From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  2 18:08:33 2000
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From: lisa_crawford@cmagroup.com
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Subject: Washington; Sr. Software Engineer; Medical Imaging, OpenGL, DirectX, graphics, PC Video,
Organization: Career Marketing Associates
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Seattle, Washington; Sr. Software Engineer; OpenGL, DirectX, graphics, 
PC Video, multimedia

-Title: Senior Software Engineer
-Location: Seattle, WA 
-Salaried ($60-85,000), Excellent Benefits   (relocation assistance offered 
by client)  


This professional will perform the software requirements analysis, design, 
and implementation for the next generation medical imaging graphics sub-
system. The subsystem will profide services to synchronize, capture, and 
playback (multiple streams) of both uncompressed and compressed video 
and audio in realtime. 

Be familiar with multimedia solutions which are commercially available 
and with developing custom solutions. Implement and maintain requirements 
and design documentation. Devise automated and manual tests for regression 
and new feature testing. 

Requirements: 

Software development experience in C/C++ in a PC/NT environment. Should 
have experience with DirectX, OpenGL, and PC multimedia application development. 
Understanding of interrupts, DMA, queues, stacks, shared memory, and serial 
and parallel I/O design. Experience with emulators, symbolic debuggers, 
and/or simulation tools. Familiarity with test equipment: logic analyzers, 
oscilloscopes, and DVMs. Experience developing scalable software systems 
is a plus.

Strong Software Engineering Background. Thorough knowledge of embedded 
software/hardware systems, and Object Oriented design. Experience developing 
multimedia applications on Win95/98/NT. Expertise in real-time software 
design and programming in embedded systems. Good hardware/software diagnostic 
and debugging skills. Able to characterize problems quickly. Versatile, 
proactive, self-starter. Able to quickly and independently learn and apply 
new skills. Able to work from very general requirements. Enjoys and thrives 
on a wide variety of programming and organizational activities. 

Good verbal and written communication skills. A team player who will cooperate 
and collaborate with other engineers to produce an optimum solution. Demonstrates 
an understanding of the Software Life Cycle, and sound SW Engineering 
practices.

Please refer to JO# 11278RJS in your response.

lisa_crawford@cmagroup.com 

Lisa Crawford
Sr. Researcher & Associate Recruiter
ljc@cmagroup.com
IT & Software Solutions Team
Career Marketing Associates



From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  2 21:40:29 2000
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From: lisa_crawford@cmagroup.com
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Subject: Colorado; Sr. Software Engineer; NT, C++, DICOM, Imaging
Organization: Career Marketing Associates
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Colorado; Sr. Software Engineer; NT, C++, DICOM, Imaging

**We are also working similar medical imaging software positions for clients 
in NE USA, Midwest, PNW, Texas, CA and BC Canada.  

-Senior Software Engineer
-Greater Denver/Boulder
-Salaried, Full-Time, Excellent Benefits 
(Relocation Assistance Available)

Medical DICOM knowledge important. 
Experience with C/C++ and NT required. 
Image manipulation, compression, edge detection, analysis, all good things 
to have. 

Please refer to JO# 7657RJS in your response.

lisa_crawford@cmagroup.com 

Lisa Crawford
Sr. Researcher & Associate Recruiter
ljc@cmagroup.com
IT & Software Solutions Team
Career Marketing Associates



From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  2 21:44:54 2000
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From: lisa_crawford@cmagroup.com
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Subject: Washington; Software Engineer; Medical Imaging, NT,C++,MFC
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Seattle, Washington;  Software Engineer; NT,C++,MFC
-Title:Software Engineer
-Location: Seattle, WA 
-Salaried, Good Benefits 
(relocation assistance offered by client)  

NT software engineer to work with senior image processing engineer on 
embedding 3D.

Attributes:
(1) 1+ years NT Visual C++ experience.
(2) Very important! - Self starter/proactive/energetic.
(3) Knowledge of Microsoft MFC,STL,ATL,ActiveX,DirectX,COM.
(4) OOD/OOA.
(5) Image processing experience would be a plus but would settle for someone 
who has willingness to learn.

Will consider a MSCS/MSEE right out of school if the right person.

Please refer to JO# 9749RJS in your response.

lisa_crawford@cmagroup.com 

Lisa Crawford
Sr. Researcher & Associate Recruiter
ljc@cmagroup.com
IT & Software Solutions Team
Career Marketing Associates



From owner-bio-software@hgmp.mrc.ac.uk  Mon Jan  3 14:35:35 2000
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From: Josep Francesc Abril Ferrando <jabril@imim.es>
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Subject: GFF2PS Released...
Date: Mon, 03 Jan 2000 13:44:15 +0100
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               ------ ANNOUNCING GFF2PS ------

    gff2ps is a program for visualizing annotations of genomic sequences.
The program takes as input the annotated features on a genomic sequence
in GFF format, and produces a visual output in PostScript. It can be used
in a very simple way, because it assumes that the GFF file itself carries
enough formatting information. It also allows through a number of options
and/or a configuration file, for a great degree of customization.

    gff2ps v0.93 has been released, this version is fully operative,
handling unsorted GFF-records, multiple media sizes, and vertical pagination.
A complete user's manual explaining how to use gff2ps is included in the tar
file, which contains few examples too.

You can download it from our ftp server:

    ftp://www1.imim.es/pub/gff_tools/gff2ps/

or visit gff2ps homepage:

 http://www1.imim.es/~jabril/GFFTOOLS/GFF2PS.html

which is also available following the GFF2PS link from my home page:

 http://www1.imim.es/~jabril/

---

JOSEP FRANCESC ABRIL FERRANDO

Institut Municipal d'Investigació Mèdica
GENOME INFORMATICS GROUP
C/ Dr. Aiguader 80
08003 - Barcelona (SPAIN)
Ph:  +34 93 2211009 ext 2016
Fax: +34 93 2213237

http://www1.imim.es/~jabril




From owner-bio-software@hgmp.mrc.ac.uk  Mon Jan  3 18:39:17 2000
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From: rph@cse.ucsc.edu (Richard Hughey)
X-Newsgroups: bionet.software
Subject: SAM HMM Software Version 3.0
Date: 3 Jan 2000 18:39:08 GMT
Organization: UC Santa Cruz CIS/CE
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            We are pleased to announce release of UCSC's

		  SAM Version 3.0 with SAM-T99

	 http://www.cse.ucsc.edu/research/compbio/sam.html


The Sequence Alignment and Modeling system (SAM) is a collection of
flexible software tools for creating, refining, and using linear
(profile) hidden Markov models for biological sequence analysis.  The
model states can be viewed as representing the sequence of columns in
a multiple sequence alignment, with provisions for arbitrary
position-dependent insertions and deletions in each sequence.  The
models are trained on a family of protein or nucleic acid sequences
using an expectation-maximization algorithm and a variety of
algorithmic heuristics.  A trained model can then be used to both
generate multiple alignments and search databases for new members of
the family.

For the first time, SAM includes scripts for the SAM-T99 method of
remote homology detection.  SAM-T99 is an iterative HMM search method
for creating an HMM from a single protein sequence or seed alignment
using iterative search of a protein database.  The method is currently
the most sensitive purely-sequence-based remote homology detection
algorithm [Park et al, JMB 284(4):1201-1210,1998].  SAM-T99 is based
on successful methods created for the CASP2 and CASP3 protein
structure prediction experiments [Karplus et al, Proteins,
Sup.1:134-139,1997 and Sup.3:121-125,1999].

Other additions include the use of reverse-sequence null models
[Barrett et al, Bioinformatics 14(10):846-856,1998], the calculation
of E-values, and constrained alignment and training.

SAM is available in binary distribution for unix, linux, and freebsd
platforms.

SAM is FREE for academic and non-profit use, but requires a signed
hardcopy license agreement if you do not already have one.  The
license agreement is available from the WWW site.

The license agreement, papers, documentation, and more information on
SAM can be found at:

    http://www.cse.ucsc.edu/research/compbio/sam.html


Servers for performing SAM-T98 structure prediction (SAM-T99 to
available soon) using our library of HMMs is available at:

   http://www.cse.ucsc.edu/research/compbio/HMM-apps/HMM-applications.html


The server will soon be accelerated with the UCSC Kestrel parallel processor: 

   http://www.cse.ucsc.edu/research/kestrel




Kevin Karplus
Mark Diekhans
Richard Hughey

saminfo@cse.ucsc.edu

Department of Computer Engineering
University of California
Santa Cruz, CA 95064


From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 10:25:06 2000
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From: "Simon Dray" <simon.dray@bbsrc.ac.uk>
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Subject: test
Date: Tue, 4 Jan 2000 10:10:17 -0000
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test message please ignore




From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 10:38:18 2000
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From: olam@radium.uio.no (Ola Myklebost)
X-Newsgroups: bionet.software
Subject: Post doc position in Norway: Data Mining/Bioinformatics
Date: Tue, 04 Jan 2000 11:38:12 +0100
Organization: Norwegian Radium Hospital
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A three year post doc position is available at the Microarray Centre
at the Institute for Cancer research / Norwegian Radium Hospital in
Oslo, Norway.

We are preferably looking for a computer scientist or
bioinformatician, but are also interested in molecular biologists
with some competence in bioinformatics or computer science.
Experience with microarrays will be an advantage.

Please look at http://www.med.uio.no/dnr/microarray/postdoc.html


Ola Myklebost, Professor, Dr Philos       University of Oslo

Dept of Tumor Biology             Tel (Office):   +47-2293-4299 (-5936)
Institute for Cancer Research     Switchboard:    +47-2293-4000
The Norwegian Radium Hospital     Fax:            +47-2252-2421
Montebello                        Pager:          +47-9681-8125
N-0310 OSLO, Norway               Email (org): ola.myklebost@labmed.uio.no
                                  or (machine address): olam@radium.uio.no

WWW presentation: http://www.med.uio.no/dnr/People/Ola.html


From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 13:50:11 2000
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From: "Harold Drabkin" <hdrabkin@user1.channel1.com>
X-Newsgroups: bionet.software
Subject: excel add-in
Date: Tue, 4 Jan 2000 08:46:39 -0500
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Some time ago, I saw an add-in or program that essentially aided using excel
for scientific charting, etc.; some sort of collection of macros, templates,
etc. I'm now using excel 2000.  Does anyone have a lead on such a thing?




From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 15:22:39 2000
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From: "Claude Jakob" <Jakob@micro.biol.ethz.ch>
X-Newsgroups: bionet.software
Subject: Looking for Cloning Software
Date: Tue, 4 Jan 2000 16:25:12 +0100
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This is a multi-part message in MIME format.

------=_NextPart_000_002B_01BF56D0.46BD9880
Content-Type: text/plain;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable

Hi,

I am currently looking for (evaluating) DNA cloning software (e.g. for =
manipulation of plasmids and fragments with correct terminior in silica =
cloning , such as Clone Manager) for our PC platform. Apart from "Clone =
Manager" I did not find very much in the field.=20

If anybody could provide me with information of other cloning programs =
(Windows 95/98/NT) I would be very grateful.

Thanks,Claude

-----------------------------------------------------------------------
Claude A. Jakob, Ph.D.
Institute for Microbiology, ETH Zuerich
Schmelzbergstrasse 7
CH-8092 Zuerich
Switzerland
=20
Phone: +41-1-632-3327
Fax:      +41-1-632-1148
email:  jakob@micro.biol.ethz.ch
www:   http://www.micro.biol.ethz.ch/~jakobc

------=_NextPart_000_002B_01BF56D0.46BD9880
Content-Type: text/html;
	charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META content=3D"text/html; charset=3Diso-8859-1" =
http-equiv=3DContent-Type>
<META content=3D"MSHTML 5.00.2919.6307" name=3DGENERATOR>
<STYLE></STYLE>
</HEAD>
<BODY>
<DIV><FONT size=3D2>Hi,</FONT></DIV>
<DIV>&nbsp;</DIV>
<DIV><FONT size=3D2>I am currently looking for (evaluating) DNA cloning =
software=20
(e.g. for manipulation of plasmids and fragments with correct terminior =
<EM>in=20
silica </EM>cloning , such as Clone Manager) for&nbsp;our PC platform. =
Apart=20
from "Clone Manager" I did not find very much in the field. =
</FONT></DIV>
<DIV>&nbsp;</DIV>
<DIV><FONT size=3D2>If anybody could provide me with information of =
other cloning=20
programs (Windows 95/98/NT) I would be very grateful.</FONT></DIV>
<DIV>&nbsp;</DIV>
<DIV><FONT size=3D2>Thanks,</FONT><FONT size=3D2>Claude</FONT></DIV>
<DIV><BR><FONT=20
size=3D2>----------------------------------------------------------------=
-------<BR>Claude=20
A. Jakob, Ph.D.<BR>Institute for Microbiology, ETH =
Zuerich<BR>Schmelzbergstrasse=20
7<BR>CH-8092 Zuerich<BR>Switzerland<BR>&nbsp;<BR>Phone:=20
+41-1-632-3327<BR>Fax:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;=20
+41-1-632-1148<BR>email:&nbsp; </FONT><A=20
href=3D"mailto:jakob@micro.biol.ethz.ch"><FONT=20
size=3D2>jakob@micro.biol.ethz.ch</FONT></A><BR><FONT =
size=3D2>www:&nbsp;&nbsp;=20
</FONT><A href=3D"http://www.micro.biol.ethz.ch/~jakobc"><FONT=20
size=3D2>http://www.micro.biol.ethz.ch/~jakobc</FONT></A></DIV></BODY></H=
TML>

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From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 16:01:14 2000
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From: Przemko Tylzanowski <przemko@med.kuleuven.ac.be>
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Subject: Merging bright fiels and fluorescence
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<!doctype html public "-//w3c//dtd html 4.0 transitional//en">
<html>
Hi!
<br>We have a SPOT camera system and a software that comes with it. Unfortunately
the software (as good as it is) cannot merge bright field and fluorescence
images (for instance Nomarski with CY2).
<br>Is anyone of you aware of a software that could do that?
<br>TIA
<br>Przemko
<p>--
<br>Przemko Tylzanowski Ph.D.
<br>LSD &amp; Joint
<br>O &amp; N
<br>University of Leuven
<br>Herestraat 49
<br>3000 Leuven
<br>Belgium
<p>phone: (32-16)34-61-96
<br>fax&nbsp; : (32-16)34-62-00
<br>&nbsp;</html>



From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 16:05:15 2000
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From: "Soeren W. Rasmussen" <swr@crc.dk>
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--------------E858269DC9B68F5F21AA0FE6
Content-Type: text/plain; charset=iso-8859-1
Content-Transfer-Encoding: 8bit

DNATools has some fairly simple options for building plasmids on the
basis of restriction enzyme digests. If you wish to try it, a fully
functional, free demo copy can be downloaded from our homepage .

Regards

Soeren

Claude Jakob wrote:

> Hi, I am currently looking for (evaluating) DNA cloning software (e.g.
> for manipulation of plasmids and fragments with correct terminior in
> silica cloning , such as Clone Manager) for our PC platform. Apart
> from "Clone Manager" I did not find very much in the field. If anybody
> could provide me with information of other cloning programs (Windows
> 95/98/NT) I would be very grateful. Thanks,Claude
>
> ----------------------------------------------------------------------
>
> Claude A. Jakob, Ph.D.
> Institute for Microbiology, ETH Zuerich
> Schmelzbergstrasse 7
> CH-8092 Zuerich
> Switzerland
>
> Phone: +41-1-632-3327
> Fax:      +41-1-632-1148
> email:  jakob@micro.biol.ethz.ch
> www:   http://www.micro.biol.ethz.ch/~jakobc

--
Dr. scient. Søren W. Rasmussen
Carlsberg Laboratory, Department of Physiology
10 Gl. Carlsbergvej, DK-2500, Copenhagen, Denmark
Phone  45 33275230/45 36162259, Fax 45 33274766
swr@crc.dk, http://www.crc.dk/phys/

DNATools sequencing software:
http://www.crc.dk/phys/dnatools.htm


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<!doctype html public "-//w3c//dtd html 4.0 transitional//en">
<html>
DNATools has some fairly simple options for building plasmids on the basis
of restriction enzyme digests. If you wish to try it, a fully functional,
free demo copy can be downloaded from our homepage .
<p>Regards
<p>Soeren
<p>Claude Jakob wrote:
<blockquote TYPE=CITE><style></style>
<font size=-1>Hi,</font> <font size=-1>I
am currently looking for (evaluating) DNA cloning software (e.g. for manipulation
of plasmids and fragments with correct terminior <i>in silica </i>cloning
, such as Clone Manager) for our PC platform. Apart from "Clone Manager"
I did not find very much in the field.</font> <font size=-1>If anybody
could provide me with information of other cloning programs (Windows 95/98/NT)
I would be very grateful.</font> <font size=-1>Thanks,Claude</font>
<br><font size=-1>-----------------------------------------------------------------------</font>
<br><font size=-1>Claude A. Jakob, Ph.D.</font>
<br><font size=-1>Institute for Microbiology, ETH Zuerich</font>
<br><font size=-1>Schmelzbergstrasse 7</font>
<br><font size=-1>CH-8092 Zuerich</font>
<br><font size=-1>Switzerland</font>
<p><font size=-1>Phone: +41-1-632-3327</font>
<br><font size=-1>Fax:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; +41-1-632-1148</font>
<br><font size=-1>email:&nbsp; <a href="mailto:jakob@micro.biol.ethz.ch">jakob@micro.biol.ethz.ch</a></font>
<br><font size=-1>www:&nbsp;&nbsp; <a href="http://www.micro.biol.ethz.ch/~jakobc">http://www.micro.biol.ethz.ch/~jakobc</a></font></blockquote>
--
<br>Dr. scient. S&oslash;ren W. Rasmussen
<br>Carlsberg Laboratory, Department of Physiology
<br>10 Gl. Carlsbergvej, DK-2500, Copenhagen, Denmark
<br>Phone&nbsp; 45 33275230/45 36162259, Fax 45 33274766
<br>swr@crc.dk, <A HREF="http://www.crc.dk/phys/">http://www.crc.dk/phys/</A>
<p>DNATools sequencing software:
<br><A HREF="http://www.crc.dk/phys/dnatools.htm">http://www.crc.dk/phys/dnatools.htm</A>
<br>&nbsp;</html>

--------------E858269DC9B68F5F21AA0FE6--



From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan  4 19:26:26 2000
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From: Andrew Rambaut <andrew.rambaut@zoo.ox.ac.uk>
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Subject: New tree manipulation program.
Date: Tue, 04 Jan 2000 17:58:51 +0000
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I would like to announce the first, highly preliminary, alpha version
of my new tree manipulation package. TreeEdit is an application for
organising, viewing and manipulating sets of phylogenetic trees. It is
intended as a tool for preparing sets of trees for use in phylogenetics
packages such as PAUP. 

Runs on Macintosh (PowerMacs) under MacOS 8.5 or above (actually
only tested on 8.5 and above may work on previous systems).

<http://evolve.zoo.ox.ac.uk/TreeEdit/TreeEdit.html>

Features

*  The import and export of trees in a range of commonly used formats.
These include PHYLIP (NEWICK), NEXUS (PAUP and MacClade) and CAIC
formats. 
*  Full drag-and-drop of trees between windows, to the desktop as a
"clipping" or to text editors. In the case of the latter two options,
the trees are written as a NEXUS file. 
*  Cut and Pasting of trees between TreeEdit and text editors (again
the trees are written as a NEXUS file). They can be pasted directly
into PAUP. 
*  Root the tree by clicking on the branch (or node) on which you wish
the root to lie. Midpoint rooting is also available. 
*  Include and exclude taxa or clades. Excluded branches are drawn as
"greyed-out" or can be hidden altogether. Trees can be written without
the excluded taxa. 
*  Edit taxon labels. 
*  Rotate branch order at a node. 
*  Drag and drop editing of branches. 
*  Collapse branches to produce polytomies. 
*  Randomly resolve polytomies. 
*  A set of trees can be "linked" so that an operation done on one is
performed on all the others (if possible). This option is limited to a
few operations at present. 


------------------------------------------------------------------------

The following features are still to be implemented:


*  Er.. lots - please feel free to suggest some more. 
*  The name might even be improved.

------------------------------------------------------------------------

Andrew


From owner-bio-software@hgmp.mrc.ac.uk  Wed Jan  5 21:35:02 2000
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From: Roland Hubner <rhubner@hgins.uia.ac.be>
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Happy New Year Przemko!

> cannot merge bright field and fluorescence images (for instance Nomarski
> with CY2).
...
> LSD; Joint

 I would rather suggest contacting www.biotech.missouri.edu/mcc/mccf.html

Have fun,
 Roland


From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 07:50:18 2000
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From: mhabio@my-deja.com
X-Newsgroups: bionet.software
Subject: ANN: Fermentor Control Software version 2.0
Date: Thu, 06 Jan 2000 07:40:10 GMT
Organization: Deja.com - Before you buy.
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Version 2.0 of the Control Software for the BioStat Fermentors has been
released. (Freeware)

Version 2.0 has several new features like Timed Events and Profiles,
Fuzzy Logic Substrate Control, and Internet Client is available. Program
works with Biostat A, B, C, D, Micro-DCU, & DCU.

The BioStat control program collects process data and display them in a
graphical window. All process set points are controlled by graphical
sliders or by keyboard, and numerical displays show the current
settings. Intelligent control to master substrate addition is possible
with the fuzzy logic control module. Timed events/profiles can be
designed with the profile editor. Finally, a TCP/IP client makes it
possible to control the unit from any online computer in the world.

Please find more information and screen shots on the BioStat Control
Software homepage: http://imsb.au.dk/~mha/biohome.htm

--
Regards,
Mikkel H. Andersen



Sent via Deja.com http://www.deja.com/
Before you buy.


From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 14:00:15 2000
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From: gbottu@bigben.vub.ac.be (Guy Bottu)
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Subject: where can I get recent elm/mm ?
Date: 6 Jan 2000 13:53:19 GMT
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I have a question. Where can I find the most recent version of the mail
client elm ? Version 2.4.25 is not Y2K compliant. It sends messages with
the year 100 in the date. I have seen that there exists a version 2.5
that does not have this bug. However, at the anonymous ftp site
nic.funet.fi the last available version is 2.4.25.

Is there also a version of mm (MetaMail) beyond 2.7 ? Version 2.7 does
not compile under Solaris.

	Thank you in advance,
	  Guy Bottu,
	Belgian EMBnet Node


From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 15:29:19 2000
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From: jkb@mrc-lmb.cam.ac.uk (James Bonfield)
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Subject: Re: where can I get recent elm/mm ?
Date: 6 Jan 2000 15:29:14 GMT
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In article <8526of$4dr$1@mach.vub.ac.be> gbottu@bigben.vub.ac.be (Guy Bottu) writes:
>I have a question. Where can I find the most recent version of the mail
>client elm ? Version 2.4.25 is not Y2K compliant. It sends messages with
>the year 100 in the date. I have seen that there exists a version 2.5
>that does not have this bug. However, at the anonymous ftp site
>nic.funet.fi the last available version is 2.4.25.

Try http://ftpsearch.lycos.com/?form=medium for a good ftp search engine.

Look for elm-2.4ME+66.tar.gz or elm2.5.2.
I prefer 2.4ME (a spin-off of 2.4) as it has better handling of MIME than
2.5.2. Also see the elm newsgroup (I forget what it's called) for a Y2K patch
to 2.5.2, as even that still has some problems.

I used elm until a few days ago, and found the same problem. The
authors of 2.4ME appear to have got fed up with the problems in elm
and so wrote their own from scratch, called Mutt. I'm now using this
and I find it far superior, and very easy to use if you are used to
the elm keybindings. I cannot remember the mutt home page, but I'm
sure a few altavista searches will pick it out.

	James
--
James Bonfield (jkb@mrc-lmb.cam.ac.uk)   Tel: 01223 402499   Fax: 01223 213556
Medical Research Council - Laboratory of Molecular Biology,
Hills Road, Cambridge, CB2 2QH, England.
Also see Staden Package WWW site at http://www.mrc-lmb.cam.ac.uk/pubseq/


From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 15:52:10 2000
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From: Tim Cutts <timc@chiark.greenend.org.uk>
X-Newsgroups: bionet.software
Subject: Re: where can I get recent elm/mm ?
Date: 06 Jan 2000 15:50:10 +0000 (GMT)
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In article <852cca$9j8$1@pegasus.csx.cam.ac.uk>,
James Bonfield <jkb@mrc-lmb.cam.ac.uk> wrote:
>authors of 2.4ME appear to have got fed up with the problems in elm
>and so wrote their own from scratch, called Mutt. I'm now using this
>and I find it far superior, and very easy to use if you are used to
>the elm keybindings. I cannot remember the mutt home page, but I'm
>sure a few altavista searches will pick it out.

I use mutt as well.  It is absolutely superb.

http://www.mutt.org

Tim.



From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 18:16:47 2000
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From: Piotr Kozbial <piotrk@ibb.waw.pl>
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Guy Bottu wrote:
> 
> I have a question. Where can I find the most recent version of the mail
> client elm ? Version 2.4.25 is not Y2K compliant. It sends messages with
> the year 100 in the date. I have seen that there exists a version 2.5
> that does not have this bug. However, at the anonymous ftp site
> nic.funet.fi the last available version is 2.4.25.
> 
> Is there also a version of mm (MetaMail) beyond 2.7 ? Version 2.7 does
> not compile under Solaris.
> 
>         Thank you in advance,
>           Guy Bottu,
>         Belgian EMBnet Node

http://www.uwsg.indiana.edu/y2k/elmy2k.html


From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan  6 19:00:13 2000
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From: Cornelius Krasel <krasel@wpxx02.toxi.uni-wuerzburg.de>
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Subject: Re: where can I get recent elm/mm ?
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James Bonfield <jkb@mrc-lmb.cam.ac.uk> wrote:
> I used elm until a few days ago, and found the same problem. The
> authors of 2.4ME appear to have got fed up with the problems in elm
> and so wrote their own from scratch, called Mutt.

I think elm-2.4ME is still being maintained. I did not experience any
problems with elm-2.4ME62 Y2K- or otherwise. I prefer elm over mutt
because I don't like the design (I guess it's just me...). I agree
with James on elm-2.5.2 :-)

Mutt is available from http://www.mutt.org/ . For some reason the
server is currently very slow.

--Cornelius.

-- 
/* Cornelius Krasel, U Wuerzburg, Dept. of Pharmacology, Versbacher Str. 9 */
/* D-97078 Wuerzburg, Germany   email: phak004@rzbox.uni-wuerzburg.de  SP4 */
/* "Science is the game we play with God to find out what His rules are."  */


From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan  7 13:11:17 2000
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From: "Tim Corp." <station@nursat.kz>
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Subject: Pro AVP anti-virus packet for Win95/98/NT
Date: Fri, 7 Jan 2000 18:41:01 +0600
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From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan  7 19:10:09 2000
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From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
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Subject: Re: where can I get recent elm/mm ?
Date: 7 Jan 2000 18:53:18 GMT
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In article <8526of$4dr$1@mach.vub.ac.be>,
Guy Bottu <gbottu@bigben.vub.ac.be> wrote:
>I have a question. Where can I find the most recent version of the mail
>client elm ? Version 2.4.25 is not Y2K compliant. It sends messages with
>the year 100 in the date. I have seen that there exists a version 2.5
>that does not have this bug. However, at the anonymous ftp site
>nic.funet.fi the last available version is 2.4.25.

We had that problem too.  I found elm 2.5.2 at

    ftp://ftp.virginia.edu/pub/elm/

This solved the Y2K problem.  Note that a RedHat package for it is there too.

-- 
Joe Felsenstein         joe@genetics.washington.edu
 Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA


From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan  7 22:31:36 2000
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From: rgarcia@is05.fas.harvard.edu (Rachel M. Kadel-Garcia)
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Subject: phrap quality scores
Date: 7 Jan 2000 22:15:32 GMT
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Does anyone here have an understanding of phrap quality scores
beyond what's in the docs?  I'm trying to figure out how to 
assign similar quality scores to assemblies not done with phrap,
and I'm resorting to spelunking in the source, but it's rough 
going.

						Rachel


From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan  7 22:55:47 2000
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From: solovyev@sanger.ac.uk (Victor Solovyev)
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Subject: SUPER_LINK_Chromosome 22 Gene Predictions by FGENESH
Date: 7 Jan 2000 22:55:42 -0000
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 Gene Predictions for SUPER_LINK_Chromosome 22 are available at:
             http://genomic.sanger.ac.uk/inf/infodb.shtml
             
            under CGG genomics WEB server:  http://genomic.sanger.ac.uk/    

       
 the predictions by Fgenesh program (Salamov,Solovyev,1999) 
 
 You can ftp data for your further analysis! 
                 
   Chromosome 22 predicted genes and similarity data in INFOGENE format 
   Chromosome 22 predicted proteins in fasta format 
   Chromosome 22 predicted exon sequences in fasta format 
   Chromosome 22 predicted exon amino acid sequences in fasta format 
    
Due to high accuracy exon prediction and significantly less accurate assigning 
exons to a particular gene, exon sequences itself present value to experimental 
gene verification or Other projects 
               
  Visual representation of Predicted genes as well as ALL KNOWN GENES could be 
seen in gene centred database INFOGENE through Java viewer.
    This database includes genes constructed often from many GenBank entries, 
release 114.
	
Divisions with separate collections for model organisms include:

Human genes data
Other Primates genes data
Mus musculus genes data
Other Rodenta genes data
Other Mammalia genes data       
Danio rerio genes data          
Fugu rubripes genes data
Other Vertebrata genes data
Drosophila melanogaster genes data
Caenorhabditis elegans genes data
Other Invertebrata genes data
Saccharomyces cerevisiae genes data 
Schizosaccharomyces pombe genes data
Arabidopsis thaliana genes data
Oriza Sativa genes data				* New
Zea Mays genes data				* New
Other eukaryotes from GB *.pln genes data
Annotation of Drosophila Melanogaster 2.9 MB ADH region
SUPER_LINK Chromosome 22 gene predictions        * New

Included Drosophila melanogaster ADH 2.9 MB genomic region automatic annotation
using FGENES and FGENESH: Fgenes predictions, Fgenesh predictions, CGG1 -
summary prediction using both mention above and std3 - manual annotation based o
nexperimental data (some computational) by Ashburner et al. (1999).
  This example shows problems with genomic annotation: 90% of actual coding
sequences predicted accurately, but exons often combined very different
from real genes.

- You can save an Infogene record using Action menu and Obtain Infogene
locus option (with or without sequence)
- Realized search of context (select Search filds (among many specific
  lines of Infogen database) and print your word in left down corner)
  For example you can find all genes which have start of transcription
  annotated in GeneBank: Select Context in Option menu,
  select onlt TSP field in SearchFilds, put * in search window and Enter.

To see all information about a gene in the locus:
    Put mouse pointer to gene block
   in upper window and push and keep right mouse button
   (shift key + push and click right mouse button will permanently
    show this information)
LocusInfo button will show a head of locus which shows how many GenBank
entries are used for gene description
---


From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan  8 02:10:11 2000
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From: "Stephen R. Lasky" <srlasky@cellworks.mbt.washington.edu>
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Subject: Re: phrap quality scores
Date: Sat, 08 Jan 2000 01:54:13 +0000
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"Rachel M. Kadel-Garcia" wrote:
> 
> Does anyone here have an understanding of phrap quality scores
> beyond what's in the docs?  I'm trying to figure out how to
> assign similar quality scores to assemblies not done with phrap,
> and I'm resorting to spelunking in the source, but it's rough
> going.
> 
>                                                 Rachel


Phrap, I believe, is not the program assigning the quality scores. 
Phred is.  Phrap uses the phred quality scores to do its alignments.

Do you have the Phred docs? 

I presume that you don't have the chromats, otherwise you could run them
through phred and get the quality scores.

srlasky
-- 
Stephen R. Lasky, Ph.D.			#
University of Washington		#
Department of Molecular Biotechnology	#
HSB K336a box 357730			#
Seattle, WA, 98195 USA			#
email:	srlasky@u.washington.edu	#
Phone: 	206-616-5865			#
Fax:	206-685-7301			#
#########################################


From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan  8 05:31:25 2000
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From: rgarcia@is06.fas.harvard.edu (Rachel M. Kadel-Garcia)
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Subject: Re: phrap quality scores
Date: 8 Jan 2000 05:14:54 GMT
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In article <387698C5.EEA17FB@cellworks.mbt.washington.edu>, 
Stephen R. Lasky wrote:
>"Rachel M. Kadel-Garcia" wrote:
>> 
>> Does anyone here have an understanding of phrap quality scores
>> beyond what's in the docs?  I'm trying to figure out how to
>> assign similar quality scores to assemblies not done with phrap,
>> and I'm resorting to spelunking in the source, but it's rough
>> going.
>> 
>>                                                 Rachel
>
>
>Phrap, I believe, is not the program assigning the quality scores. 
>Phred is.  Phrap uses the phred quality scores to do its alignments.

Phred assigns quality scores to bases in individual reads.  Phrap uses
those quality scores and various things about the alignments to generate
consensus quality scores.

>Do you have the Phred docs? 
>
>I presume that you don't have the chromats, otherwise you could run them
>through phred and get the quality scores.

I have the phred docs and the chromat files, but that won't get me
consensus quality scores.

						Rachel


From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan  8 18:33:44 2000
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From: shbowp@sdfsdf.com
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Subject: LEGAL C`A`B`L`E TV D`E-S`C`R`A`M`B`L`E`R  5386
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From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan  8 20:20:10 2000
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Send an email with "THE LIST" in the subject line to

auto.program.list@iname.com If not working send To uik87g@writemail.com

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...And we will send you a Full List with just about any Software package
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From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  9 10:36:15 2000
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> I am currently looking for (evaluating) DNA cloning software (e.g. for =
> manipulation of plasmids and fragments with correct terminior in silica =
> cloning , such as Clone Manager) for our PC platform. Apart from "Clone =
> Manager" I did not find very much in the field.=20

Hi Claude,
 you should look at our catalog:

http://www.bioinformatik.de/cgi-bin/browse/Catalog/Software/Windows/

Best regards,
Andrea

-- 
Institut fuer Botanik III
Heinrich-Heine-Universitaet
Universitaetsstr.1         email : webmaster@bioinformatik.de 
40225 Duesseldorf          http://www.bioinformatik.de


From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  9 10:40:59 2000
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hbzh@188.net (Haobin Zhao) writes:

> I am now doing research about gene clone and gene expression, I want a
> software to find the gene promoter.
Look at
http://www.bioinformatik.de/cgi-bin/browse/Catalog/Databases/Regulatory_Regions/

You will find programs for promotor prediction.

Andrea
-- 
Institut fuer Botanik III
Heinrich-Heine-Universitaet
Universitaetsstr.1         email : webmaster@bioinformatik.de 
40225 Duesseldorf          http://www.bioinformatik.de


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--
-----------------------------------------------------------------
                         Moler Inc.
   Software for kids and computer retards!
               http://www.moler.co.uk
-----------------------------------------------------------------




From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  9 19:15:18 2000
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Rachel,

I'm assuming you've got the phred generated sequence and quality files.
>From the limited testing I've done recently, with limited amounts of
overlapping sequence to keep the complexity down, here's the way it
appears to work.

1. If sequence in only one direction, the highest/best score is used.
2. If sequence in both directions, the best qualities from each
direction are added together.

However, this comes with a few caveats. Phrap brings the sequences
together in segments, so the highest quality value mention above is
really the quality value of that base within the segment chosen as the
representative. Also, I haven't quite figured out the quality given to
discordant bases. I haven't bothered digging into the source yet,
though. If I find out anything more, I'll let you know (if you'd like).

-Todd

"Rachel M. Kadel-Garcia" wrote:
> 
> In article <387698C5.EEA17FB@cellworks.mbt.washington.edu>,
> Stephen R. Lasky wrote:
> >"Rachel M. Kadel-Garcia" wrote:
> >>
> >> Does anyone here have an understanding of phrap quality scores
> >> beyond what's in the docs?  I'm trying to figure out how to
> >> assign similar quality scores to assemblies not done with phrap,
> >> and I'm resorting to spelunking in the source, but it's rough
> >> going.
> >>
> >>                                                 Rachel
> >
> >
> >Phrap, I believe, is not the program assigning the quality scores.
> >Phred is.  Phrap uses the phred quality scores to do its alignments.
> 
> Phred assigns quality scores to bases in individual reads.  Phrap uses
> those quality scores and various things about the alignments to generate
> consensus quality scores.
> 
> >Do you have the Phred docs?
> >
> >I presume that you don't have the chromats, otherwise you could run them
> >through phred and get the quality scores.
> 
> I have the phred docs and the chromat files, but that won't get me
> consensus quality scores.
> 
>                                                 Rachel


From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan  9 23:19:04 2000
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From: johns@ks.uiuc.edu (John Stone)
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         VMD "Visual Molecular Dynamics" 1.4 Announcement
         ------------------------------------------------
The Theoretical Biophysics group at the Beckman Institute For Advanced  
Science and Technology, the University of Illinois (U-C), is proud to
announce the public release of VMD 1.4.  VMD is a package for the 
visualization and analysis of biomolecular systems.  This software is
distributed free of charge and includes source code, documentation,
and precompiled binaries for IBM, HP, Linux, Sun, and SGI Unix systems, 
as well as Microsoft Windows 95/98/NT.
The VMD documentation includes an installation guide, a users guide, and a 
programmers guide for interested researchers.  VMD also provides on-line 
help through the use of an external HTML viewer.  VMD development is 
supported by the NIH National Center for Research Resources.

A full description of VMD is available via the VMD WWW home page:
        http://www.ks.uiuc.edu/Research/vmd/

The authors request that any published work which utilizes VMD includes 
a reference to the VMD web page and/or the following reference:

  Humphrey, W., Dalke, A. and Schulten, K., "VMD - Visual Molecular
  Dynamics", J. Molec. Graphics, 1996, vol. 14, pp. 33-38.

The Theoretical Biophysics group encourages VMD users to be closely  
involved in the development process through reporting bugs, contributing  
fixes, periodical surveys and via other means.

We are eager to hear from you, and thank you for using our software!

                                                John Stone
                                                vmd@ks.uiuc.edu
                                                January 7, 2000


-- 

Theoretical Biophysics Group   Email: johns at ks.uiuc.edu
Beckman Institute              http://www.ks.uiuc.edu/~johns/
University of Illinois         Phone:  (217) 244-3349
405 N. Mathews  Ave              FAX:  (217) 244-6078 
Urbana, IL 61801, USA          Unix Is Good For You!!!



From owner-bio-software@hgmp.mrc.ac.uk  Mon Jan 10 09:27:19 2000
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From owner-bio-software@hgmp.mrc.ac.uk  Mon Jan 10 13:24:15 2000
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To be able to compare some DNA assembly programs, I'm looking for raw
DNA sequences (abi format) from a shotgun cloning and the final assebled
sequence (BAC,..). It seems that it isn't possible to download this kind
of files from the web. Can somebody help us?

thanks
-- 
==============================================================================
Stefan Weckx				
University of Antwerp				
Belgium
==============================================================================


From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan 11 07:10:46 2000
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From: spam@127.0.0.1 (Bernard Murray, PhD)
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Date: Mon, 10 Jan 2000 22:09:42 -0700
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In article <3879DEA5.1BC3B03E@uia.ua.ac.be>, Stefan Weckx
<sweckx@uia.ua.ac.be> wrote:

> To be able to compare some DNA assembly programs, I'm looking for raw
> DNA sequences (abi format) from a shotgun cloning and the final assebled
> sequence (BAC,..). It seems that it isn't possible to download this kind
> of files from the web. Can somebody help us?

To get some ideas on creating a fake dataset you might want to
look at an earlier study;

Miller MJ & Powell JI (1994)
"A quantitative comparison of DNA sequence assembly programs."
J Comput Biol 1994 Winter;1(4):257-69 

They looked at a real dataset and used this to
design fake sets with different error levels.

   Bernard

-- 
Bernard P. Murray, PhD
bpmurray at cgl . ucsf . edu
Department of Cellular & Molecular Pharmacology, UCSF


From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan 11 07:33:33 2000
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From: Ken Beath <kjbeath@kagi.com>
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Subject: [Ann] GLMStat (Macintosh) generalized linear models software
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GLMStat is a Macintosh-based (NOTE: currently no Windows or UNIX
version) statistical program for analysing generalised linear
models. Features of GLMStat are

 - spreadsheet style data entry
 - factors may be represented as either integers or strings (categories)
 - Normal, Poisson, Binomial and Gamma models with appropriate links
and  specification of convergence and aliasing parameters
 - Scatter and Residual plots
 - Matrix scatterplots
 - Box and Whisker plots
 - Frequency distribution histograms
 - Descriptive statistics.
 - Output of deviance, parameter estimates, residuals and parameter
correlations
 - Saving of data files complete with all model specifications.
 - printing of data, graph and results.
 - Missing values
 - Online Help (under the apple menu) and a brief User Manual.
 - includes example data files for most examples in two of the texts.
 - Individual licences available for $US25. 10 User Site Licences
$US100. Site licences $US200. World site licence $US500. Payment in $US
through Kagi Shareware.
 - Registration includes free upgrades to version 6.x

Unregistered copies are fully functional except that Save and Save As
are disabled and there are
some limitations on usage.
 
GLMStat is available for download at info-mac archives or from
   http://www.ozemail.com.au/~kjbeath/glmstat.html
   
   
Ken Beath
kjbeath@kagi.com


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cancel <110120001829443898%kjbeath@kagi.com>


From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan 11 13:00:18 2000
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From: "Ivan Petrovic" <easyzip@softwarecenter.net>
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Subject: PowerArchiver 2000 v5.01 - !!! OLD NAME EASYZIP !!!
Date: Tue, 11 Jan 2000 13:58:24 +0100
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* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
PowerArchiver 2000 v5.01 [11th January 2000]
(old name EasyZip)
The most powerful Freeware Archive Utility that exists...
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

What is PowerArchiver?

PowerArchiver is the most powerful and totally FREE Archive
Utility... List of some features:
     * full built-in support for ZIP, CAB, LHA(LZH), TAR,
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       ARC, ACE, ZOO and GZip archives
    * full built-in support for XXE and UUE Internet encoded files
    * multiple disk spanning, powerful SFX archives, passwords,
       comments, renaming files within archive, installing archive,
       checking archive for viruses
     * integrated viewer with support for TXT, RTF, BMP,
        JPG(JPEG), ICO, WMF and EMF files, ...
     * complete integration with Windows Explorer: d&d, powerful
        Explorer Shell Extensions, ...
     * tool for converting between archive formats  (CAB ->
        LHA, ...), tool for splitting single ZIP archive, tool for
        detecting  archive type, ...
     * great interface similar to other popular archive utilities with two
        modes of viewing archive (Classic &  Explorer style), integrated
        file browser, ...
     * detailed help in new MS HTML Help format with the tutorial for
       beginners, ...
    * and many, many more useful and powerful features...

So try out this great utility.

What's new?

    Changes in this version --> EasyZip renamed  to  PowerArchiver,
added  support for writing TAR and TAR.GZ archives, internal viewer
now  beside TXT files supports RTF, BMP, ICO, WMF, EMF and
JPG (JPEG) files, tool for detecting archive format, selecting custom
toolbar buttons now available using "Small buttons", small misc
features  and many, many bug fixes...
    For detailed list of new features and bug  fixes  please  visit
PowerArchiver Forum at http://ipsoft.cjb.net

Support:

    PowerArchiver and more and more information about PowerArchiver
 you can find at:

            http://ipsoft.cjb.net

    and my e-mail address is:

            powerarc@ipsoft.cjb.net

Thanks in advance...
Ivan Petrovic



--
___________________________________________________________
  PowerArchiver 2000 - The most powerful and Free Archive
  Utility  for  Windows  95/98/NT/2000  that has built-in
  support for many, many formats: ZIP, CAB, LHA, BH, ARJ,
  RAR, ACE, ARC, ZOO, TAR, GZ, XXE, UUE...
-----------------------------------------------------------
  ArchiveUtilities - 2  Free console programs with source
  in Borland Delphi
    ArcComp - compresses to ZIP, CAB,  LHA  and BH
    ArcExt  - extracts from ZIP, RAR, ARJ, CAB, LHA, ARC,
              ACE, GZIP, TAR, UUE and ZOO
  * * * * * * * * * * * * * * * * * * * * * * * * * * * *
                  http://ipsoft.cjb.net
                ivanpetrov@ipsoft.cjb.net
  * * * * * * * * * * * * * * * * * * * * * * * * * * * *





From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan 11 14:20:28 2000
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From: "Soeren W. Rasmussen" <swr@crc.dk>
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Subject: SAGE analysis with DNATools
Date: Tue, 11 Jan 2000 15:13:53 +0100
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Dear DNATools user,

In case you use the SAGE functions (extract tags, tag file tools and
analysis functions) it might interest you to know that it is now
possible to im- and export sage tag files in the same format as is used
by NCBI (http://www.ncbi.nlm.nih.gov/SAGE/). The latest release of
DNATools, 5.1.653, also allows you to load SAGEmap files for identifying
your tags - and contains a function which let you create a SAGE map file
from your own annotated sequences. Most of the SAGE routines have been
optimised and now run a bit faster. Remember, however, that you still
need other, more sophisticated/powerful programs for analysis of very
large data set. We routinely use the programs for tag files of about
20,000 tags.

Please remember that comments and ideas are always welcome.

Regards


Soeren

--
Dr. scient. Søren W. Rasmussen
Carlsberg Laboratory, Department of Physiology
10 Gl. Carlsbergvej, DK-2500, Copenhagen, Denmark
Phone  45 33275230/45 36162259, Fax 45 33274766
swr@crc.dk, http://www.crc.dk/phys/

DNATools sequencing software:
http://www.crc.dk/phys/dnatools.htm




From owner-bio-software@hgmp.mrc.ac.uk  Tue Jan 11 22:10:10 2000
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From: "Stephen R. Lasky" <srlasky@cellworks.mbt.washington.edu>
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Subject: Re: phrap quality scores
Date: Tue, 11 Jan 2000 21:50:18 +0000
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"Rachel M. Kadel-Garcia" wrote:
> 
> In article <387698C5.EEA17FB@cellworks.mbt.washington.edu>,
> Stephen R. Lasky wrote:
> >"Rachel M. Kadel-Garcia" wrote:
> >>
> >> Does anyone here have an understanding of phrap quality scores
> >> beyond what's in the docs?  I'm trying to figure out how to
> >> assign similar quality scores to assemblies not done with phrap,
> >> and I'm resorting to spelunking in the source, but it's rough
> >> going.
> >>
> >>                                                 Rachel
> >
> >
> >Phrap, I believe, is not the program assigning the quality scores.
> >Phred is.  Phrap uses the phred quality scores to do its alignments.
> 
> Phred assigns quality scores to bases in individual reads.  Phrap uses
> those quality scores and various things about the alignments to generate
> consensus quality scores.
> 
>

Sorry, you are correct.  Phrap does assign a quality score for the
concensus sequence based on the quality of the raw data (phred q score)
and the extent of confirmation of the base by other reads.

I do not know how to deconvolute that score.

srl

-- 
Stephen R. Lasky, Ph.D.			#
University of Washington		#
Department of Molecular Biotechnology	#
HSB K336a box 357730			#
Seattle, WA, 98195 USA			#
email:	srlasky@u.washington.edu	#
Phone: 	206-616-5865			#
Fax:	206-685-7301			#
#########################################


From owner-bio-software@hgmp.mrc.ac.uk  Wed Jan 12 13:57:53 2000
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From: Patricia Rodriguez-Tome <tome@sol6.ebi.ac.uk>
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Subject: CORBA workshops at the EBI
Date: 12 Jan 2000 13:57:47 +0000
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The EBI will run 2 series of CORBA workshops

CORBA programming : 25-28 january 2000 and 13-15 March 2000

Advanced CORBA programming : 24-26 May 2000 and 4-6 July 2000

More information about the agenda and costs (sorry we do not have yet any 
funding for these workshops ) is available at:
http://corba.ebi.ac.uk/courses

Only the first 2 workshops pages are up. January is open only to
European participants , March is open to all.
In February, after the first workshop, the second series of pages will 
come up.


Please pass this information around for those you think might be interested. 
March and May workshops might be cancelled if there are not enough attendees,
 so it would be good to give us  a feedback if anyone plans to attend.

Cheers

Pat
-- 
=======================================================================
Dr. Patricia Rodriguez-Tome		| URL:  http://www.ebi.ac.uk
R & D Coordinator - Team Leader
The EMBL Outstation, Hinxton - The European Bioinformatics Institute
Wellcome Trust Genome Campus, Hinxton	| Tel:	+44 (0)1223 494 409
Cambridge CB10 1SD, UK			| Fax:	+44 (0)1223 494 468
========================================================================


From owner-bio-software@hgmp.mrc.ac.uk  Wed Jan 12 18:05:07 2000
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From: j3@post.com (J3)
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Subject: Re: Looking for Cloning Software
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I strongly suggest pDRAW32 because its free (well, really beerware).
If you can afford to spend some money then go with Redasoft's Plasmid
v1.1.

Just my $0.02 worth as a grad student of molecular biology.

- J3 -


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From owner-bio-software@hgmp.mrc.ac.uk  Thu Jan 13 17:02:29 2000
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From: hh645@hotmail.com
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Subject: Need More Money? Need Health Benefits?
Date: 13 Jan 2000 17:02:24 -0000
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From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan 14 00:11:38 2000
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Send an email with "THE LIST" in the subject line to

auto.program.list@iname.com If not working send To uik87g@writemail.com

"SoftWare For P.C And Apple Macintosh"

...And we will send you a Full List with just about any Software package
that's going.
"strictly for backup purposes only" and is identical to the original master
copy.






From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan 14 03:02:08 2000
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From: expomed@mindspring.com (MARTY THOMAS)
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Subject: Human Anatomy Program Updated
Date: 14 Jan 2000 03:01:36 GMT
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Gold Standard Multimedia Human Anatomy

Human Anatomy is an interactive, HTML based, cadaveric dissection 
tutorial. Designed to be used as a comprehensive supplement to the 
gross lab, this program takes the student step-by-step through 
dissection procedures using the world's largest collection of 
cadaveric photographs, hundreds of hand-drawn illustrations, 
and photos from models and skeletons.

In the practice mode, students can quiz themselves 
with the 4,700 multiple choice test questions and receive 
immediate feedback. Human Anatomy's point-and-click
interface supports all learning syles and teaching efficiency.

*14,000 references to over 6,000 cadaveric photographs.
*3D icons illustrating the orientation and field of 
view of the photos.
*Chapter and page references to frequently-used anatomy atlases: 
Netter's Grant's and Rohen/Yokochi.
*Over 4,700 quiz questions featuring immediate feedback and 
links back to the tutorial for review.
*Image enlargement to full screen size.
*Hundreds of hand-drawn illustrations with links to cadaveric photographs.
*Find feature locates any structure easily.
*Browser included.

http://www.expomed.com/humanat.htm 
http://www.visualman.com/gsm/humanat.htm
-- 
/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/
Martin Thomas, expomed@mindspring.com
http://www.onsitedrugtesting.com/ Onsite Drug Testing
http://www.expomed.com/ Personal Protection Products
http://www.visualman.com/ Educational Software



From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan 14 03:41:50 2000
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From: "Mike Jones" <Mjones@jonestown.org>
Subject: Charting / Data Graphics For Windows
Date: Thu, 13 Jan 2000 21:36:31 -0600
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www.clickitgraph.com

Rated 5 Stars by ZDNET -
http://hotfiles.zdnet.com/cgi-bin/texis/swlib/hotfiles/info.html?fcode=0012P
E&b=

ClickIt Graph is state of the art 32 bit data graphics software for Windows®
95, 98 and NT 4.0. ClickIt Graph is a user friendly full featured data
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compatible with Microsoft Access® that allows for the ease of use, data
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supports linking with Microsoft Word® and PowerPoint® 97 and 2000. Transfer
of ClickIt Graph drawn graphs to a Word® document or PowerPoint®
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equations for line, scatter, linear-logarithmic, logarithmic-logarithmic,
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functions are output to the graph legend and a text file. Error bars are
available for most graph types.






From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan 14 14:01:37 2000
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http://www.es.embnet.org/~biocomp/bioinfo2000/


From owner-bio-software@hgmp.mrc.ac.uk  Fri Jan 14 16:40:06 2000
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From: Ira Haron <iraharon@erols.com>
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Subject: help find this book
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Group,

Can anyone help me find this book/manual/pamphlet?

***************************************************

  Name:
  Image Processing Tutor (IPT).


  Info on publisher:
  Copyright Unitron Services
  Flat 104
  Brigade Links, 54/1
  Sesharipuram
  1st Main Road
  Bangalore - 560 020
  Phones 36 35 32 336 10 58


  Physical description:
  Spiral bound, Approximately 120 pages
  Ver 1.1, Release Date November 1, 1994


  Quoted from first page:
"Getting Started:
Image Processing Tutor is a work book cum software combination to
introduce the concepts Digital Image Processing through experiments done

with a PC equipped with an M8 frame grabber board ..."

**************************************************

thank you for your time and courtesy,

ira
iraharon@erols.com








From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan 15 08:49:18 2000
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From: main@mainengineering.com (Lou Main)
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--947897588762B0018==
Content-Type: text/plain
Content-Transfer-Encoding: quoted-printable

If you own a nice auto or plan on buying one this year and want
to keep it, you need to read the following information, if not
please delete.

Main Engineering Corporation, a unique vehicle security
manufacturer with several patented systems to it's credit
advocating "total immobility", is presently launching their
newest product.

The HotSeat is the newest, most protective, completely automatic
anti-car jacking and security system to ever hit the market.  A
unique system providing maximum safety to the driver/owner and
promotes a "No High Speed Pursuit" scenario.  This alone saves
your customers and their insurance companies thousands of
dollars from property damage and bodily injury lawsuits.  Easy
to install, undetectable by the thief, impossible to shutdown
after the automatic timing sequence has started and convenience
for the customer.

Some Features of the HotSeat are:
*  Completely automatic, no driver intervention
*  Impossible to become part of any "High Speed Pursuit"
*  Provides a safety net for the victim
*  Vehicle - easy recovery - within sight
*  Inexpensive to own
*  Insurance savings
*  Also used as a security system
*  Provides a "No Start" alarm-siren with theft attempts
*  Undetectable by the thief
*  No false alarms to contend with
*  Cannot accidently activate system
*  Easy to install

Main Engineering is presently seeking individuals
that want to keep what they own.  We are setting up installation
facilities around the US and abroad that want to get in on the
ground floor of this new and exciting product.

If you would like more detailed information please go to our
website at http://www.mainengineering.com/index_1.htm or respond
by email to main@mainengineering.com.  You can also phone us
toll free at 877-748-5340.

We build only the finest security systems available anywhere,
we do not make alarms.

Thank you for the time you have given this information and we
hope to hear from you soon.

Best regards,
Lou Main, CEO
Main Engineering Corporation

--947897588762B0018==--
---


From owner-bio-software@hgmp.mrc.ac.uk  Sat Jan 15 18:35:07 2000
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From: "S.W. Rasmussen" <swr@crc.dk>
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Subject: Re: SAGE analysis with DNATools
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Dear DNATools user,

I may have been a bit too quick publishing the updated SAGE functions.
Unfortunately, there is a number of bugs in 5.1.653 (in the SAGE functions, the
remaining functions were not changed in 563). I have corrected them all (I hope)
in revision 654 which will be available for downloading monday, 17.1. Sorry.

Regards

Soeren

-- 
Soeren W. Rasmussen, Dr. scient.
Department of Physiology
Carlsberg Laboratory
Copenhagen, Denmark
swr@crc.dk, http://www.crc.dk/phys


From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan 16 01:36:14 2000
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From: greg@franklin.burnham-inst.org (Dr. Greg Quinn)
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Subject: Functional equivalent of GCG Findpatterns?
Date: 16 Jan 2000 01:39:43 GMT
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Hi;
Does anyone know of a publicly available functional equivalent of the GCG 
FindPatterns program?
Thanks
Greg


From owner-bio-software@hgmp.mrc.ac.uk  Sun Jan 16 13:33:18 2000
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Subject: Re: Functional equivalent of GCG Findpatterns?
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>>>>> "Greg" == Greg Quinn <greg@franklin.burnham-inst.org> writes:

    Greg> Hi; Does anyone know of a publicly available functional
    Greg> equivalent of the GCG FindPatterns program?

The EMBOSS program fuzznuc will search sequences or databases for
arbitrary, short patterns in a similar manner to findpatterns. It
allows a number of mismatches to be supplied.

The output is more terse than findpatterns, but on the other hand
there are no arbitrary limits on the length of sequence to be searched
or number of hits reported.

fuzznuc is part of the EMBOSS package which already covers much of
GCG's functionality. It's homepage is at:

http://www.sanger.ac.uk/Software/EMBOSS/

hth

-- 

Keith James  --  kdj@sanger.ac.uk  --  http://www.sanger.ac.uk/Users/kdj
The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA


From owner-bio-software@hgmp.mrc.ac.uk  Mon Jan 17 11:48:21 2000
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Subject: Re: Functional equivalent of GCG Findpatterns?
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Keith James <kdj@fes1.sanger.ac.uk> writes:

> >>>>> "Greg" == Greg Quinn <greg@franklin.burnham-inst.org> writes:
> 
>     Greg> Hi; Does anyone know of a publicly available functional
>     Greg> equivalent of the GCG FindPatterns program?
> 
> The EMBOSS program fuzznuc will search sequences or databases for
> arbitrary, short patterns in a similar manner to findpatterns. It
> allows a number of mismatches to be supplied.
> 
> The output is more terse than findpatterns, but on the other hand
> there are no arbitrary limits on the length of sequence to be searched
> or number of hits reported.

It would be relatively easy to extend the output of fuzznuc
if users have particular needs.

One option under active consideration, for example, is to report the
hits in feature format (currently GFF, but soon also EMBL/Genbank
feature format and SwissProt for fuzzpro)

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/


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From: "SteoBio" <stia_g@yahoo.com>
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Subject: Multi analyst
Date: Mon, 17 Jan 2000 17:06:16 +0100
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Recently, i have downloaded this program from the Bio-Rad ftp server, but it
doesn't run because needs hardware key. Who knows the program? is there a
way to make it run (crack)?
Thanks

Stefano




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From: greg@franklin.burnham-inst.org (Dr. Greg Quinn)
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Subject: Re: Functional equivalent of GCG Findpatterns?
Date: 17 Jan 2000 19:16:23 GMT
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References: <85r7gv$hso$1@franklin.ljcrf.edu> <sc4ogamrvj9.fsf@fes1.sanger.ac.uk> <sub3drw537m.fsf@europa.sanger.ac.uk>
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I appreciate the direction of the EMBOSS project,but I'm not sure that 
FuzzNuc, or I guess the one that I would be interested in, FuzzPro is 
the functional equivalent of FindPatterns; unless I missed something 
on the description page for FuzzPro, I didn't see a specific query
sequence syntax of the kind found in FindPatterns that precisely allows
me to specify particular residues at each position in the query. It's
this kind of ability which I'm looking for....

Peter Rice (pmr@sanger.ac.uk) wrote:
: Keith James <kdj@fes1.sanger.ac.uk> writes:
: 
: > >>>>> "Greg" == Greg Quinn <greg@franklin.burnham-inst.org> writes:
: > 
: >     Greg> Hi; Does anyone know of a publicly available functional
: >     Greg> equivalent of the GCG FindPatterns program?
: > 
: > The EMBOSS program fuzznuc will search sequences or databases for
: > arb