From owner-srs@net.bio.net Mon Aug 04 23:00:00 1997
Message-ID: <33E70DCF.34E8@faw.uni-ulm.de>
Date: Tue, 05 Aug 1997 13:26:07 +0200
From: Markus Kieninger <kieninge@faw.uni-ulm.de>
X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.5 sun4c)
MIME-Version: 1.0
Newsgroups: bionet.software.srs
CC: kieninge
Subject: Problems with large sequences and applications in srs5.0.5
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
NNTP-Posting-Host: merlin.faw.uni-ulm.de
Lines: 16
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!194.162.162.196!newsfeed.nacamar.de!blackbush.xlink.net!rz.uni-karlsruhe.de\!news.uni-ulm.de!merlin.faw.uni-ulm.de

Hallo ! 

Each time I launch an application from SRS (e.g. TSWP) with a large
sequence (e.g. HSLBRCA1 from EMBL-HUM) the CGI-Script stops in the
middle of the following page. I tested it on my local copy of SRS and on
the EMBL-Server with the same result. 
There are no problems if i launch an application with a smaller
sequences (e.g. YTY1A1 from EMBL-FUN). 
Could this be a range problem in SRS ?

Markus Kieninger

------------------------------------------------------
Markus Kieninger    Tel.:   0731/501-8758
FAW, Ulm            E-Mail: kieninge@faw.uni-ulm.de
------------------------------------------------------

From owner-srs@net.bio.net Wed Aug 06 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!baron.netcom.net.uk!netcom.net.uk!news-peer!btnet!nntp.news.xara.net!xara.net!nntp2.news.xara.net!xara.net!server5.netnews.ja.net!server3.netnews.ja.net!server4.netnews.ja.net!server2.netnews.ja.net!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: etzold <etzold@ebi.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Problems with large sequences and applications in srs5.0.5
Date: Thu, 07 Aug 1997 14:25:20 +0100
Organization: EMBL-EBI
Lines: 16
Message-ID: <33E9CCC0.6F0B6D45@ebi.ac.uk>
References: <33E70DCF.34E8@faw.uni-ulm.de>
NNTP-Posting-Host: idefix.ebi.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.01 [en] (Win95; I)
To: Markus Kieninger <kieninge@faw.uni-ulm.de>
X-Priority: 3 (Normal)

Markus Kieninger wrote:
> 
> Hallo !
> 
> Each time I launch an application from SRS (e.g. TSWP) with a large
> sequence (e.g. HSLBRCA1 from EMBL-HUM) the CGI-Script stops in the
> middle of the following page. I tested it on my local copy of SRS and on
> the EMBL-Server with the same result.

oops ...we don't even have an application here for DNA sequences so
it has never been tested for large sequences. We are working on
version 5.1 where the entire module dealing with sequences has been
rewritten and i hope that the error will not occur anymore

regards
thure

From owner-srs@net.bio.net Fri Aug 08 23:00:00 1997
Path: biosci!agate!newsfeed.kornet.nm.kr!howland.erols.net!vixen.cso.uiuc.edu!news.indiana.edu!not-for-mail
From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software.srs
Subject: 256 limit on number of library ids too small?
Date: 8 Aug 1997 16:02:45 GMT
Organization: Biology, Indiana University - Bloomington
Lines: 31
Message-ID: <5sffv5$hrh$1@dismay.ucs.indiana.edu>
NNTP-Posting-Host: chipmunk.bio.indiana.edu

We are trying to add several flybase data sections to SRS
in a way that is compatible with use with other SRS databases.
It looks like the current srsdb.i has a limit of 256 library
ids.  Numbers 1 - 140 are mostly taken by prior databanks,
numbers 200 - 205 and 230-232 are taken.

Questions:  
  -- can the 256 number limit be expanded for the standard SRS
 to a short int at least?

  -- could we reserve and use for now lib ids 180 - 199 for flybase data
  sections?


As an aside, we hope to make available icarus files for all FlyBase
drosophila genome data soon, for anyone who wants to incorporate any of this
in a standard SRS server.  Because the flybase portable server we provide
includes a more integrated service for Drosophila data, we recommend
it over the standard SRS view of fly data.  But if
you have an SRS server, and want to add Drosophila data w/o an
added server, please do use the icarus files we have prepared.
You can I think install both and share indices between SRS standard
and portable flybase servers (I'm off to test that).

See http://flybase.bio.indiana.edu
for current srs usage integrated in flybase service, and
http://iubio.bio.indiana.edu/srs/ for preliminary uses in standard SRS.

-- Don
--
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-srs@net.bio.net Sun Aug 10 23:00:00 1997
Path: biosci!bloom-beacon.mit.edu!howland.erols.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!europa.clark.net!158.152.1.94!dispatch.news.demon.net!demon!delos.dra.hmg.gb!server1.netnews.ja.net!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: etzold <etzold@ebi.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: 256 limit on number of library ids too small?
Date: Mon, 11 Aug 1997 14:06:02 +0100
Organization: EMBL-EBI
Message-ID: <33EF0E3A.125F0C8A@ebi.ac.uk>
References: <5sffv5$hrh$1@dismay.ucs.indiana.edu>
NNTP-Posting-Host: idefix.ebi.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.01 [en] (Win95; I)
To: Don Gilbert <gilbertd@bio.indiana.edu>
X-Priority: 3 (Normal)
Lines: 8

yes, we plan to extend the library-ID to a short which would give
us a max of 65000 different databanks. Can't say when this will be
available
but probably within the next months


regards
thure

From owner-srs@net.bio.net Sun Aug 10 23:00:00 1997
Path: biosci!daresbury!uninett.no!news.uni-c.dk!eagle.novo.dk!not-for-mail
From: Peter Gildsig Jansen <pcgj@novo.dk>
Newsgroups: bionet.software.srs
Subject: SRS 5.0.5 on LINUX
Date: Mon, 11 Aug 1997 14:22:35 +0200
Organization: Novo Nordisk
Lines: 40
Message-ID: <33EF040B.31DF@novo.dk>
NNTP-Posting-Host: mozart.novo.dk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0Gold (X11; I; IRIX 5.3 IP22)

Hi SRS people

Have anybody here compiled SRS 5.0.5 successfully on
linux (gcc version 2.7.2)?

I get some warnings like:

sdlnew.c:454: warning: initialization makes integer from pointer without
a cast

error.c: In function `ErrNewStack':
error.c:45: warning: passing arg 2 of `memset' makes integer from
pointer without a cast
error.c: In function `ErrPrint':
error.c:125: warning: passing arg 2 of `memset' makes integer from
pointer without a cast
error.c:126: warning: passing arg 2 of `memset' makes integer from
pointer without a cast

In file included from library.c:60:
appl.h:4: warning: `struct LIBoDataType' declared inside parameter list
appl.h:4: warning: its scope is only this definition or declaration,
appl.h:4: warning: which is probably not what you want.
library.c:130: warning: initialization makes integer from pointer
without a cast


... and then the srssection program (actually the nodd program) 
makes a core dump.

Any suggestions?

thanks /// peter

-- 
-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
Peter Gildsig Jansen                       Scientific Computing
pcgj@novo.dk                                       Novo Nordisk
http://biobase.dk/~jansen                               Denmark
-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-

From owner-srs@net.bio.net Sun Aug 10 23:00:00 1997
Path: biosci!CIGB.EDU.CU!Ricardo.Bringas
From: Ricardo.Bringas@CIGB.EDU.CU ("RICARDO BRINGAS")
Newsgroups: bionet.software.srs
Subject: Re: SRS 5.0.5 on LINUX
Date: 11 Aug 1997 12:38:41 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 39
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <745D3500E9@serverdos.cigb.edu.cu>
NNTP-Posting-Host: net.bio.net

> Have anybody here compiled SRS 5.0.5 successfully on 
> linux (gcc version 2.7.2)?

I tried linux kernel 2.0.27, but I had a lot of problems. I tried
then an older linux kernel 1.2.13 and after fixing a few small bugs
it is running properly.
 
> I get some warnings like:
> 
> sdlnew.c:454: warning: initialization makes integer from pointer without
> a cast
> 
> error.c: In function `ErrNewStack':
> error.c:45: warning: passing arg 2 of `memset' makes integer from
> pointer without a cast
> error.c: In function `ErrPrint':
> error.c:125: warning: passing arg 2 of `memset' makes integer from
> pointer without a cast
> error.c:126: warning: passing arg 2 of `memset' makes integer from
> pointer without a cast
> In file included from library.c:60:
> appl.h:4: warning: `struct LIBoDataType' declared inside parameter list
> appl.h:4: warning: its scope is only this definition or declaration,
> appl.h:4: warning: which is probably not what you want.
> library.c:130: warning: initialization makes integer from pointer
> without a cast
I got several of these warning messages in both kernels, do not care ...

> ... and then the srssection program (actually the nodd program) 
> makes a core dump.
>        
> Any suggestions?

A similar error was posted some time ago.

Ricardo Bringas
Center for Genetic Engineering & Biotechnology
PO Box 6162, Havana, Cuba
E-mail : Ricardo.Bringas@cigb.edu.cu

From owner-srs@net.bio.net Mon Aug 11 23:00:00 1997
Path: biosci!agate!newsfeed.kornet.nm.kr!howland.erols.net!vixen.cso.uiuc.edu!news.indiana.edu!not-for-mail
From: gilbertd@bio.indiana.edu (Don Gilbert)
Newsgroups: bionet.software.srs
Subject: Re: Problems in  srsdb.i
Date: 12 Aug 1997 23:24:22 GMT
Organization: Biology, Indiana University - Bloomington
Lines: 7
Message-ID: <5sqrb6$gk3$1@dismay.ucs.indiana.edu>
References: <5sp6cn$t57@lion.embl-heidelberg.de>
NNTP-Posting-Host: chipmunk.bio.indiana.edu

after changing a lib-id one needs to reindex the
affected libraries. could that be the the problem?
i ran into similar errors when i failed to reindex.

- don
--
-- d.gilbert--biocomputing--indiana u--bloomington--gilbertd@bio.indiana.edu

From owner-srs@net.bio.net Mon Aug 11 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!dispatch.news.demon.net!demon!delos.dra.hmg.gb!server1.netnews.ja.net!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: etzold <etzold@ebi.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Problems in  srsdb.i
Date: Tue, 12 Aug 1997 19:39:03 +0100
Organization: EMBL-EBI
Message-ID: <33F0ADC7.EF2311A4@ebi.ac.uk>
References: <5sp6cn$t57@lion.embl-heidelberg.de>
NNTP-Posting-Host: etzold_p.ebi.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.01 [en] (Win95; I)
To: Ramu Chenna <chenna@embl-heidelberg.de>
X-Priority: 3 (Normal)
Lines: 15

Ramu Chenna wrote:
> 
> Hello All
> 
> The other day I wanted to change the libid for PIR in srsdb.i. I changed it
> from 8 to 13 and did a srssection. srssection did not compalin anything
> but when i tried
> 

changing the libid is a serious change and requires a full reindex of
the
databank. (all entry-id's contain the library id!)

regards
thure

From owner-srs@net.bio.net Mon Aug 11 23:00:00 1997
Path: biosci!daresbury!uninett.no!news-feed.inet.tele.dk!newsfeed.nacamar.de!news-kar1.dfn.de!news.embl-heidelberg.de!usenet
From: Ramu Chenna <chenna@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: Problems in  srsdb.i
Date: 12 Aug 1997 08:20:39 GMT
Organization: EMBL, Heidelberg, Germany
Lines: 28
Distribution: world
Message-ID: <5sp6cn$t57@lion.embl-heidelberg.de>
NNTP-Posting-Host: shag.embl-heidelberg.de
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.12IS (X11; I; IRIX 5.3 IP22)
X-URL: news:bionet.software.srs?ALL

Hello All

The other day I wanted to change the libid for PIR in srsdb.i. I changed it 
from 8 to 13 and did a srssection. srssection did not compalin anything
but when i tried  

getz '[pir-id:S33532]'  I got

SWISSNEW:

and with 

getz '[pir-id:S33532]' -e 

Segmentation fault

Can somebody help me out.  

Ramu

-- 
_______________________________________________________________
Chenna Ramu; EMBL; Postfach 10.2209; 69012 Heidelberg; Germany.
Email: chenna@embl-heidelberg.de
   Url: http://www.embl-heidelberg.de/~chenna/
   Tel: (49) 6221 387530 (Off) ; Fax: (49) 6221 387517
______


From owner-srs@net.bio.net Tue Aug 12 23:00:00 1997
Path: biosci!agate!newsfeed.kornet.nm.kr!xfer.kren.nm.kr!newsfeed.dacom.co.kr!newsfeed.direct.ca!newsfeed.nacamar.de!news-kar1.dfn.de!news.embl-heidelberg.de!usenet
From: Ramu Chenna <chenna@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: wgetz: include in list (Bug)
Date: 13 Aug 1997 09:14:27 GMT
Organization: EMBL, Heidelberg, Germany
Lines: 16
Distribution: world
Message-ID: <5srttj$j6n@lion.embl-heidelberg.de>
NNTP-Posting-Host: shag.embl-heidelberg.de
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.12IS (X11; I; IRIX 5.3 IP22)
X-URL: news:bionet.software.srs?ALL

Hi 

In the query form page, few fields under "include in list" were 
checked. In the result page all the checked were shown correctly.
But the next chunk shows nothing but the last list checked. Certainly a bug.


Ramu
-- 
_______________________________________________________________
Chenna Ramu; EMBL; Postfach 10.2209; 69012 Heidelberg; Germany.
Email: chenna@embl-heidelberg.de
   Url: http://www.embl-heidelberg.de/~chenna/
   Tel: (49) 6221 387530 (Off) ; Fax: (49) 6221 387517
______


From owner-srs@net.bio.net Tue Aug 12 23:00:00 1997
Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: etzold <etzold@ebi.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: wgetz: include in list (Bug)
Date: Wed, 13 Aug 1997 12:08:48 +0100
Organization: EMBL-EBI
Lines: 20
Message-ID: <33F195C0.C82B9235@ebi.ac.uk>
References: <5srttj$j6n@lion.embl-heidelberg.de>
NNTP-Posting-Host: idefix.ebi.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.01 [en] (Win95; I)
To: Ramu Chenna <chenna@embl-heidelberg.de>
X-Priority: 3 (Normal)

Ramu Chenna wrote:
> 
> Hi
> 
> In the query form page, few fields under "include in list" were
> checked. In the result page all the checked were shown correctly.
> But the next chunk shows nothing but the last list checked. Certainly a bug.
> 

yes that is a bug. In srs5.1 this will be fixed. Selection of
fields will generate a 'view' for the list of databanks that was 
queried. and that view will stay for the entire session

...as you have noticed the release of srs5.1 has been delayed. we
are suffering from 'featuritis' but at least we stopped adding
more things that should be in it ...so end of august is the new
prediction

regards
thure

From owner-srs@net.bio.net Thu Aug 14 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!infeed2.internetmci.com!newsfeed.internetmci.com!192.220.251.22!netnews.nwnet.net!news-hub.interserv.net!news.interserv.com!email-now1.com
From: "SPECIAL !!!" special@email-now1.com
Newsgroups: bionet.software.srs
Subject: COMPUTER  HARDWARE / SOFTWARE
Date: Fri, 15 Aug 1997 01:40:23 -0700
Organization: HIJK
Lines: 6
Message-ID: <150897014023@email-now1.com>
NNTP-Posting-Host: hd66-181.hil.compuserve.com

                <<<COMPUTER  HARDWARE / SOFTWARE>>>

                                       UP TO 70 % OFF  !!!

                          http://members.aol.com/Auction1st
<><=>>><==<<>><=<>>>

From owner-srs@net.bio.net Mon Aug 18 23:00:00 1997
Message-ID: <33F9A8D0.2731@faw.uni-ulm.de>
Date: Tue, 19 Aug 1997 16:08:16 +0200
From: Markus Kieninger <kieninge@faw.uni-ulm.de>
X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.5 sun4c)
MIME-Version: 1.0
Newsgroups: bionet.software.srs
CC: kieninge
Subject: Question about QueryResult-Page
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
NNTP-Posting-Host: merlin.faw.uni-ulm.de
Lines: 28
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!infeed1.internetmci.com!newsfeed.internetmci.com!134.222.90.2!EU.net!blackbush.xlink.net!rz.uni-karlsruhe.de!news.uni-ulm.de!merlin.faw.uni-ulm.de

hallo !

I have got a question about the QueryResult-Page of SRS5, the EMBL-DB
and launching a application.

On the top of the "normal" QueryResult-Page (after I have started e.g. 
a EMBL-Query) there are 4 buttons (link, save, launch, view). 
If I then select one of the feature-links (e.g. source, exon,...), 
there are only 2 buttons left on the following Feature-Resultpage (link,
save). The other buttons (launch and view) are missing.

Is this a bug or a feature ? :-)

There is often only a small feature-Sequence (source, exon) of the whole
DNA-Sequence necessary for my application. So it would be much easier
for me to launch the application from the Feature-Resultpage, instead of
fetching the whole DNA-Sequence and extracting the feature-Sequence by
hand.

Markus

-- 
------------------------------------------------------
Markus Kieninger    Tel.:   0731/501-8758
FAW, Ulm            E-Mail: kieninge@faw.uni-ulm.de

Projekt DOPE 2 (Design of Oligonucliotide Primers)
------------------------------------------------------

From owner-srs@net.bio.net Mon Aug 18 23:00:00 1997
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.software.srs
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 19 Aug 1997 02:00:07 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 233
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199708190900.CAA20773@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.


From owner-srs@net.bio.net Mon Aug 18 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!205.252.116.205!howland.erols.net!rill.news.pipex.net!pipex!join.news.pipex.net!pipex!server1.netnews.ja.net!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Thure Etzold <etzold@ebi.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Question about QueryResult-Page
Date: Tue, 19 Aug 1997 18:21:55 +0100
Organization: EMBL-EBI
Lines: 31
Message-ID: <33F9D633.70E2E06E@ebi.ac.uk>
References: <33F9A8D0.2731@faw.uni-ulm.de>
NNTP-Posting-Host: idefix.ebi.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 4.01 [en] (Win95; I)
To: Markus Kieninger <kieninge@faw.uni-ulm.de>
X-Priority: 3 (Normal)

Markus Kieninger wrote:
> 
> hallo !
> 
> I have got a question about the QueryResult-Page of SRS5, the EMBL-DB
> and launching a application.
> 
> On the top of the "normal" QueryResult-Page (after I have started e.g.
> a EMBL-Query) there are 4 buttons (link, save, launch, view).
> If I then select one of the feature-links (e.g. source, exon,...),
> there are only 2 buttons left on the following Feature-Resultpage (link,
> save). The other buttons (launch and view) are missing.
> 
> Is this a bug or a feature ? :-)

This is definetely a feature! Since EMBL features have neither
predefined views
and also no applications both the 'view' and the 'launch' 
buttons should not be displayed. Try define a view for 'EMBL_features'
and
see if you get the 'view' button comes back. If you have an application
that runs on EMBL entries which you would also want to run on 
EMBL_features you must add attribute

contains:@DNASEQ_DATA

to the $Libformat object of EMBL_features


regards
thure

From owner-srs@net.bio.net Tue Aug 19 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!cam-news-hub1.bbnplanet.com!news.bbnplanet.com!news.maxwell.syr.edu!news-was.dfn.de!news-kar1.dfn.de!news.embl-heidelberg.de!usenet
From: Ramu Chenna <chenna@embl-heidelberg.de>
Newsgroups: bionet.software.srs
Subject: pdbfinder: author field
Date: 20 Aug 1997 09:03:37 GMT
Organization: EMBL, Heidelberg, Germany
Lines: 24
Distribution: world
Message-ID: <5tebt9$c1i@lion.embl-heidelberg.de>
NNTP-Posting-Host: shag.embl-heidelberg.de
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 1.12IS (X11; I; IRIX 5.3 IP22)
X-URL: news:bionet.software.srs?ALL

Hello 

Only the first line of the author field in pdbfinder is parsed!

  change 

  author:      ~ {$Out $In:[fields c:author] } 
                 tag /([A-Za-z.-]+\\.)([a-zA-Z ]+)/ {$Wrt:[s:"$2,$1"]} ~
to 

  author:      ~ {$Out $In:[fields c:author] } 
                 (tag /([A-Za-z.-]+\\.)([a-zA-Z ]+)/ {$Wrt:[s:"$2,$1"]})* ~

in pdbfinder.is

Ramu
-- 
_______________________________________________________________
Chenna Ramu; EMBL; Postfach 10.2209; 69012 Heidelberg; Germany.
Email: chenna@embl-heidelberg.de
   Url: http://www.embl-heidelberg.de/~chenna/
   Tel: (49) 6221 387530 (Off) ; Fax: (49) 6221 387517
______


From owner-srs@net.bio.net Wed Aug 20 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!news.bbnplanet.com!news2.chicago.cic.net!news1.chicago.cic.net!iagnet.net!portc01.blue.aol.com!newstf02.news.aol.com!newstf01.news.aol.com!audrey01.news.aol.com!not-for-mail
From: newyork212@aol.com (NewYork212)
Newsgroups: bionet.software.srs
Subject: My quest
Date: 21 Aug 1997 22:56:54 GMT
Lines: 19
Message-ID: <19970821225601.SAA28992@ladder01.news.aol.com>
NNTP-Posting-Host: ladder01.news.aol.com
X-Admin: news@aol.com
Organization: AOL http://www.aol.com

Hi name is Butterfly  a 22 year old male to female pre-op transgender from
NYC.
I am searching for information and I am hoping that someone will read this
message and help me to be pointed in the right direction.  I appreciate
any and all time and input you will offer me.

What I seek is information regarding medical insurance.....that cover
"SRS"  Sexual reassignment Surgery.  I do not have the cash, nor the
resources to make my dream come true....and I need to know which
insurances might be able to help me.  

Right now I am on Medicaid....and they won't pay....the system in NYC is
very insensitive to transgenders and their needs...and my needs...and that
why I am here seeking help through the internet....

While my name is butterfly....until I can get my wings..I am still a
caterpillar...

Thanx all

From owner-srs@net.bio.net Wed Aug 20 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!news.bbnplanet.com!newsfeed.nacamar.de!news.maxwell.syr.edu!news.cis.ohio-state.edu!magnus.acs.ohio-state.edu!ts47-4.homenet.ohio-state.edu!trostyanetsky.2
From: trostyanetsky.2@pop.service.ohio-state.edu (Leonid (Larry) Trostyanetsky)
Newsgroups: bionet.software.srs
Subject: RESEARCH ASSISTANT
Date: Thu, 21 Aug 1997 23:45:16 GMT
Organization: The Ohio State University
Lines: 27
Message-ID: <trostyanetsky.2.9.33FCD30B@pop.service.ohio-state.edu>
NNTP-Posting-Host: ts47-4.homenet.ohio-state.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #4]

RESEARCH ASSISTANT in Bioorganic Chemistry. Undergraduate student needed to
work on molecular modeling project of antitumor agent binding to DNA. Work
involves the use of modeling programs such as MacroModel and Spartan on a
dedicated SiliconGraphics Indigo Impact R10000. A great deal of
independence is possible, and the student will be expected to bring new
capabilities into the research group and to interact with other workers on
this project. Requirements for this position include successful completion
of Organic Chemistry (Chemistry 251/252/253) and experience with UNIX.
Either research credit or work-study is possible. Please contact Professor
Rob Coleman at coleman.184@osu.edu or 292-4548.


Rob

-------------------------------------------
Robert S. Coleman
Associate Professor
Department of Chemistry
The Ohio State University
100 West 18th Avenue
Columbus, OH 43210-1185
-------------------------------------------
(614) 292-4548 (voice)
(614) 292-4647 (fax)
coleman@chemistry.ohio-state.edu



From owner-srs@net.bio.net Fri Aug 22 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!infeed2.internetmci.com!newsfeed.internetmci.com!192.220.251.22!netnews.nwnet.net!news-hub.interserv.net!news.interserv.com!soft.disc7.com
From: "HURRY !" hardware@soft.disc7.com
Newsgroups: bionet.software.srs
Subject: ® ® ®  COMPUTER SOFTWARE / HARDWARE  ® ® ®
Date: Fri, 22 Aug 1997 11:21:59 -0700
Organization: VWX
Lines: 5
Message-ID: <220897112159@soft.disc7.com>
NNTP-Posting-Host: hd68-147.hil.compuserve.com

® ® ®  COMPUTER SOFTWARE / HARDWARE  ® ® ®  

                     >>> UP  TO  90 % OFF <<<

            http://www.quantcom.com/Auctionfirst><<><=<<>>==><=<><<<

From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Help for PIR in SRS5
Date: 27 Aug 1997 11:19:36 +0100
Organization: The Sanger Centre
Lines: 14
Sender: pmr@unst
Message-ID: <sub203g7wsn.fsf@sanger.ac.uk>
References: <3403F334.1EFF@infobiogen.fr>
NNTP-Posting-Host: unst.sanger.ac.uk
X-Newsreader: Gnus v5.3/Emacs 19.34

Jean-Marc Plaza <plaza@infobiogen.fr> writes:
> need help for Pir query form in SRS5.05.
> 
> When i make a query  in what ever field in 
> the query form "search PIR"(ID:hahu)
> SRS always reply : no query was specified
> (It's OK for swissprot)

I see the same effect. When I check the user.par file, there is no
query stored for PIR but there is for SWISSPROT.

No sign yet of anything obvious in the .i files or in the query forms
generated for SWISSPROT and PIR.


From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!news.apfel.de!univ-lyon1.fr!jussieu.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: Help for PIR in SRS5
Date: Wed, 27 Aug 1997 11:28:21 +0200
Organization: INFOBIOGEN
Lines: 24
Message-ID: <3403F334.1EFF@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4u)

Hi,


need help for Pir query form in SRS5.05.

When i make a query  in what ever field in 
the query form "search PIR"(ID:hahu)
SRS always reply : no query was specified
(It's OK for swissprot)
but when i make a search in pagelibinfo of PIR
for ID:HAHU the results is correct ??? 
(and also for the other fields)

All pir indices are well built


-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Ecocyc and SRS5
Date: 27 Aug 1997 09:31:16 +0100
Organization: The Sanger Centre
Lines: 10
Sender: pmr@unst
Message-ID: <sub3enw81t7.fsf@sanger.ac.uk>
References: <34033F85.2814@phu815.um.us.sbphrd.com>
NNTP-Posting-Host: unst.sanger.ac.uk
X-Newsreader: Gnus v5.3/Emacs 19.34

Filip Fuma <fumaf1@phu815.um.us.sbphrd.com> writes:
> 
> I was wondering if any has developed SRS 5 index files for
> Ecocyc metabolic libraries?

On my list of things to do. I had them for SRS4. I'm waiting for the
"next SRS5 release" before I tackle them though.

Our SRS 5 server is http://www.sanger.ac.uk/srs5/


From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!infeed1.internetmci.com!newsfeed.internetmci.com!192.48.96.126!in2.uu.net!208.198.64.1!netnews.sbphrd.com!not-for-mail
From: Filip Fuma <fumaf1@phu815.um.us.sbphrd.com>
Newsgroups: bionet.software.srs
Subject: Ecocyc and SRS5
Date: Tue, 26 Aug 1997 16:41:41 -0400
Organization: SmithKline Beecham Pharmaceuticals Research & Development
Lines: 4
Message-ID: <34033F85.2814@phu815.um.us.sbphrd.com>
NNTP-Posting-Host: phu823.sbphrd.com
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01Gold (X11; I; SunOS 5.5.1 sun4u)

I was wondering if any has developed SRS 5 index files for
Ecocyc metabolic libraries?

thanks -- ff

From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!server1.netnews.ja.net!server5.netnews.ja.net!server6.netnews.ja.net!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Help for PIR in SRS5
Date: Wed, 27 Aug 1997 13:40:51 +0100
Organization: SEQNET
Lines: 34
Distribution: bionet
Message-ID: <34042052.41C6@dl.ac.uk>
References: <3403F334.1EFF@infobiogen.fr>
NNTP-Posting-Host: s-ind2.dl.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0Gold (X11; I; IRIX 5.3 IP12)
To: Jean-Marc Plaza <plaza@infobiogen.fr>

Jean-Marc Plaza wrote:
> 
> Hi,
> 
> need help for Pir query form in SRS5.05.
> 
> When i make a query  in what ever field in
> the query form "search PIR"(ID:hahu)
> SRS always reply : no query was specified
> (It's OK for swissprot)
> but when i make a search in pagelibinfo of PIR
> for ID:HAHU the results is correct ???
> (and also for the other fields)
> 
> All pir indices are well built

Over here it appears to work...  I don't recall having done
anything special to make it so. 


(Euh - yes, indeed, this doesn't realy help you solving your problem,
but I though you might like to know that it can be done..)

Martin

-- 
-------------------------------------------------------------------
| Martin Hilbers http://www.dci.clrc.ac.uk/Person.asp?m.p.hilbers |
| SEQNET                |     E-mail: m.p.hilbers@dl.ac.uk        |
| Daresbury Laboratory  |     Tel:    +44-1925-603492             |
| Daresbury, Warrington |     Fax:    +44-1925-603100             |
| Cheshire WA4 4AD      | SEQNET is the UK national EMBNet node   |
| United Kingdom        |     http://www.seqnet.dl.ac.uk/         |
-------------------------------------------------------------------

From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!daresbury!uninett.no!Norway.EU.net!EU.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Help for PIR in SRS5
Date: 27 Aug 1997 16:28:23 +0100
Organization: The Sanger Centre
Lines: 18
Sender: pmr@unst
Distribution: bionet
Message-ID: <subzpq37ii0.fsf@sanger.ac.uk>
References: <3403F334.1EFF@infobiogen.fr> <34042052.41C6@dl.ac.uk>
NNTP-Posting-Host: unst.sanger.ac.uk
X-Newsreader: Gnus v5.3/Emacs 19.34

Martin Hilbers <mph@dl.ac.uk> writes:
> Jean-Marc Plaza wrote:
> > need help for Pir query form in SRS5.05.
> 
> Over here it appears to work...  I don't recall having done
> anything special to make it so. 

Funny - seems to be just Sanger and InfoBiogen that have problems.

OK, next possibility: We're running our SRS5 server on OSF.


-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-srs@net.bio.net Tue Aug 26 23:00:00 1997
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!4.1.16.34!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!server1.netnews.ja.net!server5.netnews.ja.net!daresbury!usenet
From: Martin Hilbers <mph@dl.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Help for PIR in SRS5
Date: Wed, 27 Aug 1997 16:43:13 +0100
Organization: SEQNET
Lines: 25
Distribution: bionet
Message-ID: <34044B10.41C6@dl.ac.uk>
References: <3403F334.1EFF@infobiogen.fr> <34042052.41C6@dl.ac.uk> <subzpq37ii0.fsf@sanger.ac.uk>
NNTP-Posting-Host: s-ind2.dl.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.0Gold (X11; I; IRIX 5.3 IP12)

Peter Rice wrote:
> 
> Martin Hilbers <mph@dl.ac.uk> writes:
> > Jean-Marc Plaza wrote:
> > > need help for Pir query form in SRS5.05.
> >
> > Over here it appears to work...  I don't recall having done
> > anything special to make it so.
> 
> Funny - seems to be just Sanger and InfoBiogen that have problems.
> 
> OK, next possibility: We're running our SRS5 server on OSF.
> 

Nope - We're also running it on OSF

-- 
-------------------------------------------------------------------
| Martin Hilbers http://www.dci.clrc.ac.uk/Person.asp?m.p.hilbers |
| SEQNET                |     E-mail: m.p.hilbers@dl.ac.uk        |
| Daresbury Laboratory  |     Tel:    +44-1925-603492             |
| Daresbury, Warrington |     Fax:    +44-1925-603100             |
| Cheshire WA4 4AD      | SEQNET is the UK national EMBNet node   |
| United Kingdom        |     http://www.seqnet.dl.ac.uk/         |
-------------------------------------------------------------------

From owner-srs@net.bio.net Wed Aug 27 23:00:00 1997
Path: biosci!agate!newsfeed.kornet.nm.kr!howland.erols.net!newsxfer3.itd.umich.edu!oleane!jussieu.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: DATABANKSin SRS5
Date: Thu, 28 Aug 1997 12:19:14 +0200
Organization: INFOBIOGEN
Lines: 20
Message-ID: <340550A2.7834@infobiogen.fr>
NNTP-Posting-Host: lovelace.infobiogen.fr
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (X11; I; SunOS 5.5.1 sun4u)

Hi,

concerning the icarus files databanks.i and 
databanks.is, is there a script already done to generate
databank flat file ?

Regards





-- 
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------

From owner-srs@net.bio.net Wed Aug 27 23:00:00 1997
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!baron.netcom.net.uk!netcom.net.uk!server3.netnews.ja.net!news.ox.ac.uk!not-for-mail
From: johnp@worf.molbiol.ox.ac.uk (John Peden)
Newsgroups: bionet.software.srs
Subject: Does getz have a memory leak
Date: 28 Aug 1997 12:20:30 GMT
Organization: Oxford University
Lines: 29
Message-ID: <5u3qee$fps$3@news.ox.ac.uk>
Reply-To: johnp@molbiol.ox.ac.uk
NNTP-Posting-Host: udcpc3.jr2.ox.ac.uk
X-Newsreader: News Version 5.0 from Hummingbird Communications Ltd.

Hi,

Problem on Digital UNIX 4.0 and SRS

I have been having trouble with a memory leak in getz for several months, the leak was present in SRS4 and is still
present in SRS5.05. The problem occurs when multiple sequence entries are read from disk and written to standard 
output. Memory is allocated to hold each sequence when it is read, but the memory is not released after the 
sequence has been written to the standard out. This process repeats until memory is exhausted. 

I have checked for memory leaks in getz using PURIFY, and cannot find any. I have also checked the getz /SRS 
code, and while memory is being allocated for each sequence object via EntryOpen(), it is apparently being 
correctly released by a EntryClose() call, on an entry by entry basis.

I am therefore confused where this problem is occurring and whether this is a SRS or Digital UNIX or
compiler specific problem and would appreciate confirmation that the problem does or does not occur on 
other systems/setups.

A typical getz query:

getz -sf fasta -f  "id des seq"  "[libs={genbank embl}-sl#45:] ! ([libs-org:escherichia coli]  |  [libs-org:metazoa])" 


After the query is processed and the first sequence is outputted, my memory usage is approximately 34Mb. 
However on my system memory usage continues to grow until it hits either the soft or hard memory limit
(the hard limit is 600 Mb). 

John

Oxfrord University Molecular Biology Data Centre.

From owner-srs@net.bio.net Wed Aug 27 23:00:00 1997
Path: biosci!daresbury!uninett.no!Norway.EU.net!EU.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Does getz have a memory leak
Date: 28 Aug 1997 16:50:11 +0100
Organization: The Sanger Centre
Lines: 37
Sender: pmr@unst
Message-ID: <subyb5m71e4.fsf@sanger.ac.uk>
References: <5u3qee$fps$3@news.ox.ac.uk>
NNTP-Posting-Host: unst.sanger.ac.uk
X-Newsreader: Gnus v5.3/Emacs 19.34

johnp@worf.molbiol.ox.ac.uk (John Peden) writes:
> Problem on Digital UNIX 4.0 and SRS
> 
> I have been having trouble with a memory leak in getz for several months, the leak was present in SRS4 and is still
> present in SRS5.05. The problem occurs when multiple sequence entries are read from disk and written to standard 
> output. Memory is allocated to hold each sequence when it is read, but the memory is not released after the 
> sequence has been written to the standard out. This process repeats until memory is exhausted. 
> 
> getz -sf fasta -f  "id des seq"  "[libs={genbank embl}-sl#45:] ! ([libs-org:escherichia coli]  |  [libs-org:metazoa])" 
> 
> 
> After the query is processed and the first sequence is outputted, my memory usage is approximately 34Mb. 
> However on my system memory usage continues to grow until it hits either the soft or hard memory limit
> (the hard limit is 600 Mb). 

I tried this (using emblnew in place of genbank) on our Digital UNIX
4.0 system. "top" showed "SIZE: 45M RES: 29M" when the output
started. I guess the exact sizes depend on the databases being used.

The SIZE and RES figures did indeed creep up as the sequences were
written. That's a lot of sequences for one query, so I didn't wait for
the end :-)

Could this be somewhere in the parser, for example as the sequence
is being read by Icarus?

We use EMBL and EMBLNEW in the original flatfile format, but we have
made some changes to the embl.is file because in FASTA format there
was no ID for flatfile format databases (all a question of forcing the
ID to be parsed).

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-srs@net.bio.net Fri Aug 29 23:00:00 1997
Path: biosci!bloom-beacon.mit.edu!eru.mt.luth.se!feed1.news.erols.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!infeed1.internetmci.com!newsfeed.internetmci.com!192.220.251.22!netnews.nwnet.net!news-hub.interserv.net!news.interserv.com!discount-software5.com
From: "DISCOUNTS !" software@discount-software5.com
Newsgroups: bionet.software.srs
Subject: >>> COMPUTER SOFTWARE / HARDWARE <<<
Date: Sat, 30 Aug 1997 00:14:26 -0700
Organization: PQR
Lines: 5
Message-ID: <300897001426@discount-software5.com>
NNTP-Posting-Host: hd14-083.hil.compuserve.com

<<<<<<<  COMPUTER SOFTWARE / HARDWARE  >>>>>>>

                            >>> UP  TO  90 % OFF <<<

                  http://www.quantcom.com/auctionfirst/=<>>=<==<=>==<<=><=>

From owner-srs@net.bio.net Sat Aug 30 23:00:00 1997
Path: biosci!agate!usenet
From: Michael Schmitz <schmitz@lcbvax.cchem.berkeley.edu>
Newsgroups: bionet.software.srs
Subject: Re: Does getz have a memory leak
Date: Sat, 30 Aug 1997 17:51:29 -0700
Organization: Tinoco Lab, UC Berkeley
Lines: 19
Message-ID: <3408BFC4.4C92@lcbvax.cchem.berkeley.edu>
References: <5u3qee$fps$3@news.ox.ac.uk> <subyb5m71e4.fsf@sanger.ac.uk>
NNTP-Posting-Host: tinocopwr.cchem.berkeley.edu
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (Macintosh; I; PPC)

Peter Rice wrote:
> > I have been having trouble with a memory leak in getz for several months, 
> >the leak was present in SRS4 and is still present in SRS5.05.
> The SIZE and RES figures did indeed creep up as the sequences were
> written. That's a lot of sequences for one query, so I didn't wait for
> the end :-)
> 
> Could this be somewhere in the parser, for example as the sequence
> is being read by Icarus?

Wasn't Icarus invented in SRS 5?? But a memory leak like this doesn't
necessarily
mean the sequence isn't freed. There may be other data structures, and
SRS 4 had 
at least one problem with 'forgetting' pointers to malloced data. I
don't remember  details now, but it involved keeping multiple pointers
to certain structures. 

	Michael

From owner-srs@net.bio.net Sun Aug 31 23:00:00 1997
Path: biosci!agate!newsfeed.kornet.nm.kr!xfer.kren.nm.kr!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!cam-news-feed3.bbnplanet.com!news.bbnplanet.com!zylum.nettrip.net!not-for-mail
From: Nick@tzcc.com (Nick Dinielli (The Fatman))
Newsgroups: bionet.software.srs
Subject: For additional software support visit:  http://www.tzcc.com
Date: Mon, 01 Sep 1997 02:48:43 GMT
Organization: NetTrip, Inc.
Lines: 2
Message-ID: <32fd6e1a.6974104@news.carroll.com>
Reply-To: Nick@tzcc.com
NNTP-Posting-Host: nj-tc1-080.nettrip.net
Mime-Version: 1.0
Content-Type: text/plain
X-Newsreader: Forte Agent 1.0/32.390MH


For additional software support visit:  http://www.tzcc.com

