From owner-bio-matrix@net.bio.net Sun Apr 03 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!wupost!ukma!seqanal.mi.uky.edu!mpm
From: mpm@seqanal.mi.uky.edu (Mark Mattson)
Newsgroups: bionet.molbio.bio-matrix
Subject: BinHex locale?
Date: 4 Apr 1994 14:13:06 GMT
Organization: University of Kentucky, Dept. of Math Sciences
Lines: 6
Message-ID: <2np79i$8aa@s.ms.uky.edu>
NNTP-Posting-Host: seqanal.mi.uky.edu
X-Newsreader: TIN [version 1.1 PL9]

Can anyone point me to a public domain copy of BinHex 4.0?

Thanks, 
Steven W. Barger, Ph.D.
Sanders-Brown Center on Aging


From owner-bio-matrix@net.bio.net Mon Apr 04 23:00:00 1994
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.molbio.bio-matrix
Subject: COMPMED 94 FINAL SCHEDULE
Date: 5 Apr 1994 12:39:10 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 50
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9404051939.AA08469@morpheus>
NNTP-Posting-Host: net.bio.net

		   FINAL PROGRAM ANNOUNCEMENT

FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE AND PUBLIC HEALTH
			24-28 April 1994
		Hyatt on the Lake, Austin, Texas

The final program for the First World Congress On Computational
Medicine and Public Health has now been set. Over 200 speakers
will be presenting work in a variety of applications areas
related to medicine and public health. Registration is still
open for attendees. Registration details and/or a copy of the
schedule at a glance, schedule-in-detail may be requested by
sending an email request to

	compmed94@chpc.utexas.edu

or by calling
	
	512-471-2472

or by faxing
	
	512-471-2445

There is no ftp form of the conference schedule due to the
size of the file. We will be happy to fax/send a copy to anyone
who requests it. The conference proceedings will appear as
a series of volumes published by World Scientific. If you are
interested in possibly submitting a paper for the proceedings,
please contact

	mwitten@chpc.utexas.edu

or call

	512-471-2457

The overwhelming response to this congress has already
justified having a second world congress in the future. The tentative
schedule is to have in in 3 years. If you are interested in
participating at the 2nd World Congress On Computational Medicine
and Public Health, please contact 

     Dr. Matthew Witten 
	Congress Chair
   mwitten@chpc.utexas.edu





From owner-bio-matrix@net.bio.net Mon Apr 04 23:00:00 1994
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.molbio.bio-matrix
Subject: COMPMED 94 FINAL SCHEDULE
Date: 5 Apr 1994 12:38:53 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 50
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <9404051939.AA08440@morpheus>
NNTP-Posting-Host: net.bio.net

		   FINAL PROGRAM ANNOUNCEMENT

FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE AND PUBLIC HEALTH
			24-28 April 1994
		Hyatt on the Lake, Austin, Texas

The final program for the First World Congress On Computational
Medicine and Public Health has now been set. Over 200 speakers
will be presenting work in a variety of applications areas
related to medicine and public health. Registration is still
open for attendees. Registration details and/or a copy of the
schedule at a glance, schedule-in-detail may be requested by
sending an email request to

	compmed94@chpc.utexas.edu

or by calling
	
	512-471-2472

or by faxing
	
	512-471-2445

There is no ftp form of the conference schedule due to the
size of the file. We will be happy to fax/send a copy to anyone
who requests it. The conference proceedings will appear as
a series of volumes published by World Scientific. If you are
interested in possibly submitting a paper for the proceedings,
please contact

	mwitten@chpc.utexas.edu

or call

	512-471-2457

The overwhelming response to this congress has already
justified having a second world congress in the future. The tentative
schedule is to have in in 3 years. If you are interested in
participating at the 2nd World Congress On Computational Medicine
and Public Health, please contact 

     Dr. Matthew Witten 
	Congress Chair
   mwitten@chpc.utexas.edu





From owner-bio-matrix@net.bio.net Mon Apr 04 23:00:00 1994
Path: biosci!rutgers!cis.ohio-state.edu!news.sei.cmu.edu!bb3.andrew.cmu.edu!cantaloupe.srv.cs.cmu.edu!fs7.ece.cmu.edu!europa.eng.gtefsd.com!darwin.sura.net!lhc!lhc!hunter
From: hunter@work.nlm.nih.gov (Larry Hunter)
Newsgroups: bionet.molbio.bio-matrix
Subject: HICSS-28 Biotechnology Computing Track call for papers
Message-ID: <HUNTER.94Mar31130642@work.nlm.nih.gov>
Date: 31 Mar 94 18:06:42 GMT
Sender: news@nlm.nih.gov
Reply-To: Hunter@nlm.nih.gov
Organization: National Library of Medicine
Lines: 152


				   
			   Call for Papers
				   
		    Biotechnology Computing Track
	Hawaii International Conference on System Sciences 28
			   
		     Maui, Hawaii --- January 3-6, 1995

The twenty-eighth annual Hawaii International Conference on System Sciences
(HICSS) will include a three day conference track on Biotechnology
Computing.  The Biotechnology Computing Track provides a forum for the
interchange of ideas, research results, and system building activities in
all areas of computation related to biology.  It includes presentations of
original research, tutorials, advanced seminars and a distinguished guest
lecture.  The conference is sponsored by the University of Hawaii in
cooperation with the Association for Computing Machinery (ACM), the IEEE
Computer Society, and the Pacific Research Institute for Information Systems
and Management (PRIISM).

Advances in biotechnology generally and in the international Human Genome
Project are creating an explosion of fundamental biological data underlying
all life processes.  The computational problems in gathering, managing and
analyzing this explosion are daunting, but the challenges are exciting and
the potential payoff is very high.  Every aspect of computer science is
involved, from algorithm development, systems integration and advanced
database management to image analysis, parallel computing, artificial
intelligence and robotics.  The Biotechnology Computing Track presents the
leading edge of this research in five minitracks, each focused on a rapidly
evolving research area.

Relevant papers are solicited for each of the minitrack areas listed below.
Papers must be previously unpublished, and should be from 22-26 double
spaced pages in length, including figures.  Submitted papers are subject to
a rigorous peer review process with written reviews from at least five
referees.  Accepted papers will be published in the conference proceedings
which is also made generally available by the IEEE Computer Society Press.
Prospective authors are urged to contact the appropriate minitrack chair as
early as possible.  Please leave adequate time for international mail, as
all deadlines are firm.

For general information, or proposals for tutorials, advanced seminars and
review papers, contact the track chair:

Lawrence Hunter  (hunter@nlm.nih.gov)
National Library of Medicine
Building 38A, Mail Stop 54
Bethesda, MD 20894 USA
+1 (301) 496-9300
+1 (301) 496-0673 (fax)

The other members of the Track steering committee are:

* Tom Marr, Cold Spring Harbor Laboratory, USA
* John Wootton, National Center for Biotechnology Information, USA
* Minoru Kanehisa, Kyoto University, Japan
* Peter Edwards, Aberdeen University, Scotland

DEADLINES:
 
Full manuscripts must be RECEIVED by June 15, 1994
Notification of accepted papers will be sent by August 31, 1994
Accepted camera ready copy must be RECEIVED by October 1, 1994

International mail can be slow.  We recommend use of courier services
to international destinations.

BIOTECHNOLOGY COMPUTING MINITRACKS AND CHAIRS.  

Please contact the relevant minitrack chair as soon as possible for further
information on the requirements and deadlines for that minitrack.

* Project-Oriented Databases and Knowledge Bases in Genome Research:
  Database and knowledge base tools and technologies that support the
  management of specific research groups or purposes, e.g.  community
  databases for specialized research groups, laboratory notebooks, data
  management system supporting experiments, links between different
  databases, biological function knowledge bases, knowledge representation
  for biological functions and data models and structures for genome data.

  Toshihisa Takagi (takagi@ims.u-tokyo.ac.jp)

  Human Genome Center, The Institute of Medical Science, 
  The University of Tokyo 
  4-6-1 Shirokanedai, Minato-ku, Tokyo 108 JAPAN 
  Tel. +81-3-3443-8111 ex.613 
  Fax: +81-3-3440-6173

* Parallel Computing for Computational Biology: The use of parallel and
  distributed computer systems and software in computational biology,
  including for molecular modeling, protein folding, sequence analysis,
  linkage analysis and other problems in the biological sciences.

  Timothy G. Mattson (tgm@ssd.intel.com)  
  L. Ridgway Scott (scott@uh.edu)
  
  Intel Corp., Supercomputer Systems Division
  Mail Stop CO6-09                     	
  14924 N.W. Greenbrier Pkwy
  Beaverton, Oregon 97229 USA
  phone: +1 (503) 531-5627
  fax: +1 (503) 531-5501

* Stochastic Models and Grammars for Bioinformatics: including hidden Markov
  models, regular grammar, context-free grammar, stochastic grammars and
  other stochastic approaches to recognize or analyze genetic/protein
  sequences and their structures.

  Kiyoshi Asai (asai@etl.go.jp)
  Hidetoshi Tanaka (htanaka@icot.or.jp)

  Institute for New Generation Computer Technology
  Mita Kokusai Bldg. 21F, 1-4-28, Mita, Minato-ku, Tokyo 108
  Japan
  FAX    : +81-3-3456-1618

* Computer Tools for Molecular Modeling: current research in computer
  algorithms and systems for molecular modeling and drug design.

  Teri E. Klein (klein@cgl.ucsf.edu)
  Mark C. Surles (surles@sdsc.edu)

  University of California, San Francisco
  513 Parnassus Avenue, Box 0446
  San Francisco, California 94143 USA
  phone: +1 (415) 476-0663
  fax: +1 (415) 502-1755

* Protein Structure Prediction: Novel computational advances relevant to
  protein structure prediction from the primary sequence, including direct
  and "inverse" folding, homology-derived, statistical, machine learning,
  analytic, modeling, pattern-based, and related methods.

  Richard Lathrop (rickl@ai.mit.edu)
  Keith Dunker (dunker@bobcat.csc.wsu.edu)

  MIT AI Laboratory
  NE43-795
  545 Technology Square
  Cambridge, MA 02139 USA
  +1 (617) 253-8833
  +1 (617) 258-8682 (fax)

--
Lawrence Hunter, PhD.
National Library of Medicine
Bldg. 38A, MS-54
Bethesda. MD 20894 USA
tel: +1 (301) 496-9300
fax: +1 (301) 496-0673 
internet: hunter@nlm.nih.gov
encryption: public key via RIPEM server or "finger hunter@work.nlm.nih.gov"

From owner-bio-matrix@net.bio.net Tue Apr 05 23:00:00 1994
Path: biosci!bcm!cs.utexas.edu!usc!nic-nac.CSU.net!ctp.org!not-for-mail
From: jng@eis.calstate.edu (Joseph S. Ng)
Newsgroups: bionet.molbio.bio-matrix
Subject: Staphylotoxins
Date: 6 Apr 1994 12:35:15 -0700
Organization: California Technology Project of The Calif State Univ
Lines: 12
Message-ID: <2nv2tj$26f@eis.calstate.edu>
NNTP-Posting-Host: eis.calstate.edu


Anyone out there with some information regarding the antigenic mature of 
toxins produced by Staphylococcus auresus and its related microbial 
complexes is kindly invited to share your insights...
--
---
JoE
Ng, that is...

Squire in absentia
DAWOOD'S KNIGHTS OF THE NOT SO ROUND COFFEE SHOP TABLE


From owner-bio-matrix@net.bio.net Wed Apr 06 23:00:00 1994
Path: biosci!biosci!not-for-mail
From: noordewi@binnacle.rutgers.edu (Michiel)
Newsgroups: bionet.announce,bionet.general,bionet.molbio.bio-matrix
Subject: Machine Learning 94 Workshop on Computational Molecular Biology
Date: 6 Apr 1994 20:55:31 -0700
Organization: Rutgers Univ., New Brunswick, N.J.
Lines: 64
Sender: kristoff@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: bionet
Message-ID: <Apr.6.17.46.20.1994.18922@binnacle.rutgers.edu>
NNTP-Posting-Host: net.bio.net
Cc: noordewi@cs.rutgers.edu
Xref: biosci bionet.announce:1061 bionet.general:8537 bionet.molbio.bio-matrix:478



		 Computational Molecular Biology and
		      Machine Learning Workshop
				   
		   Machine Learning Conference 1994

			  Program Committee:
				   
	       Michiel Noordewier (Rutgers University)
	       Lindley Darden (Rockefeller University)
				   
Description and Focus
---------------------

This workshop will focus on the application of methods from machine
learning to the promising problem area of molecular biology.  A goal
is to consolidate a machine learning faction in the emerging field of
computational biology.

One problem area is identified as genetic sequence search and
analysis, and protein structure prediction.  Biological sequences have
become a ready source of sample data for machine learning approaches
to classification.  Recently such sequences have also provided
problems for sophisticated pattern recognition paradigms, including
those borrowed from computational linguistics, Bayesian methods, and
artificial neural networks.  This workshop will bring together workers
using such diverse approaches, and will focus on the rich set of
problems presented by the recent availability of extensive biological
sequence information.

Another area of applicability of ML techniques to molecular biology is
in the application of computational discovery methods.  Such methods
are employed for forming, ranking, evaluating, and improving
hypotheses.  Learning strategies using analogies or homologies among
molecules or processes from different organisms or species are also of
interest.

The format of the workshop will be the presentation of short papers
followed by panel discussions.

Submission Requirements
-----------------------

Persons wishing to attend the workshop should submit three copies of a
1-2 page research summary including a list of relevant publications,
along with a phone number and an electronic mail address.  

Persons wishing to make presentations at the workshop should submit
three copies of a short paper (no more than 10 pages) or extended
abstract, in addition to the research summary.  All submissions must
be received by May 1, 1994.  Notification of acceptance or
rejection will be mailed to applicants by May 15, 1994.

A set of working notes will be distributed at the workshop.  Camera
ready copies of papers accepted for inclusion in the working notes of
the workshop will be due on June, 15, 1994.

The timetable is as follows:

        Abstracts, papers, etc due to chair             1 May
        Decisions made, submitters get feedback        15 May
        Final working-note submissions rcv'd by chair  15 June
        workshop date                                  10 July, 1994

From owner-bio-matrix@net.bio.net Wed Apr 06 23:00:00 1994
Path: biosci!UAFSYSB.UARK.EDU!MF06096
From: MF06096@UAFSYSB.UARK.EDU
Newsgroups: bionet.molbio.bio-matrix
Subject: signoff
Date: 6 Apr 1994 23:12:11 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 6
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199404070612.XAA00403@net.bio.net>
NNTP-Posting-Host: net.bio.net

unsubscribe bio-matrix
-Mark Franklin

************************************************************************
*        MARK FRANKLIN   UNIVERSITY OF ARKANSAS   (501) 575-2905       *
************************************************************************

From owner-bio-matrix@net.bio.net Thu Apr 07 23:00:00 1994
Path: biosci!internet!biosci!not-for-mail
From: kristoff (David Kristofferson)
Newsgroups: bionet.molbio.bio-matrix
Subject: IMPORTANT BIOSCI INFORMATION
Date: 8 Apr 1994 02:00:15 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 244
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199404080900.CAA16294@net.bio.net>
NNTP-Posting-Host: net.bio.net


Three important items follow: BIOSCI archive searching by e-mail, the
BIOSCI FAQ, and the BIOSCI User Address Directory form.  If you have
not yet listed yourself in our e-mail address directory, please take a
few minutes to complete and return the form below.  If your address
information has changed since you listed yourself, please send us an
updated form.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net



	  **** SEARCHING BIOSCI ARCHIVES WITH WAISMAIL ****

E-mail users can search the BIOSCI archives by using our waismail
e-mail server.  For instructions send the message

help

to waismail@net.bio.net.  Leave the Subject: line blank.  Other
methods of searching the archives via WAIS and gopher are described in
the BIOSCI FAQ.


       **** BIOSCI FREQUENTLY ASKED QUESTIONS (FAQ) SHEET ****

New users of BIOSCI/bionet may want to read the "Frequently Asked
Questions" or "FAQ" sheet for BIOSCI.  The FAQ provides details on how
to participate in these forums and is available for anonymous FTP from
net.bio.net [134.172.2.69] in pub/BIOSCI/doc/biosci.FAQ or for
retrieval by gopher to net.bio.net, port 70.  It may also be requested
by sending e-mail to biosci-help@net.bio.net (use plain English for
your request).  The FAQ is also posted on the first of each month to
the newsgroup BIONEWS/bionet.announce immediately following the
posting of the BIOSCI information sheet.


	       **** BIOSCI USER ADDRESS DIRECTORY ****

Please take this opportunity to add your name and address information
to the BIOSCI User Address Database if you have not already done so.

Below is the address form that we would like each reader of the
BIOSCI/bionet newsgroups to complete and return if you would like to
be listed in our database.  The database serves as a directory that
enables biologists, who are currently using (or even just reading) the
BIOSCI newsgroups, to look up e-mail addresses and other information
about our users.

The address database is reindexed nightly for WAIS and waismail access
(waismail is our WAIS e-mail server, more below) and will also be
available for access via other gopher sites if they wish to permit it.
The raw unindexed data is available for FTP from net.bio.net and is
atomized sufficiently to allow import into your local RDBMS should you
so desire.

Please carefully follow the instructions for completing the form
below and return it to either of the following two addresses
(whichever is more convenient for you).  Thanks in advance for taking
the time to complete and return the form.

Addresses for returning forms         Location        Network
-----------------------------         --------        -------
biovote@net.bio.net                   U.S.A.          Internet/BITNET
biovote@daresbury.ac.uk               U.K.            JANET


	     MAKING SURE THAT YOUR INFORMATION IS CURRENT

This notice will be mailed bimonthly to each newsgroup.  You should
check our WAIS source or waismail e-mail server from time-to-time to
see if your address information is still up-to-date.  Send the message

help

to waismail@net.bio.net for instructions on using waismail.  Leave the
Subject: line in your message blank.


		  Using Gopher to complete the form
                  ---------------------------------

If you don't want to use a text editor, you can also use Dan
Jacobson's gopher site to fill out the address database form as
follows.  Otherwise skip this section on gopher and proceed to the
instructions for filling out the form below.

> To add yourself to the database just point your
> gopher client at merlot.gdb.org and select the following:
> 
> -->  15. Searching For Biologists/
> 
>  -->  9.  E-mail Addresses of Biosci-Bionet Users/
> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

> Europeans can point their gopher client at gopher.csc.fi and add their
> information to the database. All entries will be mailed directly to
> Dave for incorporation in a wais source.
> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


	    IMPORTANT INSTRUCTIONS - PLEASE READ CAREFULLY

Please enter all responses after the : on each line, leaving one (1)
blank space after the : (i.e., before the start of your text).

Please do NOT extend your responses past the end of each line (80
characters) or alter any of the field identifiers such as "first name: ". 
Several lines are provided at the end of the form for comments, but,
please adhere to the line length restriction.

On the date: line, please enter the date in the DD-MM-YY format, e.g.,
05-05-93 for 5 May 1993.  This line will tell others when the
information was last updated.  Please be sure to include the 0's for
single digit days or months, e.g., 05-05-93, not 5-5-93.

Note that the "e-mail network: " line below is for specifying, e.g.,
"Internet," "BITNET," "EARN," "JANET," or whatever other network that
your computer may be on.

If you are uncertain about any field, please feel free to leave it
blank, but please DO NOT DELETE the field identifier from the form!

In the first field below, "New information or Update ...", please
enter "N" if this is the first time that you have registered in the
directory or "U" if you are correcting a listing that you sent to us
previously.

The comment: lines may be used for anything that you like but PLEASE
DO NOT DELETE THEM FROM THE FORM OR ALTER THEM.  One suggested use is
to list the names of the newsgroups in which you participate.  Please
use the MAILING LIST name (see below - the latest version of the list
can be requested from biosci@net.bio.net) instead of the USENET name
even if you don't participate by e-mail.  WAIS might get confused by
the periods in the USENET names.  This allows one to retrieve via WAIS
or waismail the list of participants in a particular group.

For example:

comment: ARABIDOPSIS PLANT-BIOLOGY BIONEWS

On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIO-SOFTWARE               bionet.software
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

Listing newsgroups on the comment: line is optional, of course.

Thanks again for your cooperation!



--------------- please cut here and return portion below ---------------

New information or Update to old record (enter N or U): 
date (DD-MM-YY): 
first name: 
middle initial: 
family name: 
job title: 
e-mail address: 
e-mail network: 
phone number: 
FAX number: 
institution: 
address1: 
address2: 
address3: 
city: 
state/province: 
country: 
postal code: 
research interest: 
research interest: 
comment: 
comment: 
comment: 
comment: 
comment: 

From owner-bio-matrix@net.bio.net Thu Apr 07 23:00:00 1994
Path: biosci!UMIACS.UMD.EDU!darden
From: darden@UMIACS.UMD.EDU (Lindley Darden)
Newsgroups: bionet.molbio.bio-matrix
Subject: ML94compbioworkshop
Date: 8 Apr 1994 11:09:41 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 96
Sender: daemon@net.bio.net
Distribution: bionet
Message-ID: <199404081810.OAA29365@skippy.umiacs.UMD.EDU>
NNTP-Posting-Host: net.bio.net


-----------------------------------------------------------------------------
                 Computational Molecular Biology and
                      Machine Learning Workshop

                   Machine Learning Conference 1994
		         Rutgers University

                          Program Committee:

               Michiel Noordewier (Rutgers University)
               Lindley Darden (Rockefeller University)

Description and Focus
---------------------

This workshop will focus on the application of methods from machine
learning to the promising problem area of molecular biology.  A goal
is to consolidate a machine learning faction in the emerging field of
computational biology.

One problem area is identified as genetic sequence search and
analysis, and protein structure prediction.  Biological sequences have
become a ready source of sample data for machine learning approaches
to classification.  Recently such sequences have also provided
problems for sophisticated pattern recognition paradigms, including
those borrowed from computational linguistics, Bayesian methods, and
artificial neural networks.  This workshop will bring together workers
using such diverse approaches, and will focus on the rich set of
problems presented by the recent availability of extensive biological
sequence information.

Another area of applicability of ML techniques to molecular biology is
in the application of computational discovery methods.  Such methods
are employed for forming, ranking, evaluating, and improving
hypotheses.  Learning strategies using analogies or homologies among
molecules or processes from different organisms or species are also of
interest.

The format of the workshop will be the presentation of short papers
followed by panel discussions.

Submission Requirements
-----------------------

Persons wishing to attend the workshop should submit three copies of a
1-2 page research summary including a list of relevant publications,
along with a phone number and an electronic mail address.

Persons wishing to make presentations at the workshop should submit
three copies of a short paper (no more than 10 pages) or extended
abstract, in addition to the research summary.  All submissions must
be received by May 1, 1994.  Notification of acceptance or
rejection will be mailed to applicants by May 15, 1994.

A set of working notes will be distributed at the workshop.  Camera
ready copies of papers accepted for inclusion in the working notes of
the workshop will be due on June, 15, 1994.

The timetable is as follows:

        Abstracts, papers, etc due to chair             1 May
        Decisions made, submitters get feedback        15 May
        Final working-note submissions rcv'd by chair  15 June
        workshop date                                  10 July, 1994


Please send one copy to each organizer:

Michiel Noordewier
Department of Computer Science
Rutgers University
Hill Center; Busch Campus
New Brunswick, NJ 08903

Lindley Darden
The Rockefeller University
c/o Lederberg Lab; Box 174
1230 York Avenue
NY, NY l0021-6399
(212) 327-7812
(212) 327-8651 (fax)  
darden@umiacs.umd.edu

This workshop is being held in conjunction with  

            ML '94                             COLT '94

  Eleventh International Conference        Seventh ACM Conference on
         on Machine Learning             Computational Learning Theory
          July 10-13, 1994                     July 12-15, 1994
 


For general registration and housing information, please contact 
Priscilla Rasmussen (rasmussen@cs.rutgers.edu; 908-932-2768).

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***************************************************************** 
General Announcement and Registration Information for the 

          Second International Conference on
       INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY 
                      (ISMB-94)

                   August 14-17, 1994
                  Stanford University
                 Stanford, California
                 Fairchild Auditorium

PURPOSE

The Second International Conference on Intelligent Systems for Molecular
Biology (ISMB) will take place at Stanford University, Palo Alto,
California on August 14-17, 1994. The ISMB conference is intended to bring
together scientists who are applying the technologies of advanced data
modeling, machine learning, artificial intelligence, robotics, parallel
computing, and other computational methods to problems in molecular
biology. The scope extends to any computational or robotic system
supporting a biological task that is cognitively challenging, involves a
synthesis of information from multiple sources at multiple levels, or in
some other way exhibits the abstraction and emergent properties of an
"intelligent system." 

Last year's conference in Bethesda, MD attracted an overflow crowd, yielded
a diverse offering of papers, invited speakers, posters and tutorials,
provided an exciting opportunity for researchers to meet and exchange
ideas, and was an important forum for the developing field. We are
continuing the tradition of pre-published, rigorously refereed proceedings,
and opportunities for fruitful personal interchange. 

The four-day conference will feature introductory and advanced
tutorials (on August 14), and presentations of original refereed papers
and invited talks (on August 15-17).  A preliminary program including 
original papers will be distributed in early May.  Tutorials are 
described below.

The conference will be held at:

Fairchild Auditorium
Stanford University Medical Center
Stanford, California

Stanford is in the San Francisco Bay area, approximately 25 minutes south
of San Francisco International Airport and approximately 25 minutes north
of San Jose International Airport. 

Limited funds are available to support travel to ISMB-94 for students and
post-docs, as well as for women and minority scientists.  Applications are
available by contacting ismb@camis.stanford.edu or using the mailing
address given below. 

ORGANIZING COMMITTEE
Russ Altman,            Stanford University
Doug Brutlag,           Stanford University
Peter Karp              SRI
Richard Lathrop         MIT
David Searls            U. of Pennsylvania

PROGRAM COMMITTEE
K. Asai                 ETL, Tsukuba
D. Benson               NCBI, Bethesda
B. Buchanan             U of Pittsburgh
C. Burks                LANL, Los Alamos
S, Brunak               DTN, Lyngby, Denmark
D. Clark                ICRF, London
F. Cohen                UCSF, San Francisco
T. Dietterich           OSU, Corvallis
S. Forrest              UNM, Albuquerque
J. Glasgow              Queen's U., Kingston
P. Green                Wash U, St. Louis
M. Gribskov             SDSC, San Diego
D. Haussler             UCSC, Santa Cruz
S. Henikoff             FHRC, Seattle
L. Hunter               NLM, Bethesda
T. Klein                UCSF, San Francisco
A. Lapedes              LANL, Los Alamos
M. Mavrovouniotis       Northwestern U
G. Michaels             George Mason U, Fairfax
G. Myers                U. Arizona, Tucson
K. Nitta                ICOT, Tokyo
C. Rawlings             ICRF, London
J. Sallatin             LIRM, Montpellier
C. Sander               EMBL, Heidelberg
J. Shavlik              U Wisconsin, Madison
D. States               Wash U, St. Louis
G. Stormo               U Colorado, Boulder
E. Uberbacher           ORNL, Oak Ridge
M. Walker               Stanford U, Stanford
T. Webster              Stanford U, Stanford
X. Zhang                PHZ Parnters, Cambridge


PROCEEDINGS:
Full-length papers from both talks and posters will be published in
archival proceedings. Copies will be distributed at the conference to
registered attendees, and extra copies will be available for purchase from
the publisher subsequently. The citation is: 

Proceedings of the Second International Conference on Intelligent Systems
for Molecular Biology (eds. R. Altman, D. Brutlag, P. Karp, R. Lathrop and
D. Searls) AAAI Press, Menlo Park CA, 1994. 

In addition to covering the cost of the proceedings, the registration fee
covers refreshments and general program expenses. 

TUTORIALS:

All tutorials will be offered on Sunday, August 14. There will be parallel
sessions geared for introductory issues and advanced issues. Tutorials
costs are $50 for a single tutorial and $70 for two tutorials.


AM Tutorials (August 14, 1994, 9:00 AM - 12:00 PM)

Introductory AM Tutorials:

         T1. INFORMATION SCIENCE FOR MOLECULAR BIOLOGISTS.              
                Dr. Douglas Brutlag (Stanford University)
                will provide an introduction to and overview of
                the methods of information science particularly
                relevant to molecular biology. These include
                multiple representations, machine learning, search
                and constraint methods, sequence analysis techniques,
                and pattern matching, with specific examples.

         T2. MOLECULAR BIOLOGY FOR COMPUTER SCIENTISTS.
                Dr. Gary Stormo (University of Colorado, Boulder)
                will provide an introduction to and overview of
                the basic concepts of modern molecular biology
                particularly relevant to computational methods.
                These include the fundamentals of DNA, RNA and
                protein sequences, their structures and functions,
                concepts of homology and phylogenetic relationships,
                and basic cell biology and metabolism. In addition,
                information will be provided about experimental methods,   
                databases, and the genome project.

     Advanced AM Tutorials:

         T3. MINIMAL LENGTH ENCODING IN MOLECULAR BIOLOGY.                 
             
                Dr. Aleksandar Milosavljevic (Argonne National
                Laboratory) will introduce the minimal length
                encoding (MLE) method to computational biologists
                who are designing sequence analysis algorithms, to
                computer scientists who are in interested in learning
                more about macromolecular sequence analysis, and to
                biologists who are more advanced users of sequence
                analysis programs. The emphasis will be on the use of
                the MLE method as a tool for comparative analysis.


         T4. MACHINE LEARNING APPROACHES IN COMPUTATIONAL MOLECULAR             
                BIOLOGY. Dr. Pierre Baldi (California Institute of         
                Technology) will provide an introduction to the basic
                machine learning methods often used in sequence analysis:
                including hidden markov models,  neural networks,
                the Bayesian framework and maximum likelihood estimation, 
                model fitting and model classes, learning and optimization 
                algorithms, and applications.  (This tutorial is the first
                of a two-part sequence with T9.  The cost for T4
                and T9 is $70.)

PM Tutorials (August 14, 1994, 1:30 PM to 4:30 PM)

    Introductory PM Tutorials:

        T5.  COMPUTATIONAL CHALLENGES FOR INTELLIGENT SYSTEMS IN        
                MOLECULAR BIOLOGY. Drs. Russ Altman (Stanford University)
                and Peter Karp (SRI) will provide a breadth first survey
                of important application areas within ISMB, and discuss
                outstanding accomplishments and challenges. Topics will    
                include biological databases, sequence analysis, protein  
                and nucleic acid structure prediction, signal to symbol    
                transformations, molecular evolution, metabolic pathways,  
                and machine learning. (T1 or T2 or equivalent recommended)

        T6.  NEURAL NETWORKS
                Dr. David Bisant (Stanford University)
                will teach the basics of neural network models.
                The session will also highlight the application
                of neural networks to sequence analysis and other
                problems in molecular biology. The tutorial will start
                with the most basic concepts and proceed from there.

    Advanced PM Tutorials:

        T7.  CONSTRAINT SATISFACTION IN MOLECULAR BIOLOGY.              
                Drs. Christopher Rawlings and Dominic Clark
                (Imperial Cancer Research Fund) will show how
                a wide variety of biological problems, especially those
                with very large hypothesis spaces, can be formulated
                as constraint satisfaction problems. They will discuss
                solution methods for constraint satisfaction
                problems using ideas (such as search, optimization and
                network consistency) from classical artificial
                intelligence as well as more recent developments
                from related disciplines.

        T8. GENETIC ALGORITHMS AND GENETIC PROGRAMMING.                    
            
                Dr. John Koza (Stanford University)
                will introduce the genetic algorithm, an
                increasingly popular approach to highly non-linear
                multidimensional optimization problems, that was
                originally inspired by a biological metaphor. This
                tutorial will cover both the biological motivations, and
                the actual implementation and characteristics of the
                algorithm. Genetic programming (an extension for
                problems in which the size and shape of the solution
                is a major part of the problem) will also be addressed.

        T9. HOW TO USE HIDDEN MARKOV MODELS, STOCHASTIC                    
                CONTEXT-FREE GRAMMARS AND OTHER RELATED MODELS
                Dr. David Haussler (U.C. Santa Cruz)
                will provide a solid foundation in the use of hidden
                Markov and related statistical models, including theory
                and key algorithms, the time series model, stochastic
                graph grammars, segment models, practical issues and
                limitations, and detailed examples of biological   
                applications.  (This tutorial is the second of a two-part 
                sequence with T4.  The cost for T4 and T9 is $70.)

HOUSING AND MEAL PLANS

Accommodations are available for the conference at the Governor's Corner
student housing facility on Stanford's Campus (corner of Santa Teresa St.
and Campus Drive West). The housing facility and dining room are a 10 to 15
minute walk from the main conference venue, Fairchild Auditorium. A special
combined room and board rate has been negotiated with the conference
center. By conference center policy, it is not possible for attendees to
make reservations for a room alone, without meals. The food provided at
Governor's Corner receives excellent reviews and is considered to be a
"deluxe" service. Room and board reservations must be made by July 19,
1994. 

Note: The conference will last the entire day of Wednesday, August 17, and
so checkout from conference facilities is scheduled for the morning of
Thursday, August 18.

There are two packages available for out of town participants: 

1A. Arrival on Saturday, August 13, with checkout on morning of 
Thursday, August 18. Breakfast, lunch and dinner provided for August 14
through August 17. 

   Single occupancy packaged price is $455 
   Double occupancy packaged price is $392  

1B. Arrival on Sunday, August 14, with checkout on morning of 
Thursday, August 18. Breakfast, lunch and dinner provided for August 15
through August 17. 

   Single occupancy packaged price is $352 
   Double occupancy packaged price is $302  

There are two lunch packages for participants who are commuting to the
conference. These will take place in Governor's corner facility, during

2A. Lunches on Sunday, August 14 through 
    Wednesday, August 17, (Price: $75)
2B. Lunches on Monday, August 15 through 
    Wednesday, August 17. (Price: $57)

Return Registration Form (with payment) to 

ISMB-94
c/o Russ Altman
Section on Medical Informatics
SUMC, MSOB X-215
Stanford, CA 94305-5479
USA

For questions: ismb@camis.stanford.edu
       or Fax: (415) 725-7944

CUT HERE:
************************************************************* ISMB-94
REGISTRATION FORM:

Name:__________________________________________________ 

Affiliation: __________________________________________ 

Address:_______________________________________________ 

_______________________________________________ 

_______________________________________________ 

Phone: ___________________ Fax: ____________________ 

Email: _____________________________________________ 

Status: ________ Student _______ Non-student
            
        ________ Male    _______ Female

_____  Check if you would like information about travel support.


>Registration (Early = before 7/15)......................$_______ 

                  Early      Late
Non-student       $100       $125
Student            $75       $100


>Tutorials (select one or two tutorials).................$_______ 

                   One     Two
Regular            $50     $70
Student            $25     $35

AM 8/14:
__ T1: Information Science for Molecular Biologists 
__ T2: Molecular Biology for Computer Scientists 
__ T3: Minimal Length Encoding in Molecular Biology 
__ T4: Machine Learning in Molecular Biology 

PM 8/14:
__ T5: Computational Challenges for ISMB 
__ T6: Neural Networks
__ T7: Constraint Satisfaction in Molecular Biology 
__ T8: Genetic Algorithms and Genetic Programming 
__ T9: Hidden Markov Models, SCFGs, and Related Models 


>Room/Board (see detailed descriptions)..................$_______ 

         Single Occupancy         Double Occupancy
___1A.    $455                 $392
___1B.    $352                 $302

___2A. Lunch only, 8/14-8/17 $75
___2B. Lunch only, 8/15-8/17 $57

>>Total (Check or money order $US made to ISMB-94)... ...$_______




Doug Brutlag                             (415) 723-6593
Department of Biochemistry               (415) 328-7837  FAX
Beckman Center, B400                     brutlag@cmgm.stanford.edu
Stanford University School of Medicine                   
Stanford, California 94305-5307

