From BIOSCI-REQUEST Sat Sep 13 02:00:06 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id CAA11396; Sat, 13 Sep 1997 02:00:06 -0700 Received: (from biohelp@localhost) by net.bio.net (8.6.12/8.6.6) id CAA11378; Sat, 13 Sep 1997 02:00:04 -0700 Date: Sat, 13 Sep 1997 02:00:04 -0700 From: BIOSCI Administrator Message-Id: <199709130900.CAA11378@net.bio.net> To: bioherv@net.bio.net Subject: BIOSCI/bionet miniFAQ & Fundraiser (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From BIOSCI-REQUEST Sun Sep 14 11:15:24 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id LAA24441; Sun, 14 Sep 1997 11:15:24 -0700 Received: from anna-atm.rz.uni-frankfurt.de (root@anna-atm.rz.uni-frankfurt.de [141.2.150.5]) by net.bio.net (8.6.12/8.6.6) with SMTP id LAA24438; Sun, 14 Sep 1997 11:15:23 -0700 Message-Id: <199709141815.LAA24438@net.bio.net> Received: from dialin115.rz.uni-frankfurt.de by anna-atm.rz.uni-frankfurt.de with Local SMTP (PP); Sun, 14 Sep 1997 20:15:31 +0000 X-Sender: peijl@popmail.server.uni-frankfurt.de X-Mailer: Windows Eudora Version 1.4.4 Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Date: Sun, 14 Sep 1997 20:03:52 +0200 To: bioherv@net.bio.net From: Loewer@em.uni-frankfurt.de (Johannes Loewer) Subject: HERV Cell paper Dear Dixie and other HERVers, My comments to the paper by Conrad et al. in Cell (90, 303, 1997) are: 1. The FACS data presented in fig. 5 seems to demonstrate that cells trans- fected with a vector presumably expressing env of the HTDV/HERV-K provi- rus IDDMK(1,2)22 induce an expansion of V beta 7 specific T cells. This looks like a superantigen effect. I look forward to an independent confirma- tion. 2. It would be interesting to know whether an IDDMK(1,2)22 coded protein is expressed on the surface of transfected THP1 cells as the prototypic su- perantigen of MMTV is described as a transmembrane protein. 3. The published sequence of IDDMK(1,2)22 is very close to the sequence of the provirus HERV-K10. Therefore, the question arises whether other provi- ruses of the HTDV/HERV-K family also code for a superantigen. 4. Unfortunately, the sequences which are deposited in Genbank (accession numbers AFO12327-AFO12337) are not accesssible until today (Sept. 14). They should be released. 5. It is claimed that on the basis of potential splice donor and splice acceptor sites IDDMK(1,2)22 is expected to produce two subgenomic mRNAs. Indeed, we have described (in Northern blots and by sequencing, J.Virol. 69, 141, 1995) the production of subgenomic mRNAs by proviruses of the HTDV/HERV-K family including the two types of mRNAs postulated for IDDMK(1,2)22. I would like to know how (or with which program) the splice donor and splice acceptor sites were predicted, especially the most down- stream acceptor site. 6. I am pleased to notice that our method to detect unknown expressed retrovi- ral sequences (R-U5-PCR, Virol. 192, 501, 1993) has been successfully used (and to some extent further developed) by Schuepbach's group not only for the description of IDDMK(1,2)22 but also for the detection of en- dogenous avian retroviruses (EAV) in the supernatant of chicken cells (J.Virol. 71, 3005, 1997). 7. A general discussion is needed for the definition of what could be claimed to be a "novel mouse mammary tumor virus-related human endogenous retrovi- rus". Is a unique pattern of restriction enzyme cleavage sites and a diver- gence from published sequences by 5%-10% sufficient to justify such a claim? For me, IDDMK(1,2)22 is nothing else than another proviral sequence out of the fifty or so of the HTDV/HERV-K family known to be present in the human genome. Interestingly, the unique EAV sequence detected in the su- pernatant of chicken cells was not claimed to be a novel virus by Schuep- bach et al. 8. During the Mannheim Symposium we have proposed and there was agree- ment to give the name "HTDV/HERV-K" to the HERV-K family the prototype of which is Ono's HERV-K10 sequence and which is expressed as HTDV particles in human teratocarcinoma cells. So, this family can be discrimi- nated by name from other HERV-K families whose sequences (e.g. HERV- K/C4) show only 70% homology to the HERV-K10 sequence These comments are in addition to those sent by Jonas. I look forward to other contributions to this discussion. Johannes Loewer ______________________________________________ Johannes Loewer Tel.: +496103-772000 (office), +496103-67792 (home) Fax: +496103-771252 (office), +496103-699737 (home) Email: loewer@em.uni-frankfurt.de From BIOSCI-REQUEST Thu Sep 25 09:04:44 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id JAA24458; Thu, 25 Sep 1997 09:04:44 -0700 Received: from mail.unixg.ubc.ca (mail.unixg.ubc.ca [137.82.27.14]) by net.bio.net (8.6.12/8.6.6) with SMTP id JAA24455; Thu, 25 Sep 1997 09:04:43 -0700 Received: from [137.82.129.68] [137.82.129.68] by mail.unixg.ubc.ca with smtp (Exim 1.71 #1) id 0xEGPH-0002Cw-00; Thu, 25 Sep 1997 09:04:49 -0700 X-Sender: dixie@pop.unixg.ubc.ca Message-Id: Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Date: Thu, 25 Sep 1997 09:05:23 -0800 To: bioherv@net.bio.net From: dixie@unixg.ubc.ca (Dixie Mager) Subject: HERV-K IDDM Thanks to Clive P., Mark B., Jonas and Johannes for their comments on the Cell paper. I agree that its an impressive piece of work and should help the HERV field. Many of you may have seen the follow-up News and Views in the August 28 issue of Nature by Benoist and Mathis. I was surprised to read their statement "The retrovirus had never previously been identified but it shares homology with mouse mammary tumor viruses". HERV-K is not mentioned in their article! Perhaps someone from the HERV-K field should write a letter to Nature to set the record straight. Any opinions? Dixie Dixie Mager, Ph.D. Terry Fox Laboratory B.C. Cancer Agency 601 W. 10th Avenue Vancouver, B.C. V5Z1L3 Canada phone: 604-877-6070 ext. 3185 fax: 604-877-0712 From BIOSCI-REQUEST Thu Sep 25 14:10:59 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id OAA05639; Thu, 25 Sep 1997 14:10:59 -0700 Received: from mailhub.auhs.edu (mailhub.auhs.edu [204.170.0.99]) by net.bio.net (8.6.12/8.6.6) with ESMTP id OAA05636; Thu, 25 Sep 1997 14:10:58 -0700 Received: from oscar.auhs.edu by mailhub.auhs.edu (PMDF V5.1-10 #16327) with ESMTP id <01IO2FJ2ETCO000XP8@mailhub.auhs.edu> for bioherv@net.bio.net; Thu, 25 Sep 1997 17:09:10 EST Received: from oscar.auhs.edu by oscar.auhs.edu (PMDF V5.1-5 #16328) id <01IO2FK9GYZK000A07@oscar.auhs.edu> for bioherv@net.bio.net; Thu, 25 Sep 1997 17:10:07 -0500 (EST) Date: Thu, 25 Sep 1997 17:10:07 -0500 (EST) From: boyd@auhs.edu Subject: Re: HERV-K IDDM In-reply-to: Sender: BOYD@auhs.edu To: Dixie Mager Cc: bioherv@net.bio.net Message-id: MIME-version: 1.0 Content-type: TEXT/PLAIN; charset=US-ASCII I agree... particularly since there are people currently trying to get a bandwagon going regarding "MMTV-LIKE" HERVs/Human retroviruses(????) and their involvement in other human disorders such as breast cancer. The potential exists for this very interesting story to be misused for sales pitches. Maybe we should indeed draft a clarifiying note. Best wishes Boyd ______________________________________________________________________________ Mark Boyd Department of Medicine, Mail stop 412, Allegheny University, Broad & Vine, Philadelphia PA 19102-1192 Tel 215 762 8659 Fax 215 762 8857 BOYD@auhs.edu (from June 16th this will become boyd@auhs.edu) ______________________________________________________________________________ "I can picture in my mind a world without war, a world without hate. And I can picture us attacking that world, because they'd never expect it." From BIOSCI-REQUEST Fri Sep 26 08:42:56 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id IAA01245; Fri, 26 Sep 1997 08:42:56 -0700 Received: from sparrow (ip18.140.isdn.hogia.net [195.78.140.18]) by net.bio.net (8.6.12/8.6.6) with SMTP id IAA01240; Fri, 26 Sep 1997 08:42:54 -0700 From: jonas.blomberg@alinks.se Message-Id: <199709261542.IAA01240@net.bio.net> Date: Fri, 26 Sep 1997 17:44:01 +0100 To: dixie@unixg.ubc.ca, bioherv@net.bio.net Subject: Re: HERV-K IDDM MIME-version: 1.0 Content-Type: text/plain; charset=ISO-8859-1 Content-transfer-encoding: quoted-printable X-Mailer: TFS Gateway /220000000/220020196/220000685/220110092/ Dixie, I agree, we should make ourselves heard=2E We risk getting overrun=20 by new converts to HERVism=2E Did I miss Clive's comment? Could someone resend it to me? Jonas *************< Jonas=2EBlomberg@alinks=2Ese >************ Jonas Blomberg, M=2ED=2E, Ph=2ED=2E professor, Section of Virology, Department of Clinical Microbiology=20 University of Uppsala Academic Hospital S-751 85 Uppsala, Sweden (Street address: Dag Hammarskjolds v=2E 17) Voice: +46-18-665593 (office) +46-40-412653 (home)=20 Fax: +46-18-559157 (office) +46-40-411165 (home) Pager: +46-746498980 =20 ***************************************************** =2E=2E=2EA DOCMAIL MESSAGE! From BIOSCI-REQUEST Fri Sep 26 16:01:21 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id QAA26925; Fri, 26 Sep 1997 16:01:21 -0700 Received: from grover.auhs.edu (grover.auhs.edu [204.170.0.98]) by net.bio.net (8.6.12/8.6.6) with ESMTP id QAA26922; Fri, 26 Sep 1997 16:01:19 -0700 Received: from oscar.auhs.edu by grover.auhs.edu (PMDF V5.1-10 #16327) with ESMTP id <01IO3XQ1U2NC0000TT@grover.auhs.edu> for bioherv@net.bio.net; Fri, 26 Sep 1997 19:00:59 EST Received: from oscar.auhs.edu by oscar.auhs.edu (PMDF V5.1-5 #16328) id <01IO3XPQR010000DR3@oscar.auhs.edu> for bioherv@net.bio.net; Fri, 26 Sep 1997 19:00:44 -0500 (EST) Date: Fri, 26 Sep 1997 19:00:43 -0500 (EST) From: boyd@auhs.edu Subject: Re: Re[2]: HERV-K IDDM In-reply-to: <01IO3IEHCD1G000Z0Y@mailhub.auhs.edu> Sender: BOYD@auhs.edu To: jonas.blomberg@alinks.se Cc: bioherv@net.bio.net Reply-to: boyd@auhs.edu Message-id: MIME-version: 1.0 Content-type: TEXT/PLAIN; charset=US-ASCII On Fri, 26 Sep 1997 jonas.blomberg@alinks.se wrote: > Mark, > > Is this an attack on me and Patrik?? Not at all, My comment was directed at the questionable "novelty" and the possibility that other unscrupulous persons might try to connect "novel MMTV-like" with e.g. a novel human retrovirus that has been claimed to be involved in human mammary cancer. >MMTV-like is not a misnomer. see above > The most well-studied exogenous member of the group is an > acceptable point of reference, as we have discussed for many > years. What attempts to misuse the interesting story are there? > > I think this new twist on the superantigen story shows that the > MMTV parabola is relevant. > > Jonas > > ______________________________ Reply Separator _________________________________ > Subject: Re: HERV-K IDDM > Author: MIME:boyd@auhs.edu at INTERNET > Date: 1997-09-25 23.23 > > > > I agree... particularly since there are people currently trying to get a > bandwagon going regarding "MMTV-LIKE" HERVs/Human retroviruses(????) and > their involvement in other human disorders such as breast cancer. The > potential exists for this very interesting story to be misused for > sales pitches. Maybe we should indeed draft a clarifiying note. > > Best wishes > > Boyd > > ______________________________________________________________________________ > > > Mark Boyd > Department of Medicine, Mail stop 412, > Allegheny University, > Broad & Vine, > Philadelphia PA 19102-1192 > > Tel 215 762 8659 > Fax 215 762 8857 > > BOYD@auhs.edu (from June 16th this will become boyd@auhs.edu) > ______________________________________________________________________________ > > "I can picture in my mind a world without war, a world without hate. > And I can picture us attacking that world, because they'd never expect it." > > > > *************< Jonas.Blomberg@alinks.se >************ > Jonas Blomberg, M.D., Ph.D. > professor, Section of Virology, > Department of Clinical Microbiology > University of Uppsala > Academic Hospital > S-751 85 Uppsala, Sweden > > (Street address: Dag Hammarskjolds v. 17) > > Voice: +46-18-665593 (office) +46-40-412653 (home) > Fax: +46-18-559157 (office) +46-40-411165 (home) > Pager: +46-746498980 > ***************************************************** > ...A DOCMAIL MESSAGE! > ______________________________________________________________________________ Mark Boyd Department of Medicine, Mail stop 412, Allegheny University, Broad & Vine, Philadelphia PA 19102-1192 Tel 215 762 8659 Fax 215 762 8857 BOYD@auhs.edu (from June 16th this will become boyd@auhs.edu) ______________________________________________________________________________ "I can picture in my mind a world without war, a world without hate. And I can picture us attacking that world, because they'd never expect it." From BIOSCI-REQUEST Sat Sep 27 04:04:49 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id EAA23375; Sat, 27 Sep 1997 04:04:49 -0700 Received: from sparrow (ip18.140.isdn.hogia.net [195.78.140.18]) by net.bio.net (8.6.12/8.6.6) with SMTP id EAA23372; Sat, 27 Sep 1997 04:04:46 -0700 From: jonas.blomberg@alinks.se Message-Id: <199709271104.EAA23372@net.bio.net> Date: Sat, 27 Sep 1997 13:06:26 +0100 To: boyd@auhs.edu Cc: bioherv@net.bio.net Subject: Re[4]: HERV-K IDDM MIME-version: 1.0 Content-Type: text/plain; charset=ISO-8859-1 Content-transfer-encoding: quoted-printable X-Mailer: TFS Gateway /220000000/220020196/220000685/220110092/ Mark, >> Is this an attack on me and Patrik??=20 > >Not at all,=20 >My comment was directed at the questionable "novelty" and the=20 >possibility that other unscrupulous persons might try to connect=20 >"novel MMTV-like" with e=2Eg=2E a novel human retrovirus that has=20 >been claimed to be involved in human mammary cancer=2E I agree=2E Jonas ______________________________ Reply Separator ____________________________= _____ Subject: Re: Re[2]: HERV-K IDDM Author: MIME:boyd@auhs=2Eedu at INTERNET Date: 1997-09-27 1=2E20 On Fri, 26 Sep 1997 jonas=2Eblomberg@alinks=2Ese wrote: > Mark, >=20 > Is this an attack on me and Patrik??=20 Not at all,=20 My comment was directed at the questionable "novelty" and the possibility=20 that other unscrupulous persons might try to connect "novel MMTV-like"=20 with e=2Eg=2E a novel human retrovirus that has been claimed to be involved= in=20 human mammary cancer=2E >MMTV-like is not a misnomer=2E=20 see above > The most well-studied exogenous member of the group is an=20 > acceptable point of reference, as we have discussed for many=20 > years=2E What attempts to misuse the interesting story are there?=20 >=20 > I think this new twist on the superantigen story shows that the=20 > MMTV parabola is relevant=2E >=20 > Jonas >=20 > ______________________________ Reply Separator=20 _________________________________ > Subject: Re: HERV-K IDDM > Author: MIME:boyd@auhs=2Eedu at INTERNET=20 > Date: 1997-09-25 23=2E23 >=20 >=20 >=20 > I agree=2E=2E=2E particularly since there are people currently trying to=20= get a=20 > bandwagon going regarding "MMTV-LIKE" HERVs/Human retroviruses(????) and=20 > their involvement in other human disorders such as breast cancer=2E The=20 > potential exists for this very interesting story to be misused for=20 > sales pitches=2E Maybe we should indeed draft a clarifiying note=2E >=20 > Best wishes >=20 > Boyd >=20 > ___________________________________________________________________________= ___=20 >=20 >=20 > Mark Boyd > Department of Medicine, Mail stop 412,=20 > Allegheny University, > Broad & Vine, > Philadelphia PA 19102-1192 >=20 > Tel 215 762 8659 > Fax 215 762 8857 >=20 > BOYD@auhs=2Eedu (from June 16th this will become boyd@auhs=2Eedu) =20 > ___________________________________________________________________________= ___=20 >=20 > "I can picture in my mind a world without war, a world without hate=2E > And I can picture us attacking that world, because they'd never expect it=2E= "=20 >=20 >=20 >=20 > *************< Jonas=2EBlomberg@alinks=2Ese >************=20 > Jonas Blomberg, M=2ED=2E, Ph=2ED=2E > professor, Section of Virology, > Department of Clinical Microbiology=20 > University of Uppsala > Academic Hospital > S-751 85 Uppsala, Sweden >=20 > (Street address: Dag Hammarskjolds v=2E 17)=20 >=20 > Voice: +46-18-665593 (office) +46-40-412653 (home)=20 > Fax: +46-18-559157 (office) +46-40-411165 (home)=20 > Pager: +46-746498980 =20 > ***************************************************** > =2E=2E=2EA DOCMAIL MESSAGE!=20 >=20 ___________________________________________________________________________= ___ Mark Boyd Department of Medicine, Mail stop 412,=20 Allegheny University, Broad & Vine, Philadelphia PA 19102-1192 Tel 215 762 8659 Fax 215 762 8857 BOYD@auhs=2Eedu (from June 16th this will become boyd@auhs=2Eedu) =20 ___________________________________________________________________________= ___ "I can picture in my mind a world without war, a world without hate=2E And I can picture us attacking that world, because they'd never expect it=2E= " *************< Jonas=2EBlomberg@alinks=2Ese >************ Jonas Blomberg, M=2ED=2E, Ph=2ED=2E professor, Section of Virology, Department of Clinical Microbiology=20 University of Uppsala Academic Hospital S-751 85 Uppsala, Sweden (Street address: Dag Hammarskjolds v=2E 17) Voice: +46-18-665593 (office) +46-40-412653 (home)=20 Fax: +46-18-559157 (office) +46-40-411165 (home) Pager: +46-746498980 =20 ***************************************************** =2E=2E=2EA DOCMAIL MESSAGE! From BIOSCI-REQUEST Mon Sep 29 08:32:40 1997 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12/8.6.6) id IAA03541; Mon, 29 Sep 1997 08:32:40 -0700 Received: from grip1.ochsner.org (ochsner.ochsner.org [147.206.5.1]) by net.bio.net (8.6.12/8.6.6) with SMTP id IAA03538; Mon, 29 Sep 1997 08:32:38 -0700 Received: from mss.ochsner.org by grip1.ochsner.org (AIX 4.1/UCB 5.64/4.03) id AA22314; Mon, 29 Sep 1997 10:09:44 -0500 Received: from MC4HUB-Message_Server by ochsner.org with Novell_GroupWise; Mon, 29 Sep 1997 10:28:53 -0500 Message-Id: X-Mailer: Novell GroupWise 4.1 Date: Mon, 29 Sep 1997 10:35:36 -0500 From: ANDY MASON To: bioherv@net.bio.net Subject: receiving HERV news Mime-Version: 1.0 Content-Type: text/plain Content-Disposition: inline I would like to recieve further information about HERVs through the bioherv service. How do I join up? Andy Mason