From owner-biophysics@net.bio.net Mon Mar 02 22:00:00 1998 Path: biosci!agate!howland.erols.net!news-peer.gip.net!news.gsl.net!gip.net!newshub1.home.com!news.home.com!news.rdc1.md.home.com!not-for-mail From: cweiss1@gl.umbc.edu (Christopher Weiss) Newsgroups: bionet.biophysics Subject: Boltzman probablility Date: Tue, 03 Mar 1998 04:11:41 GMT Organization: @Home Network Lines: 9 Message-ID: <34fb81e3.16669396@news> NNTP-Posting-Host: cc907278-a.catv1.md.home.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Newsreader: Forte Agent 1.5/32.451 What form of the Boltzman distribution equation should I use if I want to know the probability of finding a molecule with a particular potential energy? For example, I have a conformation of a protein and I can calculate its potential energy, what is the probability of the protein occuring with that energy? Thanks, Christopher Weiss From owner-biophysics@net.bio.net Mon Mar 02 22:00:00 1998 Path: biosci!agate!howland.erols.net!news-peer.gip.net!news-dc.gip.net!news.gsl.net!gip.net!news.belnet.be!news.rediris.es!news-2.rediris.es!news.uam.es!newsmasters From: Daniel Duque Newsgroups: bionet.biophysics Subject: Re: Boltzman probablility Date: Tue, 03 Mar 1998 11:23:47 +0000 Organization: UAM Lines: 12 Message-ID: <34FBE843.C7E6C34@fluid5.fmc.uam.es> References: <34fb81e3.16669396@news> NNTP-Posting-Host: fluid6.fmc.uam.es Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.04Gold (X11; I; Linux 2.0.33 i586) Christopher Weiss wrote: > > What form of the Boltzman distribution equation should I use if I want > to know the probability of finding a molecule with a particular > potential energy? For example, I have a conformation of a protein and > I can calculate its potential energy, what is the probability of the > protein occuring with that energy? Isn't it just exp(-E/(k T)), E=energy, k=B. constant, T=temperature? -- Daniel Duque Campayo -- daniel@fluid5.fmc.uam.es (no "x") From owner-biophysics@net.bio.net Mon Mar 02 22:00:00 1998 Path: biosci!EMS.HRBMU.EDU.CN!liucr From: liucr@EMS.HRBMU.EDU.CN (changrong liu) Newsgroups: bionet.biophysics Subject: Recruiting Papers for First International Disability Medicine Conference Date: 3 Mar 1998 09:05:37 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 102 Sender: daemon@net.bio.net Distribution: world Message-ID: <34FC373A.4C06@ems.hrbmu.edu.cn> Reply-To: liucr@ems.hrbmu.edu.cn NNTP-Posting-Host: net.bio.net Recruiting Papers for First International Disability Medicine Conference The disability medicine is a newly emerging subject. It includes the prevention, research, diagnosis, treatment, rehabitation, and nursing of all diseases causing by limbers and organs defects and severe malfunction of limbers, organs and psychology, which result from various factors of trauma and diseases. The wide contents of speciality include: preventive medicine, clinical medicine and rehabitation medicine. The disability medicine has just begun. In order to develop the academic exchange of the disability medicine, improve the research level and rehabitative level of the disability medicine, advance the development of the disability medicine, so that we can serve the patients better, serve the society better, we decided to hold "First International Disability Medicine Conference" in the capital of China -Beijing on August 8th, 1998. The meeting was co-organized by "The Chinese Rehabitation Association for disability medicine" and " The house of Journal of the disability medicine". 1. We recruit papers about: a. Disease Prevention b. The basic disease research c. Diagnosis, treatment, rehabitation and nursing of disease d. The research and application of apparatus and artificial limbers 2. People who can attend the meeting include: a. international administrative and technical staffs of disability medicine. b. The leader of Chinese hygiene division, the leaders of Chinese Rehabitation Association, the leaders, administrative staffs and technical staffs working on the rehabitation of disabled patients in the national and endemic disability association, red cross association and political administrative office. c. The technical staffs working on the prevention, research, medical treatment and nursing of diseases (all clinical operative specialities: osteology, brain surgery, cardiothoracic surgery, urinary surgery, orthopedics of burn, general surgery, pediatrics surgery, ophthalmology, otorhinol aryngology, stomatology, gynecology, tumorigenesis, anesthetics, etc. Non-operative specialities: internal medicine, neurology, psychiatry, etc.) , working on medical techniques (All specialities of diagnosis), physical rehabitative therapy (physical therapy, body therapy, acupuncture, massotherapy). d. The leaders and technical staffs working on the treatment of disability, rehabitative apparatus, research, exploitation and application of artificial limb and artificial prosthesis. 3. Guide lines for papers: a. The paper should be about 3,000 words, together with an abstract less than 500 words. (If possible, the paper and the abstract should be submitted with their corresponding English translation ) written on. paper. b. The accepted papers and abstracts of the meeting will be exchanged as meeting materials at the meeting, the authors will be informed the material fee by mail after the acceptance of the papers. 4. How to attend the meeting: People can apply since we inform the meeting. People who want to attend the meeting can mail their papers, the registration cards and fees for reviewing papers (£¤30 per paper, papers without the fee will not be reviewed) to Dr. Changrong Liu -- Header of the Hei longjiang paralysis institute in Harbin Medical University (Zip:150086). "papers for meeting" should be marked on the down left side of the envelope. See the definite time and place of the meeting on the formal information. The Chinese rehabitation association for Disability Medicine The house of Journal of disability medicine December 8th, 1997 Guidelines for Abstracts and papers The entire abstract should be about 500 words and paper should be typed on a typewriter in black ink about 3000 words, must be submitted in English. Papers will be received in May 31, 1998 (for acceptance in June 1998). Send the original and two copies of the typed paper together with completed submission form to : International Disability Medicine Conference Dr. Changrong Liu 157 Bao jian Street Harbin Medical University Disability Medicine Editorial Staff Habin, 150086 P. R. China Tel: +86-451-6669485 Fax: +86-451-6669470 E-mail: liucr@ems.hrbmu.edu.cn Registration International Disability Medicine Conference August 8-12, 1998 Please print or type Clearly First name: Middle: Last name: Tittle: Employer: Affiliation: Business Address: City: Country: Zip code: Tel: Fax: E-mail: MAIL TO : International Disability Medicine conference Dr. Changrong Liu 157 Bao Jian Street Harbin Medical University Disability Medicine Editorial Staff Harbin 150086 P. R. China From owner-biophysics@net.bio.net Tue Mar 03 22:00:00 1998 Path: biosci!agate!howland.erols.net!news.idt.net!woodstock.news.demon.net!demon!news.demon.co.uk!demon!luke1017.demon.co.uk!not-for-mail From: "Nigel Dyer" Newsgroups: bionet.biophysics Subject: Experiments to monitor the effect of 1000 GHz radiation Date: Tue, 3 Mar 1998 22:31:01 -0000 Message-ID: <889052673.2558.1.nnrp-11.c2de40bb@news.demon.co.uk> NNTP-Posting-Host: luke1017.demon.co.uk X-NNTP-Posting-Host: luke1017.demon.co.uk [194.222.64.187] X-Newsreader: Microsoft Outlook Express 4.72.2106.4 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.2106.4 Lines: 13 I want to investigate the effect of electromagnetic radiation at various spot frequencies around 1000GHz (microwave/infrared frequencies) on the activity of certain proteins. Does anyone have any experience of performing similar experiments, or know of suitable spot frequency (preferably tunable) low intensity electromagmetic radiation sources that operate at about this frequency Thanks Nigel From owner-biophysics@net.bio.net Wed Mar 04 22:00:00 1998 Path: biosci!agate!newsgate.duke.edu!nntprelay.mathworks.com!newsfeed.internetmci.com!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: prismx@scienceweek.com (Claire Haller) Newsgroups: bionet.neuroscience,bionet.biophysics,bionet.cellbiol,bionet.general,sci.misc Subject: SCIENCE-WEEK: Headlines (6 Mar 98) Date: Thu, 05 Mar 1998 18:08:31 GMT Organization: SCIENCE-WEEK Lines: 54 Message-ID: <6dmpng$plt@ecuador.earthlink.net> Reply-To: prismx@scienceweek.com NNTP-Posting-Host: 153.35.114.234 X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.neuroscience:21539 bionet.biophysics:4048 bionet.cellbiol:9004 bionet.general:29499 SCIENCE-WEEK is a free weekly Email digest of the news of science read each week by 50,000+ people in the scientific community in more than 40 countries. News briefs from the major journals are amplified with enough background material to make them intelligible to nonspecialists: the biology is detailed for physicists and chemists, and the physics and chemistry are detailed for biologists. Each issue contains 15 to 20 news reports, annotated listings of new books in the sciences, a Positions Available section, and other notices of interest to science professionals. The SW complete weekly news reports are available free via Email. To subscribe, send SUB SW to . Contents of the Latest Issue Mar 6, 1998: 1. Present and Future US Physics PhDs Discouraged by Lack of Jobs 2. On the Role of Science in Developing Countries 3. On Irregular Arrays and Randomization 4. Magnetic-Electric Aharonov-Bohm Effect in Metal Rings 5. Direct Observation of Heterogeneous Atmosphere Chemistry 6. Global Warming: On Errors in Predicting Species Range Shifts 7. Use of Coulomb Explosion to Observe Femtosecond Reactions 8. Using DNA as a Template for Assembling a Wire Connection 9. A Study of Protein Hydration in the Gaseous Phase 10. A Mathematical Model of Dynamical Principles in Bio-Processes 11. A Unified View of Polymer Nearest-Neighbor Thermodynamics 12. Single Secretory Vesicles Probed by Capillary Electrophoresis 13. Genetic Interference by Double-Stranded RNA in C. Elegans 14. Targeted Mutagenesis by Peptide Nucleic Acids 15. Collapse of Plasmid DNA into Stable Virus-Like Particles 16. Bcl-2 Prevents Apoptosis by Proton Flux Regulation 17. Use of Caged Peptides to Reveal Cell Signaling Pathways 18. Malaria: Genetics of Host-Parasite Coevolution 19. On Cellular Responses to Interferons and Other Cytokines 20. Farnesyl Transferase Inhibitors as Anti-Tumor Agents Book Notes Notices - Positions Available Notices - Miscellaneous SCIENCE-WEEK is a free retransmission educational resource, which means this headline notice and each issue of SCIENCE-WEEK itself can be retransmitted if intact by any installation. All back issues of SCIENCE-WEEK are available at the URL below. Current issues are posted at the URL 2 to 5 days after first publication. The Editors SCIENCE-WEEK A Free Weekly Digest of the News of Science editors@scienceweek.com http://scienceweek.com From owner-biophysics@net.bio.net Wed Mar 04 22:00:00 1998 Path: biosci!agate!logbridge.uoregon.edu!arclight.uoregon.edu!news-out.internetmci.com!newsfeed.internetmci.com!164.67.42.145!awabi.library.ucla.edu!164.67.80.81!news.ucla.edu!wlheye.jsei.ucla.edu!lukasz From: lukasz@wlheye.jsei.ucla.edu (Lukasz Salwinski) Newsgroups: bionet.biophysics Subject: Re: Many Q Date: 5 Mar 1998 17:13:35 GMT Organization: Jules Stein Eye Institute, UCLA Lines: 11 Distribution: world Message-ID: <6dmmfv$rnc$1@uni.library.ucla.edu> References: <34fe58cb.774984@news.netvigator.com> <6dlnk2$s01$1@vixen.cso.uiuc.edu> NNTP-Posting-Host: wlheye.jsei.ucla.edu X-newsreader: xrn 9.00 -- >Concerning mjts@usa.net's questions: > [...] >P.S. > Don't post class assignments to newsgroups. fortunately, no damage this time... both answers are wrong ;o) l From owner-biophysics@net.bio.net Wed Mar 04 22:00:00 1998 Path: biosci!agate!howland.erols.net!fastnet!uunet!in1.uu.net!whowhere.com!nntp.csuchico.edu!waldorf.csc.calpoly.edu!nntp-server.caltech.edu!shf From: shf@cco.caltech.edu (Simon H. Friedman) Newsgroups: bionet.biophysics Subject: Re: Boltzman probablility Date: 5 Mar 1998 08:48:38 GMT Organization: California Institute of Technology, Pasadena Lines: 23 Message-ID: <6dlot6$er@gap.cco.caltech.edu> References: <34fb81e3.16669396@news> <34FBE843.C7E6C34@fluid5.fmc.uam.es> NNTP-Posting-Host: accord.cco.caltech.edu In article <34FBE843.C7E6C34@fluid5.fmc.uam.es>, Daniel Duque wrote: >Christopher Weiss wrote: >> >> What form of the Boltzman distribution equation should I use if I want >> to know the probability of finding a molecule with a particular >> potential energy? For example, I have a conformation of a protein and >> I can calculate its potential energy, what is the probability of the >> protein occuring with that energy? > >Isn't it just exp(-E/(k T)), E=energy, k=B. constant, T=temperature? > Its proportional to that. The actual probability (i.e. range from 0-1) is that factor divided by the sum of the same factors for every possible configuration of the system. p(sub i)= exp(-Ei/kT)/sigma_over_all_i(E/kt) Actually figuring out what those values are is another problem! Simon From owner-biophysics@net.bio.net Wed Mar 04 22:00:00 1998 Path: biosci!agate!howland.erols.net!vixen.cso.uiuc.edu!uiuc.edu!no-spam From: no-spam@uiuc.edu (Andrew) Newsgroups: bionet.biophysics Subject: Re: Many Q Date: 5 Mar 1998 08:26:42 GMT Organization: University of Illinois at Urbana-Champaign Lines: 13 Distribution: world Message-ID: <6dlnk2$s01$1@vixen.cso.uiuc.edu> References: <34fe58cb.774984@news.netvigator.com> NNTP-Posting-Host: ophelia.ks.uiuc.edu Concerning mjts@usa.net's questions: Q1: Since the pendulums differ in length but have the same density, the masses are different. More massive things are slower, so the longer pendulum is slower, which explains the difference. Q2: The bias level for the material is 200 e- for the given area. At this point the system is saturated, so no matter how much more light is shown onto it there will be no change in the amount of emissions. P.S. Don't post class assignments to newsgroups. From owner-biophysics@net.bio.net Wed Mar 04 22:00:00 1998 From: mjts@usa.net Newsgroups: bionet.biophysics Subject: Many Q Date: Thu, 05 Mar 1998 07:48:33 GMT Organization: Netvigator Lines: 12 Message-ID: <34fe58cb.774984@news.netvigator.com> Reply-To: mjts@usa.net NNTP-Posting-Host: yckam031003.netvigator.com X-Newsreader: Forte Free Agent 1.11/32.235 Path: biosci!agate!howland.erols.net!newsfeed.internetmci.com!202.84.255.3!news.hkt.net!news.netvigator.com!usenet Q1) Two simple pendulums X and Y differ slightly in length. When set swinging together, they gradually become out of step, but are back in step each time X completes 100 oscillations. The length of Y differs from that of X by approximately 1 part in 50. Why? Please explain in details. Q2) When a beam of light of intensity I and frequency f is shone on the surface of a metal connected to earth, 200 electrons are rejected from the surface per second. If a light beam of intensity 2I and frequency 2f is used, the number of electrons ejected from the metal per second will be still 200. Why? Please explain in details. From owner-biophysics@net.bio.net Thu Mar 05 22:00:00 1998 Path: biosci!agate!newsfeed.kornet.nm.kr!nntp.kreonet.re.kr!logbridge.uoregon.edu!news.bc.net!news.sfu.ca!beaufort!rstorjoh From: Rasmus Storjohann Newsgroups: bionet.biophysics Subject: Lipari/Szabo calculations Date: Fri, 6 Mar 1998 11:39:25 -0800 Organization: Simon Fraser University Lines: 54 Message-ID: NNTP-Posting-Host: beaufort.sfu.ca Mime-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII X-Sender: rstorjoh@beaufort I want to use relaxation matrix refinement and the Lipari-Szabo model-free approach to improve my under-defined NMR structure. This means that I need numbers for my correlation time and my order parameter. I was planning to get my correlation time either from T1 relaxation at two different field strengths, or from publinshed data based on Trp fluorescence. (The correlation time from fluorescence is the correlatioin time of overall motion, while the correlation time from T1 relaxation is the correlation time of overall+internal motion, is that right?) I have preliminary structures calculated by distance geometry and restrained molecular dynamics. These structures have more and less well defined regions, which should correspond to some extent to more and less flexible regions of the peptide in solution. I was thinking that if I could calculate the order parameter based on my preliminary structures, the relaxation matrix calculations should have a pretty accurate motional model to start from. X-plor allowes the specification of different order-parameters (and different correlation times) between different parts of the molecule, e.g.: taucorrel DMSO model lipari vector (name hn or name ha) (name hn or name ha) 0.75e-9 0.85 vector (name hn or name ha) (name h* and not (name hn or name ha)) 0.75e-9 0.80 vector (name h* and not (name hn or name ha)) (name h* and not (name hn or name ha)) 0.75e-9 0.65 end giving a uniform correlation time of 0.75ns, and order parameters of 0.85 for backbone-to-backbone, 0.80 for backbone-to-sidechain, and 0.65 for sidechain-to-sidechain. I'm using the molecular visualisation program MolMol, which allowes me to calculate order parameters for all the dihedral angles of the molecule. Is there any way I can convert these order parameters to the ones seemingly related to inter-proton distances required for X-plor? Thanks for your patience! Rasmus ____________________________________________________________________ __ Rasmus Storjohann / /\ Institute of Molecular Biology / / \ and Biochemistry / / /\ \ Simon Fraser University / / /\ \ \ Burnaby, British Columbia V5A 1S6 / /_/__\ \ \ e-mail: rstorjoh@sfu.ca /________\ \ \ Phone: (604) 291-5657 / 415-0575 \___________\/ FAX: (604) 291-3765 From owner-biophysics@net.bio.net Thu Mar 05 22:00:00 1998 Path: biosci!agate!logbridge.uoregon.edu!news-peer.gip.net!news.gsl.net!gip.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!worldnet.att.net!news.u.washington.edu!fujimoto From: fujimoto@u.washington.edu (Bryant Fujimoto) Newsgroups: bionet.biophysics Subject: Re: Lipari/Szabo calculations Date: 6 Mar 1998 21:01:30 GMT Organization: University of Washington Lines: 19 Message-ID: <6dpo7a$mso$1@nntp3.u.washington.edu> References: NNTP-Posting-Host: homer23.u.washington.edu X-Trace: nntp3.u.washington.edu 889218090 23448 (None) 140.142.64.6 X-Complaints-To: help@cac.washington.edu NNTP-Posting-User: fujimoto Rasmus Storjohann writes: >I want to use relaxation matrix refinement and the Lipari-Szabo >model-free approach to improve my under-defined NMR structure. This means >that I need numbers for my correlation time and my order parameter. I was >planning to get my correlation time either from T1 relaxation at two >different field strengths, or from publinshed data based on Trp >fluorescence. (The correlation time from fluorescence is the correlatioin >time of overall motion, while the correlation time from T1 relaxation is >the correlation time of overall+internal motion, is that right?) Any internal motion which the Trp undergoes will be reflected in its correlation times. Also, if the molecule is not spherical, then the correlation times will depend on the orientation of the Trp or the relative positions of the nuclei in the molecule. Bryant Fujimoto fujimoto@u.washington.edu From owner-biophysics@net.bio.net Fri Mar 06 22:00:00 1998 Path: biosci!rutgers!gatech!141.211.144.13.MISMATCH!newsxfer3.itd.umich.edu!news.maxwell.syr.edu!news.mel.connect.com.au!news.syd.connect.com.au!ns.dot.net.au!vulcan From: geoffhys@f1.net.au (Geoff Heyes) Newsgroups: bionet.biophysics Subject: ethics homepage - advert.html [01/01] Date: Sat, 07 Mar 98 19:10:31 GMT Organization: Dot Communications Ltd, Australia, +612 9281-1111 Lines: 24 Message-ID: <6dq415$s8v$3@ns.dot.net.au> NNTP-Posting-Host: dialup-010.f1.net.au X-Newsreader: News Xpress 2.0 Beta #2 begin 644 advert.html M/$A434P^#0H\2$5!1#X-"CQ-151!($A45%`M15%5258](D-O;G1E;G0M5'EP M92(@0T].5$5.5#TB=&5X="]H=&UL.R!C:&%R65S/"]0/@T*/"]&3TY4/CQ&3TY4(%-)6D4] M,CX\4#XF;F)S<#L\+T9/3E0^/$$@2%)%1CTB:'1T<#HO+W=W=RYG96]C:71I M97,N8V]M+U)A:6Y&;W)E Reply-To: n¤c¤o¤r¤p@s¤l¤a¤v¤e¤c¤a¤m¤p.a¤d¤l NNTP-Posting-Host: 38.216.186.105 X-Newsreader: Forte Free Agent 1.11/32.235 On Sun, 8 Mar 1998 20:23:25 -0000, the eminent natural philosopher "Aron" formulated yet another of his myriad comprehensive principles summarizing life, the universe, and everything: >> >>> BTW, if you look at the sci.physics..... newsgroup, you will see >>>many posters contesting the official science, especially Einstenian >>>relativity. My personnal feeling is: most twentieth century physics is >>>a big lie and is maintained by "respected " scientists who don't want >>>to see the work of their life contested by innovative scientists! >> >The above is rubbish. There are two branches of physics. One which was >expounded by people like Newton and Einstein and then there is Quantum >mechanics which is very different. It is here where many innovations lie. >This is the future regarding spcae travel and the supersoul, this will prove >it. Proof that there is a soul overlooking the universe and incarnate as >godhead in all living things should banish us of repressive religion. > ncorp admires Aron’s unrivaled expertise in virtually every branch of physics that is known to man! Gee Aron, surely, you do impress us all! tee hee hee hee hee hee hee hee hee hee hee hee hee hee hee hee hee... ——ncorp From owner-biophysics@net.bio.net Sun Mar 08 22:00:00 1998 Path: biosci!TELEPORT.COM!spiegel From: spiegel@TELEPORT.COM (Steve Spiegel) Newsgroups: bionet.biophysics Subject: (none) Date: 8 Mar 1998 20:21:28 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 2 Sender: daemon@net.bio.net Distribution: world Message-ID: <199803090420.UAA14256@mail1.teleport.com> NNTP-Posting-Host: net.bio.net subscribe steve spiegel From owner-biophysics@net.bio.net Sun Mar 08 22:00:00 1998 Path: biosci!agate!spool.mu.edu!uwm.edu!news-penn.gip.net!news-peer.gip.net!news.gsl.net!gip.net!news.maxwell.syr.edu!news2.chicago.iagnet.net!qual.net!iagnet.net!146.186.130.59!news.math.psu.edu!ra.nrl.navy.mil!not-for-mail From: David Schaafsma Newsgroups: bionet.biophysics Subject: Re: Many Q Date: Mon, 09 Mar 1998 14:14:07 -0500 Organization: Naval Research Laboratory, Washington, DC Lines: 22 Message-ID: <35043F7F.81FDEF0A@jnpcs.com> References: <34fe58cb.774984@news.netvigator.com> <6dlnk2$s01$1@vixen.cso.uiuc.edu> Reply-To: drdave@jnpcs.com NNTP-Posting-Host: elvis.nrl.navy.mil Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.03 [en] (Win95; U) > Concerning mjts@usa.net's questions: > Q1: > Since the pendulums differ in length but have the same density, the masses > are different. More massive things are slower, so the longer pendulum is > slower, which explains the difference. > > Q2: The bias level for the material is 200 e- for the given area. At this > point the system is saturated, so no matter how much more light is shown > onto it there will be no change in the amount of emissions. > > P.S. > Don't post class assignments to newsgroups. Excellent job - let's just hope he learns something when he gets an F on his homework assignment. _______________________ All opinions my own, not my employer's, etc. From owner-biophysics@net.bio.net Wed Mar 11 22:00:00 1998 Path: biosci!agate!newsfeed.wli.net!news-out.internetmci.com!newsfeed.internetmci.com!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: prismx@scienceweek.com (Claire Haller) Newsgroups: bionet.neuroscience,bionet.biophysics,bionet.cellbiol,bionet.general,sci.misc Subject: SCIENCE-WEEK: Headlines (13 Mar 98) Date: Thu, 12 Mar 1998 14:51:56 GMT Organization: SCIENCE-WEEK Lines: 54 Message-ID: <6e8sqv$do5@argentina.earthlink.net> Reply-To: prismx@scienceweek.com NNTP-Posting-Host: 153.35.114.207 X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.neuroscience:21589 bionet.biophysics:4057 bionet.cellbiol:9033 bionet.general:29540 SCIENCE-WEEK is a free weekly Email digest of the news of science read each week by 50,000+ people in the scientific community in more than 40 countries. News briefs from the major journals are amplified with enough background material to make them intelligible to nonspecialists: the biology is detailed for physicists and chemists, and the physics and chemistry are detailed for biologists. Each issue contains 15 to 20 news reports, annotated listings of new books in the sciences, a Positions Available section, and other notices of interest to science professionals. The SW complete weekly news reports are available free via Email. To subscribe, send SUB SW to . Contents of the Latest Issue Mar 13, 1998: 1. New Evidence for a Cosmic Antigravity Force 2. Cosmic X-Ray Background: Contribution of Faint Galaxies 3. An Oxygen-Rich Stellar Dust Disk in the Red Rectangle 4. Dephasing in Electron Interference by a Which-Path Detector 5. Electrophoresis in Lyotropic Polymer Liquid Crystals 6. Molten Globules as a Third Phase of Proteins 7. Pressure Dependence of Hydrophobic Interactions of Proteins 8. A Gene for Adhesion and Filamentous Growth in C. Albicans 9. Evidence of De Novo Insertion of an Intron into a Gene 10. New Drosophila Introns Originate by Duplication 11. A Protein that Protects Retroviral DNA Autointegration 12. New Antitumor Agent Arrests Metaphase and Induces Apoptosis 13. Molecular Characterization of a Neuronal Calcium Channel 14. Spatial Working Memory Localized in Human Frontal Cortex 15. Target-Specific Presynaptic Plasticity in Neurons 16. A New Type of Synaptic Plasticity of Neocortical Neurons 17. Herpes Virus Molecular Mimicry and Autoimmune Disease 18. An Insulin Receptor Substrate Implicated in Type 2 Diabetes 19. Evidence of Human Genetic Susceptibility to Tuberculosis 20. HIV Trials Controversy and Transmission in Pregnant Women Book Notes Notices - Positions Available Notices - Miscellaneous SCIENCE-WEEK is a free retransmission educational resource, which means this headline notice and each issue of SCIENCE-WEEK itself can be retransmitted if intact by any installation. All back issues of SCIENCE-WEEK are available at the URL below. Current issues are posted at the URL 2 to 5 days after first publication. The Editors SCIENCE-WEEK A Free Weekly Digest of the News of Science editors@scienceweek.com http://scienceweek.com From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!207.97.14.174!europa.clark.net!204.59.152.222!news-peer.gip.net!news.gsl.net!gip.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!newsfeed.nacamar.de!fu-berlin.de!jussieu.fr!uvsq.fr!not-for-mail From: Jerome Villanova Newsgroups: bionet.biophysics Subject: Re: Calc. Velocity of Falling Cows Date: Fri, 13 Mar 1998 11:26:50 +0100 Organization: Universite de Versailles/St Quentin en Yvelines - France Lines: 81 Message-ID: <350909E9.472BFE96@robot.uvsq.fr> References: <3507972c.7732046@news1.abac.com> NNTP-Posting-Host: mercure.robot.uvsq.fr Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.04 [en] (X11; I; SunOS 4.1.4 sun4m) Dave Irontail wrote: > Hiya! Hope you can help me. Our 9th grade teacher told us a true > story about cows that were stolen by a military plane crew, who, at an > altitude of 30,000 feet decided to allow the cows to run out and > plunge to the ocean below. One of these cows hit and sunk a fishing > boat. I got to wondering how to figure the power of the inmact. I > figure the cow weighs about 1500 lbs. > Thank you! > > DMIrontail > 14EEE@Bigfoot.com Do you allow me to use the metric system ? It was just a rethorical question anyway. :-) So, there are roughly three feet in a meter, so the starting altitude of the free-falling cows was about 10 000 m. A kg is 2.2 lbs therefore your basic cow weighs 700 kg. We have to make a few suppositions : -let's say the plane was flying horizontaly : thefore the initial falling speed of the cow will be 0 m/s. -let's say the cows have never even heard of sky-surfing and that they do not brake their fall by taking advantage of air resistance. What forces are exerted on the cow ? - only gravity : -g.Z where g=9.81 m/s^2 and Z the vertical axis originated on the ship and following the radius of the earth. So the force equilibrium can be writen in the form : m.(gamma) = -m.g where m is the mass of the cow, gamme it's acceleration. So gamma = -g. The speed of the cow is therefore speed = -gt + k where t is the time in seconds, and k a constant. At t=0, the vertical speed of the cow is 0 so k=0. speed = -gt. The position of the cow is pos = -(1/2).g.t^2 + l where l is a constant. at t = 0, the vertical position of the cow is 10 000 m so l =10 000. pos = -(1/2).g.t^2 + 10 000. The potential energy of the cow is Ep = m.g.pos = (700*9.81*10 000) = 68MJ (roughly) the cow touches the boat when p = 0. this means when (1/2).g.t^2 = 10 000. So, t(contact) = square_root (2* 10 000/ 9.81). t(contact)= 45 s (roughly). The cow as fallen for 45 seconds before hitting the boat. Its speed was at the moment : speed(contact) = -gt(contact). The magnitude of the speed at the instant of contact is therefore 440 m/s (1584 km/h) or 1300 ft/s. The quantity of movement of the cow is p = m.speed = 308 000 kg.m/s The kinetical energy of the cow at contact time is Ec = (1/2).m.v^2. Ec = 68 000 000 J = 68 MJ (roughly) = 16 000 kcal note that Ec at the end of the fall is equal to Ep at the start of it. Let's suppose the cow stops in one second after having hit the boat. The power generated by the shock is 68 MJ / 1 s = 68 MW. That's equivalent to the power of 680 000 100 watts light bulbs. It's a pretty nice flash. That cow could have sunk the Titanic. Of course, the best would have been crushing L DiCaprio and C Winsley. -- ------------------------------------ Jerome X Villanova E.mail: villa@robot.uvsq.fr ------------------------------------- From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!agate!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!newsfeed.internetmci.com!208.137.248.9!news1.abac.com!not-for-mail From: 14EEE@bigfoot.com (Dave Irontail) Newsgroups: bionet.biophysics Subject: Calc. Velocity of Falling Cows Date: Fri, 13 Mar 1998 00:25:16 GMT Organization: Eclipse Enterprises Lines: 10 Message-ID: <3507972c.7732046@news1.abac.com> NNTP-Posting-Host: sd-ppp-318.abac.net X-Newsreader: Forte Free Agent 1.11/32.235 Hiya! Hope you can help me. Our 9th grade teacher told us a true story about cows that were stolen by a military plane crew, who, at an altitude of 30,000 feet decided to allow the cows to run out and plunge to the ocean below. One of these cows hit and sunk a fishing boat. I got to wondering how to figure the power of the inmact. I figure the cow weighs about 1500 lbs. Thank you! DMIrontail 14EEE@Bigfoot.com From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!ljlbio.com!jowicki From: jowicki@ljlbio.com (Jack Owicki) Newsgroups: bionet.biophysics Subject: FW: Calc. Velocity of Falling Cows Date: 13 Mar 1998 08:52:16 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 49 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net I would think that it's not just a matter of size, but of the geometry of the bailing bovine. If I remember correctly, it's hard to calculate terminal velocities of highly asymmetric objects like disks because of chaotic tumbling. And they're not even flexible like a cow. All in all I think there's ample material here to write a proposal for a research contract from DARPA (the Defense-Department agency that funds blue-sky R&D of potential military application). Jack Owicki ---------- From: zauhar@elara.tripos.com [SMTP:zauhar@elara.tripos.com] Sent: Friday, March 13, 1998 7:28 AM To: biophys@net.bio.net Subject: Re: Calc. Velocity of Falling Cows The terminal velocity calculation is what's most interesting - is Stoke's law a reasonable approximation for something as big as a cow? I would think not.... Randy All opinions expressed here are mine, not my employer's /////////////////////////////////////////////////////////////////////// // \\ Randy J. Zauhar, PhD | E-mail: zauhar@tripos.com // \\ Tripos, Inc. | : zauhar@fastrans.net // \\ 1699 S. Hanley Rd., Suite 303 | Phone: (314) 647-1099 Ext. 3382 // \\ St. Louis, MO 63144 | // /////////////////////////////////////////////////////////////////////// // ** ** ** "If you have conceptions of things that you can have no conception ** ** of, then the conception and the thing appear to co-incide." ** ** --- C.G. Jung ** *********************************************************************** ** From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!elara.tripos.com!zauhar From: zauhar@elara.tripos.com Newsgroups: bionet.biophysics Subject: Re: Calc. Velocity of Falling Cows Date: 13 Mar 1998 07:28:06 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 19 Sender: daemon@net.bio.net Distribution: world Message-ID: <199803131524.JAA05679@xhost4> NNTP-Posting-Host: net.bio.net The terminal velocity calculation is what's most interesting - is Stoke's law a reasonable approximation for something as big as a cow? I would think not.... Randy All opinions expressed here are mine, not my employer's ///////////////////////////////////////////////////////////////////////// \\ Randy J. Zauhar, PhD | E-mail: zauhar@tripos.com // \\ Tripos, Inc. | : zauhar@fastrans.net // \\ 1699 S. Hanley Rd., Suite 303 | Phone: (314) 647-1099 Ext. 3382 // \\ St. Louis, MO 63144 | // ///////////////////////////////////////////////////////////////////////// ** ** ** "If you have conceptions of things that you can have no conception ** ** of, then the conception and the thing appear to co-incide." ** ** --- C.G. Jung ** ************************************************************************* From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!TTUHSC.EDU!phyan From: phyan@TTUHSC.EDU (Alan Neely) Newsgroups: bionet.biophysics Subject: Re: Calc. Velocity of Falling Cows Date: 13 Mar 1998 06:19:36 -0800 Organization: TTUHSC Lines: 16 Sender: daemon@net.bio.net Distribution: world Message-ID: <35094025.B135548B@ttuhsc.edu> References: <3507972c.7732046@news1.abac.com> Reply-To: phyan@ttuhsc.edu NNTP-Posting-Host: net.bio.net Dave: You have to find out what is the terminal velocity of a cow. How good are they at sky surfing. For instance a cat is most likely to survive any free-fall. I remember my little sister doing the experiment when she was 4 years old throwing my cat from different height and 20 feet or 50 feet did not make a difference. I'm sure a cat fly better than cow so I would assume that whether the cow fall from 300 feet or 30000 feet does not make a difference. Now you have to recalculate as explained by Jerome Villanova. If jerome was right cows would be considered a weapon of mass destuction. Alan Neely From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!agate!cgl!dek From: dek@socrates.ucsf.edu (David Konerding) Newsgroups: bionet.biophysics Subject: Re: Calc. Velocity of Falling Cows Date: 13 Mar 1998 17:50:29 GMT Organization: UCSF Computer Graphics Lab Lines: 17 Message-ID: References: <199803131524.JAA05679@xhost4> NNTP-Posting-Host: socrates.ucsf.edu X-Newsreader: slrn (0.9.1.1 BETA UNIX) In article <199803131524.JAA05679@xhost4>, zauhar@elara.tripos.com wrote: > The terminal velocity calculation is what's most interesting - > is Stoke's law a reasonable approximation for something as big > as a cow? I would think not.... > > Randy it also depends whether the cow is spherical (a common enough assumption) -- -------------------------------------------------------------------------------- Email: dek@cgl.ucsf.edu David Konerding WWW: http://picasso.ucsf.edu/~dek -------------------------------------------------------------------------------- Snail: Graduate Group in Biophysics Medical Sciences 926, Box 0446 University of California San Francisco, CA 94143 From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!ljlbio.com!jowicki From: jowicki@ljlbio.com (Jack Owicki) Newsgroups: bionet.biophysics Subject: FW: Calc. Velocity of Falling Cows Date: 13 Mar 1998 10:37:44 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 35 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Reminds me of the old joke about the physicist's model of a cow...a spherical body isotropically radiating milk. ...Jack ---------- From: dek@socrates.ucsf.edu [SMTP:dek@socrates.ucsf.edu] Sent: Friday, March 13, 1998 9:50 AM To: biophys@net.bio.net Subject: Re: Calc. Velocity of Falling Cows In article <199803131524.JAA05679@xhost4>, zauhar@elara.tripos.com wrote: > The terminal velocity calculation is what's most interesting - > is Stoke's law a reasonable approximation for something as big > as a cow? I would think not.... > > Randy it also depends whether the cow is spherical (a common enough assumption) -- ----------------------------------------------------------------------- --------- Email: dek@cgl.ucsf.edu David Konerding WWW: http://picasso.ucsf.edu/~dek ----------------------------------------------------------------------- --------- Snail: Graduate Group in Biophysics Medical Sciences 926, Box 0446 University of California San Francisco, CA 94143 From owner-biophysics@net.bio.net Thu Mar 12 22:00:00 1998 Path: biosci!elara.tripos.com!zauhar From: zauhar@elara.tripos.com Newsgroups: bionet.biophysics Subject: Re: FW: Calc. Velocity of Falling Cows Date: 13 Mar 1998 11:51:25 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 21 Sender: daemon@net.bio.net Distribution: world Message-ID: <199803131948.NAA11741@xhost4> NNTP-Posting-Host: net.bio.net I think the grant application idea is excellent - especially if some preliminary data can be worked up on the effects of bovine projectiles on hardened targets .... Randy All opinions expressed here are mine, not my employer's ///////////////////////////////////////////////////////////////////////// \\ Randy J. Zauhar, PhD | E-mail: zauhar@tripos.com // \\ Tripos, Inc. | : zauhar@fastrans.net // \\ 1699 S. Hanley Rd., Suite 303 | Phone: (314) 647-1099 Ext. 3382 // \\ St. Louis, MO 63144 | // ///////////////////////////////////////////////////////////////////////// ** ** ** "If you have conceptions of things that you can have no conception ** ** of, then the conception and the thing appear to co-incide." ** ** --- C.G. Jung ** ************************************************************************* From owner-biophysics@net.bio.net Sat Mar 14 22:00:00 1998 Path: biosci!agate!newsfeed.kornet.nm.kr!howland.erols.net!newshub.northeast.verio.net!newsserver.jvnc.net!newsreader.jvnc.net!not-for-mail From: editor Newsgroups: bionet.biophysics Subject: biotech directory Date: Sun, 15 Mar 1998 11:05:15 -0500 Organization: Verio Northeast Lines: 19 Message-ID: <350BFC3B.7DBC@megatype.com> NNTP-Posting-Host: prn-ts1-21.jvnc.net Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.02 (Win95; I) Princeton, NJ: The 15th Edition of Mega-Type's Genetic Engineering & Biotechnology Related Firms Worldwide Directory (ISBN 1-880866-16-2) offers detailed information over 4,000 firms. Listings include complete address information, phone, toll-free, fax and TELEX numbers, E-MAIL addresses/web sites and contact information for CEO/President, Project Manager, Research Director, Buyer and Public Relations. Also detailed technical highlights comments are included with the listings. A comprehensive search engine allows you to find listings based on a free text search of technical highlights or by name, industry code, city, state or country. Listings are provided FREE. You may email our office to receive a copy of your firm's listing. Since the directory is now on-line, updates may be entered throughout the year. As an added service to the industry, we are providing FREE areas to post your company's news or employment requirements. Space is limited and content is subject to review and editorial discretion. Check us out at www.megatype.com. From owner-biophysics@net.bio.net Sun Mar 15 22:00:00 1998 From: "marei" Newsgroups: bionet.biophysics Subject: What is new in ionic channels Date: Mon, 16 Mar 1998 22:44:45 +0100 Lines: 6 X-Newsreader: Microsoft Outlook Express 4.72.2106.4 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.2106.4 NNTP-Posting-Host: 195.2.1.50 Message-ID: <350dab27.0@info.xpoint.at> Path: biosci!agate!logbridge.uoregon.edu!news.maxwell.syr.edu!Cabal.CESspool!bofh.vszbr.cz!newscore.univie.ac.at!193.171.255.24.MISMATCH!newsfeed03.univie.ac.at!03-newsfeed.univie.ac.at!info.xpoint.at!195.2.1.50 I am very concern that is nothing is going on in the newsgroup. Is there is nothing important in biophysics. Or all the problems of the Ca channels are solved. From owner-biophysics@net.bio.net Mon Mar 16 22:00:00 1998 Path: biosci!agate!howland.erols.net!newspeer.monmouth.com!uvsq.fr!not-for-mail From: Jerome Villanova Newsgroups: bionet.biophysics Subject: falling cows passing sound speed Date: Tue, 17 Mar 1998 15:45:01 +0100 Organization: Universite de Versailles/St Quentin en Yvelines - France Lines: 14 Message-ID: <350E8C6D.D8DF7EC2@robot.uvsq.fr> NNTP-Posting-Host: pluton.robot.uvsq.fr Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.04 [en] (X11; I; SunOS 4.1.4 sun4m) What happened to the falling cows guy ? I'd like to have some feedback about what his teacher said and stuff. Oh, if you take the friction of the air into account, the maximum speed attined by the cow should be around 200 km/h. That would be a reasonnable 55.5 m/s. -- ------------------------------------ Jerome X Villanova E.mail: villa@robot.uvsq.fr ------------------------------------- From owner-biophysics@net.bio.net Mon Mar 16 22:00:00 1998 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.biophysics Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 17 Mar 1998 02:00:06 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 233 Sender: daemon@net.bio.net Distribution: world Message-ID: <199803171000.CAA13640@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-biophysics@net.bio.net Mon Mar 16 22:00:00 1998 Path: biosci!UCONNVM.UCONN.EDU!RHODES From: RHODES@UCONNVM.UCONN.EDU Newsgroups: bionet.biophysics Subject: Looking for Philo Date: 16 Mar 1998 18:45:18 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 12 Sender: daemon@net.bio.net Distribution: world Message-ID: <980316.214401.EST.RHODES@UConnVM.UConn.Edu> NNTP-Posting-Host: net.bio.net Does anyone have a contact for John Philo? Last I knew, he was at Amgen, but I tried there without success last week. Thanks!! |-----------------------------O==O----------------------------| | David G. Rhodes O==O Phone 860-486-5413 | | School of Pharmacy; U-92 O==O Fax 860-486-4998 | | University of Connecticut O==O | | Storrs, CT 06269-2092 O==O rhodes@uconnvm.uconn.edu | |_____________________________O==O____________________________| I love deadlines - especially the "whoosh" sound as they go flying by. From owner-biophysics@net.bio.net Mon Mar 16 22:00:00 1998 Path: biosci!NMR.UTMB.EDU!bruce From: bruce@NMR.UTMB.EDU (Bruce Luxon) Newsgroups: bionet.biophysics Subject: Structural Biology Symposium Date: 17 Mar 1998 10:06:24 -0800 Organization: Sealy Center for Structural Biology Lines: 151 Sender: daemon@net.bio.net Distribution: world Message-ID: <350EBC2E.2DB78625@nmr.utmb.edu> Reply-To: bruce@nmr.utmb.edu NNTP-Posting-Host: net.bio.net THE THIRD ANNUAL STRUCTURAL BIOLOGY SYMPOSIUM University of Texas Medical Branch at Galveston April 3-5, 1998 Dear Colleague: I would like to invite you and your colleagues to participate in The Third Annual Structural Biology Symposium organized by the Sealy Center for Structural Biology and the Department of Human Biological Chemistry and Genetics of the University of Texas Medical Branch at Galveston, Texas. The meeting will start on Friday afternoon at 4:00 p.m., April 3, 1998 and ends on Sunday at noon, April 5, 1998. Note that there is NO REGISTRATION FEE for this symposium. The speakers at the symposium are distinguished researchers in the field of Structural Biology. Dr. Wayne A. Hendrickson Columbia University, New York, NY "Structural Biology of the HIV Envelope Glycoprotein gp120" Dr. Wah Chiu Baylor College of Medicine, Houston "Scaffolding-Assisted Assembly Mechanism in Herpesvirus Capsid" Dr. Michael Rossmann Purdue University "Interaction of Rhinoviruses With Their Cellular Receptors" Dr. Juli Feigon University of California Los Angeles "New Views on Nucleic Acid Folding from Structures of Small RNA's" Dr. Michael Summers University of Maryland Baltimore County "NMR Studies of HIV-1 Gag Proteins and Gag-Genome Recognition" Dr. Michael Hecht University of Princeton "De Novo Proteins from Designed Combinatorial Libraries" Dr. Susan S. Taylor University of California San Diego "cAMP-Dependent Protein Kinase: Structural Basis for Function, Regulation and Subcellular Localization" Dr. Homme W. Hellinga Duke University Medical Center "Rational Design of Protein Function" Dr. D. Wayne Bolen University of Texas Medical Branch "Protein Folding in Organisms Adapted to Environmental Stresses: The Medium is the Message" Dr. John Kuriyan The Rockefeller University "The Regulation of Src-Family Tyrosine Kinases" Dr. Vincent J. Hilser University of Texas Medical Branch "Viewing Proteins as Ensembles" Specific information regarding registration, poster session and hotel reservations is available at http://www.scsb.utmb.edu/symposium/symp98.html. Please forward the information to other appropriate individuals in your department. On behalf of the co-chairs, Profs. James Lee and Robert Fox and the organizing committee I look forward to your participation. Bruce Luxon THE THIRD ANNUAL STRUCTURAL BIOLOGY SYMPOSIUM April 3-5, 1998 Sealy Center for Structural Biology Department of Human Biological Chemistry & Genetics University of Texas Medical Branch at Galveston REGISTRATION No registration fee. See registration form (WEB site) RECEPTION, LUNCH AND BANQUET Reception on Friday, April 3, is open to everyone. Participant of lunch and banquet, please send a check for $65. Participant of lunch, please send a check for $10. Payable to: UTMB-SCSB (subject to availability) POSTER SESSION Submit abstract by Friday, March 27, 1998. The abstract should fit on one page with one inch margin on all sides. A space of 4_ x 6_ has been allocated for each poster presentation. HOTEL RESERVATION A block of rooms has been reserved for attendees at the beachfront Hotel Galvez. Rate: $89 Single/Double $99 Triple $109 Quadruple (with availability) Call 1-800-392-4285 Registration form may be obtained from: Structural Biology Symposium Shirley Broz Department of Human Biological Chemistry & Genetics University of Texas Medical Branch at Galveston 5.138 Medical Research Building Galveston, TX 77555-1055 Phone: (409) 772-2281 FAX: (409) 772-4298 E-mail: sbroz@utmb.edu -- =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-= Bruce A. Luxon, Ph.D Associate Professor Sealy Center for Structural Biology Dept. of Human Biological Chemistry & Genetics University of Texas Medical Branch Galveston, TX 77555-1157 (409)747-6802; Fax (409)747-6850 http://www.hbcg.utmb.edu/ http://www.nmr.utmb.edu/ mailto:bruce@nmr.utmb.edu =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-= From owner-biophysics@net.bio.net Tue Mar 17 22:00:00 1998 From: "marei" Newsgroups: bionet.biophysics Subject: Test Date: Wed, 18 Mar 1998 02:57:37 +0100 Lines: 3 X-Newsreader: Microsoft Outlook Express 4.72.2106.4 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.2106.4 NNTP-Posting-Host: 195.2.3.31 Message-ID: <350f2a34.0@info.xpoint.at> Path: biosci!agate!usenet.INS.CWRU.Edu!news.ysu.edu!Cabal.CESspool!bofh.vszbr.cz!newscore.univie.ac.at!193.171.255.24.MISMATCH!newsfeed03.univie.ac.at!03-newsfeed.univie.ac.at!info.xpoint.at!195.2.3.31 From owner-biophysics@net.bio.net Tue Mar 17 22:00:00 1998 Path: biosci!agate!newsgate.duke.edu!nntprelay.mathworks.com!newsfeed.internetmci.com!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: prismx@scienceweek.com (Claire Haller) Newsgroups: bionet.neuroscience,bionet.biophysics,bionet.cellbiol,bionet.general,sci.misc Subject: SCIENCE-WEEK: Daily Science News Briefs Date: Wed, 18 Mar 1998 15:21:05 GMT Organization: SCIENCE-WEEK Lines: 12 Message-ID: <6eoori$1d8@suriname.earthlink.net> Reply-To: prismx@scienceweek.com NNTP-Posting-Host: 153.36.166.180 X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.neuroscience:21630 bionet.biophysics:4077 bionet.cellbiol:9060 bionet.general:29573 Daily science news briefs, many of which are to be explicated in forthcoming issues of SCIENCE-WEEK, are now available for access at URL: http://scienceweek.com/daily.htm This bulletin file is updated daily. The Editors SCIENCE-WEEK editors@scienceweek.com http://scienceweek.com From owner-biophysics@net.bio.net Tue Mar 17 22:00:00 1998 Path: biosci!agate!newsfeed.wli.net!news-peer-west.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!Sprint!news.maxwell.syr.edu!news.mel.connect.com.au!news.syd.connect.com.au!ns.dot.net.au!not-for-mail From: Geoff Heyes Newsgroups: bionet.biophysics Subject: animal experiments Date: Tue, 17 Mar 1998 10:54:05 -0800 Organization: Dot Communications Ltd, Australia, +612 9281-1111 Lines: 67 Message-ID: <350EC6CD.C0210DE3@f1.net.au> Reply-To: geoffhys@f1.net.au NNTP-Posting-Host: dialup-010.f1.net.au Mime-Version: 1.0 Content-Type: multipart/mixed; boundary="------------029ACCF5755EA21AA5FD8E6C" X-Mailer: Mozilla 4.04 [en] (Win95; I) This is a multi-part message in MIME format. --------------029ACCF5755EA21AA5FD8E6C Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit According to the ARDF (Alternatives Research and Development Foundation): "Since their inception 1902 2/3rds of the Nobel prizes in physiology and medicine went to projects that primarily or entirely used alternative techniques. 1995 Tufts University study found use of animals in laboratories in the Western world has declined nearly 50% in the last decade. "All significant advances related to such diseases as AIDS Alzheimer's disease and cancer have come form the use of alternatives. " Adoption of in vitro screening methods by the National Cancer Institute replaced millions of animals in their laboratories. To help achieve "Progress without pain" call 1-800-SAY-AAVS -- advert My Homepage: Human-Animal Ethics and the Vegetarian
 
  --------------029ACCF5755EA21AA5FD8E6C Content-Type: text/x-vcard; charset=us-ascii; name="vcard.vcf" Content-Transfer-Encoding: 7bit Content-Description: Card for Geoff Heyes Content-Disposition: attachment; filename="vcard.vcf" begin: vcard fn: Geoff Heyes n: Heyes;Geoff email;internet: geoffhys@f1.net.au x-mozilla-cpt: ;0 x-mozilla-html: FALSE version: 2.1 end: vcard --------------029ACCF5755EA21AA5FD8E6C-- From owner-biophysics@net.bio.net Wed Mar 18 22:00:00 1998 Path: biosci!agate!newsfeed.wli.net!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!news.new-york.net!newsfeed.metronet.de!RRZ.Uni-Koeln.DE!news.rz.uni-duesseldorf.de!usenet From: Sascha Burg Newsgroups: bionet.biophysics Subject: Fe-chelat Date: Thu, 19 Mar 1998 14:45:25 +0100 Organization: Heinrich Heine Universitaet Duesseldorf Lines: 12 Message-ID: <35112175.493D@uni-duesseldorf.de> Reply-To: burgs@uni-duesseldorf.de NNTP-Posting-Host: 134.99.200.202 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01Gold [de] (Win95; I) Hi, I'am searching for information about some fe-chelates. I need to know the redoxpotentials, stability-constants and other basic informations especially from fe-edta, fe-malat, fe-citric, fe-oxalat and fe malonic. If somebody knows where i can get these informations , i would be very happy about your response. Thanks in advance, Sascha P.S.: May be you can tell me a better news-group for my question. From owner-biophysics@net.bio.net Wed Mar 18 22:00:00 1998 Path: biosci!agate!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!news.mel.connect.com.au!harbinger.cc.monash.edu.au!lucy.cc.swin.edu.au!bud!070606 From: 070606@bud.swin.edu.au (Adriano Uliana) Newsgroups: bionet.biophysics Subject: Research into blood gas analysis techniques Date: 18 Mar 1998 23:54:04 GMT Organization: Swinburne University of Technology Lines: 7 Message-ID: <6epmqs$h1j$1@lucy.cc.swin.edu.au> NNTP-Posting-Host: 136.186.1.113 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Newsreader: TIN [version 1.2 PL2] I'm a 4th yr undergraduate at Swinburne Uni (Australia) studyinf Med. Biophysics. I'm currently researching the feasibility of an invasive blood gas analyser. I would greatly appreciate any information on blood gas analysis devices and biotechnology involoved (e.g web pages etc) Thanking you in advance Adriano Uliana <070606@bud.swin.edu.au> From owner-biophysics@net.bio.net Wed Mar 18 22:00:00 1998 Path: biosci!daresbury!uninett.no!newscore.univie.ac.at!news-raspail.gip.net!news-lond.gip.net!news.gsl.net!gip.net!peer.news.u-net.net!u-net!yama.mcc.ac.uk!not-for-mail From: rick@omni.cc.purdue.edu (Rick Millane) Newsgroups: sci.physics,sci.physics.research,sci.image.processing,sci.polymers,sci.research,sci.research.postdoc,sci.techniques.xtallography,sci.edu,bionet.biophysics,bionet.xtallography,bionet.jobs.offered,purdue.physics.general,purdue.math.general Subject: Post-doc position in polymer crystallography Followup-To: poster Date: 19 Mar 1998 22:56:05 GMT Organization: Purdue University Lines: 26 Approved: spr@multivac.jb.man.ac.uk (sci.physics.research) Message-ID: <6erglp$3e4@mozo.cc.purdue.edu> NNTP-Posting-Host: multivac.jb.man.ac.uk Keywords: crystallography, post-doc, computational, image reconstruction Xref: biosci bionet.biophysics:4082 bionet.xtallography:4121 bionet.jobs.offered:8400 [Moderator's note: I have set followups to the poster. -P.H.] POSTDOCTORAL POSITIONS COMPUTATIONAL X-RAY CRYSTALLOGRAPHY POLYMER CRYSTALLOGRAPHY Purdue University Postdoctoral positions are available at Purdue University on projects concerned with the development of new computational algorithms for macromolecular and polymer crystallography. Current interests are in the development of new electron density modification algorithms for protein crystallography, new reconstruction methods in fiber diffraction, and structural analysis of disordered polymer systems. Applicants should have a Ph.D. and experience in computational methods in x-ray crystallography, or in a related field. Experience with C programming, Unix and crystallography are highly desirable. Send cv, a summary of research experience and interests, and the names of three referees to Dr. Rick Millane, Whistler Center for Carbohydrate Research, and Computational Science and Engineering Program, Purdue University, West Lafayette, IN 47907-1160, tel. 765-494-9272, fax. 765-494-7953, rmillane@purdue.edu. Purdue University is an AA/EOE. From owner-biophysics@net.bio.net Wed Mar 18 22:00:00 1998 Path: biosci!agate!logbridge.uoregon.edu!europa.clark.net!208.134.241.18!newsfeed.internetmci.com!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: John Philo <"jphilo*NO SPAM12*"@earthlink.net> Newsgroups: bionet.biophysics Subject: Re: Looking for Philo Date: Thu, 19 Mar 1998 14:35:57 -0800 Organization: Alliance Protein Laboratories Lines: 7 Message-ID: <35119DCD.6344@earthlink.net> References: <980316.214401.EST.RHODES@UConnVM.UConn.Edu> Reply-To: jphilo*NO, SPAM12*@earthlink.net NNTP-Posting-Host: 207.217.142.17 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.03 (Win95; I) Here I am, Dave. You can't reach me at Amgen anymore because our whole biophysics group was laid of---I thought you knew. -- John Philo, Alliance Protein Laboratories *** Remove "*NO SPAM12*" from return address before replying. *** From owner-biophysics@net.bio.net Wed Mar 18 22:00:00 1998 Path: biosci!newshost.lanl.gov!ncar!news-out.internetmci.com!newsfeed.internetmci.com!4.1.16.34!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!rill.news.pipex.net!pipex!news-lond.gip.net!news.gsl.net!gip.net!peer.news.u-net.net!u-net!yama.mcc.ac.uk!not-for-mail From: rick@omni.cc.purdue.edu (Rick Millane) Newsgroups: sci.physics,sci.physics.research,sci.image.processing,sci.polymers,sci.research,sci.techniques.xtallography,sci.edu,bionet.biophysics,bionet.xtallography,bionet.jobs.offered,purdue.physics.general,purdue.math.general Subject: JOB: Graduate assistantships in computational crystallography and image reconstruction Followup-To: poster Date: 18 Mar 1998 22:30:13 GMT Organization: Purdue University Lines: 25 Approved: spr@multivac.jb.man.ac.uk (sci.physics.research) Message-ID: <6epdbf$c78@mozo.cc.purdue.edu> NNTP-Posting-Host: multivac.jb.man.ac.uk Keywords: crystallography, graduate assitantships, computational, image reconstruction X-Newsreader: NN version 6.5.0 (NOV) Xref: biosci bionet.biophysics:4080 bionet.xtallography:4120 bionet.jobs.offered:8399 [Moderator's note: I have set followups to the poster. -P.H.] GRADUATE ASSISTANTSHIPS AVAILABLE FOR STUDY TOWARDS THE PH.D. COMPUTATIONAL X-RAY CRYSTALLOGRAPHY POLYMER CRYSTALLOGRAPHY AND SIMULATION IMAGE RECONSTRUCTION Purdue University Graduate assistantships are available for study towards the Ph.D. degree in the Computational Science and Engineering Program at Purdue University. Research projects are available in theory and algorithm development for x-ray crystallography, analysis of polymer structures using x-ray diffraction, and image reconstruction algorithms. Applicants should have a M.S. (or possibly a B.S.) degree in a physical science, mathematics or engineering, and interest and abilities in theoretical/computational science. Interested individuals should contact Dr. R.P. Millane, Whistler Center for Carbohydrate Research, and Computational Science and Engineering Program, Purdue University, West Lafayette, IN 47907-1160, tel. 765-494-9272, fax. 765-494-7953, rmillane@purdue.edu. Purdue University is an AA/EO employer. From owner-biophysics@net.bio.net Fri Mar 20 22:00:00 1998 Path: biosci!agate!awabi.library.ucla.edu!208.134.241.18!newsfeed.internetmci.com!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: prismx@scienceweek.com (Claire Haller) Newsgroups: bionet.neuroscience,bionet.biophysics,bionet.cellbiol,bionet.general,sci.misc Subject: SCIENCE-WEEK: Headlines March 20, 1998 Date: Sat, 21 Mar 1998 01:42:27 GMT Organization: SCIENCE-WEEK Lines: 67 Message-ID: <6ev5us$jki@argentina.earthlink.net> Reply-To: prismx@scienceweek.com NNTP-Posting-Host: 153.35.114.151 X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.neuroscience:21680 bionet.biophysics:4083 bionet.cellbiol:9078 bionet.general:29588 SCIENCE-WEEK is a free weekly Email digest of the news of science read each week by 50,000+ people in the scientific community in more than 40 countries. News briefs from the major journals are amplified with enough background material to make them intelligible to nonspecialists: the biology is detailed for physicists and chemists, and the physics and chemistry are detailed for biologists. Each issue contains 15 to 20 news reports, annotated listings of new books in the sciences, a Positions Available section, and other notices of interest to science professionals. The SW complete weekly news reports are available free via Email. To subscribe, send SUB SW to . The weekly edition of SW is also available free at URL: . The Email edition is an ASCII transmission of the weekly web posting, and is suitable for both plain text file readers (and Email software) and web browsers. A daily science news edition of SCIENCE-WEEK is available free at URL: . Many, but not all, reports in the daily edition appear in forthcoming weekly editions. The daily edition is not available via Email. Contents of the current weekly edition of SCIENCE-WEEK (March 20, 1998) ------------------------------------------------------ 1. On Intellectual Property and the American University 2. Xenotransplantation: A Group of Letters 3. Near-Closure of a University Chemist Plagiarism Case 4. Women Now Substantial Portion of All New US Chemists 5. A Global Approximation Technique for Multivariate Systems 6. On Black Holes as Real Astronomical Objects 7. On the Geological Evolution of Venus 8. On Quantum Theory Without Observers 9. Subsurface Charge Accumulation in a Quantum Hall Liquid 10. A New Technique for Size Separation of Macromolecules 11. Hydrogen Hypothesis for the First Eukaryote 12. Polyketide Synthases as Modular Enzymes 13. A Model for the Mechanism of a Human Topoisomerase 14. Host Derived Amino Acids Support Symbiotic Bacteria 15. Identification of a Cell Membrane Nucleic Acid Channel 16. Plant Performance and Induced Responses to Herbivory 17. Single Neuron Control of Synaptic Efficacy 18. Characterization of an In Vitro Blood-Brain Barrier 19. Muscle Regeneration by Bone-Marrow-Derived Cells 20. Genetic Traces of Ancient Demography Book Notes Notices - Positions Available Notices - Miscellaneous SCIENCE-WEEK is a free retransmission educational resource, which means this headline notice and each weekly issue of SCIENCE-WEEK itself can be retransmitted if intact by any installation. All back issues of SCIENCE-WEEK are available at the URL below. The Editors SCIENCE-WEEK A Free Weekly Digest of the News of Science editors@scienceweek.com http://scienceweek.com From owner-biophysics@net.bio.net Fri Mar 20 22:00:00 1998 Path: biosci!agate!newsfeed.wli.net!portc04.blue.aol.com!audrey02.news.aol.com!not-for-mail From: janczek@aol.com (JanCzek) Newsgroups: bionet.biophysics Subject: Method of measuring cell culture respiration Date: 21 Mar 1998 05:16:29 GMT Lines: 23 Message-ID: <1998032105162900.AAA21979@ladder01.news.aol.com> NNTP-Posting-Host: ladder01.news.aol.com X-Admin: news@aol.com Organization: AOL http://www.aol.com Measuring cell culture respiration We have developed a method of measuring cell culture respiration by measuring gas exchanges in the head space of the 50 ml chamber. 10 mg of the adipocytes isolated from the epidydemal fat pads of a rat were incubate at 37 degree C. Both O2 consumption and CO2 production were measure by sampling gas from the chamber’s head space and returning it back to the chamber after passing through very sensitive O2 and CO2 analyzers. Measurements were conducted over 21 hours and accumulated oxygen consumption from this sample over 21 h was 275 microliters of O2 equivalent to rate of consumption equal to 13.1 ul O2/h per 10 mg. Samples were slightly shaken to provide for equilibrium between gaseous state and dissolved state of gases. As in the past similar measurements required dissolved oxygen probes measuring O2 consumption and CO2 production by sampling gas from the head space may have many advantages. If you are interested in more details of this method and instruments used please contact: Jan Czekajewski,Ph.D. and Pradip Ghosh, Ph.D. E-mail:janczek@aol.com From owner-biophysics@net.bio.net Mon Mar 23 22:00:00 1998 Path: biosci!agate!news-spur1.maxwell.syr.edu!news.maxwell.syr.edu!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!portc02.blue.aol.com!pitt.edu!bb3.andrew.cmu.edu!honeysuckle.srv.cs.cmu.edu!das-news2.harvard.edu!oitnews.harvard.edu!hpngsv01.mgh.harvard.edu!misha.mgh.harvard.edu!user From: mmisha@nmr.mgh.harvard.edu (M. Papisov) Newsgroups: bionet.biophysics Subject: Re: Fe-chelat Date: Tue, 24 Mar 1998 16:50:39 -0500 Organization: MGH & HMS Lines: 28 Message-ID: References: <35112175.493D@uni-duesseldorf.de> NNTP-Posting-Host: misha.mgh.harvard.edu Library is your only way. Find a good book, or a review, on iron complexes. Try, for example, this one: Chemistry of Iron, J. Silver (Ed.), Blackie Academic & Professional, 1993, ISBN: 0751400629 In article <35112175.493D@uni-duesseldorf.de>, burgs@uni-duesseldorf.de wrote: > I'am searching for information about some fe-chelates. I need to know > the redoxpotentials, stability-constants and other basic informations > especially from fe-edta, fe-malat, fe-citric, fe-oxalat and fe malonic. > If somebody knows where i can get these informations , i would be very > happy about your response. > > Thanks in advance, > > Sascha > > P.S.: May be you can tell me a better news-group for my question. ______________He who rides on a tiger never dismounts________________ Please delete the very first letter in my email address to reply. Nobody at all, including my past, current and future employers, is responsible for whatever is written above. From owner-biophysics@net.bio.net Tue Mar 24 22:00:00 1998 Path: biosci!MAILER.UNI-MARBURG.DE!ullrichm From: ullrichm@MAILER.UNI-MARBURG.DE ("Matthias S. Ullrich") Newsgroups: bionet.biophysics Subject: PhD position in Marburg / Germany Date: 25 Mar 1998 01:55:14 -0800 Organization: Max Planck Institut for terrestrial Microbiology Lines: 37 Sender: daemon@net.bio.net Distribution: world Message-ID: <349434D5.7439@mailer.uni-marburg.de> Reply-To: ullrichm@mailer.uni-marburg.de NNTP-Posting-Host: net.bio.net ____________________________________________ GRADUATE RESEARCH ASSISTANT FELLOWSHIP AVAILABLE ____________________________________________ A graduate research assistant fellowship from the Deutsche Forschungsgemeinschaft (DFG) is currently available to study the molecular mechanisms of temperature signalling in plant-bacteria interactions. We are seeking a highly motivated individual who wants to work on protein-membrane interactions at the molecular level. A membrane associated histidine protein kinase, CorS, will be studied using in vitro lipid bilayer techniques (for more detailed information see http://www.uni-marburg.de/mpi/ullrich/ullrich.htlm). The position will be funded for a total of three years giving the successful candidate the chance to acquire the PhD degree. The candidate should have an MS degree in biology, biochemistry, chemistry, molecular biology, or a related biomedical research field with excellent university certificates and should not be older than 27 years. The Max Planck Institute for terrestrial Microbiology is a well-funded research facility located in Marburg, Germany. Please forward your letter of application, CV, transcripts, and one letter of recommendation to: Dr. Matthias Ullrich Max-Planck-Institut f=FCr terrestrische Mikrobiologie Karl-von-Frisch-Strasse 35043 Marburg / Lahn Germany Fax: (+49) 6421 178 609 Phone: (+49) 6421 178 600 E-mail: ullrichm@mailer.uni-marburg.de Deadline for receipt of applications is January 1, 1998 From owner-biophysics@net.bio.net Tue Mar 24 22:00:00 1998 Path: biosci!agate!nntp-out.monmouth.com!newspeer.monmouth.com!howland.erols.net!newsfeed.gte.net!newsfeed.ecrc.net!newsfeed.nacamar.de!news-hh.maz.net!cls.net!not-for-mail From: Malte Boisly Newsgroups: bionet.biophysics Subject: Facharbeit über das menschliche Ohr Date: Wed, 25 Mar 1998 23:43:23 +0100 Organization: CLS Internet Services GmbH Lines: 14 Message-ID: <3519888B.1A36@kiel.netsurf.de> NNTP-Posting-Host: pppm14.kiel.netsurf.de Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Mailer: Mozilla 3.01 (Win95; I) Hi Leute! Hat irgend jemand Informationen über das menschliche Ohr?? So zum Beispiel als Anhaltspunkte: - wie funktioniert das Ohr? - wieso hat das Ohr solch eine merkwürdige äußere Form? Ich suche eigentlich alles über das Ohr, nur nicht was man gegen Ohrensausen machen kann. davon hab ich schon genaug aus dem WWW. Falls jemand etwas hat, und mir bei meiner Facharbeit behilflich sein möchte, so möge er die Infos (z.B.: Texte, WWW-Adressen, etc) an folgende e-Mail Adresse schicken: Malte.Boisly@kiel.netsurf.de Vielen Dank schon mal im Voraus. From owner-biophysics@net.bio.net Wed Mar 25 22:00:00 1998 Path: biosci!NWU.EDU!mhosey From: mhosey@NWU.EDU (Marlene Hosey) Newsgroups: bionet.biophysics Subject: Post-doctoral positions Date: 26 Mar 1998 14:31:36 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 70 Sender: daemon@net.bio.net Distribution: world Message-ID: <3.0.3.32.19980326161601.006ab3d0@casbah.acns.nwu.edu> NNTP-Posting-Host: net.bio.net Dear Colleagues: I am currently searching for a few good people to fill positions recently vacated by a group of very productive students who recently completed their PhDs in the lab. If you know of students who are currently finishing their PhD, or of others who might be looking for postdoctoral positions, or might be relocating to the Chicago area, I would appreciate it if you would bring their attention to the notice below. Thanks for your help! Marlene ---------------------------------------------------------------------------- -------- POSTDOCTORAL POSITIONS AVAILABLE to study regulation of receptors and channels by protein phosphorylation Studies focus on two topics. One concerns the molecular events underlying desensitization of G-protein coupled receptors, and uses the family of muscarinic cholinergic receptors as a model of neurotransmitter receptors known to play important roles in the central and peripheral nervous system. The second project concerns the regulation of voltage-dependent calcium channels by receptor mediated signaling pathways. The available positions are for studies on either project. A recent PhD with experience in molecular and cellular biology, biochemistry and/or electrophysiology is preferred, but attention will be given to all highly qualified individuals with excellent credentials and publications. Further information can be gained at our home page: http://scooter.pharm.nwu.edu/index.htm. Interested individuals should send a CV and names of three referees to mhosey@nwu.edu. Recent publications: Lee, K. B., Pals-Rylaarsdam, R., Benovic, J. L. and Hosey, M. M. (1998) Arrestin-independent internalization of the m1, m3 and m4 subtypes of muscarinic cholinergic receptors. J. Biol. Chem., in press. Gurevich, V.V., Pals-Rylaarsdam, R., Benovic, J. L., Hosey, M. M. and Onorato, J. J. (1997) Agonist- receptor-arrestin: an alternative ternary complex with high agonist affinity. J. Biol. Chem. 272, 28849-28852. Pals-Rylaarsdam, R., Gurevich, V. V., Lee, K. B., Ptasienski, J. A., Benovic, J. L. and Hosey, M. M. (1997) Internalization of the m2 muscarinic acetylcholine receptor: Arrestin-independent and -dependent pathways. J. Biol. Chem. 272, 23682-23689. Gao, T., Yatani, A., Dell'Acqua, M. L., Sako, H., Green, S. A., Dascal, N., Scott, J. D., and Hosey, M. M. (1997) Cyclic AMP-dependent regulation of cardiac L-type calcium channels requires membrane targeting of protein kinase A and phosphorylation of channel subunits. Neuron, 19,185-196. Gao, T., Puri., T. S., Gerhardstein, B. L., Chien, A. J., Green, R. D. and Hosey, M. M. (1997) Identification and subcellular localization of the subunits of L-type Ca channels and adenylyl cyclase in cardiac myocytes. J. Biol. Chem., 272, 19401-19407. Puri, T. S., Gerhardstein, B. L., Zhao, X.-L., Ladner, M. B., and Hosey, M. M. (1997) Differential effects of subunit interactions on protein kinase A and C mediated phosphorylation of L-type Ca channels. Biochemistry, 36, 9605-9615. Pals-Rylaarsdam, R. and Hosey, M. M. (1997) Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic cholinergic receptor. J. Biol. Chem. 272, 14152-14158. Perez-Leiros, C., Sterin-Borda, L., Borda, E. S., Goin, J. C. and Hosey, M. M. (1997) Desensitization and sequestration of human m2 muscarinic acetylcholine receptors by autoantibodies from patients with Chagas' disease. J. Biol. Chem. 272, 12989-12993. Chien, A. J., Carr, K. M., Shirokov, R. E., Rios, E., and Hosey, M. M. (1996) Identification of palmitoylation sites within the L-type Ca channel 2A subunit and effects on channel function. J. Biol. Chem. 271, 26465-26468. Hosey, M. M., Chien, A. J. and Puri, T. S. (1996) Structure and regulation of L-type calcium channels: a current assessment of the properties and roles of channel subunits. Trends Cardiovasc. Med., 6:265- 273. DebBurman, S. K., Ptasienski, J., Benovic, J. L. and Hosey, M. M. (1996) G-protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein subunits. J. Biol. Chem. 271, 22552-22562. From owner-biophysics@net.bio.net Thu Mar 26 22:00:00 1998 Path: biosci!agate!howland.erols.net!news-peer.sprintlink.net!news-backup-west.sprintlink.net!news-in-west.sprintlink.net!news.sprintlink.net!Sprint!207.217.77.43!newsfeed1.earthlink.net!nntp.earthlink.net!usenet From: prismx@scienceweek.com (Claire Haller) Newsgroups: bionet.neuroscience,bionet.biophysics,bionet.cellbiol,bionet.general,sci.misc Subject: SCIENCE-WEEK: Headlines March 27, 1998 Date: Fri, 27 Mar 1998 03:23:19 GMT Organization: SCIENCE-WEEK Lines: 69 Message-ID: <6ff641$d5p@chile.earthlink.net> Reply-To: prismx@scienceweek.com NNTP-Posting-Host: 153.35.114.132 X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.neuroscience:21773 bionet.biophysics:4094 bionet.cellbiol:9125 bionet.general:29628 SCIENCE-WEEK is a free weekly Email digest of the news of science read each week by 50,000+ people in the scientific community in more than 40 countries. News briefs from the major journals are amplified with enough background material to make them intelligible to nonspecialists: the biology is detailed for physicists and chemists, and the physics and chemistry are detailed for biologists. Each issue contains 15 to 20 news reports, annotated listings of new books in the sciences, a Positions Available section, and other notices of interest to science professionals. The SW complete weekly news reports are available free via Email. To subscribe, send SUB SW to . The weekly edition of SW is also available free at URL: . The Email edition is an ASCII transmission of the weekly web posting, and is suitable for both plain text file readers (and Email software) and web browsers. A daily science news edition of SCIENCE-WEEK is available free at URL: . The daily edition has a broader coverage of science news than the weekly edition, and the reports are usually much shorter. Many, but not all, reports in the daily edition appear in forthcoming weekly editions with added explications and background material. The free daily edition is not available via Email. Contents of the current weekly edition of SCIENCE-WEEK (March 27, 1998) ------------------------------------------------------ 1. AN ESSAY ON SCIENTIFIC ILLITERACY 2. A MEETING TO DISCUSS GERMLINE GENETIC ENGINEERING 3. A COMPROMISE TO PROTECT RADIO-ASTRONOMY OBSERVATIONS 4. ON COSMIC ANTIMATTER 5. DISCOVERY OF MOST DISTANT GALAXY WITH REDSHIFT AT 5.34 6. AN ANALYSIS OF OPTIMAL MODULATION OF A BROWNIAN RATCHET 7. FESHBACH RESONANCES IN A BOSE-EINSTEIN CONDENSATE 8. PROTEIN HYDRATION IN SOLUTION: X-RAY AND NEUTRON SCATTERING 9. A SELF-REPLICATING NUCLEOSIDE SURFACTANT VESICLE SYSTEM 10. NEW FUSION PROTEIN ENABLES VISUALIZATION OF DNA IN LIVE CELLS 11. CLEAVING DNA WITH DNA 12. ACTION OF PEPTIDE NUCLEIC ACIDS TARGETED TO RIBOSOMAL RNA 13. HUMAN IMMUNE SYSTEM LINKAGE TO A PLANT DEFENSE SYSTEM 14. CALCIUM SENSING OF METABOTROPIC GLUTAMATE RECEPTORS 15. A MUSCLE CELL TROPHIC FACTOR THAT INCREASES INNERVATION 16. EVIDENCE FOR HUMAN WATERCRAFT 800,000 YEARS AGO 17. INVOLVEMENT OF E-CADHERIN IN ADENOMA TO CARCINOMA TRANSITION 18. NOTED EPIDEMIOLOGIST W.M. HAENSZEL DEAD AT 87 Book Notes Product and Service Notes Notices - Positions Available Notices - Miscellaneous SCIENCE-WEEK is a free retransmission educational resource, which means this headline notice and each weekly issue of SCIENCE-WEEK itself can be retransmitted if intact by any installation. All back issues of SCIENCE-WEEK are available at the URL below. The Editors SCIENCE-WEEK A Free Weekly Digest of the News of Science editors@scienceweek.com http://scienceweek.com From owner-biophysics@net.bio.net Fri Mar 27 22:00:00 1998 Path: biosci!news.Stanford.EDU!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!ais.net!uunet!in4.uu.net!venus.hkstar.com!hkstar2!news@hkstar.com From: unix Newsgroups: bionet.biophysics Subject: 17-BETA-HYDROXYSTEROID-OXIDOREDUCTASE Date: Sat, 28 Mar 1998 15:03:51 -0800 Organization: Hong Kong Star Internet Ltd. Lines: 8 Message-ID: <351D81D7.474E@hotmail.com> NNTP-Posting-Host: ip-51-19.dialup.hkstar.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.02 (Win95; I; 16bit) Does any one know of any existing vitamins , minerals etc... that can inhibit 17-BETA-HYDROXYSTEROID-OXIDOREDUCTASE 's ability to turn androstenedione into testosterone ? Zinc and vitamin b 6 are known to have inhibitory effect on testosterone's conversion to dihytestosterone by preventing 5 alpha reductase from doing its job. Thanks From owner-biophysics@net.bio.net Sat Mar 28 22:00:00 1998 Path: biosci!CHEM.UFL.EDU!tan From: tan@CHEM.UFL.EDU (Weihong Tan) Newsgroups: bionet.biophysics Subject: Postdoctoral positions at University of Florid Date: 29 Mar 1998 09:59:33 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 56 Sender: daemon@net.bio.net Distribution: world Message-ID: References: NNTP-Posting-Host: net.bio.net Applications are invited for postdoctoral positions at the Department of Chemistry and the UF Brain Institute, University of Florida. The successful applicant should have a strong background in ANY ONE of the following areas: optical microscopy and spectroscopy, scanning probe microscopy, bioanalytical chemistry, biophysics or neuroscience. We are carrying out exciting research work in the following areas: 1) Novel optical microscopy for biomedical imaging and sensing; 2) Single biomolecule detection and manipulation; 3) Biochemical sensors and in-vivo monitoring; 4) Novel application of patch clamp technique and its development; 5) Functionalized nanostructures and arrayed nanodevices; 6) Molecular and subcellular mechanisms of ischemic stroke. These research activities are funded by the US National Science Foundation, the Office of Naval Research, Department of Defense and The Arnold Beckman Foundation. These positions are expected to be as long as three years. The successful applicant will be expected to show both individual initiative and ability to work as a team member. Our group has labs both in the Chemistry Department and in the newly established UF Brain Institute in the Medical School. This Institute is a national center for neuroscience and brain research. We thus have close interaction with biological and biomedical scientists. At University of Florida we have excellent working and living environment. Interested applicants should make an initial contact with Prof. Tan through e-mail, or send a CV with three reference letters to the following address: Prof. Weihong Tan Department of Chemistry and The UF Brain Institute University of Florida P.O. Box 117200 Gainesville, FL 32611-7200 USA Email: tan@chem.ufl.edu http://www.chem.ufl.edu/Groups/Tan/ Tel: 352-846-2410 Fax: 352-392-4651 ************************************************************** Weihong Tan Department of Chemistry and UF Brain Institute University of Florida 352-846-2410 (office) Gainesville, FL 32611-7200 352-392-4651 (Fax) http://www.chem.ufl.edu/Groups/Tan/ 352-392-1679 (lab) *************************************************************** From owner-biophysics@net.bio.net Tue Mar 31 23:00:00 1998 Path: biosci!genetics.com!derbe From: derbe@genetics.com (David Erbe) Newsgroups: bionet.biophysics Subject: Protein Engineering Position Available Date: 31 Mar 1998 19:40:26 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 23 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Protein Engineering Position Available Genetics Institute, Inc. Cambridge, MA A motivated Protein Engineer is wanted to join a multidisciplinary group to perform research directed at the discovery of small molecule inhibitors of various immune system targets. This group is housed in a facility equipped with the latest technology for structure based drug discovery including 600MHz NMR, X-ray lab, Computational Chemistry, and Medicinal Chemistry, all supported by dedicated Molecular Biology and Protein Biochemistry groups. Candidates should have interests and experience that include study of recombinant proteins, especially protein structure/function and engineering. Staff Scientist: Requires a Ph.D. In Molecular Biology, Biochemistry, Biophysics or equivalent and 0 - 5 years postdoctoral research. Contact via email: Dave Erbe (derbe@genetics.com)