From owner-biophysics@net.bio.net Mon Jan 25 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "Kathy King" 01/26 4:55 PM >>> Newsgroups: bionet.prof-society.biophysics Subject: Ligand Recognition and Molecular Gating Date: 26 Jan 1999 14:15:34 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 97 Sender: daemon@net.bio.net Approved: kking@biophysics.faseb.org Distribution: world Message-ID: <78leq6$h14@net.bio.net> NNTP-Posting-Host: net.bio.net Gordon Research Conference on: Ligand Recognition and Molecular Gating http://www.grc.uri.edu/programs/1999/ligand.htm Ventura, CA March 7-12, 1999 Chair: Thue W. Schwartz Vice chair: Diane M. Papazian Session 1: (Sunday p.m.) Topic: New 3D Structures of Membrane Proteins * Doug Rees: X-ray structure of a pentameric mechanosensitive channel from M. tuberculosis. * Speaker to be announced: Another braking and exciting 3D news story * Y.Fujiyoshi: Aquaporin and other membrane proteins studied by helium temp EM ________________________________________________________________ Session 2: (Monday a.m.) Topic: Multiple Molecular Mechanisms of Gating (Wayne Hubbell) * Eduardo Perozo: Structural rearrangements in proton-dependent K+ channel gating. * Pancho Bezanilla: Molecular mechanism of voltage gating in K+ channels. * Horst Vogel: Probing single ligand-gated ion channel molecules by combined electrical and optical measurements. * Peter Agre: Molecular mechanism of gating in aquaporins * David Julius: Capsaisin receptor and heat activated channels. ___________________________ Session 3: (Monday p.m.) Topic: Translocation and Solubilization of Proteins - in and out of Membranes * Alan Finkelstein: Protein translocation associated with voltage gating of toxin channels. * Harry Haigler: Soluble annexin forms transmembrane channel by reversible "inside-out" refolding. * Jean-Luc Popot: Amphipols: how to handle integral membrane proteins in detergent-free aqueous solutions'. ____________________________________________________ Session 4: (Tuesday a.m.) Topic: Protein-Protein Interactions in the Membrane (Don Engelman) * Don Engelman: Helix interactions in vivo - better physical chemistry through genetics. * John Spudich: A 7-helix phototaxis receptor - conformational changes couple signaling to a co-receptor. * Fiona Marshall: Surface expression of 7TM receptors through 1TM-7TM and 7TM-7TM heterodimerization. * Mark Lemon: Ligand-induced homo- and hetero-dimerization of growth factor receptor tyrosine kinases. ___________________________ Session 5: (Tuesday p.m.) Topic: Forces and Principles in Ligand Recognition (Barry Honig) * Barry Honig: Principles and forces of ligand recognition * Jim A.Wells: Molecular recognition at protein interfaces * Christian Elling: Metal-ion mediated ligand binding - 7TM receptor activation. __________________________________________________________________ Session 6: (Wedensday a.m.) Topic: $-barrel Membrane Proteins (Tilman Schirmer) * Tilman Schirmer: Selective versus non-selective porins * Jeremy Lakey: Ligand induced gating of OmpF porin beta-barrel ion channels * Susan Buchanan: The ferric enterobactin receptor - a beta-barrel active transporter * Kaspar Locher: Structure of the hydroximate receptor FhuA in its apo and holo form. ___________________________ Session 7: (Wedensday p.m.) Topic: Transporters - Recognition and Gating (Ron Kaback) * Michael P. Kavanaugh: Glutamate transport - as viewed form both the ligand and the transporter. * Ron Kaback: What to do while waiting for your protein to crystalize! * Shimon Schuldiner: Structure & function of the multidrug resistence pump EmrE _______________________________________________________________ Session 8: (Thursday a.m.) Topic: Conformational Changes & ligand binding in 7TM receptor (Gebhard Schertler) * Gebhard Schertler: Structure of bovine rhodopsin obtained by cryo-microscopy: a first view of an inverse agonist bound to a G-protein couple receptor * Wayne Hubbell: Rhodopsin - conformational changes of activation probed by EPR * Jean-Luc Galzi: Simultaneous time-resolved recording of signaling and ligand-binding by FRET in 7TM's * Falk Fahrenholtz: Cholesterol / steroid dependency of certain 7TMs * Bruce Conklin: Controlled in vivo ligand recognition of 7TM's in transgenic mice __________________________________________________________________ Session 9: (Thursday p.m.) Topic: De novo Design and Recognition in Membrane Proteins (Bill DeGrado) * Bill Degrado: De Novo design of membrane proteins * Hagan Bayley: Redesign of alpha-hemolysin - ligand recognition / bioprobe * Gerd Koechendorfer: Organic Synthetic approach to membrane proteins From owner-biophysics@net.bio.net Wed Jan 27 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Kathy King 01/28 5:26 PM >>> Newsgroups: bionet.prof-society.biophysics Subject: Extension of Mentorin Luncheon Deadline Date: 28 Jan 1999 14:48:42 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 48 Sender: daemon@net.bio.net Approved: kking@biophysics.faseb.org Distribution: world Message-ID: <78qpga$1o7@net.bio.net> NNTP-Posting-Host: net.bio.net Mentoring Luncheon (Registration must be received by February 15, 1999) The Committee for Professional Opportunities for Women (CPOW) and the Education Committee of the Biophysical Society are sponsoring a Mentoring Luncheon this year during the annual meeting. The luncheon will take place on Wednesday, February 17, 1999, at 12:00 Noon in the Baltimore Convention Center. The purpose of this luncheon is to provide society members the opportunity to talk informally about career development. We hope that the luncheon will provide young people an opportunity to develop informal mentoring relationships, junior faculty the opportunity to seek career advice "off-site" and personal and scientific exchanges for everyone. This informal format has become quite popular in other societies and we hope you will join us and encourage others to join. Participation will be by preregistration only. You may register for a box lunch or bring your own but do plan to participate. Topics to be discussed during this lunch are listed below. Each will take place in informal, roundtable discussion format moderated by a topic leader. Table assignments will be posted outside the luncheon room. Cost for the session is $10.00 if you are ordering lunch. Topics and lunch orders must be received in the Biophysical Society National Office by February 11 or submitted on-site in Room 311 of the Baltimore Convention Center by February 15 (February 16 for those not ordering lunch). Please visit http://www.biophysics.org/biophys/society/annmtg/mentoring.htm to register. TOPICS: A) What really counts in the tenure decision? Or, what you need to know before you're sitting at the table. B) How do you become an effective teacher? Or, how do you improve your teaching ratings? C) How do you move from academia to industry? D) The great balancing act: research, teaching, and community service. How does the family fit in? E) How to negotiate successfully in the work environment. Biophysical Society 9650 Rockville Pike, Bethesda, MD 20814-3998 Tel: 301-530-7114; Fax: 301-530-7133 E-mail: society@biophysics.faseb.org From owner-biophysics@net.bio.net Sun Jan 31 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "Kathy King" 02/01 2:53 PM >>> Newsgroups: bionet.prof-society.biophysics Subject: 1999 Young Investigator Awards Announced Date: 1 Feb 1999 12:13:22 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 40 Sender: daemon@net.bio.net Approved: kking@biophysics.faseb.org Distribution: world Message-ID: <7951t2$7s@net.bio.net> NNTP-Posting-Host: net.bio.net The Bioenergetics Subgroup is pleased to annouce the 1999 Young Investigator Awardees In addition to receiving their award, the honorees will have the opportunity to present their research during the upcoming Annual Meeting. The three recipients of the Young Investigator Award for 1999 are: 1) Ms. Alicia J. Kowaltowski from the Department of Pathologia Clinica, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, SP, 13083-970, Brazil Abstract title: BCL-2 PREVENTS MITOCHONDRIAL PERMEABILITY TRANSITION IN GT1-7 HYPOTHALAMIC TUMOR CELLS DUE TO INCREASED REDUCING POWER. A. J. Kowaltowski, A. E. Vercesi, and G. Fiskum. Department of Anesthesiology, The University of Maryland Baltimore, Baltimore, MD and Department of Pathologia Clinica, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil 2) Ms. Hau Tain from the Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma, USA. Abstract title: EVIDENCES FOR THE DOMAIN MOVEMENT OF THE IRON-SULFUR PROTEIN DURING THE CATALYTIC CYCLES OF CYTOCHROME bc1 COMPLEX. H. Tian, L. Yu, C.A. Yu; Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK. 3) Dr. Roger F. Castihlo from the Wallenberg Neuroscience Center, Lund University, Lund, Sweden Abstract title: OXIDATIVE STRESS, MITOCHONDRIAL FUNCTION AND ACUTE GLUTAMATE EXCITOTOXICITY IN CULTURED CEREBELLAR GRANULE CELLS. R.F. Castihlo, M.W. Ward, and David G. Nicholls; Neuroscience Institute, Department of Pharmacology and Neuroscience, University of Dundee, Dundee, Scotland, UK. From owner-biophysics@net.bio.net Sun Jan 31 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Kathy King" 02/01 2:51 PM >>> Newsgroups: bionet.prof-society.biophysics Subject: Annual Bioenergetics Subgroup Dinner Date: 1 Feb 1999 12:11:53 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 33 Sender: daemon@net.bio.net Approved: kking@biophysics.faseb.org Distribution: world Message-ID: <7951q9$4r@net.bio.net> NNTP-Posting-Host: net.bio.net The Annual Bioenergetics Dinner, Saturday, February 13, 1999, will take place at "Velleggia's" at Baltimore's Little Italy (829 East Pratt Street, Baltimore, MD 21202). This year, there will be a special after-dinner speaker. Dr. Janna P. Wehrle, Program Director, Cell Biology and Biophysics, NIGMS/NIH, "From E. coli to Cray: Are We Ready to Re-integrate Biological Chemistry?" will be the topic of her talk. Cocktails will be served at 7:00 pm and dinner at 7:30 pm with a cash bar. All subgroup members, bioenergeticists-at-large, and symposia speakers are invited. The dinner at Velleggia's will be a buffet in a private room with podium, etc. We will start with imported cheeses and antipasto. Prior to the buffet, a house salad will be served. The pasta courses are cannelloni and pasta with broccoli. The entrees are veal saltimbocca and shrimp & scallops. The vegetable is spinach a la velleggia. The desert collection consists of tortufo, cannoli, and tiramisu. Coffee, tea, and soft drinks are included. The price per person is $32.00 INCLUSIVE of taxes and gratuities. Dinner reservations should be placed in advance and are available on a first-come basis. Please make reservations with: Dr. Carmen Mannella Wadsworth Center Empire State Plaza, Box 509 Albany NY 12201-0509 carmen@wadsworth.org