From owner-srs@net.bio.net Fri Dec 06 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!online.no!sn.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!howland.erols.net!EU.net!main.Germany.EU.net!news-koe1.dfn.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs,bionet.software
Subject: New release 5.0 of SRS
Date: Sat, 07 Dec 1996 01:25:48 +0100
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Dear all,

SRS5 is finally out! ...this time it is the full release and not a
'beta'

you can get it from 

 ftp://ftp.embl-heidelberg.de/pub/databases/trembl/srs5_0.tar.gz

Those are the changes since the last beta (srs5.04b):

o The indexing works now with databanks in native or GCG format. 
o There is now support for sequence features 
o srscheck and srsbuild have been revised and work as in SRS4. This
  includes the -r, -t and -rel options of srsbuild.
o Parsers have been written for many more databanks.
o Documentation is much better (Icarus manual, Guided tour).
o All installation scripts have been rewritten as Bourne shell scripts. 

SRS5 is much more powerful but also more complicated as SRS4. A lot of 
parsers have still to be written, but those that are there can be used 
as templates for 'cut and paste' programming. Adding a new databank
needs
now three files that describe the structure (format, data-fields,
links), 
the syntax and the databank itself (Source, ftp address, contact
address, 
etc). This is described in the "Guided Tour" that comes with the 
distribution. 

We would like to invite you to write Icarus files and post them
to the newsgroup bionet.software.srs to make them available to others. 
We will then put the files into future releases of SRS.

For the installation of the SRSWWW server an Alias and a ScriptAlias are
needed. Following the discussion in this newsgroup about notifying the 
proxies not to cache we use now the ScriptAlias /srs5bin/cgi-bin/.
Please
tell us if that works. 

...more in the release notes

regards and happy installation


Giorgio Verde      verde@embl-heidelberg.de
Johnathon Weare    weare@embl-heidelberg.de
Thure Etzold       etzold@embl-heidelberg.de



-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Mon Dec 09 22:00:00 1996
Newsgroups: bionet.software.srs
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From: Tao Jiang <jiangt@pku.edu.cn>
Subject: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
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Date: Tue, 10 Dec 1996 01:32:23 GMT
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I downloaded the SRS version 5.0, and had a small test
yesterday. I installed only a very small part of EMBL
: phg.dat, and try to index it. To my surprising, I
found it would take me over 12 hours to index it (in fact,
the indexing hasn't finished yet), and too many index
files were generated: embl_fts_1.inx, embl_fts_2.inx, ...
, embl_569.inx, ... (I have modified srsdb.i and embl.i to
include only phg.dat of EMBL).

However, if I test it with swissprot, it seems to work well
(only one index file for every index).

Any suggestions and help are greatly appreciated.

-- 
Tao Jiang            Fax: 86-10-62751982
Network Center       Homepage: http://jiangt.pku.edu.cn/~jiangt/
Peking University    Email: jiangt@pku.edu.cn

From owner-srs@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!agate!howland.erols.net!EU.net!usenet2.news.uk.psi.net!uknet!usenet1.news.uk.psi.net!uknet!uknet!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!sanger.ac.uk!pmr
From: pmr@sanger.ac.uk (Peter Rice)
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: 10 Dec 1996 09:43:30 GMT
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References: <32ACBDA7.57D9066B@pku.edu.cn>
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In-reply-to: Tao Jiang's message of Tue, 10 Dec 1996 01:32:23 GMT

In article <32ACBDA7.57D9066B@pku.edu.cn> Tao Jiang <jiangt@pku.edu.cn> writes:
>   I downloaded the SRS version 5.0, and had a small test
>   yesterday. I installed only a very small part of EMBL
>   : phg.dat, and try to index it. To my surprising, I
>   found it would take me over 12 hours to index it (in fact,
>   the indexing hasn't finished yet), and too many index
>   files were generated: embl_fts_1.inx, embl_fts_2.inx, ...
>   , embl_569.inx, ... (I have modified srsdb.i and embl.i to
>   include only phg.dat of EMBL).
>
>   However, if I test it with swissprot, it seems to work well
>   (only one index file for every index).

The multiple index files are not a bug - they are a feature of SRS 5.0
(and a very welcome feature too).

SRS 4.0 needed to index all of EMBL in one go, which consumed terrible
amounts of memory.

SRS 5.0 splits EMBL into smaller chunks (defined in embl.i as
partSize:100000 for 100000 entries), and builds a separate index for
each.  There is a new "srsbuild -m" step which merges these smaller
indices together once they have been compressed.

Having said that, I seem to have problems with the EMBL indexing
too, so I am still checking on what is happening. After 82500+ entries
from est1, I get:

> SRSDB:embl.is:70: error: insufficient memory - error during malloc,
> could not allocate "Cursor object"

This was indexing the EMBL flat files.

Of course, we have both been editing the embl.i file (and some others)
so maybe we did something wrong.
--
------------------------------------------------------------------------
Peter Rice                           | Informatics Division,
E-mail: pmr@sanger.ac.uk             | The Sanger Centre,
Tel: (44) 1223 494967                | Wellcome Trust Genome Campus,
Fax: (44) 1223 494919                | Hinxton, Cambridge, CB10 1SA,
URL: http://www.sanger.ac.uk/~pmr/   | England

From owner-srs@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!sanger.ac.uk!pmr
From: pmr@sanger.ac.uk (Peter Rice)
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: 10 Dec 1996 13:22:18 GMT
Organization: The Sanger Centre
Lines: 39
Message-ID: <PMR.96Dec10132218@unst.sanger.ac.uk>
References: <32ACBDA7.57D9066B@pku.edu.cn> <PMR.96Dec10094330@unst.sanger.ac.uk>
NNTP-Posting-Host: unst.sanger.ac.uk
In-reply-to: pmr@sanger.ac.uk's message of 10 Dec 1996 09:43:30 GMT

In article <PMR.96Dec10094330@unst.sanger.ac.uk> pmr@sanger.ac.uk (Peter Rice) writes:
>In article <32ACBDA7.57D9066B@pku.edu.cn> Tao Jiang <jiangt@pku.edu.cn> writes:
>>   I downloaded the SRS version 5.0, and had a small test
>>   yesterday. I installed only a very small part of EMBL
>>   : phg.dat, and try to index it. To my surprising, I
>>   found it would take me over 12 hours to index it (in fact,
>   the indexing hasn't finished yet)
>
>   SRS 5.0 splits EMBL into smaller chunks (defined in embl.i as
>   partSize:100000 for 100000 entries), and builds a separate index for
>   each.  There is a new "srsbuild -m" step which merges these smaller
>   indices together once they have been compressed.
>
>   Having said that, I seem to have problems with the EMBL indexing
>   too, so I am still checking on what is happening. After 82500+ entries
>   from est1, I get:
>
>   > SRSDB:embl.is:70: error: insufficient memory - error during malloc,
>   > could not allocate "Cursor object"

I tracked down the problem. It was caused by srsbuild using more
memory (131Mb) than I had available.

Even reducing "partSize:100000" in embl.i failed to reduce this by much.

I have increased the limits (unlimit datasize) on the machine I used.
For your very slow runs, I assume that srsbuild is using more memory
than the machine has, and it has been swapping like crazy.

I guess this is connected with changes in EMBL indexing since the last
beta release (there have been several changes that could trigger it),
but that is something Thure is best able to answer.
--
------------------------------------------------------------------------
Peter Rice                           | Informatics Division,
E-mail: pmr@sanger.ac.uk             | The Sanger Centre,
Tel: (44) 1223 494967                | Wellcome Trust Genome Campus,
Fax: (44) 1223 494919                | Hinxton, Cambridge, CB10 1SA,
URL: http://www.sanger.ac.uk/~pmr/   | England

From owner-srs@net.bio.net Tue Dec 10 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Thure <etzold@embl-heidelberg.de>
Subject: Re: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32AEA3C2.41C6@embl-heidelberg.de>
Date: Wed, 11 Dec 1996 12:06:26 GMT
To: Tao Jiang <jiangt@pku.edu.cn>
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Tao Jiang wrote:
> 
> I downloaded the SRS version 5.0, and had a small test
> yesterday. I installed only a very small part of EMBL
> : phg.dat, and try to index it. To my surprising, I
> found it would take me over 12 hours to index it (in fact,
> the indexing hasn't finished yet), and too many index
> files were generated: embl_fts_1.inx, embl_fts_2.inx, ...
> , embl_569.inx, ... (I have modified srsdb.i and embl.i to
> include only phg.dat of EMBL).
> 

I am having with indexing GCG formatted EMBL as well and will fix it
this week. However, there seem to be no problems with the
original flat file version. To switch from gcg format to distributed
flat file edit embl.i and search all lines with a comment 'GCG format'

#  fileType:{@DAT_FILE @SEQ_FILE} #orig format
  fileType:{@GCGREF_FILE @GCGSEQ_FILE} #GCG format

flip around the comments so that you get

 fileType:{@DAT_FILE @SEQ_FILE} #orig format
#  fileType:{@GCGREF_FILE @GCGSEQ_FILE} #GCG format

then you must change the file names at the beginning of the file

$file:pro 

will have to change to

$file:em_pro

I included lists of both gcg file names and original names where one
list is always outcommented


regards
thure

From owner-srs@net.bio.net Tue Dec 10 22:00:00 1996
Path: biosci!agate!howland.erols.net!news-peer.gsl.net!news.gsl.net!EU.net!Ireland.EU.net!web3.tcd.ie!gen035.gen.tcd.ie!user
From: atlloyd@acer.gen.tcd.ie (Andrew T. Lloyd)
Newsgroups: bionet.software.srs
Subject: SRS 5_0 srsinstall all fails
Date: Wed, 11 Dec 1996 12:17:15 +0000
Organization: INCBI, Trinity College, Dublin 2, Ireland.
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Message-ID: <atlloyd-1112961217150001@gen035.gen.tcd.ie>
NNTP-Posting-Host: gen035.gen.tcd.ie

Hi Folks,

I get a rather strange error trying to srsinstall all:

(cc -Dosf -I/data/du5/srs/bin/osf  -g -D__ODD -DSRSINCLUDE=\"srs5.h\" -c -o \/ta
/du5/srs/bin/osf/seqdb.o  seqdb.c; ar r /data/du5/srs/bin/osf/libsrs.a \/datdu5/
srs/bin/osf/seqdb.o; )

/: write failed, file system is full
ar:  error writing archive member contents: No such file or directory
*** Exit 1
Stop.
There is an error: Stopping make procedure.

Surely 4GB is big enough, or is it some other file system which
is choked ?   variables: OSF1 v.3.2 make cc
 Any ideas gratefully considered.

Andrew

-- 
Andrew T. Lloyd  Irish National Centre for BioInformatics  INCBI
atlloyd@acer.gen.tcd.ie                   http://acer.gen.tcd.ie
Tel: (+353)-1-608-1969    EMBnet Ireland    Fax: (+353)-679-8558

From owner-srs@net.bio.net Tue Dec 10 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Thure <etzold@embl-heidelberg.de>
Subject: Re: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32AEC9DA.2781@embl-heidelberg.de>
Date: Wed, 11 Dec 1996 14:48:58 GMT
To: Tao Jiang <jiangt@pku.edu.cn>
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Tao Jiang wrote:
> 
> I downloaded the SRS version 5.0, and had a small test
> yesterday. I installed only a very small part of EMBL
> : phg.dat, and try to index it. To my surprising, I
> found it would take me over 12 hours to index it (in fact,
> the indexing hasn't finished yet), and too many index
> files were generated: embl_fts_1.inx, embl_fts_2.inx, ...
> , embl_569.inx, ... (I have modified srsdb.i and embl.i to
> include only phg.dat of EMBL).
> 
> However, if I test it with swissprot, it seems to work well
> (only one index file for every index).
> 
> Any suggestions and help are greatly appreciated.

I found the bug, in fact there were two: 

1) edit file src/icarus.c

after line 670 you find 

    if (!IcaCursorIsInput (job->inCursor, job->cursor)) {
/*      CursorDelete (&job->cursor); */
      job->cursor = NULL;

    }

remove the comments and rebuild srsbuild:

srsmake srsbuild

2) edit icarus/db/embl.is

around line 55 you find

  seq:       ~ (/.*2BIT *Len:/ /[0-9]+/ {$len=$Ct} ln ln 
	       {$s=$SeqGet2Bit:[$s file:$File len:$len]} ('>>>>'{$Not} ln)*|
               /.*ASCII/ ln ln ('>>>>' {$Not} /.*/ {$SeqApp:[$s
s:$Ct]})+) ~

change '$s=$SeqGet2Bit' to '$SeqGet2Bit'



regards
thure

From owner-srs@net.bio.net Tue Dec 10 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Thure <etzold@embl-heidelberg.de>
Subject: Re: SRS 5_0 srsinstall all fails
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32AEC7F0.167E@embl-heidelberg.de>
Date: Wed, 11 Dec 1996 14:40:48 GMT
To: "Andrew T. Lloyd" <atlloyd@acer.gen.tcd.ie>
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Andrew T. Lloyd wrote:
> 
> Hi Folks,
> 
> I get a rather strange error trying to srsinstall all:
> 
> (cc -Dosf -I/data/du5/srs/bin/osf  -g -D__ODD -DSRSINCLUDE=\"srs5.h\" -c -o \/ta
> /du5/srs/bin/osf/seqdb.o  seqdb.c; ar r /data/du5/srs/bin/osf/libsrs.a \/datdu5/
> srs/bin/osf/seqdb.o; )
> 
> /: write failed, file system is full
> ar:  error writing archive member contents: No such file or directory
> *** Exit 1
> Stop.
> There is an error: Stopping make procedure.
> 
> Surely 4GB is big enough, or is it some other file system which
> is choked ?   variables: OSF1 v.3.2 make cc
>  Any ideas gratefully considered.

hi andrew,

the 'ar' command writes temporary files into the /tmp directory and it
didn't find enough space there - you tell ar to write these files
somewhere else by defining the environment variable TMPDIR, eg,

setenv TMPDIR /trash/tmp


regards
thure

From owner-srs@net.bio.net Wed Dec 11 22:00:00 1996
Path: biosci!rutgers!uwm.edu!news-peer.gsl.net!news.gsl.net!EU.net!usenet2.news.uk.psi.net!uknet!usenet1.news.uk.psi.net!uknet!uknet!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!sanger.ac.uk!pmr
From: pmr@sanger.ac.uk (Peter Rice)
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: 12 Dec 1996 10:34:59 GMT
Organization: The Sanger Centre
Lines: 22
Message-ID: <PMR.96Dec12103459@unst.sanger.ac.uk>
References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de>
	<32AF65E2.36601FB1@pku.edu.cn>
NNTP-Posting-Host: unst.sanger.ac.uk
In-reply-to: Tao Jiang's message of Thu, 12 Dec 1996 01:54:42 GMT

In article <32AF65E2.36601FB1@pku.edu.cn> Tao Jiang <jiangt@pku.edu.cn> writes:
>   I modified the file icarus.c, embl.i and embl.is just
>   as Thure suggested and compiled icarus.c and run 'srssection'
>   and 'srsupdate', but it still blocks (maybe it will ends
>   after a very long time?).

The changes worked for me. Memory usage dropped dramatically, at least
in the early stages (then I went home, and it was finished this morning).
Maybe something went wrong with the "srsmake srsbuild" step? Or else you
really have very little memory on your system.

Our SRS 5.0 server will be available next week.

I am still busy exploring the icarus files. I expect to be changing the
indexing methods, and adding new databases, frequently for some time yet.
--
------------------------------------------------------------------------
Peter Rice                           | Informatics Division,
E-mail: pmr@sanger.ac.uk             | The Sanger Centre,
Tel: (44) 1223 494967                | Wellcome Trust Genome Campus,
Fax: (44) 1223 494919                | Hinxton, Cambridge, CB10 1SA,
URL: http://www.sanger.ac.uk/~pmr/   | England

From owner-srs@net.bio.net Wed Dec 11 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!rutgers!uwm.edu!cs.utexas.edu!www.nntp.primenet.com!nntp.primenet.com!su-news-hub1.bbnplanet.com!news.bbnplanet.com!cpk-news-hub1.bbnplanet.com!EU.net!usenet2.news.uk.psi.net!uknet!usenet1.news.uk.psi.net!uknet!uknet!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Tao Jiang <jiangt@pku.edu.cn>
Subject: Re: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32AF65E2.36601FB1@pku.edu.cn>
Date: Thu, 12 Dec 1996 01:54:42 GMT
To: Thure <etzold@embl-heidelberg.de>
Content-Type: multipart/mixed; boundary="------------1357101B5F987D624118B159"
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This is a multi-part message in MIME format.

--------------1357101B5F987D624118B159
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit

I am not sure if I am missing something here,
but I always have problems with SRS5.0.

I want to test with only phg.dat of EMBL,
which is a very small data file. With SRS4.08,
indexing takes only 1 min., while with SRS5.0,
it will take too long for me to wait it ends.
I modified the file icarus.c, embl.i and embl.is just
as Thure suggested and compiled icarus.c and run 'srssection'
and 'srsupdate', but it still blocks (maybe it will ends
after a very long time?).

I attach my embl.i, embl.is at the end, and any suggestions
are greatly appreciated.

-- 
Tao Jiang            Fax: 86-10-62751982
Network Center       Homepage: http://jiangt.pku.edu.cn/~jiangt/
Peking University    Email: jiangt@pku.edu.cn

--------------1357101B5F987D624118B159
Content-Type: text/plain; charset=us-ascii; name="embl.i"
Content-Transfer-Encoding: 7bit
Content-Disposition: inline; filename="embl.i"

#~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
#
#    $RCSfile: embl.i,v $
#    $Revision: 1.11 $
#    $Date: 1996/12/06 22:17:37 $
#    $Author: etzold $
#
#~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

#EMBLNEW_DB:$library:[EMBLNEW group:@SEQUENCE_LIBS 
#  format:@EMBL_FORMAT cachesize:2048 maxNameLen:15 
#  subentries:@EmblnewFeatures_DB
#  files:$file:emnew
#]

EMBL_DB:$library:[EMBL group:@SEQUENCE_LIBS 
  partSize:1000000
  comment:"  Nucleotide Sequence Database from EBML"
  subentries:@EmblFeatures_DB
  format:@EMBL_FORMAT 
  cachesize:2048 
  maxNameLen:30 files:{
#    $file:est1
#    $file:est2
#    $file:est3
#    $file:est4
#    $file:est5
#    $file:est6
#    $file:est7
#    $file:fun
#    $file:gss
#    $file:hum1
#    $file:hum2
#    $file:inv
#    $file:mam
#    $file:org
#    $file:patent
#    $file:phg
#    $file:pln
#    $file:pro
#    $file:rod
#    $file:sts
#    $file:syn
#    $file:unc
#    $file:vrl
#    $file:vrt 


#    $file:em_est1
#    $file:em_est2
#    $file:em_est3
#    $file:em_est4
#    $file:em_est5
#    $file:em_est6
#    $file:em_est7
#    $file:em_ba
#    $file:em_fun
#    $file:em_gss
#    $file:em_hum1
#    $file:em_hum2
#    $file:em_in
#    $file:em_om
#    $file:em_or
#    $file:em_ov
#    $file:em_pat
    $file:em_ph
#    $file:em_pl
#    $file:em_pr
#    $file:em_ro
#    $file:em_sts
#    $file:em_sy
#    $file:em_un
#    $file:em_vi
  }
]

EMBL_FORMAT:$libformat:[syntax:@EMBL_SYNTAX 
  fileType:{@DAT_FILE @SEQ_FILE} #orig format
#  fileType:{@GCGREF_FILE @GCGSEQ_FILE} #GCG format
  fields:{
    $field:[@DF_ID code:id index:id indexToken:id]
    $field:@DF_ALL
    $field:[@DF_Accession code:acc index:str indexToken:acc 
      tableToken:acc tableFormat:left]
    $field:[@DF_Division code:id index:str indexToken:div
      tableToken:div tableFormat:left]
    $field:[@DF_Molecule code:id index:str indexToken:mol
      tableToken:mol tableFormat:left]
#    $field:[@DF_DBOrigin code:acc index:str indexToken:dbOri
#      tableToken:dbOri tableFormat:left]
#    $field:[@DF_AccessionKey code:acc index:str indexToken:accKey
#      tableToken:accKey tableFormat:center]
    $field:[@DF_Description code:des index:str indexToken:des
      tableToken:t_des tableFormat:left]
    $field:[@DF_Keywords code:key index:str indexToken:key
      tableToken:key tableFormat:left]
    $field:[@DF_Organism code:org index:str indexToken:org]
    $field:[@DF_Authors code:ra index:str indexToken:authors
      tableToken:authors tableFormat:left]
    $field:[@DF_Date code:date index:int indexToken:date 
      tableToken:date tableFormat:center]
    $field:[@DF_SeqLength code:sq  index:int indexToken:seqLen 
      tableToken:seqLen tableFormat:right]
    $field:[@DF_LINK code:dr]
#    $field:[@DF_DNASequence token:gcgseq format:embl] #GCG format
    $field:[@DF_DNASequence token:sequence format:embl] #orig format

    $field:[@DF_HeaderField name:'Feature Table Fields']
    $field:[@DF_FtKey code:ft index:str indexToken:ftKey 
      indexId:@SUBENTRY_ID tableToken:ftKey tableFormat:left]
    $field:[@DF_FtQualifier code:ft index:str indexToken:ftQual
      indexId:@SUBENTRY_ID]
    $field:[@DF_PID code:ft index:str indexToken:pid
      indexId:@SUBENTRY_ID]
    $field:[@DF_FtDescription code:ft index:str indexToken:ftDes 
      indexId:@SUBENTRY_ID]
    $field:[@DF_FtSource code:ft index:str indexToken:ftSrc
      indexId:@SUBENTRY_ID]
    $field:[@DF_ChrsNo code:ft index:str indexToken:chrsNo 
      indexId:@SUBENTRY_ID]
    $field:[@DF_FtMap code:ft index:str indexToken:map
      indexId:@SUBENTRY_ID]
  }
]


EMBL_SYNTAX:$syntax:[file:"SRSDB:embl.is" ignore:" \t"]
$syntax:[name:ftseq file:"SRSDB:ftseq.is" ignore:" \t\n"]

#$link:[@EMBL_DB to:@?GENBANK_DB   toField:@DF_ACCNO]
#$link:[@EMBL_DB to:@?PIR_DB       toField:@DF_ACCNO]
#$link:[@EMBL_DB to:@?REBASE_DB    toField:@DF_ID]
#$link:[@EMBL_DB to:@?OMIM_DB      toField:@DF_ID]
#$link:[@EMBL_DB to:@?MEDLINE_DB   toField:@DF_ID]


EmblFeatures_DB:$library:[EMBL_features format:@EmblFeature_Format]
EmblnewFeatures_DB:$library:[EMBLNEW_features format:@EmblFeature_Format]

EmblFeature_Format:$libformat:[syntax:@EMBL_SYNTAX  #idType:@SUBENTRY_ID
  tableFormat:left
  fields:{
    $field:[@DF_ID token:ftId]
#    $field:[@DF_Accession code:acc fromParent:y]
#    $field:[@DF_Description code:des fromParent:y]

    $field:[@DF_FtKey token:ft tableToken:'t_ft|key']
    $field:[@DF_FtQualifier token:ft tableToken:'t_ft|qual']
    $field:[@DF_PID token:ft tableToken:'t_ft|db_xref']
    $field:[@DF_FtDescription token:ft tableToken:'t_ft|note']
    $field:[@DF_FtGene token:ft tableToken:'t_ft|gene']
    $field:[@DF_FtProduct token:ft tableToken:'t_ft|product']
    $field:[@DF_FtPartial token:ft tableToken:'t_ft|partial']
    $field:[@DF_FtPseudo token:ft tableToken:'t_ft|pseudo']
    $field:[@DF_FtNumber token:ft tableToken:'t_ft|number']
    $field:[@DF_FtSource token:ft tableToken:ftSrc]
    $field:[@DF_ChrsNo token:ft tableToken:'t_ft|chromosome'] 
    $field:[@DF_FtMap token:ft tableToken:'t_ft|map']
    $field:[@DF_DNALocation token:ftLocat tableFormat:listing]
  }
]

DF_FtGene:$srsfield:[Gene short:gen]
DF_FtProduct:$srsfield:[Product short:pro]
DF_FtPartial:$srsfield:[Partial short:par]
DF_FtPseudo:$srsfield:[Pseudo short:pse]
DF_FtNumber:$srsfield:[Number short:num]

--------------1357101B5F987D624118B159
Content-Type: text/plain; charset=us-ascii; name="embl.is"
Content-Transfer-Encoding: 7bit
Content-Disposition: inline; filename="embl.is"

#!/bin/env icarus
#~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
#    $RCSfile: embl.is,v $
#    $Revision: 1.10 $
#    $Date: 1996/12/06 22:17:38 $
#    $Author: etzold $
#
#~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

$rules={
  entry:     ~ {$In:[file:text] $Out  pre $Skip:0}
               ('ID  ' {$not} ln)*
               ('ID   '{$entryFip=$Fip $Wrt} ln {$App} 
                (/(  |ID|>>)/ {$Not} ln {$App})+ )? ~


  # data fields
  fields:    ~ {$In:entry $Out $Skip:1}
               id sep acc sep nid sep date sep f_des sep f_key sep 
               (src tax? sep f_org? sep)+ (rn rc? rp? rx? ra rt? rl? sep)* 
               link? sep (cmnt sep)* (fh f_ft*)? sep sq  
             ~
  sep:       ~ {$Wrt:sep} ('XX' ln)* ~ 
  id:        ~ {$Wrt:id}       'ID' / *([A-Z0-9_]+)/
               {$entryName=$1} ln ~
  acc:       ~ {$Wrt:acc}      ('AC' ln)+ ~
  nid:       ~ {$Wrt:nid}      ('NI' ln)* ~
  date:      ~ {$Wrt:date}     ('DT' ln)+ ~
  f_des:     ~ {$Wrt:des}      ('DE' ln)+ ~
  src:       ~ {$Wrt:org}      ('OS' ln)+ ~  
  tax:       ~ {$Wrt:org}      ('OC' ln)+ ~  
  f_org:     ~ {$Wrt:org}      ('OG' ln)+ ~  
  rn:        ~ {$Wrt:rn}       ('RN' ln)+ ~
  rc:        ~ {$Wrt:rc}       ('RC' ln)+ ~
  rp:        ~ {$Wrt:rp}       ('RP' ln)+ ~
  rx:        ~ {$Wrt:rx}       ('RX' ln)+ ~
  ra:        ~ {$Wrt:ra}       ('RA' ln)+ ~
  rt:        ~ {$Wrt:rt}       ('RT' ln)+ ~
  rl:        ~ {$Wrt:rl}       ('RL' ln)+ ~
  cmnt:      ~ {$Wrt:cmnt}     ('CC' ln)+ ~
  link:      ~ {$Wrt:link}     ('DR' ln)+ ~
  f_key:     ~ {$Wrt:key}      ('KW' ln)* ~
  fh:        ~ {$Wrt:fh}       ('FH' ln)+ ~
  f_ft:      ~ {$Wrt:ft}       'FT' ln ('FT     ' ln)* ~
  sq:        ~ {$Wrt:sq}       'SQ' ln ~


  # parsing the sequence part from separate stream
  gcgseq:    ~ { $In:[file:seq] $Out pre $s=$SeqNew
                 $SeqMake:$s $Wrt:[s:$entryName]
               }
               '>>>>' {$seqFip=$Fip} (/[A-Z0-9]+/ seq |  
               /[A-Z0-9]+_0/ seq (/>>>>[A-Z0-9]+_[1-9]+/ 
               {$SeqTrunc:[$s len:10000]} seq)+) ~ 
  seq:       ~ (/.*2BIT *Len:/ /[0-9]+/ {$len=$Ct} ln ln 
	       {$SeqGet2Bit:[$s file:$File len:$len]} ('>>>>'{$Not} ln)*|
               /.*ASCII/ ln ln ('>>>>' {$Not} /.*/ {$SeqApp:[$s s:$Ct]})+) ~

  sequence:  ~ {$In:[file:seq share:text] $Out pre {$s=$SeqNew $seqFip=$Fip} 
                $Wrt:[s:$entryName] $SeqMake:$s} 
               ('ID' {$Not} ln {$SeqApp:[$s s:$Ct]})* ~


  # for indexing
  i_id:      ~ {$In:[entry] $Out:id} /ID +/ name {$Wrt} ~
  i_div:     ~ {$In:[fields c:id] $Out:div}
                /ID +/ name  /[^;]+/ ';' /[^;]+/ ';' name {$Wrt} ~
  i_mol:     ~ {$In:[fields c:id] $Out:mol} 
               /ID +/ name  /[^;]+/ ';' /[^;]+/  {$Wrt} ~
  i_acc:     ~ {$In:[fields c:acc] $Out:acc} ('AC' (name {$Wrt} ';')+)+  ~
  i_nid:     ~ {$In:[fields c:nid] $Out:nid} 'NI' name {$Wrt}  ~
  i_dates:   ~ { $In:[fields c:date] $Out:date 
                 init $month={JAN:1 FEB:2 MAR:3 APR:4 MAY:5 JUN:6 JUL:7 AUG:8 
                              SEP:9 OCT:10 NOV:11 DEC:12}
               }
               /.* ([0-9]+)-([A-Z]+)-([0-9]+)[^\n]+Cre/ 
               {$Wrt:[credate s:($1 + $month.$2*100 + $3*10000)]} ~
  des:       ~ {$In:[fields c:des] $Out} 
               ('DE' (/\\(EC *([0-9]+\\.[0-9]+\\.[0-9]+\\.[0-9]+)/
               {$Wrt:[s:$1]}| word{$Wrt} | sp)+ ln)+ ~ 
  org:       ~ {$In:[fields c:org] $Out} 
               ('OC' (/[^;.\n]+/ {$Wrt} | /[^\n]/)*)+ |
                'OS' /[^(\n]+/ {$Wrt:[s:$Trim:$Ct]} 
                ('(' (/[^ \n)]+/ | /[^)]/)+)? |
                'OG'  /[^\n;.]+/ {$Wrt} ~
  key:       ~ {$In:[fields c:key] $Out} 
               ('KW' (/[^\n;.]+/ {$Wrt} | /[^\n]/)+)+ ~ 
  i_authors: ~ {$In:[fields c:ra] $Out:authors}
               (/RA/ (/([^.,\n]+) +([^,;\n]+)/ {$Uniq:[s:"$1,$2"]} /[,;]/)*
               ln)* ~
  i_accKey:  ~ {$In:[fields c:acc] $Out:accKey} 'AC' /[A-Z]+/ {$Wrt} ~
  i_dbOri:   ~ {$In:[fields c:acc] $Out:dbOri
                 init { $dbOriN={
                         A:1 F:1 V:1 X:1 Y:1 Z:1
                         AA:2 AC:2 AD:2 B:2 G:2 H:2 I:2 J:2 K:2 
                         L:2 M:2 N:2 R:2 S:2 T:2 U:2 W:2 
                         AB:3 C:3 D:3 E:3}
                       $dbName={1:EMBL 2:GenBank 3:DDBJ}
                 }
               } 
               'AC' /[A-Z]+/ {$Wrt:[s:$dbName.$dbOriN.$Ct]} ~
  i_seqLen:  ~ {$In:[fields c:sq] $Out:seqLen}
               'SQ   Sequence' /[0-9]+/ {$Wrt} ~

  # indexing features
  ftWord:    ~ /[^" ,;:()\n.-]+/ ~ #"
  ftSep:     ~ /[ ,;.:()-]+/ ~
  ftKey:     ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               'FT' /[^ ]+/ {$Wrt:[n:$ftN]} ~
  ftQual:    ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               /[^\/]+/ 
               (/\/([a-zA-Z0-9_]+)/ {$Wrt:[s:$1 n:$ftN]} (/=[a-zA-Z0-9_]+/ |
               /="[^"]+"/)? /[^\/]+/)* ~ #"
  chrsNo:    ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               /.+\/chromosome="?/ 
               (/[^\n\" ]+/ {$Uniq:[n:$ftN n:0]} | '\nFT' | ' ')+ ~ #"
  ftSrc:     ~ {$In:[fields c:ft count:ft var:$ftN] $Out}
   (/[^\/]+\/(tissue_type|cell_line|organism|strain|dev_stage|sex|clone_lib)="/ 
                ('\nFT' | ftWord {$Uniq:[n:$ftN]} | ftSep)+ | '/')* ~
  ftDes:     ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               (/[^\/]+\/(product|note|gene)="/ 
                ('\nFT' | /NCBI gi: *[0-9]+/ | 
                 ftWord {$Uniq:[n:$ftN]} | ftSep)+ | '/')* ~
  map:       ~ {$In:[fields c:ft count:ft var:$ftN] $Out}
               /.+\/map="/ (/[^a-zA-Z0-9"]+/|/[a-zA-Z0-9]+/{$Wrt:[n:$ftN]})+ #"
             ~
  pid:       ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               (/db_xref="?PID:([0-9a-zA-Z]+)/ {$Wrt:[n:$ftN s:$1]} |
                /[^\/]+\// )+ ~

  # displaying features
  ftClean:   ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out } 
               'FT' ln {$Wrt} ('FT' ln {$App})* ~
  ftLoc:     ~ {$In:ftClean $Out} /[^ ]+/ /[^\/]+/ {$Wrt} ~
  ft:        ~ {$In:[fields c:ft count:ft var:$ftN select:$subEntryN] $Out}
               /.*/ {$Wrt} ~
  ftId:      ~ {$In:[fields c:id] $Out} 
               /.. *([A-Z0-9]+)/ {$Wrt:[s:"ID   $1\_$subEntryN;  parent: $1"]}~
  h_ftId:    ~ {$In:[ftId t:html]} /.*parent: */ 
               /[A-Z0-9]+/ {$Rep:{$ParStr:emblIdR $Ct $Ct}} ~
  t_ft:      ~ {$In:ftClean $Out} /(<A HREF)?[^ ]+/ {$Wrt:key} 
               /[^\/]+/ t_qual* ~
  t_qual:    ~ /[ \n]*\/([^ \n=]+)/ {$qn=$1 $Uniq:[qual s:$1]} 
               qualval? {$Wrt:[$qn s:$qv]} ~
  qualval:   ~ {pre $qv=""} /=([a-zA-Z0-9_]+)/ {$qv=$1} | 
               /="([^"]+)"/ {$qv=$1} | x{$qv='+'} ~

  # extracting feature sequences"

  ftCleanIter: ~ {$In:[fields c:ft] $Out } 
               'FT' ln {$Wrt} ('FT' ln {$App})* ~
  ftLocat:    ~ {$In:ftClean $Out init {$SdbFunctions}}
               /(<A HREF)?[^ ]+/ /[^\/]+/ {$Wrt} ~
               
  # printing tables
  t_authors: ~ {$In:[fields c:refaut] $Out} 'RA' ln {$Wrt} ('RA' ln {$App})* ~
  t_des:     ~ {$In:[fields c:des] $Out} 'DE' ln {$Wrt} ('DE' ln {$App})* ~ 

  # printing in HTML format
  h_ft:      ~ {$In:[fields c:ft t:html count:ft var:$ftN]} 
               'FT' /[^ ]+/ {$Rep:{$ParStr:emblFeatR $entryName $ftN $Ct}}  
#               /[^\/]+/ 
#               (/\/([a-zA-Z0-9_]+)/ {$Rep:{$ParStr:emblFtQualR $1 $Ct}}
#               (/=[a-zA-Z0-9_]+/ | /="[^"]+"/)? /[^\/]+/)* 
             ~
  h_id:      ~ {$In:[fields c:id t:html]} /../ name {$entryName=$Ct} ~
  h_rx:      ~ {$In:[fields c:rx t:html]}
               /../ 'MEDLINE;' /[0-9]+/ {$Rep:{$ParStr:medlineR $Ct $Ct}} ~
  htmlTag:   ~ /<[^<>]*>/ ~
  h_links:   ~ {$In:[fields c:link t:html] 
                init{$hl={
                       'SWISS-PROT':                    swissR
                       DICTYDB:   dictydbR   GCRDB:     gcrdbR
                       MAIZEDB:   maizedbR   WORMPEP:   wormpepR
                       LISTA:     listaR  
                       PIR:       pirR       YEPD:      yepdR        
                       SGD:        sgdR       
                       STYGENE:   stygeneR     
                       HIV:       hivR         
                       ECOGENE:   ecogeneR   ECO2DBASE: eco2dbaseR   
                       MIM:       mimR       SUBTILIST: subtilistR   
                       FLYBASE:   flybaseR     
                       TRANSFAC:  transfacR  REBASE:    rebaseR
                     } 
                    } 
               }
               (/DR/ dbName {$db=$Ct} ';' 
                accno {$Rep:{$ParStr:$hl.$db $Ct $Ct}} ln)*
             ~
  # other stuff

  word:      ~ /[^" ,;:()\/=\n.-]+/ ~
  sp:        ~ /[ ,;.:()\/=-]+/ ~
  lnCode:    ~ /\n[A-Z][A-Z]/ ~
  ln:        ~ /[^\n]*\n/ ~
  accno:     ~ /[A-Z0-9]+/ ~
  num:       ~ /(<|>)?[0-9?]+/ ~
  name:      ~ /[a-zA-Z0-9_-]+/ ~ 
  dbName:    ~ /[^;]+/ ~ 
}

if:$TestMode {
  $job = $JobNew:[prod:$rules skip:" " fileName:'/data/embl_dna/mam.dat']
  while:$JobHasInput:$job {
    $JobTokens:[$job name:acc print:0] 
    $JobTokens:[$job name:t_ft print:1]
    $JobNext:$job
    #$print:"-------->entry\n"
  }
}



--------------1357101B5F987D624118B159--


From owner-srs@net.bio.net Wed Dec 11 22:00:00 1996
Path: biosci!rutgers!uwm.edu!www.nntp.primenet.com!nntp.primenet.com!usenet.eel.ufl.edu!warwick!lyra.csx.cam.ac.uk!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: srs 5.0 - srscheck
Date: Thu, 12 Dec 1996 14:51:49 +0000
Organization: SEQNET
Lines: 50
Distribution: bionet
Message-ID: <32B01C05.1CFB@dl.ac.uk>
NNTP-Posting-Host: s-ind2.dl.ac.uk
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Hello folks,

I noted a few odd things with srscheck in the new SRS 5.0

If a library is up to date, it still puts a line like
srsbuild PIR -f '' -xdir 'SRSINX:' -odir 'SRSINX:' -env 'unix'
in the srsupdate file, which gives an error message when you
run it.

Sometimes commands for the compression (and merging) of 
up to date databases are inserted. As far as I could find
out this occurs if one or more of its indices contain 0 entries.

The fssp database at our site consists of a directory filled
with symbolic links to the real fssp data, and the "suppos" and
"comp3D" alternative fssp data. It indexes allright, but srscheck
keeps on thinking that there are 0 entries in that directory,
and orders a reindexing since the index contains 1090 entries.

Another thing which causes some problems is that for single entry
databases getz apparently expects entries to be in a file called
"id.ext" ("id" the id of the entry, and "ext" the extension for the
files in this database.) This works nice if you have a your pdb files
named this way (e.g. 1azu.pdb), but at our site we have names like
"pdb1azu.ent". Indexing goes fine, but retrieving the data is
impossible. A similar problem exists with fssp, were a filename
may have an additional character indicating a different chain.



For the curious people - the experimental (and very much incomplete)
SEQNET srs5.0 server can be found at http://www.seqnet.dl.ac.uk/srs5.0
- but don't  expect things to work there yet.....
Until we have all the icarus files sorted out for all the databases
we have on our srs4 server (http://www.seqnet.dl.ac.uk/srs/srsc) we
will not switch to srs5.


Cheers,

Martin
-- 
-----------------------------------------------------------------
| Martin Hilbers        |    E-mail: m.p.hilbers@dl.ac.uk       |
| SEQNET                |    Tel:    +44-1925-603492            |
| Daresbury Laboratory  |    Fax:    +44-1925-603100            |
| Daresbury, Warrington |---------------------------------------|
| Cheshire WA4 4AD      | SEQNET is the UK national EMBNet node |
| United Kingdom        | http://www.dl.ac.uk/SEQNET/home.html  |
-----------------------------------------------------------------

From owner-srs@net.bio.net Thu Dec 12 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!agate!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!warwick!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Tao Jiang <jiangt@pku.edu.cn>
Subject: Re: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32B0B1D7.7C88435F@pku.edu.cn>
Date: Fri, 13 Dec 1996 01:31:03 GMT
To: Peter Rice <pmr@sanger.ac.uk>
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References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de>
		<32AF65E2.36601FB1@pku.edu.cn> <PMR.96Dec12103459@unst.sanger.ac.uk>
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Peter Rice wrote:
 
> The changes worked for me. Memory usage dropped dramatically, at least
> in the early stages (then I went home, and it was finished this morning).
> Maybe something went wrong with the "srsmake srsbuild" step? Or else you
> really have very little memory on your system.
> 
> Our SRS 5.0 server will be available next week.
> 
> I am still busy exploring the icarus files. I expect to be changing the
> indexing methods, and adding new databases, frequently for some time yet.
> --
>  

Well, in fact I have pnly 32M in my system. Then how much
memory is proper for SRS5.0??

regards,

-- 
Tao Jiang            Fax: 86-10-62751982
Network Center       Homepage: http://jiangt.pku.edu.cn/~jiangt/
Peking University    Email: jiangt@pku.edu.cn

From owner-srs@net.bio.net Thu Dec 12 22:00:00 1996
Path: biosci!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: Fri, 13 Dec 1996 10:03:08 +0000
Organization: SEQNET
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Message-ID: <32B129DB.41C6@dl.ac.uk>
References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de>
			<32AF65E2.36601FB1@pku.edu.cn> <PMR.96Dec12103459@unst.sanger.ac.uk> <32B0B1D7.7C88435F@pku.edu.cn>
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Tao Jiang wrote:
> 

> 
> Well, in fact I have pnly 32M in my system. Then how much
> memory is proper for SRS5.0??
> 
> regards,
> 

The DEC alpha on which I have our SRS server also has only 32 M,
(and 155 M swapspace), and indexing the embl phage section takes
only a few minutes. (although it is considerable slower than srs4)

-- 
-----------------------------------------------------------------
| Martin Hilbers        |    E-mail: m.p.hilbers@dl.ac.uk       |
| SEQNET                |    Tel:    +44-1925-603492            |
| Daresbury Laboratory  |    Fax:    +44-1925-603100            |
| Daresbury, Warrington |---------------------------------------|
| Cheshire WA4 4AD      | SEQNET is the UK national EMBNet node |
| United Kingdom        | http://www.dl.ac.uk/SEQNET/home.html  |
-----------------------------------------------------------------

From owner-srs@net.bio.net Sun Dec 15 22:00:00 1996
Path: biosci!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: Mon, 16 Dec 1996 13:28:33 +0000
Organization: SEQNET
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Message-ID: <32B54E81.41C6@dl.ac.uk>
References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de>
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Thure wrote:
> 

> I found the bug, in fact there were two:
> 
> 1) edit file src/icarus.c
> 
> after line 670 you find
> 
>     if (!IcaCursorIsInput (job->inCursor, job->cursor)) {
> /*      CursorDelete (&job->cursor); */
>       job->cursor = NULL;
> 
>     }
> 
> remove the comments and rebuild srsbuild:
> 
> srsmake srsbuild
> 
> 2) edit icarus/db/embl.is
> 
> around line 55 you find
> 
>   seq:       ~ (/.*2BIT *Len:/ /[0-9]+/ {$len=$Ct} ln ln
>                {$s=$SeqGet2Bit:[$s file:$File len:$len]} ('>>>>'{$Not} ln)*|
>                /.*ASCII/ ln ln ('>>>>' {$Not} /.*/ {$SeqApp:[$s
> s:$Ct]})+) ~
> 
> change '$s=$SeqGet2Bit' to '$SeqGet2Bit'
> 
> regards
> thure


Despite the changes, I seem to have a memory problem. I tried to
index the new EMBL release this weekend, and it crashed with this
message:

...no. 720600, MJU67483
SRSDB:embl.is:72: error: insufficient memory - error during malloc,
could not allocate "sequence"

I retried, but now tracked memory usage during srsbuild, and it
appears that after writing a subindex (*_1.inx etc), memory usage
hardly decreases, and continues to increase when srsbuild works
further through the database. I would expect that a significant 
amount of memory would be freed after writing an index file, or
that memory usage almost stops growing after writing the first one.

Is it possible there is a problem with freeing/reallocating memory
after a subindexfile has been written ?

This was with gcg formatted embl. I also made changes to the
embl.i and embl.is files, but I don't really think that causes the
problem (Ofcourse I might be completely wrong with that :-))

Cheers,

Martin

-- 
-----------------------------------------------------------------
| Martin Hilbers        |    E-mail: m.p.hilbers@dl.ac.uk       |
| SEQNET                |    Tel:    +44-1925-603492            |
| Daresbury Laboratory  |    Fax:    +44-1925-603100            |
| Daresbury, Warrington |---------------------------------------|
| Cheshire WA4 4AD      | SEQNET is the UK national EMBNet node |
| United Kingdom        | http://www.dl.ac.uk/SEQNET/home.html  |
-----------------------------------------------------------------

From owner-srs@net.bio.net Mon Dec 16 22:00:00 1996
Newsgroups: bionet.software.srs
Path: biosci!rutgers!uwm.edu!news-peer.gsl.net!news.gsl.net!howland.erols.net!agate!nntpfeed.doc.ic.ac.uk!sunsite.doc.ic.ac.uk!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!news
From: Tao Jiang <jiangt@pku.edu.cn>
Subject: Re: question about SRS5.0
Sender: news@ebi.ac.uk (usenet news)
Message-ID: <32B5FAE8.4E059D36@pku.edu.cn>
Date: Tue, 17 Dec 1996 01:44:08 GMT
To: Thure <etzold@embl-heidelberg.de>
Content-Transfer-Encoding: 7bit
Content-Type: text/plain; charset=us-ascii
References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEA3C2.41C6@embl-heidelberg.de>
Mime-Version: 1.0
X-Mailer: Mozilla 3.01Gold (X11; I; Linux 2.0.0 i586)
Organization: Network Center
Lines: 25

Thure wrote:
 
 
> then you must change the file names at the beginning of the file
> 
> $file:pro
> 
> will have to change to
> 
> $file:em_pro
> 

Is $file:pro means the gcg format while $file:em_pro
means the original format?
In my CD the file name is pro with original format,
and should I need to change its name to em_pro after I
copy it to hard disk?
 
> regards
> thure

-- 
Tao Jiang            Fax: 86-10-62751982
Network Center       Homepage: http://jiangt.pku.edu.cn/~jiangt/
Peking University    Email: jiangt@pku.edu.cn

From owner-srs@net.bio.net Tue Dec 17 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!nntp.uio.no!news.apfel.de!fu-berlin.de!news-ber1.dfn.de!news-ham1.dfn.de!news-han1.dfn.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: srs5.01
Date: Wed, 18 Dec 1996 23:56:03 +0100
Organization: EMBL
Lines: 29
Distribution: world
Message-ID: <32B87683.167E@embl-heidelberg.de>
NNTP-Posting-Host: kappa.embl-heidelberg.de
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0 (X11; I; OSF1 V2.0 alpha)

Dear folks,

this is to announce version 5.01 of SRS. The main difference is the
fix of the memory fragmentation problem with srsbuild and EMBL indices.

A few minor things got fixed too:

o "download page" is now functional.
o swissprot and embl entries have no longer duplicated SQ lines
o added the Citation index for both Swissprot and EMBL
o the install procedure produces by default optimized code (O2) 

the distribution is available as

ftp://www.embl-heidelberg.de/pub/databases/trembl/srs5_01.tar.gz


regards
Thure Etzold
Jonny Weare



-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Tue Dec 17 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!voskovec.radio.cz!btnet-feed2!unlisys!cs.tu-berlin.de!zrz.TU-Berlin.DE!news-ber1.dfn.de!news-lei1.dfn.de!news-nue1.dfn.de!news-mue1.dfn.de!news-stu1.dfn.de!news-kar1.dfn.de!news-koe1.dfn.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: Wed, 18 Dec 1996 11:16:39 +0100
Organization: EMBL
Lines: 45
Distribution: world
Message-ID: <32B7C487.41C6@embl-heidelberg.de>
References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de> <32B54E81.41C6@dl.ac.uk>
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To: Martin Hilbers <mph@dl.ac.uk>
CC: Tao Jiang <jiangt@pku.edu.cn>

Martin Hilbers wrote:
> 
> Despite the changes, I seem to have a memory problem. I tried to
> index the new EMBL release this weekend, and it crashed with this
> message:
> 
> ...no. 720600, MJU67483
> SRSDB:embl.is:72: error: insufficient memory - error during malloc,
> could not allocate "sequence"
> 

sorry for the long silence - I was sick for a couple of days. I found
the problem with index building for EMBL. It is not caused by a memory
leak but by memory fragmentation. Building the index chunks iteratively
requires large chunks of memory to be freed and allocated at each 
run and for some reason the program gets new memory from the system 
instead of
reclaiming freed blocks. This behaviour is much more pronounced on
irix than osf1. srsbuild does now the memory management for these
large chunks itself which seems to solve the problem. I managed to 
build EMBL with less than 50 mbyte virtual memory

Tao, since you have only 32mb you should really try to upgrade your
machine but in the meantime you could try to set the partition size
to 60000

EMBL_DB:$library:[EMBL group:@SEQUENCE_LIBS partSize:60000
  ...

We hope to create a new version with these changes by the end of the
day which will be announced.

regards
Thure


   


-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Wed Dec 18 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!nntp.uio.no!news.apfel.de!fu-berlin.de!news-ber1.dfn.de!news-ham1.dfn.de!news-han1.dfn.de!news-koe1.dfn.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Johnathon Weare <weare@dove.embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: Re: srs5.01
Date: 19 Dec 1996 18:39:19 +0100
Organization: EMBL Heidelberg
Lines: 11
Distribution: world
Message-ID: <w17916ul9h4.fsf@dove.embl-heidelberg.de>
References: <32B87683.167E@embl-heidelberg.de>
NNTP-Posting-Host: dove.embl-heidelberg.de
X-Newsreader: Gnus v5.3/Emacs 19.32


Instead of

ftp://www.embl-heidelberg.de/pub/databases/trembl/srs5_01.tar.gz

read

ftp://ftp.embl-heidelberg.de/pub/databases/trembl/srs5_01.tar.gz


Johnny

From owner-srs@net.bio.net Wed Dec 18 22:00:00 1996
Path: biosci!britbio.co.uk!dudgeon
From: dudgeon@britbio.co.uk (Tim Dudgeon)
Newsgroups: bionet.software.srs
Subject: hssp swissprot links
Date: 19 Dec 1996 09:08:55 -0800
Organization: British Biotech
Lines: 20
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <32B96831.6231@britbio.co.uk>
NNTP-Posting-Host: net.bio.net

Dear SRS-folk,

I'm having problems building the hssp-swissprot link with SRS4.08. When
I do:

srsbuild HSSP -l -xdir 'SRSINX:' -odir 'SRSINX:'  -env 'unix'

I (eventually) get:

e__settoosmall, set has not enough space for IDs
attempt to copy 300001 IDs where only for 300000 is space

Looks like I need to reparameterise something. Any suggestions?

Tim

-- 
Dr. Tim Dudgeon                           Phone: 01865 748747
British Biotech Pharmaceuticals Ltd.      FAX:   01865 717598
Watlington Road, Oxford, OX4 5LY, UK      email: dudgeon@britbio.co.uk

From owner-srs@net.bio.net Fri Dec 20 22:00:00 1996
Path: biosci!biosci!not-for-mail
From: malik@uranus.ebi.ac.uk (Ansar Malik)
Newsgroups: bionet.immunology,bionet.molbio.embldatabank,bionet.software.srs
Subject: ANNOUNCEMENT: Immunogenetics IMGT database - update
Date: 21 Dec 1996 13:45:31 -0800
Organization: European Bioinformatics Institute (EMBL) - UK
Lines: 62
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <E2pvyr.Cr1@ebi.ac.uk>
Reply-To: malik@uranus.ebi.ac.uk (Ansar Malik)
NNTP-Posting-Host: net.bio.net
Keywords: database, immunogenetics, immunoglobulin, T cell receptor cell,sequences annotation, DNA sequence
Xref: biosci bionet.immunology:10503 bionet.molbio.embldatabank:738 bionet.software.srs:383



IMMUNOGENETICS IMGT DATABASE
===================================

Professor Marie-Paule LEFRANC
Laboratoire d'ImmunoGenetique Moleculaire, LIGM
UMR CNRS 9942, Institut de Genetique Moleculaire
BP 5051, 1919 route de Mende, 34033 MONTPELLIER Cedex 1
FRANCE
Telephone: (33) 67 61 36 34
FAX      : (33) 67 04 02 31/67 04 02 45
e-mail   : lefranc@ligm.crbm.cnrs-mop.fr

INTRODUCTION
============

The ImMunoGeneTics database, IMGT, is an integrated specialised database
containing nucleotide sequence information of genes important in the function
of the immune system. It collects and annotates sequences belonging to the
immunoglobulin superfamily which are involved in immune recognition, these are
the B cell antigen receptor (Immunoglobulin or Ig), the T cell antigen receptor
(TCR) (LIGM-database) and the class I and class II molecules of the 
Human Leucocyte Antigens (HLA) system (HLA-database).

IMGT/LIGM DATABASE  
==================
An integrated immumogenetics database (IMGT/LIGM) specialising in Ig and TcR is
under development through collaboration between LIGM, IFG and EMBL oustation
EBI. This database consists of the Ig and TcR sequence entries.
Collaborators:
  
Release 96.11 contains 7937 fully annotated sequence entries.
 
LIGM Montpellier :Marie-Paule Lefranc (coordinator)
                  Veronique Giudicelli,Denys Chaume
EMBL-EBI         :Ansar Malik
IFG              :Werner Mueller

ACCESS/DATA DISTRIBUTION
========================

SRS server:     http://www.ebi/srs/srsc

NOTE: Selecting this option will bring you to the SRS qerry interface page, 
where you have to select "search Sequence Libraries" 

WWW server:     http://www.ebi.ac.uk/imgt/
FTP server:     ftp.ebi.ac.uk/pub/databases/imgt
E_MAIL server:  email netserv@ebi.ac.uk  -- send "help IMGT" in the mail body.

This database is available on CD-ROM as an acompanying database
to the EMBL Nucleotide Sequence Database at nominal cost.

=======================================================================
Ansar Malik Ph.D                        | Email:Malik@ebi.ac.uk
EBI - European Bioinformatics Institute | URL:  http://www.ebi.ac.uk
Hinxton Hall, Hinxton                   | Tel:  +44 (1223) 494417
Cambridge CB10 1RQ, UK                  | Fax:  +44 (1223) 494968
========================================================================



From owner-srs@net.bio.net Mon Dec 23 22:00:00 1996
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!su-news-hub1.bbnplanet.com!arclight.uoregon.edu!news.ibm.net.il!news.biu.ac.il!news.tau.ac.il!usenet
From: yoav_ab@netvision.net.il (yoav abrahami)
Newsgroups: bionet.software.srs
Subject: looking for beaker
Date: Tue, 24 Dec 1996 18:33:33 GMT
Organization: Tel-Aviv University Computation Center
Lines: 8
Message-ID: <32c021e2.13313563@news.tau.ac.il>
NNTP-Posting-Host: slip-303.tau.ac.il
X-Newsreader: Forte Free Agent 1.1/32.230

Hello there!
  Maybe someone has a version of the sottware "Beaker" for PC?( not
for mac!!!)
 I will be greatfull if someone can send me a copy or even information
on a ftp site i can download it from. 
 my e-mail is: yoav_ab@netvision.net.il

                                          thanx, yoav. (israel)

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!news.artemis.com!uunet!in1.uu.net!206.229.87.25!news.sprintlink.net!news-peer.sprintlink.net!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!newshost.lanl.gov!biosci!rutgers!iag.net!www.nntp.primenet.com!nntp.primenet.com!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!lhc.nlm.nih.gov!biosci!rutgers!iag.net!www.nntp.primenet.com!nntp.primenet.com!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!agate!howland.erols.net!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!rutgers!iag.net!www.nntp.primenet.com!nntp.primenet.com!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
Lines: 19
Message-ID: <32C3A3F3.642C@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4d)

Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!rutgers!cnn.Princeton.EDU!udel-eecis!gatech!news.sprintlink.net!news-peer.sprintlink.net!voskovec.radio.cz!btnet-feed2!unlisys!cs.tu-berlin.de!zrz.TU-Berlin.DE!news-ber1.dfn.de!news-lei1.dfn.de!news-nue1.dfn.de!news-mue1.dfn.de!news-stu1.dfn.de!news-kar1.dfn.de!news-koe1.dfn.de!news.dfn.de!news.embl-heidelberg.de!usenet
From: Thure Etzold <etzold@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: Re: question about SRS5.0
Date: Wed, 18 Dec 1996 11:16:39 +0100
Organization: EMBL
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References: <32ACBDA7.57D9066B@pku.edu.cn> <32AEC9DA.2781@embl-heidelberg.de> <32B54E81.41C6@dl.ac.uk>
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To: Martin Hilbers <mph@dl.ac.uk>
CC: Tao Jiang <jiangt@pku.edu.cn>

Martin Hilbers wrote:
> 
> Despite the changes, I seem to have a memory problem. I tried to
> index the new EMBL release this weekend, and it crashed with this
> message:
> 
> ...no. 720600, MJU67483
> SRSDB:embl.is:72: error: insufficient memory - error during malloc,
> could not allocate "sequence"
> 

sorry for the long silence - I was sick for a couple of days. I found
the problem with index building for EMBL. It is not caused by a memory
leak but by memory fragmentation. Building the index chunks iteratively
requires large chunks of memory to be freed and allocated at each 
run and for some reason the program gets new memory from the system 
instead of
reclaiming freed blocks. This behaviour is much more pronounced on
irix than osf1. srsbuild does now the memory management for these
large chunks itself which seems to solve the problem. I managed to 
build EMBL with less than 50 mbyte virtual memory

Tao, since you have only 32mb you should really try to upgrade your
machine but in the meantime you could try to set the partition size
to 60000

EMBL_DB:$library:[EMBL group:@SEQUENCE_LIBS partSize:60000
  ...

We hope to create a new version with these changes by the end of the
day which will be announced.

regards
Thure


   


-- 
===============================================================================
Thure Etzold                                   | EMBL
E-mail: etzold@embl-heidelberg.de              | Postfach 10.2209
Tel: (49) 6221 387529                          | 69012 Heidelberg
Fax: (49) 6221 387517                          | Germany

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!bloom-beacon.mit.edu!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!su-news-hub1.bbnplanet.com!arclight.uoregon.edu!news.ibm.net.il!news.biu.ac.il!news.tau.ac.il!usenet
From: yoav_ab@netvision.net.il (yoav abrahami)
Newsgroups: bionet.software.srs
Subject: looking for beaker
Date: Tue, 24 Dec 1996 18:33:33 GMT
Organization: Tel-Aviv University Computation Center
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Hello there!
  Maybe someone has a version of the sottware "Beaker" for PC?( not
for mac!!!)
 I will be greatfull if someone can send me a copy or even information
on a ftp site i can download it from. 
 my e-mail is: yoav_ab@netvision.net.il

                                          thanx, yoav. (israel)

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!CS.Arizona.EDU!news.Arizona.EDU!uunet!in1.uu.net!206.229.87.25!news.sprintlink.net!news-peer.sprintlink.net!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
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Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Thu Dec 26 22:00:00 1996
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed1.bbnplanet.com!news.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.sprintlink.net!news-peer.sprintlink.net!nntp.coast.net!oleane!pasteur.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: swissprot and embl under SRS5_01
Date: Fri, 27 Dec 1996 11:24:51 +0100
Organization: INFOBIOGEN
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Hello all,

I find some problems in srs5_01 with embl and swissprot
I have message like : 
	unknown object
 	input file type "seq" does not exist

It was the same error message as in version srs5_0
The changes were made in icarus.c and embl.is

Thanks for your help in advance
-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Fri Dec 27 22:00:00 1996
Path: biosci!rutgers!igor.rutgers.edu!newsserver.jvnc.net!news.merck.com!cam-news-feed1.bbnplanet.com!delphi.com!news-feed.iguide.com!news.uoregon.edu!arclight.uoregon.edu!feed1.news.erols.com!howland.erols.net!usc!news.cerf.net!news1.ni.net!news
From: polo@haha.com (polo)
Newsgroups: bionet.software.srs
Subject: ***** http://206.103.186.160 *****
Date: Wed, 18 Dec 1996 06:04:11 GMT
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From owner-srs@net.bio.net Sun Dec 29 22:00:00 1996
Path: biosci!rutgers!iag.net!news.sgi.com!esiee.fr!jussieu.fr!oleane!pasteur.fr!univ-lyon1.fr!news.imag.fr!ciril.fr!univ-angers.fr!univ-rennes1.fr!cict.fr!news
From: Lionel Mourey <mourey@ecstasy.cemes.fr>
Newsgroups: bionet.software.srs
Subject: Professor position at Toulouse University
Date: Mon, 30 Dec 1996 16:12:37 +0100
Organization: CNRS-IPBS
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-----------------------------------------
PROFESSOR POSITION AT TOULOUSE UNIVERSITY
-----------------------------------------

A Professor position is opened at Toulouse University in 1997.

The area of scientific expertise is Biocomputing.  Teaching will start
in October 1997.

Research will  be held  at  the  CNRS Institute of  Pharmacology   and
Structural    Biology (IPBS)   in  the  areas    of protein structure,
protein-protein  and protein-ligand interactions with special emphasis
in sequence and structure   similariry searching, human  and microbial
genome analysis, computer sciences.

Completed applications must be received by January 17, 1997 at:

UPS, Service du personnel enseignant
118 route de Narbonne
31058 - TOULOUSE   FRANCE

Additional informations can be obtained from:

        Pr. Jean CROS, IPBS,            Tel: 33 05 61 17 59 18
                                        Fax: 33 05 61 17 59 94
                                        email: cros@ipbs.fr

        Dr. J. P. Samama, IPBS          Tel: 33 05 62 25 78 08
                                        Fax: 33 05 62 25 79 60
                                        email: samama@ipbs.fr
                                            or samama@ecstasy.cemes.fr

        Dr. G. Puzo, IPBS               Tel: 33 05 61 33 59 10
                                        Fax: 33 05 61 33 58 86
                                        email: germain@lptf.biotoul.fr

        Institut de Pharmacologie et de Biologie Structurale
        CNRS, UPR 9062
        205 Route de Narbonne
        31 077 - Toulouse, France

-------------------------------------------------------------------
Lionel MOUREY		
Groupe de Cristallographie Biologique de l'IPBS
CEMES-LOE/CNRS			
29 rue Jeanne Marvig 	      Tel (33 or 0) 5 62 25 79 63 
BP 4347			      Fax (33 or 0) 5 62 25 79 60   
31055 TOULOUSE CEDEX	      e-mail   mourey@ipbs.fr 
France
-------------------------------------------------------------------

