From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: Barry Barker <beb@dmu.ac.uk>
Subject: [Q] WISDOM Database
Message-ID: <1995Feb3.181747.12488@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 1 Feb 1995 12:25:46 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 5

Is there such a database for Biomed information, if so where?Can you help?  Thank you for your time and trouble.
i
Sent by: the WWW suggestion program @EMBnet Switzerland (info@ch.embnet.org)
Signed: Barry Barker <beb@dmu.ac.uk> 
Date:   Feb 1 1995 at 12:25:46 GMT.

From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: 5015920@mcimail.com
Subject: WWW Job Opening for Nature
Message-ID: <1995Feb3.175544.11817@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 1 Feb 1995 06:36:09 GMT
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[note from the moderator: We imply non-profit means non-commercial]

Attention!  The Nature Conservancy, a non-profit conservation group dedicated 
to preserving the world's dwindling biological diversity with offices across 
the U.S. and partner organizations in Canada and Latin America seeks a 
"Webmaster" for an immediate opening.  The position will initially build a Web 
server with pages for 60 biodiversity monitoring programs -- known as the 
Natural Heritage Network.  Ultimately, this Web server will be the top level of 
a series of "hot-linked" Natural Heritage Network Web servers that will be 
distributed across the Western Hemisphere.  

Sound interesting?  I also have an immediate opening for a Unix-TCP/IP 
specialist as well to help these distributed programs with overall 
connectivity.  Put your skills to work preserving Nature.

Dave Meyer
The Nature Conservancy
5015920@mcimail.com




From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Jeff Matthews <mookie@physics.ubc.ca>
Subject: New Radiation Biology Web Site
Message-ID: <1995Feb3.173454.11488@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 2 Feb 1995 22:29:40 GMT
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Lines: 9

There's a new WWW site dedicated to Radiation Biology. Point your web browser to

http://www.science.ubc.ca/departments/physics/radbio/HomePage.html

THere's current journal contents, a job board, conference listings and 
monthly editorials. There's also a list of e-mail adresses of other 
radiation biologists. Come in, take a look around, sign the guest book
and let us know what you think!


From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Mike Cherry <cherry@genome.Stanford.EDU>
Subject: Saccharomyces Genome Database
Message-ID: <1995Feb3.180646.12222@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
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Approved: bio-www@comp.bioz.unibas.ch
Lines: 34

Saccharomyces Genomic Information Resource

        http://genome-www.stanford.edu/

    This WWW server provides access to the yeast database called
SacchDB built using the ACEDB software (Durbin, Sanger Centre and
Thierry-Mieg, CNRS Montpellier). The ACEDB/WWW gateway (Decoux,
Moulon) is used to provide the WWW access.  The results of the
international effort to sequence the S.  cerevisiae genome, edition 12
of the Mortimer genetic maps, the Olson physical map, links to other
yeast information, documentation on using ACEDB databases, index of
the BioSci Yeast conference and more is available from the above URL.

    SacchDB for Macintosh (680X0 and PPC) and several flavors of UNIX
is available from either:

        ftp://genome-ftp.stanford.edu/pub/yeast/SacchDB
        ftp://ncbi.nlm.nih.gov/repository/SacchDB

    A WAIS index of the information contained in SacchDB, index of
BioSci Yeast conference, as well as images and tables derived from the
database, and more, are available from:

        gopher://genome-gopher.stanford.edu/11/Saccharomyces

    These yeast resources are provided by the Saccharomyces Genome
Database project at Stanford University through a grant from the
National Center for Human Genome Research, National Institutes of
Health, USA.

J. Michael Cherry                       Internet: cherry@genome.stanford.edu
Stanford DNA Sequence & Tech. Center    Saccharomyces Genome Database
Stanford University School of Medicine  Stanford, California  94305-5120
Voice: 415-723-7541                     FAX: 415-723-7016

From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Adam Bernstein
Subject: FAQ Transparent/Interlaced GIF seekers READ ME
Message-ID: <1995Feb3.183415.13139@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
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[ Article crossposted from comp.infosystems.www.announce ]
[ Posted on 30 Jan 1995 16:43:16 -0800 ]

[NOTE: This document is also available on the World-Wide Web at
<URL:http://dragon.jpl.nasa.gov/~adam/transparent.html>.]


Before you ask about transparentizing and interlacing GIF's, please 
point yourself at the WWW FAQ, which covers these topics in Section 
5.7.7.  The URL is:

	<URL:http://sunsite.unc.edu/boutell/faq/www_faq.html>

Come to think of it, I'm guessing that info is also contained in FAQs
for the graphics newsgroups, but this one I know for sure.  The advantage
to this one is that it has hyperlinks to all the relevant pages and 
tools for the various platforms.  

Where, you may ask, could you get any other FAQs, if you so desired?  You 
could try FTP to:

	<URL:ftp://rtfm.mit.edu/pub/usenet-by-hierarchy>
	<URL:ftp://grasp.insa-lyon.fr/pub/faq-by-newsgroup>

which contain archives by newsgroup of every FAQ there is (I think).
Pretty impressive, no?  For heaven's sake, don't overload them.  

The WWW FAQ leaves out one worthy item:  In Windows, the program LviewPro 1A
can save GIFs as interlaced and as GIF89a format with the background color
transparent (and it's a full-featured graphics manipulation program).  
Check it out at your favorite SIMTEL mirror FTP site:

	<URL:ftp://oak.oakland.edu/SimTel/msdos>
	<URL:ftp://wuarchive.wustl.edu/systems/ibmpc/msdos>
	<URL:ftp://archive.orst.edu/pub/mirrors/simtel/msdos>

Also for Windows (or DOS), I highly recommend Alchemy Mindworks' Graphics 
Workshop, though I can't recall if it does transparent/interlaced stuff or 
not.  They have a new program called GIF Construction Set for Windows, which
does do transparent (though the docs don't mention interlaced, so I don't
know about that).  Their URL is:

	<URL:http://uunorth.north.net:8000/alchemy/html/alchemy.html>

And finally, you all might want to check out the Graphics Archive Web site,
which is muy bueno for all kinds of graphics stuff:

	<URL:http://www.best.com/~bryanw/index.html>

I'm going to post this regularly for a while, unless screaming hordes
of enraged net surfers bombard my mailbox with "Stop posting that transparent/
interlaced GIF crap, you dweeb" messages, and then only if the number of 
said messages exceeds the number of people posting to request info on
transparent and interlaced GIFs.  The only reason I'm doing this is because
the regular postings of the FAQ don't seem to be frequent enough to cut
down on this AMFAQ (Apparently Most FAQ). 

	Thank you, and good night.


Adam Bernstein                           Jet Propulsion Lab
Avionic Equipment Section,               MS 198-235
  Optical Tracking Group                 4800 Oak Grove Dr.
http://dragon.jpl.nasa.gov/~adam/        Pasadena, CA 91109
adam@dragon.jpl.nasa.gov                 Phone: 818 354-9784
  or adam.c.bernstein@jpl.nasa.gov       FAX:   818 393-6105

From owner-www@net.bio.net Thu Feb 02 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Lincoln Stein
Subject: MIT CGR HUMAN PHYSICAL MAPPING DATA RELEASE 4
Message-ID: <1995Feb3.183503.13208@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 1 Feb 1995 16:35:36 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 80

[ Article crossposted from bionet.genome.chromosomes,bionet.announce ]
[ Posted on 31 Jan 1995 15:13:37 -0800 ]

                         ANNOUNCING:
      WHITEHEAD INSTITUTE/MIT CENTER FOR GENOME RESEARCH
               HUMAN GENOMIC MAPPING PROJECT 
                 DATA RELEASE 4 (JANUARY 1995)


The fourth release of data from the Human Physical Mapping
Project at the Whitehead Institute/MIT Genome Center, covering data
generated through the end of January, 1995, is now available.

This data release contains YAC screening data for 5525 sequence
tagged sites (STSs) screened on the CEPH mega-YAC library.  For 
each STS, we report addresses for the YACs
found to contain the STS. From the data obtained so far, there are
over 900 contigs assembled using double linkage between STSs. 

The data is available electronically in two ways.  

ANONYMOUS FTP: The entire data release is available as a set of
Microsoft Excel files and tab-delimited ascii files on our ftp
server.  Using an ftp client (such as "Fetch" on the Macintosh),
connect to "ftp-genome.wi.mit.edu".  Use "anonymous" as your user name,
and give your e-mail address as your password.  The data files are
present in the directory /distribution/human_STS_releases/july94. 
The contents are as follows:

  01-95.INTRO.mswd - Description of the data release, Macintosh format.
  01-95.INTRO.txt - The same as ascii text
  01-95.STS.YAC.sea.hqx - STS & YAC screening data, in MS-Excel format.
  01-95.STS.YAC.txt - The same as tab-delimited text.
  01-95.sequence    - Full sequences of previously unpublished STSs.

THE WORLD-WIDE WEB: You will need a World Wide Web client such as
Mosaic (Unix, MS-Windows and Macintosh) or MacWeb (Macintosh). 
Instruct your client to connect to "http://www-genome.wi.mit.edu/". 
>From there, follow the "Human Physical Mapping Project" link.  You will be
able to browse and download the raw data set as well as to view
doubly-linked contigs.

A subset of the STSs (those for which we have chromosomal assignments)
are also available through the Genome Database (GDB).

QUESTIONS AND PROBLEMS.  If users have any questions or problems,
please contact us at human_STS_help@genome.wi.mit.edu We invite
suggestions about how to make these data release most useful.

DATA RELEASE POLICY AND CITATION.  Data releases are scheduled every
90 days.  At the end of each calendar quarter, all genomic mapping
data are reviewed and prepared for distribution via CGR's electronic
databases.  Data releases typically occur within two weeks of the
close of the quarter (i.e., in mid-January, mid-April, mid-July and
mid-October).  Releases are announced by electronic messages posted
to the following two newsgroups: "bionet.genome.chromosomes" and
"bionet.announce". 

CGR's data release policy aims to ensure that scientific colleagues
have immediate access to information that may assist them in the
search for genes. Data releases do not constitute scientific
publication of CGR's work, but rather provide scientists with a
regular look into our lab notebooks.   For projects aimed at the
analysis of particular genes or subchromosomal regions, permission is
hereby granted to use our data without the need for a formal
collaboration, subject only to appropriate acknowledgment.   For
projects aimed at large-scale mapping of entire chromosomes or entire
genomes, use of the data and markers should be on a collaborative
basis.

 The information for the human genome mapping project should be cited
as: Whitehead Institute/MIT Center for Genome Research, Human Physical
Mapping Project, Data Release 4 (January 1995).


-- 
========================================================================
Lincoln D. Stein                Whitehead Institute/MIT Genome Center
lstein@genome.wi.mit.edu	Cambridge, MA 02142
========================================================================

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!agate!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: "M. Kelly" <mkelly@hgmp.mrc.ac.uk>
Subject: MBx on the World Wide Web
Message-ID: <1995Feb13.082246.17171@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Tue, 7 Feb 1995 00:22:51 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 38


MBx on the World Wide Web

The European Collaborative Interspecific Backcross (EUCIB) provides
the resources for the high resolution genetic  mapping of the 
mouse genome. One of the primary aims is to construct a high resolution 
microsatellite map of all available simple sequence length polymorphisms 
across the entire mouse genome. The MBx database supports the mapping
effort. The database was constructed using distributed client/server
database - Sybase, Sybase application development tools (APT), the C and 
XView programming languages. MBx stores all locus, probe and SSLP data. 
Allele data at each locus is presented as a scrollable matrix on screen. 
MBx can compute genetic linkage between loci and in addition, can 
automatically perform the necessary haplotype analysis by minimising the
number of observed recombinants across any chromosome region in order
to derive genetic order of loci. Furthermore MBx can abstract all mice 
carrying recombinants in any chromosome region. Such information when 
downloaded to  robots is imported for the automated and error free selection
of correct DNA's for subsequent high resolution microsatellite mapping in a 
particular chromosome region.

To date the latest  EUCIB maps and mapping data, including ACeDB type 
Multimaps have been available via the UK HGMP Resource Centre Computing Menu.

MBx is accessed from the HGMP menu by typing 'mbx' at the menu prompt.
EUCIB genetic maps in "Encylopedia of the Mouse Genetic Map" format, and 
MBx-ACeDB Multimaps which compare MBx and MIT genetic data are available.

In addition MBx is now available on the World Wide Web.

http://www.hgmp.mrc.ac.uk/local-data/mbx/Mbx_Homepage.html

The following items are available via World Wide Web:
 -pedigree information from the EUCIB backcross,
 -probe and locus information,
 -haplotype panels,
 -genetic maps EotM format,
 -information on accessing the EUCIB User Service.

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: Keith Robison <robison@nucleus.harvard.edu>
Subject: Attention Web Masters: The Top of the Web has moved
Message-ID: <1995Feb13.071743.16166@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 8 Feb 1995 00:19:40 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 29

Just to publicize something which hasn't been publicized much.  

CERN is handing over the World Wide Web project to the W3 organization,
which will continue to develop the project.  As such, most hyperlinks
that reference CERN should switch over to referencing W3

So, change all your references to

	http://info.cern.ch/...

to
	http://www.w3.org/...


(of course, it wouldn't hurt to check the new addresses :-)

At the current time, automatic redirects are actually moving you to
www.w3.org whenever you try to reach info.cern.ch, but some time
later this year info.cern.ch will quit doing this.


Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison@mito.harvard.edu 



From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: WebSub <websub@ncgr.org>
Subject: WebSub: New DNA Sequence Submission Method
Message-ID: <1995Feb13.065713.15659@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Sat, 4 Feb 1995 04:15:56 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 58


-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
=-=-=-=-       The Genome Sequence Data Base at the       -=-=-=-=-
=-=-=-=-  National Center for Genome Resources Announces  -=-=-=-=-
=-=-=-=-   WebSub: A New DNA Sequence Submission Method   -=-=-=-=-
-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-

The Genome Sequence Data Base is pleased to announce the beta version
of WebSub -- a new means of submission for your nucleotide sequence
data. In response to many requests, GSDB has developed a World Wide Web
(WWW) submission form.  The convenience of the traditional submission
form is now available on-line for use with your Macintosh, PC or Sun.
Much like the ASCII text form, this is a simple fill-in-the-blank form
which is submitted with the click of a button.  This form eliminates
the need for the use of additional applications such as email, text
editors or Authorin(tm).

WebSub produces automatically-processable submissions like those
created by Authorin, and thus they should be usable by all of the
nucleotide sequence databases. However, during the beta test phase, all
submissions prepared with WebSub will be processed by GSDB and the
results will be immediately forwarded on to the other databases (DDBJ,
EMBL, and NCBI) for inclusion in their data collections.

The URL to directly access WebSub on the World Wide Web (WWW) is:

      http://www.ncgr.org/gsdb/WebSub.html

If you do not currently have access to a Web browser that supports
forms, please do not hesitate to contact us. We will be happy to direct
you to ftp sites from which you may download these applications.  Please
note that the following browsers have been found to be compatible with
this tool and are therefore recommended. 

      Sun Users            -- Mosaic & Netscape 
      Mac Users            -- Netscape 
      IBM/compatible Users -- Netscape

At this time, WebSub is known not to work with Mosaic on either the Mac
or IBM PC; but WebSub does work with Netscape on these platforms.

In addition, should you already have access to the World Wide Web, the
GSDB server (http://www.ncgr.org/gsdb) offers a wide range of services,
such as data retrieval, tailored query capability, submission status
information, software and documentation, as well as on-line updates
(http://www.ncgr.org/gsdb/update.html).

Due to restrictions in current WWW browsers there are some limitations
on the amount of data that can be submitted with WebSub (e.g., 31k
basepairs of sequence and ten features). However, these limitations
will not present a problem for the majority of submissions. For more
information see the submission overview page on our WWW server.

We thank you for your time and we look forward to receiving your data
and your comments through WebSub. If you have not received an
acknowledgment of your submission within one working day or need any
other assistance, please contact us at WebSub@gsdb.ncgr.org or
505/982-7840.

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!bloom-beacon.mit.edu!usc!cs.utexas.edu!swrinde!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: Keith Robison <robison@nucleus.harvard.edu>
Subject: WWW VL Biosciences Update
Message-ID: <1995Feb13.072549.16285@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 8 Feb 1995 17:53:35 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 44

Recent additions to the WWW Virtual Library Biosciences:

Developmental Biology
        http://golgi.harvard.edu/biopages/develop.html
Immunology
        http://golgi.harvard.edu/biopages/immuno.html

Mycology
        http://muse.bio.cornell.edu/taxonomy/fungi.html
        Kathy Hodge
        KH11@cornell.edu

Caenorhabditis elegans
        http://eatworms.swmed.edu/VLhome.html
        Leon Avery
        leon@eatworms.swmed.edu

Drosophila
        http://www-leland.stanford.edu/~ger/drosophila.html
        Gerard Manning
        ger@leland.stanford.edu

Pharmacy (Medicine)
        http://www.cpb.uokhsc.edu/pharmacy/pharmint.html
        David Bourne
        david-bourne@uokhsc.edu

Yeasts
        http://genome-www.stanford.edu/VL-yeast.html
        Mike Cherry
        cherry@genome.stanford.edu



Also, the WWW VL Genetics has moved

Genetics
        http://www-bprc.mps.ohio-state.edu/cgi-bin/hpp?genetics.html
        Ray Grimalia
        mcb42@unicorn.bwco.com


Keith R.
Biosciences Coordinator

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Shun'ichi Kuroda <skuroda@inherit.biosig.kobe-u.ac.jp>
Subject: [repost] [Q] Promoter Sequence Analysis
Message-ID: <1995Feb13.160849.25030@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 9 Feb 1995 07:08:35 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 30

Dear Sirs:

I am an assistant professor of Kobe university.  
Before the severve earthquake on Jan 17, I posted same question 
to this NG.  But the RESs for my question could not be arrived at 
our server, since the server was broken by the earthquake.
So I repost the same question.

(Question)
I have a novel promoter sequence from human genome, of which 
length is about 2kbp and has enough transcriptional activity.  
However, it has been still unclear whether the promoter sequence 
contains known promoter motifs or not.  
If the database of the known promoter motifs is available, it will 
be helpful for us to construct the deletion mutants and understand 
the essential transcriptional region of the promoter sequence.
Therefore, I want to know the services for analyzing the promoter
sequence, which are on internet or distributed as commercial 
softwares. 
 Any comments will be appreciated.
Many thanks,

-- 
SHUN'ICHI KURODA
BIOSIGNAL RES CENTER
KOBE UNIVERSITY
NADA, KOBE, 657 JAPAN
E-mail: skuroda@inherit.biosig.kobe-u.ac.jp
URL:http://inherit.biosig.kobe-u.ac.jp/biosighome.html
Tel +81-78-803-1255   Fax +81-78-803-0994

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: "Victor V. Solovyev" <solovyev@cmb.bcm.tmc.edu>
Subject: Exon-exon junctions in cDNA by BCM Gene-finder
Message-ID: <1995Feb13.154533.24483@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Fri, 10 Feb 1995 19:45:32 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 38

New program:
*************************************************************************
	RNASPL - Prediction of exon-exon junction positions in
		 cDNA sequences
 	Department of Cell Biology, Baylor College of Medicine
=========================================================================
	Analysis of human cDNA sequences is available through 

 WWW BCM Human Genome Center and Search launcher Home page
URL:http://kiwi.imgen.bcm.tmc.edu:8088/search-launcher/launcher.html

for accsess to Gene-finder prediction Help files and programs.
->  BCM Gene Finder

Description:
**********************
   Recognition of exon-exon junctions in cDNA may be very useful for 
gene sequencing when starting with a sequence of cDNA clone. In a given 
cDNA sequence we need to select sites for PCR primers that (hopefully) 
lie in adjacent exons. 
   Prediction is performed by linear discriminant function combining 
characteristics describing  tipical sequences around exon-exon junctions.

  The method is described in 
  Solovyev V.V.,Salamov A.A., Lawrence C.B.
   Predicting internal exons by oligonucleotide composition and 
   discriminant analysis of spliceable open reading frames. 
  (Nucl.Acids Res.,1994, 22,24, 5156-5163).

Accuracy:
********************************
We can not predict exon-exon junction position with very high accuracy,
because some information was lost after splicing. We predict positions
marked by '*', where 75% of potential exon-exon junctions are localized. 
Additionally, we mark '-' positions where exon-exon junctions absent with
probability about 90%.
   We recommend to select primer sequences in continuous '-' regions,
that do not cross '*' or ' ' positions.

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Wilfried Janning
Subject: FlyView - A Drosophila Image Database
Message-ID: <1995Feb13.163508.25593@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Mon, 13 Feb 1995 16:07:58 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 21

[ Article crossposted from bionet.drosophila ]
[ Posted on 9 Feb 1995 17:05:03 GMT ]

Dear Drosophilists,

we are starting to construct an image database on Drosophila development and
genetics, especially on expression patterns of genes (enhancer trap lines, cloned 
genes). Our aim is to establish the possibilty to compare images on the computer 
screen or to search for special patterns at different developmental stages. Therefore, 
all images are accompanied by text descriptions that can be used to search with 
keywords.

You may be interested to try the experimental version of FlyView.  It is available on 
World Wide Web, URL is http://pbio07.uni-muenster.de/

Please send any comments, suggestions or problems to
janning@vnwz00.uni-muenster.de

Best regards,

Wilfried Janning

From owner-www@net.bio.net Sun Feb 12 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Michael A. Chipperfield
Subject: Genome Project
Message-ID: <1995Feb13.164453.25759@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Mon, 13 Feb 1995 16:15:18 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 34

[ Article crossposted from bionet.molbio.genome-program ]
[ Posted on Sat, 4 Feb 1995 22:27:25 GMT ]

[Answer to a question 'what is the Human Genome Project' ? ]
Jon,

There is an excellent WWW site maintained by the Department of Energy, which
outlines the goals for the Human Genome Program, and provides as well a primer
on the basic science of the project. The URL for this site is:

      http://www.er.doe.gov/production/oher/hug_top.html

Hope this helps!

Sincerely,

Michael A. Chipperfield
DNA Data Coordinator
Genome Data Base

In article <3grkcq$80l@maze.dpo.uab.edu>, Mpsy0l3@uabdpo.uab.edu (Flames) wrote:

> Could Someone PLEASE TELL ME EXACTLY WHAT THIS PROGRAM IS?!?!!?!?
> Thank You very much. I have to write a paper on it, so anything you could 
> give me would be VERY appreciated.
> 
> THANKS!!!
> 
> Jon, University of Alabama.






From owner-www@net.bio.net Thu Feb 16 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Keith Robison <robison@golgi.harvard.edu>
Subject: NCSA HTTPD 1.3 Security Problem
Message-ID: <1995Feb17.180837.16558@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 16 Feb 1995 14:39:28 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 89

For those webmasters who haven't seen it yet, there is a security hole
in NCSA HTTPD 1.3 which can apparently be exploited by an automated
script.  NCSA has not yet provided fixed source or binaries, but
the CIAC folks recommend a simple fix in the source.  I have recompiled
NCSA httpd 1.3 for SunOS 4.x using gcc, and this binary is available 
via anonymous FTP

	ftp://golgi.harvard.edu/pub/robison/httpd


Replace your existing httpd binary with this one and restart the server.


CIAC advisory attached.


Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison@mito.harvard.edu 


>             _____________________________________________________
>                        The U.S. Department of Energy
>                     Computer Incident Advisory Capability
>                            ___  __ __    _     ___
>                           /       |     /_\   /
>                           \___  __|__  /   \  \___
>             _____________________________________________________

>                                ADVISORY NOTICE

>                         Unix NCSA httpd Vulnerability

> February 14, 1995 1030 PST                                        Number F-11
> _____________________________________________________________________________

> PROBLEM:       A vulnerability has been discovered in the NCSA WWW server
>                software (httpd).
> PLATFORMS:     Unix systems running NCSA httpd version 1.3.
> DAMAGE:        Remote users may gain unauthorized access.
> SOLUTION:      Implement workaround as described below.
> _____________________________________________________________________________

> VULNERABILITY  This vulnerability, along with an automated exploitation
> ASSESSMENT:    script, has been announced in public forums on the Internet.
>                CIAC recommends that sites install the workaround on affected 
>                systems as soon as possible.
> _____________________________________________________________________________

>           Critical Information about the NCSA httpd Vulnerability

> CIAC has learned of a serious vulnerability in the NCSA WWW server software,
> httpd.  By sending a carefully constructed request to the WWW server, an
> intruder can cause an internal buffer overflow and push arbitrary 
> instructions onto the program stack.  These new instructions may allow the
> intruder unauthorized access to the WWW server.

> Until official patches are available from NCSA, CIAC recommends the following
> temporary fix be installed.  In the file httpd.h, change the string length
> definitions from:

>       /* The default string lengths */
>       #define MAX_STRING_LEN 256
>       #define HUGE_STRING_LEN 8192

> to:

>       /* The default string lengths */
>       #define HUGE_STRING_LEN 8192
>       #define MAX_STRING_LEN  HUGE_STRING_LEN

> Then rebuild, install, and restart the new httpd server.

> It is likely that these attacks will generate unusual server log entries.  
> The httpd access_log file should be examined for unusual requests, especially
> those containing control characters.

> Note that while this workaround addresses the vulnerability currently being
> exploited, there are likely to be other similar vulnerabilities present in
> this and other WWW server software.  To lessen the chance of compromise, it
> is strongly recommended that WWW servers run as unprivileged users (e.g.
> user "nobody") and that they be locked into a restricted filesystem via the
> chroot() system call.  For more information, please see CIAC Document 2308, 
> "Securing Internet Information Servers," which is available via anonymous
> FTP from ciac.llnl.gov in the directory /pub/ciac/ciacdocs/.


From owner-www@net.bio.net Thu Feb 16 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Georg Fuellen <fuellen@techfak.uni-bielefeld.de>
Subject: [Q] WWW / Internet Resources for Multiple Alignment !?
Message-ID: <1995Feb17.174928.16087@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 16 Feb 1995 18:02:02 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 65

Dear All,
I'd like to complete the following list of Internet Resources for 
Multiple Alignment. It will be used for a Biocomputing Course offered
for free, as described at the end of this message.
I will post a summary if I'm pointed to other resources.

PLEASE REPORT ANY USEFUL RESOURCES THAT ARE NOT ON THIS LIST !!!!!
PLEASE REPORT ANY USEFUL RESOURCES THAT ARE NOT ON THIS LIST !!!!!
(sorry for shouting, but I'd really like to get a few responses :-)

http://geoff.biop.ox.ac.uk/servers/amas_server.html
AMAS - Analyse Multiply Aligned Sequences

http://ibc.wustl.edu/msa.html
MSA, Calcutating Multiple Alignments.

http://cbrg.inf.ethz.ch/subsection3_1_1.html#SECTION0001100000000000000
AllAll: Calculate Phylogenetic Trees, Alignments and a lot more

http://geoff.biop.ox.ac.uk/papers/rev93_1/rev93_1.html
Protein Sequence Alignment and Database Scanning, by Geoffrey Barton

gopher://s-crim1.dl.ac.uk/00/EMBnet%20Bioinformation%20Resource%20UK/Data%20%26%
20Software/databases/3d_ali/3d_ali.doc
3D-Ali Information File

http://www.embl-heidelberg.de/srs/srsc?-info||ALI
3D-ALI Database Interface

http://www.embl-heidelberg.de/predictprotein/predictprotein.html
The PredictProtein server, utilizing MaxHom Alignments
(Are MaxHom Alignments offered anywhere ??)

http://www.blocks.fhcrc.org/
Detection and verification of protein sequence homology : BLOCKS WWW Server


Thanks a lot for any hints !

***************************************************************************
Also, I'd like to ask whether the following resources are available 
somewhere on the net:

1. The ATLAS interface to sequence data, by which you can retrieve
   a sequence using a suitable subsequence of only a few amino acids.

2. McClure's Multiple Alignment Data (they are supposed to be at
   ftp.embl-heidelberg.de, according to the EMBL File Server News, Number 11,
   but I could not find them).

3. Kececioglu's maximum weight trace data, Reference:
   J. D. Kececioglu, The maximum weight trace problem in multiple sequence
   alignment. In Proc. of the 4th Symp. on Comb. Pattern Matching, LNCS 684,
   pp. 106-119 (1993)
***************************************************************************

best wishes,
  georg
fuellen@dali.Mathematik.Uni-Bielefeld.DE, fuellen@MIT.EDU
  http://www.techfak.uni-bielefeld.de/techfak/persons/fuellen/georgF.html
For info about a free online Biocomputing Course, to be offered in Summer 1995
under the auspices of GNA-VSNS, please point your WWW/hypertext browser to
http://www.techfak.uni-bielefeld.de/techfak/persons/fuellen/BCDhome.html
Please visit this page before inquiring about the course !


From owner-www@net.bio.net Thu Feb 16 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Jason Brinck <J.D.Brinck@bham.ac.uk>
Subject: [Q] Pseudomonas information
Message-ID: <1995Feb17.172304.15244@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 16 Feb 1995 17:48:36 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 8

Does anyone know of any Pseudomonas WWW pages / databases out there? Anything 
on P.putida would be even better!

Thanks in advance,

Jason Brinck,
School of Biochemistry,
University of Birmingham, UK

From owner-www@net.bio.net Thu Feb 16 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!news.sprintlink.net!pipex!sunsite.doc.ic.ac.uk!daresbury!bioftp.unibas.ch!moderate
From: Pedro M Coutinho <pedro@iastate.edu>
Subject: Re: [repost] [Q] Promoter Sequence Analysis
Message-ID: <1995Feb17.140924.9687@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 16 Feb 1995 20:52:15 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 51


Hi!

In article <1995Feb13.160849.25030@comp.bioz.unibas.ch>, Shun'ichi Kuroda <skuroda@inherit.biosig.kobe-u.ac.jp> writes:
|> Dear Sirs:
|> 
|> I have a novel promoter sequence from human genome, of which 
|> length is about 2kbp and has enough transcriptional activity.  
|> However, it has been still unclear whether the promoter sequence 
|> contains known promoter motifs or not.  
|> If the database of the known promoter motifs is available, it will 
|> be helpful for us to construct the deletion mutants and understand 
|> the essential transcriptional region of the promoter sequence.
|> Therefore, I want to know the services for analyzing the promoter
|> sequence, which are on internet or distributed as commercial 
|> softwares. 
|>  Any comments will be appreciated.
|> Many thanks,
|> 
|> -- 
|> SHUN'ICHI KURODA
|> BIOSIGNAL RES CENTER
|> KOBE UNIVERSITY
|> NADA, KOBE, 657 JAPAN
|> E-mail: skuroda@inherit.biosig.kobe-u.ac.jp
|> URL:http://inherit.biosig.kobe-u.ac.jp/biosighome.html
|> Tel +81-78-803-1255   Fax +81-78-803-0994

You might find something useful in the following URLs, especially in PSORT.

EPD - Eucaryotic Promoter Database at EMBL-Heidelberg 
 http://www.embl-heidelberg.de/srs/srsc?-id||781260221_129.186.4.14||-info||EPD

PSORT - Predict Protein Sorting Signals Coded in Amino Acid Sequences at GenomeNet, Japan
 http://psort.nibb.ac.jp/

Good Luck!

Pedro Coutinho

--------------------------------- H2N-CH-CO-NH-CH-CO-...-NH-CH-COOH --
Pedro M. Coutinho  - Graduate Student  \        \            \        
IOWA STATE UNIVERSITY                   R1       R2           Rn      
Department of Chemical Engineering               Phone: 1-515-294-9370
2114 Sweeney Hall                                Fax:   1-515-294-2689
Ames, IA 50011-2230                          E-mail: pedro@iastate.edu
U.S.A.                      URL: http://www.public.iastate.edu/~pedro/
----------------------------------------------------------------------
-- 
Pedro M Coutinho
pedro@iastate.edu

From owner-www@net.bio.net Thu Feb 16 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Ole Matzura <ole@mango.mef.ki.se>
Subject: Introducing RNAdraw!
Message-ID: <1995Feb17.174312.15789@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Fri, 17 Feb 1995 13:17:02 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 18

    [The following text is in the "iso-8859-1" character set]
    [Your display is set for the "US-ASCII" character set]
    [Some characters may be displayed incorrectly]

Hello Everybody!


  A new RNA structure program for Windows (3.1/NT/95) has 
seen the light! Please take a look at:


      http://broccoli.mfn.ki.se/rnadraw/rnadraw.html

Thank you, have a nice weekend!

   Ole Matzura

     (ole@mango.mef.ki.se)

From owner-www@net.bio.net Sun Feb 19 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: "Martin D. Leach" <leach@bu.edu>
Subject: Re: [Q] WWW / Internet Resources for Multiple Alignment !?
Message-ID: <1995Feb20.162149.9444@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Fri, 17 Feb 1995 21:12:41 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 36

check out

http://kiwi.imgen.bcm.tmc.edu:8088/search-launcher/launcher.html


BCM Search Launcher

The purpose of BCM Search Launcher is to organize molecular
biology-related search and analysis
services available on the WWW by function, and to provide a single
point-of-entry for related
searches (e.g., a single page for launching protein sequence searches
using standard parameters). 
       Please send suggestions for additions to these pages to:
www@mbcr.bcm.tmc.edu


good luck


ciao Martin

-- 
.....          Martin Leach                Email:leach@bu.edu 
   _|____      Dept. of Pharmacology       Phone: (617) 638-5323        
   / o  /      Boston Univ. School of Med. Fax:   (617) 638-4329         
 _/  |-/__==/  80 E. Concord St. (L603)
(BULLDOZER) \_ Boston MA 02118            "Not the old underpants 
               USA                                on your
                                             head.....WIBBLE"
My homepage: http://155.41.115.114/Leach.html
Biotech company listing: http://155.41.115.114/jumper/biolcomm.html

p.s. try BioMOO  -virtual biology on the internet..
telnet bioinfo.weizmann.ac.il 8888
 

From owner-www@net.bio.net Sun Feb 19 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Marc Colet <mcolet@ben.vub.ac.be>
Subject: WWW2GCG beta testers please...
Message-ID: <1995Feb20.160544.9201@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Fri, 17 Feb 1995 17:12:38 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 31

Announcing beta test phase for WWW2GCG

This is to announce the beta release of WWW2CGC, a set of software
elements to run the WWW interface to access the GCG sequence analysis
software package.

We are looking for voluntary GCG managers who would be willing to install
the software, and come up with recommendations/criticisms for further
improvements. Initial installation was on an OSF/1 DEC AXP machine. A
successful port to a Dec MIPS ULTRIX (5000/200) workstation could be done
with minor efforts.

Several conditions must be met in order to install the software :

- a UNIX computer on which GCG version 8 is installed and running

- the right to recompile the GCG package, after some minor change

(In our hands, the slight adaptation to the GCG software had no detectable
effect whatsoever on the way GCG itself is running...)

- the right of super-user for some of the installation operations

- some disc space to install the whole bunch of files, including an httpd
server. This must be an independent server from any other eventually already
running on the same computer. A total of about 10 megabyte seems adequate.

Please send a email to rwww@dbmdec5.ulb.ac.be to receive the informations
about how/where to get hold of a copy of the package.

Marc Colet (mcolet@ulb.ac.be)

From owner-www@net.bio.net Thu Feb 23 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Roy Goodacre <rrg@aber.ac.uk>
Subject: Announcing a WWW neural networks in (micro)biology page
Message-ID: <1995Feb24.065702.6903@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Wed, 22 Feb 1995 07:04:07 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 30

Dear All,

This is to announce that a new WWW site (or at least a very large update)
about our applications of neural networks within microbiology and biology can 
be found at the following addresses:

A CHEMOMETRICS HOME PAGE
	http://gepasi.dbs.aber.ac.uk/roy/chemom.htm  

PYROLYSIS MASS SPECTROMETRY HOME PAGE
	http://gepasi.dbs.aber.ac.uk/roy/pymshome.htm   

MY CV WHICH GIVES LINKS TO ABOVE
	http://gepasi.dbs.aber.ac.uk/roy/rgcv.htm

The sort of things found here deal with:
	1. The use of supervised and unsupervised learning.
	2. What pyrolysis mass spectrometry is.
	3. The identification and classification of bacteria.
	4. The quantification of biological systems (eg fermentor broths).
	5. The adulteration of food stuffs.


Any sensible comments would be gratefully received.

Dr Roy Goodacre            E-mail: rrg@aber.ac.uk
FTP:   144.124.112.36      Voice:  +44 970 623111 ext 4187 (work)
Fax:   +44 970 622354              +44 974 241236 (home)
URL:   http://gepasi.dbs.aber.ac.uk/roy/rgcv.htm
Snail: Inst Biol Sci, University of Wales, Aberystwyth, Dyfed, UK

From owner-www@net.bio.net Thu Feb 23 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: yichena@ifi.uio.no
Subject: [Q] Read data from client site
Message-ID: <1995Feb24.075945.8726@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Thu, 23 Feb 1995 10:49:21 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 13

Hi,

How is it implemented or has this been implemented if a WWW server simply
reads in long sequence data then does some computation on it and send the
results back to the clients?

I know one way is to use FORM/POST with input type of TEXTAREA. and you
may expect your clients to understand copy-paste. However, is it possible to
open the file on client sites and read in ?

Any reply will be appreciated, and please E-mail me!

Yicheng

From owner-www@net.bio.net Sun Feb 26 22:00:00 1995
Newsgroups: bionet.software.www
Path: biosci!daresbury!bioftp.unibas.ch!moderate
From: Jean Thioulouse <Jean.Thioulouse@biomserv.univ-lyon1.fr>
Subject: WWW online multivariate analysis service
Message-ID: <1995Feb27.071705.24825@comp.bioz.unibas.ch>
Sender: moderate@comp.bioz.unibas.ch (Bio-WWW moderator @ EMBnet Switzerland)
Organization: EMBnet Switzerland [Basel]
Date: Fri, 24 Feb 1995 17:10:29 GMT
Approved: bio-www@comp.bioz.unibas.ch
Lines: 12

NetMul is an online multivariate analysis WWW service. You can use
it to perform multivariate analyses (Principal Components Analysis,
Correspondence Analysis and Multiple Correspondence analysis) on
your data sets.

http://biomserv.univ-lyon1.fr/base.html

--
Jean Thioulouse - Laboratoire de Biometrie - Universite Lyon 1
69622 Villeurbanne CEDEX - France        Fax: (33) 78 89 27 19
    Try NetMul, a WWW online multivariate analysis system:
           http://biomserv.univ-lyon1.fr/base.html

