From owner-srs@net.bio.net Tue Dec 01 22:00:00 1998
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Newsgroups: bionet.software.srs
Subject: NetSpy permits to supervise the task on the remote PC.
From: fax_na@hotmail.com (A.E.)
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Date: Wed, 02 Dec 1998 13:36:50 GMT
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NetSpy permits to supervise the task on the remote PC.
It is useful tool for manager to see what the personnel is doing during the
work time.
NetSpy work in Win NT 4.x or Windows 95 (98) netowrk environment
using TCP/IP.

NetSpy consistes of 2parts  - server (NetSpyS) and client (Raposa).

The NetSpyS runs as minimized window. It is Gui application
Default TCP/IP port number is 79 for connection with client (Raposa).

(In demo version NetSpyS presents advetizing string read fron the host
UACT.NET. In this state NetSpyS is Always-on-top window)

It ispossible to use other port number,creating specila NetSpy.INI file and
put this file into the Windows directory. This file should have the following contents:

[Communication]
Port = 99

for port number 99 for example.

Client Raposa is console Windows application.
It should be started from virtual DOS (DOS-PROMT) by typing the following command
string:

>Raposa  network_remote_computer_name/IP__remote_computer [port_number]

By default the port number is 79 (Finger TCP/IP port - 79).

Port number should be the same as used by NetspyS.

Example of Raposa stating:

C:\WINNT40>raposa 127.0.0.1  99

or

C:\WINNT40>raposa ts1p12.uact.net

If connection was succesful the client Raposa would present the list
of tasks on the remote compute, for example:

E:\DOWN>a:\netspy\raposa 127.0.0.1  80

NetSpy Client Part. Questions: fax_na@hotmail.com
Connected to [127.0.0.1:80].

Conneted to the NetSpy Server
Host Name: gwork_a
The current date and time are: Fri Oct 16 20:15:20 1998

              Task Report

1.  Mimimized  NoZoomed Name: NetSpy Server Part
2.  NoMimimized  NoZoomed Name: NetDDE Agent
3.  NoMimimized  NoZoomed Name: Shortcut to cmd - a:\netspy\raposa 127.0.0.1  80

4.  NoMimimized  NoZoomed Name: Battery Meter
5.  NoMimimized  NoZoomed Name: OleMainThreadWndName
6.  NoMimimized  NoZoomed Name: Program Manager


Done!

E:\DOWN>

If you want to receive the sources of NetSpy or not-demo version 
(without demo string) please write to:
fax_na@hotmail.com













From owner-srs@net.bio.net Tue Dec 01 22:00:00 1998
Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!xmission!nntp.csuchico.edu!cscnews.csc.calpoly.edu!nntp-server.caltech.edu!seqaxp.bio.caltech.edu!MATHOG
From: mathog@seqaxp.bio.caltech.edu
Newsgroups: bionet.software.srs
Subject: getz syntax question
Date: 2 Dec 1998 18:33:20 GMT
Organization: Biology Division, Caltech, Pasadena CA 91125
Lines: 57
Message-ID: <74415g$nla@gap.cco.caltech.edu>
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SRS 5.1 on Linux/Intel.

Can somebody please explain to me how to get from the query description
language in the html page to the following observed behavior?   Yes, this
started out as a typo, but since it doesn't throw an error, it is 
apparently allowed syntax.

All of these rapidly return a list of all SWISSPROT entries:

  % getz 'swissprot-id:ha12_mouse'
  % getz 'swissprot-id'
  % getz 'swissprot'

but

  % getz 'swiss'
  SRSICA:srsquery.i:51:  error: unknown set or databank. "swiss"

It looks like all databases are predefined as "sets", and also getz will
return a "set" even if no operators are present on the query line.  However,
how the parser handles the first two commands above is very unclear.  Also,
this doesn't do what I'd expect if the preceding was the full explanation: 

  % getz '{nrl3d swissprot}'

since it returns NOTHING, why not both?  Elsewhere {database database} can
be used anywhere that "database" alone can.

  % getz 'nrl3d | swissprot'

returns both sets, swissprot first.  So the logical operators function
in this context, but not the {} operator.

One interesting side note, the "obvious" methods of listing a database take
orders of magnitude longer than the methods described above. On a 400 Mhz
PII, all SRS databases on a single 9 Gb U2W scsi disk, no other load on
system: 

  % getz 'swissprot' > /dev/null 

took 3 seconds, but

  % getz '[swissprot-id:*]' > /dev/null

took 423 seconds.

(The fastest method of all to get this information was 

  % cat swissprot.seqcat > /dev/null

which took lesss than a second, but not all sites will have that GCG file.)

Regards,

David Mathog
mathog@seqaxp.bio.caltech.edu
Manager, sequence analysis facility, biology division, Caltech 

From owner-srs@net.bio.net Tue Dec 01 22:00:00 1998
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: New Application in SRS
Date: Wed, 02 Dec 1998 13:37:54 +0100
Organization: INFOBIOGEN
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Hello,

We have an application called  b2f that i would like to set in SRS.
This application only needs as input a blast output.

I defined for B2F_APP a datatype for proteins
 (dataType:@PROTSEQ_DATA)
and I add it in srsgen.i(@B2F_APP in PROTSEQ_DATA).

By this way, B2F appears (launch botton) after a query result for
proteins
and also for blast result.
Is there a way to get it only for blast result ?

Thanks for your help in advance,


Jean-Marc

--
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------




From owner-srs@net.bio.net Thu Dec 03 22:00:00 1998
Path: biosci!YAHOO.COM!mri87492
From: mri87492@YAHOO.COM
Newsgroups: bionet.software.srs
Subject: your site
Date: 4 Dec 1998 00:33:14 -0800
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From owner-srs@net.bio.net Thu Dec 03 22:00:00 1998
Path: biosci!news.stanford.edu!newsfeed.concentric.net!howland.erols.net!newsfeed.nacamar.de!univ-lyon1.fr!jussieu.fr!infobiogen.fr!newsmaster
From: Jean-Marc Plaza <plaza@infobiogen.fr>
Newsgroups: bionet.software.srs
Subject: embl search in SRS
Date: Fri, 04 Dec 1998 11:30:40 +0100
Organization: INFOBIOGEN
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hello all,

I find a problem using parentheses for embl search :

no entries found, query: "[embl-Description: alpha* & (globin*|hemoglobin*)] "

but
Query "[embl-Description: alpha* & globin*|hemoglobin*] " found 12032 entries
Query "[embl-Description: alpha* & globin*] " found 2144 entries
Query "[embl-Description: alpha* & hemoglobin*] " found 5157 entries

The query search with lookup is ok.

Regards

--
---------------------------------------------------
Jean-Marc PLAZA
INFOBIOGEN - CNRS
7, rue Guy Moquet BP8 94801 VILLEJUIF Cedex, France
tel: +33 45 59 52 39  fax: +33 45 59 52 50
e-mail: plaza@infobiogen.fr
---------------------------------------------------




From owner-srs@net.bio.net Thu Dec 03 22:00:00 1998
Path: biosci!news.stanford.edu!su-news-feed2.bbnplanet.com!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.gtei.net!newsfeed.cwix.com!158.43.192.17!rill.news.pipex.net!pipex!server1.netnews.ja.net!pegasus.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: embl search in SRS
Date: 04 Dec 1998 13:38:10 +0000
Organization: The Sanger Centre
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Jean-Marc Plaza <plaza@infobiogen.fr> writes:
> I find a problem using parentheses for embl search :
> 
> no entries found, query: "[embl-Description: alpha* & (globin*|hemoglobin*)] "

Seems that parentheses are badly broken:

getz '[swissprot-authors:drew* & rice*]'  -> 1 entry
getz '[swissprot-authors:(drew* & rice*)]'  -> nothing

But the SRS manual offers as an example:

[medline-authors:(wu* & rice*) ! (smith* | jones*)]

so we are apparently using the 'correct' syntax.

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-srs@net.bio.net Sun Dec 06 22:00:00 1998
Path: biosci!news.stanford.edu!logbridge.uoregon.edu!newsfeed1.swip.net!swipnet!rill.news.pipex.net!pipex!uunet!in1.uu.net!news1-gui.server.ntli.net!news-feed.ntli.net!news5-gui.server.ntli.net!news-feed.ntli.net!server4.netnews.ja.net!server2.netnews.ja.net!pegasus.csx.cam.ac.uk!not-for-mail
From: timc@chiark.greenend.org.uk (Tim Cutts)
Newsgroups: bionet.software.srs
Subject: Indexing of RL lines from EMBL
Date: 07 Dec 1998 10:14:52 +0000 (GMT)
Organization: Linux Unlimited
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NNTP-Posting-Host: rrw1000.sel.cam.ac.uk
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The current EMBL parser only indexes the RL field if it conforms to a
published reference.  It would be useful to be able to search the
database for information from other entries, so I could, for example,
ask "Give me all the entries submitted by this organisation".  Has
anyone already done this to the EMBL parser, just so that I can avoid
reinventing the wheel...

Tim.

From owner-srs@net.bio.net Tue Dec 08 22:00:00 1998
Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.tli.de!newsfeed.wirehub.nl!news.belnet.be!surfnet.nl!barba.uci.kun.nl!sci.kun.nl!not-for-mail
From: "K. Cuelenaere" <koenc@caos.kun.nl>
Newsgroups: bionet.software.srs
Subject: Re: embl search in SRS
Date: Wed, 09 Dec 1998 11:40:17 +0100
Organization: CAOS/CAMM Center
Lines: 34
Message-ID: <366E5391.70A94C3C@caos.kun.nl>
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Peter Rice wrote:
> 
> Jean-Marc Plaza <plaza@infobiogen.fr> writes:
> > I find a problem using parentheses for embl search :
> >
> > no entries found, query: "[embl-Description: alpha* & (globin*|hemoglobin*)] "
> 
> Seems that parentheses are badly broken:
> 
> getz '[swissprot-authors:drew* & rice*]'  -> 1 entry
> getz '[swissprot-authors:(drew* & rice*)]'  -> nothing
> 
> But the SRS manual offers as an example:
> 
> [medline-authors:(wu* & rice*) ! (smith* | jones*)]
> 
> so we are apparently using the 'correct' syntax.

Hi,

 Jack noted the same problem some time ago and mentioned it
to Thure. Thure confirmed the parentheses problem and I believe
he said it will be back in the next release,

Regards,
Koen.
--------------------------------------------------------------
Koen Cuelenaere			Email: koenc@caos.kun.nl
CAOS/CAMM Center		Phone: +31 24 3653383
University of Nijmegen		Fax:   +31 24 3652977
Toernooiveld
6525 ED Nijmegen
The Netherlands			URL: http://www.caos.kun.nl/
--------------------------------------------------------------

From owner-srs@net.bio.net Wed Dec 09 22:00:00 1998
Path: biosci!AOL.COM!Gangst2219
From: Gangst2219@AOL.COM
Newsgroups: bionet.software.srs
Subject: Publishing Company For Sale
Date: 10 Dec 1998 01:13:32 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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From owner-srs@net.bio.net Wed Dec 09 22:00:00 1998
Message-ID: <366CDFD5.7F1F9CA2@igbm.unil.ch>
Date: Tue, 08 Dec 1998 08:14:14 +0000
From: Marco Pagni <Marco.Pagni@igbm.unil.ch>
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Subject: Re: List of queries with getz
References: <365A92E2.C1144E31@igs.cnrs-mrs.fr> <365AAEDF.B5907AFA@ebi.ac.uk> <subhfvpfbb1.fsf@unst.sanger.ac.uk>
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Peter Rice wrote:

> Heikki Lehvaslaiho <heikki@ebi.ac.uk> writes:
>
> > Olivier POIROT wrote:
> > > Is it possible to use a file containing a list of Ids with getz (SRS
> > > version 5.1)?
> > Dear Olivier,
> > I suppose you mean lists like these:
> > %  more  my.list
> > EMBL:AB015259
> > EMBL:AB015260
> > EMBL:AB015261
> > EMBL:AB015262
> > %
> > getz needs its input formatted in a slightly different way. Let's
> > write a script, in icarus of course, that does what you want and can
> > be extended as needed.
>
> Not really what is needed. That Icarus script just runs getz for each
> sequence and writes the results to stdout.
>
> I have asked Thure several times for the SRS 4 capability to use a list
> of entries as a query. Then you can do things like:
>
> getz '@my.list > swissprot'
> getz '@my.list' -f 'id acc des'
> getz '@my.list ! (embl < emblnew)'
>
> So far no sign of this appearing, though Thure promised it was not
> difficult.  I really miss this capability. The lists can be created by
> getz (they are the default output) but cannot be used since SRS 4 went
> away.
>
> --
> ----------------------------------------------------------------------
> Peter Rice                | Informatics Division, The Sanger Centre,
> E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
> Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
> Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

I have exactely the same need, and I am sure that we are more than two SRS
users with the same need. The rationale for this is that  SRS  outputs
reflect the
databases content which are not free from erroneous annotations. To be
fully biologically
significant,  a few entries must often be added to or removed from result
sets. And
unfortunately such "manually" corrected cannot be read by SRS as input for
further
querying databases.

Regards,

Marco Pagni
Swiss Institute of Bioinformatics
mpagni@igbm.unil.ch


From owner-srs@net.bio.net Thu Dec 10 22:00:00 1998
Path: biosci!daresbury!server5.netnews.ja.net!server6.netnews.ja.net!nntp.news.xara.net!xara.net!news.maxwell.syr.edu!news-peer.gip.net!news-dc.gip.net!news.gsl.net!gip.net!duke.telepac.pt!news.telepac.pt!194.65.24.2!152.205.178.172
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Newsgroups: bionet.software.srs
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Lines: 12
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NNTP-Posting-Host: 194.65.24.2

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From owner-srs@net.bio.net Fri Dec 11 22:00:00 1998
Path: biosci!news.stanford.edu!su-news-feed2.bbnplanet.com!su-news-hub1.bbnplanet.com!news.gtei.net!logbridge.uoregon.edu!newspeer1.nac.net!netnews.com!news2.euro.net!news.telekabel.nl!not-for-mail
From: "rob willemse" <rowi@telekabel.nl>
Newsgroups: bionet.software.srs
Subject: FTP superfast
Date: Sat, 12 Dec 1998 16:37:54 +0100
Organization: TeleKabel
Lines: 5
Message-ID: <74u2k4$296$1@news.telekabel.nl>
NNTP-Posting-Host: n078.wageningen.telekabel.euronet.nl
X-Trace: news.telekabel.nl 913477060 2342 194.134.133.83 (12 Dec 1998 15:37:40 GMT)
NNTP-Posting-Date: 12 Dec 1998 15:37:40 GMT
X-Newsreader: Microsoft Outlook Express 4.72.3110.5
X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3

Go here for free and shareware very fast cable modem 300kbs
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From owner-srs@net.bio.net Wed Dec 16 22:00:00 1998
From: "Thure Etzold" <etzold@lionbio.co.uk>
Newsgroups: bionet.software.srs
Subject: job opportunities within the SRS project at LION Bioscience, Cambridge
Date: Thu, 17 Dec 1998 21:58:05 -0000
X-Newsreader: Microsoft Outlook Express 4.72.3110.5
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Message-ID: <36797e7a.0@nnrp1.news.uk.psi.net>
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Lines: 80


LION Bioscience Ltd. is a subsidiary of LION Bioscience AG.
LION is unique in the integration of a complete collection of
proprietary genomics technologies ranging from experimen-
tal biology to information technology. LION's goal is to
become the leading provider of biological knowledge to the
life science industry. Biological knowledge is the outcome of
customised genomics projects, target gene identification,
and informatics tools to most rapidly and effectively capital-
ise on the results.

LION Bioscience Ltd. is based in Cambridge, UK, and
focuses on commercial development of the SRS software
system. SRS is a data retrieval system that integrates
heterogeneous databanks in molecular biology and
genome analysis. There are currently several dozen
servers world-wide that provide access to over 300
different databanks via the World Wide Web. Additional
technology to integrate externally developed applications
into the package gives novel and powerful capabilities for
biological data analysis.

LION offers an exciting start-up environment with a bright
and energetic team. Information about LION Bioscience is
available on the web at http://www.lion-ag.de.  LION is
looking for scientists and engineers to join our enthusiastic
and fast-moving team in the following areas.

Software Engineers   (30-40k)
Experienced software engineers to work on the SRS project.
SRS is evolving and growing rapidly and provides a unique
set of networking and data management challenges. This
forces us to evaluate and use the latest software technolo-
gies and develop novel solutions ourselves. Qualifications
include fluency in the C language, and comfort participating
in a large software development project. A background in
biology or experience in HTML, Java and object-oriented
programming would be welcome.

Q/A Engineers   (30-40k)
Software Quality Assurance engineers experienced in
developing and implementing Q/A plans, software testing
suites, and bug tracking systems. Should be familiar with
biological software applications and data, and capable of
interacting with software engineers.

Documentation Lead   (25-35k)
Experienced writer to lead the software documentation
effort. Responsibilities will include the writing of a user
manual, administrator manual, online help, and quick
reference guides. Candidates should either have a strong
background as a user of bioinformatics software or a strong
background in software documentation. The company will
train in the other discipline.

Customer Service   (25-35k)
Scientists to provide high-quality technical and scientific
support to our installed customer base. Responsibilities will
include the establishment of a call centre, case tracking and
reporting software as well as responding to and interacting
with customers to quickly solve problems. Additional
responsibilities include travel to customer sites to install,
upgrade, maintain, and customise installations. Strong tech-
nical and communications skills are necessary.

Please send your resume to CV to jobs@lionbio.co.uk.


LION Bioscience Ltd.
Sheraton House
Castle Park
Cambridge
CB3 0AX
United Kingdom
Phone: +44 (0) 1223 224 700
Fax: +44 (0) 1223 224-701





From owner-srs@net.bio.net Thu Dec 17 22:00:00 1998
Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!rill.news.pipex.net!pipex!ams.news.uu.net!uunet!in5.uu.net!stalker.oem.net!not-for-mail
From: "Sean" <biostorm@biostorm.com>
Newsgroups: bionet.software.srs
Subject: Universal Software
Date: Tue, 15 Dec 1998 05:01:40 -0500
Organization: oemnetworks.com
Lines: 28
Message-ID: <36758784.0@rboc1.prime-x.net>
NNTP-Posting-Host: rboc1.prime-x.net
X-Newsreader: Microsoft Outlook Express 4.72.2106.4
X-MimeOLE: Produced By Microsoft MimeOLE V4.72.2106.4

Thought this might be of interest-- my name is Sean Hughes and Im with
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Software 18 Windows, 14 Mac, 24 DOS.
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----------------------------------------------------------------------------
-----------------------------------------




From owner-srs@net.bio.net Thu Dec 17 22:00:00 1998
Path: biosci!agate!newsfeed.berkeley.edu!btnet-peer!btnet!nntp.news.xara.net!xara.net!server6.netnews.ja.net!server4.netnews.ja.net!server2.netnews.ja.net!hgmp.mrc.ac.uk!not-for-mail
From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: job opportunities within the SRS project at LION Bioscience, Cambridge
Date: 18 Dec 1998 09:49:29 +0000
Organization: The Sanger Centre
Lines: 17
Message-ID: <sub4sqtaifq.fsf@unst.sanger.ac.uk>
References: <36797e7a.0@nnrp1.news.uk.psi.net>
NNTP-Posting-Host: unst.sanger.ac.uk
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X-Complaints-To: news@hgmp.mrc.ac.uk
NNTP-Posting-Date: 18 Dec 1998 09:47:13 GMT
X-Newsreader: Gnus v5.5/Emacs 20.2

"Thure Etzold" <etzold@lionbio.co.uk> writes:

> LION Bioscience Ltd. is based in Cambridge, UK, and
> focuses on commercial development of the SRS software
> system

Careful Thure - there are restrictions on commercial activities in the
BIOSCI/bionet newsgroups. I assume this posting was cleared first.

See http://net.bio.net/BIOSCI/biosci.FAQ.html

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-srs@net.bio.net Fri Dec 18 22:00:00 1998
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.software.srs
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 19 Dec 1998 02:00:11 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 233
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199812191000.CAA03712@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.


From owner-srs@net.bio.net Sat Dec 19 22:00:00 1998
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.maxwell.syr.edu!nntp.ntr.net!Supernews60!supernews.com!uunet!in3.uu.net!satlink!ul3.satlink.com!not-for-mail
From: File Detect <File@Detect.com>
Newsgroups: bionet.software.srs
Subject: Useful program
Date: Sun, 20 Dec 1998 00:15:08 -0600
Organization: Marsc
Lines: 71
Message-ID: <367C95EB.96198BA2@Detect.com>
NNTP-Posting-Host: maq033b.advance.com.ar
Mime-Version: 1.0
Content-Type: multipart/alternative; boundary="------------15580F8F48C8662D2EF4209C"
X-Mailer: Mozilla 4.03 [en] (Win95; I)


--------------15580F8F48C8662D2EF4209C
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit

File Detect:

File Detect is a Windows 95 program.
This program detects new, modified or deleted files in your disk.
Also detects new or deleted folders (Directories).
This is very useful to know what files (As to be *.DLL's, *.OCX's,
*.TTF's
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program,
driver or make a change in the system configuration.

As you know, when you install a program or driver in your disk, a lot of

files are installed in your system folders, Some times you uninstall a
program
and these files remain there occupying several MB of space in your disk.

Think about it. How many times do you download a program from the
Internet?.
How many games?.
With File Detect you can take control on this situation since all what
is
copied to your disk is detected.

For more information about this program and for downloading it visit
the home page: www.angelfire.com/fl/filedetect



--------------15580F8F48C8662D2EF4209C
Content-Type: text/html; charset=us-ascii
Content-Transfer-Encoding: 7bit

<HTML>
<B><FONT SIZE=+1>File Detect:</FONT></B>

<P>File Detect is a Windows 95 program.
<BR>This program detects new, modified or deleted files in your disk.
<BR>Also detects new or deleted folders (Directories).
<BR>This is very useful to know what files (As to be *.DLL's, *.OCX's,
*.TTF's
<BR>*.HLP's and many other) are copied to your disk when you install a
new program,
<BR>driver or make a change in the system configuration.

<P>As you know, when you install a program or driver in your disk, a lot
of
<BR>files are installed in your system folders, Some times you uninstall
a program
<BR>and these files remain there occupying several MB of space in your
disk.

<P>Think about it. How many times do you download a program from the Internet?.
<BR>How many games?.
<BR>With File Detect you can take control on this situation since all what
is
<BR>copied to your disk is detected.

<P>For more information about this program and for downloading it visit
<BR>the <A HREF="http://www.angelfire.com/fl/filedetect">home page: www.angelfire.com/fl/filedetect</A>
<BR>&nbsp;
<BR>&nbsp;</HTML>

--------------15580F8F48C8662D2EF4209C--



From owner-srs@net.bio.net Tue Dec 22 22:00:00 1998
Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail
From: stuart@ludwig.ucl.ac.uk (Stuart Rison)
Newsgroups: bionet.software.srs
Subject: Spanning multiple SRS servers.
Date: 23 Dec 1998 13:49:59 -0000
Organization: Daresbury Laboratory, Warrington, U.K.
Lines: 24
Message-ID: <75qse7$fg7$1@mserv2.dl.ac.uk>
NNTP-Posting-Host: mserv2.dl.ac.uk
Original-To: bio-soft@dl.ac.uk, bio-srs@dl.ac.uk
content-length: 817
Return-Path: <stuart@ludwig.ucl.ac.uk>


Dear all,

I would like to query Unigene (the clustred EST database) and dbEST (the EST
database) with SRS simultaneously.  Unfortnately, I have not yet found an
SRS server that provides indexing for BOTH of them (searched using SRS on
databanks).

Is it possible to 'save' data and pass them from one server to another?
For example, could I pull a list of EST accesion numbers from dbEST on
one server, save that set of accession numbers and get hold of all the
clusters in UniGene that contain these EST accession numbers?

I do not have that facilities to index dbEST and UniGene 'in house'.

could you please cc your postings to stuart@NO_JUNK.ludwig.ucl.ac.uk (with NO_JUNK removed)
as I am currently unable to check on newsgroups regularly.

Thanks for any help you may provide.

best regards,

Stuart Rison.


From owner-srs@net.bio.net Tue Dec 22 22:00:00 1998
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From: stuart@ludwig.ucl.ac.uk (Stuart Rison)
Newsgroups: bionet.software.srs
Subject: Spanning multiple SRS servers... addendum.
Date: 23 Dec 1998 14:03:56 -0000
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Dear All,

>Unfortnately, I have not yet found an SRS server that provides indexing for BOTH of them
>(searched using SRS on
databanks).

Must have searched very badly or been very tired!  Found plenty of such servers
now!

All the same, I am curious to know if the passing of data between servers is
possible should I ever find myself in such a situation again.

best regards,

Stuart
stuart@NO_JUNK.ludwig.ucl.ac.uk

From owner-srs@net.bio.net Mon Dec 28 22:00:00 1998
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From: Peter Rice <pmr@sanger.ac.uk>
Newsgroups: bionet.software.srs
Subject: Re: Spanning multiple SRS servers.
Date: 29 Dec 1998 09:38:46 +0000
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stuart@ludwig.ucl.ac.uk (Stuart Rison) writes:
> I would like to query Unigene (the clustred EST database) and dbEST (the EST
> database) with SRS simultaneously.  Unfortnately, I have not yet found an
> SRS server that provides indexing for BOTH of them (searched using SRS on
> databanks).

As you found, there are several servers with both.

You need to take care over how the databases are linked.  At the
Sanger Centre we link UNIGENE and DBEST using the CloneID rather than
the accession number. SRS only allows one link between databases.

You would need to use EMBL to get links by accession number.
We also have DBESTSEQ (the dbEST FASTA format sequences file) but
that currently has no direct link to UNIGENE.

-- 
----------------------------------------------------------------------
Peter Rice                | Informatics Division, The Sanger Centre,
E-mail: pmr@sanger.ac.uk  | Wellcome Trust Genome Campus,
Tel: (44) 1223 494967     | Hinxton, Cambridge, CB10 1SA, England
Fax: (44) 1223 494919     | URL: http://www.sanger.ac.uk/Users/pmr/

From owner-srs@net.bio.net Wed Dec 30 22:00:00 1998
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From: bioinfo@my-dejanews.com
Newsgroups: bionet.software.srs
Subject: Algorithm for Restriction Enzyme Analysis
Date: Thu, 31 Dec 1998 05:05:55 GMT
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Hi All,
I am in trouble. I am developing an algorithm for restriction enzyme analysis
but it is taking too long. The reason is because there are so many degenerate
bases in the DNA sequence and thus it takes very long to analyze for all of
them considering the possible combiantions they make. All the more the
recognition sequence also have degenerate bases. Is there anybody out there to
help me optimize the algorithm? Yes, there is. So thanking in advance to all
those who respond.
Ravi Gupta.
Research Scholar
DA University, M.P., India.

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