From owner-software@net.bio.net Sun Feb 01 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news-peer.gip.net!news-lond.gip.net!news.gsl.net!gip.net!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail
From: ctzhang@tju.edu.cn (chun ting zhang)
Newsgroups: bionet.software
Subject: software to print protein structure images
Date: 2 Feb 1998 16:48:47 -0000
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Dear netters:

By what software (for PC) I can use to print out high quality 
protein images, for example, ribbons or cartoons. 
Thank you very much in advance.

R. Zhang

E-mail address: ctzhang@tju.edu.cn


From owner-software@net.bio.net Sun Feb 01 22:00:00 1998
From: brais@gte.net
To: brais@gte.net
Subject: Corrupted Data files
Date: Sun, 01 Feb 1998 23:01:43 -0600
Reply-To: braispa2@mail.northgrum.com
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In opening word perfect 6.1 for windows files I get a bunch of garbage
characters. After attempting to recover from backup I get the error that
says that the header is corrupted. What I would like to know if anyone
has had any experience with retrieving information under similar
circumstances. I have probably 100 files and none of them are readable.
Is there a utility available which can read and repair the header
information? Thanks in advance for any information or help.

-------------------==== Posted via Deja News ====-----------------------
      http://www.dejanews.com/     Search, Read, Post to Usenet

From owner-software@net.bio.net Sun Feb 01 22:00:00 1998
Path: biosci!bloom-beacon.mit.edu!news.kodak.com!news-pen-16.sprintlink.net!newsfeed.nysernet.net!news.nysernet.net!207.41.200.14!news-pen-14.sprintlink.net!206.229.87.26!news-east.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.nacamar.de!fu-berlin.de!news-ber1.dfn.de!news-ham1.dfn.de!news.mu-luebeck.de!not-for-mail
From: "Lars Komorowski" <larskomo@physik.mu-luebeck.de>
Newsgroups: bionet.software
Subject: HPLC-Manager-Software
Date: Mon, 2 Feb 1998 20:49:42 +0100
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Who can help me ? I lost data from HPLCManager 3.0 for DOS from Pharmacia
LKB. And I don't have the disks anymore (they were from 1991). Who can send
me the installation files or maybe newer ones if they work ?
Lars



From owner-software@net.bio.net Sun Feb 01 22:00:00 1998
Path: biosci!agate!newsfeed.kornet.nm.kr!nntp.kreonet.re.kr!fnews.nuri.net!news.nuri.net!not-for-mail
From: Tae-Young Ahn <tyahn@nuri.net>
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: Tue, 03 Feb 1998 08:36:03 +0900
Organization: A-Lab, CNS, Seoul, Korea
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To: chun ting zhang <ctzhang@tju.edu.cn>
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chun ting zhang wrote:

> Dear netters:
>
> By what software (for PC) I can use to print out high quality
> protein images, for example, ribbons or cartoons.
> Thank you very much in advance.
>
> R. Zhang
>
> E-mail address: ctzhang@tju.edu.cn

Try RasMol.

You can get  freeware at http://www.umass.edu/microbio/rasmol/getras.htm

======================================================

Tae-Young

"We all agree that your theory is crazy. The question which divides us
is whether it is crazy enough." -- Niels Bohr



From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Message-ID: <34D6D8BE.BE7451B@medgen.uu.se>
Date: Tue, 03 Feb 1998 09:43:42 +0100
From: Martti Tammi <marttit@medgen.uu.se>
Organization: University of Uppsala, Dept of Genetics and Pathology, Medical Genetics Unit
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James Yegerlehner wrote:

> Hello-
> Can anyone point me to a directory of bioinformatics programs of study and
> their universities?
>
> Thanks in advance,
> Jim

Since you didn't specify the type of programs you are looking for I suggest
you begin with the following:
http://www.genet.sickkids.on.ca/bioinfo_resources/software.html

other links for bioinformatics and biocomputing courses:
http://www.techfak.uni-bielefeld.de/techfak/persons/chrisb/biocourse/
http://biotech.chem.indiana.edu/pages/bioinform/biprograms_us.html
http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/syllabi.html
http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/MulAli/welcome.html
http://www.ebi.ac.uk/ebi_home.html
http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/FDSear/welcome.html
http://genome.imb-jena.de/learning.html
http://www.vsms.nottingham.ac.uk/vsms/index.html
http://www.cs.sandia.gov/~scistra/course
http://cmgm.stanford.edu/biochem218/
http://www.hgmp.mrc.ac.uk/Public/Docs/Courses/index.html
http://www.cs.jhu.edu/~salzberg/cs439.html

-martti tammi PhD stud
bioinformatics


--
Martti Tammi                            UPPSALA UNIVERSITY
Bandstolsvaegen 20                      Biomedical Center
S-756 46  UPPSALA                       Department of Genetics and Pathology
Home: +46 18  30 31 13                  Unit of Medical Genetics, BOX 589
BMC:  +46 18  471 4107                  S-751 24 UPPSALA, Sweden
Fax   +46 18  52 68 49                  http://www.medgen.uu.se



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<HTML>
James Yegerlehner wrote:
<BLOCKQUOTE TYPE=CITE>Hello-
<BR>Can anyone point me to a directory of bioinformatics programs of study
and
<BR>their universities?

<P>Thanks in advance,
<BR>Jim</BLOCKQUOTE>
Since you didn't specify the type of programs you are looking for I suggest
you begin with the following:
<BR><A HREF="http://www.genet.sickkids.on.ca/bioinfo_resources/software.html">http://www.genet.sickkids.on.ca/bioinfo_resources/software.html</A>

<P>other links for bioinformatics and biocomputing courses:
<BR><A HREF="http://www.techfak.uni-bielefeld.de/techfak/persons/chrisb/biocourse/">http://www.techfak.uni-bielefeld.de/techfak/persons/chrisb/biocourse/</A>
<BR><A HREF="http://biotech.chem.indiana.edu/pages/bioinform/biprograms_us.html">http://biotech.chem.indiana.edu/pages/bioinform/biprograms_us.html</A>
<BR><A HREF="http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/syllabi.html">http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/syllabi.html</A>
<BR><A HREF="http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/MulAli/welcome.html">http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/MulAli/welcome.html</A>
<BR><A HREF="http://www.ebi.ac.uk/ebi_home.html">http://www.ebi.ac.uk/ebi_home.html</A>
<BR><A HREF="http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/FDSear/welcome.html">http://merlin.mbcr.bcm.tmc.edu:8001/bcd/Curric/FDSear/welcome.html</A>
<BR><A HREF="http://genome.imb-jena.de/learning.html">http://genome.imb-jena.de/learning.html</A>
<BR><A HREF="http://www.vsms.nottingham.ac.uk/vsms/index.html">http://www.vsms.nottingham.ac.uk/vsms/index.html</A>
<BR><A HREF="http://www.cs.sandia.gov/~scistra/course">http://www.cs.sandia.gov/~scistra/course</A>
<BR><A HREF="http://cmgm.stanford.edu/biochem218/">http://cmgm.stanford.edu/biochem218/</A>
<BR><A HREF="http://www.hgmp.mrc.ac.uk/Public/Docs/Courses/index.html">http://www.hgmp.mrc.ac.uk/Public/Docs/Courses/index.html</A>
<BR><A HREF="http://www.cs.jhu.edu/~salzberg/cs439.html">http://www.cs.jhu.edu/~salzberg/cs439.html</A>

<P>-martti tammi PhD stud
<BR>bioinformatics
<BR>&nbsp;
<PRE>--&nbsp;
Martti Tammi&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; UPPSALA UNIVERSITY&nbsp;
Bandstolsvaegen 20&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Biomedical Center
S-756 46&nbsp; UPPSALA&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Department of Genetics and Pathology
Home: +46 18&nbsp; 30 31 13&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Unit of Medical Genetics, BOX 589
BMC:&nbsp; +46 18&nbsp; 471 4107&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; S-751 24 UPPSALA, Sweden
Fax&nbsp;&nbsp; +46 18&nbsp; 52 68 49&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <A HREF="http://www.medgen.uu.se">http://www.medgen.uu.se</A></PRE>
&nbsp;</HTML>

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From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Message-ID: <34D6D993.44941FCC@medgen.uu.se>
Date: Tue, 03 Feb 1998 09:47:16 +0100
From: Martti Tammi <marttit@medgen.uu.se>
Organization: University of Uppsala, Dept of Genetics and Pathology, Medical Genetics Unit
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James Yegerlehner wrote:

> Hello-
> Can anyone point me to a directory of bioinformatics programs of study and
> their universities?
>
> Thanks in advance,
> Jim

A linux site:
http://www-ocean.tamu.edu/~baum/linuxlist-a.html


--
Martti Tammi                            UPPSALA UNIVERSITY
Bandstolsvaegen 20                      Biomedical Center
S-756 46  UPPSALA                       Department of Genetics and Pathology
Home: +46 18  30 31 13                  Unit of Medical Genetics, BOX 589
BMC:  +46 18  471 4107                  S-751 24 UPPSALA, Sweden
Fax   +46 18  52 68 49                  http://www.medgen.uu.se



--------------F1AE668CDDB14B1A112CE64F
Content-Type: text/html; charset=us-ascii
Content-Transfer-Encoding: 7bit

<HTML>
James Yegerlehner wrote:
<BLOCKQUOTE TYPE=CITE>Hello-
<BR>Can anyone point me to a directory of bioinformatics programs of study
and
<BR>their universities?

<P>Thanks in advance,
<BR>Jim</BLOCKQUOTE>
A linux site:
<BR><A HREF="http://www-ocean.tamu.edu/~baum/linuxlist-a.html">http://www-ocean.tamu.edu/~baum/linuxlist-a.html</A>
<BR>&nbsp;
<PRE>--&nbsp;
Martti Tammi&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; UPPSALA UNIVERSITY&nbsp;
Bandstolsvaegen 20&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Biomedical Center
S-756 46&nbsp; UPPSALA&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Department of Genetics and Pathology
Home: +46 18&nbsp; 30 31 13&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Unit of Medical Genetics, BOX 589
BMC:&nbsp; +46 18&nbsp; 471 4107&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; S-751 24 UPPSALA, Sweden
Fax&nbsp;&nbsp; +46 18&nbsp; 52 68 49&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <A HREF="http://www.medgen.uu.se">http://www.medgen.uu.se</A></PRE>
&nbsp;</HTML>

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From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!agate!howland.erols.net!feed1.news.erols.com!feed2.news.erols.com!news1.best.com!nntp1.ba.best.com!shell7.ba.best.com!jquinn
From: Greg <jquinn@shell7.ba.best.com>
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: 3 Feb 1998 04:40:12 GMT
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chun ting zhang <ctzhang@tju.edu.cn> wrote:
> Dear netters:

> By what software (for PC) I can use to print out high quality 
> protein images, for example, ribbons or cartoons. 
> Thank you very much in advance.

Per Kraulis has written a very good program called Molscript which is able to ouput
high quality cartoons of proteins. You need to sign a license to get it, but there is
(I think still) no charge. Raster3d is an excellent set of programs which output high
quality images. Both Molscript  and Raster3d are command line programs and have been
compiled for the PC by various people. Rasmol, also available for the PC, is of
course also able to output ribbon and cartoon images but the last time I checked,
these were not really of publication quality (someone please correct me if I am
wrong).

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!agate!howland.erols.net!EU.net!newsfeed.Austria.EU.net!Austria.EU.net!not-for-mail
From: Gerald Loeffler <loeffler@bender.co.at>
Newsgroups: bionet.software
Subject: Re: Data Analysis
Date: Tue, 03 Feb 1998 13:35:12 +0100
Organization: Boehringer Ingelheim Vienna (Bender Wien)
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Hi!

I'm currently in the process of getting my company to buy such a piece
of software. I got the impression that S-PLUS my Mathsoft is being used
by several people with success. A look at the web-page certainly looked
encouraging, and so I decided to opt for S-PLUS.

The strength of S-PLUS seems to be in exploratory data analysis and
statistical functions. By exploratory I (or rather mathsoft!!!) mean the
quick, interactive looking at various aspects of a large,
multi-dimensional data-set to discover patterns. This aspect is
important for me and also seems to be what Alan needs.

Here in Austria, the price would be a bit less than $3000 for a Win32
version. A lot, but acceptable.

	cheers,
	gerald



Alan J. Robinson wrote:
> 
> I would like to be able to do relatively simple manipulation and
> analysis of data sets, along the lines of the basic capabilities of
> SAS.  As you may know, statistics packages like SAS, (and ESPECIALLY
> SAS) are VERY expensive.  Are there other tools out there in the UNIX
> and Windows95 world which will do pretty much the same thing?  (I've
> found spread sheets to be rather clumsy for this sort of thing.)
> 
> (What I have in mind is doing data exploration on the output of the DSSP
> program for PDB protein structures.)
> 
> Alan J. Robinson
> robin073@tc.umn.edu

-- 
Gerald Loeffler - Bioinformaticist
Boehringer Ingelheim Vienna (aka: Bender Wien)
Email: loeffler@bender.co.at
Phone: +43 1 80105 338 and +43 676 3289588
Fax:   +43 1 8041540
Smail: Dr. Boehringer-Gasse 5-11, A-1121 Vienna, Austria

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!agate!howland.erols.net!news.maxwell.syr.edu!news-ge.switch.ch!surfnet.nl!ruu.nl!gillies
From: Malcolm Gillies <M.B.Gillies@far.ruu.nl>
Newsgroups: bionet.software
Subject: Re: Data Analysis
Date: 3 Feb 1998 13:09:13 GMT
Organization: Utrecht University, The Netherlands
Lines: 41
Message-ID: <6b74tp$anq$1@news.cc.ruu.nl>
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NNTP-Posting-Host: cmcind.far.ruu.nl
Originator: gillies@cmcind

>Alan J. Robinson wrote:
>> I would like to be able to do relatively simple manipulation and
>> analysis of data sets, along the lines of the basic capabilities of
>> SAS.  As you may know, statistics packages like SAS, (and ESPECIALLY
>> SAS) are VERY expensive.  Are there other tools out there in the UNIX
>> and Windows95 world which will do pretty much the same thing?  (I've
>> found spread sheets to be rather clumsy for this sort of thing.)

In article <34D70F00.DB4@bender.co.at>,
Gerald Loeffler  <loeffler@bender.co.at> wrote:
>I'm currently in the process of getting my company to buy such a piece
>of software. I got the impression that S-PLUS my Mathsoft is being used
>by several people with success. A look at the web-page certainly looked
>encouraging, and so I decided to opt for S-PLUS.

I've had some success with the "R" package, which implements a language
very close to "S", as used in S-Plus (it's close enough that I managed
to port an S-plus extension written in F77 from the Statlib S Archive
without any problems, but I may have just been lucky).

R is free under the Gnu Public License. The current release is 0.61.1,
but I've found it to be reasonably complete and stable.

See:

The R Home Page

    http://www.stat.auckland.ac.nz/r/r.html

R FAQ

    http://www.ci.tuwien.ac.at/~hornik/R/R-FAQ.html

cheers,

Malcolm
--
Malcolm Gillies <M.B.Gillies@far.ruu.nl>
PhD Student, computational medicinal chemistry
Dept Medicinal Chemistry, Faculty of Pharmacy
Utrecht University, The Netherlands

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!sanbi.ac.za!andrey
From: andrey@sanbi.ac.za (Andrey A Ptitsyn)
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: 3 Feb 1998 03:04:52 -0800
Organization: SANBI
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NNTP-Posting-Host: net.bio.net

Try WPDB from San Diego Supercomputer Center,

http://www.sdsd.edu/CCMS/Packages/Wpdb.html

chun ting zhang wrote:
> 
> Dear netters:
> 
> By what software (for PC) I can use to print out high quality
> protein images, for example, ribbons or cartoons.
> Thank you very much in advance.
> 
> R. Zhang
> 
> E-mail address: ctzhang@tju.edu.cn

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!bloom-beacon.mit.edu!news.kodak.com!news-pen-16.sprintlink.net!newsfeed.nysernet.net!news.nysernet.net!207.41.200.14!news-pen-14.sprintlink.net!206.229.87.26!news-east.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!europa.clark.net!194.159.255.21!dispose.news.demon.net!demon!news.demon.co.uk!demon!mail2news.demon.co.uk!pdchem.demon.co.uk!Paul
From: Paul@pdchem.demon.co.uk (Paul Davis)
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: Tue, 03 Feb 98 09:54:57 GMT
Organization: Myorganisation
Distribution: bionet
Message-ID: <886499697snz@pdchem.demon.co.uk>
References: <6b4tdf$k79@mserv1.dl.ac.uk> <6b673c$k4g$1@nntp1.ba.best.com>
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In article <6b673c$k4g$1@nntp1.ba.best.com>
           jquinn@shell7.ba.best.com "Greg" writes:

> 
> Per Kraulis has written a very good program called Molscript which is able to
>  ouput
> high quality cartoons of proteins. You need to sign a license to get it, but
>  there is
> (I think still) no charge.

Also see the following article:-

Robert M. Esnouf (1997). "An extensively modified version of MolScript
that includes greatly enhanced coloring capabilities". Journal of Molecular
Graphics and Modelling vol 15 p132-134.

-Paul

-- 

--------------------------------------------------------------------
Paul Davis                                   paul@pdchem.demon.co.uk


From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Sender: thomas@evolution.bmc.uu.se
To: "James Yegerlehner" <yeger@completebbs.com>
Newsgroups: bionet.software
Subject: Re: bioinformatics?
References: <6b2n9v$87p$1@spk-news1.nwnexus.com>
From: Thomas Sicheritz <Thomas.Sicheritz@molbio.uu.se>
Date: 03 Feb 1998 10:39:27 +0100
Message-ID: <x6ra5lvxgw.fsf@evolution.bmc.uu.se>
Lines: 27
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"James Yegerlehner" <yeger@completebbs.com> writes:

> Hello-
> Can anyone point me to a directory of bioinformatics programs of study and
> their universities?
> 
> Thanks in advance,
> Jim

Undergraduate and graduate courses at Uppsala University
http://evolution.bmc.uu.se/~siv/gnomics/courses.html

Courses at George Mason University
http://www.science.gmu.edu/~michaels/Bioinformatics/#p1

-thomas

-- 
Sicheritz Ponten Thomas E.  Department of Molecular Biology
Biomedical Center           Uppsala University
BMC:  +46 18 4714214        BOX 590 S-751 24 UPPSALA Sweden
Fax   +46 18  557723        http://evolution.bmc.uu.se/~thomas
Molecular Tcl:   http://evolution.bmc.uu.se/~thomas/tcl
Molecular Linux: http://evolution.bmc.uu.se/~thomas/mol_linux
 
	De Chelonian Mobile ... The Turtle Moves ...


From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
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From: "Joseph James" <qtechsof@ix.netcom.com>
Newsgroups: bionet.software
Subject: Software Engineering
Date: Tue, 3 Feb 1998 16:12:29 -0500
Organization: Netcom
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I am a semi-retired software engineer and technical writer with thirty
years of professional experience, most of it acquired through the
development of complex applications for scientists and mathematicians
involved in research, as well as for Fortune 500 corporations in the
United States.  During the last decade, I've created custom software
for an international clientele as an internet-based developer.  I
specialize in the rapid, cost-effective prototyping of scientific and
mathematical applications (for both small-circle research use and for
commercial deployment), and I only work on one project at a time.
I do not have a website and do no advertising other than occasional
newsgroup messages like this one.

If you have a serious interest in developing a prototype of a
software system which meets the abovementioned criteria, please
feel free to contact me by email using the address below for a free
consultation, without any cost or obligation whatsoever.  If your
application interests me sufficiently, I will prototype it free of
charge in exchange for your willingness to provide an honest
business reference and appraisal of my work to other potential
clients, upon request.

Joseph James

qtechsofXXX-AT-XXXix.netcom.com (SPAM GUARD: replace the
                                 characters "XXX-AT-XXX"
                                 with the character "@"
                                 to obtain my actual
                                 email address.)



From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!agate!newsfeed.kornet.nm.kr!howland.erols.net!news.maxwell.syr.edu!news.cis.ohio-state.edu!magnus.acs.ohio-state.edu!rrumpf
From: rrumpf@postbox.acs.ohio-state.edu (Dr. Robert Rumpf)
Newsgroups: bionet.software
Subject: Alpha Innotech ProScan RFLP software - Opinions?
Date: Tue, 03 Feb 1998 13:44:46 -0500
Organization: The Ohio State University Dept. of Oral Biology
Lines: 14
Message-ID: <rrumpf-0302981344460001@128.146.74.139>
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X-Newsreader: MT-NewsWatcher 2.3.5

We're looking for some good software that will analyze band patterns from
multiple reactions and establish a profile database which can then be
searched for pattern matches.  We've seen literature on the Alpha Innotech
ProScan stuff and were wondering what the net opinion was.  Is there
anything better out there?  We can use PC or Mac but prefer Mac by far...

************************************************************************ 
* Dr. Robert Rumpf - rumpf.1@osu.edu - http://www.marcon.org/users/bob *
*                                                                      *
*       It is by caffeine alone that I set my mind in motion           *
*       By the beans of java, my thoughts acquire speed                *
*       The hands acquire the shakes, the shakes become a warning      *
*       It is by caffeine alone that I set my mind in motion           *
************************************************************************ 

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
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From: "George Liakopoulos" <karab@auadec.aua.ariadne-t.gr>
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: Tue, 3 Feb 1998 20:32:39 +0200
Organization: Lab of Plant Physiology
Lines: 16
Message-ID: <6b7o0c$pma$1@ulysses.noc.ntua.gr>
References: <6b4tdf$k79@mserv1.dl.ac.uk>
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Hi,
Try the WEBLAB VIEWER. ITS GOOD!!!
The address: http://www.msi.com/weblab/viewer
Then, you have to provide the program with protein sequencies. Try the
following for start:
http://expasy.hcuge.ch/
I hope this helps.
George Liakopoulos
Post graduate student
Lab of Plant Physiology
Agricultural University of Athens
HELLAS
email: karab@auadec.aua.ariadne-t.gr




From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
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From: "Gaëtan MERCENIER" <gaetan.mercenier@ping.be>
Newsgroups: bionet.software
Subject: Hosting for Softwares...
Date: Tue, 3 Feb 1998 17:04:36 +0100
Organization: EUnet Belgium, Leuven, Belgium
Lines: 8
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Hello !

I can host your softwares at competitive rates. If you are interested:
webmaster@gate2net.com .

(Including sub-domains or domain names)



From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Path: biosci!agate!howland.erols.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news.mindspring.net!cssun.mathcs.emory.edu!cronkite.cc.uga.edu!twopaths
From: russell@dogwood.botany.uga.edu (Russell Malmberg)
Newsgroups: bionet.software
Subject: announce Peaks software to analyze HPLC data
Date: Tue, 03 Feb 1998 13:34:33 GMT
Organization: Botany Department, University of Georgia
Lines: 60
Message-ID: <6b76b2$s0e$1@cronkite.cc.uga.edu>
NNTP-Posting-Host: twopaths.botany.uga.edu
Keywords: software, HPLC, integrate, Windows NT
X-Newsreader: News Xpress 2.01

Peaks Software availability:
http://www.botany.uga.edu/malmberg/software.html

Peaks is a utility to analyze data from an HPLC or similar instrument.

Peaks was written to analyze data from our laboratory HPLC which
consisted of a time axis, and a y-axis, where we wished to integrate
areas under the various peaks in our data.  This data typically comes
from laboratory instruments that are connected by an Analog to Digital
card to a computer.
The current version of Peaks is fully windowed, and includes both text
and graphical output.
Peaks is a 32 bit program for Windows NT or Windows 95.  Versions are
available for Intel and for DEC alpha processors.

A major advantage of Peaks is that it is free.

This is the product of my first serious C++ programming exercise.  I
wrote it to learn C++ and windows programming, and because my
laboratory colleagues needed such a program.  Peaks fills a need we
had, and I’m distributing it in the hopes it is useful to others. It
probably has bugs and various unanticipated methods of crashing (use at
your own risk), but it seems to work.  Please send me an e-mail if you
find it useful, or when you find a bug.

A few other biology programs for Windows NT are available at my web
site. These are typically programs that someone else wrote, and they
were gracious enough to allow me to compile them for windows NT.
These include:

        ClustalW for a DEC Alpha.
        ClustalX for a DEC Alpha.
        GeneDoc 2.2 for a DEC Alpha.
        MapMaker and QTL for a DEC Alpha.
        Molphy 2.2 (Protml) for a DEC Alpha.
        NCBI programs Nentrez, Blast client, Sequin for a DEC Alpha.
        Peaks 0.8 for a DEC Alpha.
        Phylip 3.57 for a DEC Alpha.
        ReadSeq for a DEC Alpha.
        SeqPup 0.5 for a DEC Alpha.
        -----------------------------
        MapMaker and QTL for an Intel.
        Molphy 2.2 (Protml) for an Intel.
        Peaks 0.8 for an Intel.

Note that DEC alpha binaries will not run on an Intel CPU computer.

Russell L. Malmberg
Botany Department
University of Georgia
Athens, GA 30602-7271

e-mail. russell@dogwood.botany.uga.edu 
web page. http://www.botany.uga.edu/malmberg/


-----
 Russell L. Malmberg
 russell@dogwood.botany.uga.edu
 http://dogwood.botany.uga.edu/malmberg/

From owner-software@net.bio.net Mon Feb 02 22:00:00 1998
Date: Tue, 03 Feb 1998 12:34:29 +0100
From: zjons@vetbio.unizh.ch (Zophonias O. Jonsson)
Newsgroups: bionet.software
Distribution: bionet
Subject: Re: software to print protein structure images
Message-ID: <zjons-0302981234290001@130.60.120.27>
References: <6b4tdf$k79@mserv1.dl.ac.uk>
Organization: Universitat Zurich-Irchel
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In article <6b4tdf$k79@mserv1.dl.ac.uk>, ctzhang@tju.edu.cn (chun ting
zhang) wrote:

> Dear netters:
> 
> By what software (for PC) I can use to print out high quality 
> protein images, for example, ribbons or cartoons. 
> Thank you very much in advance.
> 
> R. Zhang
> 
> E-mail address: ctzhang@tju.edu.cn

My personal favourit is the Swiss-PdbViewer available freely at 

http://www.expasy.ch/spdbv/mainpage.htm

I have tried both the Mac and PC versions (2.6) and both of them do a very
decent job (either on a Power Mac 8600/200 or a P166 PC).  You will need
the QuickDraw3D library from apple to run the program, but that is
available for free, and if you want to generate really nice ray traced
images you can export the scenes that you generate to POV-ray (a freeware
rendering program).

My compliments to Nicolas Guex and Manuel C. Peitsch for an excellent program!

Zophonias

_____________________________________________________________________
Zophonias O. Jonsson
Institut fur Veterinarbiochemie               Tel: (41-1)-635-54-75
Universitat Zurich-Irchel                     Fax: (41-1)-635-68-16
Winterthurerstrasse 190
CH-8057 Zurich
Switzerland
_____________________________________________________________________

From owner-software@net.bio.net Tue Feb 03 22:00:00 1998
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From: "Michael W. Thompson" <nospam@nospam.noway.nohow>
Newsgroups: bionet.software
Subject: Re: Corrupted Data files
Date: Wed, 04 Feb 1998 16:07:09 -0500
Organization: CampusMCI
Lines: 29
Message-ID: <34D8D87D.5F96FD46@nospam.noway.nohow>
References: <886395353.1341128719@dejanews.com>
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brais@gte.net wrote:

> In opening word perfect 6.1 for windows files I get a bunch of garbage
> characters. After attempting to recover from backup I get the error that
> says that the header is corrupted. What I would like to know if anyone
> has had any experience with retrieving information under similar
> circumstances. I have probably 100 files and none of them are readable.
> Is there a utility available which can read and repair the header
> information? Thanks in advance for any information or help.

    Sounds like you might have a word "macro virus"-- we had one on our lab
computer that caused some similar symptoms.  An up-to-date virus checker
(you can find those at download.com or any similar site) will take care of
the problem, if that is indeed the problem.  Hope that helps.
replies-- post here.  I refuse to post my real email address here due to the
deluge of SPAM that it causes.
--
Michael W. Thompson
Univ. of Kentucky, Dept. of Biochemistry

Western Kentucky Photo Gallery:
     http://sac.uky.edu/~mthom0/sitemap.htm

Wildflowers of Western Kentucky:
     http://sac.uky.edu/~mthom0/flora.htm



From owner-software@net.bio.net Tue Feb 03 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!ais.net!vixen.cso.uiuc.edu!news.indiana.edu!news.iupui.edu!not-for-mail
From: "Charlie Mantel" <cmante@topaz.iupui.edu>
Newsgroups: bionet.software
Subject: Re: Dot blot analyzer
Date: Tue, 3 Feb 1998 23:28:55 -0500
Organization: Indiana University - Purdue Univeristy At Indianapols,IN
Lines: 11
Message-ID: <6b8rug$mrp$1@hercules.iupui.edu>
References: <34D1FCB5.768A@ipst.edu>
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Try these links::
http://facs.scripps.edu/
http://facs.scripps.edu/software.html

I use the program, WinMDI, and I swear by it.  You can do almost any kind of
regional analysis with stats in color, histograms, density plots, etc.  They
are all copyable and you can paste them directly into popular presentation
programs like freelance or powerpoint.  You can download several versions of
the program from these sites.  Good luck.



From owner-software@net.bio.net Tue Feb 03 22:00:00 1998
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From: zevsolltec@aol.com (ZevSolltec)
Newsgroups: bionet.software
Subject: Re: Alpha Innotech ProScan RFLP software - Opinions?
Date: 4 Feb 1998 15:16:03 GMT
Lines: 17
Message-ID: <19980204151601.KAA28513@ladder02.news.aol.com>
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References: <rrumpf-0302981344460001@128.146.74.139>

Dear Dr. Rumpf,

If you prefer Mac software, see our website or contact me for more information.

Best regards,
Zev
---------------------------------------------------------------------------
Zev Sunleaf
Vice President
Solltech, Inc.
Technology Innovation Center
Oakdale, IA 52319
(319) 335-4702
(319) 335-4489 Fax
Email: ZevSolltec@aol.com
http://members.aol.com/ZevSolltec/DENDRON.html
---------------------------------------------------------------------------

From owner-software@net.bio.net Tue Feb 03 22:00:00 1998
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From: Dag Stenberg <stenberg@cc.helsinki.fi>
Newsgroups: bionet.software
Subject: Spectral analysis of EEG
Date: 4 Feb 1998 07:29:00 GMT
Organization: University of Helsinki
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A colleague asked the following:
- he has sampled EEG data and feels able to convert this into any other
digital format
- he wants to do FFTs and postprocessing of spectral parameters, but
does not want to buy a complete sampling-analysis package (like Spike2,
Datawave, CVMS etc.), because of the cost
- What ready-made software could he get, so he does not have to find
somebody to write spectral analysis programs for the umpteenth time
in history?

Dag Stenberg
Spike2 and Datawave user
------------------------------------------------------------------
Dag Stenberg     MD PhD                    stenberg@cc.helsinki.fi
Institute of Biomedicine		   tel: (int.+)358-9-1918532
Department of Physiology                   fax: (int.+)358-9-1918681
P.O.Box 9        (Siltavuorenpenger 20 J)   
FIN-00014 University of Helsinki,Finland   
------------------------------------------------------------------



From owner-software@net.bio.net Tue Feb 03 22:00:00 1998
Path: biosci!agate!howland.erols.net!news.maxwell.syr.edu!uninett.no!sn.no!nntp.uio.no!funny.bahnhof.se!not-for-mail
From: Per Kraulis <pjk@avatar.se>
Newsgroups: bionet.software
Subject: Re: software to print protein structure images
Date: Wed, 04 Feb 1998 19:01:57 +0100
Organization: Avatar Software AB
Lines: 19
Message-ID: <34D8AD15.794B@avatar.se>
References: <6b4tdf$k79@mserv1.dl.ac.uk> <6b7o0c$pma$1@ulysses.noc.ntua.gr>
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chun ting zhang wrote:

> By what software (for PC) I can use to print out high quality 
> protein images, for example, ribbons or cartoons. 

You could try MolScript v2.0 which produces PostScript, VRML 2.0 and
Raster3D files from an input script and a PDB file. There is also an
OpenGL interactive graphics mode, and JPEG, PNG ad EPS image file output
formats, but these require additional libraries. The program is written
in C (ANSI), and reportedly compiles with GNU's gcc.

For more information, see the Official MolScript Web Site at

http://www.avatar.se/molscript/

where the documentation, license conditions (free for academics and
students) and distribution instructions can be found

/Per Kraulis

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!newsfeed.direct.ca!news-peer.sprintlink.net!news-peer-east.sprintlink.net!news.sprintlink.net!Sprint!rill.news.pipex.net!pipex!main.de.uu.net!Ireland.EU.net!HEAnet!web3.tcd.ie!acer.gen.tcd.ie!tpwalsh
From: tpwalsh@acer.gen.tcd.ie (Tom Walsh)
Newsgroups: bionet.software
Subject: Re: PDB amino acid positions
Date: 5 Feb 1998 14:07:28 GMT
Organization: INCBI
Lines: 28
Message-ID: <6bch30$lqo@web3.tcd.ie>
References: <34D98C11.41C6@cc.huji.ac.il>
NNTP-Posting-Host: acer.gen.tcd.ie

In article <34D98C11.41C6@cc.huji.ac.il>,
Iddo Friedberg  <idoerg@cc.huji.ac.il> wrote:
>Hi All,
>
>Does anybody know of a good, robust  program which will accept a PDB
>file as input, and for the output deliver for each amino acid it's PDB
>position number. Including such vagaries as negative numbering (some
>files have them), and non-numerical positions (as in serine proteinases,
>where there are such things as 65A). 
>

 If I've understood the problem correctly, it should be trivial in AWK.

   Tom Walsh

>Please reply by email, as well as to this newsgroup.
>
>
>Many thanks,
>
>Iddo
>


-- 

 - You talk to me of nationality, language, religion. I shall try to fly by 
   those nets.

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!woodstock.news.demon.net!demon!bullseye.news.demon.net!demon!mega.demon.nl!not-for-mail
From: "Mellow Yellow" <postbus@mega.demon.nl>
Newsgroups: bionet.software
Subject: LQQKING FOR NEW SOFTWARE LIST??
Date: Thu, 5 Feb 1998 06:30:58 +0100
Message-ID: <886656676.8992.0.rover.c3adec73@news.demon.nl>
NNTP-Posting-Host: mega.demon.nl
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Lines: 26

Zijn jullie op zoek naar de nieuwste software en games cd's???

Dan zijn jullie aan het goede adres.

wij leveren o.a :

Crazy Bites
Legacy
Twilight
Holland With love
Mega Pack
en nog veel meer meer meer.

Wij zijn misschien niet de goedkoopste maar wel de beste.!!!!

Voor vragen of suggesties kunt mailen naar postbus@mega.demon.nl

Wilt U kijken op onze site dat kan ook http:\\www.tmyt.demon.nl

Verder wensen wij U veel plezier en hopen dat wij wat voor U kunnen doen.


Met vriendelijke groet: Mellow & Yellow.




From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
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From: "Luis Santos" <las@mail.telepac.pt>
Newsgroups: bionet.software
Subject: First Sense
Date: Thu, 5 Feb 1998 13:40:41 -0000
Lines: 5
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Anyone can tell me where to buy it.

Thanks.



From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
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From: islam <islam@icrf.icnet.uk>
Newsgroups: bionet.software
Subject: Re: PDB amino acid positions
Date: Thu, 05 Feb 1998 14:12:33 +0000
Organization: Imperial Cancer Research Fund
Lines: 32
Message-ID: <34D9C8D1.167E@icrf.icnet.uk>
References: <34D98C11.41C6@cc.huji.ac.il>
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Iddo,

This is a straight forward request, but for which platforms
do you need the program and how do you want the output format ?
One word of caution - there may be missing residues in the data
in which case the numbering may not truly represent the numberical
order of the residues.

Iddo Friedberg wrote:
> 
> Hi All,
> 
> Does anybody know of a good, robust  program which will accept a PDB
> file as input, and for the output deliver for each amino acid it's PDB
> position number. Including such vagaries as negative numbering (some
> files have them), and non-numerical positions (as in serine proteinases,
> where there are such things as 65A).
> 
> Please reply by email, as well as to this newsgroup.
> 
> Many thanks,
> 
> Iddo
____________________________________________
Suhail A Islam
Biomolecular Modelling Laboratory
Imperial Cancer Research Fund, P.O. Box 123
44 Lincoln's Inn Fields, London WC2A 3PX
Tel: (0171) 269 3380, Fax: (0171) 269 3258
email: islam@icrf.icnet.uk
http://www.icnet.uk/bmm/
____________________________________________

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!134.222.90.2!EU.net!sun4nl!star.cs.vu.nl!bio.vu.nl!usenet
From: renej@bio.vu.nl
Newsgroups: bionet.software
Subject: Re: Spectral analysis of EEG
Date: Thu, 05 Feb 1998 10:08:43 +0100
Organization: VU Biology, Amsterdam, The Netherlands
Lines: 20
Message-ID: <34D9819B.A3C@bio.vu.nl>
References: <6b95bs$h88$1@oravannahka.Helsinki.FI>
NNTP-Posting-Host: 130.37.80.7
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.04Gold (WinNT; I)

Dag Stenberg wrote:
> 
> A colleague asked the following:
> - he has sampled EEG data and feels able to convert this into any other
> digital format
> - he wants to do FFTs and postprocessing of spectral parameters, but
> does not want to buy a complete sampling-analysis package (like Spike2,
> Datawave, CVMS etc.), because of the cost
> - What ready-made software could he get, so he does not have to find
> somebody to write spectral analysis programs for the umpteenth time
> in history?
> 

Try the package SANTIS at:

	http://www.physiology.rwth-aachen.de/santis/

Hope this helps

RJ

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!NCBI.NLM.NIH.GOV!francis
From: francis@NCBI.NLM.NIH.GOV
Newsgroups: bionet.software
Subject: Re: Web translation utility
Date: 5 Feb 1998 06:55:36 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 33
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802051454.JAA12430@borduas.nlm.nih.gov>
NNTP-Posting-Host: net.bio.net


> From BIOSCI-REQUEST@net.bio.net Thu Feb  5 09:42:05 1998

> Could someone point me to a web translation utility? I simply want to input a
> DNA sequence and (after defining the reading frame), get back the peptide
> sequence. Does NCBI have a utility like this?
> 
> Answer by email, please sjhogart@unity.ncsu.edu

yes, we do:

from our home page you can get to the orf-finder:

http://www.ncbi.nlm.nih.gov/gorf/gorf.html

cheers,

f.

--
| B.F. Francis Ouellette  
| GenBank Coordinator
|
| francis@ncbi.nlm.nih.gov   



> -- 
> Susan
> "Suicide is the most sincere form of self-criticism." - Anon      
> http://www4.ncsu.edu/unity/users/s/sjhogart/public/home.html
> 
> 

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!206.229.87.25!news-peer.sprintlink.net!news-backup-east.sprintlink.net!news-in-east.sprintlink.net!news.sprintlink.net!Sprint!199.125.85.9!news.mv.net!newspump.wustl.edu!newsreader.wustl.edu!not-for-mail
From: reece@whoville.wustl.edu
Newsgroups: bionet.software
Subject: Re: PDB amino acid positions
Date: 05 Feb 1998 17:48:34 -0600
Organization: Biophysics & Biochemistry, Washington University, St. Louis, USA
Lines: 40
Message-ID: <82afc5r4tp.fsf@whoville.wustl.edu>
References: <34D98C11.41C6@cc.huji.ac.il>
Reply-To: Reece Kimball Hart <reece@dasher.wustl.edu>
NNTP-Posting-Host: whoville.wustl.edu
To: Iddo Friedberg <idoerg@cc.huji.ac.il>
X-Attribution: Reece
X-URL: <URL:http://dasher.wustl.edu/~reece/>
X-Newsreader: Gnus v5.5/Emacs 20.2

-----BEGIN PGP SIGNED MESSAGE-----

>>>>> IF == Iddo Friedberg <idoerg@cc.huji.ac.il> wrote 
>>>>> In bionet.software
>>>>> On Thu, 05 Feb 1998 11:53:21 +0200
>>>>> Re PDB amino acid positions

IF> Does anybody know of a good, robust  program which will accept a PDB
IF> file as input, and for the output deliver for each amino acid it's PDB
IF> position number.

If I understand correctly, you want the ordinal position of each amino
acid.

perl -ne 'if (/ATOM.{13}(...)...(....)/ and not $seen{$2}++) \
  {printf("%3d $1\n",++$o)}' file.pdb

(don't type the '\')

The above worked on a test with perl 5.004_03 (type perl -v), 1hvr (2
chains) and 3ptb (discontinuous numbering).  Whether it's 'good' or
'robust' depends on your needs, but I hope this helps.

perl is freely available from www.perl.com.

- -- 
Reece Hart, http://dasher.wustl.edu/~reece/
Do not send unsolicited bulk email.  Boycott companies which do so.

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From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Newsgroups: bionet.xtallography,bionet.software
Path: biosci!daresbury!uninett.no!Cabal.CESspool!bofh.vszbr.cz!newscore.univie.ac.at!newsfeed.ecrc.net!207.41.200.131.MISMATCH!news-pen-1.sprintlink.net!news-east.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.internetmci.com!209.95.128.196!news-nyc.telia.net!masternews.telia.net!newsfeed.sunet.se!news99.sunet.se!news01.sunet.se!130.237.207.77.MISMATCH!news.ki.se!news
From: Guoguang Lu <guoguang@alfa.mbb.ki.se>
Subject: Improve version of the TOP software package for protein structure comparisons
Sender: news@news.ki.se (News admin)
Message-ID: <34DA08DE.4899@alfa.mbb.ki.se>
Date: Thu, 5 Feb 1998 18:45:50 GMT
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Lines: 37
Xref: biosci bionet.xtallography:4037 bionet.software:20429

Improve version of the TOP software package for automatic 			
comparison of 3-d protein structures

The TOP program for automatic comparisons of protein structures has been
recently improved. The new version for unix computers can be obtained
via FTP. The new version of Web server has been also installed. Please
see http://gamma.mbb.ki.se/~guoguang/webtop/wwwtop.html

The most significant improvement is in seraching similar structures in
database. The users of old version complained about the program outputs
too much infomration (noise) which is diffult to get the point. The new
version gives parameters of "Structure Diveristy" and "Topological
Diversity" which rank the similarity between homologous structures. It
is much easier for users to find the their most similar structures in
the search and igored the noise.

The new version is able to find sequence permutations in the comparisons
This will help to find homologous structures which is missed the other
software with similar functions.

Some part of the document mightbe still confusing. I need feed back from
users to fix it. It is also welcome to complain about any problems of
Web server and unix computers.

-- 
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Guoguang Lu, PhD, Research Scientist
Division of Molecular Structural Biology	
Department of Medical Biochemistry and Biophysics 
Doktorsringen 9A1
Karolinska Institute
17177 Stockholm
Sweden
---------------------------------------------------------------------
Phone: (int+46)-8-728 7651(o)   Email:    guoguang@alfa.mbb.ki.se
Fax:   (int+46)-8-327626   Homepage: http://gamma.mbb.ki.se/~guoguang
+++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!europa.clark.net!208.134.241.18!newsfeed.internetmci.com!206.252.192.28!news.stealth.net!news.ibm.net.il!ibm.net!news.biu.ac.il!news.huji.ac.il!not-for-mail
From: Iddo Friedberg <idoerg@cc.huji.ac.il>
Newsgroups: bionet.software
Subject: PDB amino acid positions
Date: Thu, 05 Feb 1998 11:53:21 +0200
Organization: The Hebrew University, Jerusalem
Lines: 21
Message-ID: <34D98C11.41C6@cc.huji.ac.il>
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Hi All,

Does anybody know of a good, robust  program which will accept a PDB
file as input, and for the output deliver for each amino acid it's PDB
position number. Including such vagaries as negative numbering (some
files have them), and non-numerical positions (as in serine proteinases,
where there are such things as 65A). 

Please reply by email, as well as to this newsgroup.


Many thanks,

Iddo

--
Iddo Friedberg
Phone: (972)-2-6758647
email: idoerg@cc.huji.ac.il
web: http://www.ls.huji.ac.il/~idoerg
More info: finger idoerg@cc.huji.ac.il

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news.maxwell.syr.edu!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!not-for-mail
From: pd213@cam.ac.uk (Phil Davey)
Newsgroups: bionet.software
Subject: Re: Web translation utility
Date: 5 Feb 1998 16:50:14 GMT
Organization: University of Cambridge, England
Lines: 26
Sender: pd@napc8.path.cam.ac.uk
Message-ID: <6bcqk6$569$1@lyra.csx.cam.ac.uk>
References: <199802051454.JAA12430@borduas.nlm.nih.gov>
Reply-To: pd213@cam.ac.uk
NNTP-Posting-Host: napc8.path.cam.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
X-Newsreader: knews 0.9.8

In article <199802051454.JAA12430@borduas.nlm.nih.gov>,
	francis@NCBI.NLM.NIH.GOV writes:
>> From BIOSCI-REQUEST@net.bio.net Thu Feb  5 09:42:05 1998
>> Could someone point me to a web translation utility? I simply want to 
>> input a DNA sequence and (after defining the reading frame), get back
>> the peptide sequence. Does NCBI have a utility like this?
> 
> yes, we do:
> 
> from our home page you can get to the orf-finder:
> 
> http://www.ncbi.nlm.nih.gov/gorf/gorf.html

You could also try a program I have written. It's called Sequence Tool
and is at http://www.path.cam.ac.uk/~pd/tool_multi.html
A slightly modified version which will process lots of sequences at once
(as long as they are in fasta format) is at
http://www.path.cam.ac.uk/~pd/tool_test.html

At the moment it will optionally reformat, reverse complement, translate
(in any frame) and print a simple base composition.

Let me know what you think if you decide to try it out.  
-- 
Phil
[E-mail pd213@cam.ac.uk]

From owner-software@net.bio.net Wed Feb 04 22:00:00 1998
Newsgroups: bionet.software
Path: biosci!agate!logbridge.uoregon.edu!news-peer.gip.net!news.gsl.net!gip.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.nacamar.de!uni-erlangen.de!news-nue1.dfn.de!news-lei1.dfn.de!news-ber1.dfn.de!news-ham1.dfn.de!news-han1.dfn.de!news.uni-bielefeld.de!techfak.uni-bielefeld.de!fuellen
From: fuellen@PLEASE_REMOVE_THIS_SPAM_BLOCKER.techfak.uni-bielefeld.de (Georg Fuellen)
Subject: Re: bioinformatics?
Message-ID: <Enx6Jy.MHu@hermes.hrz.uni-bielefeld.de>
Sender: fuellen@TechFak.Uni-Bielefeld.DE (Georg Fuellen)
Cc: fuellen
Date: Thu, 5 Feb 1998 19:09:33 GMT
To: "James Yegerlehner" <yeger@completebbs.com>
Reply-To: fuellen
References:  <6b2n9v$87p$1@spk-news1.nwnexus.com>
NNTP-Posting-Host: schilf.techfak.uni-bielefeld.de
Organization: Universitaet Bielefeld, Technische Fakultaet.
X-Newsreader: xrn 8.01
Lines: 22

In article <6b2n9v$87p$1@spk-news1.nwnexus.com>, "James Yegerlehner" <yeger@completebbs.com> writes:
|> Hello-
|> Can anyone point me to a directory of bioinformatics programs of study and
|> their universities?

Take a look at 
http://www.iscb.org/training.html

A collection of course syllabi is also available via
http://www.techfak.uni-bielefeld.de/bcd/Curric/syllabi.html
Any comments, additions, corrections, etc would be welcome !

best wishes,
Georg Fuellen
Univ. Bielefeld, Research Group in Practical Comp. Science
http://www.techfak.uni-bielefeld.de/bcd/welcome.html

|> Thanks in advance,
|> Jim
|> 
|> 
|> 

From owner-software@net.bio.net Thu Feb 05 22:00:00 1998
Path: biosci!agate!howland.erols.net!europa.clark.net!152.158.16.55!newsfeed2.uk.ibm.net!ibm.net!newsgate.cistron.nl!het.net!news.worldonline.nl!not-for-mail
From: "joris" <aplusr@worldonline.nl>
Newsgroups: bionet.software
Subject: PC as answeringmachine?
Date: 6 Feb 1998 15:15:31 GMT
Organization: World Online
Lines: 8
Message-ID: <01bd330c$67d0c040$LocalHost@aplusr>
NNTP-Posting-Host: dlft1-p182.worldonline.nl
X-Newsreader: Microsoft Internet News 4.70.1157

Does anyone know of software available which can make a pc and modem work
as an answeringmachine, including soundrecording (for instance in *.wav
files)?
I would be very grateful for an answer and/or a tip.
Thanks a lot,

Joris.


From owner-software@net.bio.net Thu Feb 05 22:00:00 1998
Path: biosci!agate!ihnp4.ucsd.edu!sdd.hp.com!usc!howland.erols.net!woodstock.news.demon.net!demon!dispose.news.demon.net!demon!peer.news.zetnet.net!zetnet.co.uk!user-10002114.zetnet.co.uk!not-for-mail
From: JGW Computing <jgw.computing@zetnet.co.uk>
Newsgroups: bionet.software
Subject: Re: Sample organiser software
Date: Fri, 6 Feb 1998 13:53:47 GMT
Message-ID: <1998020613534771355@zetnet.co.uk>
References: <1998012511425771355@zetnet.co.uk>
NNTP-Posting-Host: user-10002114.zetnet.co.uk
X-Mailer: ZIMACS Version 1.20c 10002114
Lines: 34

The message <1998012511425771355@zetnet.co.uk>
  from  JGW Computing <jgw.computing@zetnet.co.uk> contains these words: 


> Have you wasted lots of time looking for a blood sample you knew you 
> had received? Or spent ages sorting samples into order, so that you 
> can find them later?
> Then Finder! is for you.

> All you do is place your sample into a rack, then enter the sample 
> number into Finder! When you want to find the sample again, ask 
> Finder!, and it will tell you where it's stored. Brilliant, but simple.

> Visit http://www.users.zetnet.co.uk/jgw.computing/ to download a 
> function limited working program, including a quick start guide.

> Contact JGW Computing by email to:

> jgw.computing@zetnet.co.uk

Later version now available on the web site. Changes include:
* sample numbers can contain characters, digits and decimal points
* range checks on all the above
* length of sample number increased to 12 characters per number
* more comprehensive bar-code entry setup
* limited testing of bar-code entry with new bar-code reader 
configuration option








From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Date: Sat, 07 Feb 1998 01:30:14 +0100
From: gerard@xray.bmc.uu.se (Gerard Kleywegt)
Newsgroups: bionet.software
Subject: Re: PDB amino acid positions
Message-ID: <gerard-0702980130140001@nostromo.bmc.uu.se>
References: <34D98C11.41C6@cc.huji.ac.il>
Organization: SBNet - Uppsala University
X-Newsreader: Value-Added NewsWatcher 2.1d3+
NNTP-Posting-Host: nostromo.bmc.uu.se
Lines: 25
Path: biosci!agate!howland.erols.net!newsfeed.internetmci.com!194.162.162.196!newsfeed.nacamar.de!uninett.no!newsfeed.sunet.se!news99.sunet.se!news01.sunet.se!130.238.7.13.MISMATCH!newsfeed.uu.se!nostromo.bmc.uu.se!user

In article <34D98C11.41C6@cc.huji.ac.il>, Iddo Friedberg
<idoerg@cc.huji.ac.il> wrote:

>Hi All,
>
>Does anybody know of a good, robust  program which will accept a PDB
>file as input, and for the output deliver for each amino acid it's PDB
>position number. Including such vagaries as negative numbering (some
>files have them), and non-numerical positions (as in serine proteinases,
>where there are such things as 65A). 
>
>Please reply by email, as well as to this newsgroup.
>
>
>Many thanks,
>
>Iddo

cat filename.pdb | grep ^ATOM | grep CA | cut -c18-27

--cd
----------------------------------------------------------
Gerard Kleywegt
mailto:gerard@xray.bmc.uu.se
http://alpha2.bmc.uu.se/~gerard/

From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!agate!howland.erols.net!news-peer.sprintlink.net!news-pen-15.sprintlink.net!newsfeed.nysernet.net!news.nysernet.net!news.sprintlink.net!Sprint!24.129.0.46!newsfeed.se.mediaone.net!baker.se.mediaone.net!news@ccse.net
From: "Jack_D" <jdieck@mediaone.net>
Newsgroups: bionet.software
Subject: NetConnect
Date: Sat, 7 Feb 1998 06:15:02 -0000
Organization: MediaOne Express
Lines: 19
Message-ID: <6bhfug$2q67@baker.se.mediaone.net>
NNTP-Posting-Host: 24.129.28.74
X-Newsreader: Microsoft Outlook Express 4.71.1712.3
X-MimeOLE: Produced By Microsoft MimeOLE V4.71.1712.3

Beware of a company known as NetConnect, Inc. doing business out of Markham,
Ontario.  This company was once known as Markham Computer Corporation.  They
had offices in Boca Raton, FL. and are marketing a product known as
NetSupport Manager.  This company skipped out of the United States in the
middle of the night, leaving employees and vendors holding the bag.  Even
personal property was taken to Canada against the owner’s wishes, and has
yet to be returned.  The owners of this company, the Batra’s, also run a
company call Batra International.  DON’T DO BUSINESS WITH THESE PEOPLE, they
cannot be trusted.  Court records show that they’ve skipped out of the U.S.
to avoid paying outstanding bills.  Try collecting something from someone in
a foreign country.  Senator Bob Graham of Florida is pursuing this case with
the United States Justice Department.  Again, be very wary about doing any
kind of business with these people.
Please pass this along to each agency that you think might have a need to
know.





From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!GENOME.BIOTECH.WASHINGTON.EDU!eugene
From: eugene@GENOME.BIOTECH.WASHINGTON.EDU (Eugene Kolker)
Newsgroups: bionet.software
Subject: Recomb98: student financial support
Date: 6 Feb 1998 16:16:30 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 34
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802070014.QAA08372@genome.biotech.washington.edu>
NNTP-Posting-Host: net.bio.net


Thanks to the generosity of our governmental and corporate sponsors,
limited financial support for travel expenses will be available for
students attending RECOMB 98. Support is offered on a competitive
basis.  In order to apply for financial support, you must:

1) be a graduate student or undergraduate student attending RECOMB 98,

2) register for RECOMB 98 including the submission of registration fees
   by Feb. 20, 1998,

3) submit a one page essay describing why you should receive financial
   support.

The essay (up to *500* words) should include the following information:

        i) your name,
       ii) your email address,  
      iii) the school you are attending,
       iv) the professor who is overseeing your research,
        v) a short description of your research,
       vi) the paper title if you have a paper at RECOMB 98,
        v) a short description of your research,
       vi) the paper title if you have a paper at RECOMB 98,
      vii) the poster title if you have a poster at RECOMB 98,
     viii) any other information that you think would be relevant.

The essay should be sent via email to support@ecology.biomath.mssm.edu
by Feb. 20, 1998. Those students selected for financial support will
be notified by email on or before March 9, 1998.


Early registration    ends February 20, 1998!
Hotel conference rate ends February 24, 1998!

From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!agate!howland.erols.net!sunqbc.risq.qc.ca!newsflash.concordia.ca!not-for-mail
From: Riccardo Telaro <r_telar@alcor.concordia.ca>
Newsgroups: bionet.software
Subject: E. Coli gene sequencing software
Date: Sat, 07 Feb 1998 12:56:47 -0500
Organization: Concordia University
Lines: 40
Message-ID: <34DCA05F.379BE0F9@alcor.concordia.ca>
NNTP-Posting-Host: alcor.concordia.ca
Mime-Version: 1.0
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X-Mailer: Mozilla 4.04 [en] (Win95; I)


--------------DEABDDBA2553373F223784A1
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit

Hi there,

I'm looking for some good interesting Windows 95 software on molecular
biological techniques.

I'm currently working on a project which has to do with cloning and
sequencing the Gal P gene in E. Coli.

Can any one suggest me a program that will conduct restriction analysis,
mapping, vector usage and so on all in one program.

Thanx

--------------DEABDDBA2553373F223784A1
Content-Type: text/html; charset=us-ascii
Content-Transfer-Encoding: 7bit

<HTML>


<P>Hi there,

<P>I'm looking for some good interesting Windows 95 software on molecular
biological techniques.

<P>I'm currently working on a project which has to do with cloning and
sequencing the <I>Gal P</I> gene in E. Coli.

<P>Can any one suggest me a program that will conduct restriction analysis,
mapping, vector usage and so on all in one program.

<P>Thanx</HTML>

--------------DEABDDBA2553373F223784A1--


From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!GENOME.BIOTECH.WASHINGTON.EDU!eugene
From: eugene@GENOME.BIOTECH.WASHINGTON.EDU (Eugene Kolker)
Newsgroups: bionet.software
Subject: Recomb98: student financial support
Date: 6 Feb 1998 16:16:33 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 34
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802070014.QAA08378@genome.biotech.washington.edu>
NNTP-Posting-Host: net.bio.net


Thanks to the generosity of our governmental and corporate sponsors,
limited financial support for travel expenses will be available for
students attending RECOMB 98. Support is offered on a competitive
basis.  In order to apply for financial support, you must:

1) be a graduate student or undergraduate student attending RECOMB 98,

2) register for RECOMB 98 including the submission of registration fees
   by Feb. 20, 1998,

3) submit a one page essay describing why you should receive financial
   support.

The essay (up to *500* words) should include the following information:

        i) your name,
       ii) your email address,  
      iii) the school you are attending,
       iv) the professor who is overseeing your research,
        v) a short description of your research,
       vi) the paper title if you have a paper at RECOMB 98,
        v) a short description of your research,
       vi) the paper title if you have a paper at RECOMB 98,
      vii) the poster title if you have a poster at RECOMB 98,
     viii) any other information that you think would be relevant.

The essay should be sent via email to support@ecology.biomath.mssm.edu
by Feb. 20, 1998. Those students selected for financial support will
be notified by email on or before March 9, 1998.


Early registration    ends February 20, 1998!
Hotel conference rate ends February 24, 1998!

From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!daresbury!uninett.no!news.maxwell.syr.edu!logbridge.uoregon.edu!arclight.uoregon.edu!news.cc.ukans.edu!not-for-mail
From: Mousheng Xu <mxu@eecs.ukans.edu>
Newsgroups: bionet.software
Subject: UPDATE: Bioinformation Search Center 4.0
Date: Sat, 07 Feb 1998 16:54:19 -0600
Organization: University of Kansas Computing Services
Lines: 27
Message-ID: <34DCE61B.FF6@eecs.ukans.edu>
NNTP-Posting-Host: blizzard.rsl.ukans.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (X11; I; OSF1 V4.0 alpha)

Dear Scientists:
        The Bioinformation Search Center (BSC) 4.0
(http://www.ittc.ukans.edu/~mxu/cgi-bin/thesis/bi.cgi) is now available
to the public!
        Major new features of Version 4.0:
 	1. Short words are allowed for search. For example, in the previous
versions of BSC, the "IX" of "human factor IX" was not used in search,
but in BSC 4.0, it is used.
	2. Keywords are highlighted in the results.

	Major known problem:
	Common words are not used for search in BSC. For the above example,
both "human" and "factor" are so common that they are not used for
search. In this case, it is bad. But a lot of common words such as
"the", "a", "an" are surely bad in search of biological information.
This problem can easily be solved, technically. But it takes
programmer's time and the university's computer disk space.
	
        
        Please give this baby a try!
        Any comments are highly appreciated!
        
        Please see below for the brief introduction to BSC.
        Thanks a lot.

Sincerely,
Mousheng Xu

From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!agate!ihnp4.ucsd.edu!sdd.hp.com!vixen.cso.uiuc.edu!news2.chicago.iagnet.net!qual.net!iagnet.net!203.29.160.2!ihug.co.nz!clear.net.nz!news.hn.netlink.co.nz!canterbury.ac.nz!not-for-mail
From: Mark Silby <mws33@student.canterbury.ac.nz>
Newsgroups: bionet.software
Subject: Helix-Turn-Helix
Date: Sun, 08 Feb 1998 10:32:40 -0800
Organization: University of Canterbury
Lines: 13
Message-ID: <34DDFA48.27A1@student.canterbury.ac.nz>
NNTP-Posting-Host: 132.181.220.90
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0 (Win16; I)

Hi all

I am investigating a putative DNA binding protein, and am interested in
aquiring a program that can be used to predict helix-turn-helix motifs
based upon the predicted protein sequence.  Any suggestions of shareware
or commercial programs would be appreciated.

Cheers,
Mark Silby
Department of Plant and Microbial Sciences
University of Canterbury
Christchurch
New Zealand.

From owner-software@net.bio.net Fri Feb 06 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!arclight.uoregon.edu!news.cc.ukans.edu!not-for-mail
From: Mousheng Xu <mxu@eecs.ukans.edu>
Newsgroups: bionet.software
Subject: !!! HELP-SURVEY-BONUS: BSC 4.0 !!!
Date: Sat, 07 Feb 1998 17:01:51 -0600
Organization: University of Kansas Computing Services
Lines: 9
Message-ID: <34DCE7DF.52BF@eecs.ukans.edu>
NNTP-Posting-Host: blizzard.rsl.ukans.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (X11; I; OSF1 V4.0 alpha)

Dear Scientists:
	Please see my last post titled as "UPDATE: Bioinformation Search Center
4.0" for introduction about 4.0.
	The one who finishes the survey of BSC will get the following bonus:
	1. Core codes of the whole BSC system.
	2. My thanks to you.


-- Mousheng Xu

From owner-software@net.bio.net Sat Feb 07 22:00:00 1998
From: "John Taylor" <taylor35@email.msn.com>
Subject: Card Collecting Software
Message-ID: <01bd342c$53963440$3d442499@gobraves>
X-Newsreader: Microsoft Internet News 4.70.1155
Newsgroups: bionet.software
Date: Sat, 07 Feb 1998 16:55:02 -0800
Path: biosci!bloom-beacon.mit.edu!news.kodak.com!news-pen-16.sprintlink.net!newsfeed.nysernet.net!news.nysernet.net!207.41.200.14!news-pen-14.sprintlink.net!206.229.87.26!news-east.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.internetmci.com!207.68.152.12!upnetnews01!upnetnews03
Lines: 12

Hi, if you have time please go to http://www.picknclick.com and download
the demo version of this software. It's called The Ultimate Card Collector!
and
it's software that card collectors can use to get organized. There are over
170,000 preloaded cards that help to cut down on manual entries. The
software also has the ability to create a shopping list of cards you are
missing and it will let you do a lot of other things.

Regards,

John Taylor


From owner-software@net.bio.net Sat Feb 07 22:00:00 1998
Path: biosci!agate!howland.erols.net!Supernews73!supernews.com!Supernews69!not-for-mail
From: "Andrew Miller" <amiller@infohouse.com>
Newsgroups: bionet.software
Subject: free medical image 3D visualization software for Windows95/NT
Date: Sun, 8 Feb 1998 12:22:31 -0500
Organization: All USENET -- http://www.Supernews.com
Lines: 18
Message-ID: <6bkq0s$akd$1@usenet50.supernews.com>
NNTP-Posting-Host: 10893@206.30.88.62
Mime-Version: 1.0
Content-Type: text/plain;
	charset="iso-8859-1"
Content-Transfer-Encoding: 7bit
X-Newsreader: Microsoft Outlook Express 4.72.2106.4
X-MimeOLE: Produced By Microsoft MimeOLE V4.72.2106.4

Just to let you know,

There's a freeware application for Windows95/NT called NeuroModeller
(version 1.09) developed by Cornell Medical Center, Division of
Neurosurgery, that allows 3D reconstruction of medical slice images.
Available for download at:

http://users.infohouse.com/amiller/home.htm

... approximately 640 KB in size. Currently reads DICOM and BMP slice file
fomats.


Sincerely,
                      Andrew Miller, MD
                      amiller@infohouse.com



From owner-software@net.bio.net Sat Feb 07 22:00:00 1998
Path: biosci!agate!howland.erols.net!woodstock.news.demon.net!demon!dispose.news.demon.net!demon!peer.news.zetnet.net!zetnet.co.uk!user-10002114.zetnet.co.uk!not-for-mail
From: Garth Williams <garth.williams@zetnet.co.uk>
Newsgroups: bionet.software
Subject: Re: PC as answeringmachine?
Date: Fri, 6 Feb 1998 23:14:42 GMT
Message-ID: <1998020623144271355@zetnet.co.uk>
References: <01bd330c$67d0c040$LocalHost@aplusr>
NNTP-Posting-Host: user-10002114.zetnet.co.uk
X-Mailer: ZIMACS Version 1.20c 10002114
Lines: 31

The message <01bd330c$67d0c040$LocalHost@aplusr>
  from  "joris" <aplusr@worldonline.nl> contains these words: 


> Does anyone know of software available which can make a pc and modem work
> as an answeringmachine, including soundrecording (for instance in *.wav
> files)?
> I would be very grateful for an answer and/or a tip.
> Thanks a lot,

> Joris.

Hi Joris,

The Quicklink message centre software supplied as standard with my 
USR sportster external modem about 18 months ago includes options to 
set the modem and pc up as an answering machine. The modem includes a 
small internal microphone which is adequate to record an answering 
machine message. The software can be set up for multiple mailboxes, 
such as "Press 1 for sales, 2 for orders" etc. as well. The PC can be 
left on "listening" to the phone, and will respond to incoming calls ok.

Regards,


-- 
Garth Williams,
Worcester.
email: garth.williams@zetnet.co.uk
www:   http://www.users.zetnet.co.uk/jgw.computing/


From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!howland.erols.net!fu-berlin.de!news-ber1.dfn.de!news-ham1.dfn.de!news.mu-luebeck.de!not-for-mail
From: "Lars Komorowski" <larskomo@physik.mu-luebeck.de>
Newsgroups: bionet.software
Subject: Driver for Pharmacia HPLCManager 3.0
Date: Mon, 9 Feb 1998 14:12:48 +0100
Organization: Med. Universitaet zu Luebeck
Lines: 5
Message-ID: <6bmvk4$hhi$1@gwsun.medinf.mu-luebeck.de>
NNTP-Posting-Host: 141.83.167.168
X-Newsreader: Microsoft Outlook Express 4.71.1712.3
X-MimeOLE: Produced By Microsoft MimeOLE V4.71.1712.3

I need printer drivers for HPLCManager 3.0 from Pharmacia for DOS. Who has
got the installation disks ?
Lars Komorowski



From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news-peer.gip.net!news.gsl.net!gip.net!howland.erols.net!news.starnet.net!newsreader.wustl.edu!not-for-mail
From: Sean Eddy <eddy@wrasse.wustl.edu>
Newsgroups: bionet.software
Subject: Re: annotating EST sequence information with BLAST search output
Date: 09 Feb 1998 07:46:31 -0600
Organization: Washington University in St. Louis
Lines: 35
Message-ID: <u9zpk0gabs.fsf@wrasse.wustl.edu>
References: <199802090426.XAA02664@borduas.nlm.nih.gov>
NNTP-Posting-Host: wrasse.wustl.edu
X-Newsreader: Gnus v5.3/Emacs 19.34

francis@BORDUAS.NLM.NIH.GOV (Francis Ouellette) writes:
> Why would one one to annotate any record with information
> which will be out of date the day it is printed?
> 
> I think we would want to discourage such annotations.

That's a valid point. But on the other hand, in many cases, the
annotation is useful, and much of the information does not go out of
date.

For example, if an EST has a 100% identity hit to a known gene, that
information is not going to change. 

A less clear case, but also useful: if an EST shows a blastx hit
against a well-known protein family (say, a transcription factor
family), that's also useful information, even if we don't know yet
exactly what gene the EST corresponds to.

> If you want to see what the record is related to, see the
> blast similarity which are computed in dbEST or in the related
> sequences to a record present in Entrez.  Loooking at 
> annotations which will never be updated is missleading,
> and uninformative.

That's too strong a position to take, I think. Scanning EST
description lines is far, far faster than clicking through to see a
whole dbEST record for each EST. Description lines should contain our
"best effort" to give a short description of the EST.

It's a user education problem to make sure people realize that those
description lines are bound to be outdated, and that they may be
misleading. But "uninformative" they're not, in my opinion.

- Sean


From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!prospect.anprod.csiro.au!d.adelson
From: d.adelson@prospect.anprod.csiro.au (Dave Adelson)
Newsgroups: bionet.software
Subject: annotating EST sequence information with BLAST search output
Date: 8 Feb 1998 19:49:32 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 18
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9802090345.AA15455@nugget.prospect.anprod.CSIRO.AU>
NNTP-Posting-Host: net.bio.net

G'day,

Does anyone know of a program similar to dfblast, which takes the BLAST
output and uses it to annotate the original query sequence?  

I have dblast, but can't make it do what it is supposed to.  

Please cc replies to my email address as I do not always get the time to
check USENET.

Cheers,

Dave
David Adelson, PhD -- Senior Research Scientist
CSIRO Division of Animal Production, Prospect, NSW,  Australia
Tel: +61 2 9840 2860
Fax: +61 2 9840 2939
All opinions are my own, not CSIRO's

From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!HYDRUS.CC.UNIUD.IT!cism
From: cism@HYDRUS.CC.UNIUD.IT (organizers)
Newsgroups: bionet.software
Subject: school-workshop announcement
Date: 9 Feb 1998 10:25:09 -0800
Organization: CISM
Lines: 140
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <34DF498D.3422@hydrus.cc.uniud.it>
NNTP-Posting-Host: net.bio.net

                             School-Workshop on

                            COMPUTATIONAL BIOLOGY

                              June 10-19, 1998

                             CISM, Udine, Italy

                                sponsored by

                      Italian National Research Council

                                   UNESCO

                             University of Udine

----------------------------------------------------------------------------

<*> General description

<*> Program

<*> Call for papers

<*> Information

<*> Organizing committee
----------------------------------------------------------------------------

                             General description

In the past few years, Computational Molecular Biology has emerged as a
prominent new active area of research, lying on the boundary of computer
science, mathematics, operations research, statistics and, of course,
molecular biology. Among the many problems studied in Computational
Molecular Biology we find

   * Genomic data search problems ( -> Stringology and Statistics )
   * DNA rearrangement problems ( -> Combinatorial Analysis )
   * Sequence alignment problems ( -> Combinatorial Optimization )
   * Construction of phylogenies ( -> Graph Theory )

The aim of this school is at providing a review of the most important
computational problems motivated by different applications in molecular
biology. In particular, results will be presented concerning the complexity
of the problems, provably good and/or efficient solutions, modeling and
statistical analysis. The school will last six days. The last two days will
be devoted to a workshop where contributed papers will be presented.

----------------------------------------------------------------------------

                                   Program

   * Basic concepts of molecular biology: R. Ravi - Carnegie Mellon
     University - Pittsburgh;
   * Computational challenges in gene-hunting: Pavel Pevzner - University of
     Southern California - Los Angeles;
   * Physical Mapping: Richard Karp - University of Washington - Seattle;
   * Sequence assembly: Eugene Myers - University of Arizona - Tucson;
   * Indexing Data Structures for Large Genomic DataBases: Paolo Ferragina -
     University of Pisa;
   * Algorithmic aspects of sequence comparison: Daniel Gusfield -
     University of California - Davis;
   * Pattern Matching Algorithms for Sequence Regularities and Statistics:
     Alberto Apostolico - University of Padua and Purdue University - West
     Lafayette;
   * Multiple sequence alignments: John Kececioglu - University of Georgia -
     Athens;
   * Phylogenetic reconstruction: Martin Farach - Rutgers University -
     Piscataway ;
   * Integrating phylogenetic reconstruction and multiple sequence
     alignments: Martin Vingron - Heidelberg;
   * Protein Folding and Structure Prediction Algorithms : Sorin Istrail -
     Sandia National Laboratories;
   * Shortest Paths, Hidden Markov Models and Weighted Automata: Raffaele
     Giancarlo - University of Palermo;

----------------------------------------------------------------------------

                               Call for papers

The last two days of the school-workshop will be devoted to contributed
lectures. Prospective lecturers are encouraged to submit by email an
extended abstract (up to four pages long), in postscript format, to any of
the organizers. Software presentations are also encouraged. The deadline for
submissions is February 28, 1998.

----------------------------------------------------------------------------

                                 Information

Registration

The registration fee is of 500,000 Italian lire, before March 31, 1998. A
late fee of 650,000 Italian lire applies after March 31, 1998. A limited
amount of scholarships will be available for participants in need of
financial support. Priority will be given to participants from eastern
european countries or developing countries. Applicants should send a CV to
the organizing committee by March 31, 1998.

   * Click here for an ASCII version of the registration form.
   * Click here for an HTML version of the registration form.
   * Click here for info on financial support.

Travel information

Udine is located in Friuli Venezia Giulia, North-East of Italy, 70
kilometers from Trieste and 110 kilometers from Venice. Here is a list of
hotels and a map of the city.

Traveling by air: The nearest airport is Trieste Airport, located 40
kilometers from Udine. There are daily connections to/from Rome and Milan,
and from Munich, Germany. A bus shuttle service to Udine is available in
connection to these flights. In alternative to Udine Airport, there is
Venice Airport, located 110 kilometers from Udine. From Venice-Mestre
railway station there are several trains to Udine.

Traveling by train: Udine can be reached from anywhere in Italy by train.
The following link provides a time table of daily trains in Italy. Or, click
on this link for a time table of trains between European countries .

Contact address: Segreteria CISM, Piazza Garibaldi 18, 33100 Udine. Tel.
+39-432-294989. Fax +39-432-501523. Email: cism@hydrus.cc.uniud.it



----------------------------------------------------------------------------

                            Organizing committee

The coordinators of the School-Workshop are:

   * R. Ravi - Carnegie Mellon Universiy- Pittsburgh
   * P. Serafini - University of Udine
   * G. Lancia - University of Padova

                   --------------------------------------

<*> Back to CISM home page


From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!GENOME.BIOTECH.WASHINGTON.EDU!eugene
From: eugene@GENOME.BIOTECH.WASHINGTON.EDU (Eugene Kolker)
Newsgroups: bionet.software
Subject: Recomb98: Deadlines & Preliminary Program
Date: 9 Feb 1998 11:08:07 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 356
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802091906.LAA01480@genome.biotech.washington.edu>
NNTP-Posting-Host: net.bio.net


Early registration    ends  February 20, 1998!
Hotel conference rate ends  February 24, 1998!

For more details please visit our web site:
http://www.mssm.edu/biomath/recomb98.html

----------------------------------------------------------------------------

RECOMB 98 SCHEDULE

Saturday, March 21, 1998

7:00 pm - 10:00 pm	Welcome Reception 
Renaissance Room


Sunday, March 22, 1998

8:45 am  		Opening Remarks
Embassy Ballroom

	Pavel Pevzner,  RECOMB 1998 Program Committee Chair 

	Gary Benson,    RECOMB 1998 Conference Chair
	
	Sorin Istrail,  RECOMB 1999 Program Committee Chair 


9:00 am 		Distinguished New Technologies Lecture
Pavel Pevzner, Chair

David Cox
The Human Genetic Variation: Oligonucleotide Chips and Human Disease

10:00 am Break


Session 1,  Chair: Martin Vingron

10:10 am	Identifying Satellites in Nucleic Acid Sequences
M. Sagot, G. Meyers

10:35 am 	Genome Analysis Using Clusters of Orthologous 
		Groups (COGs)
E. Koonin, R. Tatusov, M. Y. Galperin, M. N. Rozanov  

11:00 am Break


Session 2,  Chair: Gene Myers

11:15 am  	Non-Adjoining Correlations Within Signals in DNA
P. Agarwal and V. Bafna 

11:40 am 	An Algorithm for Finding Tandem Repeats of Unspecified 
		Pattern Size
G. Benson 

12:05 pm Lunch 


1:30 pm			Invited Lecture Session 
Sorin Istrail, Chair  

Charles Cantor  
Enhancements in Sequence Analysis With DNA Arrays 

2:30 pm Break  


Session 3,  Chair: Gary Benson

2:40 pm 	Motif Discovery in Biological Sequences Without 
		Alignment or Enumeration
I. Rigoutsos, A. Floratos   

3:05 pm 	An Algorithm for Finding Novel Gapped Motifs in 
		DNA Sequences
E. Rocke, M. Tompa  

3:30 pm 	A Polyhedral Approach to RNA Sequence Structure 
		Alignment
H. Lenhof, K. Reinert, M. Vingron 

3:55 pm Break 


4:10 pm  		Stanislav Ulam Computational Biology Address 
Michael Waterman, Chair 

Joshua Lederberg 


8:00 pm-10:00 pm   	Business Meeting 
Renaissance Room 


Monday, March 23, 1998
Embassy Ballroom 

9:00 am  		Distinguished Conference Lecture 
Richard Karp, Chair 

Ron Davis 
Whole Genome Analysis: Expression, Replication, Recombination,
Allelic Variation, and Drug Discovery Function 

10:00 am Break  


Session 4,  Chair: David Searls

10:10 am 	Assessment of Ab Initio Protein Structure Prediction
A. M. Lesk 

10:35 am 	A Self-Consistent Field Optimization Approach to Build 
		Energetically and Geometrically Correct Lattice Models 
		of Proteins
B. A. Reva, A. V. Finkelstein, J. Skolnick   

11:00 am Break 


11:15 am 	Modeling DNA Shuffling
F. Sun 

11:40 am 	Multiple Genome Rearrangements
D. Sankoff, M. Blanchette  

12:05 pm Lunch  


1:30 pm  		Invited Lecture Session 
Eugene Koonin, Chair 

Ruben Abagyan 
Challenges of biomolecular structure prediction 

2:30 pm  Break 


Session 5,  Chair: Martin Farach

2:40 pm 	From Four-taxon Trees to Phylogenies: The Case 
		of Mammalian Evolution
A. Ben-Dor, B. Chor, D. Graur, R. Ophir, D. Pelleg 

3:05 pm 	On Reconstructing Species Trees From Gene Trees In Term 
		of Duplications
B. Ma, M. Li, L. Zhang  

3:30 pm 	The Ordinal Quartet Method 
P. E. Kearney 

3:55 pm Break 


4:10 pm  		Invited Lecture Session 
Bonnie Berger, Chair 

Michael Levitt 
Bridging the Gap Between Sequence and Structure 

6:00 pm-10:00 pm  Poster Session 
Renaissance Room 


Tuesday, March 24, 1998 
Embassy Ballroom 

9:00 am  		Invited Lecture Session 
Ron Shamir, Chair 

David Schwartz 
New Approaches to Genomic Analaysis Using Single Molecules 

10:00 am Break  


Session 6,  Chair: Minoru Kanehisa

10:10 am 	Algorithms for Optical Mapping
R. M. Karp, R. Shamir  

10:35 am 	Estimation for Restriction Sites Observed by Optical Mapping 
		Using Reversible-jump Markov Chain Monte Carlo
J. K. Lee, V. Dancik, M. S. Waterman 

11:00 am Break  

11:15 am 	Partitioning K Clones: Hardness Results and 
		a Practical Solution to the K-Popultaion Problem 
L. Parida, B. Mishra 

11:40 am 	Constructing Maps Using the Span and Inclusion Relations
D. Fasulo, T. Jiang, R. M. Karp, N. Sharma 

12:05 pm Lunch  


1:30 pm   		Invited Lecture Session 
Webb Miller, Chair 
 
John Yates 
Mass spectrometry and the proteome 

2:30 pm Break 


Session 7,  Chair: Thomas Lengauer

2:40 pm 	How Fast a Protein Chain Can Fold to Its Most Stable Structure?
A. V. Finkelstein, A. Ya. Badretdinov 

3:00 pm 	Algorithmic Determination of Core Positions in 
		the VL and VH Domains of Immunoglobulin Molecules
I. Gelfand, A. Kister, C. Kulikowski, O. Stoyanov 

3:30 pm 	Alignments Without Low-Scoring Regions 
Z. Zhang, P. Berman, W. Miller  

3:55 pm 	Dynamic Programmimg Alignment Accuracy
I. Holmes and R. Durbin  

4:20 pm Break  


4:30 pm  	Invited Lecture Session 
David Haussler, Chair 

Klaus Gubernator  
Evolutionary drug discovery 


Wednesday, March 25, 1998
Embassy Ballroom

Session 8, Chair: Dan Gusfield

8:30 am 	Protein Folding in the Hydrophobic-Hydrophilic (HP) Model 
		is NP-Complete
B. Berger, T. Leighton 

8:55 am 	On the Complexity of Protein Folding
P. Crescenzi, D. Goldman, C. Papadimitriou, A. Piccolboni, M. Yannakakis 

9:20 am 	A New Method for Modeling and Solving the Protein Fold 
		Recognition Problem
Y. Xu, D. Xu, E. C. Uberbacher 

9:45 am 	Optimal Detection of Sequence Similarity by Local Alignment
T. Hwa, M. Lassig 

10:10 am Break 


Session 9, Chair: Terry Speed

10:20 am 	A Formally Exact Method to Numerically Analyze Local 
		Denaturation in Superhelical DNA
R. M. Fye, C. J. Benham 

10:45 am 	The Theoretical Limits of DNA Sequence Discrimination 
		of Polyamides
W. L. Walker, D. S. Goodsell, E. M. Landaw  

11:10 am 	Maxwell Demon and Topology Simplification by 
		Type II Topoisomerases 
A. Vologodskii 

11:35 am 	A Unified Approach to Word Statistics
M. Regnier 

12:00 pm Lunch 


Session 10, Chair: Phil Green

1:00 pm 	Regression Analysis of Multiple Protein Structures 
T. D. Wu, S. C. Schmidler, T. Hastie, D. L. Brutlag 

1:25 pm 	Better Methods for Solving Parsimony and Compatiblity 
M. Bonet, M. Steel, T. Warnow, S. Yooseph 

1:50 pm 	Beyond Mutation Matrices: Physical-Chemistry Based 
		Evolutionary Models
J. M. Koshi, D. P. Mindell, R. A. Goldstein 

2:15 pm 	A Structure Based Similarity Measure for Nucleic Acid 
		Sequence Comparison
R. Liu, T. W. Blackwell and D. J. States 

2:40 pm Break 


Session 11, Chair: David Benson

2:55 pm 	The Hierarchical Organization of Molecular Structure 
		Computations 
C. C. Chen, J. P. Singh, R. B. Altman 

3:20 pm 	Estimaiton of Allele Frequencies From Color-Multiplexed 
		Electropherograms
D. G. Politte, D. R. Maffitt, D. J. States 

3:45 pm 	Analysis of the Position Dependent Amino Acid Probabilities 
		and its Applicationts to the Search for Remote Homologues
S. R. Sunyaev, I. V. Rodchenkov, F. Eisenhaber, E. N. Kuznetsov 

4:10 pm 	Family-based Homology Detection via Pairwise Sequence 
		Comparison
W. N. Grundy 
    

End of RECOMB 98









































From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!GENOME.BIOTECH.WASHINGTON.EDU!eugene
From: eugene@GENOME.BIOTECH.WASHINGTON.EDU (Eugene Kolker)
Newsgroups: bionet.software
Subject: Recomb98: Deadlines & Preliminary Program
Date: 9 Feb 1998 11:07:48 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 356
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802091906.LAA01478@genome.biotech.washington.edu>
NNTP-Posting-Host: net.bio.net


Early registration    ends  February 20, 1998!
Hotel conference rate ends  February 24, 1998!

For more details please visit our web site:
http://www.mssm.edu/biomath/recomb98.html

----------------------------------------------------------------------------

RECOMB 98 SCHEDULE

Saturday, March 21, 1998

7:00 pm - 10:00 pm	Welcome Reception 
Renaissance Room


Sunday, March 22, 1998

8:45 am  		Opening Remarks
Embassy Ballroom

	Pavel Pevzner,  RECOMB 1998 Program Committee Chair 

	Gary Benson,    RECOMB 1998 Conference Chair
	
	Sorin Istrail,  RECOMB 1999 Program Committee Chair 


9:00 am 		Distinguished New Technologies Lecture
Pavel Pevzner, Chair

David Cox
The Human Genetic Variation: Oligonucleotide Chips and Human Disease

10:00 am Break


Session 1,  Chair: Martin Vingron

10:10 am	Identifying Satellites in Nucleic Acid Sequences
M. Sagot, G. Meyers

10:35 am 	Genome Analysis Using Clusters of Orthologous 
		Groups (COGs)
E. Koonin, R. Tatusov, M. Y. Galperin, M. N. Rozanov  

11:00 am Break


Session 2,  Chair: Gene Myers

11:15 am  	Non-Adjoining Correlations Within Signals in DNA
P. Agarwal and V. Bafna 

11:40 am 	An Algorithm for Finding Tandem Repeats of Unspecified 
		Pattern Size
G. Benson 

12:05 pm Lunch 


1:30 pm			Invited Lecture Session 
Sorin Istrail, Chair  

Charles Cantor  
Enhancements in Sequence Analysis With DNA Arrays 

2:30 pm Break  


Session 3,  Chair: Gary Benson

2:40 pm 	Motif Discovery in Biological Sequences Without 
		Alignment or Enumeration
I. Rigoutsos, A. Floratos   

3:05 pm 	An Algorithm for Finding Novel Gapped Motifs in 
		DNA Sequences
E. Rocke, M. Tompa  

3:30 pm 	A Polyhedral Approach to RNA Sequence Structure 
		Alignment
H. Lenhof, K. Reinert, M. Vingron 

3:55 pm Break 


4:10 pm  		Stanislav Ulam Computational Biology Address 
Michael Waterman, Chair 

Joshua Lederberg 


8:00 pm-10:00 pm   	Business Meeting 
Renaissance Room 


Monday, March 23, 1998
Embassy Ballroom 

9:00 am  		Distinguished Conference Lecture 
Richard Karp, Chair 

Ron Davis 
Whole Genome Analysis: Expression, Replication, Recombination,
Allelic Variation, and Drug Discovery Function 

10:00 am Break  


Session 4,  Chair: David Searls

10:10 am 	Assessment of Ab Initio Protein Structure Prediction
A. M. Lesk 

10:35 am 	A Self-Consistent Field Optimization Approach to Build 
		Energetically and Geometrically Correct Lattice Models 
		of Proteins
B. A. Reva, A. V. Finkelstein, J. Skolnick   

11:00 am Break 


11:15 am 	Modeling DNA Shuffling
F. Sun 

11:40 am 	Multiple Genome Rearrangements
D. Sankoff, M. Blanchette  

12:05 pm Lunch  


1:30 pm  		Invited Lecture Session 
Eugene Koonin, Chair 

Ruben Abagyan 
Challenges of biomolecular structure prediction 

2:30 pm  Break 


Session 5,  Chair: Martin Farach

2:40 pm 	From Four-taxon Trees to Phylogenies: The Case 
		of Mammalian Evolution
A. Ben-Dor, B. Chor, D. Graur, R. Ophir, D. Pelleg 

3:05 pm 	On Reconstructing Species Trees From Gene Trees In Term 
		of Duplications
B. Ma, M. Li, L. Zhang  

3:30 pm 	The Ordinal Quartet Method 
P. E. Kearney 

3:55 pm Break 


4:10 pm  		Invited Lecture Session 
Bonnie Berger, Chair 

Michael Levitt 
Bridging the Gap Between Sequence and Structure 

6:00 pm-10:00 pm  Poster Session 
Renaissance Room 


Tuesday, March 24, 1998 
Embassy Ballroom 

9:00 am  		Invited Lecture Session 
Ron Shamir, Chair 

David Schwartz 
New Approaches to Genomic Analaysis Using Single Molecules 

10:00 am Break  


Session 6,  Chair: Minoru Kanehisa

10:10 am 	Algorithms for Optical Mapping
R. M. Karp, R. Shamir  

10:35 am 	Estimation for Restriction Sites Observed by Optical Mapping 
		Using Reversible-jump Markov Chain Monte Carlo
J. K. Lee, V. Dancik, M. S. Waterman 

11:00 am Break  

11:15 am 	Partitioning K Clones: Hardness Results and 
		a Practical Solution to the K-Popultaion Problem 
L. Parida, B. Mishra 

11:40 am 	Constructing Maps Using the Span and Inclusion Relations
D. Fasulo, T. Jiang, R. M. Karp, N. Sharma 

12:05 pm Lunch  


1:30 pm   		Invited Lecture Session 
Webb Miller, Chair 
 
John Yates 
Mass spectrometry and the proteome 

2:30 pm Break 


Session 7,  Chair: Thomas Lengauer

2:40 pm 	How Fast a Protein Chain Can Fold to Its Most Stable Structure?
A. V. Finkelstein, A. Ya. Badretdinov 

3:00 pm 	Algorithmic Determination of Core Positions in 
		the VL and VH Domains of Immunoglobulin Molecules
I. Gelfand, A. Kister, C. Kulikowski, O. Stoyanov 

3:30 pm 	Alignments Without Low-Scoring Regions 
Z. Zhang, P. Berman, W. Miller  

3:55 pm 	Dynamic Programmimg Alignment Accuracy
I. Holmes and R. Durbin  

4:20 pm Break  


4:30 pm  	Invited Lecture Session 
David Haussler, Chair 

Klaus Gubernator  
Evolutionary drug discovery 


Wednesday, March 25, 1998
Embassy Ballroom

Session 8, Chair: Dan Gusfield

8:30 am 	Protein Folding in the Hydrophobic-Hydrophilic (HP) Model 
		is NP-Complete
B. Berger, T. Leighton 

8:55 am 	On the Complexity of Protein Folding
P. Crescenzi, D. Goldman, C. Papadimitriou, A. Piccolboni, M. Yannakakis 

9:20 am 	A New Method for Modeling and Solving the Protein Fold 
		Recognition Problem
Y. Xu, D. Xu, E. C. Uberbacher 

9:45 am 	Optimal Detection of Sequence Similarity by Local Alignment
T. Hwa, M. Lassig 

10:10 am Break 


Session 9, Chair: Terry Speed

10:20 am 	A Formally Exact Method to Numerically Analyze Local 
		Denaturation in Superhelical DNA
R. M. Fye, C. J. Benham 

10:45 am 	The Theoretical Limits of DNA Sequence Discrimination 
		of Polyamides
W. L. Walker, D. S. Goodsell, E. M. Landaw  

11:10 am 	Maxwell Demon and Topology Simplification by 
		Type II Topoisomerases 
A. Vologodskii 

11:35 am 	A Unified Approach to Word Statistics
M. Regnier 

12:00 pm Lunch 


Session 10, Chair: Phil Green

1:00 pm 	Regression Analysis of Multiple Protein Structures 
T. D. Wu, S. C. Schmidler, T. Hastie, D. L. Brutlag 

1:25 pm 	Better Methods for Solving Parsimony and Compatiblity 
M. Bonet, M. Steel, T. Warnow, S. Yooseph 

1:50 pm 	Beyond Mutation Matrices: Physical-Chemistry Based 
		Evolutionary Models
J. M. Koshi, D. P. Mindell, R. A. Goldstein 

2:15 pm 	A Structure Based Similarity Measure for Nucleic Acid 
		Sequence Comparison
R. Liu, T. W. Blackwell and D. J. States 

2:40 pm Break 


Session 11, Chair: David Benson

2:55 pm 	The Hierarchical Organization of Molecular Structure 
		Computations 
C. C. Chen, J. P. Singh, R. B. Altman 

3:20 pm 	Estimaiton of Allele Frequencies From Color-Multiplexed 
		Electropherograms
D. G. Politte, D. R. Maffitt, D. J. States 

3:45 pm 	Analysis of the Position Dependent Amino Acid Probabilities 
		and its Applicationts to the Search for Remote Homologues
S. R. Sunyaev, I. V. Rodchenkov, F. Eisenhaber, E. N. Kuznetsov 

4:10 pm 	Family-based Homology Detection via Pairwise Sequence 
		Comparison
W. N. Grundy 
    

End of RECOMB 98









































From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!BORDUAS.NLM.NIH.GOV!francis
From: francis@BORDUAS.NLM.NIH.GOV (Francis Ouellette)
Newsgroups: bionet.software
Subject: Re: annotating EST sequence information with BLAST search output
Date: 8 Feb 1998 20:28:46 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 27
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802090426.XAA02664@borduas.nlm.nih.gov>
NNTP-Posting-Host: net.bio.net

> From: d.adelson@prospect.anprod.csiro.au (Dave Adelson)
> Subject: annotating EST sequence information with BLAST search output
 
> Does anyone know of a program similar to dfblast, which 
> takes the BLAST output and uses it to annotate the 
> original query sequence?  

Why would one one to annotate any record with information
which will be out of date the day it is printed?

I think we would want to discourage such annotations.

If you want to see what the record is related to, see the
blast similarity which are computed in dbEST or in the related
sequences to a record present in Entrez.  Loooking at 
annotations which will never be updated is missleading,
and uninformative.

regards,

francis

--
| B.F. Francis Ouellette  
| GenBank Coordinator
|
| francis@ncbi.nlm.nih.gov   

From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!MAIL.CYBERLINK.BG!anastas
From: anastas@MAIL.CYBERLINK.BG (Anastas Pashov)
Newsgroups: bionet.software
Subject: Reading Mac disks in PC
Date: 9 Feb 1998 15:06:40 -0800
Organization: none
Lines: 7
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <34D89294.509B@mail.cyberlink.bg>
Reply-To: anastas@mail.cyberlink.bg
NNTP-Posting-Host: net.bio.net

Hello,

Does anyone know of freeware for reading Mac disks in PC?

Thanx in advance!

Anastas Pashov

From owner-software@net.bio.net Sun Feb 08 22:00:00 1998
Path: biosci!bloom-beacon.mit.edu!news.kodak.com!news-pen-16.sprintlink.net!newsfeed.nysernet.net!news.nysernet.net!207.41.200.14!news-pen-14.sprintlink.net!206.229.87.26!news-east.sprintlink.net!news-peer.sprintlink.net!news-peer-west.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.wli.net!pln!spln!extra.newsguy.com!newsp.newsguy.com!enews1
From: No@Spam.please (Rick Thompson)
Newsgroups: bionet.software
Subject: ImageQuant for NT can it run under Win95?
Date: 9 Feb 1998 18:51:14 GMT
Organization: None
Lines: 15
Message-ID: <6bnj72$i70@enews1.newsguy.com>
NNTP-Posting-Host: p-335.newsdawg.com
X-Newsreader: WinVN 0.99.9 (Released Version) (x86 32bit)

We have a Storm PhophoImager system running imagequant software for windows NT. 
 The old version of ImageQuant for windows 3.3 will run under Win95, but is 
limited in that it does not have many of the features of the NT version.  
Especially it does not support long file names.  I'd like to know if anyone out 
there has figured out a way to get the NT version to run under Win95.  This 
would free up a logjam on the NT work station.  Unfortunately Molecular 
Dynamics simply states `it was designed to run under NT' and no one here is 
really experienced with cross platform apps.  This might be simple (e.g. copy 
a few DLLs with appropriate path statements), or it might be impossible for all 
I know.  If anyone has any experience or ideas I'd appreciate hearing them.

You can contact me directly at:

Richard.Thompson*at*uc.edu


From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!NCBI.NLM.NIH.GOV!francis
From: francis@NCBI.NLM.NIH.GOV
Newsgroups: bionet.software
Subject: Re: annotating EST sequence information with BLAST search output
Date: 9 Feb 1998 17:47:15 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 61
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199802100142.UAA06140@borduas.nlm.nih.gov>
NNTP-Posting-Host: net.bio.net


> To: bio-soft@net.bio.net
> From: Sean Eddy <eddy@wrasse.wustl.edu>
> Subject: Re: annotating EST sequence information with BLAST search output
> Date: 09 Feb 1998 07:46:31 -0600

> francis@BORDUAS.NLM.NIH.GOV (Francis Ouellette) writes:
> > Why would one one to annotate any record with information
> > which will be out of date the day it is printed?
> > 
> > I think we would want to discourage such annotations.
> 
> That's a valid point. But on the other hand, in many cases, the
> annotation is useful, and much of the information does not go out of
> date.

true ... and this is probably why it's been so popular an activity.
It's just that I'm not a great believer of automatic annotations ...

> > If you want to see what the record is related to, see the
> > blast similarity which are computed in dbEST or in the related
> > sequences to a record present in Entrez.  Loooking at 
> > annotations which will never be updated is missleading,
> > and uninformative.
> 
> That's too strong a position to take, 

yes, but it does elicit good press! :)

> I think. Scanning EST
> description lines is far, far faster than clicking through to see a
> whole dbEST record for each EST. Description lines should contain our
> "best effort" to give a short description of the EST.

yes, I agree ... it is faster, but what I question is what does it mean
when you find you have something which is similar to somothing which is
imilar to a homologue of something else?

> It's a user education problem to make sure people realize that those
> description lines are bound to be outdated, and that they may be
> misleading. But "uninformative" they're not, in my opinion.

they can be, but I agree .. the buyer must be aware ... and as a
'seller', I definitly should tell people to be careful.


**
** Be careful when reading DEFINITION lines of EST records, they can be
** informative, but they can also be misleading, and/or out of date!
**

regards to all,


francis

--
| B.F. Francis Ouellette  
| GenBank Coordinator
|
| francis@ncbi.nlm.nih.gov   

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!kyowa.co.jp!snakagawa
From: snakagawa@kyowa.co.jp (Satoshi Nakagawa)
Newsgroups: bionet.software
Subject: About MACAW
Date: 9 Feb 1998 17:41:36 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 13
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <34DFAFC4.56DF@kyowa.co.jp>
NNTP-Posting-Host: net.bio.net

Does anyone know of the MACAW that can make multiple sequence
alignments?  Can I use it on a local system?

Thanks for your help.

***********************************
Satoshi Nakagawa
snakagawa@kyowa.co.jp
Kyowa Hakko Kogyo. Co. Ltd.
Tokyo Research Laboratories
3-6-6 Asahimachi
Machida-shi Tokyo, Japan
***********************************

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news.maxwell.syr.edu!news-peer.sprintlink.net!news-backup-west.sprintlink.net!news-in-west.sprintlink.net!news.sprintlink.net!Sprint!204.97.16.5!news.monad.net!not-for-mail
From: jkeenan@top.monad.net
Newsgroups: bionet.software
Subject: Software aids project planning
Date: 10 Feb 1998 12:35:19 GMT
Organization: MonadNet
Lines: 8
Message-ID: <6bphi7$3rs$2@news.monad.net>
NNTP-Posting-Host: tcr5-75.keene.monad.net
X-Newsreader: AIR News 3.X (SPRY, Inc.)

The Amazing DOS Thought Processor supports journalling, idea
development, and no-fault thought entry. Runs on any pc.

See user's guide and download actual (four-year) example at
http://top.monad.net/~jkeenan
(click on the "retro software")
There's an order blank for this $29.95 program.


From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!Cabal.CESspool!bofh.vszbr.cz!newsfeed.eerie.fr!jussieu.fr!univ-lille1.fr!u-strasbg.fr!news
From: pingouin@chouchen.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.software
Subject: Re: DNA/Protein homology search
Date: 10 Feb 1998 09:01:39 GMT
Organization: CRC - Universite Louis Pasteur - Strasbourg France
Lines: 15
Message-ID: <6bp51j$3nb@news.u-strasbg.fr>
References: <6bmm8s$s6$1@kadri.ut.ee>
Reply-To: jeanmougin@igbmc.u-strasbg.fr
NNTP-Posting-Host: chouchen.u-strasbg.fr
Mime-Version: 1.0
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In article <6bmm8s$s6$1@kadri.ut.ee>,
	mremm@tamm.eenet.ee (Maido Remm) writes:

> 1. Query and target are DNA
> 2. Translate both sequences correctly to protein sequence
> 3. Align protein sequences
> 4. Output the same alignment as DNA sequence

	Seems to be the job of tblastx, no?

						François.

-- 
François Jeanmougin     | groupe de bioinformatique / bioinformatics groupe
tel:(+33) 3 88 65 32 71 | IGBMC BP 163 67404 Illkirch France

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news-peer.gip.net!news-raspail.gip.net!news.gsl.net!gip.net!newsfeed.eerie.fr!jussieu.fr!univ-lille1.fr!u-strasbg.fr!news
From: pingouin@chouchen.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.software
Subject: Re: annotating EST sequence information with BLAST search output
Date: 10 Feb 1998 08:58:57 GMT
Organization: CRC - Universite Louis Pasteur - Strasbourg France
Lines: 50
Message-ID: <6bp4sh$3nb@news.u-strasbg.fr>
References: <199802100142.UAA06140@borduas.nlm.nih.gov>
Reply-To: jeanmougin@igbmc.u-strasbg.fr
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Mime-Version: 1.0
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In article <199802100142.UAA06140@borduas.nlm.nih.gov>,
	francis@NCBI.NLM.NIH.GOV writes:
> 
> true ... and this is probably why it's been so popular an activity.
> It's just that I'm not a great believer of automatic annotations ...

	Sure, because, sometimes, the second record contains more
information, and only a manual annotation would be useful in this
case...

> yes, I agree ... it is faster, but what I question is what does it mean
> when you find you have something which is similar to somothing which is
> imilar to a homologue of something else?

	Yep, and what is the real information you are looking for in
an EST database? If you are looking for an homolog, you will find it
in the nr database. Looking for homologs of homologs, is, like Francis
says, quite a strange usage ;-).

	What is the real information you can find in a good EST 
database? For me :
	- Expression Pattern
	- Alternative splicing

	All the rest is quite unuseful. That's why I think that the good
way to maintain an EST database is by clustering homolog ESTs, like
STACKS do (but this implies better sequence quality or sequence cleaning).
	But probably, separatly, an expression database, a "size" or
cluster analysis one (to find full-length sequences or alternative
splicing), and whatever you would like. 

	But the current repository process is not as useful as it could be.

> **
> ** Be careful when reading DEFINITION lines of EST records, they can be
> ** informative, but they can also be misleading, and/or out of date!
> **

	Hey! stop increasing the size of the database! ;-)))). Try to
write it only with ATGCs, so we could compress it ;-).

	At least, end-user should finally stop using things 
without reading the docs...
 
					François (dreamin').
-- 
François Jeanmougin     | groupe de bioinformatique / bioinformatics groupe
tel:(+33) 3 88 65 32 71 | IGBMC BP 163 67404 Illkirch France



From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!Cabal.CESspool!bofh.vszbr.cz!newsfeed.eerie.fr!jussieu.fr!univ-lyon1.fr!news.univ-aix.fr!not-for-mail
From: Eric Blanc <eric@afmb.cnrs-mrs.fr>
Newsgroups: bionet.software
Subject: Re: Reading Mac disks in PC
Date: Tue, 10 Feb 1998 09:06:52 +0100
Organization: Universites d' Aix en Provence
Lines: 25
Message-ID: <34E00A9C.41C6@afmb.cnrs-mrs.fr>
References: <34D89294.509B@mail.cyberlink.bg>
NNTP-Posting-Host: afmb83.cnrs-mrs.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (X11; I; IRIX 5.3 IP22)

Anastas Pashov wrote:
> 
> Hello,
> 
> Does anyone know of freeware for reading Mac disks in PC?
> 
> Thanx in advance!
> 
> Anastas Pashov
I think:
Mac-ette for DOS, and tm24u under win95

-- 
------------------------------------------------------------------------------
Eric Blanc
	    Webmaster for AFMB
Email: eric@afmb.cnrs-mrs.fr
WWW:   http://afmb.cnrs-mrs.fr/~eric/
InPerson:eric@afmb83.cnrs-mrs.fr               AFMB CNRS-UPR 9039
                                                31 Ch J. Aiguier
                                                13402 Marseille CEDEX 20
                                                                       
FRANCE
Phone: 33-4-91-16-45-29
------------------------------------------------------------------------------

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news-feed.inet.tele.dk!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Heikki Lehvaslaiho <heikki@ebi.ac.uk>
Newsgroups: bionet.software
Subject: Re: Web translation utility
Date: Tue, 10 Feb 1998 13:23:18 +0000
Organization: EMBL - EBI
Lines: 22
Message-ID: <34E054C6.7EEF1D4C@ebi.ac.uk>
References: <199802051454.JAA12430@borduas.nlm.nih.gov>
NNTP-Posting-Host: cetus.ebi.ac.uk
Mime-Version: 1.0
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X-Mailer: Mozilla 4.03 [en] (X11; I; IRIX64 6.2 IP28)

francis@NCBI.NLM.NIH.GOV wrote:
> 
> > From BIOSCI-REQUEST@net.bio.net Thu Feb  5 09:42:05 1998
> 
> > Could someone point me to a web translation utility? I simply want to input a
> > DNA sequence and (after defining the reading frame), get back the peptide
> > sequence. Does NCBI have a utility like this?
> >
> > Answer by email, please sjhogart@unity.ncsu.edu


Also, you could have a look at http://www2.ebi.ac.uk/translate/

	-Heikki
______ _/      _/_____________________________________________________
      _/      _/                      http://www2.ebi.ac.uk/mutations/
     _/  _/  _/  Heikki Lehvaslaiho          heikki@ebi.ac.uk
    _/_/_/_/_/  EMBL Outstation, European Bioinformatics Institute
   _/  _/  _/  Wellcome Trust Genome Campus, Hinxton
  _/  _/  _/  Cambs. CB10 1SD, United Kingdom
     _/      Phone: +44 (0)1223 494 644   FAX: +44 (0)1223 494 468
___ _/_/_/_/_/________________________________________________________

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!howland.erols.net!newsfeed.direct.ca!Supernews60!supernews.com!uunet!in2.uu.net!news.pyramid.com!whowhere.com!nntp.csuchico.edu!waldorf.csc.calpoly.edu!nntp-server.caltech.edu!seqaxp.bio.caltech.edu!MATHOG
From: mathog@seqaxp.bio.caltech.edu
Newsgroups: bionet.software
Subject: Re: Helix-Turn-Helix
Date: 9 Feb 1998 17:50:33 GMT
Organization: Biology Division, Caltech, Pasadena CA 91125
Lines: 19
Message-ID: <6bnfl9$m4a@gap.cco.caltech.edu>
References: <34DDFA48.27A1@student.canterbury.ac.nz>
Reply-To: mathog@seqaxp.bio.caltech.edu
NNTP-Posting-Host: seqaxp.bio.caltech.edu

In article <34DDFA48.27A1@student.canterbury.ac.nz>, Mark Silby <mws33@student.canterbury.ac.nz> writes:
>Hi all
>
>I am investigating a putative DNA binding protein, and am interested in
>aquiring a program that can be used to predict helix-turn-helix motifs
>based upon the predicted protein sequence.  Any suggestions of shareware
>or commercial programs would be appreciated.
>

The EGCG package contains a program HELIXTURNHELIX which may do what you 
want.  Many sites that have GCG also have EGCG installed.  The closest site
that I know of to you is ANGUS, but probably somebody in NZ has these
programs installed - ask around.

Regards,

David Mathog
mathog@seqaxp.bio.caltech.edu
Manager, sequence analysis facility, biology division, Caltech 

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!howland.erols.net!news-feed.inet.tele.dk!bofh.vszbr.cz!masternews.telia.net!news-stkh.gip.net!news.gsl.net!gip.net!news.kolumbus.fi!news.uninet.ee!kadri.ut.ee!tamm!mremm
From: mremm@tamm.eenet.ee (Maido Remm)
Newsgroups: bionet.software
Subject: DNA/Protein homology search
Date: 9 Feb 1998 10:37:16 GMT
Organization: Estonian Biocentre
Lines: 18
Message-ID: <6bmm8s$s6$1@kadri.ut.ee>
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Hei,

Has anybody written script or program to align gene DNA sequences according
to their protein sequence: I mean it should do the following

1. Query and target are DNA
2. Translate both sequences correctly to protein sequence
3. Align protein sequences
4. Output the same alignment as DNA sequence

I would name it codon alignment. It should have much more sense than
straigth comparision of DNA. I have been told that similar program have
announced here recently, but i was unable to find something like that in
archives. 

Thanks for your time,
Maido Remm
Estonian Biocentre. 

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
Path: biosci!agate!newsgate.duke.edu!news-relay.ncren.net!ussun2n!news@ussun2n.glaxo.com
From: "Gary H. Merrill" <ghm48805@glaxowellcome.com>
Newsgroups: sci.med.informatics,comp.ai,comp.ia.nat-lang,bionet.software
Subject: 2nd CFP:  AAAI-98 Wkshp on Knowledge Sharing Across Bio and Med KB Systems
Date: Tue, 10 Feb 1998 15:43:08 -0500
Organization: GlaxoWellcome Inc
Lines: 125
Message-ID: <34E0BBDC.3F4D@glaxowellcome.com>
Reply-To: ghm48805@glaxowellcome.com
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CC: dp33010@glaxowellcome.com, bean@nlm.nih.gov,
	abrass@manchester.ac.uk, hammo001@mc.duke.edu,
	jenders@cucis.cis.columbia.edu

In addition to soliciting submissions from potential presenters, we
encourage others interested in attending and taking part in the
discussions to send a brief letter indicating their desire to attend. 
Please note that the deadline for submissions is March 11.

==============



TITLE



  AAAI-98 Workshop on KNOWLEDGE SHARING ACROSS BIOLOGICAL AND MEDICAL
KNOWLEDGE BASED SYSTEMS



DATE AND LOCATION



   National Conference on Artificial Intelligence (AAAI-98) in Madison,
Wisconsin, July 26 - July 27, 1998.  See the AAAI web site at
http://www.aaai.org for additional details.

 

DESCRIPTION



The amount of biological and medical information is growing at an
exponential rate and overwhelming researchers and clinicians. Various
groups have applied the technology of knowledge base systems to help in
the effective utilization of available information.  These systems have
been used for applications in information retrieval, natural language
processing, database integration, machine earning, data mining, and
decision-making. 



While there is a substantial overlap of knowledge represented in these
knowledge based systems there has been very limited dialog among the
various groups creating these systems. This one-day workshop explores
ways in which the knowledge contained in the various systems can be
shared. 



Specifically, the workshop goals include:



1. Understanding the scope of knowledge contained in various knowledge
based systems in biology and medicine.



2. Understanding strengths and limitations of different knowledge
representation formalisms, inference engines, and knowledge acquisition
methods for biological and medical systems.



3. Identifying strategies for knowledge sharing across different
development groups as we move toward more comprehensive knowledge bases
for researchers and clinicians in biology and medicine.





SUBMISSIONS



Potential presenters should submit a short paper (up to 5-8 pages)
addressing any of the issues relevant to the workshop goals.  Others
interested in participating should submit a 1-2 page statement of
background and interest.  



E-mail in PostScript or MS Word format to



        Dhiraj K. Pathak at dp33010@glaxowellcome.com
or
        Gary H. Merrill at ghm48805@glaxowellcome.com 



Submission Deadline:  March 11, 1998



Notification Date:  April 1, 1998




ORGANIZING COMMITTEE



Dhiraj K. Pathak, Glaxo Wellcome (Co-chair) (dp33010@glaxowellcome.com)

Gary H. Merrill, Glaxo Wellcome (Co-chair) (ghm48805@glaxowellcome.com)

Carol Bean, National Library of Medicine (bean@nlm.nih.gov)

Andy Brass, University of Manchester (abrass@manchester.ac.uk)

Ed Hammond, Duke University (hammo001@mc.duke.edu)

Rober Jenders, Columbia University (jenders@cucis.cis.columbia.edu)


-- 

Gary H. Merrill / Principal Consultant, Information Access Technology
[Views and opinions expressed here are my own and not necessarily
those of GlaxoWellcome Inc.]

From owner-software@net.bio.net Mon Feb 09 22:00:00 1998
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From: Burkhard Morgenstern <morgenst@gsf.de>
Newsgroups: bionet.software
Subject: Re: DNA/Protein homology search
Date: Tue, 10 Feb 1998 09:38:43 -0500
Organization: North Carolina State University
Lines: 34
Message-ID: <34E06673.4A9F@gsf.de>
References: <6bmm8s$s6$1@kadri.ut.ee>
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Maido Remm wrote:
> 
> Hei,
> 
> Has anybody written script or program to align gene DNA sequences according
> to their protein sequence: I mean it should do the following
> 
> 1. Query and target are DNA
> 2. Translate both sequences correctly to protein sequence
> 3. Align protein sequences
> 4. Output the same alignment as DNA sequence
> 
> I would name it codon alignment. It should have much more sense than
> straigth comparision of DNA. I have been told that similar program have
> announced here recently, but i was unable to find something like that in
> archives.
> 
> Thanks for your time,
> Maido Remm
> Estonian Biocentre.

Hello,

I have written an alignment program that does exactly
what you are looking for. It is called DIALIGN. 

Executables for various UNIX platforms (including LINUX)
are available at

  http://www.gsf.de/biodv/dialign.html

Hope this helps

  Burkhard Morgenstern

From owner-software@net.bio.net Tue Feb 10 22:00:00 1998
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!152.163.199.19!portc03.blue.aol.com!audrey02.news.aol.com!not-for-mail
From: legalsuite@aol.com (LEGALSUITE)
Newsgroups: bionet.software
Subject: URGENT MESSAGE FOR USERS OF COREL SOFTWARE
Date: 11 Feb 1998 18:58:33 GMT
Lines: 20
Message-ID: <19980211185800.NAA24220@ladder02.news.aol.com>
NNTP-Posting-Host: ladder02.news.aol.com
X-Admin: news@aol.com
Organization: AOL http://www.aol.com

Have you been lied to or deceived by Corel's technical team? Have they
knowingly sold you the wrong software (Paradox 8) causing you to waste
valueable time and money?

Did you hire Corel's technical team to do a specific project for you and found
that the finished product was defective or deceivingly incomplete? Did they
complete you project months after the due date, or after months of being late,
did they tell you that they did not have the technology to do your project at
all,
Or did they say that your project was complete when they had not even started
the project that you hired them to do?

Has Corel's technical team damaged your business or created great financial
loss to your business?

If you can prove any of the above statements and you are interested in joining
a class action suite against Corel Corporation, contact me. Include a detailed
description of your circumstances.

LAWSUITE@aol.com

From owner-software@net.bio.net Tue Feb 10 22:00:00 1998
From: classads@bigfoot.com (cda)
Newsgroups: bionet.software
Subject: need help.....
Date: Wed, 11 Feb 1998 14:45:50 GMT
Reply-To: classads@bigfoot.com
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I am finding a real-life example in which the software development
project was completes throught the use of prototyping. This is for my
assignment, and I am having difficulties in finding such info over the
net, so I've think of getting help from the usenet, from you people
out there.
Please send me the info , like URL where to find the information, your
email address(to get contact with u). If you have experience this
process yourself, please write to me the story including the following
areas:
- description of the software, its nature and application area;
- a brieft write-up on the prototyping methodology of development;
- why the prototyping method is particulaly suitable for the
development of this software;
- how the software was acctually developed using this methodology.

From owner-software@net.bio.net Tue Feb 10 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!news.maxwell.syr.edu!news-ge.switch.ch!iol!not-for-mail
From: coupers@iol.ie (The Coupers)
Newsgroups: bionet.software
Subject: Text Comparison/ Version  Software
Date: Wed, 11 Feb 1998 22:42:56 GMT
Organization: Ireland On-Line
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X-Newsreader: Forte Free Agent 1.11/16.235

Hi

Does anyone know of a program for comparing different version of a
text report and highlighting differences?  I saw something years ago
but can't remeber where.

Thanks

David Couper

From owner-software@net.bio.net Tue Feb 10 22:00:00 1998
Date: Wed, 11 Feb 1998 21:43:16 +0100
From: gerard@xray.bmc.uu.se (Gerard Kleywegt)
Newsgroups: sci.med.informatics,comp.ai,comp.ia.nat-lang,bionet.software
Subject: Re: 2nd CFP:  AAAI-98 Wkshp on Knowledge Sharing Across Bio and Med KB Systems
Message-ID: <gerard-1102982143160001@nostromo.bmc.uu.se>
References: <34E0BBDC.3F4D@glaxowellcome.com>
Organization: SBNet - Uppsala University
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In article <34E0BBDC.3F4D@glaxowellcome.com>, ghm48805@glaxowellcome.com wrote:

>The amount of biological and medical information is growing at an
>exponential rate and overwhelming researchers and clinicians. Various
>groups have applied the technology of knowledge base systems to help in
>the effective utilization of available information.  These systems have
>been used for applications in information retrieval, natural language
>processing, database integration, machine earning, data mining, and
                                   ***************
>decision-making. 

"machine earning" - you mean computers that wash cars
at trafic lights ?  or is this about automatic spam
generators of the 'get rich quick' ilk ???

--cd
----------------------------------------------------------
Gerard Kleywegt
mailto:gerard@xray.bmc.uu.se
http://alpha2.bmc.uu.se/~gerard/

From owner-software@net.bio.net Tue Feb 10 22:00:00 1998
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From: "Joe Wang" <cwang@scu.edu>
Newsgroups: bionet.software
Subject: A test
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