From owner-software@net.bio.net Thu Jul 01 00:36:00 1999
Path: biosci!PRIDNS.SCU.EDU.CN!scunlgbc
From: scunlgbc@PRIDNS.SCU.EDU.CN ("afei")
Newsgroups: bionet.software
Subject: Request for free DNA sequence analysis software
Date: 30 Jun 1999 18:36:07 -0700
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Dear colleagues,

 I am a PhD student in China.I have sequenced some genes I isolated.But I
don't have any analysis software on hand,so I can't analysize the
sequences.If someone can give me this kind of software,I will be very
appriciate of it.

Yours Sincerely,
Shen Bin

(Please email me shenbin73@263.net)


From owner-software@net.bio.net Thu Jul 01 01:09:00 1999
Path: biosci!SUNM.SHCNC.AC.CN!xietao
From: xietao@SUNM.SHCNC.AC.CN (xietao)
Newsgroups: bionet.software
Subject: Re: Request for free DNA sequence analysis software
Date: 30 Jun 1999 19:09:11 -0700
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Hi, "afei",



in 99-6-30 18:36:00 £º
>Dear colleagues,
>
> I am a PhD student in China.I have sequenced some 
genes I isolated.But I
>don't have any analysis software on hand,so I can't 
analysize the
>sequences.If someone can give me this kind of 
software,I will be very
>appriciate of it.
>
>Yours Sincerely,
>Shen Bin
>
>(Please email me shenbin73@263.net)

Please visit our institute's homepage:
http://dna.sibc.ac.cn/bio/index.htm

BTW, where are you?

Tao, Xie 
Shang Institute of Biochemistry




From owner-software@net.bio.net Thu Jul 01 06:39:00 1999
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From: "Marcel Dinger" <marcel@genamics.com>
Newsgroups: bionet.software
Subject: Genamics - SoftwareSeek
Date: Thu, 1 Jul 1999 19:27:59 +1200
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Genamics SoftwareSeek and other molecular resources at http://genamics.com
just got better:

With over 650 software entries, 360 journal speed links, and 100+ genome
project links, you can be assured that you can find what you need, and find
it quickly.

1. SoftwareSeek - The largest collection of software tools available for
Windows, MS-DOS, Unix, Linux and Macintosh platforms.  Entries are classifed
into several categories, including DNA sequence analysis, protein structure
analysis, RNA structure prediction, molecular modeling, image analysis, and
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2. GenomeSeek - A searchable database of current information about microbial
genome projects with links to relevant sites and publications. The database
contains
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Marcel Dinger,
Genamics.




From owner-software@net.bio.net Thu Jul 01 07:43:00 1999
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From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software
Subject: Re: Request for free DNA sequence analysis software
Date: 01 Jul 1999 09:37:06 +0100
Organization: The Sanger Centre
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scunlgbc@PRIDNS.SCU.EDU.CN ("afei") writes:
>  I am a PhD student in China.I have sequenced some genes I isolated.But I
> don't have any analysis software on hand,so I can't analysize the
> sequences.If someone can give me this kind of software,I will be very
> appriciate of it.

I am developing a free sequence analysis package called EMBOSS
(European Molecular Biology Open Software Suite) which runs on all
common Unix systems.

EMBOSS is a collaboration with members of EMBnet, including the Chinese
national node at Peking University.

The EMBOSS project web pages are at http://www.sanger.ac.uk/Software/EMBOSS/

There is an alpha release (changing daily) on our FTP server.

First beta release is due as soon as the command line sytax is stable.

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-software@net.bio.net Thu Jul 01 07:46:00 1999
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From: bortzmeyer@pasteur.fr (Stephane Bortzmeyer)
Newsgroups: bionet.software
Subject: Re: Request for free DNA sequence analysis software
Date: 1 Jul 1999 08:40:54 GMT
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In article <000101bec361$28880740$823373ca@afei.scu.edu.cn>,
 scunlgbc@PRIDNS.SCU.EDU.CN ("afei") writes:

>  I am a PhD student in China.I have sequenced some genes I isolated.But I
> don't have any analysis software on hand,so I can't analysize the
> sequences.

"free" in English is ambiguous. Do you refer to freedom or to price?

For "free as in free speech" software, there are several sources, it 
depends on your platform. For instance, if you use Debian/GNU Linux:

http://www.pasteur.fr/units/sis/debian/biology-en.html

You'll find Blast, Seaview, and their friends.

If you run another brand of Linux:

http://evolution.bmc.uu.se/~thomas/mol_linux/
http://www.llp.fu-berlin.de/lsoft/Z/2/

etc.

From owner-software@net.bio.net Thu Jul 01 11:10:00 1999
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From: Rasmus Paetau <rpaetau@nospam.helsinki.fi>
Newsgroups: bionet.software
Subject: Free plasmid drawing software for Mac?
Date: 1 Jul 1999 14:50:09 +0300
Organization: University of Helsinki
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Is there any good plasmid drawing software that is free for Macintoshes?
MacPlasmap and Plasmid artist are giving me trouble...

Thanks in advance,
	Rasmus Paetau

(If you reply via email, remove nospam from the address)

-- 
|| E-mail: rpaetau@cc.helsinki.fi     || University of Helsinki ||
||    WWW: http://www.hut.fi/~rpaetau ||  Faculty of Medicine   ||

From owner-software@net.bio.net Thu Jul 01 14:48:00 1999
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From: merrydoc@yeamob.pci.chemie.uni-tuebingen.de (MerryDoc)
Newsgroups: bionet.software
Subject: Re: Free plasmid drawing software for Mac?
Date: Thu, 01 Jul 1999 17:42:23 +0200
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In article <7lfklh$r8k@vesuri.Helsinki.FI>, Rasmus Paetau
<rpaetau@nospam.helsinki.fi> wrote:

> Is there any good plasmid drawing software that is free for Macintoshes?
> MacPlasmap and Plasmid artist are giving me trouble...
> 
> Thanks in advance,
>         Rasmus Paetau

Hi Rasmus,

I have written a plasmid drawing program for the Macintosh which I 
have released as Freeware. It allows to draw circular or linear maps. 
It was originally intended for our lab use, so it is anything but polished. 
It converts lists of restriction sites and fragment/gene positions into 
Postscript files.

Its weak points in short
- It is a Hypercard stack, so you need Hypercard to run it (luckily, speed
is no problem, there are no processor intensive steps involved)
- The output are Postscript files in Illustrator format. To view and to
further edit the picture (which you will have to, see below), you need
either Adobe Illustrator, or the Shareware EPStoPICT, which produces a
fully editable, object oriented PICT version of the graphics.
- The program does not care for overlapping labels, so in most cases you
must do some fine-tuning 

On the other hand, the program
- allows "electronic cloning", so you can quickly construct new plasmids
from those already entered in the program
- can draw all plasmids at the same size, but also using the same (or any
you want) scale (that was the primary reason for me to write the program,
most commercial programs  had (still have?) no way to specify the drawing
scale (except by different magnification in the page setup)
- draws linear and circular maps, allows borders of various widths and
fills of grays, arrows...
- Output quality is great, thanks to Postscript
- The price is right

For a more detailed description, including screen shots of the output
graphics,  see
<http://yeamob.pci.chemie.uni-tuebingen.de/Archiv/PlasmidMaker.html>

and that is also the place to download the stack:
<http://yeamob.pci.chemie.uni-tuebingen.de/Archiv/Plasmid-Maker.hqx>

(BTW, there is also a stack for the organization of plasmid/strain
collections available)

Kai
-----------------------------------------------------------------------
Dr. Kai-Uwe Fröhlich, Physiologisch-chemisches Institut, 
Hoppe-Seyler-Str. 4, 76072 Tübingen, Germany

From owner-software@net.bio.net Thu Jul 01 17:40:00 1999
Path: biosci!newshost.lanl.gov!logbridge.uoregon.edu!newspeer.monmouth.com!remarQ-easT!supernews.com!remarQ.com!attmtf!attmt1!ip.att.net!news.merck.com!internal.merck.com
From: mark_yeager@merck.com (Mark Yeager)
Newsgroups: bionet.software
Subject: Re: Free plasmid drawing software for Mac?
Date: Thu, 01 Jul 1999 14:31:17 -0400
Organization: Merck Research Labs
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References: <7lfklh$r8k@vesuri.Helsinki.FI>
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In article <7lfklh$r8k@vesuri.Helsinki.FI>, Rasmus Paetau <rpaetau@nospam.helsinki.fi> wrote:

> Is there any good plasmid drawing software that is free for Macintoshes?
> MacPlasmap and Plasmid artist are giving me trouble...

Try the free Vector NTI viewer:

http://informaxinc.com/view/viewer.html

Just construct your plasmid as a Genbank formatted text file (see examples) and voila!


       The contents of this message express only the sender's opinion.
       This message does not necessarily reflect the policy or views of
       my employer, Merck & Co., Inc.  All responsibility for the statements
       made in this Usenet posting resides solely and completely with the
       sender.

From owner-software@net.bio.net Thu Jul 01 21:01:00 1999
Path: biosci!BLA-BLA.COM!ashleyf
From: ashleyf@BLA-BLA.COM ("Marcus")
Newsgroups: bionet.software
Subject: Oh, You Didn't Know
Date: 1 Jul 1999 15:01:10 -0700
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From owner-software@net.bio.net Fri Jul 02 07:00:00 1999
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From owner-software@net.bio.net Fri Jul 02 07:01:00 1999
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From: pujadas@argo.urv.es (Gerard Pujadas)
Newsgroups: bionet.software
Subject: DNASTAR ---> FASTA format for Macintosh
Date: 2 Jul 1999 08:55:10 +0100
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	Dear all,

	I would like to find a Macintosh software that allow to convert
more than a hundred of protein sequences files in DNASTAR format into their
equivalent FASTA format files. It could be preferred that the application
support drag-and-drop use.

	Thanks in advances for your help.

	Yours sincerely.

	Gerard.

===========================================================================
DR. GERARD PUJADAS
BIOTECNOLOGIA COMPUTACIONAL
DEPT. BIOQUIMICA I BIOTECNOLOGIA	   E-MAIL: pujadas@quimica.urv.es
UNIV. ROVIRA I VIRGILI                     PHONE: 34-977 559565
PLAÇA IMPERIAL TARRACO 1                   FAX: 34-977 559597
43005 TARRAGONA (CATALONIA)
STATE: SPAIN (EUROPEAN UNION)
===========================================================================


---

From owner-software@net.bio.net Fri Jul 02 22:24:00 1999
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From: john_q_barlow@hotmail.com (John Barlow)
Newsgroups: bionet.software
Subject: Re: DNASTAR ---> FASTA format for Macintosh
Date: 2 Jul 1999 22:31:12 GMT
Organization: MindSpring Enterprises
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In article <v03102700b3a22e18487a@[130.206.36.86]>, pujadas@argo.urv.es says...
Hi Gerard:
I do not know if an application of this kind exists for the Mac,
however, if you do not mind transferring files from Mac to PC, you
can use SeqVerter for Windows to do exactly this task.  It is
drag-and-drop and will batch process all the files.
SeqVerter is free and can be downloaded  from:
http://www.genestudio.com.

Cheers!
John

>
>
>        Dear all,
>
>        I would like to find a Macintosh software that allow to convert
>more than a hundred of protein sequences files in DNASTAR format into their
>equivalent FASTA format files. It could be preferred that the application
>support drag-and-drop use.
>
>        Thanks in advances for your help.
>
>        Yours sincerely.
>
>        Gerard.
>
>===========================================================================
>DR. GERARD PUJADAS
>BIOTECNOLOGIA COMPUTACIONAL
>DEPT. BIOQUIMICA I BIOTECNOLOGIA           E-MAIL: pujadas@quimica.urv.es
>UNIV. ROVIRA I VIRGILI                     PHONE: 34-977 559565
>PLAÇA IMPERIAL TARRACO 1                   FAX: 34-977 559597
>43005 TARRAGONA (CATALONIA)
>STATE: SPAIN (EUROPEAN UNION)
>===========================================================================
>
>
>---


From owner-software@net.bio.net Sat Jul 03 11:25:00 1999
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From: mboo@seqnet.dl.ac.uk
Newsgroups: bionet.software
Subject: Compiling Namot for Linux
Date: Sat, 03 Jul 1999 12:09:57 GMT
Organization: Deja.com - Share what you know. Learn what you don't.
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Hi

I recently obtained Namot from LANL's ftp server.  It compiles without
problems after adding -L/usr/X11R6/lib (holds the libX11.a file) but It
crashes when I sattempt to  type text into any dialogue box.  I've
re-installed the xview and openwin libs and binaries on my system but it
hasn't helped.

Any clues?

Dayo


Sent via Deja.com http://www.deja.com/
Share what you know. Learn what you don't.

From owner-software@net.bio.net Sat Jul 03 19:50:00 1999
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From: "Hilton Evans" <hfevans_NOSPAM@ici.net>
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Chempen Chemical Structure Drawing  -- http://home.ici.net/~hfevans/chempen.htm
ChemPen3D Molecular Mechanics  for Win95/NT --  http://home.ici.net/~hfevans/chempen3d.htm

-- 
Hilton Evans
Organic Reactions  -- http://home.ici.net/~hfevans/reactions.htm
Coming Summer 1999 -- NMR Shifts Prediction


From owner-software@net.bio.net Sat Jul 03 23:40:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!agate!usenet
From: Michael Schmitz <MSchmitz@lbl.gov>
Newsgroups: bionet.software
Subject: Re: Compiling Namot for Linux
Date: Sat, 03 Jul 1999 17:34:41 -0700
Organization: Tinoco Lab, UC Berkekely / Lawrence Berkeley Laboratory
Lines: 13
Message-ID: <377EAC21.B907E991@lbl.gov>
References: <7lkuii$5hd$1@nnrp1.deja.com>
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mboo@seqnet.dl.ac.uk wrote:
> I recently obtained Namot from LANL's ftp server.  It compiles without
> problems after adding -L/usr/X11R6/lib (holds the libX11.a file) but It
> crashes when I sattempt to  type text into any dialogue box.  I've
> re-installed the xview and openwin libs and binaries on my system but it
> hasn't helped.
> 
> Any clues?

What versions of libc, libX11 etc. does this happen with? Last time I
built it there were no problems, but that's been a while ago...

	Michael

From owner-software@net.bio.net Sun Jul 04 11:12:00 1999
From: "Ò²¨K¥S" <vicentc@hotmail.com>
Newsgroups: bionet.software
Subject: ½Ö¤H¦³Real audio G3 ªº¤U¸üsite©O? ­ø¸Ó«{!!
Date: Sat, 3 Jul 1999 19:46:34 +0800
Organization: Hongkong Baptist University
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Path: biosci!news.stanford.edu!newsfeed.stanford.edu!news-feed.inet.tele.dk!bofh.vszbr.cz!uninett.no!newsfeed.nacamar.de!newsfeed.nacamar.de!f.de.uu.net!do.de.uu.net!uunet!ams.uu.net!ffx.uu.net!in5.uu.net!news-hk.telia.net!d2o501.telia.com!newsgate.cuhk.edu.hk!power25t.hkbu.edu.hk!not-for-mail

½Ö¤H¦³Real audio G3 ªº¤U¸üsite©O? ­ø¸Ó«{!!



From owner-software@net.bio.net Sun Jul 04 16:32:00 1999
Path: biosci!agate!newsfeed.berkeley.edu!howland.erols.net!portc02.blue.aol.com!audrey03.news.aol.com!not-for-mail
From: ksookoo@aol.com (KSookoo)
Newsgroups: bionet.software
Subject: RN Exam Softare?  Got any?
Lines: 2
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Interested in software for assistance in the Registered Nurse Exam.  Can anyone
help? 

From owner-software@net.bio.net Sun Jul 04 19:22:00 1999
Path: biosci!USA.NET!netware33
From: netware33@USA.NET
Newsgroups: bionet.software
Subject: ADV:
Date: 4 Jul 1999 13:22:43 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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**************************************************
This is a one time mailing, no need to be removed.
**************************************************

FLAT RATE LONG DISTANCE IS NOW ACTIVE AND AVAIALBLE FOR U.S.
PEOPLE TO USE NOW!

MAJOR ANNOUNCEMENT:
No matter if you're a business or simply a normal user, you can now have a
predictable, flat rate monthly long distance bil and save up to 80% of what
you now pay...AND, as an option, you can tell yor friends about this highly
desirable service and generate $10,000 a year from home...and now so will you!

WHAT IT COSTS:
Based on your first months' usage, you will have a flat rate "tier service"
of either $60, $80, $100 (which includes calls into Canada), or a maximum
of $160 per month (this tier is for users that average $500 or more).
There is a ONE TIME set up of $50 (which also gives you a website to use to
sign up people...there are no other fees)!

This is the greatest and simplest opportunity of all time PLUS, it allows
us to call long distance without "watching the clock" AND, you don't need
to switch carriers (if you don't use long distance, how many people do you
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commissionable...to get details, contact us IMMEDIATELY toll free at
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we'll get back to you using the service, with complete details!

Whether you just want to use the service and save money, or make a
substantial monthly income by teling others or both...TAKE ACTION NOW
before someone you could have signed up, comes to you with this one f a
kind opportunity!

THIS OFFER HAS NOTHING TO DO WITH COMPANIES NAMED; T.C.I., I-LINK,
TRENDMARK, OR USA TALKS...our is the ONLY service that is now active
throughout the US ow (and soon to be available in Canada)!!


We haven't spoken in a while, so if this reached you by mistake, OR if
youdon't need flat rate long distance, we apologize! 

 
 
 
 
 

From owner-software@net.bio.net Mon Jul 05 07:24:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!news-peer.gip.net!news.gsl.net!gip.net!spring.edu.tw!netnews.hinet.net!news
From: dreamcast023@ms1.tomail.com.tw
Newsgroups: bionet.software
Subject: ³Ìªñ±`³QÀb«È¿NÂZ¶Ü?³Ì·s¨¾ªvÀb«È¥úºÐ!!
Date: 5 Jul 1999 08:18:34 GMT
Organization: dreamcast023
Lines: 187
Message-ID: <7lppoq$6d7@netnews.hinet.net>
NNTP-Posting-Host: h21.s151.ts31.hinet.net

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       ½Ð¦^«H¦Ü  dreamcast023@ms1.tomail.com.tw


From owner-software@net.bio.net Mon Jul 05 08:21:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!dispose.news.demon.net!demon!colt.net!news0.de.colt.net!news-fra1.dfn.de!news-ber1.dfn.de!zrz.TU-Berlin.DE!not-for-mail
From: Henrik Seidel <Henrik.Seidel@gmx.de>
Newsgroups: bionet.software
Subject: Compiling treetool for Linux - any success?
Date: 5 Jul 1999 09:15:17 GMT
Organization: Technical University Berlin, Germany
Distribution: world
Message-ID: <7lpt35$r00$4@mamenchi.zrz.TU-Berlin.DE>
NNTP-Posting-Host: dns1.schering.de
Mime-Version: 1.0
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X-Newsreader: knews 1.0b.0
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Did anybody succeed in compiling treetool on a Linux machine? Or does
anybody know a Unix or Java tool comparable to Win*s TreeView?

Thanks for any help.
				--- Henrik Seidel

From owner-software@net.bio.net Mon Jul 05 09:11:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!easynet-fr!ciril.fr!news.u-strasbg.fr!not-for-mail
From: pingouin@crystal.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.software
Subject: Re: Compiling treetool for Linux - any success?
Date: 5 Jul 1999 11:07:25 GMT
Organization: CRC - Universite Louis Pasteur Strasbourg France
Lines: 19
Message-ID: <7lq3ld$7fb$1@news.u-strasbg.fr>
References: <7lpt35$r00$4@mamenchi.zrz.TU-Berlin.DE>
Reply-To: jeanmougin@igbmc.u-strasbg.fr
NNTP-Posting-Host: crystal.u-strasbg.fr
Mime-Version: 1.0
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In article <7lpt35$r00$4@mamenchi.zrz.tu-berlin.de>,
	Henrik Seidel <Henrik.Seidel@gmx.de> writes:
> Did anybody succeed in compiling treetool on a Linux machine? Or does
> anybody know a Unix or Java tool comparable to Win*s TreeView?

	Treetool has 2 problems : Xview libraries and support for 
8 bits displays only. You'd better use njplot. njplot can be found as
a debian package from :

http://www.pasteur.fr/units/sis/debian/biology.html

And probably as RPM packages from :

http://rpmfind.net/linux/RPM/Applications_Bioinformatics.html

						François.
-- 
François Jeanmougin     | groupe de bioinformatique / bioinformatics groupe
tel:(+33) 3 88 65 32 71 | IGBMC BP 163 67404 Illkirch France

From owner-software@net.bio.net Mon Jul 05 10:00:00 1999
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From: bortzmeyer@pasteur.fr (Stephane Bortzmeyer)
Newsgroups: bionet.software
Subject: Re: Compiling treetool for Linux - any success?
Date: 5 Jul 1999 10:54:05 GMT
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In article <7lq3ld$7fb$1@news.u-strasbg.fr>,
 pingouin@crystal.u-strasbg.fr (Francois Jeanmougin) writes:

> 	Treetool has 2 problems : Xview libraries and support for 
> 8 bits displays only. 

Yes, they are problems, but they have solutions. Treetool runs fine
on my Linux box with 16-bits display.

> You'd better use njplot. njplot can be found as
> a debian package from :
> 
> http://www.pasteur.fr/units/sis/debian/biology.html

The Debian package of treetool is at the same place :-)
 
> And probably as RPM packages from :
> 
> http://rpmfind.net/linux/RPM/Applications_Bioinformatics.html

No. The above is really poor (they just have Blast), probably because 
serious work is one on Debian only :-)



From owner-software@net.bio.net Mon Jul 05 12:33:00 1999
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From: Henrik Seidel <Henrik.Seidel@gmx.de>
Newsgroups: bionet.software
Subject: Re: Compiling treetool for Linux - any success?
Date: 5 Jul 1999 13:27:12 GMT
Organization: Technical University Berlin, Germany
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In article <7lq2sd$ouh$1@desdemone.pasteur.fr>,
	bortzmeyer@pasteur.fr (Stephane Bortzmeyer) writes:

>> And probably as RPM packages from :
>> 
>> http://rpmfind.net/linux/RPM/Applications_Bioinformatics.html
> 
> No. The above is really poor (they just have Blast), probably because 
> serious work is one on Debian only :-)

I don't want to comment on that, but I prepared RPMs based on Stephane's
Debian package. They can be found at

  http://www.snafu.de/~henrik.seidel/

Thanks for your help.
				--- Henrik Seidel

From owner-software@net.bio.net Mon Jul 05 12:48:00 1999
Path: biosci!SIRIUS.GAZI.EDU.TR!alevd
From: alevd@SIRIUS.GAZI.EDU.TR ("Ars.Alev DOGAN")
Newsgroups: bionet.software
Subject: superquad
Date: 5 Jul 1999 06:48:13 -0700
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Message-ID: <Pine.LNX.4.10.9907051641180.16386-100000@sirius.gazi.edu.tr>
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Dear Sir,
I am a Ph.D. student and a researc assistant in chemistry Department of
Gazi Universitiy,Ankara-Turkey.I am interested in potentiometric
measurements of some amino acids.I want to get more detailed about the
program SUPERQUAD, appreciate if you can help me to buy a copy of it.
Thank you in advance for your kind attention.
Sincerely yours,
Alev Dogan
e-mail:alevd@sirius.gazi.edu.tr
                                    


From owner-software@net.bio.net Mon Jul 05 16:57:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!news.indiana.edu!not-for-mail
From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: Re: Compiling treetool for Linux - any success?
Date: 5 Jul 1999 17:51:09 GMT
Organization: Biology, Indiana University - Bloomington
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You may want to look at Phylodendron (a tool for phylogenetic
tree drawing written in Java). See
http://iubio.bio.indiana.edu/treeapp/  and
http://iubio.bio.indiana.edu/soft/molbio/java/apps/trees/

- Don

--
-- d.gilbert--bioinformatics--indiana-u--bloomington-in-47405
-- gilbertd@bio.indiana.edu

From owner-software@net.bio.net Tue Jul 06 03:10:00 1999
Path: biosci!agate!newsfeed.berkeley.edu!nntp.flash.net!news.flash.net!not-for-mail
Message-ID: <37818115.DE9AC611@workingobjects.com>
From: Wayne Parrott <wayne@workingobjects.com>
Organization: WorkingObjects.com
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Subject: [ANN]PharmTools for Blast and BlastXML Report Processing Available
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PharmTools SDK Suite(TM) (Version 1.0)

Announcing the free availability of PharmTools SDK Suite(TM) Version 1.0
from WorkingObjects.com. PharmTools SDK is a collection of reusable Java
frameworks and toolkits for use in the development of bioinformatics
applications. This release includes: the Blast Parsing Framework and
BlastXML-SDK. The Blast Parsing Framework is a set of design patterns
and Java classes for processing native (i.e., local) and NCBI website
generated Blast reports. BlastXML-SDK extends the Blast Parsing
Framework functionality to support the creation and processing of
BlastXML documents. This release includes documentation, a license that
allows it to be freely employed within other products, source code, and
examples.

The PharmTools SDK Suite may be downloaded from the WorkingObjects.com
website at http://www.workingobjects.com.

Wayne Parrott
WorkingObjects.com

From owner-software@net.bio.net Tue Jul 06 05:30:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!easynet-fr!ciril.fr!news.u-strasbg.fr!not-for-mail
From: Julie THOMPSON <julie@titus.u-strasbg.fr>
Newsgroups: bionet.software
Subject: Clustal W, Clustal X version 1.8
Date: Tue, 06 Jul 1999 08:26:32 +0200
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                  Clustal W, Clustal X (Version 1.8) Release


Announcing a release of upgrades to the freely available Clustal W and X

multiple sequence alignment programs. Clustal X provides a windows
interface
(using the NCBI Vibrant toolkit) to Clustal W.

With this release, Clustal X is at last no longer beta test and we can
bring
the version numbers of Clustal X into line with Clustal W. Note the
version 1.8
programs share the same algorithms and parameterisation and produce
exactly the
same alignments.

The main changes to Clustal W are reparameterisation of the alignment
algorithm
and a number of bug fixes (listed in the README). The Gonnet PAM series
is now
the default protein matrix series and gap extension penalty has been
increased.

Clustal X has in addition received a lot of work to the windows
interface.
Users should note that screen refresh is quite slow on all compilations
of
Clustal X. In addition the Mac and PC platforms suffer from a double
refresh
during window resizing. These limitations, though annoying, do not
seriously
affect the utility of the program.

Clustal W and versions of Clustal X for PowerMac, PC (32 bit), and UNIX
(Linux, Alpha, SGI, Sun) can be downloaded from several websites
including:

       IGBMC      ftp://ftp-igbmc.u-strasbg.fr/pub/
        EBI        ftp://ftp.ebi.ac.uk/pub/software/
                   and all sites with mirrors to the EBI

Problems with the 1.8 release may be reported to any of the authors,
including:

Julie Thompson      (julie@igbmc.u-strasbg.fr)
Toby Gibson         (Toby.Gibson@EMBL-Heidelberg.de)
Des Higgins         (des@chah.ucc.ie)
Francois Jeanmougin (pingouin@igbmc.u-strasbg.fr) especially for
LINUX...


******************************************************************************

                  POLICY ON COMMERCIAL DISTRIBUTION OF CLUSTAL W/X

Clustal W/X is freely available to the user community. However, Clustal
W/X
is increasingly being distributed as part of commercial sequence
analysis
packages. To help us safeguard future maintenance and development,
commercial
distributors of Clustal W/X must take out a NON-EXCLUSIVE LICENCE.
Anyone
wishing to commercially distribute version 1.8 of Clustal W/X should
contact the
authors unless they have previously taken out a licence.

******************************************************************************




From owner-software@net.bio.net Tue Jul 06 05:30:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!easynet-fr!ciril.fr!news.u-strasbg.fr!not-for-mail
From: Julie THOMPSON <julie@titus.u-strasbg.fr>
Newsgroups: bionet.software
Subject: Re: Compiling treetool for Linux - any success?
Date: Tue, 06 Jul 1999 08:24:47 +0200
Organization: IGBMC
Lines: 13
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Henrik Seidel wrote:

> Did anybody succeed in compiling treetool on a Linux machine? Or does
> anybody know a Unix or Java tool comparable to Win*s TreeView?
>
> Thanks for any help.
>                                 --- Henrik Seidel

Have you tried NJPLOT from Manolo Guoy (mgouy@biomserv.univ-lyon1.fr).
A linux executable is available.

Julie Thompson


From owner-software@net.bio.net Tue Jul 06 11:22:00 1999
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From owner-software@net.bio.net Tue Jul 06 12:29:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!news.cs.utwente.nl!newsfeed.eris.dera.gov.uk!ftel.ftel.co.uk!warwick!not-for-mail
From: David Jones <jones@globin.bio.warwick.ac.uk>
Newsgroups: bionet.software,sci.bio.misc,sci.chem
Subject: UK PhD Studentship in Bioinformatics
Date: 6 Jul 1999 13:19:00 GMT
Organization: University of Warwick
Lines: 36
Message-ID: <7lsvo4$hhl$1@holly.csv.warwick.ac.uk>
NNTP-Posting-Host: myosin.warwick.ac.uk
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User-Agent: tin/pre-1.4-980618 (UNIX) (Linux/2.2.10 (i686))


UK Bioinformatics PhD for Autumn 1999
=====================================

NOTE: CLOSING DATE IS JULY 23RD 1999


A PhD Studentship is still available in the general area of bioinformatics,
working the laboratory of Dr David Jones. Particular areas of interest
are protein structure prediction, protein fold recognition (threading),
and sequence analysis of genomic sequences (in particular transmembrane
protein sequences.)

The available Studentship is MRC funded and so attracts a significantly
higher stipend than most Studentships (7,000-10,000 pounds / year).

Ideal candidates should have a knowledge of biology and good computational
or mathematical skills. Physics or computer science graduates wishing
to apply their skills to biological problems would also be suitable.

Details of the research interests in the laboratory can be read from the
following WWW page:

http://globin.bio.warwick.ac.uk

Enquiries about these Studentships should be addressed directly to Dr Jones
at the address shown below.

Note that normal eligibility requirements for MRC studentships
apply, so foreign nationals are not eligible, and candidates would
need a 1st or Upper Second class degree (or equivalent).

>---------------------------------------------------------------------------<
Address: Dept. of Biological       |   Email: jones@globin.bio.warwick.ac.uk
Sciences, University of Warwick,   |     Tel: +44 1203 523729
Coventry CV4 7AL, U.K.             |     Fax: +44 1203 523701

From owner-software@net.bio.net Tue Jul 06 15:18:00 1999
Path: biosci!newshost.lanl.gov!not-for-mail
From: Carla Kuiken <kuiken@lanl.gov>
Newsgroups: bionet.software,bionet.jobs
Subject: Job opening at HIV Database in Los Alamos
Date: Tue, 06 Jul 1999 10:12:37 -0600
Organization: Los Alamos National Laboratory
Lines: 32
Message-ID: <37822AF5.3683@lanl.gov>
NNTP-Posting-Host: intron.lanl.gov
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We have a job opening for a Graduate Research Assistant with a
background in biology or immunology. The job entails assisting the staff
and postdocs doing sequence analyses using existing and new methods,
helping maintain and expand the website, literature searches, annotating
the sequence database, and assisting in the production of the two yearly
Compendia (HIV Sequences and Immunology). Depending on the skills of the
GRA, scripting and programming (Perl, C/C++, javascript) can become part
of the tasks as well. There are some possibilities for computer training
on the job.

We are looking for someone with a background in biology or immunology
who is able to work independently on challenging data analysis as well
as data annotation and routine sequence alignments. A background in
sequence analysis or genetics is helpful, but not required. Some
computer experience is necessary, preferably on a UNIX platform.
Programming skills would be an asset.   

The HIV Database and Analysis Group has ongoing collaborations with
major HIV research groups worldwide. There is a lot of room to expand
new ideas and initiatives and to develop new skills. The salary is
excellent, and the living environment is one of the best in the country.
The GRA program is designed for people who have a bachelors degree or a
masters degree, and want ultimately to go on with further graduate
studies. GRAs are hired for a period of one year, after which they have
to enroll into a graduate program in order to be allowed to continue
working as a GRA. The nearby University of New Mexico offers a fairly
large selection of graduate programs.   

For more information or to apply, please send an email to Carla Kuiken
(kuiken@lanl.gov).

http://hiv-web.lanl.gov

From owner-software@net.bio.net Tue Jul 06 18:16:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!uchinews2!newsswitch.lcs.mit.edu!newsfeed.enteract.com!news.maxwell.syr.edu!newsfeed.nacamar.de!fu-berlin.de!news.icm.edu.pl!not-for-mail
From: Piotr Kozbial <piotrk@ibb.waw.pl>
Newsgroups: bionet.software
Subject: Database integration with sequence analysis software - how?
Date: Tue, 06 Jul 1999 21:14:00 +0200
Organization: http://news.icm.edu.pl/
Lines: 31
Message-ID: <37825578.A352B0CC@ibb.waw.pl>
Reply-To: piotrk@ibb.waw.pl
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I am interested in testing several ideas about organization of genomic
information. 

Could you please send me references about:

1. Sequences management in relational databases.
Databases, I know, store data in tables and rows, but sequences seems to
be stored in flat files (i.e. in FASTA format). Is it good idea to chop
the sequences and transfer them into relational database? Some kinds of
sequences are well suited for storage in relational database (i.e.
protein and cDNA sequences), but genomic sequences are not. Is it good
idea to cut genomic sequences into fragments containing  ORFs with
theirs upstream and downstream sequence, and with some positioning
information (i.e.. IDs of upstream and downstream ORFs). With each ORF
in the database it is possible to store additional information (computed
or taken from known literature) like: 
-cDNA sequence, 
-IDs of known aa motives, 
-ID of known conserved structural domains,
-ID of interacting proteins,
-pre computed information about structural, sequence, and functional
homologies (similar to "neighbors" in NCBI databases),
-all other information (especially raw experimental data),

2. There are lots of tools for sequence analysis written in perl, c,
c++, etc.
How the interface between the database and the tools should be designed?
Are there any examples?

TIA
Piotr

From owner-software@net.bio.net Wed Jul 07 00:42:00 1999
Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!209.50.235.254!europa.netcrusader.net!204.127.161.3!wn3feed!worldnet.att.net!wnmaster2!not-for-mail
From: "Ron Robinson II" <crobinsonii@worldnet.att.net>
Newsgroups: bionet.software
Subject: Help! looking for software
Date: Tue, 6 Jul 1999 06:39:18 -0700
Organization: AT&T WorldNet Services
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I am looking for (and don't laugh) a copy of DOS 3.0 Plus ?
if anyone could help, possibly e-mail me a copy, it would be appreciated. A
freind still uses it and lost some files.
Thanks....



From owner-software@net.bio.net Wed Jul 07 06:52:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!tank.news.pipex.net!pipex!server1.netnews.ja.net!pegasus.csx.cam.ac.uk!hgmp.mrc.ac.uk!biosci
From: ajenkins@nibsc.ac.uk (Adrian Jenkins)
Newsgroups: bionet.software
Subject: Re: ACCESS NEEDED!!!
Date: 7 Jul 1999 08:45:45 +0100
Organization: NIBSC
Lines: 52
Message-ID: <3783058F.6298DD29@nibsc.ac.uk>
References: <37823C40.5E5D12F@email.com>
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X-To: "Sten A. Hankewitz" <stenah@email.com>
X-CC: bio-software@hgmp.mrc.ac.uk


Hi there to you.

I have recently bought a lap top together with my girlfriend

We too would like to have access, Word, Excel etc.

The only source of the software is the local Microsoft dealer.

So, please take your credit card and purchase it.



"Sten A. Hankewitz" wrote:
> 
> Hi!
> 
> I desperately need Microsoft Access 97 or 95 or actually whatever. Can
> someone PLEASE tell me the URL I can find it in or maybe some good
> person will send it to me by mail.
> 
> I really need it!!!
> 
> Thank you!
> 
> Sten
> stenah@email.com

-- 


Enjoy....

Adrian

%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

        NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL

        Adrian Jenkins          Molecular Virology Group
				Division of Retrovirology               
                                e-mail     ajenkins@nibsc.ac.uk         
                                http://www.nibsc.ac.uk/      
          
	"No plan survives contact with the enemy"  von Moltke

	"To Errr  is human, but when the eraser wears out
	ahead of the pencil; you're overdoing it."
							  Anon

%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
---

From owner-software@net.bio.net Wed Jul 07 07:25:00 1999
Path: biosci!newshost.lanl.gov!logbridge.uoregon.edu!dispose.news.demon.net!demon!ayres.ftech.net!news.ftech.net!bignews.mediaways.net!f.de.uu.net!do.de.uu.net!uunet!ams.uu.net!iafrica.com!news.adamastor.ac.za!not-for-mail
From: Gian van der Spuy <gvds@gerga.sun.ac.za>
Newsgroups: bionet.software
Subject: How to run xview
Date: Wed, 07 Jul 1999 10:19:03 +0200
Organization: Adamastor
Message-ID: <37830D77.323B1FD@gerga.sun.ac.za>
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<!doctype html public "-//w3c//dtd html 4.0 transitional//en">
<html>
Based on advice from this group I have downloaded and compiled namot. I
have also installed the xview libraries and binaries. I am quite new to
Linux so pardon me if this is a silly question, but how do I now run xview
and get namot running in it.
<p>--
<br>Gian van der Spuy
<br>Molecular and Cellular Biology
<br>University of Stellenbosch
<br>South Africa
<br>&nbsp;</html>


From owner-software@net.bio.net Wed Jul 07 18:33:00 1999
Path: biosci!COMPUTER.ORG!fvega
From: fvega@COMPUTER.ORG ("Francisco M. De La Vega")
Newsgroups: bionet.software
Subject: DEADLINE SOON: SNP Data analysis & Mgmnt @ PSB'2000
Date: 7 Jul 1999 12:33:10 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 127
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <3783A867.87B94553@computer.org>
NNTP-Posting-Host: net.bio.net

Dear Colleague,

Please note that the deadline for paper submissions to the "Analysis,
Management and Application of SNP Data" is due on July 12, 1999.
Additional information is attached.

I encourage you to submitt a contribution on that date; however let me
know if you are interested in submitting, but have difficulty meeting
this deadline.

Sincerely,

Francisco M. De La Vega
PE Biosystems

==================================================
Human Genome Variation: Analysis, Management and Application
of SNP Data

A session of the Pacific Symposium on Biocomputing 2000,
Honolulu, Hawaii, January 5-9, 2000


Recently there has been considerable interest in using
single nucleotide polymorphisms (SNP) for the understanding
of complex diseases and for pharamacogenetics. The human
genetics community, both private and academic, is engaged in
large scale SNP discovery efforts and assay development.
With the imminent development of high throughput
methodologies for automating the SNP discovery and screening
process, it is likely that many if not all of the common
polymorphisms will be identified and characterized in the
next several years.

As is often the case, data production may outpace current
data management and analysis capabilities. New, specialized
SNP databases are being designed and implemented to capture
the impending flood of polymorphism data. Comprehensiveness
of the captured data and the exploration of its intellectual
content is essential. Computational methods and tools to
handle and analyze polymorphism data flow will certainly
play an important role in this challenge.

Call for Participation

The PSB 2000 session "Human Genome Variation: Analysis,
Management and Application of SNP Data" aims to provide a
timely forum in this area, bringing together computer
scientists, bioinformatics specialists and biologists, from
academia and industry, to address the forthcoming problems
in the utilization of SNP information.

We encourage academic, industrial and government scientists
to submit manuscripts. In addition to a session for oral
presentation of novel peer-reviewed contributions, there
will be a panel discussion devised to foster exchange
between industry and academic scientists. Participants are
invited to discuss their issues with other peers in this
panel session. Posters and computer demonstrations are also
requested to complement the session.

Topics

The contributions should pose and discuss a specific problem
that the biocomputing community will need to address,
describe models, or propose specific solutions to a problem.
Sequence polymorphisms will be the common theme, but the
computational or theoretical contributions can span areas
ranging from population genetics and evolution to data
visualization and management.

Among the anticipated topics are:

Automation of large scale SNP genotyping.
Data management and integration for SNP genotyping systems.
Evolutionary aspects of genome variability and SNP analysis.
Ontologies for human genome variation.
SNP database mining and knowledge discovery.
Statistical methods for SNP analysis.
Tools for high throughput SNP discovery and screening.
Visualization and analysis of SNP data.

Submissions

PSB will publish accepted full papers in an archival
proceedings indexed in MEDLINE. All contributed papers will
be rigorously peer-reviewed by at least three referees. A
limited number of papers will be selected for a 30-minute
oral presentation to the full assembled conference. Accepted
poster abstracts will be distributed at the conference
separately from the archival Proceedings. Please prepare
your submission according to the instructions found at the
Web page:
http://www.cgl.ucsf.edu/psb/cfp-snp.html

Dates & Deadlines

Paper submissions due: July 12, 1999
Notification of paper acceptance: August 27, 1999
Camera ready of accepted papers due: September 24, 1999
Abstract deadline: October 1, 1999
Meeting: January 5-9, 2000

Conference Information

The Pacific Symposium on Biocomputing (PSB 2000) is an
international, multidisciplinary conference for the
presentation and discussion of current research in the
theory and application of computational methods in problems
of biological significance. PSB 2000 will be held January 5-
9, 2000, in Honolulu, Hawaii at the Sheraton Waikiki. For
more information see the official PSB 2000 Web page at :
http://www.cgl.ucsf.edu/psb/

Session Chairs

Francisco M. De La Vega, Synthesis and Arrays R&D,
PE Biosystems, Foster City, CA, USA.
E-mail: DelaveFM@pebio.com

Martin Kreitman, Department of Ecology and Evolution,
University of Chicago, Chicago, IL, USA.
E-mail: mkre@midway.uchicago.edu





From owner-software@net.bio.net Wed Jul 07 20:11:00 1999
Path: biosci!daresbury!uninett.no!Norway.EU.net!uio.no!news.netg.se!news-peer-europe.sprintlink.net!news.sprintlink.net!howland.erols.net!nntp.abs.net!newshub2.home.com!news.home.com!news2.rdc1.on.home.com.POSTED!not-for-mail
From: "StannyP" <StanP9@home.com>
Newsgroups: alt.comp.software.financial.peachtree,alt.fan.dean-stark.software.tester,alt.geo-software,alt.med.software,alt.video.dvd.software,bionet.software,bionet.software.acedb,bionet.software.gcg
Subject: Top Quality Software Testing Services by Software Testing Lab Inc. for FREE!!!
Lines: 42
Organization: TranceSundayProject
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Xref: biosci bionet.software:23792 bionet.software.acedb:2454 bionet.software.gcg:3615

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From owner-software@net.bio.net Thu Jul 08 00:24:00 1999
Path: biosci!sanger.ac.uk!solovyev
From: solovyev@sanger.ac.uk ("Victor Solovyev")
Newsgroups: bionet.software
Subject: Genes_in_Pictures (Human/Drosophila)
Date: 7 Jul 1999 18:24:28 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 104
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9907080218.ZM28768@octane>
NNTP-Posting-Host: net.bio.net

==============================================================
        Genes_in_Pictures (Human/Drosophila)
==============================================================
Part of Infogen database - Known genes of Human and Drosophila
and Visualization of their functional signals is available at

             http://genomic.sanger.ac.uk/

 These Infogene files and Java Viewer of Gene structures is design by
           Igor Seledtsov and Victor Solovyev for

Infogen is designed as a resource of information about genes
  and their components

Java Viewer will be used for

a) Visually inspection of gene structure in Infogene entries
   of known or predicted genes

b) In interactive Gene prediction in annotation genomic sequences
   from genome sequencing Projects


 HOW TO WORK WITH Genes_in_Pictures: see Help menu in Java Viewer: About
		  Infogene format see Help menu in Java Viewer: Infogen
		  Clicking by mouse you	can see Infogen gene description
                                                       (see Help: About)
  General Picture of GENBANK/INFOGENE content:

   HUMAN GENES IN GENBANK/INFOGENE:

CDS total                      34448
Partial  CDS                   20585
RNA CDS Total                  24306
Partial RNA CDS                13329
DNA CDS Total                  10142
Partial DNA CDS                7256
Exons Total                    36674
Partial Exons                  10985
Exons Total                    36674
Genes Total                    10142
Partial Genes                  8226
Acceptor Site Total                26507
Acceptor Site standart             25902 ( 97.72%)
Acceptor Site putative             3024
Acceptor Site putative standart    2949  ( 97.52%)
Acceptor Site nonputative          23483
Acceptor Site nonputative standart 22953 ( 97.74%)
Donor Site Total                22341
Donor Site standart             21916 ( 98.10%)
Donor Site putative             2662
Donor Site putative standart    2596  ( 97.52%)
Donor Site nonputative          19679
Donor Site nonputative standart 19320 ( 98.18%)
Start codons                    13854
Standart Start codons           13694 ( 98.85%)
Stop codons                     13810
Standart Stop codons            13810 (100.00%)
CAAT-boxes      /Total/Putative/Experimental        405    51     2
TATA-boxes      /Total/Putative/Experimental        802   119    14
TSP (Cap sites) /Total/Putative/Experimental       2554   128   118
PolyA signals   /Total/Putative/Experimental       3548   444    85
PolyA sites     /Total/Putative/Experimental       2066    77    81

   DROSOPHILA MELANOGASTER GENES IN GENBANK/INFOGENE:

CDS total                      3521
Partial  CDS                   1025
RNA CDS Total                  1865
Partial RNA CDS                316
DNA CDS Total                  1656
Partial DNA CDS                709
Exons Total                    4648
Partial Exons                  1840
Exons Total                    4648
Genes Total                    1656
Partial Genes                  753
Acceptor Site Total                3043
Acceptor Site standart             2870 ( 94.31%)
Acceptor Site putative             135
Acceptor Site putative standart    133  ( 98.52%)
Acceptor Site nonputative          2908
Acceptor Site nonputative standart 2737 ( 94.12%)
Donor Site Total                2014
Donor Site standart             1873 ( 93.00%)
Donor Site putative             70
Donor Site putative standart    69   ( 98.57%)
Donor Site nonputative          1944
Donor Site nonputative standart 1804 ( 92.80%)
Start codons                    2496
Standart Start codons           2475 ( 99.16%)
Stop codons                     2476
Standart Stop codons            2476 (100.00)
CAAT-boxes      /Total/Putative/Experimental         39     4     0
TATA-boxes      /Total/Putative/Experimental        217    24     3
TSP (Cap sites) /Total/Putative/Experimental        539    10    35
PolyA signals   /Total/Putative/Experimental        773   104    20
PolyA sites     /Total/Putative/Experimental        420     7    19

-- 
Victor Solovyev
The Sanger Centre, Hinxton, Cambridge CB10 1SA, UK
Email: solovyev@sanger.ac.uk  http://genomic.sanger.ac.uk
Phone: 44-1223-494799  FAX:   44-1223-494919

From owner-software@net.bio.net Thu Jul 08 15:46:00 1999
Path: biosci!newshost.lanl.gov!logbridge.uoregon.edu!dispose.news.demon.net!demon!colt.net!baron.netcom.net.uk!netcom.net.uk!server3.netnews.ja.net!news.ox.ac.uk!not-for-mail
From: James Cuff <james@ebi.ac.uk>
Newsgroups: bionet.software
Subject: [ANNOUNCE] Secondary structure prediction mail list
Date: Thu, 08 Jul 1999 17:40:15 +0100
Organization: European Bioinformatics Institute
Message-ID: <3784D46F.167E@ebi.ac.uk>
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Dear colleagues,

We are happy to announce a combined Jpred and secondary structure
prediction discussion mailing list. 

It is planned that the list will act as forum for discussion of protein
secondary structure prediction methods and sequence/structure analysis
techniques.

The mailing list will also be used to keep subscribers up to date with
improvements to the Jpred secondary structure prediction WWW server. 
Announcements of new prediction methods and relevant papers on
prediction are also very much welcomed. 

The jpredusers mailing list can be accessed by sending an e-mail to
majordomo@ebi.ac.uk, with the body message containing the words: 

subscribe jpredusers

More information can be found at: 

http://barton.ebi.ac.uk/

Best regards,

James.

p.s. Sorry if this message has popped out twice - we have been 
having problems with our newsfeed at the HGMP
 
-----------------------------------------------------------------
        James Cuff          |  European Bioinformatics Institute
  +44 (0) 1223 49 4607      |     Wellcome Trust Genome Campus
      james@ebi.ac.uk       |   Hinxton, Cambridge. CB10 1SD, UK
-----------------------------------------------------------------

From owner-software@net.bio.net Thu Jul 08 18:15:00 1999
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From: Jackie Spector <jspector@netgenics.com>
Newsgroups: bionet.software
Subject: Bio-Ontologies '99
Date: Thu, 08 Jul 1999 15:08:15 -0400
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--------------749194EA5D56C4448950C21F
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Dear Bio-Ontologist:

I would like to invite you to the Second Annual Bio-Ontologist Meeting
(Bio-Ontologies 99), on August 5th in Heidelberg, Germany. This is
immediately before ISMB-99  August 6-10 in Heidelberg. Last year's
kick-off meeting was a great success, and was a clear indication of the
general interest and support people had for Ontologies in the life
sciences. The goal of this consortium is the identification and
promotion of a practical set of technologies that will aid in the
knowledge management and exchange of concepts and representations in the
life sciences. This meeting will focus on current issues and activities
that are described in more details below:

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	io-ontology/bio_ontologies-99.html"

<html>



<head>

<title>Bio Ontologies </title>

<meta name="Microsoft Theme" content="none">

</head>



<body>



<h1 align="center"><font face="Book Antiqua">Bio-Ontologies '99</font><font face="Arial"><br>

</font><small><font face="Book Antiqua">Heidelberg, Germany<br>

5 August 1999</font></small></h1>



<p align="center"><img src="WB00668_.gif" width="366" height="31"

alt="WB00668_.gif (22594 bytes)"></p>



<p align="center"><font face="Book Antiqua"><strong>Announcing the Second Annual

Bio-Ontologies Meeting <br>

sponsor by <a href="http://www.NetGenics.com">NetGenics, Inc</a>. and <a

href="http://www.sb.com">SmithKline Beechman</a></strong></font></p>



<hr>



<p align="left"><font face="Book Antiqua" size="2" color="#804000"><strong>Fellow

Bio-Ontologist:<br>

<br>

I would like to invite you to the Second Annual Bio-Ontologist Meeting (Bio-Ontologies

99), on August 5th in Heidelberg, Germany. This is immediately before ISMB-99&nbsp; August

6-10 in Heidelberg. Last year's kick-off meeting was a great success, and was a clear

indication of the general interest and support people had for Ontologies in the life

sciences. The goal of this consortium is the identification and promotion of a practical

set of technologies that will aid in the knowledge management and exchange of concepts and

representations in the life sciences. This meeting will focus on current issues and

activities that are described in more details below:</strong></font></p>

<div align="left">



<table border="1" width="130" bordercolor="#804000" align="left" cellspacing="3"

bgcolor="#B95C00">

  <tr>

    <td width="126"><p align="center"><font face="Book Antiqua" color="#000000"><em><strong><small>Purpose

    and Scope</small></strong></em></font></td>

  </tr>

</table>

</div>



<p>&nbsp;</p>

<font color="#000000" face="Arial" size="2">



<p></font><font face="Book Antiqua" color="#000000" size="2">Many in the group have been

active since our last meeting and an agenda is being planned that will include the work

currently being done in the following areas:</font> 



<ul>

  <li><font face="Book Antiqua" color="#000000" size="2">Results from analyses and experiments

    on how to effectively exchange Ontologies, including a recommendation for a Common

    Ontologies Exchange Language</font></li>

  <li><font face="Book Antiqua" color="#000000" size="2">Presentation of ontologies produced

    by members from various genomics efforts (e.g. Flybase, Saccharomyces GD, Mouse GB, ACeDB,

    Arabidopsis DB</font></li>

  <li><font face="Book Antiqua" color="#000000" size="2">Specific uses of ontologies in

    research and drug discovery with special focus on Pre-Competitive Ontologies for the

    industry</font></li>

</ul>

<font color="#000000" face="Arial" size="2">



<p align="left"></font><font face="Book Antiqua" color="#000000" size="2">We would like to

invite others to present their work and views on both uses and&nbsp; modeling of

biological ontologies</font><font face="Book Antiqua"><font color="#000000" size="2">. </font><strong><font

color="#000000"><small>Please submit abstracts for short talks or posters by July 1, 1999,

to</small></font><font size="2"> </font></font><font face="Book Antiqua" size="2"><a

href="mailto:ENeumann@NetGenics.com">Eric Neumann, PhD.</a></font><font

face="Book Antiqua"> </strong><small>of NetGenics, Inc</small><strong> or <small><a

href="mailto:Robin_A_McEntire@sbphrd.com">Robin A. McEntire</a></small> </strong><font

color="#000000"><small>of SmithKline Beechman.</small><br>

</font><br>

<small><strong>Some intended results of the meeting are</strong>:</small></font></p>



<ul>

  <li><font face="Book Antiqua" color="#000000" size="2">Action items to focus on what

    ontological and knowledge-management tools are available</font></li>

  <li><font face="Book Antiqua" color="#000000" size="2">Work group addressing development of

    ontologies in particular areas of the Life Sciences, e.g. molecular biology, genetics,

    metabolic and signaling pathways, etc.</font></li>

  <li><font face="Book Antiqua" color="#000000" size="2">Further support from other

    bio-research groups, as well as backing from industry</font></li>

  <li><font face="Book Antiqua" color="#000000" size="2">Dissemination of information and

    results produced by this consortium</font></li>

</ul>

<div align="left">



<table border="1" width="130" bordercolor="#804000" align="left" cellspacing="3"

bgcolor="#B95C00">

  <tr>

    <td width="126"><p align="center"><font face="Book Antiqua" color="#000000"><em><strong><small>Facilities</small></strong></em></font></td>

  </tr>

</table>

</div>



<p><br>

<br>

<font face="Book Antiqua" size="2">The workshop will be held at the <a

href="http://www.marriotthotels.com/hdbmc"><strong>Marriott in Heidelberg</strong></a>

which is one of the participating ISMB hotels and facilities. <font color="#000000">Attendees

are expected to make their own arrangements for travel and accommodation (we assume most

will simply extend their bookings for ISMB). For more info on hotels with special ISMB

conference rates, see</font></font><font color="#0000FF" face="Book Antiqua" size="2"> <strong><a

href="http://ismb99.gmd.de/hotel.html" target="_blank">http://ismb99.gmd.de/hotel.html</a></strong>.</font></p>

<div align="left">



<table border="1" width="130" bordercolor="#804000" align="left" cellspacing="3"

bgcolor="#B95C00">

  <tr>

    <td width="126"><p align="center"><font face="Book Antiqua" color="#000000"><em><strong><small>Registration

    &amp; Fees</small></strong></em></font></td>

  </tr>

</table>

</div>



<p><font color="#000000" face="Arial" size="2"><br>

<br>

</font><font color="#000000" size="2" face="Book Antiqua">We have elected to charge a

small fee to cover the incidental costs of organizing the workshop.&nbsp; Registration

fees will be $30 for students/postdocs, $45 for other academics and $60 for industry or

commercial attendees. Registration includes coffee, tea, lunch and all workshop materials.

<strong>Deadline for advanced registration is July 15</strong>.</font></p>



<p align="center"><font color="#000000" size="2" face="Book Antiqua">&nbsp; All fees

should be made payable in US dollars to NetGenics Bio-Ontolgies '99 and mailed to:<br>

<strong>NetGenics, Inc. <br>

1717 East Ninth Street<br>

Suite 1600<br>

Cleveland, OH 44114<br>

Attn: Bio-Ontologies '99</strong></font></p>



<blockquote>

  <div align="center"><center><table border="1" width="45%" cellpadding="0">

    <tr>

      <td width="100%" colspan="2" align="center" bgcolor="#B95C00"><font color="#000000"

      size="2" face="Book Antiqua"><strong>Important Dates to Remember</strong></font></td>

    </tr>

    <tr>

      <td width="72%" align="left"><font color="#000000" size="2" face="Book Antiqua">Registration

      begins:&nbsp; </font></td>

      <td width="28%" align="left"><font color="#000000" size="2" face="Book Antiqua">May 1,

      1999</font></td>

    </tr>

    <tr>

      <td width="72%" align="left"><font color="#000000" size="2" face="Book Antiqua">Abstract

      submissions due:</font></td>

      <td width="28%" align="left"><font color="#000000" size="2" face="Book Antiqua">July 1,

      1999</font></td>

    </tr>

    <tr>

      <td width="72%" align="left"><font color="#000000" size="2" face="Book Antiqua">Bio-Ontologies

      final schedule:</font></td>

      <td width="28%" align="left"><font color="#000000" size="2" face="Book Antiqua">July 1,

      1999</font></td>

    </tr>

    <tr>

      <td width="72%" align="left"><font color="#000000" size="2" face="Book Antiqua">Registration

      and payment due:</font></td>

      <td width="28%" align="left"><font color="#000000" size="2" face="Book Antiqua">July 15,

      1999</font></td>

    </tr>

    <tr>

      <td width="100%" align="left" colspan="2" bgcolor="#B04B09">&nbsp;</td>

    </tr>

  </table>

  </center></div>

</blockquote>



<p align="center"><font face="Book Antiqua" size="3" color="#0000FF"><a target="_parent"

href="BioOntologies_Register_form.html"><strong>Go to Registration Form</strong></a><br><a href="index.html">Home</a></font></p>



<hr>



<p>&nbsp;</p>



<p>&nbsp;</p>

</body>

</html>


--------------749194EA5D56C4448950C21F--


From owner-software@net.bio.net Sat Jul 10 14:29:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!remarQ73!supernews.com!remarQ.com!news.usenetserver.com!uunet!ffx.uu.net!newsfeed.attap.net!infeed.jaring.my!not-for-mail
From: "Khoo" <khoopj@pc.jaring.my>
Newsgroups: bionet.software
Subject: Can anyone help me with this problem in Microsoft Access97
Date: Sat, 10 Jul 1999 23:28:37 +0800
Organization: Unconfigured
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I am Khoo from Malaysia. I am building a database for my school to record
all the students names, address, and etc...
        Now I want to build a search engine for it to let user search for
first names or the first alphabates of the name....
        Please help me


Sincerely
Khoo



From owner-software@net.bio.net Sun Jul 11 00:16:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!arclight.uoregon.edu!hammer.uoregon.edu!newsfeed.direct.ca!tank.news.pipex.net!pipex!uunet!ams.uu.net!ffx.uu.net!in5.uu.net!PM01NEWS!not-for-mail
Message-ID: <3787EF0C.B985F1FE@mciworld.com>
From: "Jeremy.Parsons" <jeremy.parsons@mciworld.com>
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Subject: Re: Seeking: SCF-file (sequencing data) viewer for Mac!
References: <3777B048.A2EA0A67@uni-tuebingen.de>
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You might want to try  a Java trace viewer: have a look around
http://www.ebi.ac.uk/~jparsons

jeremy

Eric Beitz wrote:

> Hi all,
>
> is there a freeware viewing software for so-called SCF-files for the
> Macintosh? These files are produced by our LiCor sequencer (OS2) and contain
> the graphical display of the sequencing raw data. I want to analyse the data
> on my PowerBook which is much more convenient for me.
>
> Any sugestions welcome!
>
> Thanks,
> Eric


From owner-software@net.bio.net Sun Jul 11 00:22:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!uchinews2!yellow.newsread.com!netaxs.com!newsread.com!newspeer1.nac.net!news.new-york.net!uunet!ffx.uu.net!in5.uu.net!PM01NEWS!not-for-mail
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From: "Jeremy.Parsons" <jeremy.parsons@mciworld.com>
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Newsgroups: bionet.software
Subject: Re: ABI electrophoretograms on PC=>what about assembly programs?
References: <3771B469.2B3A1680@flinders.edu.au> <3778b1c8.18163102@news.iastate.edu>
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You can view using a Java trace viewer: http://www.ebi.ac.uk/~jparsons
but if you just use files on a PC. and want editing, you would be better off with the
Staden group's Trev http://www.mrc-lmb.cam.ac.uk/pubseq/index.html
If you want an assembler, you could try Staden's Gap4, phrap/consed, Cap3 etc

Jeremy

Chris Kafer wrote:

> What we really need is an assembly program for PCs, like
> Autoassembler, that will take the electropherogram files.  Anyone know
> of freeware/shareware or websites that will do this?  I've found one
> that will take fasta formats but what a pain to have to take 40 or
> more text sequences and reformat them.
>
> On 23 Jun 1999 21:35:28 -0700, Lee.Smith@FLINDERS.EDU.AU (Lee Smith)
> wrote:
>
> >Hi
> >This may well be covered in a FAQ, but then I can't find that either!
> >Does anyone have any suggestions for software to allow editing/viewing
> >of
> >the electrophoretograms produced by an ABI sequencer on a PC?
> >Obviously shareware/freeware prefered!
> >
> >Lee Smith
> >Flinders University
> >SA 5042
> >Australia
> >
> >Lee.Smith@flinders.edu.au
> >


From owner-software@net.bio.net Mon Jul 12 13:07:00 1999
Path: biosci!newshost.lanl.gov!logbridge.uoregon.edu!infeed.is.co.za!feeder.is.co.za!hermes.is.co.za!not-for-mail
From: "winhide" <winhide@sanbi.ac.za>
Newsgroups: bionet.software
Subject: SANBI executables
Date: Mon, 12 Jul 1999 15:56:15 +0200
Organization: An Internet Solution Customer
Lines: 78
Message-ID: <7mcs82$qn3$1@hermes.is.co.za>
References: <37830D77.323B1FD@gerga.sun.ac.za>
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This is a multi-part message in MIME format.

------=_NextPart_000_0088_01BECC7F.126B7E20
Content-Type: text/plain;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable

SA Specific:

We are supporting Linux executables, the first, are those that are =
already supported at Pasteur Institute. Please feel free to subscribe to =
the SA bioinformatics news group at: fourie@sanbi.ac.za )if you are in =
SA)

Win
    Gian van der Spuy wrote in message =
<37830D77.323B1FD@gerga.sun.ac.za>...
    Based on advice from this group I have downloaded and compiled =
namot. I have also installed the xview libraries and binaries. I am =
quite new to Linux so pardon me if this is a silly question, but how do =
I now run xview and get namot running in it.=20
    --=20
    Gian van der Spuy=20
    Molecular and Cellular Biology=20
    University of Stellenbosch=20
    South Africa=20
     =20


------=_NextPart_000_0088_01BECC7F.126B7E20
Content-Type: text/html;
	charset="iso-8859-1"
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<!DOCTYPE HTML PUBLIC "-//W3C//DTD W3 HTML//EN">
<HTML>
<HEAD>

<META content=3Dtext/html;charset=3Diso-8859-1 =
http-equiv=3DContent-Type><!doctype html public "-//w3c//dtd html 4.0 =
transitional//en">
<META content=3D'"MSHTML 4.72.3110.7"' name=3DGENERATOR>
</HEAD>
<BODY bgColor=3D#ffffff>
<DIV><FONT color=3D#000000 face=3DArial size=3D2>SA =
Specific:</FONT></DIV>
<DIV><FONT color=3D#000000 face=3DArial size=3D2></FONT>&nbsp;</DIV>
<DIV><FONT face=3DArial size=3D2>We are supporting Linux executables, =
the first, are=20
those that are already supported at Pasteur Institute. Please feel free =
to=20
subscribe to the SA bioinformatics news group at: <A=20
href=3D"mailto:fourie@sanbi.ac.za">fourie@sanbi.ac.za</A> )if you are in =

SA)</FONT></DIV>
<DIV><FONT face=3DArial size=3D2></FONT>&nbsp;</DIV>
<DIV><FONT face=3DArial size=3D2>Win</FONT></DIV>
<BLOCKQUOTE=20
style=3D"BORDER-LEFT: #000000 solid 2px; MARGIN-LEFT: 5px; PADDING-LEFT: =
5px">
    <DIV>Gian van der Spuy<GVDS@GERGA.SUN.AC.ZA> wrote in message &lt;<A =

    =
href=3D"mailto:37830D77.323B1FD@gerga.sun.ac.za">37830D77.323B1FD@gerga.s=
un.ac.za</A>&gt;...</DIV>Based=20
    on advice from this group I have downloaded and compiled namot. I =
have also=20
    installed the xview libraries and binaries. I am quite new to Linux =
so=20
    pardon me if this is a silly question, but how do I now run xview =
and get=20
    namot running in it.=20
    <P>-- <BR>Gian van der Spuy <BR>Molecular and Cellular Biology=20
    <BR>University of Stellenbosch <BR>South Africa <BR>&nbsp;=20
</P></BLOCKQUOTE></BODY></HTML>

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From owner-software@net.bio.net Mon Jul 12 14:39:00 1999
Path: biosci!sanger.ac.uk!solovyev
From: solovyev@sanger.ac.uk ("Victor Solovyev")
Newsgroups: bionet.software
Subject: Plant and Nematode HMM GeneFinders (FGENESH)
Date: 12 Jul 1999 08:39:29 -0700
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     We installed New PLANT AND NEMATODE
specific gene-finding for HMM based program FGENESH
    for multiple gene prediction in  genomic DNA

  (in addition to HUMAN AND DROSOPHILA gene predictors)

It is available at http://genomic.sanger.ac.uk/ of our
Computational Genomic Group WEB server
(http://genomic.sanger.ac.uk/gf/gf.html)


Accuracy of the program is about 90% at the nucleotide level
to predict coding exons (AC = 0.5 (Sn + Sp)).

TO USE  specific version click Plant or Nematode button + fgenesh button


   Past your sequence to the window or load your file with sequence in FASTA
fromat

Example of output of the program:

fgenesh  Mon Jul 12 16:28:07 BST 1999
 FGENESH 1.0 Prediction of potential genes in Plant(Dct) genomic DNA
 Time:   Mon Jul 12 16:28:07 1999
 Seq name: CGG WEB SERVER PAST Sequence
 Length of sequence:  4253  GC content: 37 Zone: 1
 Number of predicted genes 1 in +chain 1 in -chain 0
 Number of predicted exons 3 in +chain 3 in -chain 0
 Positions of predicted genes and exons:
  G Str Feature    Start     End   Score        ORF           Len

  1 +     TSS       15               -3.75
  1 +   1 CDSf    1681 -    1984     42.43    1681 -    1983    303
  1 +   2 CDSi    2162 -    2634     63.01    2164 -    2634    471
  1 +   3 CDSl    2733 -    3584     99.84    2733 -    3584    852
  1 +     PolA    4001               -0.45

Predicted protein(s):
>FGENESH   1   3 exon (s)   1681  -   3584    542 aa, chain +
MAKKGKEVLNALDAAKTQMYHFTAIVIAGMGFFTDAYDLFSISLVTKLLGRIYYHVDSSK
KPGTLPPNVAAAVNGVAFCGTLAGQLFFGWLGDKLGRKKVYGITLMLMVLCSLGSGLSFG
HSANGVMATLCFFRFWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILAGG
IVSLIVSSTFDHAFKAPTYEVDPVGSTVPQADYVWRIVLMFGAIPALLTYYWRMKMPETA
RYTALVARNTKQAASDMSKVLQVDLIAEEEAQSNSNSSNPNFTFGLFTREFARRHGLHLL
GTTTTWFLLDIAYYSSNLFQKDIYTAIGWIPAAETMNAIHEVFTVSKAQTLIALCGTVPG
YWFTVAFIDILGRFFIQLMGFIFMTIFMFALAIPYDHWRHRENRIGFLIMYSLTMFFANF
GPNATTFVVPAEIFPARLRSTCHGISAASGKAGAIVGAFGFLYAAQSSDSEKTDAGYPPG
IGVRNSLLMLACVNFLGIVFTLLVPESKGKSLEEISREDEEQSGGDTVVEMTVANSGRKV
PV




-- 
Victor Solovyev
The Sanger Centre, Hinxton, Cambridge CB10 1SA, UK
Email: solovyev@sanger.ac.uk  http://genomic.sanger.ac.uk
Phone: 44-1223-494799  FAX:   44-1223-494919

From owner-software@net.bio.net Tue Jul 13 14:53:00 1999
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From: Neill White <nwhite@scripps.edu>
Newsgroups: bionet.software
Subject: Biomer : MM/MD on the web
Date: Tue, 13 Jul 1999 15:56:13 +0000
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Dear Colleagues,

This is an announcement of the availability of a new molecular
modeling program - Biomer - that is accessible over the web.
It should be useful as an educational tool as well as a means
to generate structures quickly and easily.  It is written in
Java, and version 1.0a has the following features:

Model Builders for:
    nucleic acids (DNA/RNA)
    polypeptides
    polysaccharides
Interactive molecule editor with fragment libraries
Implementation of the AMBER force field
Geometry Optimization with steepest descent / conjugate gradient
Simulated Annealing with molecular dynamics
Reads / Writes PDB files
Exports jpeg, gif, and ppm images

It is located at http://www.scripps.edu/~nwhite/Biomer/index.html

Regards,
Neill White



From owner-software@net.bio.net Wed Jul 14 16:29:00 1999
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From: Markus Hoenicka <mhoen@farmr1.med.uth.tmc.edu>
Newsgroups: bionet.software
Subject: Q: free restriction analysis software
Date: 14 Jul 1999 12:10:02 +0000
Organization: University of Texas Health Science Center
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I'd like to have a simple tool for restriction analysis, i.e I feed
a sequence file to it and a list of restriction enzymes, and the tool
tells me the number and location of the restriction sites, the length
of the released fragments etc.

It should run on Windows NT, but console applications, incl ANSI C Unix
source code, and perl scripts are actually preferred.

Is anyone aware of such a thing?
TIA
Markus
-- 
Markus Hoenicka
UT Houston Medical School
Dept. of Integrative Biology and Pharmacology
6431 Fannin MSB4.114
Houston, TX 77030
(713) 500-6313, -7476, -7477
(713) 500-7444 (fax)
mhoen@farmr1.med.uth.tmc.edu
http://ourworld.compuserve.com/homepages/hoenicka_markus

From owner-software@net.bio.net Wed Jul 14 16:54:00 1999
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From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software
Subject: Re: Q: free restriction analysis software
Date: 14 Jul 1999 17:48:34 GMT
Organization: Biology, Indiana University - Bloomington
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Sounds like you want Harry Mangalam's nice 'tacg' program.
The below readme may be a bit old, but should get you going.
-- Don

tacg: a program for the restriction enzyme analysis of DNA, V 1.7
      by Harry Mangalam, UC Irvine (mangalam@uci.edu, 714 824 4824)

This file announces the availability and describes the basic functionality
of 'tacg', a command line tool for the restriction enzyme analysis of DNA
for unix-like operating systems.

There is a Web page describing it more fully at:
http://hornet.bio.uci.edu/~hjm/projects/tacg/tacg.main.html

There is also a WWW interface to it so that you can try it out and see if
it's worth downloading:
http://hornet.bio.uci.edu/~hjm/projects/tacg/tacg.form.html

The complete code to implement the Web interface is also available (tho not as
well debugged as the program itself) at:
http://hornet.bio.uci.edu/~hjm/projects/tacg/tacgi

You can always get the latest version in ANSI C source code and several
pre-compiled binaries (unless I move) at:
ftp://mamba.bio.uci.edu/pub/tacg/

--
-- d.gilbert--bioinformatics--indiana-u--bloomington-in-47405
-- gilbertd@bio.indiana.edu

From owner-software@net.bio.net Wed Jul 14 18:05:00 1999
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Subject: CostCrusher LabAudit- Get your costs right to get your decisions right.
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                CostCrusher LabAudit


   Get your costs right to get your decisions right.


What is it?
---------------
CostCrusher LabAudit is a tool to help you and your staff
to make better decisions.

The system models any lab environment so is ideal for
auditing and comparing costs generated by suppliers,
customers, tests and samples performed across workstations
or disciplines.

With CostCrusher you can focus and answer key cost and
performance questions within the lab’s operations and
customer services.

CostCrusher uses the latest Activity Based Costing techniques
to avoid the cost distortion problems inherent in traditional
cost systems (Excel like spreadsheets) that lead to misguided
decisions.


Why CostCrusher?
--------------------------
A modern costing system should:

1)      Uncover & prioritize problems to tackle and solve.
2)      Identify opportunities to exploit.
3)      Influence the behaviour of people.
4)      Stimulate staff to achieve better results - evaluate
        their own performance.

CostCrusher LabAudit introduces a more modern, more relevant
management approach to costs & productivity.


How does it work?
-------------------------
Most cost systems tell one person what was spent from the budget.  
CostCrusher shows each user (in real time):

==> Where, why and how the budget is being spent in their area of
responsibility.

==> Their personal impact on the lab’s cost & productivity.

This helps to make costs transparent and each individual to make 
better decisions in managing their own area.  It encourages a change
in behaviour and raises each person’s productivity leading to (a) an
overall lowering of costs and (b) a feeling of greater responsibility
& motivation.



Profit & Loss - A More Transparent View
--------------------------------------------------------

CostCrusher LabAudit demonstrates a true profit of $ 4.80 where
a profit of $ 11.76 was falsely perceived !


Traditional Costing                 | CostCrusher LabAudit
                                    |
Price or Budget for Sample   35.20  | Price or Budget for Sample       35.20
Direct Material Costs         7.25  | Direct Material Costs             8.50
                                    |                                     
                                    |
Gross Profit                 27.95  | Gross Profit                     26.70
                                    |
                                    |
Less                                | Less
------------------------            | --------------------------
Indirect Material        1.57       | Sample Reception & Handling    2.70
Personnel                6.06       | Consumables Preparation        1.30
Overheads                8.56       | Production                     3.20
                                    | Maintenance & Waste Handling   2.40
                                    | Supplies Management            4.10
                                    | Marketing & Services           2.80
                                    | Customer Administration        5.40
                                    |
                        16.19       |                               21.90
                                    |
Profit (coverage)             11.76 | Profit (coverage)                 4.80
                              ===== |                                  =====
                                    | Less Business Sustaining          2.90
                                    | Costs 
                                    |                                   1.90
                                    |                                  =====

For more information contact:



Michael Piccirillo

TISMO
General Wille-Strasse
Postfach 180
CH-8706 Feldmeilen
Phone: 41-01-923 82 44
Fax:   41-01-923 77 43

Email:   saveit@tismo.com
Website: http://www.costcrusher.com
_______________________________________

Zoe Brooks

QIK Quality Is Key Ltd. 
Phone: (705)866-2074
Toll free Canada & USA:  1-888-222-6252
Fax:   (705)866-2287

Email:    qikinfo@qualityiskey.com
Website:  http://www.qualityiskey.com

From owner-software@net.bio.net Wed Jul 14 18:09:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!cs.utexas.edu!news.uh.edu!news.uth.tmc.edu!not-for-mail
From: Markus Hoenicka <mhoen@farmr1.med.uth.tmc.edu>
Newsgroups: bionet.software
Subject: Re: Q: free restriction analysis software
Date: 14 Jul 1999 14:04:34 +0000
Organization: University of Texas Health Science Center
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I guess that's what I'm looking for!
Thanks
Markus
-- 
Markus Hoenicka
UT Houston Medical School
Dept. of Integrative Biology and Pharmacology
6431 Fannin MSB4.114
Houston, TX 77030
(713) 500-6313, -7476, -7477
(713) 500-7444 (fax)
mhoen@farmr1.med.uth.tmc.edu
http://ourworld.compuserve.com/homepages/hoenicka_markus

From owner-software@net.bio.net Wed Jul 14 19:48:00 1999
Path: biosci!olivet.edu!C-Stanley
From: C-Stanley@olivet.edu (Conrad Stanley)
Newsgroups: bionet.software
Subject: (no subject)
Date: 14 Jul 1999 13:48:49 -0700
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I am researching prairie pollinators and am in desperate need of a
key!!!!!!  Could you assist me????  Conrad Stanley
constanley@juno.com


From owner-software@net.bio.net Wed Jul 14 21:04:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!cyclone.mbnet.mb.ca!canopus.cc.umanitoba.ca!not-for-mail
From: Brian Fristensky <frist@cc.umanitoba.ca>
Newsgroups: bionet.software
Subject: Re: Q: free restriction analysis software
Date: Wed, 14 Jul 1999 16:58:12 -0500
Organization: University of Manitoba
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Markus Hoenicka wrote:
> 
> I'd like to have a simple tool for restriction analysis, i.e I feed
> a sequence file to it and a list of restriction enzymes, and the tool
> tells me the number and location of the restriction sites, the length
> of the released fragments etc.
> 
> It should run on Windows NT, but console applications, incl ANSI C Unix
> source code, and perl scripts are actually preferred.
> 
> Is anyone aware of such a thing?
> TIA
> Markus
> --

The FSAP package includes text-based interactive programs
for restriction site searches which either let you type
in the name and sequence for one restriction enzyme at a 
time (INTREST) or read in a restriction recognition sequence
file (eg. REBASE) for a batch search (BACHREST):

http://www.umanitoba.ca/afs/plant_science/UNIX/doc/fsap/rest.asc

INTREST and BACHREST correctly handle circular sequences, 
and tell you the termini, based on known cutting
sequences. BACHREST can also be run from Steven Smith's
GDE interface.

One of the nice features of INTREST and BACHREST is that
IUPAC-IUB ambiguity codes can even appear in the target
sequence. In addition to letting you to search for cutting
sites in things like consensus sequences or sequences with
ambiguities, you can build model sequences that are 
composites of known sequence, N's, and known restriction 
sites. For example,

GGATCCCTGGATAGGAATCNNNNNNNNNNNNNNNNNNGANTCNNNNNNNNNNNNNNNGATTCCTAG

would give you an output correctly showing the Hinf1 (GANTC)
fragments. This approach is often useful if you have
a construct for which the vector sequence is known, but
some or all of the insert sequence is unknown. The
insert can be simulated by a combination of N's and 
restriction sites, which lets you predict the fragments
you should see on a gel.

DIGEST reads in output files produced by BACHREST, and lets
you perform multiple enzyme digests, either partial or 
complete. Again, BACHREST gives you a table listing fragment
sizes, and cutting enzymes and positions of cuts for termini.

http://www.umanitoba.ca/afs/plant_science/UNIX/doc/fsap/digest.asc

C-source code or Sun/Solaris binaries for the FSAP package
are available at:

http://home.cc.umanitoba.ca/~psgendb/FSAP.html

An old MS-DOS version is also available.

-- 
===========================================================================
Brian Fristensky                |   ... because computer vendors look at
Department of Plant Science     |   higher education as a potentially
University of Manitoba          |   huge revenue source ... there would
Winnipeg, MB R3T 2N2  CANADA    |   ultimately be only five universities
frist@cc.umanitoba.ca           |   worldwide - and they would be
Office phone:   204-474-6085    |   Microsoft, Disney... you get the
FAX:            204-261-5732    |   picture.
http://home.cc.umanitoba.ca/~frist/     Wendy Grossman, Sci. Am. July
1999
===========================================================================

From owner-software@net.bio.net Wed Jul 14 22:16:00 1999
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From: Klaus Schnack <ks@sfb313.uni-kiel.de>
Newsgroups: bionet.software
Subject: Prog. for shade matrix from species-station table
Date: Tue, 13 Jul 1999 00:28:46 +0200
Organization: Rechenzentrum der Universitaet Kiel, Germany
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Hi,

to examine species distributions I'm looking for a program
to create a shade-matrix from a species-station table,
i.e. to replace each count in the table with a symbol whichs
size (or shade) is proportional to the value.

It's a common procedure to compare species distribution
between different sites, but until now I didn't find a
handy tool for this task.

Any suggestion where to find such a tool would be
appreciated very much.

Thanks

Klaaus

                                  '''
                                 (0 0)
---------------------------oOO----(_)----OOo----------------------------
Klaus Schnack                                      ks@sfb313.uni-kiel.de
Institut fuer Polaroekologie
Wischhofstr. 3, Geb. 12
24148 Kiel, Germany
------------------------------------------------------------------------

From owner-software@net.bio.net Wed Jul 14 22:19:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!remarQ73!supernews.com!remarQ.com!remarQ69!WReNclone!WReNphoon3.POSTED!WReN!not-for-mail
From: Klaus Schnack <wrobeli@hotmail.com>
Newsgroups: bionet.software
Subject: Req: Prg. for shade matrix
Organization: http://www.remarq.com: The World's Usenet/Discussions Start Here
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Hi,

to examine species distributions I'm looking for a program
to create a shade-matrix from a species-station table,
I.e. to replace each count in the table with a symbol whichs
size (or shade) is proportional to the value.

It's a common procedure to compare species distribution
between different sites, but until now I didn't find a
handy tool for it.

Any suggestion where to find such a tool would be
appreciated

Thanks

Klaus Schnack

wrobeli(no spam)hotmail.com




**** Posted from RemarQ - http://www.remarq.com - Discussions Start Here (tm) ****

From owner-software@net.bio.net Thu Jul 15 07:11:00 1999
Path: biosci!pravda.ucr.edu!awabi.library.ucla.edu!128.32.206.55!newsfeed.berkeley.edu!oleane!jussieu.fr!saphir.jouy.inra.fr!lindenb
From: lindenb@jouy.inra.fr (Pierre Lindenbaum)
Newsgroups: bionet.software
Subject: Re: Q: free restriction analysis software
Date: 15 Jul 1999 07:44:48 GMT
Organization: INRA
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: Markus Hoenicka wrote:
: > 
: > I'd like to have a simple tool for restriction analysis, i.e I feed
: > a sequence file to it and a list of restriction enzymes, and the tool
: > tells me the number and location of the restriction sites, the length
: > of the released fragments etc.
: > 

Here is a description of my online program called 'CloneIt'.
I hope it will help you...

	Pierre LINDENBAUM

------------------------------------------------------------------------------


     _________________________________________________________________

                                    CLONEIT(tm)
                                  ONLINE VERSION

   A WEB BASED INTERFACE FINDING SUB-CLONING STRATEGIES, IN-FRAME DELETIONS
         AND FRAMESHIFTS USING RESTRICTION ENZYMES AND DNA POLYMERASES.

	        http://topaze.jouy.inra.fr/cgi-bin/CloneIt/CloneIt	

     _________________________________________________________________


 What is CloneIt ?


The use of plasmid vectors in cloning strategies is the basis of any
molecular biologist repertoire. Efficiency is essential and requires the
use of the most appropriate restriction enzymes choices for the desired
application. Selection of those enzymes remains a skill. Several points
that merit consideration include (1) the enzymes characteristics, (2)
location of the restriction sites within the sequence, (3) complementarity
of protuding ends, (4) possible self ligation, (5) use of modifying DNA
polymerase generating blunt ends, (6) in frame cloning constraints,(7) use
of partial digestions and (8) the creation of a stop codon at the ligation
site. This exercise is labor intensive, even with the help of the
classical DNA analysis softwares. These programs typically facilitate
localizing restriction sites in a plasmid sequence;  however it is
impossible to examine all restriction sites and /or combinations then, a
simple cloning strategy may be over-looked as a result of incomplete or
inadequate searching. 

CloneIt Online was created in order to quickly find cloning 
strategies (including sub-cloning, in-frame deletions and frameshifts) 
while controlling the problems described above.

CloneIt Online is available at the following URL: 

        http://topaze.jouy.inra.fr/cgi-bin/CloneIt/CloneIt	

----------------------------------------------------------------------------
  Samples
----------------------------------------------------------------------------
SubCloning
............................................................................

CloneIt V1.0 has found a solution:

 Digest VECTOR with EcoRI [G^AATTC] (878) and Sal I [g^tcgac] (894).

 5'  --G.CCG.G/AA.TT C.CCG.GGG.ATC.CG/T.CGA. CCT.GCA.GCC.AAG--  3'
 3'  --C.GGC.C TT.AA/G.GGC.CCC.TAG.GC A.GCT./GGA.CGT.CGG.TTC--  5'
 NH2     P   E    F    P   G   I   R    R   P    A   A   K   .COOH

Digest first with EcoRI .Then treat with Klenow DNA polymerase.
Finally digest with Sal I .

 Digest INSERT with Sca I [AGT^ACT] (1034) and Sal I [g^tcgac] (3605).

 5' --AT.AAA.GT/ A.CTT.TCA.AAG.AAA.G-- --TA.GAG./TCG.A CC.TGC.AGG.CAT.G-- 3'
 3' --TA.TTT.CA/ T.GAA.AGT.TTC.TTT.C-- --AT.CTC. AGC.T/GG.ACG.TCC.GTA.C-- 3'
 NH2     K   V     L   S   K   K   E -  --  E   S    T    C   R   H   A .COOH

Treat with T4 DNA polymerase.

Sites wil be in frame ligated in 5'.

The first stop codon detected BEFORE the EcoRI site (878) is localized at
position 428 on vector. The first stop codon detected AFTER the Sca I
site (1034) is localized at position 3558 on insert.

Digestion post-ligation:  no enzyme was found.

.......................................................................
        Finding in-frame deletions
.......................................................................

 CloneIt has found an in-frame deletion:

  Digest INSERT with Bcl I [t^gatca] (1427) and PstI [CTGCA^G] (3611).

5'  --TG.TAT./GAT.C AG.GTT.CTT.ACT.G--  --CG.ACC. TGC.A/GG.CAT.GCA.AGC.T-- 3'
3'  --AC.ATA. CTA.G/TC.CAA.GAA.TGA.C--  --GC.TGG./ACG.T CC.GTA.CGT.TCG.A-- 5'
NH2      Y   D    Q    V   L   T   E --  --  T   C    R    H   A   S   F .COOH

 Treat with T4 DNA polymerase.

  Cloning boxes boundaries :[880-1155] [3359-3634].
        Original: 5' ================================================ 3'
        Deletion: 5' =========......................................= 3'
        Equivalent to a  deletion of 728 amino acids [79 %]

Digestion post-ligation: BamHI Sal I Acc I Nsi I .

The first stop codon detected AFTER the PstI site (3611) is localized at
position 3639 on insert.

Translated truncated sequence:...
NSSSVPGAIKGSMAYRKRGARREANINNNDRMQEKDDEKQDQNNRMQLSDKVLSKKEEVV
TDSQEEIKIADEVKKSTKEESKQLEVLKTKEEHQKEIQYEILQKTIPTFEPKESILKKLE
DIKPEQAKKQTKLFRIFEPRQLPIYRANGEKELRNRTYTKLKKDTLPGDYDVREYFLNLY
DR----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--HASFCS...

.........................................................................
Finding frameshifts in INSERT.
.........................................................................

CloneIt  has found an Enzyme that could induce frameshift.

  Digest INSERT with AccI [gt^mkac] (1659).

  5'  --.ATC.AGT.//AT  A.CAC.ATA.AAT.GAT--  3'
  3'  --.TAG.TCA.  TA//T.GTG.TAT.TTA.CTA--  5'
  NH2    I   S   I       H   I   N   D   .COOH

Treat with Klenow DNA polymerase.
Beware : AccI [1 partial site] .

After digestion, fill-in and ligation:

  5'  .ATC.AGT.ATA.TAC.ACA.TAA.ATG 3'
  3'  .TAG.TCA.TAT.ATG.TGT.ATT.TAC 5'
  NH2  I   S   I   Y   T   *   M        COOH

        ¥ FrameShift (+ 2)
        ¥ 2 bases Added.
        ¥ Site is NOT reconstitued after ligation.
        ¥ [51 %] percentage of Insert.
        FIGURE:
                =========================
                                        | (+2)
                                        ===========================

Translated sequence:...EFELGTRGSMATFKDACYHYKRLNKLNSLVLKLGANDETRPAPMTKYKGTCL
YTNLTYCRGCALYHVCQTCSQYNRCFLDEEPHLLRMRTFKDVVTKEDIEGLLTMYETLFPINEKLVNKFINSVKQ
EYLLETYNHLLMPITLQALTINLEDNVYYIFGYYDCMEHENQTPFQFINLLEKYDKLLLDDRNFHRMSHLPVILQ
RYFSKSRFLSKGKKRLSRSDFSDNLMEDRHSPTSLMQVVRNCISiyT*...

............................................................................
Informations
............................................................................


Get information about Bst1107 I

INSERT Pattern
--------------
Bst1107I [GTA^TAC] (1659) p5_1 digestion.
 1 4652 pb      Bst1107I  1744 - Bst1107I  1659
 2 85 pb        Bst1107I  1659 - Bst1107I  1744
...........................................................................
.
 Prototype                :SnaI
 Microorganism            :Bacillus stearothermophilus RFL1107
 Source                   :A.A. Janulaitis
 Methylation site         :
 Commercial availability  :
        Angewandte Gentechnologie Systeme
        Fermentas AB
        Takara Shuzo Co. Ltd.
        Boehringer-Mannheim
 New England Biolabs Refs :457
.........................................................................
Looking for Isoschizomers. (*):Commercialy available)
        ( ) BspM90I  GTA^TAC.
        (*) BssNAI  GTA^TAC.
             also available at:
                        SibEnzyme Ltd.
        ( ) BstBSI  GTA^TAC.
        (*) BstZ17I  GTA^TAC.
             also available at:
                        New England BioLabs
        ( ) XcaI  GTA^TAC.

...........................................................................
Restriction Map
...........................................................................

                                     SACI   SALI
                               ECORI :      hincii
   styi                        acsi  :      acci         ECO52I
   NCOI                   alwi :     ECL136II            eaei
   bstdsi                xhoii :     bsp1286i            bsh1285i
MSCI           xmni      BAMHI :     banii  :           NOTI
eaei    ecorv  : vspi    alwi  :     alw21i :     HINDIII:
:  :    :      : :       ::    :     :      :     :     ::
TGGCCATGGATATCGGAATTAATTCGGATCCGAATTCGAGCTCCGTCGACAAGCTTGCGGCCGCA \ 5266
    ¥         ¥         ¥         ¥         ¥         ¥         ¥  \
ACCGGTACCTATAGCCTTAATTAAGCCTAGGCTTAAGCTCGAGGCAGCTGTTCGAACGCCGGCGT   \ 5330
T  P  T :I  S  E :L  I  R::I  R: I  R: A  P :S  T :S  L :R  P  H  ->
:A :M  D: I  G :I: N  S  D: P  N  S  S  S  V: D  K: L  A::A  A  L ->
: H: G  Y  R  N: *  F  G :S  E :F  E :L  R  R  Q  A  C  G: R  T   ->
: P: V  $  L  R: L  *  A :$  A :*  A :R  P  L  Q  E  F  A: P  T


...........................................................................
Intersections
...........................................................................

                            _______________________________
                            |    VECTOR    |    INSERT    |
                            _______________________________
                            |  IN  |  OUT  |  IN  |  OUT  |
___________________________________________________________
  AatII    [GACGT^C       ] |    0 |    1  |    0 |    1  |
  AccI     [GT^MKAC       ] |    1 |    3  |    1 |    3  |
  AccIII   [T^CCGGA       ] |    0 |    0  |    0 |    0  |
  Acc65I   [G^GTACC       ] |    0 |    1  |    2 |    0  |
  AccBSI   [CCGCTC(-3/-3) ] |    0 |    3  |    0 |    3  |

(...)

  VspI     [AT^TAAT       ] |    0 |    6  |    3 |    6  |
  XbaI     [T^CTAGA       ] |    0 |    0  |    2 |    1  |
  XcmI     [CCANNNNN^NNNNT] |    0 |    2  |    0 |    0  |
  XhoI     [C^TCGAG       ] |    0 |    0  |    0 |    1  |
  XhoII    [R^GATCY       ] |    2 |    7  |    2 |    6  |
  XmaI     [C^CCGGG       ] |    1 |    0  |    1 |    0  |
  XmnI     [GAANN^NNTTC   ] |    0 |    4  |    0 |    3  |
___________________________________________________________
                            |  IN  |  OUT  |  IN  |  OUT  |
                            _______________________________
                            |    VECTOR    |    INSERT    |
                            _______________________________


From owner-software@net.bio.net Sat Jul 17 05:01:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!news1.best.com!news3.best.com!nntp1.ba.best.com!not-for-mail
Reply-To: "www.genomejobs.com" <genomik@genomejobs.com>
From: "www.genomejobs.com" <genomik@genomejobs.com>
Newsgroups: bionet.software
Subject: List of Bioinformatics jobs available listed at www.genomejobs.com 7/16/99
Date: Fri, 16 Jul 1999 22:39:25 -0700
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