From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
Path: biosci!daresbury!bioftp.unibas.ch!news.vub.ac.be!ben!gbottu
From: gbottu@ben.vub.ac.be (Guy Bottu)
Newsgroups: bionet.software
Subject: T cell epitope prediction ?
Date: 2 Apr 1997 07:58:34 GMT
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Does someone know of a software to predict T cell epitopes or
maybe a public Server where a protein can be submitted to such
a program ?

	Dr. Guy Bottu

From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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FULL VERSION  

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From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: "Nike" <nike@college.edu>
Newsgroups: bionet.software
Subject: Amplify?
Date: 1 Apr 1997 05:41:51 GMT
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Can anyone direct me where to find the program "Amplify"?

Thanks,

Thom Knowles
Princeton University
nike@cs.princeton.edu

From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: menendez@sun2.ruf.uni-freiburg.de (Castor Menendez)
Newsgroups: bionet.software
Subject: Looking for software
Date: 2 Apr 1997 09:41:57 GMT
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Dear Netters,

I would like to improve my typewritting.
Does anyone knows of a PC-IBM compatible software
to train these skills. A freeware or shareware would
be welcomed.

Thanks,  CM

--
Castor Menendez <menendez@sun1.ruf.uni-freiburg.de>

From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: C Coward <cc122@mole.bio.cam.ac.uk.trim.the.last.five.items>
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Manipulating ABI Chromatogram files
Date: 2 Apr 1997 14:04:09 GMT
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Xref: biosci bionet.molbio.methds-reagnts:56286 bionet.software:18259

Greetings to the world.....

I have numerous chromatogram sequence files generated from an ABI
automatic sequencing machine. I want to be able to make figures using
parts of the chromatograms to point out features alongside the
chromatogram traces. Does anyone know a way of doing this? I have access
to the ABI Macintosh programs on the machine used for sequencing and the
Sequencher v3.0 sequence analysis program from GeneCodes.

Cheers in advance.

Chris

------------------------------------------------------------------------------
Chris Coward                           | Tel: +44 1223 333545
University of Cambridge                | Fax: +44 1223 333346
Department of Pathology                | E-mail: cc122@mole.bio.cam.ac.uk
Tennis Court Road, Cambridge.          |        (MIME compliant)
CB2 1QP                                |
------------------------------------------------------------------------------
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From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: C Coward <cc122@mole.bio.cam.ac.uk.trim.the.last.five.items>
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: 2 Apr 1997 16:14:24 GMT
Organization: University of Cambridge, England
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"Dr. Duncan Clark" <duncan@genesys.demon.co.uk> writes:

>Try Chromas on a PC

>http://trishul.sci.gu.edu.au/~conor/chromas.html

>I use it to capture any part of the chromatogram using LviewPro to then
>manipulate the graphic size and format etc 

Cheers - unfortunately I don't have access to a PC.......

------------------------------------------------------------------------------
Chris Coward                           | Tel: +44 1223 333545
University of Cambridge                | Fax: +44 1223 333346
Department of Pathology                | E-mail: cc122@mole.bio.cam.ac.uk
Tennis Court Road, Cambridge.          |        (MIME compliant)
CB2 1QP                                |
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------------------------------------------------------------------------------


From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: Ketchup@cris.com (ketchup)
Newsgroups: bionet.software
Subject: Re: protein sequence analysis
Date: Wed, 02 Apr 1997 19:12:02 GMT
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If you can run a PC/Windows program, GeneDoc may be of some help.
While it will not automatically align sequences for you, it will shade
sequences with secondary structure information and allow you to
manually align the shaded sequences. Perhaps the initial alignment can
be made with the 'usual' program and then tuned for structure
considerations with GeneDoc.

Also, Structural Alignments done by the Argos Goup with the 3d_ali
effort can be downloaded viewed from the GeneDoc home page.

Hope this helps.

http://www.cris.com/~ketchup/genedoc.shtml

Karl Nicholas.


tnorris@molbio.uoregon.edu (Tracy B Norris) wrote:

>I am looking for a software program that will allow me to do specialized
>alignments of protein sequence. I would like to align structural elements
>of one sequence with another protein sequence. I have tried alignments in
>MegAlign, but as a consequence of alignment the program puts gaps in the
>structural elements of the first sequence (it's shorter than the other). 

>Any ideas?

>Thanks,

>Tracy



From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: "Dr. Duncan Clark" <duncan@genesys.demon.co.uk>
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: Wed, 2 Apr 1997 16:34:27 +0100
Organization: GeneSys Ltd
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In article <5htp0p$9f6@lyra.csx.cam.ac.uk>, C Coward <cc122@mole.bio.cam
.ac.uk.trim.the.last.five.items> writes
>Greetings to the world.....
>
>I have numerous chromatogram sequence files generated from an ABI
>automatic sequencing machine. I want to be able to make figures using
>parts of the chromatograms to point out features alongside the
>chromatogram traces. Does anyone know a way of doing this? I have access
>to the ABI Macintosh programs on the machine used for sequencing and the
>Sequencher v3.0 sequence analysis program from GeneCodes.
>

Try Chromas on a PC

http://trishul.sci.gu.edu.au/~conor/chromas.html

I use it to capture any part of the chromatogram using LviewPro to then
manipulate the graphic size and format etc 

Duncan
-- 
The problem with being on the cutting edge is that you occasionally get 
sliced from time to time....

Duncan Clark
DNAmp Ltd.
TEl/FAX 01252376288
http://www.dnamp.com
http://www.genesys.demon.co.uk

From owner-software@net.bio.net Tue Apr 01 23:00:00 1997
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From: tnorris@molbio.uoregon.edu (Tracy B Norris)
Newsgroups: bionet.software
Subject: protein sequence analysis
Date: 2 Apr 1997 04:42:35 GMT
Organization: University of Oregon
Lines: 11
Message-ID: <tnorris-0104971943490001@fp1-chemistry-4.uoregon.edu>
NNTP-Posting-Host: fp1-chemistry-4.uoregon.edu

I am looking for a software program that will allow me to do specialized
alignments of protein sequence. I would like to align structural elements
of one sequence with another protein sequence. I have tried alignments in
MegAlign, but as a consequence of alignment the program puts gaps in the
structural elements of the first sequence (it's shorter than the other). 

Any ideas?

Thanks,

Tracy

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: jquinn@best.com (Greg)
Newsgroups: bionet.software
Subject: Re: C++ on unix
Date: 3 Apr 1997 20:30:43 GMT
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You'll need to include code, Joe, for anyone to be able to help.

Joe Oppon (joe@techno.sanbi.ac.za) wrote:
: Hi everyone,

:  I have a problem with compiling my C++ program on SGI that 

:  I am using. A test program which runs oerfectly well on

:  an IDE enviroment comes up with a lot of "mistakes" on the unix

:   system running on SGI.



:  Is there something that I am not doing right ?




: Desperado !!

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: "Douglas Ward" <sciedsoft@msn.com>
Newsgroups: bionet.software
Subject: Re: Clone Manager?
Date: 3 Apr 1997 21:00:50 GMT
Organization: Sci-Ed Software
Lines: 31
Message-ID: <01bc4070$4512dc30$01010101@douglas>
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caw@SPAM@bcc.louisville.edu wrote in article
<5hrep0$pjl$1@hermes-x.louisville.edu>...
> Does anybody know if there is a version of Clone Manager beyond version
4.0?
> and if so where I can get it?  I can't find Scientific and Educational
Software(the 
> company) to save my life.
> 

Scientific and Educational Software moved to Durham, NC last year. 
Registered
users of our software were notified.  We are sorry that your notice must
have
been lost in the mail.  You can contact us at:

Mail:   PO Box 72045, Durham, NC 27722-2045, USA
Phone:  (919)-471-6064
FAX:     (919)-471-0311
URL:	www.scied.com
Email	sciedsoft@msn.com

The current version of Clone Manager is 4.1 and provides full compatibility
and molecule sharing with our Primer Designer V3 software. It is also
compatible with our Align Plus V3 program which will be released next week.

Sincerely
Douglas Ward, Ph.D.
Scientific and Educational Software


From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: trichmon@students.wisc.edu (Todd Richmond)
Newsgroups: bionet.software
Subject: Re: Amplify?
Date: Thu, 03 Apr 97 16:11:02 GMT
Organization: UW-Madison Dept of Botany
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In article <01bc3e5f$60ca09c0$0387b48c@swoosh.student.Princeton.EDU>, "Nike" <nike@college.edu> wrote:
>Can anyone direct me where to find the program "Amplify"?

Try the Amplify page at:

http://www.wisc.edu/genetics/CATG/amplify/index.html

Todd

*********************************************************
Todd Richmond                   UW-Madison Dept of Botany
B129 Birge Hall                 trichmon@students.wisc.edu
430 Lincoln Drive               Phone: 608-262-4008
Madison, WI 53706               Fax: 608-262-7509

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: krasel@wpxx02.toxi.uni-wuerzburg.de (Cornelius Krasel)
Newsgroups: bionet.software
Subject: Re: ReadSeq Bug
Date: Thu, 3 Apr 1997 17:33:49 +0200
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Michael Yasayko (yasayko@darwin.com) wrote:
> I've discovered a potentially fatal bug in the Feb 1 1993 release of
> "ReadSeq".  ReadSeq, authored by Don Gilbert of Indiana University,
> conveniently converts between most of the major sequence file types that
> people have developed over the years.  ReadSeq is available at:
> 
>   ftp://ftp.bio.indiana.edu/molbio/readseq/

I found a file in my distribution of readseq which contains this patch
and a couple of others. I have no idea who did these patches apart from
where noted. The patches have the following effects on my Linux machine:

a) Better recognition of PIR files as obtained from the server at the
   NCBI.
b) Correct calculation of 32-bit checksum (this seems a really serious
   bug to me; maybe on other platforms compilers behave differently?).
c) No warnings during compilation.
d) No more problems with sequence lines which don't end with line feeds
   (first published by jip@helix.nih.gov (John Powell)).

To apply the patches (which are in a so-called "unified diff" format),
do the following (on Unix machines):

1) Extract the following file (between the ---snip--- signs) into
   a separate text file. Let's call it patch-PL3 (that's what it is
   called on my harddisk :-). Put this file in the same directory
   where your readseq sources are located.
2) Change to the directory where your readseq sources are located
   and do a
        patch < patch-PL3
   This will modify your source files and generate a couple of files
   called blabla.c.orig. These contain your original source code.
3) Compile readseq as usual.

---snip---
--- readseq.c.orig	Thu Jan  5 00:28:51 1995
+++ readseq.c	Thu Jan  5 00:29:02 1995
@@ -180,7 +180,7 @@
 
 static char inputfilestore[256], *inputfile = inputfilestore;
 
-const char *formats[kMaxFormat+1] = {
+char *formats[kMaxFormat+1] = {
     " 1. IG/Stanford",
     " 2. GenBank/GB",
     " 3. NBRF",
--- ureadseq.c.orig	Thu Dec 22 19:28:59 1994
+++ ureadseq.c	Sat Jan  7 14:00:54 1995
@@ -297,7 +297,12 @@
 { /*PIR -- many seqs/file */
 
   while (!V->allDone) {
+    /* Skip header */
+    /* ENTRY or SEQUENCE has to be the first word in a line
     while (! (feof(V->f) || strstr(V->s,"ENTRY")  || strstr(V->s,"SEQUENCE")) )
+    */
+    /* ENTRY or SEQUENCE has to be the only word in a line */
+    while (! (feof(V->f) || !strcmp(V->s,"ENTRY")  || !strcmp(V->s,"SEQUENCE")) )
       getline(V);
     strcpy(V->seqid, (V->s)+16);
     while (! (feof(V->f) || strstr(V->s,"SEQUENCE") == V->s))
@@ -1477,7 +1482,9 @@
   register unsigned long c = 0xffffffffL;
   register long n = seqlen;
 
-  while (n--) c = crctab[((int)c ^ (to_upper(*seq++))) & 0xff] ^ (c >> 8);
+  while (n--) {
+      c = crctab[((int)c ^ (to_upper(*seq))) & 0xff] ^ (c >> 8); *seq++;
+  }
   c= c ^ 0xffffffffL;
   *checktotal += c;
   return c;
@@ -1634,7 +1641,8 @@
       fprintf(outf,"ENTRY           %s \n", idword);
       fprintf(outf,"TITLE           %s, %d bases, %X checksum.\n", seqname, seqlen, checksum);
    /* fprintf(outf,"ACCESSION       %s\n", accnum); */
-      fprintf(outf,"SEQUENCE        \n");
+   /* fprintf(outf,"SEQUENCE        \n"); */
+      fprintf(outf,"SEQUENCE\n");
       numwidth = 7;
       width= 30;
       spacer = kSpaceAll;
--- ureadseq.c.orig	Fri Nov 24 18:01:24 1995
+++ ureadseq.c	Fri Nov 24 18:01:09 1995
@@ -133,6 +133,11 @@
   else {
     cp = strchr(s, '\n');
     if (cp != NULL) *cp = 0;
+    /*
+     *  Following line fixes BUG when last line in the input does not have
+     *  an EOL character
+     */
+    if (feof(f)) clearerr(f);
     }
 }
 
--- readseq.c.orig	Fri Nov 24 17:46:34 1995
+++ readseq.c	Fri Nov 24 17:47:09 1995
@@ -19,7 +19,7 @@
  */
 
 const char *title
-    = "readSeq (1Feb93), multi-format molbio sequence reader.\n";
+    = "readSeq (1Feb93) PL3 (24Nov95), multi-format molbio sequence reader.\n";
 
  /*  History
   27 Feb 90.  1st release to public.
---snip---

If you don't have "patch", unified diffs are fairly easy to comprehend.
Look at the first character in a line. If you find a minus sign, it means
that this line has to be "subtracted" from your original source code.
If you find a plus sign, you have to "add" the line to your source code.

--Cornelius.

-- 
/* Cornelius Krasel, U Wuerzburg, Dept. of Pharmacology, Versbacher Str. 9 */
/* D-97078 Wuerzburg, Germany   email: phak004@rzbox.uni-wuerzburg.de  SP3 */
/* "Science is the game we play with God to find out what His rules are."  */

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: Joe Oppon <joe@techno.sanbi.ac.za>
Newsgroups: bionet.software
Subject: Compiler for C++
Date: Thu, 03 Apr 1997 13:37:11 +0200
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Hi everyone,

 I have a problem with compiling my C++ program on SGI that 

 I am using. A test program which runs oerfectly well on

 an IDE enviroment comes up with a lot of "mistakes" on the unix

  system running on SGI.



 Is there something that I am not doing right ?


 Desperado !!

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
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From: Joe Oppon <joe@techno.sanbi.ac.za>
Newsgroups: bionet.software
Subject: C++ on unix
Date: Thu, 03 Apr 1997 13:16:30 +0200
Organization: sanbi
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Hi everyone,

 I have a problem with compiling my C++ program on SGI that 

 I am using. A test program which runs oerfectly well on

 an IDE enviroment comes up with a lot of "mistakes" on the unix

  system running on SGI.



 Is there something that I am not doing right ?




Desperado !!

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!mindspring!cpk-news-hub1.bbnplanet.com!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!howland.erols.net!cs.utexas.edu!news.eng.convex.com!news.ecn.uoknor.edu!munnari.OZ.AU!harbinger.cc.monash.edu.au!news.uwa.edu.au!not-for-mail
From: Steve Woods <swoods@cyllene.uwa.edu.au>
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: Thu, 03 Apr 1997 11:26:04 +0800
Organization: Biochem UWA
Lines: 14
Message-ID: <3343234C.49CE@cyllene.uwa.edu.au>
References: <5htp0p$9f6@lyra.csx.cam.ac.uk> <PH7bQGADynQzEwEa@genesys.demon.co.uk> <5hu0l0$dse@lyra.csx.cam.ac.uk>
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To: C Coward <cc122@mole.bio.cam.ac.uk.trim.the.last.five.items>
Xref: biosci bionet.molbio.methds-reagnts:56314 bionet.software:18265

There is a similar program for the Mac.

Try looking for SeqED (I forget where from - email me if you need me to
find it).

It does multiple alignments and can display all or part of the original
chromatograms.

Hope this helps.
-- 
  ,-_|\    Steve Woods      email: swoods@cyllene.uwa.edu.au  
 /     \   PhD Student      phone: 380 1394    fax: 380 1148
 *_,-._/   Department of Biochemistry, UWA
      v    http://www.general.uwa.edu.au/u/swoods/

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!agate!howland.erols.net!cam-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ais.net!ameritech.net!uunet!in3.uu.net!204.238.120.21!jump.net!grunt.dejanews.com!not-for-mail
Date: Wed, 02 Apr 1997 19:21:43 -0600
From: yasayko@darwin.com (Michael Yasayko)
Subject: ReadSeq Bug
Newsgroups: bionet.software
Message-ID: <860029387.2018@dejanews.com>
Reply-To: yasayko@darwin.com
Organization: Darwin Molecular Corporation
To: yasayko@darwin.com
X-Article-Creation-Date: Thu Apr 03 01:03:07 1997 GMT
X-Originating-IP-Addr: 199.238.223.1 (gateway.darwin.com)
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I've discovered a potentially fatal bug in the Feb 1 1993 release of
"ReadSeq".  ReadSeq, authored by Don Gilbert of Indiana University,
conveniently converts between most of the major sequence file types that
people have developed over the years.  ReadSeq is available at:

  ftp://ftp.bio.indiana.edu/molbio/readseq/

On modern machines, the bug typically shows up only in large sequence
files.	Nonetheless, the bug can theoretically affect files of any
length.  The most common manifestation of the bug on our Solaris 2.4
machines is a "segmentation fault".

The bug is in "ureadseq.c" line 1480.  The following changes will fix it;
the diff command line was:

  diff "original" "fixed"

In other words, the code lines following the "<"s needs to be replaced
with the code lines following the ">"s:

] diff ureadseq.c ../../readseqd/ureadseq.c
1480c1480,1483
<   while (n--) c = crctab[((int)c ^ (to_upper(*seq++))) & 0xff] ^ (c >>
8);
---
>   while (n--) {
>      c = crctab[((int)c ^ (to_upper(*seq))) & 0xff] ^ (c >> 8);
>      seq++;
>   }

Technical notes on why this is a bug:

"to_upper" is a preprocessor macro, not a function.  The macro makes use
of the argument parameter twice within the macro body:

  #define to_upper(c) ((char)(is_lower(c) ? (c)-' ' : (c)))

Hence, placing a variable along with the increment operator (*seq++) into
the macro arg list yields code which increments "seq" twice per iteration
of the "while" loop, not just once as intended.  Hence, the code skips
over every second character in the sequence, eventually running past the
end of the allocated memory for "char *seq".

My guess is that the bug is also making the "checksum" results invalid,
although I could be mistaken as I don't know how this particular
"checksum" really works.

--Mike

__________________________________________________________________________
Mike Yasayko, Scientific Programmer, Darwin Molecular Corporation
E-mail:  yasayko@darwin.com

-------------------==== Posted via Deja News ====-----------------------
      http://www.dejanews.com/     Search, Read, Post to Usenet

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!daresbury!is.bbsrc.ac.uk!news
From: Pat Thoyts <thoyts@bsa.bristol.ac.uk>
Newsgroups: bionet.software
Subject: Re: Compiler for C++
Date: Thu, 03 Apr 1997 21:20:51 +0100
Organization: IACR-Long Ashton Research Station
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Joe Oppon wrote:
 > 
 > Hi everyone,
 > 
 >  I have a problem with compiling my C++ program on SGI that
 >  I am using. A test program which runs oerfectly well on
 >  an IDE enviroment comes up with a lot of "mistakes" on the unix
 >  system running on SGI.
 >  Is there something that I am not doing right ?
 > 
 >  Desperado !!

Without knowing what messages were produced I couldn't even guess!

-- 
Pat Thoyts                           mailto:thoyts@bsa.bristol.ac.uk
                      http://pc0652.lars.bbsrc.ac.uk/~pat/home.shtml

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!daresbury!is.bbsrc.ac.uk!news
From: Pat Thoyts <thoyts@bsa.bristol.ac.uk>
Newsgroups: bionet.software
Subject: Re: ReadSeq Bug
Date: Thu, 03 Apr 1997 21:19:32 +0100
Organization: IACR-Long Ashton Research Station
Lines: 14
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References: <860029387.2018@dejanews.com>
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To: yasayko@darwin.com

I think readseq got itself wrapped up in the seqio library. The new
version comes under the name fmtseq but does the same job. The version
that I have is seqio-1.2.2 and mentions in the README

 This software uses the SEQIO package for reading and writing
 sequences. Copyright (c) 1996 by James Knight at Univ. of
 California, Davis. 

So it's a bit more recent than readseq. I don't know if the bug you
mention is in there though.

-- 
Pat Thoyts                           mailto:thoyts@bsa.bristol.ac.uk
                      http://pc0652.lars.bbsrc.ac.uk/~pat/home.shtml

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!MAIL.UTEXAS.EDU!kbrowning
From: kbrowning@MAIL.UTEXAS.EDU (Karen Browning)
Newsgroups: bionet.software
Subject: Windows DNA/Protein analysis programs
Date: 3 Apr 1997 11:28:24 -0800
Organization: University of Texas at Austin
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Here we go again.  GeneRunner is apparently out of business.  Does
anyone know of a user friendly, inexpensive DNA/protein analysis program
for Windows that does what GeneRunner did.  I would also like to be able
to do contigs for DNA sequencing, etc.

Can anyone explain to me why this is so difficult?

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Path: biosci!daresbury!uninett.no!hermod.uio.no!nntp.uio.no!newsfeeds.sol.net!news-xfer.netaxs.com!cpk-news-hub1.bbnplanet.com!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!hermes.sovam.com!sovam!demos!news.stealth.net!news.ibm.net.il!news.ibm.net!news.biu.ac.il!news.huji.ac.il!wisipc.weizmann.ac.il!gustavo-pm8200.weizmann.ac.il!bmgustav
From: Gustavo Glusman <bmgustav@bioinfo.weizmann.ac.il>
Subject: Re: Manipulating ABI Chromatogram files
Content-Type: text/plain; charset=ISO-8859-1
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Xref: biosci bionet.molbio.methds-reagnts:56343 bionet.software:18272

In article <5htp0p$9f6@lyra.csx.cam.ac.uk> C Coward,
cc122@mole.bio.cam.ac.uk.trim.the.last.five.items writes:
>I have numerous chromatogram sequence files generated from an ABI
>automatic sequencing machine. I want to be able to make figures using
>parts of the chromatograms to point out features alongside the
>chromatogram traces. Does anyone know a way of doing this? I have access
>to the ABI Macintosh programs on the machine used for sequencing and the
>Sequencher v3.0 sequence analysis program from GeneCodes.

The simplest way:

- Display the chromatogram using Sequencher
- Capture the screen (command-shift-3, or use some utility like Flash-It for
capturing only part of the screen)
- If you captured the whole screen, double-click on the resulting picture file
on your hard-drive, it will open with SimpleText. Select what you need from
it, and copy.
- Paste into Canvas or some other graphical program.
- Add other stuff to point out features, etc.

Is this what you needed?

     ____________________________________________________________
     Gustavo Glusman              Founder/administrator of BioMOO
     Gustavo@bioinfo.weizmann.ac.il    (public PGP key available)
     http://bioinfo.weizmann.ac.il/Gustavo
        Visit BioMOO, the biologists' virtual meeting place, at
     ___________ http://bioinfo.weizmann.ac.il/BioMOO ___________

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!news.icm.edu.pl!newsfeed.nacamar.de!azure.xara.net!xara.net!rill.news.pipex.net!pipex!uunet!in1.uu.net!199.232.56.18!news.ultranet.com!not-for-mail
From: "carlg" <carlg@ultranet.com>
Newsgroups: bionet.software
Subject: peak detection macro for Excel
Date: 3 Apr 1997 21:03:54 GMT
Organization: Avitar Technologies
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NNTP-Posting-Host: d16.dial-1.met.ma.ultra.net
X-Newsreader: Microsoft Internet News 4.70.1161

Hi,
I need a peak detection macro for Excel.  It should work on a column of
numbers
to identify peaks and provide a peak height or area.  Does anyone know of
one.

Thanks for your help

-- 
Dr. Carl M. Good III, Ph.D.
Vice President Research and Development
Avitar Inc.
65 Dan Road
Canton, MA 02021, USA
Phone (617) 821-2440, FAX (617) 821-4458
Email = carlg@ultranet.com
Web Page = http://www.ultranet.com/~carlg


From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!cyclic.gsl.net!news.gsl.net!newsfeed.nacamar.de!worldnet.att.net!newsadm
From: "Douglas Ward" <sciedsoft@msn.com>
Newsgroups: bionet.software
Subject: Re: Clone Manager?
Date: 3 Apr 1997 21:00:52 GMT
Organization: Sci-Ed Software
Lines: 32
Message-ID: <01bc4071$c88df580$01010101@douglas>
References: <5hrep0$pjl$1@hermes-x.louisville.edu>
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caw@SPAM@bcc.louisville.edu wrote in article
<5hrep0$pjl$1@hermes-x.louisville.edu>...

> Does anybody know if there is a version of Clone Manager beyond version
4.0?
> and if so where I can get it?  I can't find Scientific and Educational
Software(the 
> company) to save my life.


Scientific and Educational Software moved to Durham, NC last year. 
Registered
users of our software were notified.  We are sorry that your notice must
have been
lost in the mail.  You can contact us at:

Mail:	PO Box 72045, Durham NC 27722-2045, USA
Phone:	(919) 471-6064
FAX:	(919) 471-0311
Email:	sciedsoft@msn.com
URL:	www.scied.com

The current version of Clone Manager for Windows is 4.1 and enables full
compatibility and molecule sharing with our Primer Designer V3 software.  
It is also compatible with our Align Plus V3 program to be released next
week.

Sincerely
Douglas Ward, Ph.D.
Scientific and Educational Software


From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!agate!howland.erols.net!news.nacamar.de!newsfeed.nacamar.de!news-kar1.dfn.de!news-fra1.dfn.de!news-ge.switch.ch!feed1.belnet.be!news.belnet.be!news.vub.ac.be!usenet
From: Erik Jongert <ejongert@.vub.ac.be>
Newsgroups: alt.mac.games.binaries,alt.hackintosh,bionet.software
Subject: Please Post MacPlasmap v2.1
Date: Thu, 03 Apr 1997 15:33:35 +0100
Organization: VUB
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Hi,

I'm looking for a NON DEMO version of MacPlasmap v2.1 or higher.

Please Post it

Erik

From owner-software@net.bio.net Wed Apr 02 23:00:00 1997
Path: biosci!MAIL.TSINGHUA.EDU.CN!congjy
From: congjy@MAIL.TSINGHUA.EDU.CN (Jinyang Cong)
Newsgroups: bionet.software
Subject: software for predicting antigenesity
Date: 3 Apr 1997 14:49:01 -0800
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Hi, I would appreciate very much if someone can tell me where I can get a 
software to analyze a amino acid sequence of any protein to predict its 
antigenic epitopes. I am working at using synthetic peptides as antigens to 
make monoclonal antibodies. This kind of software is very useful for me. Any 
information would be welcome.
    Cong, JY 


From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
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From: tday@netcom.com (Tony Day)
Newsgroups: bionet.software
Subject: Expert in Bioinformatics? - Earn Extra Cash!!
Date: Thu, 03 Apr 1997 18:25:30 -0700
Organization: Netcom
Lines: 14
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Sorry if this is a repost, I have been having server trouble.

We are a biotech company in the San Francisco Bay area looking for someone
to spend a few days helping us to do some sequence searches, and alignments
using GCG and using internet resources.  If you have EXPERT knowledge of
GCG and internet databases and would like to earn some extra money for a
few days work, please email me at:

TDAY@GENENCOR.COM

or call me at 415-846-5822.


Tony Day

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!worldnet.att.net!news.maxwell.syr.edu!news.apfel.de!news-fra1.dfn.de!news-ge.switch.ch!feed1.belnet.be!news.belnet.be!news.vub.ac.be!usenet
From: plebrun@fysp1.vub.ac.be (Philippe Lebrun)
Newsgroups: bionet.software
Subject: statistics and pharmacology
Date: 4 Apr 1997 11:21:46 GMT
Organization: Brussels Free Universities VUB/ULB
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Does anyone know of software that will calculate regerssion parameters and
ED50 value of dose-response curves? 

Currently I'm doing it by hand (by hand in Excel, that is) but I'm not sure 
at all of my results.

Thanks,
Philippe

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
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From: cunninghamc@marlab.ac.uk
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: Thu, 03 Apr 1997 10:00:40 +0100
Organization: University of Aberdeen,  Scotland
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Xref: biosci bionet.molbio.methds-reagnts:56365 bionet.software:18283

In article <5htp0p$9f6@lyra.csx.cam.ac.uk>, C Coward
<cc122@mole.bio.cam.ac.uk.trim.the.last.five.items> wrote:

> Greetings to the world.....
> 
> I have numerous chromatogram sequence files generated from an ABI
> automatic sequencing machine. I want to be able to make figures using
> parts of the chromatograms to point out features alongside the
> chromatogram traces. Does anyone know a way of doing this? I have access
> to the ABI Macintosh programs on the machine used for sequencing and the
> Sequencher v3.0 sequence analysis program from GeneCodes.
> 
> Cheers in advance.
> 
> Chris
> 
Chris, 
I haven't used Sequencher yet, so I'm not sure if it's capable of this
sort of thing.  Previously, I've had to resort to filling the screen with
the required segment of chromatogram (in the relevant ABI application),
then taking a 'snapshot' of the screen (command - shift - 3) to creat a
PICT file on the hard disk which can then be imported and labelled etc. in
a graphics package.  It's a bit basic but did the job.  I'll be interested
in any more sophisticated ways of doing this.
Good luck
Carey

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!HERCULES.SDSC.EDU!bourne
From: bourne@HERCULES.SDSC.EDU (Philip Bourne)
Newsgroups: bionet.software
Subject: Proceedings of Crystallographic Computing 7
Date: 4 Apr 1997 13:23:34 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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Message-ID: <Pine.SGI.3.95.970404130930.6191B-100000@hercules.sdsc.edu>
Reply-To: Philip Bourne <bourne@hercules.sdsc.edu>
NNTP-Posting-Host: net.bio.net


The electronic version of the Proceedings of Crystallographic Computing 7
are now available at http://www.sdsc.edu/Xtal/IUCr/CC/School96/ or via
anonymous ftp from ftp.sdsc.edu in the directory
pub/sdsc/societies/IUCr/School96/

This meeting was sponsored by the Computing Commission of the
International Union of Crystallography (IUCr) and covered all aspects of
macromolecular crystallographic computing. A list of the papers is
appended.

Philip E. Bourne
Chairman, IUCr Computing Commission.

----------------------------------------------------------------------------
 
Editorial Phil Bourne and Keith Watenpaugh 
Acknowledgments 
Introduction Jim Stewart and Phil Bourne 

Contents 

Macromolecular Crystallographic Data

Quality and Quantity

The Protein Data Bank: Current Status and Future Challenges Joel Sussman,
Enrique Abola, Nancy Manning and Jaime Prilusky 

Methods to Assess and Classify Protein Structure Coordinates Janet Thornton,
A. Michie, E. Hutchinson, R. Laskowski, and C. Orengo

Procedures for Assessing the Quality of X-ray Structures of Macromolecules
Shoshana Wodak, Joan Pontius, Alexei Vaguine, and Jean Richelle 

Databases

Development of Crystallization Strategies using the Biological Macromolecule
Crystallization Database Gary Gilliland, Michael Tung and Jane Ladner

The Network Interface to the Nucleic Acid Database Helen Berman, Lester
Clowney, Anke Gelbin, Christine Zardecki and John Westbrook 

Structure Comparison

Structural Neighbors and Structural Alignments: The Science behind Entrez/3D
Steve Bryant and Christopher Hogue 

Real-Time Substructure Searching using the Conformational Likeness Method
Misha Ponomarenko, Ilya Shindyalov and Phil Bourne 

Methodology

Data Processing

Data Processing in Macromolecular Crystallography Andrew Howard 

Advances in Accuracy and Automation of Data Collection and Processing Wladek
Minor and Zbyszek Otwinowski 

Data Acquisition and Analysis at the Structural Biology Center Mary
Westbrook and Jim Pflugrath 

Phasing

Plenary Lecture The Phase Problem: a Problem in Constrained Global
Optimization Herb Hauptman 

Maximum-Likelihood Refinement of Incomplete Models with BUSTER and TNT John
Irwin and Gerard Bricogne 

Optimization of Electron Density Cross-Correlation with Its Square:
Relationships for Phase Extension and Refinement Douglas Collins, John
Konnert and James Stewart 

Integration of Direct Method with Macromolecular Crystallographic Techniques
Carmelo Giacovazzo, D. Siliqi and J. Gonzalez-Platas 

SnB: Applying Shake-and-Bake to Proteins 

A Rotation Function that uses Phases Richard Leggott and Peter Main

Refinement

High-resolution Structure Refinement George Sheldrick 

Full Matrix Least Squares Lynn Ten Eyck 

Electron Density Representation and Real Space Refinement E. Blanc, G. Zhou,
Z. Chen, Q. Zie, J. Tang, J. Wang and Michael Chapman 

The Joint Refinement of Inhibitors of Thermolysin Dale Tronrud 

Model Building

LORE: A Tool for Manipulating Known Structural Information in Protein
Modeling and Crystallography Barry Finzel 

A Semi-automated Map Fitting Procedure Thomas Oldfield 

Visualization

Considerations in the Design of Graphical User Interfaces for Macromolecular
Crystallography Robert Sweet and John Skinner 

Surface Lexicography Anthony Nicholls 

An AVS/Express Interface to CCP4 David Wild and S. Choe 

Student Presentation: Sysabs - A program for the Visualization of Crystal
Data Symmetry in Reciprocal Space. Craig Taverner 

Software Updates

XtalView Duncan McRee and Mark Israel 

The PROTEIN System: Real Space Techniques using Patterson and Fourier Maps
Wolfgang Steigemann 

A Collaborative Computational Project, Number 4 CCP-4: Providing Programs
for Protein Crystallography Eleanor Dodson 

SHELX for Macromolecules George Sheldrick 

MAIN Dusan Turk 

SHARP Eric de La Fortelle, John Irwin, and Gerard Bricogne 

New Approaches

Crystallographic Topology and its Applications Carroll Johnson and Michael
Burnett 

The Macromolecular CIF Dictionary Paula Fitzgerald, Helen Berman, Phil
Bourne, Brian McMahon, Keith Watenpaugh and John Westbrook 

mmCIF Software Tools Shu-Hsin Hsieh, Steven Schirripa and John Westbrook

Supporting Technologies

Internet for Crystallographers - Beginners and Advanced Howard Flack 

Object Oriented Programming in Crystallography David Moss and William Pitt

Modification of Crystallographic Codes for Parallel Architectures
M.Ramanadham 
----------------------------------------------------------------------------



From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!agate!spool.mu.edu!uwm.edu!news-peer.gsl.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ais.net!ameritech.net!uunet!in1.uu.net!152.163.170.17!newstf01.news.aol.com!audrey01.news.aol.com!not-for-mail
From: haroldb786@aol.com (HaroldB786)
Newsgroups: bionet.software
Subject: Re: Windows DNA/Protein analysis programs
Date: 4 Apr 1997 20:49:13 GMT
Organization: AOL http://www.aol.com
Lines: 8
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References: <334407FF.3D1E@mail.utexas.edu>
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X-Admin: news@aol.com

First try www.ebi.ac.uk-- lots of software...... GeneDoc can be useful for
aligned sequences. MACAW also.

Pardon my ignorance, "contigs for DNA sequencing?"

Hope this helps,

harold

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!EU.net!sun4nl!uva.nl!nol.amc.uva.nl!news
From: "Jan Filip Hellings (staff)" <J.F.hellings@amc.uva.nl>
Newsgroups: bionet.software
Subject: Re: ReadSeq Bug
Date: Fri, 04 Apr 1997 14:22:52 +0200
Organization: AMC/ADIV/CRS
Lines: 45
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Michael Yasayko wrote:
> 
> I've discovered a potentially fatal bug in the Feb 1 1993 release of
> "ReadSeq".  ReadSeq, authored by Don Gilbert of Indiana University,
> conveniently converts between most of the major sequence file types that
> people have developed over the years.  ReadSeq is available at:
> 
>   ftp://ftp.bio.indiana.edu/molbio/readseq/
With Readseq I couldn't read files of raw format with only one line
so I changed the code a little. I hope it won't affect any other
functionality.
---cut here for the patch file----------------
*** ureadseq.c.orig     Fri Apr  4 13:27:19 1997
--- ureadseq.c  Fri Apr  4 14:09:30 1997
*************** short seqFileFormatFp(
*** 1330,1336 ****
        else if (foundFitch) format= kFitch;
            /* no format chars: */
        else if (otherlines > 0) format= kUnknown;
!       else if (dnalines > 1) format= kPlain;
        else if (aminolines > 1) format= kPlain;
        else format= kUnknown;
  
--- 1330,1336 ----
        else if (foundFitch) format= kFitch;
            /* no format chars: */
        else if (otherlines > 0) format= kUnknown;
!       else if (dnalines >= 1) format= kPlain;
        else if (aminolines > 1) format= kPlain;
        else format= kUnknown;
  

----------cut--------------------------------------
save this file and run:
patch < patchfile
make all
  
Yours
-- 
***************************Jan Hellings*********************************
* Academic hospital of the            Phone: (+31) 20 5667371          *
* University of Amsterdam/AMC/G02-209 FAX  : (+31) 20 5664440	       *
* Meibergdreef 9                                                       *
* 1105 AZ Amsterdam/Holland       Email  : j.f.hellings@amc.uva.nl     *
************************************************************************

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!news-xfer.netaxs.com!news.maxwell.syr.edu!news.apfel.de!news-fra1.dfn.de!news-ge.switch.ch!feed1.belnet.be!news.belnet.be!alpha.luc.ac.be!pstn11.luc.ac.be!user
From: ghermans@luc.ac.be (Guy Hermans)
Newsgroups: bionet.software
Subject: Re: T cell epitope prediction ?
Date: Fri, 04 Apr 1997 13:21:56 +0100
Organization: Dr. L. Willems-Instituut
Lines: 33
Message-ID: <ghermans-0404971321560001@pstn11.luc.ac.be>
References: <5ht3ja$odd@rc1.vub.ac.be>
NNTP-Posting-Host: pstn11.luc.ac.be

In article <5ht3ja$odd@rc1.vub.ac.be>, gbottu@ben.vub.ac.be (Guy Bottu) wrote:

> Does someone know of a software to predict T cell epitopes or
> maybe a public Server where a protein can be submitted to such
> a program ?
> 
>         Dr. Guy Bottu
Sure!

A number of methods has been proposed and evaluated. One Mac program,
called T-sites, incorporates a number of such methods.

It is freeware, and new versions could be obtained from the company where
the authors worked _at the time_. I tried to contact them for a new
version, but to no avail.

I'll include the program in a personal e-mail to you, so I won't have to
overload newsservers all over the planet. If someone out here wishes to
get a copy, please let me know personally.

Greetings to all

Guy

-- 
Guy Hermans, PhD student
  Ms research Unit              Immunology research group
  Dr. L. Willems-Institute      Dept. of Physiology, LUC
  University Campus             University Campus
  B-3590 Diepenbeek             B-3590 Diepenbeek
  Belgium                       Belgium
Voice  ++32(0)11/26.92.07
Fax    ++32(0)11/26.92.09

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!EU.net!news-peer.sprintlink.net!cs.utexas.edu!news.eng.convex.com!news.ecn.uoknor.edu!munnari.OZ.AU!news.mel.connect.com.au!news.mel.aone.net.au!usenet
From: "Phuc Hoang" <hoang@ans.com.au>
Newsgroups: bionet.software
Subject: Software for FREE
Date: 4 Apr 1997 06:21:11 GMT
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Only at : http://www.ans.com.au/~hoang/software

From owner-software@net.bio.net Thu Apr 03 23:00:00 1997
Path: biosci!agate!howland.erols.net!newsserver.jvnc.net!news.merck.com!internal.merck.com!user
From: mark_yeager@merck.com (Mark Yeager)
Newsgroups: bionet.molbio.methds-reagnts,bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: Thu, 03 Apr 1997 14:06:14 -0500
Organization: Merck & Co.
Lines: 25
Message-ID: <mark_yeager-0304971406140001@merck.com>
References: <5htp0p$9f6@lyra.csx.cam.ac.uk> <PH7bQGADynQzEwEa@genesys.demon.co.uk> <5hu0l0$dse@lyra.csx.cam.ac.uk> <3343234C.49CE@cyllene.uwa.edu.au>
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Xref: biosci bionet.molbio.methds-reagnts:56382 bionet.software:18289

In article <3343234C.49CE@cyllene.uwa.edu.au>, swoods@cyllene.uwa.edu.au wrote:

> There is a similar program for the Mac.
> 
> Try looking for SeqED (I forget where from - email me if you need me to
> find it).
> 
> It does multiple alignments and can display all or part of the original
> chromatograms.


The program EditView is free from Perkin Elmer/ABI

<ftp://192.43.251.1//pub/public/Sequencing/EditView/>

-- 
Mark Yeager    ->  mark_yeager@merck.com
   WP16-107, Dept. of Virus & Cell Biology
   Merck Research Labs, West Point, PA 19486


       The contents of this message express only the sender's opinion.
       This message does not necessarily reflect the policy or views of
       my employer, Merck & Co., Inc.  All responsibility for the statements
       made in this Usenet posting resides solely and completely with the
       sender.

From owner-software@net.bio.net Fri Apr 04 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news.maxwell.syr.edu!news.visi.net!mur2.odyssey.on.ca!news3.sprint-canada.net!roger.interlynx.net!not-for-mail
From: Lars Thomsen <lthomsen@interlynx.net>
Newsgroups: bionet.software
Subject: Curvefitting in Preader (free patch clamp analysis software) soon to come...
Date: Fri, 04 Apr 1997 19:45:01 -0800
Organization: Interlynx
Lines: 62
Message-ID: <3345CABD.7DCD@interlynx.net>
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Hi
Our freeware program Preader for analysis of  patch clamp data will soon
be include all the possible fitting routines that you can think of in
terms of pharmacological and electrophysiological analysis. We got a
very kind offer from GraphPad who will allow us to use the trial version
of their software in our program. This is really good because it takes a
lot of time to develop the curve fitting routines and now we can
concentrate on the more direct analysis. We also asked Jandel Software
(the maker of SigmaPlot) if there was a possibility to get a restricted
version of their software or something, but they said no.

Until recently I didn't know that GraphPad had such a good curve fitting
program as far as I can see it matches SigmaPlot pretty well and it
beats MicroCal Origin which I regret that I bought. So we are really
excited about this because we this will soon give us the analysis
program that we want. The reason why we make it is that we are PC users
and we do not want to jump to the Mac where AxoGraph is available. I
really like that program. We will make some things that you not will
find in AxoGraph which is a pretty smart database function utilizing SQL
language to sort/find the data. It means that one time you have entered
the information from your logbook (or used Preaders automatic features
for peaks and soon rise times, time constants etc.) then you can perform
the statistics that you want. This basically means that you do not have
to work yourself to dead by paging back and forth in your logbooks.
Recently I made 4 abstracts to the ISAN meeting in Cairns and it took me
the whole weekend to sort out the data from the logbook. If I had
finished that feature in Preader then I would have finished in one hour.
Example :

Find all concentrations of GABA=1000 µM give me the mean peak current,
50% rise time ± SD and ± SE.

Preader currently have a peak detector but version 1.7 (not released
yet) will improve this feature a lot. Preader also offers automatic
transfer to the database of the numbers returned from the analysis. I
think its smart...(but I also made it, so Im quite uncritical) Please
give some response if you think this is worth pursuing

We have just got VB5 and we will make the transition from VB4, which
should make the program faster.

We are also working very hard on getting the support for Cambridge
Electronic Designs file format CFS into our program. CED has also been
very helpful with the support for their file format.

You can go to the download page of Preader beta version 1.6 :
http://home.interlynx.net/~lthomsen/preader

You can mail me to obtain a password :
lthomsen@interlynx.net or thomsenl@fhs.mcmaster.ca

Please note that we haven't incorporated GraphPad Prism in our program
yet, but you can try the trial version by going to :
http://www.graphpad.com/www/welcome.html

--
Lars Thomsen, MSc Ph.D.
115 South Oval, Hamilton, L8S1R2 Ontario, Canada
tlp +1 905 777 0720 fax +1 905 777 0738
email lthomsen@interlynx.net
homepage http://home.interlynx.net/~lthomsen


From owner-software@net.bio.net Fri Apr 04 23:00:00 1997
Path: biosci!ACCEFYN.ORG!acad
From: acad@ACCEFYN.ORG (acad)
Newsgroups: bionet.software
Subject: help
Date: 5 Apr 1997 06:00:06 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 5
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Message-ID: <Pine.SGI.3.91.970405085840.17657A@apollo.request.net>
NNTP-Posting-Host: net.bio.net

How can I subscribe to this listserv, what other list does it handle? 

thanks



From owner-software@net.bio.net Fri Apr 04 23:00:00 1997
Path: biosci!agate!howland.erols.net!ix.netcom.com!super.zippo.com!zdc!news.onramp.net!news
From: jdean@scscomm.com (John D. Eanust)
Newsgroups: bionet.software
Subject: ANNOUNCE: Get Newsgroup Binaries Automatically
Date: Sat, 05 Apr 1997 04:09:25 GMT
Organization: OnRamp Technologies, Inc.; ISP
Lines: 12
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Reply-To: jdean@scscomm.com
NNTP-Posting-Host: ppp1-09.ftwotx.onramp.net
X-Newsreader: Forte Free Agent 1.0.82

The new software named "Pluckit" from www.pluckit.com intelligently
and automatically scans and downloads binary attachments from
newsgroups postings, based upon your interests.

Just select the groups of interest and press "start plucking" and then
while you watch, hundreds or thousands of binary attachments (fonts,
pictures, sound files, etc.) will flood into your hard drive.

Try the FREE evaluation copy of Pluckit from www.pluckit.com.




From owner-software@net.bio.net Sat Apr 05 23:00:00 1997
Path: biosci!MAIL.TSINGHUA.EDU.CN!congjy
From: congjy@MAIL.TSINGHUA.EDU.CN (Jinyang Cong)
Newsgroups: bionet.software
Subject: software for predicting antigenesity
Date: 6 Apr 1997 15:43:21 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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Message-ID: <9704062241.AB28999@mail>
NNTP-Posting-Host: net.bio.net

Hi, I would appreciate very much if someone can tell me where I can get a 
software to analyze a amino acid sequence of any protein to predict its 
antigenic epitopes. I am working at using synthetic peptides as antigens to 
make monoclonal antibodies. This kind of software is very useful for me. Any 
information would be welcome.
    Cong, JY 


From owner-software@net.bio.net Sat Apr 05 23:00:00 1997
Path: biosci!lmb.uni-muenchen!bmeister
From: bmeister@lmb.uni-muenchen (Ralf Baumeister)
Newsgroups: bionet.software
Subject: Sequence analysis software
Date: 6 Apr 1997 09:21:23 -0700
Organization: Genzentrum
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Dear all,

we are looking for a DNA sequence analysis program, similar to the MAC
program DNA Strider, which runs under Windows and is public domain or
not overly expensive.

Any suggestions?

Thanks

Ralf Baumeister

bmeister@lmb.uni-muenchen.de



From owner-software@net.bio.net Sat Apr 05 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!news-xfer.netaxs.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!newsfeed.nacamar.de!news1.best.com!nntp1.ba.best.com!nntp2.ba.best.com!shellx!jquinn
From: jquinn@best.com (Greg)
Newsgroups: bionet.software
Subject: Re: Windows DNA/Protein analysis programs
Date: 6 Apr 1997 02:14:29 GMT
Lines: 21
Distribution: world
Message-ID: <5i70u5$83q$1@nntp2.ba.best.com>
References: <334407FF.3D1E@mail.utexas.edu>
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X-Newsreader: TIN [version 1.2 PL2]

Karen Browning (kbrowning@MAIL.UTEXAS.EDU) wrote:
: Here we go again.  GeneRunner is apparently out of business.  Does
: anyone know of a user friendly, inexpensive DNA/protein analysis program
: for Windows that does what GeneRunner did.  I would also like to be able
: to do contigs for DNA sequencing, etc.
: Can anyone explain to me why this is so difficult?

It's not that difficult, given that windows has a massive backup in
terms of compilers, IDE's etc. However, it is time consuming to construct
a natty interface to the algorithms, and debug the stuff to a reasonable
degree, such that many people now try and sell their hard work rather than
distributing freely. If you check back in this group you'll see several
posts from people offering demo software of their sequence analysis
software. This whole thing may be circumvented soonish by the serious use
of Java, and since this is more or less platform independent (I say more
or less because I am one of many who are encountering platform problems
with Java) it would only take one kind soul to distribute a serious Java
app (not just a collection of relatively trivial applets) and it would run
on Windows, a Mac etc. etc. I am sure that will come from one serious
minded individual and/or research group in the near future.


From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!agate!howland.erols.net!rill.news.pipex.net!pipex!tank.news.pipex.net!pipex!iafrica.com!not-for-mail
From: Joe Oppon <joe@techno.sanbi.ac.za>
Newsgroups: bionet.software
Subject: Correction ! Nucleotide seqs to Aminoacids
Date: Mon, 07 Apr 1997 14:16:01 +0300
Organization: sanbi
Lines: 26
Message-ID: <3348D771.59E2@techno.sanbi.ac.za>
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-- 
Should have read "which translates nucleotide seq to aminoacids"



Very sorry.












   ************************************************
   *    Joseph Cruick_Shank Oppon                          
   *    South African Bioinformatics Institute            
   *    University of The Western Cape                   
   *    Bellville. South Africa                         
   *    Tel: 0027 (021) 959 3645                       
   *    http://techno.sanbi.ac.za/~joe                
   ************************************************

From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news.maxwell.syr.edu!nntp.uio.no!uninett.no!due.unit.no!usenet
From: Ingar Pareliussen <ajuga@nvg.ntnu.no>
Newsgroups: bionet.plants,bionet.software,comp.sys.handhelds,comp.sys.palmtops
Subject: Using handheld computers in ecological field work
Date: Mon, 07 Apr 1997 15:04:44 +0200
Organization: The Norwegian University of Science and Technology
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Xref: biosci bionet.plants:14958 bionet.software:18300 comp.sys.handhelds:19320 comp.sys.palmtops:71059

I wonder if there was anyone that had used Psion 3c, USR pilot or
similar computers in ecological field work. 
This summer I am going to perform a plant abundance mesurements and 
need a reliable palmtop that can run a simple spreadsheet program,
(one colomn with latin name and 18 columns behind for ecological data 
and about 100 sutch entries pr. day), easy to use, low power consumption
and weather hardy.

From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!ais.net!uunet!in3.uu.net!137.208.127.3!newsfeed.wu-wien.ac.at!usenet
From: bunka@i112pc09.vu-wien.ac.at (Sebastian Bunka)
Newsgroups: bionet.software
Subject: Re: software for predicting antigenesity
Date: 7 Apr 1997 07:53:55 GMT
Organization: Vet. University Vienna
Lines: 45
Message-ID: <5ia96j$hji@cantine.wu-wien.ac.at>
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In article <9704062241.AB28999@mail>,
	congjy@MAIL.TSINGHUA.EDU.CN (Jinyang Cong) writes:
> Hi, I would appreciate very much if someone can tell me where I can get a 
> software to analyze a amino acid sequence of any protein to predict its 
> antigenic epitopes. I am working at using synthetic peptides as antigens to 
> make monoclonal antibodies. This kind of software is very useful for me. Any 
> information would be welcome.
>     Cong, JY 
> 
I know of 2 or three DOS programs that analyse an AA sequence
using the Chou and Frasman algorythms.
You can find 1 or two at ftp.bio.indiana.edu in the
pub/molbio... subdirs, ibmpc, "seqaid.uue", "sqaid381.zip"
and maybe prograph. see also

(91)sunsite.unc.edu

     91  /pub/academic/biology/molbio/ibmpc
       -r--r--r--    4788         23:00:00 12 May 1993 GMT     prograph.zip

(113)bioinformatics.weizmann.ac.il

     113  /pub/software/dos
       -r--r--r--    83354        01:00:00 02 Nov 1993 GMT     predict.exe

(134)ftp.jussieu.fr

     134  /pub16/pc/garbo/math
       -r--r--r--    26785        23:00:00 20 May 1989 GMT     predict.zip

(135)ftp.cnr.it

     135  /pub/PC-IBM/garbo.uwasa.fi/math
       -r--r--r--    1289220      21:05:00 03 Aug 1996 GMT     predict.zip

Hope this helps, SWB
-- 

;-)
------------------------------------------------------------------------
Sebastian Bunka                 ph. (+43-1) 250 77 4208
Institute of                    FAX (+43-1) 250 77 4290
Medical Chemistry               email: Sebastian.Bunka@vu-wien.ac.at
University of Veterinary Medicine - Vienna - Austria
------------------------------------------------------------------------

From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!news-out.communique.net!communique!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!dispatch.news.demon.net!demon!fido.news.demon.net!demon!newsgate.unisource.nl!news.unisource.nl!xs4all!not-for-mail
From: marker@xs4all.nl (Niels Groot)
Newsgroups: bionet.software
Subject: Re: Sequence analysis software
Date: 7 Apr 1997 20:45:43 GMT
Organization: XS4ALL, networking for the masses
Distribution: world
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In article <5i0e0j$ait$1@sparcserver.lrz-muenchen.de>, 
bmeister@lmb.uni-muenchen says...
>
>Dear all,
>
>we are looking for a DNA sequence analysis program, similar to the MAC
>program DNA Strider, which runs under Windows and is public domain or
>not overly expensive.
>
>Any suggestions?
>
>Thanks
>
>Ralf Baumeister
>
>bmeister@lmb.uni-muenchen.de
>
You could take a look at SeqSearch v1.1 for Windows at 
http://www.xs4all.nl/~marker.

I should include a disclaimer since I'm one of the authors..

Regards

Niels Groot


From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!CIFN.UNAM.MX!amedrano
From: amedrano@CIFN.UNAM.MX (Arturo Medrano)
Newsgroups: bionet.software
Subject: Re: Code for nucleotide translation to ptn.
Date: 7 Apr 1997 08:17:48 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 67
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <Pine.SOL.3.95.970407090216.18672B-100000@uxmal>
References: <3348D527.15FB@techno.sanbi.ac.za>
Reply-To: Arturo Medrano <amedrano@cifn.unam.mx>
NNTP-Posting-Host: net.bio.net

   What platform do you want the source code for?  I wrote a C++ code for
windows 3.1, which obtains an amino acid sequence from a DNA sequence
stored in a data base FoxPro-compatible. 
 
Is this useful to you?

                                                     Best regards
                                                       Arturo

___
Luis Arturo Medrano Soto
Computational Biology
Nitrogen Fixation Research Center
CIFN-UNAM P.O Box 565-A
Cuernavaca, Morelos Mexico 62100
Tels:
 (VOICE)  527-313-2063
 ( FAX )  527-317-5581
E-mail:   AMedrano@cifn.unam.mx
WWWS:     http://www.cifn.unam.mx

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_/_/_/  _/_/_/  _/        _/      _/  
_____________________________________________


On Mon, 7 Apr 1997, Joe Oppon wrote:

> -- I am looking for a source coder for any program ...could be
> 
>   the gcg program which translates amino seq to protein seq or vice 
> 
>   versa. The simpler , the better. Meanwhile anything goes.
> 
> 
>   Ooops ! I forgot; better still if it is in C or C++ 
> 
>   Thanks.
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
>    ************************************************
>    *    Joseph Cruick_Shank Oppon                          
>    *    South African Bioinformatics Institute            
>    *    University of The Western Cape                   
>    *    Bellville. South Africa                         
>    *    Tel: 0027 (021) 959 3645                       
>    *    http://techno.sanbi.ac.za/~joe                
>    ************************************************
> 
> 




From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!dispatch.news.demon.net!demon!fido.news.demon.net!demon!news2.euro.net!news.euro.net!usenet
From: mbleeker@euronet.nl (Marco Bleeker)
Newsgroups: bionet.plants,bionet.software,comp.sys.handhelds,comp.sys.palmtops
Subject: Re: Using handheld computers in ecological field work
Date: 7 Apr 1997 22:24:49 GMT
Organization: EuroNet Internet
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On Mon, 07 Apr 1997 15:04:44 +0200, Ingar Pareliussen <ajuga@nvg.ntnu.no>
wrote:

>I wonder

I use a Psion series 3A (2 MB RAM) with a database of 2100 species names. That
is about the max the database can handle at a (barely) acceptable performance.
I haven't tried the spreadsheet yet with such a large number of lines, but I
suppose the max would be about the same. The spreadsheet is quite powerfull (as
opposed to the database) and the 18 columns you mention should not be a problem
I think. The Psion 3A is perhaps not very waterproof. Battery life is great
though.
 
Success, Marco
-- 
<mbleeker@euronet.nl>------------------<Marco Bleeker, Amsterdam, NL>
<CHEZ MARCO'S BOTANY PAGES>---<http://www.euronet.nl/users/mbleeker/>
<Plants Programs Pictures>------------------------------<nl-en-de-fr>

From owner-software@net.bio.net Sun Apr 06 23:00:00 1997
Path: biosci!agate!howland.erols.net!rill.news.pipex.net!pipex!tank.news.pipex.net!pipex!iafrica.com!not-for-mail
From: Joe Oppon <joe@techno.sanbi.ac.za>
Newsgroups: bionet.software
Subject: Code for nucleotide translation to ptn.
Date: Mon, 07 Apr 1997 14:06:15 +0300
Organization: sanbi
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-- I am looking for a source coder for any program ...could be

  the gcg program which translates amino seq to protein seq or vice 

  versa. The simpler , the better. Meanwhile anything goes.


  Ooops ! I forgot; better still if it is in C or C++ 

  Thanks.













   ************************************************
   *    Joseph Cruick_Shank Oppon                          
   *    South African Bioinformatics Institute            
   *    University of The Western Cape                   
   *    Bellville. South Africa                         
   *    Tel: 0027 (021) 959 3645                       
   *    http://techno.sanbi.ac.za/~joe                
   ************************************************

From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!news.apfel.de!news-fra1.dfn.de!news-ge.switch.ch!news-zh.switch.ch!rzunews.unizh.ch!newsadm
From: Rolf Kocherhans <rolfk@vetvir.unizh.ch>
Newsgroups: bionet.software
Subject: Free practical programs for molecular biologists !!!
Date: Tue, 08 Apr 1997 15:19:21 +0100
Organization: University of Zurich
Lines: 49
Message-ID: <334A53E9.4677@vetvir.unizh.ch>
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I wrote a few practical and simple to use programs which facilitate your
daily work in the lab such as predicting the size of DNA fragments after
digestion (graphical) with restriction enzymes.

I would like to make these programs accessible to a broad user group by
the Internet. All programs have been tested on MacOS and Windows95.

My programs are accessible over the WWW and made functional using
Netscape 2.x or Internet Explorer 2.x or higher in association with a
free plugin which you have to download and install first.

This is what you do:

- Download the Roadster plugin

http://www.unizh.ch/vetvir/plugin.html)

install it on your computer.


- Then connect to:

http://www.unizh.ch/vetvir/programs.html

That's it !!

These are my programs which make your live as a molecular biologist
easier !

Find here a few more examples or my programs:

a. Digest Preview:
Enter the size(s) of your DNA fragment(s) and see their migration
pattern
in a virtual gel in comparison to a 1 kb ladder.

b. Adapter Design:
Helps to create in frame adapters in order to link incompatible DNA ends
together.

c. Dilution Calculator:
Does all the calculations when you have to make up solutions

There are many other programs such as Oligo Tm, Compatible ends etc.

Please have a look, comments are welcome!

Have fun
Rolf Kocherhans   mailto:rolfk@vetvir.unizh.ch

From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!ais.net!news.stealth.net!newsfeed.de.ibm.net!ibm.net!02-newsfeed.univie.ac.at!03-newsfeed.univie.ac.at!mail.boku.ac.at!news
From: Andreas Wernitznig <h8760592@edv1.boku.ac.at>
Newsgroups: bionet.software
Subject: Re: Phyllip Interleave Format?
Date: Tue, 08 Apr 1997 17:37:23 +0200
Organization: Univ. for Agriculture
Lines: 9
Message-ID: <334A6633.24AA@edv1.boku.ac.at>
References: <MPG.da2695c2f899e2e9896a2@nntp.ix.netcom.com>
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Marc A. Goldstein wrote:
>         Could someone please direct me to a reference that would describe
> the Phyllip Interleave format used by various sequence alignment
> programs? I am curious to know how to build a file in this format.


Have a look in the Phylip manual. There is a short description of the
Interleave format.
Andreas Wernitznig

From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!news.apfel.de!news-fra1.dfn.de!news-koe1.dfn.de!main.Germany.EU.net!Dortmund.Germany.EU.net!news.gsf.de!news
From: Kerstin Quandt <quandt@gsf.de>
Newsgroups: bionet.software
Subject: SW to detect correlated TF binding sites
Date: Tue, 08 Apr 1997 17:07:22 +0200
Organization: GSF Forschungszentrum
Lines: 36
Message-ID: <334A5F2A.167E@gsf.de>
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We would like to announce the availability of the online version of
the programs FastM and ModelInspector, tools for detection of correlated
transcription factor binding sites in DNA sequences (including
databases).

FastM builds a so-called model from the information of
- which two binding sites are involved
- their strand orientation (with respect to each other)
- and a distance range between the two binding sites.

ModelInspector then uses this FastM-model to scan either a given
DNA sequence or a selected GenBank section for matches to the model.
This allows fast verification whether a pair of binding sites is
really characteristic for the sequence you are analyzing.

You can use FastM/ModelInspector interactively via WWW at

        http://www.gsf.de/cgi-bin/fastm.pl

More information and an example can be found at

        http://www.gsf.de/biodv/fastm.html
 
All parameters for the programs can be set via the WWW-form,
you can select a GenBank section or enter your own sequence to be
scanned for matches.
The resulting output will be mailed to you.

The binding site library used by FastM is based on the latest 
release 3.1 of the TRANSFAC database
(http://transfac.gbf-braunschweig.de/TRANSFAC).

-- 
Kerstin Quandt                         |  email:    quandt@gsf.de
GSF - National Research Centre for Environment and Health
85764 Neuherberg,  F.R.Germany

From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!GENECODES.COM!jimgalt
From: jimgalt@GENECODES.COM (Jim Galt)
Newsgroups: bionet.software
Subject: Manipulating ABI Chromatogram files
Date: 8 Apr 1997 13:32:18 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 41
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <v03007807af705b83176c@[206.252.3.18]>
NNTP-Posting-Host: net.bio.net

To Chris Cunningham:

In response to your query about capturing ABI trace file images for making
figures, I would recommend the following technique, which I have been using
recently:

Go to the Ambrosia Software shareware web site at http://www.ambrosiasw.com
and download a demo copy of "Snapz Pro". This screen capture utility allows
much more flexibility than the standard Macintosh cmd-shift-3 screen
capture. For instance, you can capture just a selection of the window by
dragging a marquee (which is what you will probably want to do). It can
also capture windows or menus. Install this control panel, and restart your
Mac. (Don't forget to pay your shareware fees!)

1. Using Sequencher, select the region of the trace file(s) you want to
view by highlighting the DNA sequence.
2. Click on the "Show Chromatograms" button in the menubar.
3. Alter the size of the viewing window and the scaling of the peaks on the
trace file to suit your needs.
4. I would then click on a base  outwith the region of interest, to remove
the highlighting from the selected sequence.
5. Type the keystroke to activate Snapz Pro (I think it is cmd-shift-3 by
default) and choose the "Selection" tool.
6. Decide how you want the picture to be captured - I have had variable
success with "Clipboard", and more reliable results with "Screen Snapz".
The latter saves it as a SimpleText file, which you then open up, select
all, copy and paste into a drawing program (I use Superpaint, for instance).
7. Then you can erase parts of the picture, add legends, etc. and prepare
the final figure the way you want.

I hope this helps you get what you want. Please let me know if it does, or
if you have any questions.

Sincerely,

Jim Galt

P.S. - I should also mention that I am originally from Glasgow, and I have
been in the US for 9 years now.



From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!news.maxwell.syr.edu!news.apfel.de!fu-berlin.de!unlisys!blackbush.xlink.net!news-ge.switch.ch!news.bme.hu!news.iif.hu!kokiux.koki.hu!f-guest
From: Guest of Freund Group <f-guest@koki.hu>
Newsgroups: bionet.software
Subject: Patch clamp software
Date: Tue, 8 Apr 1997 19:25:29 +0200
Organization: IIF
Lines: 17
Message-ID: <Pine.OSF.3.95.970408192410.24551B-100000@kokiux.koki.hu>
NNTP-Posting-Host: kokiux.koki.hu
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=US-ASCII



---------- Forwarded message ----------

Did anyone heard something about the patch clamp acquisitioning and 
analyzing software DEMPSTER.
If my infos are correct, thats probably the best FREE software in the 
'market', but I can't find it on the net :(
By the way, does anyone have a cool software of the type and FREE ?

Any info is waited with open arms at RANCZ@LUDENS.ELTE.HU
				  or F-GUEST@KOKIUX.KOKI.HU
Thanx





From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!daresbury!uninett.no!hermod.uio.no!nntp.uio.no!newsfeed.nacamar.de!fu-berlin.de!informatik.tu-muenchen.de!lrz-muenchen.de!wap18.zi.biologie.uni-muenchen.de!strimmer
From: Korbinian Strimmer <strimmer@zi.biologie.uni-muenchen.de>
Newsgroups: bionet.software
Subject: Version 3.1 of PUZZLE available
Date: Tue, 8 Apr 1997 10:37:23 +0200
Organization: [posted via] Leibniz-Rechenzentrum, Muenchen (Germany)
Lines: 52
Distribution: world
Message-ID: <Pine.A32.3.95.970408103637.15696B-100000@wap18.zi.biologie.uni-muenchen.de>
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Mime-Version: 1.0
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                              P U Z Z L E

Maximum likelihood analysis for nucleotide and amino acid alignments

Version 3.1
April 1997
Copyright 1995-97 by Korbinian Strimmer and Arndt von Haeseler

Zoologisches Institut, Universitaet Muenchen, Muenchen, Germany


What's new in PUZZLE 3.1:

 *  Much improved user interface to rate heterogeneity (less confusing
    menu, rearranged outfile, additional out-of-range check).
    
 *  Possibility to read rooted input trees
    (automatic removal of basal bifurcation).
 
 *  Computation of average distance between all pairs of sequences.
    
 *  Fix of a bug that caused PUZZLE 3.0 to crash on some systems (DEC Alpha).
    
 *  Cosmetic changes in program and documentation.


PUZZLE is an application to reconstruct phylogenetic trees from molecular
sequence data by maximum likelihood. It implements a fast tree search
algorithm (quartet puzzling) that allows analysis of large data sets and
automatically assigns estimations of support to each internal branch. Rate
heterogeneity (invariable sites plus Gamma distributed rates) is
incorporated in all models of substitution available (nucleotides: TN, HKY,
F84, and submodels; amino acids: Dayhoff, JTT, mtREV24). All model
parameters including rate heterogeneity can be estimated from the data by
maximum likelihood. PUZZLE also computes pairwise maximum likelihood
distances as well as branch lengths for user specified trees. In addition,
PUZZLE offers a novel method, likelihood mapping, to investigate the support
of internal branches without computing an overall tree.

PUZZLE is available free of charge from

  http://www.zi.biologie.uni-muenchen.de/~strimmer/puzzle.html (PUZZLE home page)
  ftp://ftp.ebi.ac.uk/pub/software (European Bioinformatics Institute)
  ftp://ftp.pasteur.fr/pub/GenSoft (Institut Pasteur)

PUZZLE is written as an ANSI C program. This means that it will run on most
personal computers and workstations if compiled by an appropriate C
compiler. Precompiled executables are available for MacOS and MS-DOS. UNIX
and VMS makefiles are also provided.



From owner-software@net.bio.net Mon Apr 07 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!su-news-hub1.bbnplanet.com!news.bbnplanet.com!supernews.com!news
From: "Rob Halvorson" <rkhal@delrio.com>
Newsgroups: bionet.plants,bionet.software,comp.sys.handhelds
Subject: Re: Using handheld computers in ecological field work
Date: 8 Apr 1997 20:33:41 GMT
Organization: All USENET -- http://www.Supernews.com
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X-Newsreader: Microsoft Internet News 4.70.1155
Xref: biosci bionet.plants:14977 bionet.software:18310 comp.sys.handhelds:19365

put an HP200LX in a ziplock bag.  Meets all your requirements.

Ingar Pareliussen <ajuga@nvg.ntnu.no> wrote in article
<3348F0EC.2AA9@nvg.ntnu.no>...
> I wonder if there was anyone that had used Psion 3c, USR pilot or
> similar computers in ecological field work. 
> This summer I am going to perform a plant abundance mesurements and 
> need a reliable palmtop that can run a simple spreadsheet program,
> (one colomn with latin name and 18 columns behind for ecological data 
> and about 100 sutch entries pr. day), easy to use, low power consumption
> and weather hardy.
> 

From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!cpk-news-hub1.bbnplanet.com!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!hermes.sovam.com!sovam!demos!news.rcom.ru!infopro!not-for-mail
From: "Yuriy Eizner" <eizner@isc.nw.ru>
Newsgroups: bionet.software
Subject: Re: statistics and pharmacology
Date: 9 Apr 1997 07:37:17 GMT
Organization: WinWare Unlimited
Lines: 21
Message-ID: <01bc43d9$25b95b40$af01f2c3@eizner>
References: <5i2o8a$jj8@rc1.vub.ac.be>
NNTP-Posting-Host: dialup-126.infopro.spb.su
X-Newsreader: Microsoft Internet News 4.70.1155


Philipp Lebran wrote:

> Does anyone know of software that will calculate regerssion parameters
and
> ED50 value of dose-response curves? 
> 
> Currently I'm doing it by hand (by hand in Excel, that is) but I'm not
sure 
> at all of my results.
> 
> Thanks,
> Philippe
> 

Hi,  Philipp

Try to use  "Origin" .   This product is convenient.

Yurii


From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!agate!howland.erols.net!cam-news-hub1.bbnplanet.com!cpk-news-feed3.bbnplanet.com!news.bbnplanet.com!es.dupont.com!topgun.es.dupont.com!millermac.es.dupont.com!user
From: millertj@esvax.dnet.dupont.com (T Miller)
Newsgroups: bionet.software
Subject: Re: Manipulating ABI Chromatogram files
Date: Wed, 09 Apr 1997 10:19:03 -0400
Organization: Dupont
Lines: 26
Distribution: world
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References: <v03007807af705b83176c@[206.252.3.18]>
NNTP-Posting-Host: millermac.es.dupont.com

In article <v03007807af705b83176c@[206.252.3.18]>, jimgalt@GENECODES.COM
(Jim Galt) wrote:

> To Chris Cunningham:
> 
> In response to your query about capturing ABI trace file images for making
> figures, I would recommend the following technique, which I have been using
> recently:
> 
> Go to the Ambrosia Software shareware web site at http://www.ambrosiasw.com
> and download a demo copy of "Snapz Pro". This screen capture utility allows
> much more flexibility than the standard Macintosh cmd-shift-3 screen
> capture. For instance, you can capture just a selection of the window by
> dragging a marquee (which is what you will probably want to do). It can
> also capture windows or menus. Install this control panel, and restart your
> Mac. (Don't forget to pay your shareware fees!)
> 
 You might want to try Mainstay's Capture (now called Captivate, I think).
It is a commercial package and used for screen captures and later
viewing/saving. 
Regards, Tom.

Standard disclaimers....

-- 
Opinions are my own and not of my employer.

From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!news.sgi.com!news.maxwell.syr.edu!ott.istar!news.istar.net!tor.istar!east.istar!ftn.net!passport.ca!news
From: Ryan Burns <webmaster@fieldworker.com>
Newsgroups: bionet.plants,bionet.software,comp.sys.handhelds,comp.sys.palmtops
Subject: Re: Using handheld computers in ecological field work
Date: Wed, 09 Apr 1997 09:59:23 -0400
Organization: Fieldworker
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References: <3348F0EC.2AA9@nvg.ntnu.no>
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Xref: biosci bionet.plants:14989 bionet.software:18313 comp.sys.handhelds:19394 comp.sys.palmtops:71227

FieldWorker software running on a Newton allows you to collect all your
field data and link it to GPS position readings.  You can customize your
database and easily export the data to any desktop program on a PC or
MAC.  Multiple data types include sliders, pick lists, and check boxes.
In the upcoming Pro version, a sketch pad will also be available, as
well as a full relational database.  

Contact me at webmaster@fieldworker.com or visit our website at
http://www.fieldworker.com/ for more information.

-- 
================================================
Ryan Burns, Webmaster                <webmaster@fieldworker.com>
Download FieldWorker 2.3 Demo!..at http://www.fieldworker.com
Navigation, Differential GPS, Offset, Relational Map, Multi-lingual!
   FieldWorker    -    Handheld PC data collection linked to GPS
-- FieldWorker Products Ltd.--               Tel: +1 416 483 3485
================================================

From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!newsin.iconnet.net!news-xfer.netaxs.com!news.maxwell.syr.edu!nntp.uio.no!uninett.no!due.unit.no!usenet
From: Hans Stenöien <hans.stenoien@vm.unit.no>
Newsgroups: bionet.software
Subject: Arlequin ver.1.0 and RAPD-PCR
Date: Wed, 09 Apr 1997 12:57:21 +0200
Organization: The Norwegian University of Science and Technology
Lines: 17
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Dear all:

I am doing RAPD-PCR analyses on two Sphagnum (peat-moss) species. I am
using the haploid gametophores in the analyses. The software Arlequin
ver. 1.0 does not accept RAPD-PCR data from diploids. However, shouldn't
it be possible to define my data as "RFLP haplotypic data" and carry out
ordinary population genetic analyses using this software?

Thank you.

Sincerely,
Hans Stenøien

Inst. of Natl. Hist.
Museum of Natl. Hist. & Arch.
Norwegian University of Science and Technology
N-7004 Trondheim, Norway

From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!uthct.edu!wu
From: wu@uthct.edu
Newsgroups: bionet.software
Subject: ANNOUNCE: GeneFIND Server for protein family identification
Date: 9 Apr 1997 08:45:01 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 40
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9704091546.AA18297@diana.uthct.edu>
NNTP-Posting-Host: net.bio.net


The Bioinformatics Research Group of the University of Texas Health Center at
Tyler is pleased to announce the availability of its GeneFIND Server for
protein family identification at:

     http://diana.uthct.edu/genefind.html

GeneFIND (Gene Family Identification Network Design) is an integrated database
search system that combines several search/alignment tools and ProClass
database (http://diana.uthct.edu/proclass.html) to provide rapid and sensitive 
search results with enriched family information.  Multi-level filters are used, 
starting with the fastest MOTIFIND neural networks, followed by BLAST search, 
SSEARCH (Smith-Waterman) sequence alignment, and motif pattern search.  

The server currently provides large-scale on-line identification of query 
sequences for 942 protein families.  Search results are returned as HTML 
documents showing global and motif scores, alignment to best matched members of 
all possible ProSite protein groups and PIR superfamilies, motif pattern match, 
as well as links to corresponding ProClass family records.

Please cite the following reference in publications that benefit from the
GeneFIND family identification system:

     Wu, C. H., Zhao, S., Chen, H. L., Lo, C. J. and McLarty, J. (1996). Motif
     identification neural design for rapid and sensitive protein family
     search. CABIOS, 12(2), 109-118.

Please visit our site and send suggestions and comments to me at wu@uthct.edu.
Also contact me directly if you are interested in obtaining a copy of the
GeneFIND software program.  I am looking forward to hearing from you!


Cathy Wu, Ph.D.
Associate Professor of Biomathematics
University of Texas Health Center at Tyler
P. O. Box 2003, Tyler, TX 75710
E-Mail   : wu@uthct.edu
Fax      : (903) 877-5914
Phone    : (903) 877-7962
WWW URL  : http://diana.uthct.edu/~wu 

From owner-software@net.bio.net Tue Apr 08 23:00:00 1997
Path: biosci!agate!howland.erols.net!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!news.maxwell.syr.edu!metro.atlanta.com!cssun.mathcs.emory.edu!hubcap.clemson.edu!sc.edu!usenet
From: Dean Pentcheff <dean@tbone.biol.sc.edu>
Newsgroups: bionet.plants,bionet.software,comp.sys.handhelds,comp.sys.palmtops
Subject: Re: Using handheld computers in ecological field work
Date: 09 Apr 1997 18:30:48 -0400
Organization: Univ. of South Carolina, Columbia
Lines: 40
Sender: dean@nauplius.psc.sc.edu
Distribution: inet
Message-ID: <m1lo6ru8vb.fsf@nauplius.psc.sc.edu>
References: <3348F0EC.2AA9@nvg.ntnu.no>
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Xref: biosci bionet.plants:14996 bionet.software:18316 comp.sys.handhelds:19429 comp.sys.palmtops:71284

Ingar Pareliussen <ajuga@nvg.ntnu.no> writes:
> I wonder if there was anyone that had used Psion 3c, USR pilot or
> similar computers in ecological field work. 
> This summer I am going to perform a plant abundance mesurements and 
> need a reliable palmtop that can run a simple spreadsheet program,
> (one colomn with latin name and 18 columns behind for ecological data 
> and about 100 sutch entries pr. day), easy to use, low power consumption
> and weather hardy.

I recently (4 months ago) set up an HP200LX (1 Mb memory) for use by
people collection bird abundance observations from shipboard in
Antarctica.  I was very impressed with it.

It's a little DOS machine, with a built-in copy of Lotus 1-2-3.
There's a layer of HP graphical software which can be disabled, saving
memory.  You can repartition the 1 Mb of memory between program RAM
and RAM disk as appropriate for your use.  

The unit is small and quite rugged.  It has a small but usable
keyboard (not for touch-typing, but fine for data entry, particularly
if you set up useful one-key spreadsheet macros).  It runs off two AA
batteries for several weeks.

Communications are over a serial port (signals are standard RS232, but
the cable connector is weird - buy HP's "Connectivity Kit", or build
your own cable and use standard old DOS serial communications
packages).  It's also got a PCMCIA (PC Card) slot that can use memory
cards.  

All in all, quite a useful little beastie.  I recommend it -
particularly since it's now a model or two behind the most recent
releases, you can probably buy two or three used ones and have spares
(which is a MUST for field work).  

-Dean
-- 
N. Dean Pentcheff   <pentcheff@acm.org>   WWW: http://tbone.biol.sc.edu/~dean/
Biological Sciences, Univ. of South Carolina, Columbia SC 29208 (803-777-3936)
PGP ID=768/22A1A015 Keyprint=2D 53 87 53 72 4A F2 83  A0 BF CB C0 D1 0E 76 C0 
Get PGP keys and information with the command: "finger dean@tbone.biol.sc.edu"

From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!biochem.umass.edu!bscott
From: bscott@biochem.umass.edu (Brian Scott)
Newsgroups: bionet.software
Subject: Free molecular visualization workshops for profs
Date: 9 Apr 1997 17:34:28 -0700
Organization: University of Massachusetts
Lines: 54
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <334C354C.6136@biochem.umass.edu>
Reply-To: bscott@biochem.umass.edu
NNTP-Posting-Host: net.bio.net

Free Workshops on Molecular Visualization
for Undergraduate Bioscience Teaching
Amherst MA -- Summer, 1997-8

Understanding the three-dimensional structures of proteins, DNA,
RNA, and their interactions is difficult from flat pictures, yet
grasping structure is important to understanding function.  Free
software is now available which displays attention-grabbing 3D
animated images of biological molecules in depth-cued spacefilling
color. RasMol (http://www.umass.edu/microbio/rasmol), which
works on Windows or Macs, encourages self-directed exploration.
Chime (http://www.umass.edu/microbio/chime) allows annotated
preset views of molecules to be delivered as web tutorials.

Free, hands-on workshops will be held this summer at the University
of Massachusetts in Amherst to prepare college faculty with no prior
experience to use molecular visualization in their classes.
Participants will travel to the Amherst campus on three separate
days (two this summer, one the following summer), and are
responsible for their own travel expenses (and therefore are
expected primarily from the Northeastern USA). Overnight
accomodations will be provided free to those needing them (based on
distance traveled).  Participants will be expected to incorporate
molecular visualization into their teaching, and to mentor two
faculty colleagues at their home institution.

The workshops will be led by Eric Martz, a Professor in the
Department of Microbiology.  Martz has innovated molecular structure
tutorials which are in use throughout the USA and in dozens of other
countries.  The web site he created (see above) was visited by
40,000 people in 1996.

1997 dates are June 17 and 30 (workshop A), or June 19 and July 2
(workshop B).  Workshops A and B also meet for one day in late June
1998.  To obtain more detailed information and a REGISTRATION
FORM, visit

http://www.umass.edu/microbio/rasmol/workshop.htm

or FAX a request to 413-545-1578,
or email a request to emartz@microbio.umass.edu.

Supported by the National Science Foundation (Undergraduate Faculty
Enhancement, Division of Undergraduate Education) and the University
of Massachusetts.
/* - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Eric Martz, Professor (Immunology), Dept Microbiology, Univ
Massachusetts,
Amherst MA US 01003-5720 413-545-2325 FAX:545-1578.
RasMol Home Page, http://www.umass.edu/microbio/rasmol
Other web projects listed at
http://www.umass.edu/microbio/rasmol/em-web.htm
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -*/


From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!daresbury!not-for-mail
From: "Holger Scheib" <hscheib@tebio1.biologie.uni-stuttgart.de>
Newsgroups: bionet.software
Subject: Some questions
Date: 10 Apr 1997 12:00:22 +0100
Lines: 56
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <5iih86$sq@mserv1.dl.ac.uk>
Original-To: molmodel@dl.ac.uk, comp-bio@dl.ac.uk, bio-www@dl.ac.uk, bio-soft@dl.ac.uk,
 hscheib@tebio1.biologie.uni-stuttgart.de

Dear collegues,

my name is Holger Scheib and I am working at the Institute of Technical
Biochemistry at the University of Stuttgart, Germany. Recently, we decided to
get your Grasp software which is a real nice and handy tool and well suited for
my research interests.
I am investigating lipase-triglyceride complexes and would like to calculate
1st the total accessible surface and 2nd the accessible surface for polar as
well as for hydrophobic amino acid residues.
So far, I performed several calculations leading to the following results:

total surface            unpolar surface                  polar surface
11007 (4220)             3548 (1721)                      3434 (1434)
11002 (4220)             3519 (1721)                      3551 (1434)
10945 (4220)             3540 (1721)                      3463 (1434)
11086 (4220)             3554 (1721)                      3454 (1434)

The values on the left of each column are the surface sizes in squared
angstroems. The values in brackets represent the number of atoms that have been
considered for the surface calculation. I performed the calculations as
mentioned in your Manual.
Here my questions in detail:

Why isn't the accessible total surface the sum of accessible polar and unpolar
surface? Or why are roughly 1000 atoms ignored for these calculations? What
happens to the rest?

Are Hydrogens used for the calculation of a surface or will Grasp sort them out
before calculating the surface?

Is the accessible surface calculated from the center of the (standard) 1.4 A
probe or from the probe surface?

Are substrate VdW radii automatically set or accepted by Grasp or will I have
to manually adding them to some file?

Is there a possibility to color the surface by hydrophobicity?

It would be great to hear from you soon.
Thanx a bunch in advance.
Sincerely,

Holger

-- 
*******************************************************
* Dipl. Chem. M. Sc. Holger Scheib                    *
* Institut fuer Technische Biochemie                  *
* Universitaet Stuttgart                              *
* Allmandring 31                                      *
* 70569 Stuttgart                                     *                           
*                                                     *
* Tel.:  (0711) 685-7481                              *
* Fax.:  (0711) 685-3196                              *                          * email: hscheib@tebio1.biologie.uni-stuttgart.de     *
* www: http://www.itb.uni-stuttgart.de:8080/home.html *
*******************************************************

From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!agate!spool.mu.edu!uwm.edu!news-peer.gsl.net!howland.erols.net!rill.news.pipex.net!pipex!oleane!jussieu.fr!not-for-mail
From: Michel SEIGNEURET <michel@biophy.jussieu.fr>
Newsgroups: bionet.software
Subject: alignment software
Date: 10 Apr 1997 09:30:57 GMT
Organization: Universites Paris VI/Paris VII - France
Lines: 16
Message-ID: <5iic0h$39s$1@vishnu.jussieu.fr>
NNTP-Posting-Host: mood.biophy.jussieu.fr
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X-URL: news:bionet.software

Dear Collegues.
My question is probably trivial but I am a newcomer to this field and
I could not find a FAQ on this.
I currently often do BLAST or FASTA searches of particular protein sequences 
against the SWISSPROT or PIR databases though the WWW. The problem is that the
internet connection of my lab is slow. I am thus thinking of doing such
searches locally after downloading the complete database. Could somebody
suggest me a freely available software that allows one to do a BLAST or FASTA 
alignment search locally ? 
Thank you in advance.

Michel Seigneuret
Lab. de Biophysique Cellulaire et RMN
Universite Paris 7
France


From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.maxwell.syr.edu!newsfeed.nacamar.de!uunet!in1.uu.net!205.229.48.18!news.fdt.net!news.gwi.net!web.ddp.state.me.us!sol.caps.maine.edu!dartvax.dartmouth.edu!atgw-kip-2-157.dartmouth.edu!user
From: Nick.Morris@Dartmouth.Edu (Nick Morris)
Newsgroups: bionet.software
Subject: Re: alignment software
Date: Thu, 10 Apr 1997 11:34:52 +0100
Organization: Dartmouth College
Lines: 32
Message-ID: <Nick.Morris-1004971134520001@atgw-kip-2-157.dartmouth.edu>
References: <5iic0h$39s$1@vishnu.jussieu.fr>
NNTP-Posting-Host: atgw-kip-2-157.dartmouth.edu

In article <5iic0h$39s$1@vishnu.jussieu.fr>, Michel SEIGNEURET
<michel@biophy.jussieu.fr> wrote:

> Dear Collegues.
> My question is probably trivial but I am a newcomer to this field and
> I could not find a FAQ on this.
> I currently often do BLAST or FASTA searches of particular protein sequences 
> against the SWISSPROT or PIR databases though the WWW. The problem is that the
> internet connection of my lab is slow. I am thus thinking of doing such
> searches locally after downloading the complete database. Could somebody
> suggest me a freely available software that allows one to do a BLAST or FASTA 
> alignment search locally ? 
> Thank you in advance.
> 
> Michel Seigneuret
> Lab. de Biophysique Cellulaire et RMN
> Universite Paris 7
> France

If your internet connection is so slow that you can't do BLAST by WWW then
dowloading the database (if possible?) may take days!

My suggestion would be to do the BLAST searches by e-mail, the results
would then be returned by e-mail.  It may not be quite as user friendly as
the WWW but at least you won't have to sit at the computer waiting for
things to happen. Also, the e-mail can be formatted so that an HTML
document is returned so you can still make use of the direct links to the
protein/DNA entry in the database.

I hope this helps,

Nick

From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ix.netcom.com!news.webspan.net!news-out.internetmci.com!newsfeed.internetmci.com!news.net-master.net!usenet
From: lankford@net-master.net (C. L. Lankford)
Newsgroups: bionet.software
Subject: LANKFORD SCREEN COPY UTILITY v1.7
Date: Thu, 10 Apr 1997 15:51:46 GMT
Organization: NetMaster Internet Services
Lines: 20
Message-ID: <5ij24s$61u@tiger.net-master.net>
NNTP-Posting-Host: s32.net-master.net
X-Newsreader: Forte Free Agent 1.0.82

http://www.net-master.net/~lankford/

LANKFORD SCREEN COPY UTILITY v1.7 - THE must
have utility for automating capture/saving
of screen images with the press of a key.
Support for Windows/CD-ROM/Games/Internet/
OnLine Services to quickly and easily save
ANYTHING you can see to a file, print, etc.
In short, if you can see it on a monitor
display, then this utility can acquire it,
save it to a file, print it, etc.  Designed
for Windows 3.1x/W95.  Requires VBRUN300.DLL

Package includes an uninstall program, so that you can remove the
software easily, if you don't want to keep it.

You can download this package from:
http://www.net-master.net/~lankford/



From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!daresbury!not-for-mail
From: James McInerney <J.McInerney@nhm.ac.uk>
Newsgroups: bionet.software
Subject: Re: alignment software
Date: 10 Apr 1997 14:17:26 +0100
Organization: The Natural History Museum
Lines: 33
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <5iip96$ah5@mserv1.dl.ac.uk>
References: <9741010320.~INN-PPBa00253.bionet-news@dl.ac.uk>
Reply-To: J.McInerney@nhm.ac.uk
MIME-Version: 1.0
Original-To: Bionet Software <bio-software@dl.ac.uk>

Michel SEIGNEURET wrote:
> 
> Dear Collegues.
> My question is probably trivial but I am a newcomer to this field and
> I could not find a FAQ on this.
> I currently often do BLAST or FASTA searches of particular protein sequences
> against the SWISSPROT or PIR databases though the WWW. The problem is that the
> internet connection of my lab is slow. I am thus thinking of doing such
> searches locally after downloading the complete database. Could somebody
> suggest me a freely available software that allows one to do a BLAST or FASTA
> alignment search locally ?
> Thank you in advance.
> 

You can get FastA from:

ftp://ftp.virginia.edu/pub/

you are going to need a beefy computer for big searches, but I like the
package and it does quite a lot of cool things.

regards,

James
-- 
=========
James O. McInerney               email: J.mcinerney@nhm.ac.uk
Senior Scientific Officer,       phone: +44 171 938 9247
Department of Zoology,           Fax:   +44 171 938 9158
The Natural History Museum,
Cromwell Road,                    
London SW7 5BD.                  
=========

From owner-software@net.bio.net Wed Apr 09 23:00:00 1997
Path: biosci!agate!howland.erols.net!news-peer.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!sprint!news.maxwell.syr.edu!news.visi.net!mur2.odyssey.on.ca!news3.sprint-canada.net!roger.interlynx.net!not-for-mail
From: Lars Thomsen <lthomsen@interlynx.net>
Newsgroups: bionet.software
Subject: Re: statistics and pharmacology
Date: Mon, 07 Apr 1997 17:33:22 -0700
Organization: Interlynx
Lines: 24
Message-ID: <33499252.F37@interlynx.net>
References: <5i2o8a$jj8@rc1.vub.ac.be>
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GraphPad Prism and you can download a trial version that will run for 30
days from their webpages.
http://www.graphpad.com/www/welcome.html

You could also try Microcal Origin, but I have both but I think the
other is doing a better job and its easier to use (and its free for 30
days)

SigmaPlot is another possibility I dont know if they have builtin
functions for pharmacology, but I would think so because one of their
commercials is that the have tons and tons of inbuilt equations.

If you are doing whole cell measurements  then I am developing freeware
that will be integrated with GraphPad Prism.

Best Regards

--
Lars Thomsen, MSc PhD
115 South Oval, Hamilton, L8S1R2 Ontario, Canada
tlp +1 905 777 0720 fax +1 905 777 0738
email lthomsen@interlynx.net
homepage http://home.interlynx.net/~lthomsen


From owner-software@net.bio.net Thu Apr 10 23:00:00 1997
Path: biosci!kazusa.or.jp!miyajima
From: miyajima@kazusa.or.jp (Nobuyuki Miyajima)
Newsgroups: bionet.software
Subject: JMGD:Java-based User Interface to the Microbial Genome Database
Date: 11 Apr 1997 00:22:24 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 62
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199704110723.QAA06335@not1.kazusa.or.jp>
NNTP-Posting-Host: net.bio.net

Dear colleagues,

I'd like to introduce you our Java based WWW-Genome tool, JMGD.
You can see examples (Haemophilus influenzae, 
Mycoplasma genitalium, Methanococcus jannaschii) in 

http://www.kazusa.or.jp/jmgd/

Source codes are available. 
============================================================================
JMGD:Java-based User Interface to the Microbial Genome Database
============================================================================
As the rate of progress in the determination of the whole genome 
sequencing of microbial organisms increases, we will need to have 
efficient, ready-to-use tools to publicize the data through WWW as 
soon as we finish the work.  Java-based user interface to the microbial 
genome database (JMGD) can be used for almost any kind of circular 
microbial organisms. We use JMGD for the genome sequencing of 
cyanobacterium we published recently 
(http://www.kazusa.or.jp/cyanobase/map/java/cmap_small/cmap_sm.html).
Java-based highlight-image techniques that were originally developed 
y Jim Graham(Sun Microsystem) are used in JMGD. JMGD includes all the Java 
source codes, perl scripts and the cgi scripts that are also used to blink 
the selected ORFs. The platform-independent aspect of Java makes it 
easily implemented in any machines used such as UNIX 
workstations, Macintosh or Windows computers.

JMGD has been developed under Sybase, but any other database management 
systems can be applied to without substantial modifications.

JMGD is available from:

ftp://ftp.kazusa.or.jp/pub/JMGD/
http://www.kazusa.or.jp/jmgd/


0. Prerequisites:

   * software

         perl    5.003 or later
          JDK    1.02  (1.1 is not supported in the current release)
      sybperl    2.06  or later  (http://www.perl.com/perl/CPAN/authors/id/MEWP)

   * OS   

      Solaris    2.5 or later
         OSF1    3.2 or later

   * DBMS (Database Management System)

      SQL Server   10/11 or any other DBMSs can be used.

-----------------------------------------------
Nobuyuki Miyajima
Kazusa DNA Research Institute
Department of Genome Informatics,
Chief Researcher

1532-3 Yana, Kisarazu, Chiba 292, Japan
TEL:  +81-438-52-3917 FAX:  +81-438-52-3918
E-mail:  miyajima@kazusa.or.jp

From owner-software@net.bio.net Thu Apr 10 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!news-peer.gsl.net!news-peer.sprintlink.net!news.sprintlink.net!sprint!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!paladin.american.edu!news.ecn.uoknor.edu!munnari.OZ.AU!metro!metro!news
From: Phillip Robinson <phrobins@mail.usyd.edu.au>
Newsgroups: bionet.software
Subject: Re: alignment software
Date: Fri, 11 Apr 1997 17:15:35 +1000
Organization: Information Technology Services, The University of Sydney, NSW, Australia
Lines: 19
Distribution: inet
Message-ID: <334DE517.35F9@mail.usyd.edu.au>
References: <5iic0h$39s$1@vishnu.jussieu.fr>
NNTP-Posting-Host: modem-b-56.mp.usyd.edu.au
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X-Mailer: Mozilla 3.0 (Win95; I)

Michel SEIGNEURET wrote:
> 
> Dear Collegues.
> My question is probably trivial but I am a newcomer to this field and
> I could not find a FAQ on this.
> I currently often do BLAST or FASTA searches of particular protein sequences
> against the SWISSPROT or PIR databases though the WWW. The problem is that the
> internet connection of my lab is slow. I am thus thinking of doing such
> searches locally after downloading the complete database. Could somebody
> suggest me a freely available software that allows one to do a BLAST or FASTA
> alignment search locally ?
> Thank you in advance.

I believe you need the PC-based Windows program AnTheProt.  Available
from: http://www.ibcp.fr:80/antheprot.html

At least, I use it and think it is magic.

Phil					Sydney, Australia

From owner-software@net.bio.net Thu Apr 10 23:00:00 1997
Path: biosci!daresbury!uninett.no!nntp.uio.no!newsfeeds.sol.net!news.maxwell.syr.edu!news.msfc.nasa.gov!bcm.tmc.edu!news
From: Kim Worley <kworley@bcm.tmc.edu>
Newsgroups: bionet.software
Subject: Re: alignment software
Date: Fri, 11 Apr 1997 09:33:05 -0500
Organization: Baylor College of Medicine
Lines: 31
Message-ID: <334E4BA1.20CA@bcm.tmc.edu>
References: <5iic0h$39s$1@vishnu.jussieu.fr>
NNTP-Posting-Host: dot.imgen.bcm.tmc.edu
Mime-Version: 1.0
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Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0 (X11; I; SunOS 5.5 sun4m)
To: Michel SEIGNEURET <michel@biophy.jussieu.fr>

To avoid having to wait for the Web searches to complete, I
recommend the Search Launcher Batch Client, a Unix and Macintosh
application that automatically 1) reads-in sequences from one or more
input files, 2) runs a specified search in the background for each
sequence, and 3) stores each of the search output files as individual
HTML documents directly on a user's system.  The result files can be
browsed at any later date using Mosaic or Netscape.  For users who wish
to perform a particular search on a number of sequences at a 
time, the batch client provides complete access to the Search Launcher
with the convenience of batch submission and background operation,
greatly simplifying and expediting the search process.
	Accessing Web based search tools via the Search Launcher Batch Client
provides access to the (very) large sequence databases that are changing
daily, without having to store and maintain the databases or maintain
the search tools locally.  Each time the Batch Client is used, it
queries the BCM Search Launcher for the most up-to-date list of search
tools.
	The Search Launcher Batch Client v. 2.5 is available from a link (A
Batch Client...) on the BCM Search Launcher home page.  The BCM Search
Launcher (http://gc.bcm.tmc.edu:8088/search-launcher/launcher.html) is
an enhanced, integrated, and easy-to-use interface that provides access
to a number of different web based sequence analysis services.  The
Search Launcher extends the functionality of other WWW services by
adding additional hypertext links which can be extremely helpful when
analyzing database search results.  

----------------------------------------------------------------
Kim C. Worley, Ph.D.      kworley@bcm.tmc.edu     P 713-798-8292	
Baylor College of Medicine, Houston, TX 77030     F 713-798-5386	
http://kiwi.imgen.bcm.tmc.edu:8088/search-launcher/launcher.html
----------------------------------------------------------------

From owner-software@net.bio.net Thu Apr 10 23:00:00 1997
Path: biosci!rutgers.rutgers.edu!gatech!csulb.edu!hammer.uoregon.edu!news-peer.gsl.net!news-peer.sprintlink.net!news.sprintlink.net!sprint!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!paladin.american.edu!news.ecn.uoknor.edu!munnari.OZ.AU!metro!metro!news
From: Phillip Robinson <phrobins@mail.usyd.edu.au>
Newsgroups: bionet.software
Subject: Re: alignment software
Date: Fri, 11 Apr 1997 17:15:23 +1000
Organization: Information Technology Services, The University of Sydney, NSW, Australia
Lines: 19
Distribution: inet
Message-ID: <334DE50B.25F4@mail.usyd.edu.au>
References: <5iic0h$39s$1@vishnu.jussieu.fr>
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Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0 (Win95; I)

Michel SEIGNEURET wrote:
> 
> Dear Collegues.
> My question is probably trivial but I am a newcomer to this field and
> I could not find a FAQ on this.
> I currently often do BLAST or FASTA searches of particular protein sequences
> against the SWISSPROT or PIR databases though the WWW. The problem is that the
> internet connection of my lab is slow. I am thus thinking of doing such
> searches locally after downloading the complete database. Could somebody
> suggest me a freely available software that allows one to do a BLAST or FASTA
> alignment search locally ?
> Thank you in advance.

I believe you need the PC-based Windows program AnTheProt.  Available
from: http://www.ibcp.fr:80/antheprot.html

At least, I use it and think it is magic.

Phil					Sydnay, Australia

From owner-software@net.bio.net Fri Apr 11 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.uth.tmc.edu!news.uh.edu!swrinde!howland.erols.net!europa.clark.net!news.maxwell.syr.edu!newsfeeder.toronto.ican.net!nnrp1.toronto.ican.net!newsfeeder
From: ppang@ican.net (Patrick Pang)
Newsgroups: bionet.software
Subject: Read non-English site with Netscape(3-4) & Internet Explorer(3-4) WITHOUT external viewer
Date: Fri, 11 Apr 1997 01:56:41 GMT
Organization: Patrick Cyber Domain µê¤Û»â°ì http://ppang.home.ml.org
Lines: 17
Message-ID: <33bf95c6.12775944@news.ican.net>
NNTP-Posting-Host: ppp-138.toronto-03.ican.net
Mime-Version: 1.0
Content-Type: text/plain; charset=ISO-8859-1
Content-Transfer-Encoding: 8bit
X-Newsreader: Forte Agent 1.0/32.390

Find out how to configure Chinese, Japanese, Korean & PanEuro
as well) viewing with Netscape(3.0-4.0 PR3) and Internet Explorer
(3.0-4.0 Beta1) under English Windows 95/NT WITHOUT external viewer.
Also, find out how to use IE4.0 Outlook Express & Netscape 4.0
Collabra/Messenger to read non-English mail/news.

http://ppang.home.ml.org

Besdies, the FREE section contains many Free Internet Resources
such as free counter, e-mail a/c, guestbook, web space and more.
 __________           __   
 \______   \_____   _/  |_  Find out how to setup Netscape & MSIE  
  |     ___/\__  \  \   __\ to display Chinese, Japanese, Korean &
  |    |     / __ \_ |  |   Pan Euro without external viewer in         
  |____|    (____  / |__|   Patrick Cyber Domain µê¤Û»â°ì, ½Ð¦h¦h«ü±Ð
                 \/      
Web Page: http://ppang.home.ml.org

From owner-software@net.bio.net Sat Apr 12 23:00:00 1997
Path: biosci!daresbury!uninett.no!nntp.uio.no!news.apfel.de!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news-peer.sprintlink.net!news.sprintlink.net!sprint!news.maxwell.syr.edu!news.visi.net!mur2.odyssey.on.ca!news3.sprint-canada.net!roger.interlynx.net!not-for-mail
From: Lars Thomsen <lthomsen@interlynx.net>
Newsgroups: bionet.software
Subject: Re: Patch clamp software
Date: Sat, 12 Apr 1997 14:23:54 -0700
Organization: Interlynx
Lines: 19
Message-ID: <334FFD6A.2F4C@interlynx.net>
References: <Pine.OSF.3.95.970408192410.24551B-100000@kokiux.koki.hu>
NNTP-Posting-Host: port144.hm.interlynx.net
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.0b2 (Win95; I)
X-Priority: 3 (Normal)

Get the whole cell version here :
http://physiology.cup.cam.ac.uk/Software/ftp.html

Im also working on some patch clamp analysis software and you can get it
at :
http://home.interlynx.net/~lthomsen/preader
Password for zipped file :
preader17

My program reads the Axon file format and needs Win95 and a screen
resolution of 800x600

--
Lars Thomsen, MSc PhD
115 South Oval, Hamilton, L8S1R2 Ontario, Canada
tlp +1 905 777 0720 fax +1 905 777 0738
email lthomsen@interlynx.net
homepage http://home.interlynx.net/~lthomsen


From owner-software@net.bio.net Sat Apr 12 23:00:00 1997
Path: biosci!roche.com!takeshi.komatani
From: takeshi.komatani@roche.com (Zicke Zacke)
Newsgroups: bionet.software
Subject: medline
Date: 13 Apr 1997 08:49:07 -0700
Organization: F.Hoffmann - La Roche Ltd
Lines: 10
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <334C9AE9.4560@roche.com>
Reply-To: takeshi.komatani@roche.com
NNTP-Posting-Host: net.bio.net

does anybody know how to import medline data from 
http://www4.ncbi.nlm.nih.gov/PubMed/


Thanks in advance
=======
KOMATANI, Takeshi $B6pC+9d;V(J
takeshi.komatani@roche.com
PhD candidate(Pharmaceutical Sciences)


From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!daresbury!uninett.no!nntp.uio.no!news.uoregon.edu!tezcat!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!news.maxwell.syr.edu!ott.istar!news.istar.net!tor.istar!east.istar!ftn.net!passport.ca!news
From: Ryan Burns <webmaster@fieldworker.com>
Newsgroups: bionet.agroforestry,bionet.plants,bionet.software,sci.bio.botany
Subject: Field Data Collection
Date: Mon, 14 Apr 1997 09:32:44 -0400
Organization: Fieldworker
Lines: 14
Message-ID: <335231FC.36AE@fieldworker.com>
Reply-To: webmaster@fieldworker.com
NNTP-Posting-Host: pm3-tor-05.passport.ca
Mime-Version: 1.0
Content-Type: text/plain; charset=iso-8859-1
Content-Transfer-Encoding: 8bit
X-Mailer: Mozilla 3.0Gold (Win95; I)
Xref: biosci bionet.agroforestry:5274 bionet.plants:15052 bionet.software:18338 sci.bio.botany:4467

FieldWorker is data collection software which runs on a handheld
computer.  We now support UTM coordinates for your field data
collection, in addition to latitude and longitude from GPS receivers 
Export collected data into any desktop mapping or GIS package.  Need
more info on this portable affordable solution?  FieldWorker’s website
now features an interactive online demo at http://www.fieldworker.com/
-- 
====================================================================
Ryan Burns, Webmaster                <webmaster@fieldworker.com>
Download FieldWorker 2.3 Demo!..at http://www.fieldworker.com
Navigation, Differential GPS, Offset, Relational Map, Multi-lingual!
   FieldWorker    -    Handheld PC data collection linked to GPS
-- FieldWorker Products Ltd.--               Tel: +1 416 483 3485
====================================================================

From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!gatech!smash.gatech.edu!news
From: Jing Li <jl98@prism.gatech.edu>
Newsgroups: bionet.software
Subject: Postscript file
Date: Mon, 14 Apr 1997 18:10:12 -0400
Organization: Georgia Institute of Technology
Lines: 11
Message-ID: <3352AB44.67E7@prism.gatech.edu>
NNTP-Posting-Host: acmex.gatech.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (Win95; I)

Is any one can tell me what program to use for creating a postscript
file so that the postscript file can be printed out on any postscript
printer, and no just the specified printer.  The reason is that I need
to put the postscript file onto my home page in the world wide web so
that others can download it and print it.

	Thank you very much.

Jing Li

mailto:jl98@prism.gatech.edu

From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!gatech!smash.gatech.edu!news
From: Jing Li <jl98@prism.gatech.edu>
Newsgroups: bionet.software
Subject: Postscript file
Date: Mon, 14 Apr 1997 18:07:57 -0400
Organization: Georgia Institute of Technology
Lines: 13
Message-ID: <3352AABD.5F0@prism.gatech.edu>
NNTP-Posting-Host: acmex.gatech.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (Win95; I)

Dear Friends:

	Is any one can tell me what program to use for creating a postscript
file so that the postscript file can be printed out on any postscript
printer, and no just the specified printer.  The reason is that I need
to put the postscript file onto my home page in the world wide web so
that others can download it and print it.

	Thank you very much.

Jing Li

mailto: jl98@prism.gatech.edu

From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!news.bbnplanet.com!nih.gov!usenet
From: bernard@elsie.nci.nih.gov (Bernard Murray)
Newsgroups: bionet.software
Subject: Re: Free practical programs for molecular biologists !!!
Date: 14 Apr 1997 20:43:50 GMT
Organization: National Institutes of Health, Bethesda, MD
Lines: 17
Message-ID: <5iu4u6$ib4@light.nih.gov>
References: <3351ECE2.44DA@vetvir.unizh.ch>
NNTP-Posting-Host: ermintrude.nci.nih.gov
X-Newsreader: WinVN 0.99.7

In article <3351ECE2.44DA@vetvir.unizh.ch>, rolfk@vetvir.unizh.ch says...
>
>I wrote a few practical and simple to use programs
[snip]

Rolf, I think you have a problem with your news submission
software as I am receiving this message at least once a week
and I doubt if you are updating your software so frequently
(actually I'm not personally interested in it).
	Could you make the necessary change(s) to cut down on
the traffic?
	Much appreciated,
		Bernard

Bernard Murray, Ph.D.
bernard@elsie.nci.nih.gov (National Cancer Institute, NIH, Bethesda MD, USA)


From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.maxwell.syr.edu!news.magicnet.net!magicnet.magicnet.net!pmod
From: pmod@magicnet.net (Peter M. O'Donnell)
Newsgroups: bionet.software.gcg,bionet.software,comp.sys.sun.wanted,comp.sys.sun.hardware
Subject: Re: Solaris 2.x on a Pentium?
Followup-To: bionet.software.gcg,bionet.software,comp.sys.sun.wanted,comp.sys.sun.hardware
Date: 14 Apr 1997 21:07:09 GMT
Organization: MagicNet, Inc.
Lines: 24
Distribution: world
Message-ID: <5iu69t$403$1@comet3.magicnet.net>
References: <Pine.LNX.3.94.970413152130.7642A-100000@ktb2.ktb.net>
NNTP-Posting-Host: magicnet.magicnet.net
X-Newsreader: TIN [version 1.2 PL2]
Xref: biosci bionet.software.gcg:2360 bionet.software:18345 comp.sys.sun.wanted:19891 comp.sys.sun.hardware:46096

Albert Gold (bgold@ktb.net) wrote:

: I know that SUN apparently makes an OS which clearly will run
: upon Pentium machines, called X86, but that system is
: NOT Solaris.

	nope. it is indeed solaris. there is solaris for the sparc family,
and there is solaris for the x86 (intels).

: Has anybody tried running Solaris on a Pentium machine?  Does it work?

	it absolutely does, and work very very well. bang the search
engines to get a clue^H^H^H^Hfaq.

[silly glossary chopped]

	uh, a lot of that was either wrong, or misleading. like i said,
check out the faqs.

--
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
  Peter M. O'Donnell   }    pmod@magicnet.net    { "If you are going to 
  A.U. Student,CNA,MCP {      pmod@abs.net       } walk on thin ice, you
  "Clickity-Clickity"  }   po0115a@american.edu  { might as well dance!" 

From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!agate!dog.ee.lbl.gov!overload.lbl.gov!news.emf.net!gatech!smash.gatech.edu!news
From: Jing Li <jl98@prism.gatech.edu>
Newsgroups: bionet.software,comp.ai,comp.groupware,comp.infosystems,comp.misc
Subject: Postscript file:  help me please!!!
Date: Mon, 14 Apr 1997 18:21:57 -0400
Organization: Georgia Institute of Technology
Lines: 10
Message-ID: <3352AE05.1DA9@prism.gatech.edu>
NNTP-Posting-Host: acmex.gatech.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (Win95; I)
Xref: biosci bionet.software:18349 comp.ai:30411 comp.groupware:8000 comp.infosystems:8578 comp.misc:29018

Is any one can tell me how to create a postscript file so that the file
can be printed out on any postscript printer, and no just a specified
printer.  The reason is that I need to put some documents onto my home
page in the world wide web so that others can download it and print it.

	Thank you very much.

Jing Li

mailto:jl98@prism.gatech.edu

From owner-software@net.bio.net Sun Apr 13 23:00:00 1997
Path: biosci!biosci!not-for-mail
From: Albert Gold <bgold@ktb.net>
Newsgroups: bionet.software.gcg,bionet.software,comp.sys.sun.wanted,comp.sys.sun.hardware
Subject: Solaris 2.x on a Pentium?
Date: 14 Apr 1997 12:48:36 -0700
Organization: KTB Internet Online
Lines: 45
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <Pine.LNX.3.94.970413152130.7642A-100000@ktb2.ktb.net>
Reply-To: Albert Gold <bgold@ktb.net>
NNTP-Posting-Host: net.bio.net
Xref: biosci bionet.software.gcg:2358 bionet.software:18342 comp.sys.sun.wanted:19890 comp.sys.sun.hardware:46095


Readers of this note probably know that GCG's Wisconsin Package is
supported by only a limited number of Operating Systems.  None of these
to my knowledge runs on an inexpensive Pentium or Power-Mac. machine.

Reading the back of one of the 'Partition Magic' -like software boxes
today (boot level OS option), I came upon the word 'Solaris' as an
OS possibility.  

I know that SUN apparently makes an OS which clearly will run
upon Pentium machines, called X86, but that system is
NOT Solaris.

I know from taking these newsgroups seriously that SunOS was originally
based upon BSD, but apparently 'Solaris' departed from this initiative
and moved to incorporate several DEC Fortran extensions, which GCG
relies upon.  Solaris 2.3 and 2.4 are supportable GCG Operating Systems.

Has anybody tried running Solaris on a Pentium machine?  Does it work?

[Short Glossary]

GCG= Genetics Computer Group
Sun= Sun Microsystems Inc.
DEC= Digital Equipment Corporation
Solaris= Unix operating system incorporating C shells, Korn Shells and
         Bourne shells with old Berkeley Unix (with AT&T Bell Labs)
         specifically designed? for Sun Microsystem computers.
OS or OSs= Operating Systems
BSD= Berkeley Software Design, a form of unix of which one is apparently
     free and available for downloading all over the net, commonly called
     Free BSD, and one is costly and available from Berkeley Software
     Design Incorporated of Colorado (1-800-800-BSDI).
X86= A form of Unix sold by Sun Microsystems which apparently runs
     on Pentium machines.
SunOS= An early form of the Sun Microsystems Operating System which
       was based on the unix designed by authors at U. Cal. at Berkeley
       and those 