From owner-srs@net.bio.net Tue Oct 01 23:00:00 1996
Path: biosci!agate!howland.erols.net!EU.net!usenet2.news.uk.psi.net!uknet!usenet1.news.uk.psi.net!uknet!uknet!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!sanger.ac.uk!pmr
From: pmr@sanger.ac.uk (Peter Rice)
Newsgroups: bionet.software.srs
Subject: Re: We want to help you to market your great software (which nobody knows about)
Date: 02 Oct 1996 08:32:46 GMT
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	<3250FA99.167E@embl-heidelberg.de>
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In-reply-to: Thure Etzold's message of Tue, 01 Oct 1996 13:03:53 +0200

In article <3250FA99.167E@embl-heidelberg.de> Thure Etzold <etzold@embl-heidelberg.de> writes:
>   >         Hey Thure, keep SRS free, I will pay you a beer next time
>   > we are in Heidelberg!
>   >                                         Francois.
>   > P.S.: Of course, one for Peter too...
>
>   no plans for commercialization yet - so i take your offer!
>   you could come to Hinxton next year - great chances to find me AND
>   Peter there;-)

But the beer is better in Heidelberg :-)

SRS: the first software in the pub domain ?!
--
------------------------------------------------------------------------
Peter Rice                           | Informatics Division,
E-mail: pmr@sanger.ac.uk             | The Sanger Centre,
Tel: (44) 1223 494967                | Wellcome Trust Genome Campus,
Fax: (44) 1223 494919                | Hinxton, Cambridge, CB10 1SA,
URL: http://www.sanger.ac.uk/~pmr/   | England

From owner-srs@net.bio.net Tue Oct 01 23:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!nntp.zit.th-darmstadt.de!fu-berlin.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs,embnet.general
Subject: Re: SRS will soon stop working :-)
Date: Wed, 02 Oct 1996 20:52:00 +0200
Organization: EMBL
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To: bioinfo@infobiogen.fr

Claude Scarpelli wrote:
> 
> We have noticed that most (all ?) SRS WWW sites around the world are
> configured such in a way that they are not compatible with the
> emergence of WWW cache.
> 
> When the browser's client is configured to use a WWW cache, the SRS
> queries issued by the user may be processed with another client
> parameters.
> 

Together with Rob Hooft from the EMBL we have looked at that problem in
detail:

We found alltogether three more or less practical options to turn off
caching:

1) include /cgi-bin/ in the URL
2) adding a 'Pragma:no-cache' header
3) adding a header with an expiry date, eg, "Expires: Thu, 01 Dec 1994
16:00:00 GMT"

the first we didn't like since it is quite 'clunky' and forces one to
put all cgi's into
a single directory (not just the one of SRSWWW).

options 2 and 3 both work well ...too well since they turn off cashing
by Netscape  
with the consequence that one has to reload always when going a page
back or forward in the
client.

However, consulting the internet standard RFC 1945 we found this:

   Applications must not cache responses to a POST request because the
   application has no way of knowing that the server would return an
   equivalent response on some future request.

Now in SRS5 the pages with user context that are generated by the server
are either POST requests - so they are not cashed - or if obtained by
GET have the user-ID in the URL which makes them unique from pages
retrieved by another user. 

All other page obtained by GET without the userId, eg, pages with single
entries, have no
user context and can be safely cached and shared among users.

As far as SRS5 is concerned the system should be safe as it is now.
The only page in SRS4 that is problematic is the one with the URL
http://server/srs/srsc
since it contains user context information but the userId is not
included in the URL.
So the best would be to add an expiry date + no cache pragma to the
header of just
that page. 

regards
Thure



-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Tue Oct 01 23:00:00 1996
Path: biosci!agate!howland.erols.net!newspump.sol.net!www.nntp.primenet.com!nntp.primenet.com!news.sgi.com!esiee.fr!jussieu.fr!univ-lyon1.fr!news.imag.fr!ciril.fr!u-strasbg.fr!news
From: Frederic PLEWNIAK <plewniak@igbmc.u-strasbg.fr>
Newsgroups: bionet.software.srs
Subject: Re: We want to help you to market your great software (which nobody knows about)
Date: Wed, 02 Oct 1996 11:12:53 +0200
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		<3250FA99.167E@embl-heidelberg.de> <PMR.96Oct2093246@unst.sanger.ac.uk>
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Peter Rice wrote:
> 
> SRS: the first software in the pub domain ?!
> 
Er???...
I thought it was DARTS (Dynamics Algorithms for Real-Time
Simulation)(*).
Fred


(*) http://robotics.jpl.nasa.gov/tasks/darts/homepage.html

From owner-srs@net.bio.net Tue Oct 01 23:00:00 1996
Path: biosci!agate!howland.erols.net!newspump.sol.net!www.nntp.primenet.com!nntp.primenet.com!enews.sgi.com!news.sgi.com!esiee.fr!jussieu.fr!univ-lyon1.fr!news.imag.fr!ciril.fr!usenet
From: pingouin@crystal.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.software.srs
Subject: Re: We want to help you to market your great software (which nobody knows about)
Date: 2 Oct 1996 09:03:22 GMT
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In article <PMR.96Oct2093246@unst.sanger.ac.uk>,
	pmr@sanger.ac.uk (Peter Rice) writes:

>But the beer is better in Heidelberg :-)

	Perhaps we can try Guiness...Then Des Higgins will come with,
perhaps.

>SRS: the first software in the pub domain ?!

	Yep, next bioinformatics meeting in a pub, somewhere...
(We all always put our softwares in the /ftp/pub directory, no?)

						Francois.
-- 
Francois Jeanmougin
Service de bioinformatique / bioinformatics service
IGBMC BP 163
67404 Illkirch France
tel : (33) 88 65 32 71
e-mail : jeanmougin@igbmc.u-strasbg.fr
"Tout ca m'est tergal, qu'il laine ou qu'il chandail" (STTELLLA)


From owner-srs@net.bio.net Wed Oct 02 23:00:00 1996
Path: biosci!agate!newsgate.duke.edu!news.duq.edu!newsfeed.pitt.edu!gatech!csulb.edu!news.sgi.com!nntp.coast.net!oleane!jussieu.fr!infobiogen.fr!not-for-mail
From: claude@lovelace.infobiogen.fr (Claude Scarpelli)
Newsgroups: bionet.software.srs,embnet.general
Subject: Re: SRS will soon stop working :-)
Date: 3 Oct 1996 12:40:00 +0200
Organization: GIS INFOBIOGEN, 7 rue Guy Moquet BP8, 94801 VILLEJUIF, France
Lines: 91
Message-ID: <530560$mih@lovelace.infobiogen.fr>
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In article <3252B9D0.446B@embl-heidelberg.de>,
Thure Etzold  <etzold@embl-heidelberg.de> wrote:
"  
"  Together with Rob Hooft from the EMBL we have looked at that problem in
"  detail:
"  
"  We found alltogether three more or less practical options to turn off
"  caching:
"  
"  1) include /cgi-bin/ in the URL
"  2) adding a 'Pragma:no-cache' header
"  3) adding a header with an expiry date, eg, "Expires: Thu, 01 Dec 1994
"  16:00:00 GMT"
"  
"  the first we didn't like since it is quite 'clunky' and forces one to
"  put all cgi's into
"  a single directory (not just the one of SRSWWW).

No. Just create a cgi-bin directory inside the SRS WWW directory. But
the URL must contained the (9 characters) string /cgi-bin/ somewhere,
not necessarely in the beginning.

I consider that storing the documents in one place, the gif images in
another one, and the cgi-bin in another is a good practice.

"  
"  options 2 and 3 both work well ...too well since they turn off cashing
"  by Netscape  
"  with the consequence that one has to reload always when going a page
"  back or forward in the
"  client.
"  

I have seen that. Sight:-(. This should be the good solution
though... Just keep it in mind, and use it as soon as browser will no
longer be brain damadged (see below):


"  However, consulting the internet standard RFC 1945 we found this:
"  
"     Applications must not cache responses to a POST request because the
"     application has no way of knowing that the server would return an
"     equivalent response on some future request.
"  

I don't think this paragraph applies to the 'BACK' button. However,
netscape think the opposite.


"  Now in SRS5 the pages with user context that are generated by the server
"  are either POST requests - so they are not cashed - or if obtained by
"  GET have the user-ID in the URL which makes them unique from pages
"  retrieved by another user. 
"  
"  All other page obtained by GET without the userId, eg, pages with single
"  entries, have no
"  user context and can be safely cached and shared among users.
"  
"  As far as SRS5 is concerned the system should be safe as it is now.

I agree.

"  The only page in SRS4 that is problematic is the one with the URL
"  http://server/srs/srsc
"  since it contains user context information but the userId is not
"  included in the URL.
"  So the best would be to add an expiry date + no cache pragma to the
"  header of just
"  that page. 
"  

It should be the best... except that it will break Netscape, from a
end-user point of vue (/cgi-bin/ in URL does not break netscape and
its 'back' button).

Put /cgi-bin/ somewhere in the URL appears to me as the only solution
avalaible today.


Regards,

-- 
------------------------------------------------------------------------------
Claude Scarpelli                        | Defenestrate: to exit a window
INFOBIOGEN ::= INFOrmatique appliquée à | onscreen. (Time International
l'étude des BIOmolécules et des GÉNomes	| Vol 146, No. 20, Nov 13, 1995)
-- 
------------------------------------------------------------------------------
Claude Scarpelli                        | Defenestrate: to exit a window
INFOBIOGEN ::= INFOrmatique appliquée à | onscreen. (Time International
l'étude des BIOmolécules et des GÉNomes	| Vol 146, No. 20, Nov 13, 1995)

From owner-srs@net.bio.net Sun Oct 06 23:00:00 1996
Path: biosci!agate!howland.erols.net!surfnet.nl!swidir.switch.ch!swsbe6.switch.ch!news.belnet.be!news.vub.ac.be!usenet
From: pinstall@sga.ulb.ac.be (Patrick Installe)
Newsgroups: bionet.software.srs,embnet.general
Subject: Re: SRS will soon stop working :-)
Date: Mon, 07 Oct 1996 13:18:47 GMT
Organization: Université Libre de Bruxelles
Lines: 33
Message-ID: <53b0bk$5i0@rc1.vub.ac.be>
References: <52quc2$15t@lovelace.infobiogen.fr> <52r5ha$s89@winx03.informatik.uni-wuerzburg.de>
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krasel@wpxx02.toxi.uni-wuerzburg.de (Cornelius Krasel) wrote:

>Claude Scarpelli (claude@lovelace.infobiogen.fr) wrote:
>[snip]

>> How can it be fixed ?
>> 
>> 1) configure the WWW cache to NOT cache URL containing srs/srsc. Not
>>    practicable, since user may not have enough authority to modify
>>    the configuration of the cache they are using.
>> 
>> 2) Configure the SRS site in such a way that the magic strings
>>    /cgi-bin/ appear in each URL. WWW cache never caches a document
>>    when the URL contains this magic string.
>> 
>> 3) Have wgetz send a protocol element (Pragma: no-cache) with each
>>    documents (especially the very first one). Cache will honor this
>>    information by not caching the document. Of course, it requires
>>    modification on the wgetz source code. We will ask the author to
>>    proceed this way, since it is the best way to communicate with a
>>    WWW cache

>4) Let the http server in question add a Last-Modified-Since: header
>   to its information.

5) I didn't follow all the technical detail but another way could
perhap's be the cookies ..
http://www.netscape.com/newsref/std/cookie_spec.html.

Have a nice day

Patrick Installe (pinstall@sga.ulb.ac.be)


From owner-srs@net.bio.net Sun Oct 06 23:00:00 1996
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!metro!metro!inferno.mpx.com.au!news.unimelb.EDU.AU!wehi.edu.au!wehi!janice
From: janice@wehi.edu.au (Janice Coventry, Walter and Eliza Hall Institute)
Newsgroups: bionet.software.srs
Subject: Genbank indexing
Date: 7 Oct 96 16:17:31 +1000
Organization: Walter & Eliza Hall Institute
Lines: 25
Message-ID: <1996Oct7.161731@wehi>
NNTP-Posting-Host: wehiu.wehi.edu.au

Hi

It came to my attention that my indexing of Genbank was incorrect for the 
current version, and after some investigation I realized that the problem
is when keywords extend over more than one line.  For example if you looked for
sequence HSU30473 you returned the correct description with the incorrect
sequence attached.   And searching gave incorrect results for some searches.
To fix this problem I have changed keywords definition from:
keywords = [keyword { ';' keyword}] ['.'];

to

keywords = {keyword {';' [keyword]}} ['.'];

Janice
-- 

================================================================================
Janice Coventry
The Walter and Eliza Hall Institute of Medical Research,
P.O. Royal Melbourne Hospital, Victoria, 3050, Australia.
Phone: International +61-3-9345-2586   FAX: International +61-3-9347-0852
            National 03-9345-2586                    National 03-9347-0852
Email:  janice@wehi.edu.au
===============================================================================

From owner-srs@net.bio.net Thu Oct 10 23:00:00 1996
Path: biosci!bcm.tmc.edu!cs.utexas.edu!www.nntp.primenet.com!nntp.primenet.com!news.sgi.com!esiee.fr!jussieu.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: Problem in SRS4
Date: Fri, 11 Oct 1996 15:32:19 +0200
Organization: INFOBIOGEN
Lines: 38
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CC: ETZOLD@embl-heidelberg.de

Hello,

I hope someone could help me to resolv my little problem :

As we have changed our SRS address in INFOBIOGEN for
"..srs/cgi-bin/srsc",
I have some trouble with the hyperlink file for the 
line #linkcall /id=%FETCH_CDS which require 132 car. max.
I have an error message when i run srssection:
> srssection
............
............
..............................................................
.......e__parnotok, parameter does not meet constraints
Line nr. 58 in file /env/infobiogen/pack/srs/odd/hyperlink.sdl
Attribute: call, string: <a
href=/srs/cgi-bin/srsc?[%s-id:%s]||-subn||%d||-sf||%
s>CDS</a>_<a
href=/srs/cgi-bin/srsc?[%s-id:%s]||-subn||%d||-sf||%s||-tr>Pept</a>
, maxlen: 132

I increase MSGxXLN in msg.h and SDLxXASSGSTR in sdl.h but nothing
happended.

If someone have a clue on how to change the max length for the attribut
linkCall, please reply me


Thanks for your help in advance,

-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Fri Oct 11 23:00:00 1996
Path: biosci!agate!howland.erols.net!www.nntp.primenet.com!nntp.primenet.com!nntp.uio.no!nntp.zit.th-darmstadt.de!fu-berlin.de!zrz.TU-Berlin.DE!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: srs5.03b ...some more
Date: Sat, 12 Oct 1996 14:26:32 +0200
Organization: EMBL
Lines: 26
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...forgot to mention that the path for SRS' cgi dir is still

/srsbin/ but if you do 

srsinstall www
you will be asked for a path where /srsbin/ is the default. So 
following the discussion of how to prevent caching you should
enter

/srs/cgi-bin/ 

instead and then make a ScriptAlias for /srs/cgi-bin/. 

I haven't tested it yet but it should work - and of course
I would be interested to get feed back on that.

regards
Thure


-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Fri Oct 11 23:00:00 1996
Path: biosci!agate!howland.erols.net!www.nntp.primenet.com!nntp.primenet.com!nntp.uio.no!nntp.zit.th-darmstadt.de!fu-berlin.de!zrz.TU-Berlin.DE!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: new release srs5.03
Date: Sat, 12 Oct 1996 14:20:49 +0200
Organization: EMBL
Lines: 102
Distribution: world
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A new release of srs5 is ready and can be ftp'ed from

ftp://felix.embl-heidelberg.de/pub/databases/trembl/srs5_03b.tar.gz

I append here the release notes

regards
Thure

--------------------------------------------------------------------
SRS release 5.03b
=================

This is the beta release of SRS 5.0 which has been compiled and tested
on
IRIX 5.x, IRIX 6.x (32-bit binary), OSF1 2.x, 3.x, 4.x, Linux 2.x and
ULTRIX 4.x. It could also work on AIX, HP-UX, IRIX 6.x (64-bit binary),
Solaris, SunOS.

If installing on Linux, you will have no csh and so you should remove
the -e
flag on the first line of the file srs/srsinstall.

First a list of what is still missing:

  1) the GCG formatted databanks are still not supported
  2) extraction of subentries (eg, sequence features) is not
     yet possible

Both items are being worked on and will be hopefully released in the
next
version which will then be without the 'b'.

Now the new things:
===================

1) The .is files can now run as an independent script and used by
   SRS without changing the script.
   So in 'tfsite.is' the 'entry' production must always have
$In:[file:text]
   
   entry:   ~ {$In:[file:text] $Out}
              ('AC' {$Not} ln)*
              ('AC  ' {$entryFip=$Fip $Wrt} ln {$App} 
               ('AC' {$Not} ln {$App})+)?
            ~
   
   and the code for testing at the end must use "$TestMode" 
   
   
   if:$TestMode {
     $job = $JobNew:[prod:$rules skip:" "
fileName:'/data/transfac/site.dat']
     while:$JobTokens:[$job name:id print:1] {
       $JobNext:$job
       $print:"-------->entry\n" 
     }
   }
   
2) There is now a very simple Icarus debugger. It is by no means ready
but
   even at this stage really useful. It is documented in chapter 6 in
the
   WWW manual. 
   
3) I modified the information pages for databanks and data-fields in 
   SRSWWW. Have a look at .it files in 'SRSDB:' which have the
description
   about the databanks and fields which is placed into these pages.
   The library information page has the links to the .i, .it, .is
   files for each databank (btw, our test server is 
   'http://kappa.embl-heidelberg.de:8000/srs/'). The idea is that every 
   databank should be documented by a .it file.
   
4) There is an emacs lisp file in 'SRSETC:' which defines an Icarus mode
-
   defines only coloring with fontlock. I don't know enough emacs lisp
to wri
   a proper mode with automatic indentation etc. - any volunteers?
   
5) The indexing of databank partitions runs stable now. This means that
   big databanks like genbank and EMBL can be indexed in chunks of eg, 
   100000 entries and then later merged. srscheck takes care of all
   necessary commands. Have a look in embl.i: attribute 'partSize' of 
   $library sets the partitioning. With a part size of 100000 the
indexing
   of EMBL on an alpha takes less than 50mbyte memory.


--

Thure Etzold, etzold@embl-heidelberg.de
Johnathon Weare, weare@embl-heidelberg.de
10. October, 1996


-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Fri Oct 11 23:00:00 1996
Path: biosci!agate!howland.erols.net!newsfeed.internetmci.com!in3.uu.net!news.idt.net!news
From: captroy@mail.idt.net (J. Roy Cash)
Newsgroups: bionet.software.srs
Subject: SBase Data Analyst  for PA contract
Date: Sat, 12 Oct 1996 21:42:19 GMT
Organization: The RED HOOK TECHNOLOGY GROUP...www.rht.com
Lines: 11
Message-ID: <53p36h$g2o@News.IDT.NET>
Reply-To: captroy@mail.idt.net
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We are staffing a contract position for an Sbase Data Analyst with 5
years of experience for a 3-6 month contract in the Philly area. DSS
knowledge and Visual Basic application development are necessary. This
is essentially a DBA type of position. Open Immediately. Call or email
Roy at 516 724 7300 ext 104
J.Roy Cash
The Red Hook Technology Group
(516)724 7300 ext 104
(516)724 8587 (Fax)
http://www.rht.com


From owner-srs@net.bio.net Fri Oct 18 23:00:00 1996
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.software.srs
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 19 Oct 1996 02:00:44 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 239
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199610190900.CAA12047@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net

From owner-srs@net.bio.net Mon Oct 21 23:00:00 1996
Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!news.mathworks.com!uunet!in1.uu.net!news.u.washington.edu!pogo!evolution
From: "Spenser Barlow" <sbarlow@localaccess.com>
Newsgroups: bionet.software.srs,sci.bio.ecology,sci.bio.entomology,sci.bio.entomology.homoptera,sci.bio.entomology.lepidoptera,sci.bio.entomology.misc,sci.bio.ethology,sci.bio.fisheries,sci.bio.food-science,sci.bio.herp,sci.bio.microbiolo
Subject: Watson & Crick '96 High School Fund Raiser
Date: 22 Oct 96 07:44:32 GMT
Organization: University of Washington
Lines: 67
Message-ID: <01bbc050$a3815760$263040ce@sbarlow>
NNTP-Posting-Host: pogo.cqs.washington.edu
X-Newsreader: Microsoft Internet News 4.70.1155
X-Mailedby: NT SMTP/LISTSERVER v2.11 (ntmail@net-shopper.co.uk)
Status: R
Originator: evolution@pogo
Xref: biosci bionet.software.srs:327 sci.bio.ecology:21405 sci.bio.entomology.homoptera:164 sci.bio.entomology.lepidoptera:5160 sci.bio.entomology.misc:3702 sci.bio.ethology:3543 sci.bio.fisheries:2432 sci.bio.food-science:3654 sci.bio.herp:7025

---WATSON & CRICK in '96---

Note: This is an advertisement for a HILARIOUS and MOCKING T-shirt.
The cost is $15, and we have approximately 75 T-shirts left. SO ORDER SOON!

The money is being raised to fund a high-school biotechnology class in
Centralia, WA, so this is a worthwhile cause.

If you are interested read on. If you are not interested, read on - this
ad is quite funny.

In case you don't trust us to send you a T-shirt after we receive your
money, we welcome you to call us at (360) 736-2146 or E-mail us at
docdna@localaccess.com. If that still does not satisfy your fears, I have
no idea what you can do and, therefore, you should probably not order from
us.

ATTENTION: All Molecular Biologists w/money, Geneticists w/money,
Biochemists w/money, Microbiologists w/money, Biologists w/money, Science
Teachers w/money, Teachers w/money, Biology Students w/money, Students
w/money, General Public interested in Genetics w/money, General Public
w/money, Dogs of the above people w/money, Goldfish of the above people
w/money, Small Furry Animals named Ralph w/money, Small Furry Animals not
named Ralph w/money, etc.

        I think you get the picture. We do not care who you are - just that
you
have money. In otherwords, we want your money.

        Now, a logical and sane human being might say NO to sending money
to
complete strangers. However, we know most BIOLOGISTS and CHEMISTS are NOT
SANE. Still, just so you don't look like a fool when your friends ask you
why you are sending off $15 dollars to people you don't know, we WILL send
you a stylish t-shirt so you can gloat in those doubting Thomas' faces.

        The Shirt features a blue and red field separated by a white
double-helix. On the top red field Watson is emblazoned and on the bottom
blue field
Crick is labeled. A white "96" is positioned on the right side of the
double-helix which stops the helix from reaching the far right side of the
T-shirt. See .jpg file attachment.

HOW TO ORDER:

To order, send a SASE w/check or cash to the order of $18.00  ($15 + $3
shipping) to:

Henri Weeks
919 W. Reynolds Ave.
Centralia, WA 98531

Option #2:  We can ship the shirt COD (check or money order). Write, call,
or e-mail us to initiate shipping.

All checks must be made out to Henri Weeks.  

You should receive your order just as soon as the US Mail service or UPS
can get
it to you.

Thank-you for you time.
By sbarlow@localaccess.com





From owner-srs@net.bio.net Tue Oct 29 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!newsfeed.sunet.se!news00.sunet.se!sunic!news.sprintlink.net!news-peer.sprintlink.net!howland.erols.net!news3.cac.psu.edu!news.cse.psu.edu!rutgers!mcrcr6!cmcl2!news.nyu.edu!mcrcr1.med.nyu.edu!user
Newsgroups: bionet.software.gcg,bionet.software.srs
Subject: searching in comment field
Message-ID: <browns02-3010961305560001@mcrcr1.med.nyu.edu>
From: browns02@mcrcr.med.nyu.edu (Stuart M. Brown)
Date: Wed, 30 Oct 1996 13:05:56 -0500
Organization: NYU-MC Research Computing Resource
NNTP-Posting-Host: mcrcr1.med.nyu.edu
Lines: 18
Xref: biosci bionet.software.gcg:2057 bionet.software.srs:329

We are doing a bunch of BLAST searches with the EST database.

I just got an idea - since these est's are routinely BLASTed
before they are submitted- and these results are generally noted
in the comment field, why can't I search the EST database for
comments that mention BLAST hits against my sequences of interest?

I've tried LOOKUP- but the "All text" field does not appear to
include the comment field of the GenBank entry.  I also
tried ENTREZ with only a bit more success - yet I can see mentions
of my sequence in the comments when I do my own BLAST searches and 
then read the full annotation of the ESTs that we hit.

-- 
Stuart M. Brown, Molecular Biology Consultant 
NYU-MC Research Computing Resource, Dept. of Cell Biology
550 First Ave, New York, NY 10016
Phone: (212)263-7689  FAX: (212)263-8139

From owner-srs@net.bio.net Tue Oct 29 22:00:00 1996
Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!vixen.cso.uiuc.edu!news.indiana.edu!news
From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software.gcg,bionet.software.srs
Subject: Re: searching in comment field
Date: 30 Oct 1996 23:40:54 GMT
Organization: Biology, Indiana University - Bloomington
Lines: 31
Message-ID: <558p26$pgc@dismay.ucs.indiana.edu>
References: <browns02-3010961305560001@mcrcr1.med.nyu.edu>
NNTP-Posting-Host: chipmunk.bio.indiana.edu
Xref: biosci bionet.software.gcg:2059 bionet.software.srs:330

Stuart,

This may be a function of how SRS (or the GCG variant Lookup) is
configured at a particular server.  At IUBIo Archive, I revised the 
indexing for SRS to make sure the Genbank comment fields were
searchable.  As a test of your question, I just now searched
the Genbank EST section at IUBIo, searching "Comment" fields
for "BLAST", and found 165 matches.

Feel free to use this SRS server for Genbank lookups. 
  http://iubio.bio.indiana.edu:81/srs/srsc

- Don

In article <browns02-3010961305560001@mcrcr1.med.nyu.edu>,
Stuart M. Brown <browns02@mcrcr.med.nyu.edu> wrote:
>We are doing a bunch of BLAST searches with the EST database.
>
>I just got an idea - since these est's are routinely BLASTed
>before they are submitted- and these results are generally noted
>in the comment field, why can't I search the EST database for
>comments that mention BLAST hits against my sequences of interest?
>
>I've tried LOOKUP- but the "All text" field does not appear to
>include the comment field of the GenBank entry.  I also
>tried ENTREZ with only a bit more success - yet I can see mentions
>of my sequence in the comments when I do my own BLAST searches and 
>then read the full annotation of the ESTs that we hit.
>
--
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-srs@net.bio.net Wed Oct 30 22:00:00 1996
Path: biosci!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: indexing Genbank 97 from gcg format
Date: Thu, 31 Oct 1996 12:10:16 +0000
Organization: SEQNET
Lines: 35
Distribution: bionet
Message-ID: <32789728.41C6@dl.ac.uk>
NNTP-Posting-Host: s-ind2.dl.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0Gold (X11; I; IRIX 5.3 IP12)

Hi folks,

Has anybody been able to index genbank 97 from gcg formatted files ? -
For me indexing keeps falling over on entry HSHLAK1 in the primates
section. 
The error message I get is:
e__nammismatch, names are not identical
"HSHLAK1" and "C"

It does not occur with the plain genbank files. It can't have anything
to do with the size of genbank, as it also occurs if I restrict 
genbank to the primates section. As far as I can tell the gcg
seq and ref file are completely normal for this entry.
srsbuild is apparently supposed to produce this error message if
the names in the ref and seq files are not the same, but as far as I
can tell they are the same, and I really don't understand were this "C"
in the error message comes from.

Any ideas ?

-- 
---------------------------------------------------------------------------
|  Martin Hilbers          |       E-mail:
m.p.hilbers@dl.ac.uk           |
|  SEQNET                  |       Tel:   
+44-1925-603492                |
|  Daresbury Laboratory    |       Fax:   
+44-1925-603100                |
|  Daresbury, Warrington  
|----------------------------------------------|
|  Cheshire WA4 4AD        |    SEQNET is the UK national EMBNet
node     |
|  United Kingdom          |   
http://www.dl.ac.uk/SEQNET/home.html      |
---------------------------------------------------------------------------

