From owner-srs@net.bio.net Thu May 04 23:00:00 1995
Path: biosci!agate!howland.reston.ans.net!vixen.cso.uiuc.edu!usenet.ucs.indiana.edu!sunflower.bio.indiana.edu!gilbertd
From: gilbertd@sunflower.bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software.srs
Subject: Mac port is available
Date: 5 May 1995 04:12:41 GMT
Organization: Biology, Indiana University - Bloomington
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I've modified Thure Etzold's SRS, version 4.02, to work on macintoshes.
It is available at IUBio Archive, 
   ftp://iubio.bio.indiana.edu/molbio/browse/srs-on-mac/

Included here is every thing you need to use it w/o compiling it, in
68K and PPC versions, some sample data, as well as the modified source 
files and files of differences from the original, and project
files for compiling it with CodeWarrior.

Note: SRSwgetz doesn't interface w/ Mac HTTPD servers because I haven't
rewritten the Unix "getenv()" format to use Apple Events for 
inter-application communications.

-- Don
-- 
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-srs@net.bio.net Sun May 07 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!Germany.EU.net!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold>
Newsgroups: bionet.software.srs
Subject: Re: Mac port is available
Date: 8 May 1995 12:55:22 GMT
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gilbertd@sunflower.bio.indiana.edu (Don Gilbert) wrote:
>I've modified Thure Etzold's SRS, version 4.02, to work on macintoshes.
>It is available at IUBio Archive, 
>   ftp://iubio.bio.indiana.edu/molbio/browse/srs-on-mac/
>

I will try to incorporate these changes as soon as possible - they 
will probably be in the release 4.06 ...so the overnext release 

>Note: SRSwgetz doesn't interface w/ Mac HTTPD servers because I haven't
>rewritten the Unix "getenv()" format to use Apple Events for
>inter-application communications.

that function as soon as it becomes available should be easy to incorporate
..there is a function 
void FilSetTranslate (char *(*translate)(char *, INT4)); (futil.c)x
that sets a new function for translating environment variables to real path names

regards
Thure

===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany


From owner-srs@net.bio.net Tue May 23 23:00:00 1995
Newsgroups: bionet.software.srs
Path: biosci!agate!howland.reston.ans.net!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: ListA4
Message-ID: <1995May24.115033.18943@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
Distribution: bionet
Date: Wed, 24 May 1995 11:50:33 GMT
Lines: 168

The SDL files for LISTA are available  at the sources mentioned below.
Regards
Reinhard 





[ Article crossposted from bionet.molbio.yeast ]
[ Author was patrick linder ]
[ Posted on 24 May 1995 10:09:23 +0100 ]



Dear Netters,


We are happy to announce the release of ListA4.1. The document which 
follows has been extracted (and shortened) from lista.doc describing 
the database. Please refer to the original document for full documentation.


For comments, informations and suggestions, please contact:
Patrick Linder, Dept. of med. Biochemistry, CMU, 1, rue Michel Servet, 
1211 Geneva, Switzerland

Tel +41 22 - 702 54 84
FAX +41 22 - 702 55 02
Email: linder@cmu.unige.ch




=======================================================================
LISTA, Release 4.1, March 1995

A comprehensive compilation of nucleotide sequences encoding proteins 
from the yeast Saccharomyces


      Doelz, R., Mosse, M. O., Slonimski, P. P., Bairoch, A.
      and Linder, P. (1994). LISTA, LISTA-HOP and LISTA-HON: a 
      comprehensive compilation of protein encoding sequences 
      and its associated homology databases from the yeast 
      Saccharomyces. Nucleic Acids Res. 22, 3459-3461.



3.2.1 NEW DATA FIELDS IN RELEASE 4

The CL field (chromosomal localization) was added in order to indicate
where the gene has been localized. The AC field (accession number) was
added, one for each entry. Note that the accession numbers start with SC
(for Saccharomyces Cerevisiae). Access ion numbers introduced in the
interim release 3.1 were dropped, to account for the principle of one
accession number per gene rather than one per quoted reading frame. The DT
field has been added to facilitate maintenance. . 

3.2.2 CROSS-REFERENCESTO THE SWISS-PROT DATABASE 
Since release 4.1 an effort has been made to
include all the entries in SWISS-PROT and to introduce a DR field for
crossreference with Swissprot. This supplements the functionality as
already present earlier as via the SWSS-PROT database is immediately 
linked to the corresponding MEDLINE reference quotation via the SRS system
(see below). 



3.4 GROWTH 

LISTA 4.1 contains data from 1909 sequences,corresponding to 1420 genes
and 376 synonyms. The exact growth curve is shown below: 

LISTA 1      400 genes and synonyms
LISTA 2      811 genes, 125 synonyms, 1001 sequences
LISTA 3     1127 genes, 176 synonyms, 1400 sequences
LISTA 4.1   1420 genes, 376 synonyms, 1909 sequences 


4 NOMENCLATURE

Genetic nomenclature relies on the glossary compiled by [6] and was used
whereever possible. In many cases, however,no or incorrect gene
designations have been given to published sequences.Moreover,the same name
was given to different sequences or differen t names have been given to
the same sequence. To sort out this problem of nomenclature a priority
rule for naming genes in the present database [2] was established.
According to this rule the name of the first pub- lished sequence (date of
acceptance of th e publication) is used in the list, provided it is in
accordance with the standard genetic nomenclature.Other names are included
as synonyms. In some cases four letter designations (ARGR1,MRPL20) or gene
names followed by a letter (RPL4A, TIF51A) have als o been used. In the
case of historically well established gene designations such as HO,it was
self- evident that they should be retained. 

Although these rules are straight and easy to handle, in some cases this
leads to the use of names which are no longer in use. In such cases the
currently used name is given and the "historical" name is given as
synonym. 


6 STATUS OF THE DATABASE

6.1. AVAILABILITY 

The LISTA database is available either by anonymous FTP from
bioftp.unibas.ch [131.152.8.1] in the archive_data/lista directory or its
mirror ftp.switch.ch [130.59.1.40] in the
mirror/embnet-ch/archive_data/lista directory on the internet. New
sequences a nd comments on the existing database may be sent to P. Linder
(linder@cmu.unige.ch). LISTA is distributed by the EMBL data library and
the associated services (CD-ROM, FTP, EMAIL servers). 

ListA can also be queried using the SRSWWW system on one of the
corresponding servers, e.g. http://www.ch.embnet.org/srs/srsc. 


6.2. FUTURE (INCREMENTAL) RELEASES

Further releases are still open for feed-back and suggestions, and it is
suggested to contact linder@cmu.unige.ch for comments and desired
enhancements.

An effort will be made to add new entries to the existing list
without any announcement. The new entries will be available in Lista4_new.


6.3. ADDITIONS: HOMOLOGY CALCULATIONS

The LISTA database does not currently contain any sequence data from
entries available in the EMBL data library. Experimental versions of an
EMBL-formatted file which includes sequence data are available as
LISTA-HON (the homologies on the Nucleotide leve l) and LISTA-HOP (the
homologies on the Protein level). The release of ODD files describing the
LISTA , LISTA-HON and LISTA-HOP format for parsing into the SRS system [7]
is experimental at this point of time and suggestions are most welcome to
doelz@ch.e mbnet.org (Reinhard Doelz, address see above). 


6.4. FILES FOR USE IN THE SRS SYSTEM

The SDL files to be modified are srsdb.sdl, hyperlink.sdl and lista.sdl. 
The latter is provided as part of the distribution. For proper
integration, do the following additions similar to the example: 
(lines without : are wrapped for ease of reading) 



7 ACKNOWLEDGEMENTS

We are very grateful to all those, who have provided input in solving
nomenclature problems and giving informations on inconsistencies. We would
also like to thank Thure Etzold for assistance in building the LISTA.SDL
file.This work was supported by grants from the Ministere de la Recherche
et de l'Espace (program GREG; P.S.), from the Swiss National Science
Foundation (R.D. and A.B), the University of Basel (R.D. and P.L) and the
University of Geneva (P.L.  and A.B.). We are very grateful to S.
Brouillet, J.L. Risler and the Rechenzentrum of the University of Basel
for help. 




-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-srs@net.bio.net Tue May 23 23:00:00 1995
Newsgroups: bionet.software.srs
Path: biosci!bcm!cs.utexas.edu!news.sprintlink.net!gatech!EU.net!ieunet!maths.tcd.ie!news.tcd.ie!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Method to do indexing @production server
Message-ID: <1995May24.170405.29434@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
Date: Wed, 24 May 1995 17:04:05 GMT
Lines: 102


Colleagues, 
we need to index data while the server is expected to answer replies. As 
the normal procedure of srscheck/srsupdate will invalidate indices during
the process of srsbuild, we came up with the following solution. Maybe you 
have found a better way of doing it, we'd like to hear from you! 

Note: 
The following still assumes that the data are not needed, only the indices. 
This is OK as long as searches or SRS operations need only the indices.
This assumption is only true as a rough approximation. Procedures could be 
developed which handle this, too. 

Principle: 

1. Buy disks. 
2. Make a scratch dir and symlink each entry in SRSINX. 
3. Parse output from srscheck and delete all symlinks to files which are  
   to be rebuilt. 
4. reassign SRSINX and rebuild indices. 
5. Delete all symlinks in the scratch directory. 
6. copy all newly created indices into production SRSINX. 

The following shell does this, exemplarically. 
In order to map logical names to file names, the following awk script is 
needed (must be modified, too).

============================> map.awk <=====================================
{
  if ($1 == "XEMBL")     {  print "xembl"      } 
  if ($1 == "XXEMBL")    {  print "xxembl"     }
  if ($1 == "EMNEW")     {  print "emnew"      }
  if ($1 == "GBNEW")     {  print "gbnew"      }
  if ($1 == "GBNEW_EXCL"){  print "gbnew_excl" }
  if ($1 == "TREMBLNEW") {  print "tremblnew"  }
} 
=============================> end of map.awk <==============================

=========================> update.csh <===================================
#!/bin/csh 
unlimit                                              # common SRS practice
setenv SCRATCHBIN /bioz1/software/www/SRSUPDATE      # location of map.awk
setenv SCRATCHINX /biox4/srs                         # scratch directory

source /bioz1/software/www/SRS/etc/prep_srs          # srs prep

#
#----------------------------------- create linkages 
#
        cd $SRSINX
        foreach i (*)
                ln -s $SRSINX/$i $SCRATCHINX/$i
                end
        cd $SCRATCHINX
#
#------------------------------------ see, is there something to be done? 
        srscheck >& log 
        cat log | grep must | nawk '{n = split ($0,field,"\""); print field[2]}' | nawk -f $SCRATCHBIN/map.awk | sort -u  > log2
#
#----------------------------------- delete all links which have these 
#
        unalias ls
        foreach i ( `cat log2`) 
                rm $SCRATCHINX/$i''*
                end
#
#---------------------------------- establish working index 
#
        setenv SRSSAV $SRSINX
        setenv SRSINX $SCRATCHINX
#
#---------------------------------- redo the srscheck and do srsupdate
#                                   (dont reassign SRSINX in prep_srs)
        srscheck 
        cat `which srsupdate`  | grep -v prep_srs > $SCRATCHBIN/pilot.csh
        source $SCRATCHBIN/pilot.csh
#
#---------------------------------- remove all files which are symlinks 
#
        cd $SCRATCHINX
        find . -type l -exec rm '{}' 
#
#---------------------------------- copy newly survived index files 
#
        foreach i (*)
                cp $i $SRSSAV
                end


=========================> end of update.csh <===============================

I forgot to mention that this works only on UNIX. 

Regards
Reinhard


-- 
 R.Doelz         Klingelbergstr.70| Tel. x41 61 267 2247  Fax x41 61 267 2078|
 Biocomputing        CH 4056 Basel| electronic Mail    doelz@ubaclu.unibas.ch|
 Biozentrum der Universitaet Basel|-------------- Switzerland ---------------|
<a href=http://beta.embnet.unibas.ch/>EMBnet Switzerland:info@ch.embnet.org</a> 

From owner-srs@net.bio.net Thu May 25 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!vixen.cso.uiuc.edu!prairienet.org!sword
From: sword@prairienet.org (Andrew D. Seale)
Newsgroups: bionet.software.srs
Subject: 486 motherboard
Date: 26 May 1995 23:08:26 GMT
Organization: Prairienet, the East-Central Illinois Free-Net
Lines: 9
Message-ID: <3q5n1a$bp1@vixen.cso.uiuc.edu>
NNTP-Posting-Host: firefly.prairienet.org
X-Newsreader: TIN [version 1.2 PL2]

Looking for a 486 mother board.  Right now just wanna see whats out on 
the market.  

--
=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=
|        Andy Seale          |          Go to my homepage!!!              |
|    sword@prairienet.org    |     http://www.prairienet.org/~sword/      |
=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=*=


From owner-srs@net.bio.net Mon May 29 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!Germany.EU.net!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold>
Newsgroups: bionet.software.srs
Subject: srs4.05 is ready
Date: 30 May 1995 14:43:32 GMT
Organization: EMBL Heidelberg
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X-URL: news:bionet.software.srs

dear all,

release 4.05 of SRS is available now. Get the file
pub/software/unix/srs/srs4_05.tar.gz via anonymous ftp from
felix.embl-heidelberg.de


There were some problems installing SRS with the new httpd from NCSA as
reported by Jack Leunissen and Steve Taylor which should be fixed now. The
cgi's and the document files are declared to reside now in two different 
directories (see the installation procedure in the README of the distribution or
http://www/srs/srsman_install.html. Please tell me if it works or if there are
still problems with it.

I added Tom Boutell's 'gd' library for creating GIF images and a new program
'srspict' that creates a picture with the databank network and a link diagram.
for the network it needs a file with the coordinates of all databanks which you
can create with a tcl/tk script (primitive graph editor) ...instructions in README.

The last important change is the complete replacement of the algorithm for finding
the shortest path in the library network ...which was about to crack on large
systems. The new algorithm is much faster and should work even with several hundred
databanks;-).

Here is the complete list of changes since srs4.04:

1995/04/05
   if a flat file is not accessible, eg, the file est.dat from
   embl then this will be mentioned only once ...eg during
   listing a list of embl entries together with selected
   fields ...still the names for these entries can be
   displayed 

1995/05/05
   Added function LibIsDataType which tells whether a
   databank contains "protein" or "dna" sequences
   ...function can be easily extended for other data types 

1995/05/05
   GCG formatted list file for features does not list
   "Strand" for protein sequences 

1995/05/05
   enhanced srscheck to look at all single indices if they
   need rebuilding or compression 

1995/05/05
   fixed problem with retrieving integer ranges ...integers
   are no longer treated as floats 

1995/05/05
   prep_srs puts the srs directories at the begin of the
   PATH variable 

1995/05/05
   the '?' for begin and end positions in swissprot are now
   understood 

1995/05/09
   a number of blast files can now be indexed - each entry
   witll receive a name composed of filename, number
   within that file, and the sequence found (eg, swissprot
   name). The file names are stored in the IDX file 

1995/05/09
   added new attribute isSystem for #field - all fields
   marked with that should be ignored by user interfaces -
   use LibIsField (field, "system") to find out. 

1995/05/10
   Replaced the algorithm for finding the shortest path in
   the library network ...now there is NO limit left to
   hinder its growth 

1995/05/17
   Added buffer function for matching regular
   expressions 

1995/05/17
   Changed script module so that it understands variables
   in labels and in the text 

1995/05/19
   the script module provides now a utility to check
   number and type of arguments when printing from a
   label with print arguments 

1995/05/26
   executables and document files can now be in different
   directories 

1995/05/26
   stdout for SRSWWW is no longer buffered. This fixes
   a problem with the httpd on OSF1 



..have fun
regards
thure



-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany


From owner-srs@net.bio.net Tue May 30 23:00:00 1995
Path: biosci!daresbury!hgmp.mrc.ac.uk!news.hgmp.mrc.ac.uk!pmr
From: pmr@sanger.ac.uk (Peter Rice)
Newsgroups: bionet.software.srs
Subject: Re: srs4.05 is ready
Date: 31 May 1995 15:37:01 GMT
Organization: MRC Human Genome Resource Centre
Lines: 23
Distribution: world
Message-ID: <PMR.95May31163702@unst.sanger.ac.uk>
References: <3qfauk$6h7@comet.EMBL-Heidelberg.DE>
NNTP-Posting-Host: unst.sanger.ac.uk
In-reply-to: Thure Etzold's message of 30 May 1995 14:43:32 GMT
CC: pmr

In article <3qfauk$6h7@comet.EMBL-Heidelberg.DE> Thure Etzold <etzold> writes:
>release 4.05 of SRS is available now. Get the file
>pub/software/unix/srs/srs4_05.tar.gz via anonymous ftp from
>felix.embl-heidelberg.de
>
>I added Tom Boutell's 'gd' library for creating GIF images and a new program
>'srspict' that creates a picture with the databank network and a link diagram.
>for the network it needs a file with the coordinates of all databanks which you
>can create with a tcl/tk script (primitive graph editor) ...instructions in README.

I now have the new database GIFS (tcl/tk script and srspict program) working
and running with the CERN web server (the image map format is different).

If anyone is interested, I can provide more details of the changes. I have
passed them on to Thure for inclusion in a future release.

--
------------------------------------------------------------------------
Peter Rice                           | Informatics Division
E-mail: pmr@sanger.ac.uk             | The Sanger Centre
Tel: (44) 1223 494967                | Hinxton Hall, Hinxton,
Fax: (44) 1223 494919                | Cambs, CB10 1RQ
URL: http://www.sanger.ac.uk/~pmr/   | England

