in Strider, the PLOT/A programs won't be able to tell where
the sequence ends and the comments begin! If you must use Strider
files, either remove all comments.  MacPROT and MacDraw/MacPaint The
programs in the MacPROT package work create useful  output plots which
may be printed, or copied to the Clipboard using  File menu commands.
Once the output is copied to the Clipboard, you  may start either
MacDraw or MacPaint (or similar programs), and  paste the output graph
into a document. You can also paste directly  into your word processor,
but you will probably want to edit the  output chart somewhat before
doing this. In MacDraw, the object is pasted as a true collection of
draw  objects, rather than a bitmap, which allows you to customize it
by  color, font sizes, etc. MacDraw output prints at the resolution of
your  printer, 300dpi (dots per inch resolution) for a laserprinter,
and 72  dpi for an ImageWriter. You can also paste into a paint-type 
program, which will create a bitmap at 72dpi, and print at 72dpi  (even
with a LaserWriter!) Note that this copy/paste routine works with ALL
Mac  programs. That is, is you select "Copy" in any Mac program, load a
 new program, and select "Paste", the Copied result is pasted. This is 
an excellent way to move data between drawing programs and word 
processors. For example, after "cleaning up" a plot in MacDraw, you 
could select it, copy it, start MacWrite or MS word, and select Paste. 
The chart would become part of your word processing document.  Note
that very large protein sequences (>500-600 amino acids)  may exceed
the maximum allowed output picture size in some of the  programs. If
this happens, an alert warns the user to reduce the size  of the
sequence plotted. If this occurs, the best thing is to analyze  several
portions, copy the results, and paste each segment's results in  turn
into a single draw or paint document. This works especially well  with
MultiFinder. The complete set of programs are listed below.  MacPROT
programs listed under the menu 'Programs' in the given  order. MENUPROT
(NOT IN THE COMPILED VERSIONS!!!!) gives  an overview on the individual
programs and their tasks (not under  programs, but opened either from
the finder or from within the  programs by using 'CANCEL' or 'Exit' in
all other programs; see  below). It is a reminder on what the programs
are doing and helps in  deciding which program needs be opened for a
certain analysis. It is  useful for the starting user, who is not yet
familiar with what the  programs' names stand for. 
AA.DATAis for storing and revising a protein sequence. The  program
puts the sequence in the format, which is later used by the  analysing
programs. It can also be used for editing an already stored  sequence.
In addition to storing the plain sequence, an optional  comment as well
as data on amino acid frequency and molecular  weights are calculated
and written to the same file. 
PLOT.A/HYDanalyses the hydropathy (hydrophobicity/  hydrophilicity)
according to four published hydropathy scales of any  sequence stored
in AA.DATA file format.  The plot can be printed or  saved to the
clipboard for pasting it into a picture accepting program.  After the
plot is completed the same sequence can be analysed using  different
parameters and/or a different hydropathy scale. 
PLOT.A/HYD5analyses the hydropathy of a given sequence.  It calculates
and plots the hydropathy for  five increasing moving  averages (spans)
simultaneously. The first span and the step for the  increase is chosen
by the user. Saving and printing is done as in  PLOT.A/HYD. 
PLOT.A/SUMprovides three hydropathy plots for a single  sequence
simultaneously using three different hydropathy scales.  Saving and
printing is done as in PLOT.A/HYD. 
PLOT.A/H3calculates and plots the hydropathy of up to  three sequences
simultaneously. It can be chosen among four  hydropathy scales. Saving
and printing is done as in PLOT.A/HYD. PLOT.A/TMHcalculates and plots
the hydropathy. In  addition each value for the chosen span is
evaluated for its  coordinates in a 'hydrophobic moment' plot and the
corresponding  assignment to the helix type shown. The assignment is
also written to  a disk file in ASCII format. Saving and printing is
done as in  PLOT.A/HYD. 
PLOT.A/HELdraws a helical wheel of a user selected span  of amino
acids, plots the hydropathy, and calculates the mean  hydropathy using
two scales. Saving and printing is done as in  PLOT.A/HYD. 
PLOT.A/DOTplots two sequences (the same or different  ones) against
each other in a dot matrix. Two methods are used,  which either search
for perfect matches (identities) or for similarities  according to five
different score matrices based on (a) accepted point  mutations, (b)
genetic and structural similarities, (c) conformational  state, and (d)
observed substitutions. Saving and printing is done as  in PLOT.A/HYD. 
PLOT.A/GORcalculates and plots the preference of each  residue for four
conformations (helix, extended, coil, turn) along the  sequence. The
sequence is written to a file in coded letters according  to the most
likely preference. Saving and printing is done as in  PLOT.A/HYD. 
PLOT.A/GGRsimilarly calculates and plots the preference  for three
conformations (helix, extended, coil) along the sequence and  writes
the evaluation to a disk file. Saving and printing is done as in 
PLOT.A/HYD. 
PLOT.A/STRsearches for up to ten user selected stretches  of amino
acids within a given sequence and plots the respective  positions found
along the sequence. Saving and printing is done as in  PLOT.A/HYD. 
PLOT.A/FOTsuggests regions likely to be amphipathic.  Two disk files
are created (1) to specify the residue starting an  amphipathic
segment, and (2) to write the sequence in coded format.  Saving and
printing is done as in PLOT.A/HYD. 
PLOT.A/POWplots the power spectrum of a user selected  stretch. Saving
and printing is done as in PLOT.A/HYD. PLOT.A/KASdetermines main chain
flexibility and in turn  antigenic determinants. 
PLOT.A/TSLtranslates a DNA sequence.  
Paths among programs  Each program can be opened from the finder by
double-clicking on  the respective icon or by starting MENUPROT and
then choosing the  respective program from the menu bar under the
'Programs' menu.  From within the programs a different/same program can
be chosen  at any time during the run by pulling down the 'Programs'
menu.  A 'CANCEL' button in the first window provides the option to
leave  the program and go to 'MENUPROT'.  
There are two other ways of leaving a program during program 
execution, 'Exit' and 'Quit', via the 'File' menu (see sketch above),
which also contains the options for saving a plot to the clipboard or 
printing it on a dot matrix printer.  A "Help" button in the input
window summarizes program use  (briefly).  The 'File' menu  Note that
the File menu commands for Open and Save are  handled differently in
the MacPROT package.  The standard Open  command for an input file is
provided by the "load file" button, and  the programs prompt for the
name of an output file to Save if  necessary. 
Save to Clipsaves a plot to the clipboard for pasting it into  a
picture accepting program (graphs created by programs for this  manual
were saved to FullPaint). This option is available only after  the the
plot is finished. It is otherwise identical to the "Copy"  command
found under the Edit menu of most mac programs. At  other times during
program execution (loading a file, choosing  parameters, analysis) the
option is dimmed. If a plot is saved to the  Clipboard, you should quit
the program (Finder), or switch to the  program you want to paste to
(MultiFinder), and select Paste. It may  take several seconds, since
some of the plots are very complex for  the mac to draw!  Rerunning the
program immediately with the same  or different parameters erases the
current plot and creates a new  one.  
Print Pictureprints the plot to any printer. As with 'Save to  ...' the
option is available only after the plot is finished. The common  two
commands on paper size and printing options need be answered  before
printing starts. Note that MacPROT program can only draw a  singel page
of output, meaning the plot can't be more than 10 inches  to print. To
print a long plot, select the sideways "landscape" print  mode in the
Page Setup Window. 
QuickPrintNOTE:THIS WORKS ONLY WITH AN APPLE  IMAGEWRITER!!!! prints an
instant hardcopy of the screen on the dot  matrix printer (printer must
be on!) in 'Standard' quality. Though  similar to the 'Print Picture'
option in 'Standard', it's a quick print  facility omitting the
selection windows for paper format and print  quality. Exit closes all
files in memory (the running program as well as  textfiles created by
some programs) and goes to 'MENUPROT'. The  option is available all the
time during program execution. It is  particularly useful, if by
mistake the 'wrong' program was opened  and explanations about the
label for the 'right' program are required  (or a cup of coffee/tea is
needed in between?). Quit also closes all open files, but goes back to
the Finder  (done for the day!).  The Options Menu The compiled
versions of MacPROT have an Options menu,  where the user may change
the colors used in creating the output  graph, and the output file
type. Colors being currently used are listed  in the input window. The
color information is recorded even if you  have a black and white mac.
You can print in color to (1)an  ImageWriter II with a color ribbon,
(2)a HP PaintJet or other color  inkjet printer with a mac interface,
or (3)a color laserprinter. The file  type option sets the output file
format used in creating text output of  the calculations. When the
output file is clicked (it may be necessary  to open and close its
volume/folder first), the mac will use the  specified word processor to
open it. MacWrite,WriteNow, MS  Word,EDIT, and FORMAT are currently
supported. Access to Programs Compiled versions of these programs will
will become available  in 1990. They may be downloaded from the
following databases  using electronic mail or FTP over bitnet,
internet, or your local net if  it has a gateway. EMBL:   NETSERV@EMBL
GET MAC_SOFTWARE:filename.ext  IUBIO: IuBio.Bio.Indiana.Edu (IP name) 
129.79.1.101  (IP address)  U Houston:  genbank-server@bchs.uh.edu 
(INTERNET/ARPANET)  uhnix2!genbank-server  (usenet won't work for much 
longer) SEND MAC hqx-encoded-file-name  America Online: New service
summer 1990, consult your manual for  details send HELP messages to
find out how to download the programs.  from the various servers listed
above. They are also available on  floppies as part of a larger set of
public domain programs for  sequence analysis on the Macintosh from the
following address:  Peter Markiewicz Dept. Microbiology, MBI, UCLA Los
Angeles, CA 90024  To get them on floppy, you must  (1)send 15 800k
initialized floppies with blank labels. (2)Include a return enveloped,
addressed to you, with $2.40 postage  (US).  If one of the above is
lacking, the programs won't be sent. It  normally takes me 2-4 months
to process requests.  Note that you can get the programs MUCH faster by
using electronic  mail and/or online databases listed above. A tutorial
on how to use  electronic mail and online databases is available as a
HyperCard stack from the above address.  "

O==O ================================== O==O
O==O Peter Lundberg                     O==O
O==O Email: peterl@umdix.umdc.umu.se    O==O
O==O ============761.91141============= O==O

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!xlink.net!rz.uni-karlsruhe.de!news.uni-stuttgart.de!news.belwue.de!news.belwue.de!newsserv.zdv.uni-tuebingen.de!local!uwe.schueler
From: uwe.schueler@uni-tuebingen.de (Uwe Schueler)
Newsgroups: bionet.software
Subject: KEITHLEY TESTPOINT FILES WANTED
Date: Tue, 6 Jun 1995 16:02:54
Organization: Elektroniklabor Physiologie
Lines: 4
Message-ID: <uwe.schueler.13.00100CD6@uni-tuebingen.de>
NNTP-Posting-Host: elab.physiologie.medizin.uni-tuebingen.de
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

I'm looking for the files      TP11D1.zip
                                           TP11D2.zip
                                           TP12947.zip
does a KEITHLEY FTP-server exist or could somebody email them uuencoded ?

From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!ief.spb.su!spin
From: spin@ief.spb.su (Alexandr Spirov)
Newsgroups: bionet.software
Subject: Re: Promoter region sequence analysis
Date: 6 Jun 1995 08:51:39 -0700
Organization: Inst. of Evolutionary Physiology & Biochemistry,
    St.Petersburg
Lines: 80
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <AA9e5rliI8@ief.spb.su>
References: <AAKRUmliI8@ief.spb.su>
NNTP-Posting-Host: net.bio.net

     This is news-message from my archive (Newsgroups:
bionet.molbio.genome-program).
     To my mind, Brian Foley's comments is good illustration
of situation in the field under discussion.  In other word, if
you have unique newly sequencised gene (especially if by your own hands),
then we will do all the work with enthusiasm. But if you interesting
in treatment and comparisons of multigene (multiKB) DNA blocks,
then such preferably hand-made search & analysis became impracticable.

          Alexander Spirov.



---------------------------------------------------------------------------
>Date: Wed, 23 Nov 1994 03:48:03 GMT
>From: brianf@med.uvm.edu (Brian Foley)
>Message-Id: <1994Nov23.034803.21069@emba.uvm.edu>
>Organization: EMBA Computer Facility, University of Vermont
>Newsgroups: bionet.molbio.genome-program
>Subject: [NEWS] Re: sequence comparison
>Status: O

>Giltsu Choi (tchoi@binah.cc.brandeis.edu) wrote:
>: I have 2kb upstream of A gene from two related species
>: and 2kb upstream of B gene from a species. B gene is
>: coordinately regulated with A gene in terms of
>: expression pattern. Now I want to do some sequence
>: comparisons to extract information such as
>: possible sequence elements for the regulation of these genes.

>        Are we talking eukaryotic or prokaryotic?  If eukaryotic:

>        First look at the Eukaryotic Promoter Database to see if
>any previously desribed promoter elements are present in the
>upstream regions of gene A and gene B.
>        This will also show you the types of sequences that have
>been found to have regulatory activity.  You will find that
>such promoter elements as the glucocoricoid response element (GRE)
>are quite short sequences of 6-12 bases, often palindromic
>or semi-palindromic but sometimes asymetrical.

>        This tells you that you will not be looking for big regions
>of 20 to 50 bp of similarity in the promoters of A and B, so when you
>do an alignment of the two promoters, you want to use an algorithm that
>will find short segments of similarity among a lot of background "noise"
>of non-similar sequence.  A dot-plot type of program is good for this
>a small window size, but perhaps a high stringency (like use a window
>of 5 and only plot a point when 4 or 5 bases in the window are
>perfect match between A and B).
>        Also dot-plot each against itself, because many promoter elements
>turn up in repeated arrays in promoters.

>        None of this is going to PROVE that the sequences you find
>in common between A and B are actually involved in promoter activity.
>You will have to do some deletions or site-directed mutations of each
>promoter, linked to a reporter gene to prove that the elements
>you identify have biological function.
>        On the other hand, if you have good evidence already that
>these two genes are activated by a common signal, and you find
>copies of previously reported promoter elements that also appear
>in other genes which respond to that signal, you have a pretty good
>bet that you have identified significant elements.

>        Protein sequence similarities often span large regions and
>are highly conserved throughout whole kingdoms.  But promoter elements
>are much more difficult to identify.  They are short regions.  They can
>be variable distances from the start codon.  They can have variable
>spacing between repeats.  Some genes are tightly regulated and have
>highly conserved promoters, but others do not.

>        Let us know what you find.


>********************************************************************
>*  Brian Foley               *     If we knew what we were doing   *
>*  Molecular Genetics Dept.  *     it wouldn't be called research  *
>*  University of Vermont     *                                     *
>********************************************************************
>


From owner-software@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!news.sprintlink.net!demon!uknet!strath-cs!st-and!Aberdeen!gen125
From: gen125@abdn.ac.uk (p.metcalfe)
Newsgroups: bionet.software
Subject: Wanted: DGGE Software
Date: 6 Jun 1995 06:49:14 GMT
Organization: University of Aberdeen,  Scotland
Lines: 16
Message-ID: <3r0tpa$qgf@nof.abdn.ac.uk>
NNTP-Posting-Host: bio.if2.abdn.ac.uk
X-Newsreader: TIN [version 1.2 PL2]

Does anyone know where I can get hold of sofware for predicting melting domains
during Denaturing Gradient Gel Electrophoresis (DGGE), knowing the sequence of
the duplex to be analysed.

I know of a programme called MELT, is there an FTP site for this software ??

Please reply by email.

Paul Metcalfe
Department of Molecular and Cell Biology
University of Aberdeen
Scotland
UK

Email: gen125@abdn.ac.uk


From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!elroy.jpl.nasa.gov!swrinde!howland.reston.ans.net!Germany.EU.net!EU.net!news.sprintlink.net!uunet!in1.uu.net!svc.portal.com!portal.com!cup.portal.com!Zekeman
From: Zekeman@cup.portal.com (Enrico Ami-tox gilberti)
Newsgroups: bionet.software
Subject: ImageCalc location ?
Date: 6 Jun 1995 20:20:04 -0700
Organization: The Portal System (TM)
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Sender: pccop@unix.portal.com
Message-ID: <139990@cup.portal.com>
NNTP-Posting-Host: news1.unix.portal.com

I am looking for a site where i can get the shareware program 
called ImageCalc.  Anyone help ?

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!daresbury!trane.uninett.no!Norway.EU.net!EU.net!howland.reston.ans.net!spool.mu.edu!uwm.edu!msunews!thomashaw-at.css.msu.edu
From: bloksber@pilot.msu.edu  (Leonard N. Bloksberg)
Newsgroups: bionet.software
Subject: Programming language querry
Date: Tue, 06 Jun 1995  23:51 EDT
Organization: Michigan State U., Crop & Soils Dept.
Lines: 13
Distribution: world
Message-ID: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
NNTP-Posting-Host: thomashaw-at.css.msu.edu
X-Newsreader: FTPNuz (DOS) v1.0

I'm getting sick of waiting for some specialized applications to be written
for me, so I'm entertaining the idea of writing my own programs.  I am 
comfortable in DOS and UNIX, but I only have access to DOS and Windows 
machines right now.  I'm leaning toward a C language because I understand 
that programs can be compiled for UNIX, DOS, or MAC from the same code.
Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
something that will be both easy to pick up, and powerfull enough to bother 
spending time to learn?  Thanks.
.
Lenny Bloksberg
bloksber@pilot.msu.edu
.
.

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!uwm.edu!msunews!thomashaw-at.css.msu.edu
From: bloksber@pilot.msu.edu  (Leonard N. Bloksberg)
Newsgroups: bionet.software
Subject: Re: GCK for PCs???
Date: Tue, 06 Jun 1995  23:42 EDT
Organization: Michigan State U., Crop & Soils Dept.
Lines: 20
Distribution: world
Message-ID: <19950606234237.bloksber@thomashaw-at.css.msu.edu>
References: <1995Jun6.114911@ania.path.ox.ac.uk>
NNTP-Posting-Host: thomashaw-at.css.msu.edu
X-Newsreader: FTPNuz (DOS) v1.0

In Article <1995Jun6.114911@ania.path.ox.ac.uk> "enriquez@molbiol.ox.ac.uk (PITA ENRIQUEZ HARRIS)" says:
> Dioes anyone know if there are any plans to do a version of Gene Construction 
> Kit for PCs?  Its a terrific Mac program, but I have a PC at home.
> 
> Thanks ,
> 
> Pita
> 
> 
Clone is a very similar program that runs on PC.  Both GCK and Clone are 
nearly identicle, both have minor pros/cons against the other, and both are
radically overpriced at around $1000- to $1500-.  Neither program allows any
file conversion to trade files between programs on the same machine, never 
mind different platforms.  All this was correct as far as I could tell, about
a year ago when I last looked the 2 programs over.  I know of no other 
programs that come close to these 2.
Lenny Bloksberg
bloksber@pilot.msu.edu
.
.

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!uwm.edu!msunews!harbinger.cc.monash.edu.au!newshost.anu.edu.au!newsmaster
From: johna@rsbs-central.anu.edu.au
Newsgroups: bionet.software
Subject: RAPD data analysis - software
Date: 7 Jun 1995 02:08:52 GMT
Organization: rsbs - anu - Australia
Lines: 20
Message-ID: <3r31nk$j0o@manuel.anu.edu.au>
NNTP-Posting-Host: 150.203.38.97
X-Newsreader: <WinQVT/Net v3.9>

                RAPDistance Package
A group at the Research School of Biological Sciences, Australian
National University, Canberra under the direction of Prof. Adrian Gibbs 
has developed a software package called RAPDistance for the analysis of 
RAPD data. It has a comprehensive range of options for creating data 
files, editing them and using application programs to analyse them. 
The third version has just been released on the Internet. The first 
version was made available in October 1994. It is intended to maintain 
and extend the package as resources allow.
The following files are available :-
1) README.DOC  Getting started.
2) INTRO.DOC   Brief details of scope of package and modifications.
3) RAPD103.EXE Self extracting archive file containing the package.

Accessed from the Internet via :-
1) Anonymous ftp ftp://life.anu.edu.au/pub/RAPDistance
or 2) WWW http://life.anu.edu.au/molecular/software/rapd.html

Please register with me if you use the package so that I can keep you
informed of new versions, bugs etc. Regards. John Armstrong

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!swrinde!pipex!oleane!jussieu.fr!jouy.inra.fr!butler
From: butler@jouy.inra.fr (Philip Butler)
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 1995 11:56:24 GMT
Organization: INRA
Lines: 17
Message-ID: <3r4458$mom@saphir.jouy.inra.fr>
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu> <3r3m5v$jpn@saphir.jouy.inra.fr> <1995Jun7.111611.66218@ucl.ac.uk>
NNTP-Posting-Host: diamant.jouy.inra.fr
X-Newsreader: TIN [version 1.2 PL2]

Rob Miller (rmiller@bsm.bioc.ucl.ac.uk) wrote:
:   I suggest you also take a look at Tcl/Tk, a script language with ...
Thanks for correcting the omission on my part.

: If you run into anything that's too 
: numerically intensive, it's trivial to extend the interpreter with new 
: commands written in C or C++.
APL simply provides a fine efficient way of extending the scripting approach
to many number crunching problems.

What I like about Unix is that you can pick the language that is best adapted
to each specific task and then combine all the pieces of software together.
This is extremely difficult to do with DOS (as I found out the hard way...).
--
 /WWW\ Philip BUTLER			e-mail: butler@jouy.inra.fr
 |o,o| INRA/UCD/Service Linguistique	tel:	(33.1) 34.65.24.54
 \_=_/ F-78352 Jouy-en-Josas Cedex	fax:	(33.1) 34.65.22.72

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!pipex!uknet!bcc.ac.uk!rmiller
From: rmiller@bsm.bioc.ucl.ac.uk (Rob Miller)
Subject: Re: Programming language querry
Message-ID: <1995Jun7.111611.66218@ucl.ac.uk>
Date: Wed, 7 Jun 1995 11:16:11 GMT
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu> <3r3m5v$jpn@saphir.jouy.inra.fr>
Organization: University College London
X-Newsreader: TIN [version 1.2 PL2]
Lines: 49

Leonard N. Bloksberg (bloksber@pilot.msu.edu) wrote:
: I'm getting sick of waiting for some specialized applications to be written
: for me, so I'm entertaining the idea of writing my own programs.  I am 
: comfortable in DOS and UNIX, but I only have access to DOS and Windows 
: machines right now.  I'm leaning toward a C language because I understand 
: that programs can be compiled for UNIX, DOS, or MAC from the same code.
: Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
: something that will be both easy to pick up, and powerfull enough to bother 
: spending time to learn?  Thanks.

 
  I suggest you also take a look at Tcl/Tk, a script language with 
interpreters available for Unix (where it started), Windows, maybe DOS,
and probably MAC (I just do the Unix stuff, sometimes see notes about
interpreters for other systems and comments about it being the `language
of the internet' because of it's portability).  It's quick to learn, 
powerful enough to do most things, very rapid for generating complete 
applications, and the Tk toolkit makes all the graphics and GUI stuff 
*very* easy and straightforward.  If you run into anything that's too 
numerically intensive, it's trivial to extend the interpreter with new 
commands written in C or C++.  There's a tcl newsgroup, comp.lang.tcl, 
and at least one book, _Tcl and the Tk Toolkit_ by John Ousterhout 
(isbn 0-201-63337-X), and it is public domain.


						rob.

  

--
-------------------------------------------------------
Rob Miller, Ph.D.  

Biomolecular Structure and Modelling Unit (BSM),
Department of Biochemistry and Molecular Biology,
University College / Gower Street / London WC1E 6BT.
United Kingdom.

Tel: +44 171419 3896 
Fax: +44 171380 7193

Internet: rmiller@bsm.bioc.ucl.ac.uk
http://www.biochem.ucl.ac.uk/~rmiller
-------------------------------------------------------






From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!rutgers!uwm.edu!cs.utexas.edu!news.sprintlink.net!pipex!uknet!bcc.ac.uk!dac159!dcurtis
From: dcurtis@hgmp.mrc.ac.uk (David Curtis)
Subject: Re: Programming language querry
Sender: news@ucl.ac.uk (Usenet News System)
Message-ID: <dcurtis.191.000BD15F@hgmp.mrc.ac.uk>
Date: Wed, 7 Jun 1995 10:48:59 GMT
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu> <3r3j7a$fge@lyra.csx.cam.ac.uk>
Organization: Institute of Psychiatry
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]
Lines: 45

Wow, great! Now we can have language flames in bionet.software.

Just to say:

In article <3r3j7a$fge@lyra.csx.cam.ac.uk> tjrc1@mole.bio.cam.ac.uk (Tim Cutts 
(Zoology)) writes:>Path: 
bcc.ac.uk!uknet!plug.news.pipex.net!pipex!lyra.csx.cam.ac.uk!mole.bio.cam.ac.uk
!tjrc1>From: tjrc1@mole.bio.cam.ac.uk (Tim Cutts (Zoology))>Newsgroups: 
bionet.software>Subject: Re: Programming language querry
>Date: 7 Jun 1995 07:07:22 GMT
>
>Consider carefully what sort of program you wish to write.  Are you
>going to be dealing with large memory structures (>64k)?

>If so, you will find that DOS and Windows are a pain to develop on,
>since even in 386 Enhanced mode, Windows deals with memory in 64k
>chunks, which is a pain to work around.  DOS is even worse, although
>there are now 32bit DOS extenders, but I can't speak for these at all.

I can speak for 32bit DOS extenders and they work fine. I've got the Symantec 
compiler and one can allocate big chunks of memory using the 32bit memory 
model, but you can't debug these applications. Windows is better than DOS use 
to be because you get access to virtual memory, so needing lots of memory 
isn't a problem provided you only want not-huge chunks. And the free C++ 
compiler, g++, is available for 32bit DOS as well as OS/2 and Unix and again 
this works fine.The FASTLINK linkage programs for DOS have been compiled with 
this and they use large memory structures and run perfectly well and quite 
quickly. So, if you like DOS/Windows then I think they offer a perfectly 
reasonable development environment for many applications. 

PS I agree with the choice of languages: go for C/C++. Try to avoid using the 
Borland-specific extensions if you want to ever be able to port your software 
to another system, and remember that if you want other people to be able use 
it then you should really consider Unix as a target as well. Personally, I do 
all my development work with DOS/Windows but aim to produce code I will be 
able to port to Unix. For progs with GUIs I use the (free) wxWindows library 
which produces applications that run under Windows and X. I expect this would 
be slightly harder to get started with than visual C++ though. It just depends 
whether portability is an issue for you. 

Good luck anyway.


Dave Curtis (dcurtis@hgmp.mrc.ac.uk)
http://www.iop.bpmf.ac.uk/home/depts/psychmed/general/dcurtis/dcurtis.htm

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!elroy.jpl.nasa.gov!swrinde!howland.reston.ans.net!Germany.EU.net!nntp.gmd.de!news.rwth-aachen.de!news.rhrz.uni-bonn.de!news.uni-stuttgart.de!news.belwue.de!news.belwue.de!News.Uni-Marburg.DE!news.th-darmstadt.de!fauern!winx03!wrzx15!phak004
From: phak004@wrzx15.rz.uni-wuerzburg.de (Cornelius Krasel)
Newsgroups: bionet.software
Subject: Re: Mac PostScript converter/viewer
Date: 6 Jun 1995 19:01:57 GMT
Organization: University of Wuerzburg, Germany
Lines: 33
Message-ID: <3r28n5$5pf@winx03.informatik.uni-wuerzburg.de>
References: <3qlcd7$1us@nnrp.ucs.ubc.ca>
NNTP-Posting-Host: wrzx15.rz.uni-wuerzburg.de
X-Newsreader: TIN [version 1.2 PL2]

Alex Chang (lpss@unixg.ubc.ca) wrote:
> I am looking for a Mac PostScript converter or viewer, in order to read 
> PostScript files using Mac computer. I'll appreciate if someone could 
> provide that information, esp. a noncommercial program.

There are several possibilities:

You can print Postscript files directly on a LaserWriter if you have
the LaserWriter Utility available. This works for all Postscript laser
printers; I am not sure if it is also possible with non-laser printers
like a style writer. The LaserWriter Utility comes with every Apple
Laser Writer. If you have another printer, like an HP Laserjet, the
company should provide some equivalent software (as HP does).

You can use Ghostscript. I have no experience with it on a Mac.

Several drawing programs are able to display Postscript and let you even
manipulate it. These are all programs which are able to read Adobe
Illustrator files. Adobe Illustrator format seems to be a "light"
version of Postscript. There is a program called EPSconverter (free-
or shareware, can'€t remember) which converts "normal" Postscript in
a format which is readable by Adobe Illustrator. (WARNING: even on a
PowerMac it is no fun to work with a Postscript file with 1000+ objects.)

AFAIK, some graphics converters are able to convert EPS to GIF or whatever
pixel format you would like.

--Cornelius.

--
/* Cornelius Krasel, Institut f. Pharmakologie, Versbacher Str. 9, D-97078 */
/* Wuerzburg, Germany                email: phak004@rzbox.uni-wuerzburg.de */
/* "Science is the game you play with God to find out what His rules are." */

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!cs.utexas.edu!howland.reston.ans.net!pipex!oleane!jussieu.fr!jouy.inra.fr!butler
From: butler@jouy.inra.fr (Philip Butler)
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 1995 07:57:51 GMT
Organization: INRA
Lines: 40
Distribution: world
Message-ID: <3r3m5v$jpn@saphir.jouy.inra.fr>
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
NNTP-Posting-Host: diamant.jouy.inra.fr
X-Newsreader: TIN [version 1.2 PL2]

Leonard N. Bloksberg (bloksber@pilot.msu.edu) wrote:
: I'm getting sick of waiting for some specialized applications to be written
: for me, so I'm entertaining the idea of writing my own programs.  I am 
: comfortable in DOS and UNIX, but I only have access to DOS and Windows 
: machines right now.  I'm leaning toward a C language because I understand 
: that programs can be compiled for UNIX, DOS, or MAC from the same code.
: Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
: something that will be both easy to pick up, and powerfull enough to bother 
: spending time to learn?  Thanks.

C and C++ are good for writing middleware, i.e. code that is worth spending a
lot of time on because it will run very frequently and every clock cycle 
that you can save is worth saving.  C and C++ can be considered as 'portable
assembly language'.

If you are an ordinary scientist, you probably want to program in
problem-space (in terms of molecules, plants etc..) rather than cyber-space
(bits and bytes).  Among 3rd generation languages, Ada (and Oberon?) is much
closer to problem-space than C++ is.  Another language that I find extremely
useful is APL.  Computer illeterate people can start doing useful things with
it within a day and it is perfect for power users.  Unix shell scripts and APL
have more or less the same philosophy and suit me fine.
Check out in the 'APL Quote Quad' and 'Vector' journals whether APL will
suit you.  A good server for APL is ftp://wuvieai.wu-wien.ac.at
The appropriate newsgroup to browse through is comp.lang.apl

Other languages that may be worth considering are Smalltalk, Lisp and Forth, 
but I am less acquainted with these.  Prolog is great for some specific
problems.

I suspect software vendors try and make all end users use C++ because it will 
never match their requirements and will always have to spend more money.
Ada and APL have their own ISO standards and are as safe as you can get in
terms of portability.

Just trying to show that APL fans can be open-minded too!
--
 /WWW\ Philip BUTLER			e-mail: butler@jouy.inra.fr
 |o,o| INRA/UCD/Service Linguistique	tel:	(33.1) 34.65.24.54
 \_=_/ F-78352 Jouy-en-Josas Cedex	fax:	(33.1) 34.65.22.72

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!elroy.jpl.nasa.gov!swrinde!pipex!lyra.csx.cam.ac.uk!mole.bio.cam.ac.uk!tjrc1
From: tjrc1@mole.bio.cam.ac.uk (Tim Cutts (Zoology))
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 1995 07:07:22 GMT
Organization: University of Cambridge, England
Lines: 54
Message-ID: <3r3j7a$fge@lyra.csx.cam.ac.uk>
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
NNTP-Posting-Host: mole.bio.cam.ac.uk

bloksber@pilot.msu.edu  (Leonard N. Bloksberg) writes:

>I'm getting sick of waiting for some specialized applications to be written
>for me, so I'm entertaining the idea of writing my own programs.  I am 
>comfortable in DOS and UNIX, but I only have access to DOS and Windows 
>machines right now.  I'm leaning toward a C language because I understand 
>that programs can be compiled for UNIX, DOS, or MAC from the same code.
>Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
>something that will be both easy to pick up, and powerfull enough to bother 
>spending time to learn?  Thanks.

Yes, as long as you use it to compile DOS programs only.  Windows
programs will *not* be easily portable to anything else (and they're
much harder to write anyway).

Consider carefully what sort of program you wish to write.  Are you
going to be dealing with large memory structures (>64k)?

If so, you will find that DOS and Windows are a pain to develop on,
since even in 386 Enhanced mode, Windows deals with memory in 64k
chunks, which is a pain to work around.  DOS is even worse, although
there are now 32bit DOS extenders, but I can't speak for these at all.

If you will be needing large data structures, you are much better off
using a 32bit operating system, where you can happily say 'give me 3Mb
now' and it will (provided you have enough memory).  At the moment
this means Windows NT, OS/2 or Unix.

In the case of OS/2 and Unix, there is a free C++ compiler available
(gcc), which is perfectly serviceable.  It is rather more stable (in
my experience) under Unix than OS/2, which is hardly surprising, since
Unix is where it came from.  I understand gcc for NT is being
developed but is not yet available.

The advantage of gcc is that it is free.  The disadvantage (in my
opinion) is that although GNU software is pretty functional, it does
not have the ease of use and excellent debugging tools that are found
in commercial compilers like Borland C++.

Incidentally, Borland C++ is also available for OS/2.

Here's my advice in a nutshell:

1) Assess what sort of program you need to write.
2) If it's going to involve large amounts of data in memory, think
   seriously about using a 32bit OS - Unix may be a pain in the
   backside to use, but it's a joy to write programs for.
3) If compatibility is a major issue, NT is probably the OS, to go
   for, but development tools are expensive.
4) If compatibility with DOS/Windows is not an issue, setting up a
   small Linux system on one of your PCs with gcc is probably a better
   bet.

Tim.

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!howland.reston.ans.net!Germany.EU.net!EU.net!news.sprintlink.net!uunet!zib-berlin.de!news.rrz.uni-hamburg.de!news
From: Reski@botanik.uni-hamburg.de (Sven Kruse)
Newsgroups: bionet.software
Subject: TrueType fonts
Date: 6 Jun 1995 09:08:05 GMT
Organization: Uni Hamburg
Lines: 2
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NNTP-Posting-Host: moses.botanik.uni-hamburg.de
X-Newsreader: <WinQVT/Net v3.9>

I am looking for Windows TrueType fonts with signs for "male" and "female". 
Thanks in advance           Sven 

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!elroy.jpl.nasa.gov!swrinde!pipex!news.sprintlink.net!sjuvm!zhltphs
Nntp-Posting-Host: 149.68.2.20
Date: Tue, 6 Jun 1995 16:21:07 -0400
From: "Trombetta, Louis D" <ZHLTPHS@sjumusic.stjohns.edu>
Newsgroups: bionet.software
Subject: imagecalc
Message-ID: <06JUN95.17649728.0122@sjumusic.stjohns.edu>
Sender: usenet@sjumusic.stjohns.edu
Organization: St. John's University
Lines: 16

hi
Does anyone have access to Imagecalc.
Are there any sites where it can be found?

Thanks

     *******************************************
     | Louis D. Trombetta, Ph.D.               |
     | Professor                               |
     | Department of Pharmaceutical Sciences   |
     | St. John's University                   |
     | 8000 Utopia Parkway                     |
     | Jamaica, N.Y. 11439                     |
     | 718 990 6025                            |
     | zhltphs@stjohns.edu            |
     *******************************************

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!spool.mu.edu!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!agate!msunews!netnews.upenn.edu!hmivax!bailey
From: bailey@genetics.upenn.edu (Charles Bailey)
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 95 11:32:03 EDT
Organization: HHMI/Human Genetics, Univ of Pa.
Lines: 42
Distribution: world
Message-ID: <1995Jun7.113203@hmivax>
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
NNTP-Posting-Host: hmivax.humgen.upenn.edu

In article <19950606235137.bloksber@thomashaw-at.css.msu.edu>, bloksber@pilot.msu.edu  (Leonard N. Bloksberg) writes:
> machines right now.  I'm leaning toward a C language because I understand 
> that programs can be compiled for UNIX, DOS, or MAC from the same code.
> Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
> something that will be both easy to pick up, and powerfull enough to bother 
> spending time to learn?  Thanks.

If you're interested in writing fast code, and are willing to spend time
developing it, then C is a reasonable choice.  As long as you stick to
ANSI-compatible constructs, your data-crunching code should be portable to
wide variety of systems.  If you want to perform I/O beyod simple byte-stream
files (especially involving a terminal or window), then you'll probably have to
use platform-specific extensions, but you can isolate these in a set of
routines which change from machine to machine and insulate the underyling code
from the environment.  If you can afford it, I'd recommend getting a C compiler
with a good debugger, since there's little that can replace actually tracing
the execution of problem code (IMHO).

As long as people are plugging their favorite "high-level" language, I'd
suggest you have a look at Perl as well.  Its control syntax is much like C, so 
it's relatively easy to switch back and forth.  It has intrinsic numeric and
string data types, and automatically handles type conversions, memory
management, and many of the other 'housekeeping' activities you've got to code
into a C program.  It runs on a very broad range of systems, so Perl programs
are likely to port well (again assuming that you haven't made extensive use of
calls out to the OS.  It's slower than C -- it's a semi-interpreted language --
but is still quite efficient, and there's a nice interface to external C
routines which allows you to implement the parts of your algorithm that need
to fly in C and converse easily with Perl.  It has a large community developing
both the language itself and task-specific extensions.  Finally, it's free.
Sounds pretty nice, no? :-)  It's not the solution to all your problems, but
we've found it very good for general-use procedural programming.

                    Regards,
                    Charles Bailey
--
!-------------------------------------------------------------------------------
!              Computational Biology and Informatics Laboratory
!         Dept. of Genetics, Univ. of Pennsylvania School of Medicine
!              Philadelphia, PA USA 19104     Tel. (215) 573-3112
!                    Internet: bailey@genetics.upenn.edu
!-------------------------------------------------------------------------------

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!daresbury!is.bbsrc.ac.uk!winskill
From: winskill@bbsrc.ac.uk (Andy Winskill)
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 1995 15:34:24 GMT
Organization: Biotechnology & Biological Sciences Research Council
Lines: 13
Distribution: world
Message-ID: <3r4gu0$a43@is.bbsrc.ac.uk>
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu> <1995Jun7.124721.22510@emba.uvm.edu>
Reply-To: andy.winskill@bbsrc.ac.uk
NNTP-Posting-Host: arco7.cc.bbsrc.ac.uk
X-Newsreader: mxrn 6.18-16


I would suggest C++. I my experience if you've not done any programming before
then C++ is, possibly, much easier to pick up than C. It also gives you 
access to many publically avaiable class libraries. I'm pretty certain I've 
seen some molecular biology classes out there.

Cheers,
Andy
-- 
Andy Winskill 		     |	Computing Centre ,Biotechnology & Biological 
Andy.Winskill@bbsrc.ac.uk    |	Sciences Research Council, Harpenden, Herts. UK
_____________________________+_________________________________________________
"Diplomacy is the art of saying "nice doggy" until you can find a rock."

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!agate!news.Stanford.EDU!nntp-hub2.barrnet.net!news3.near.net!emba-news.uvm.edu!muskrat.uvm.edu!mosier
From: mosier@muskrat.uvm.edu (edo)
Subject: Re: Programming language querry
Message-ID: <1995Jun7.124721.22510@emba.uvm.edu>
Sender: news@emba.uvm.edu
Organization: EMBA Computer Facility, University of Vermont
X-Newsreader: TIN [version 1.2 PL2]
References: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
Date: Wed, 7 Jun 1995 12:47:21 GMT
Lines: 36

Leonard N. Bloksberg (bloksber@pilot.msu.edu) wrote:
[..]
: machines right now.  I'm leaning toward a C language because I understand 
: that programs can be compiled for UNIX, DOS, or MAC from the same code.
: Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
: something that will be both easy to pick up, and powerfull enough to bother 
: spending time to learn?  Thanks.

pretty much any version of C which will compile in an ANSI C mode would 
be quite portable...ANSI C++ is also portable, however, ANSI C compilers 
may get stuck on the code generated in C++ mode...in other words, ANSI 
C++ is an extension of ANSI C, and can compile ANSI C code in addition to 
its own grammer...ANSI C can not compile ANSI C++ specific code...

given a choice of C implementations, I would chose Borland for general 
programming...if you have specific needs (such as 486 optimization), you 
will want to read the packaging/advertising carefully...

C as a language is quite powerful, being what's known as a low level 
language...it's closer to the operating system than higher level 
languages, creating quick and powerful code...

as for C being easy to pick up: if you've done any programming at all, C 
will be an easy transition...even if you haven't, C is an excellent 
language to start with...there is a large assortment of fine books on 
learning C, from many different perspectives (such as for the Pascal 
programmer, for the DOS user, for the Mac user, for the complete 
beginner, etc)...you will find no shortage of literature...

good luck, and enjoy!
Og

-----
hiding backwards inside of me i feel so unafraid
annie, hold a little tighter i might just slip away
NIN

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: ebi.announce,ebi.servers,bionet.molbio.embldatabank,bionet.software
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!pipex!sunsite.doc.ic.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!jecop
From: jecop@ebi.ac.uk (Jeroen Coppieters)
Subject: Changes to EBI-FTP database directories
Sender: news@ebi.ac.uk (Mr news)
Message-ID: <D9t1Er.6Bp@ebi.ac.uk>
Date: Wed, 7 Jun 1995 13:28:03 GMT
Organization: European Bioinformatics Institute
X-Newsreader: TIN [version 1.2 PL2]
Lines: 48
Xref: biosci bionet.molbio.embldatabank:514 bionet.software:12297

**********************************************************************
Between June 16th & 19th 1995, the subdirectories of 
/pub/databases/protein_extras/
will be reorganized on ftp.ebi.ac.uk (ftp.embl-ebi.ac.uk)
**********************************************************************
On June 16th, a new entry will be created for all subdirectories that
are currently located in /pub/databases/protein_extras/
These new directories will be located one level higher in the directory tree
e.g. /pub/databases/protein_extras/hssp will become /pub/databases/hssp
On June 19th, the old locations in /pub/databases/protein_extras/
will dissappear


If you run a mirror process on any of the following directories then change
your scripts during the period  16-19 June

Affected directories:
/pub/databases/protein_extras/dssp
/pub/databases/protein_extras/fssp
/pub/databases/protein_extras/ftphelp.txt
/pub/databases/protein_extras/hssp
/pub/databases/protein_extras/misfolded
/pub/databases/protein_extras/models
/pub/databases/protein_extras/nrl3d
/pub/databases/protein_extras/pdb
/pub/databases/protein_extras/pdb_select
/pub/databases/protein_extras/puu
/pub/databases/protein_extras/ras

If you need more information, contact nethelp@ebi.ac.uk

Jeroen
--
==============================================================
         . O .                               Jeroen Coppieters
     . O O o   O .                            Software Support
   O O O O *o    O O          Jeroen.Coppieters@embl-ebi.ac.uk
  O O O O(   *o  )O O                     (or jecop@ebi.ac.uk)
  )O O O O   o*  O O(                         ++44 1223 494422 
  O O O O( o*    )O O
  )O O O O  *o   O O(                      EMBL Outstation EBI
  O O O O(   *o  )O O      (European Bioinformatics Institute)
  )O @ O O   o*  O O(                             Hinxton Hall
    O O O( o*   )O('                                   Hinxton
     ` O(   *o O  '                         Cambridge CB10 1RQ
         ` O '                                              UK
http://www.ebi.ac.uk
==============================================================

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!uunet!in1.uu.net!cis.ohio-state.edu!magnus.acs.ohio-state.edu!freenet.columbus.oh.us!not-for-mail
From: hcampbel@freenet.columbus.oh.us (H Campbell)
Newsgroups: bionet.software
Subject: Anatomy graphics
Date: 7 Jun 1995 16:17:34 -0400
Organization: The Greater Columbus Freenet
Lines: 13
Message-ID: <3r51gu$fmp@acme.freenet.columbus.oh.us>
NNTP-Posting-Host: acme.freenet.columbus.oh.us
Summary: How do I use raw graphics?
X-Newsreader: TIN [version 1.2 PL2]

   I have downloaded what is termed raw graphic data from the Visible Human
Data Set at the National Library of Medicine.  It is located at the FTP
site:  vhp.nlm.nih.gov   This material consists of digitized
cross-sections of an actual human and CAT/MRI data as well.
   
   I haven't the slightest idea how to view the material.  It isn't in any
format that my viewing programs or other graphics manipulation programs
can use, nor is it legible to a tutorial program I use. 
I would like to incorporate this material into tutorial programs for an 
anatomy course.  Any suggestions?

Lee Campbell


From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.general,sci.bio,bionet.software
Path: biosci!daresbury!trane.uninett.no!nntp.uio.no!nac.no!Norway.EU.net!EU.net!news.sprintlink.net!uunet!in1.uu.net!pipex!swrinde!elroy.jpl.nasa.gov!usc!math.ohio-state.edu!uwm.edu!vixen.cso.uiuc.edu!uchinews!news
From: rmoldwin@midway.uchicago.edu
Subject: Re: mRNA/cDNA sequence sites?
X-Nntp-Posting-Host: rmoldwin.bsd.uchicago.edu
Message-ID: <D9tFJn.E19@midway.uchicago.edu>
Sender: news@midway.uchicago.edu (News Administrator)
Organization: U. of Chicago Hospitals
X-Newsreader: <WinQVT/Net v3.9>
Date: Wed, 7 Jun 1995 18:33:23 GMT
Lines: 34
Xref: biosci bionet.general:15646 sci.bio:17102 bionet.software:12306

In article <3r4ous$76d@vixen.cso.uiuc.edu>, don@meibm25.cen.uiuc.edu (Don A. 
Walthers) writes:

>i'm trying to find a site that stores sequences without any spaces between
>a certain number of nucleotides. when i search the owl database at 
>www.gbd.org and pick the appropriate match any sequences available have
>spaces inserted every 10 NT for easier reading. i'd like to use a text 
>editor to search for restriction sites and other various sequences
>but the spaces would interfere. thanks for any info
>
>-- 
>|----------------------------------------------------------------------------|
>|Don Walthers  | don@uiuc.edu  | University of Illinois at UC - Microbiology |
>|http://www.cen.uiuc.edu/~don/ | Engineering Workstations - Site Operator    |
>|____________________________________________________________________________|

Hi Don:
     I wrote a small visual basic program to strip out spaces and numbers from 
GenBank and similar files.  If you want, I can E-mail you a copy (that is if 
you use Window.)

--Rich

^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^~^
Richard Moldwin, M.D., Ph.D.
Section of Pediatric Hematology/Oncology
University of Chicago Hospitals
Wyler Room C408,   MC 4060
5841 S. Maryland Ave., M/C 4060
Chicago, IL  60637

E-mail: rmoldwin@midway.uchicago.edu
Phone 312-702-6808
Fax     312-702-988

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.software
Path: biosci!daresbury!trane.uninett.no!nac.no!Norway.EU.net!EU.net!news.sprintlink.net!uunet!nih-csl!loglady.ninds.nih.gov!johnk
From: johnk@spasm.niddk.nih.gov (John Kuszewski)
Subject: Re: Programming language querry
Message-ID: <1995Jun7.180314.14586@alw.nih.gov>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Nntp-Posting-Host: spasm.niddk.nih.gov
Reply-To: johnk@spasm.niddk.nih.gov (John Kuszewski)
Organization: National Insts. of Health
References:  <19950606235137.bloksber@thomashaw-at.css.msu.edu>
Date: Wed, 7 Jun 1995 18:03:14 GMT
Lines: 42

In article <19950606235137.bloksber@thomashaw-at.css.msu.edu>, bloksber@pilot.msu.edu  (Leonard N. Bloksberg) writes:
|> I'm getting sick of waiting for some specialized applications to be written
|> for me, so I'm entertaining the idea of writing my own programs.  I am 
|> comfortable in DOS and UNIX, but I only have access to DOS and Windows 
|> machines right now.  I'm leaning toward a C language because I understand 
|> that programs can be compiled for UNIX, DOS, or MAC from the same code.
|> Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
|> something that will be both easy to pick up, and powerfull enough to bother 
|> spending time to learn?  Thanks.

Exactly what kind of custom program are you looking to write?
A little utility (like a customized pocket calculator), or 
a molecular dynamics program?  

How important is having a good (graphic) user interface?

How important is the PC/Mac/Unix portability?

For writing little utility programs, Tcl (for PC and Unix, but 
probably not Macs) is OK.  Visual Basic is *much* better, but only
runs on PCs (Windows or DOS).  

For writing really big programs, I advise you to talk to an 
expert.  Inexperienced people tend to do a poor job of the
initial organizing of a very large program.

-- 
                                   _____________
                                   |        ___/_
                                   |        |/  /
                                   --  /\  //  /--
                                   ||  ||  /  /||
                                   ||  || /  / ||
                                   ||  ||/  /  ||
John Kuszewski                     ||  |/  /|  ||      
johnk@spasm.niddk.nih.gov          ||  /  /||  ||
                                   \/ /  / ||  \/
that's MISTER protein G to you!     |/__/|      |
                                      /_________|

"Biophysics has driven me to an attitude of apocalyptic doom"
   --Frank Delaglio

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!daresbury!trane.uninett.no!nac.no!Norway.EU.net!EU.net!howland.reston.ans.net!vixen.cso.uiuc.edu!meibm25.cen.uiuc.edu!don
From: don@meibm25.cen.uiuc.edu (Don A. Walthers)
Newsgroups: bionet.general,sci.bio,bionet.software
Subject: mRNA/cDNA sequence sites?
Date: 7 Jun 1995 17:51:24 GMT
Organization: University of Illinois at Urbana
Lines: 12
Message-ID: <3r4ous$76d@vixen.cso.uiuc.edu>
NNTP-Posting-Host: meibm25.cen.uiuc.edu
Xref: biosci bionet.general:15645 sci.bio:17100 bionet.software:12304

i'm trying to find a site that stores sequences without any spaces between
a certain number of nucleotides. when i search the owl database at 
www.gbd.org and pick the appropriate match any sequences available have
spaces inserted every 10 NT for easier reading. i'd like to use a text 
editor to search for restriction sites and other various sequences
but the spaces would interfere. thanks for any info

-- 
|----------------------------------------------------------------------------|
|Don Walthers  | don@uiuc.edu  | University of Illinois at UC - Microbiology |
|http://www.cen.uiuc.edu/~don/ | Engineering Workstations - Site Operator    |
|____________________________________________________________________________|

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!daresbury!sunsite.doc.ic.ac.uk!uknet!bhamcs!news.ox.ac.uk!news
From: Geoff Barton <gjb@bioch.ox.ac.uk>
Newsgroups: bionet.software
Subject: Re: Programming language querry
Date: 7 Jun 1995 17:40:26 GMT
Organization: Laboratory of Molecular Biophysics
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References: <19950606235137.bloksber@thomashaw-at.css.msu.edu>
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bloksber@pilot.msu.edu  (Leonard N. Bloksberg) wrote:
>I'm getting sick of waiting for some specialized applications to be written
>for me, so I'm entertaining the idea of writing my own programs.  I am 
>comfortable in DOS and UNIX, but I only have access to DOS and Windows 
>machines right now.  I'm leaning toward a C language because I understand 
>that programs can be compiled for UNIX, DOS, or MAC from the same code.
>Is "Borland C++ 4.5 visual" a good language to dive into?  Can anyone recomend
>something that will be both easy to pick up, and powerfull enough to bother 
>spending time to learn?  Thanks.

I'd stick with C/C++ and keep close to the ANSI standard (at least for C).  You
may not want to distribute your programs now, but doubtless a friend or
colleague will want your code if it does something useful!  Writing in ANSI
C usually makes such portability easy. 

As to development under DOS/Windows I'd buy a compiler that includes a DOS
extender.  I've used the WATCOM 32 bit compiler.  I just took some big C
programs developed for Unix and recompiled under DOS without any problem.  The
Watcom compiler will also compile for OS/2 and NT and Windows.  So you have
some flexibility.  I think it is cheaper than the Symantec compiler, at least
it
was a couple of years ago when I bought my copy.  I wouldn't waste time trying
to write code that will run on 16bit PCs.  They are a dying breed.

Geoff.
----------------------------------------------------------------------------
Geoffrey J. Barton
Laboratory of Molecular Biophysics, University of Oxford
Rex Richards Building, South Parks Road, Oxford OX1 3QU, U.K.

email:  gjb@bioch.ox.ac.uk  Telephone: +44 1865 275368  Fax: +44 1865 510454 
anonymous: ftp://geoff.biop.ox.ac.uk         WWW: http://geoff.biop.ox.ac.uk
----------------------------------------------------------------------------


From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!daresbury!trane.uninett.no!nntp.uio.no!nac.no!Norway.EU.net!EU.net!howland.reston.ans.net!news.moneng.mei.com!news.ecn.bgu.edu!willis.cis.uab.edu!news.lsu.edu!unix1.sncc.lsu.edu!unix1.sncc.lsu.edu!not-for-mail
From: jtolan@tiger.lsu.edu (James Marvin Tolan)
Newsgroups: bionet.software
Subject: systat for windows
Date: 7 Jun 1995 14:08:41 -0500
Organization: Louisiana State University
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Anybody use Systat for windows??
If so, please send me the companies mailing address or phone number.  I 
used it at UT, but since leaving, I have caught hell trying to locate 
another copy of it.
Thanks
-JT


From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
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From: medmult@aol.com (MedMult)
Newsgroups: bionet.software
Subject: Re: Anatomy
Date: 7 Jun 1995 00:27:27 -0400
Organization: America Online, Inc. (1-800-827-6364)
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For neuroanatomy, check out Brainiac! at our Website:

http://www.webcom.com/~medmult

A demo is available through this site.

Shari Frick
Medical Multimedia Systems

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
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From: phak004@wrzx15.rz.uni-wuerzburg.de (Cornelius Krasel)
Newsgroups: bionet.software
Subject: Re: PDB importing to AutoCad 12
Date: 7 Jun 1995 20:41:34 GMT
Organization: University of Wuerzburg, Germany
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Roger Isaacson (risaacson@ucsd.edu) wrote:
> I have just had the first version of a LISP  routine programmed so we can 
> import Protein Data Bank files into AutoCad for 3D editing and doing fancier 
> publication drawing than is usually possible with most low end 3D molecular 
> graphics programs such as RasMol.  We would be interested in your comments and 
> are willing to share the routine with anyone interested.

I would be interested in some example output (since I don't have AutoCad
available). Have you ever looked at the output of render programs such
as the Raster3D suite? Maybe this pleases you more than RasMol drawings?

(Sorry, I am not familiar with other rendering packages such as ribbons
or setor due to the lack of an SGI and my lazyness to contact the authors
of the respective programs.)

--Cornelius.

--
/* Cornelius Krasel, Institut f. Pharmakologie, Versbacher Str. 9, D-97078 */
/* Wuerzburg, Germany                email: phak004@rzbox.uni-wuerzburg.de */
/* "Science is the game you play with God to find out what His rules are." */

From owner-software@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!uhog.mit.edu!news.mathworks.com!news.ultranet.com!news.sprintlink.net!howland.reston.ans.net!vixen.cso.uiuc.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.general,sci.bio,bionet.software
Subject: Re: mRNA/cDNA sequence sites?
Date: 7 Jun 1995 22:46:15 GMT
Organization: Biology, Indiana University - Bloomington
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Xref: biosci bionet.general:15655 sci.bio:17108 bionet.software:12310

IUBio Archive provides keyword searches of Genbank, PIR and SwissProtein 
databases.  OWL is a non-redundant amalgam of these.  Though I can't 
offer you OWL searching, I can offer you output of your searches in a 
variety of formats, including:
 
 biosequence/genbank
 biosequence/fasta
 biosequence/gcg
 biosequence/embl
 biosequence/msf
 biosequence/nbrf
 biosequence/phylip
 biosequence/paup
 biosequence/pir
 text/plain

The caveat to this is that this server uses 'readseq' to convert
to new formats, and this converter drops out the documentation
from sequence entries.  Your need might be served by choosing 
the biosequence/fasta format, which has no spaces, but has 50 bases 
per line.  If you want all the documentation, choose the default
or text/plain format.

You can find this data server thru www clients, at
  http://iubio.bio.indiana.edu/, look in folder Genbank-Sequences/
or by gopher+ to iubio.bio.indiana.edu, in folder Genbank-Sequences/

P.S., you might also like to try the sequence retrieval service (SRS)
at this site:  Pick "SRS @ IUBio" from the main IUBio menu.

In article <3r4ous$76d@vixen.cso.uiuc.edu> don@meibm25.cen.uiuc.edu (Don A. Walthers) writes:
>i'm trying to find a site that stores sequences without any spaces between
>a certain number of nucleotides. when i search the owl database at 
>www.gbd.org and pick the appropriate match any sequences available have
>spaces inserted every 10 NT for easier reading. i'd like to use a text 
>editor to search for restriction sites and other various sequences
>but the spaces would interfere. thanks for any info
-- 
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-software@net.bio.net Wed Jun 07 23:00:00 1995
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From: none (Meagan Moore)
Newsgroups: bionet.software
Subject: Re: Anatomy graphics
Date: 7 Jun 1995 23:19:50 GMT
Organization: MSU
Lines: 34
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In article <3r51gu$fmp@acme.freenet.columbus.oh.us>, 
hcampbel@freenet.columbus.oh.us says...
>
>   I have downloaded wha