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From: BioCoRE <biocore@ks.uiuc.edu>
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JMV Molecular Viewer Support within BioCoRE

July 3, 2002:

Urbana, Illinois - The Theoretical Biophysics Group at the University of
Illinois is proud to announce an exciting new feature of BioCoRE, a
Biological Collaborative Research Environment. BioCoRE is freely
accessible at the Theoretical Biophysics Group website and development
is supported by the NIH National Center for Research Resources.

JMV <http://www.ks.uiuc.edu/Development/jmv/> version 1.0 can now be
accessed from within BioCoRE. JMV, a molecular viewer written using Java
and Java 3D, can be used to view molecular files stored within the
BioFS, BioCoRE's shared filesystem. JMV provides several molecular
representations, multiple coloring styles, lighting controls, and
stereoscopic rendering capabilities. Version 1.0 of JMV is currently
only available within BioCoRE, and a standalone release is upcoming.

In addition, several other BioCoRE components have seen key improvements
recently:

* The BioCoRE Control Panel can now be run as a standalone Java
application using Java Web Start. This frees users from the constraints
of running the Control Panel as a Java applet, which allows increased
flexibility and improved robustness since browser crashes no longer kill
the Control Panel.

* Improved overall "look and feel". The BioCoRE web pages no longer rely
on Javascript menus. This makes pages load faster and provides
compatibility with more browsers.

* Users can save JPEG files of states from VMD into BioCoRE
automatically. This allows researchers to browse states visually and
load desired configurations directly into VMD.

* You can now create Interactive accounts within Job Management.
Interactive accounts allow BioCoRE to submit jobs to any computer that
you can log into via SSH. This can be used to run jobs on machines that
BioCoRE doesn't officially support yet. (BioCoRE has built in support
for machines at PSC, NCSA and Globus sites using the Alliance
certificates)

* BioCoRE job management can now upload files to the remote
supercomputer center of your choice before submitting a job. This allows
researchers to keep their input files in the BioCoRE shared filesystem
and let BioCoRE automatically stage the files.


For details, please visit the BioCoRE website at
<http://www.ks.uiuc.edu/Research/biocore/>.

The Theoretical Biophysics group encourages BioCoRE users to be closely
involved in the development process through reporting bugs, contributing
fixes, periodical surveys and via other means. Questions or comments may
be directed to biocore@ks.uiuc.edu.

We are eager to hear from you, and thank you for using our software!




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To: bionet-software-www@net.bio.net
From: pirmail@NBRF.Georgetown.Edu (Pirmail)
Newsgroups: bionet.software.www
Subject: Announcing PIR-NREF: a comprehensive and non-redundant reference
 protein sequence database for full-scale or species-based protein
 identification
Organization: National Biomedical Research Foundation
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***********************************************************

ANNOUNCING PIR-NREF
Containing 968,861 non-redundant protein sequences

http://pir.georgetown.edu/pirwww/search/pirnref.shtml

***********************************************************


The Protein Information Resource (PIR) is pleased to announce the
release of NREF (Non-redundant REFerence) Protein Database at:

http://pir.georgetown.edu/pirwww/search/pirnref.shtml

The PIR-NREF provides a timely and comprehensive collection of all
protein sequence data from PIR-PSD, Swiss-Prot, TrEMBL, RefSeq, GenPept,

and PDB, with source attribution and minimal redundancy.  Identical
sequences from the same source organism (species) reported in different
databases are presented as a single NREF entry with protein IDs and
names from each underlying database, in addition to protein sequence,
taxonomy, and composite bibliography.

The web site provides direct entry retrieval (based on protein IDs).
text search (protein or species names), and sequence search (BLAST,
peptide match, and pattern match) for full-scale and species-based
protein identification.  Species-based browsing and searching are
supported for about 100 organisms, which includes over 70 complete
genomes.

The NREF is updated biweekly and available for free downloading and
redistribution in XML format (data file) and FASTA format (sequence
file) from our FTP site at:
ftp://nbrfa.georgetown.edu/pir_databases/nref/

Please contact Cathy Wu at pirmail@georgetown.edu with any comments or
suggestions.

The work is supported in part by NIH Grant# P41 LM05798


---


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From: pirmail@NBRF.Georgetown.Edu (Pirmail)
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Subject: Announcing iProClass Release 2.0: An integrated,
 value-added database of protein information
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***********************************************************

Announcing iProClass Release 2.0
An Integrated, Value-Added Database of Protein Information
Containing 809,717 Sequence Entries

http://pir.georgetown.edu/iproclass

***********************************************************


The Protein Information Resource (PIR) is pleased to announce release
2.0 of iProClass, an integrated resource for exploration of protein
information. The database provides comprehensive family relationships
and functional and structural features of proteins summarized from many
sources for all PIR-PSD, Swiss-Prot, and TrEMBL sequences, with rich
links to over 50 biological databases. The proteins are organized with
more than 36,000 superfamilies, 145,000 families, 3700 domains, 1300
motifs, and 550,000 FASTA similarity clusters. The cross-referenced
databases include:

- Protein Sequences: PIR-PSD, PIR-NREF, Swiss-Prot, TrEMBL, GenPept,
RefSeq
- Protein Families: Pfam, PROSITE, BLOCKS, COG, InterPro, MetaFam
- Genes and Genomes: GenBank, LocusLink, TIGR, SGD, GDB, OMIM, et al.
- Structures and Structural Classes: PDB, SCOP, CATH, PDBSum, MMDB, FSSP

- Enzymes and Pathways: EC-IUBMB, KEGG, WIT, BRENDA, MetaCyc
- Protein Interactions: DIP, BIND
- Post-Translational Modifications: RESID, Phosphorylation Site DB
- Protein Expressions/Proteomes: PMG
- Ontologies: GO
- Literature: PubMed
- Taxonomy: NCBI Taxonomy

iProClass is freely accessible for sequence searching or text retrieval
from more than 50 fields (see examples below). Both protein and
superfamily reports provide detailed descriptions with graphical domain
and motif display. Lists of proteins and superfamilies returned by
BLAST/SSEARCH search, peptide match, or text search are shown with
one-line summaries.

Protein Report:
   http://pir.georgetown.edu/cgi-bin/ipcEntry?id=A31997

Superfamily Report:
   http://pir.georgetown.edu/cgi-bin/ipcSF?id=SF000130

BLAST/SSEARCH Sequence Search Result (List):
   http://pir.georgetown.edu/iproclass/BLASTex.html

Peptide Match Result (List):
    http://pir.georgetown.edu/iproclass/PEPTIDEex.html

Text Search Result (List):
   http://pir.georgetown.edu/iproclass/TEXTex.html

To obtain a downloadable copy of iProClass or to establish reciprocal
links or mirror sites, please contact Cathy Wu at wuc@georgetown.edu.
Your comments and feedback are most welcome.

The work is supported in part by NSF grant# DBI-9974855 and NIH grant#
P41-LM05798.


---


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To: bionet-software-www@net.bio.net
From: softberry@softberry.com
Newsgroups: bionet.software.www
Subject: TSSP - Plant Promoter Identification program/ RegSite DB
Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre
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New TSSP program for Recognition of human Pol II promoter region 
         and start of transcription 

Method description: 
Algorithm predicts potential transcription start positions by linear 
discriminant 
function combining characteristics describing functional motifs and 
oligonucleotide 
composition of these sites. TSSP uses file with selected factor binding sites 
from RegSite DB (Plants) developed by Softberry Inc. using literature data.

 You can try TSSP at:
  
       http://www.softberry.com/berry.phtml?topic=promoter

TSSP output: 
First line - name of your sequence; 
Second and Third lines - LDF threshold and the length of presented sequence 
4th line - The number of predicted promoter regions 
Next lines - positions of predicted sites, their 'weights' and TATA box 
position 
 (if found) 
Position shows the first nucleotide of the transcript (TSS position) 
After that functional motifs are given for each predicted region; (+) or (-) 
 reflects the direct or complementary chain; S... means a particular motif 
 identificator from the Wingender data base. 

For example: 
tssp  Wed Jul 10 02:52:32 EDT 2002
>gi|1902902|dbj|AB001920.1| Oryza sativa (japonica cultivar-group) gene for phos
 Length of sequence-      5871
 Thresholds for TATA+ promoters -  0.02, for TATA-/enhancers -  0.04
     2 promoter/enhancer(s) are predicted
 Promoter Pos:   1522 LDF-  0.13 TATA box at   1488    18.93
 Enhancer Pos:   1597 LDF-  0.12
 Transcription factor binding sites/RegSite DB:
for promoter at position -    1522
  1468 (-) RSP00004     tagaCACGTaga
  1459 (+) RSP00010     cACGTG
  1456 (+) RSP00011     ctccACGTGgt
  1461 (+) RSP00016     caTGCAC
  1468 (-) RSP00016     caTGCAC
  1256 (-) RSP00026     gcttttgaTGACtTcaaacac
  1460 (+) RSP00065     ACGTGgcgc
  1460 (+) RSP00066     ACGTGccgc
  1459 (+) RSP00069     tACGTG
  1341 (+) RSP00071     GACGTC
  1346 (-) RSP00071     GACGTC
  

-------------------------------------------------
This mail sent through AceDSL WebMail (http://webmail.acedsl.com)
---


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Second Virtual Conference on Genomics and Bioinformatics

Sharing Knowledge with the World (No registration fees)
September 24-26, 2002
http://www.ndsu.nodak.edu/virtual-genomics/upcom2.htm
Deadline: August 15, 2002 for complete documents

Speakers List
http://www.ndsu.nodak.edu/virtual-genomics/program.htm

Review Committee List
http://www.ndsu.nodak.edu/virtual-genomics/reviewpanel.htm

Remote Locations:

North Dakota State Universty, ND, (USA) Host Access Grid
Academia Sinica, Taipei (TAIWAN) Real Player Version
ACCESS DC, Arlington, VA (USA) Access Grid Version
Boston University, MA (USA) Access Grid Version
CINECA AG Conference Facility, Bologna. (ITALY) Access Grid Version
Marshall University, WV (USA) Real Player Version
Montclair State University, NJ (USA) Real Player Version
Ohio Supercomputer Center, (OH) (USA) Access Grid Version
Oklahoma State Universityn, OK (USA) Real Player Version
Purdue University, West Lafayette, (IN) (USA) Access Grid Version
The University of Manchester, Manchester (UK) Access Grid Version
University of Hawaii, HI (USA) Access Grid Version
University of Kansas, KS (USA) Access Grid Version
University of Kentucky, KY (USA) Access Grid Version
University of Maine, (ME) (USA) Access Grid Version
University of Nebraska-Lincoln, (NE) (USA) Access Grid Version
University of New Mexico HPCERC, (NM) (USA) Access Grid Version
University of North Dakota, ND (USA) Real Player Version
University of Puerto Rico, San Juan. Puerto Rico Access Grid Version
Vrije Universiteit, Amsterdam, Amsterdam. The Netherlands Access Grid
Version

The "Virtual Conference on Genomics and Bioinformatics" is an advanced
environment for the exchange and discussion of information related to
innovations of the post-genomic era. Since genomic research has led to an
explosive rate of data accumulation and to a shift in the way biological
research is conducted, the conference features high profile researchers and
educators working actively in the development of new applications in the
areas of genomics and bioinformatics. While genomic technologies offer an
enormous scientific potential to understand genome functions, structure and
interaction, the increasing amount of data generated present new challenges
for biologists, sociologists, mathematicians, computer scientists and
biological modelers. Therefore the main goals of the Virtual Conference in
Genomics and Bioinformatics are:

1) Transcend geographical and economical barriers to the exchange of ideas
that facilitates the interaction and collaboration among scientists and
educators around the world.

2) Address the benefits and limitations of the newest developments in
post-genomic technologies.

3) Explore the social and ethical implications of genomic and bioinformatic
research

4) Establish new ways to introduce high school community about today's
multidisciplinary science.


Topics of the Virtual Conference includes but not limited to:

. Structural and Functional Genomics

. Post-Genomic Data Standardization, Management, and Integration

. Statistical and Computational Approaches for Gene Expression Analysis

. Sequence Annotation

. Metabolic Profiling and Simulation of Cellular Processes

. Social and Ethical Implications of Genomic Research

. High Throughput Computing and Distributed Memory Infrastructures

Willy Valdivia Granda
Plant Stress Genomics and Bioinformatics Group
North Dakota State University
PO BOX 5130
Fargo, USA
701 231-8440 (Lab)
701 231 8255 (Fax)
www.ndsu.edu/virtual-genomics

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