From owner-cardiors@hgmp.mrc.ac.uk Mon Jul 3 23:19:54 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 84B1517B12; Mon, 3 Jul 2000 23:19:54 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 644D917B11; Mon, 3 Jul 2000 23:19:53 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id A0F3F415DC for ; Mon, 3 Jul 2000 23:19:52 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id XAA21396 for cardiors-list@hgmp.mrc.ac.uk; Mon, 3 Jul 2000 23:19:52 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: smisba@west.net (Herman Barrantes) X-Newsgroups: alt.russia,alt.sci,alt.taiwan,be.science,bionet.biology.cardiovascular Subject: SMI/CLINICA Message-ID: Organization: SMI Lines: 23 Date: Mon, 03 Jul 2000 15:14:35 -0700 X-Complaints-To: abuse@avtel.com X-Trace: newsfeed.avtel.net 962662781 207.71.233.219 (Mon, 03 Jul 2000 15:19:41 PDT) X-Received-Date: Mon, 03 Jul 2000 15:19:41 PDT (newsfeed.avtel.net) To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Please send us your E-mail address. 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Ghosh, Ph.D. Physiologist From owner-cardiors@hgmp.mrc.ac.uk Wed Jul 12 07:08:12 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 0CE9017B3A; Wed, 12 Jul 2000 07:08:11 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 7171A17AA7; Wed, 12 Jul 2000 07:08:10 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id C7277415D5 for ; Wed, 12 Jul 2000 07:08:09 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id HAA24906 for cardiors-list@hgmp.mrc.ac.uk; Wed, 12 Jul 2000 07:08:09 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: Doug Skrecky X-Newsgroups: alt.baldspot,bionet.biology.cardiovascular Subject: spironolactone increases nitric oxide bioactivity Date: 12 Jul 2000 06:02:03 GMT Organization: Vancouver CommunityNet Lines: 33 Message-ID: <8kh1kr$t5l$2@sylvester.vcn.bc.ca> X-Trace: sylvester.vcn.bc.ca 963381723 29877 207.102.64.2 (12 Jul 2000 06:02:03 GMT) X-Complaints-To: sys-admin@vcn.bc.ca User-Agent: tin/pre-1.4-19990805 ("Preacher Man") (UNIX) (SunOS/5.7 (sun4u)) To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Title Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Source Circulation. 101(6):594-7, 2000 Feb 15. Abstract BACKGROUND: The RALES study showed that spironolactone, added to conventional therapy for chronic heart failure, dramatically reduced mortality. We tested the hypothesis that this benefit was partially due to improvement in endothelial function and/or to amplified suppression of the vascular renin-angiotensin axis. METHODS AND RESULTS: We performed a randomized, placebo-controlled, double-blind crossover study on 10 patients with NYHA class II to III chronic heart failure on standard diuretic/ACE inhibitor therapy, comparing 50 mg/d spironolactone (1 month) versus placebo. Forearm vasculature endothelial function was assessed by bilateral forearm venous occlusion plethysmography using acetylcholine and N-monomethyl-L-arginine (L-NMMA), with sodium nitroprusside as a control vasodilator. Also, vascular ACE activity was assessed by use of angiotensin (Ang) I, with Ang II as a control vasoconstrictor. Spironolactone significantly increased the forearm blood flow response to acetylcholine (percentage change in forearm blood flow [mean+/-SEM], 177+/-29% versus 95+/-20%, spironolactone versus placebo; P<0.001), with an associated increase in vasoconstriction due to L-NMMA (-35+/-6% versus -18+/-4%; P<0.05). The Ang I response was also significantly reduced with spironolactone (P<0.05), with Ang II responses unaltered. CONCLUSIONS: Spironolactone improves endothelial dysfunction, increases NO bioactivity, and inhibits vascular Ang I/Ang II conversion in patients with heart failure, providing novel mechanisms for its beneficial effect on cardiovascular mortality. From owner-cardiors@hgmp.mrc.ac.uk Wed Jul 12 07:09:32 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 62A5B17B5D; Wed, 12 Jul 2000 07:09:32 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 65CE917B3A; Wed, 12 Jul 2000 07:09:30 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 9B212415D5 for ; Wed, 12 Jul 2000 07:09:29 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id HAA24911 for cardiors-list@hgmp.mrc.ac.uk; Wed, 12 Jul 2000 07:09:29 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: Doug Skrecky X-Newsgroups: bionet.biology.cardiovascular,sci.life-extension Subject: serum glutathione predicts CHD Date: 12 Jul 2000 06:03:24 GMT Organization: Vancouver CommunityNet Lines: 29 Message-ID: <8kh1nc$t5l$3@sylvester.vcn.bc.ca> X-Trace: sylvester.vcn.bc.ca 963381804 29877 207.102.64.2 (12 Jul 2000 06:03:24 GMT) X-Complaints-To: sys-admin@vcn.bc.ca User-Agent: tin/pre-1.4-19990805 ("Preacher Man") (UNIX) (SunOS/5.7 (sun4u)) To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Title Serum glutathione in adolescent males predicts parental coronary heart disease. Source Circulation. 100(22):2244-7, 1999 Nov 30. Abstract BACKGROUND: Traditional risk factors account for only half of the morbidity and mortality from coronary heart disease (CHD). There is substantial evidence that oxidative injury plays a major role in the atherosclerotic process. Thus, antioxidants may protect against development of atherosclerosis. Glutathione, an intracellular tripeptide with antioxidant properties, may be protective. METHODS AND RESULTS: This case-control study compared total serum glutathione (tGSH) in 81 adolescent male offspring of parents with premature CHD (ie, before 56 years of age) and 78 control male offspring of parents without known or suspected CHD. Case offspring had significantly lower tGSH than control offspring. In multiple logistic regression with parental CHD status as the dependent variable, age entered as a covariate, and other CHD risk factors competing to enter the model as significant independent predictor variables, LDL cholesterol (odds ratio [OR], 2.15 [units=1.5 SD]; 95% CI, 1.21 to 3.82), tGSH (OR, 0.40; 95% CI, 0.22 to 0.71), HDL cholesterol (OR, 0.42; 95% CI, 0.22 to 0.78), and total serum homocysteine (OR, 2.6; 95% CI, 1.35 to 5.02) entered the model as significant predictors of parental CHD status. CONCLUSIONS: Low tGSH in adolescent boys is a significant independent predictor of parental CHD, in addition to elevated LDL cholesterol, low HDL cholesterol, and elevated total serum homocysteine concentrations. From owner-cardiors@hgmp.mrc.ac.uk Thu Jul 13 15:04:11 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 96BC317A9F; Thu, 13 Jul 2000 15:04:10 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 30F7B17A61; Thu, 13 Jul 2000 15:04:09 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id AE9FF415D5 for ; Thu, 13 Jul 2000 15:04:08 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id PAA27042 for cardiors-list@hgmp.mrc.ac.uk; Thu, 13 Jul 2000 15:04:08 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: "Frank" X-Newsgroups: alt.baldspot,bionet.biology.cardiovascular Subject: Re: spironolactone increases nitric oxide bioactivity Date: 13 Jul 2000 14:02:44 GMT Organization: frank Lines: 1 Message-ID: <01bffc9f$bf183ea0$2f6835c3@default> References: <8kh1kr$t5l$2@sylvester.vcn.bc.ca> X-Newsreader: Microsoft Internet News 4.70.1161 To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk any relation with hairloss? From owner-cardiors@hgmp.mrc.ac.uk Thu Jul 13 15:49:43 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 789E917AF5; Thu, 13 Jul 2000 15:49:43 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 2D61E17A9F; Thu, 13 Jul 2000 15:49:42 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 84CD3415D5 for ; Thu, 13 Jul 2000 15:49:41 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id PAA27689 for cardiors-list@hgmp.mrc.ac.uk; Thu, 13 Jul 2000 15:49:40 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: pproctor@proctorgamble.com (Peter H. Proctor) X-Newsgroups: alt.baldspot,bionet.biology.cardiovascular Subject: Re: spironolactone increases nitric oxide bioactivity Date: Thu, 13 Jul 2000 09:57:44 UNDEFINED Organization: Neosoft (using Airnews.net!) Lines: 13 Message-ID: <08AB0FA16DC37799.77B19B085915A740.B200629123EA083F@lp.airnews.net> X-Orig-Message-ID: References: <8kh1kr$t5l$2@sylvester.vcn.bc.ca> <01bffc9f$bf183ea0$2f6835c3@default> Abuse-Reports-To: abuse at airmail.net to report improper postings NNTP-Proxy-Relay: 204.181.96.50 NNTP-Posting-Time: Thu Jul 13 09:48:55 2000 X-Newsreader: Trumpet for Windows [Version 1.0 Rev B final beta #4] To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk In article <01bffc9f$bf183ea0$2f6835c3@default> "Frank" writes: >From: "Frank" >Subject: Re: spironolactone increases nitric oxide bioactivity >Date: 13 Jul 2000 14:02:44 GMT >any relation with hairloss? Nitric Oxide ( "NO", as in miNOxidil ) may be an important mediator of hair growth, in a addition to a bunch of other things. See: http://www.drproctor.com/baldfaq.htm . Dr P From owner-cardiors@hgmp.mrc.ac.uk Wed Jul 19 19:23:27 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 2759917B59; Wed, 19 Jul 2000 19:23:27 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id EA52017AA5; Wed, 19 Jul 2000 19:23:25 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 4EB44415D4 for ; Wed, 19 Jul 2000 19:23:25 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id TAA07167 for cardiors-list@hgmp.mrc.ac.uk; Wed, 19 Jul 2000 19:23:24 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: Doug Skrecky X-Newsgroups: bionet.biology.cardiovascular,sci.life-extension Subject: apoB is extremely low in many Japanese centenarians Date: 19 Jul 2000 18:17:13 GMT Organization: Vancouver CommunityNet Lines: 35 Message-ID: <8l4rb9$t1b$1@sylvester.vcn.bc.ca> X-Trace: sylvester.vcn.bc.ca 964030633 29739 207.102.64.2 (19 Jul 2000 18:17:13 GMT) X-Complaints-To: sys-admin@vcn.bc.ca User-Agent: tin/pre-1.4-19990805 ("Preacher Man") (UNIX) (SunOS/5.7 (sun4u)) To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Title [Lipid and lipoprotein profile of Japanese centenarians--high prevalence of hypo beta lipoproteinemia]. [Japanese] Source Nippon Ronen Igakkai Zasshi - Japanese Journal of Geriatrics. 34(3):202-8, 1997 Mar. Abstract To study the relationship between lipids and longevity, we examined the level of serum lipids and apolipoproteins, and the susceptibility of low density lipoprotein (LDL) to oxidation of 45 centenarians (15 men, 30 women, mean age 101.1 +/- 1.4) living in the Tokyo metropolitan area. The average levels of total cholesterol (TC), of LDL-C of high-density lipoprotein cholesterol (HDL-C), and of apolipoproteins A1 and B were significantly lower in centenarians than in healthy middle-aged controls. The frequency of hypobeta-lipoproteinemia (apoB < 60 mg/dl) in centenarians was almost ten times as high as in controls. The time course of copper-mediated LDL, oxidation (assessed by monitoring 234 nm diene absorption (lag time)) did not significantly differ between the two groups. Analysis of LDL subfractions by non-denaturated gradient-gel electrophoresis showed a predominance of large, buoyant LDL particles (pattern A) in 75%, and a predominance of small dense LDL particles (pattern B) in 25% of centenarians. We also assessed activities of daily living (ADL) and cognitive function in the centenarians. Centenarians were divided into two groups according to the median ADL score, and were classified into five groups with a scale clinical dementia. In subjects with good ADL scores, the mean concentration of HDL-3-C was significantly higher than in those with poor ADL scores. Average levels of HDL-C were also significantly lower in subjects with moderate or severe dementia than in those with normal cognitive function. These findings suggest that centenarians have protective phenotypes of lipids and lipoproteins that protect them from atheroscierosis. From owner-cardiors@hgmp.mrc.ac.uk Fri Jul 21 15:01:29 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id AF13A17AD3; Fri, 21 Jul 2000 15:01:28 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 11CFA17ABD; Fri, 21 Jul 2000 15:01:26 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 6169B415DD for ; Fri, 21 Jul 2000 15:01:26 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id PAA26206 for cardiors-list@hgmp.mrc.ac.uk; Fri, 21 Jul 2000 15:01:25 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: cg707 X-Newsgroups: bionet.biology.cardiovascular Subject: Scientists and web personalisation Date: Fri, 21 Jul 2000 15:01:21 +0100 Organization: City University Lines: 25 Message-ID: <397857B1.1E30F290@city.ac.uk> Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.6 [en-gb] (WinNT; I) X-Accept-Language: en-GB,en,en-* To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Hello, I was wondering if anyone could help me. I am doing a masters research project into web personalisation services like MyYahoo, MyExcite, Crayon, and Dow Jones Clips. I am aiming to assess what people think of these services, whether they help in their work and as regards their need to find information and in relation to the issue of information overload. I would be very grateful if you could take a few minutes to fill in the questionnaire. All returned questionnaires will be put into a prize draw. You can access the questionnaire at the following webaddress: http://www.city.ac.uk/~cg707/pages/websurvey.htm Once you have completed the questionnaire, all you have to do is electronically post back the form by selecting the option to "Post the survey". Thank you very much for your time, Yours, Edwina Wontner MSc Information Systems and Technology, City University, London, UK edwinawontner@hotmail.com From owner-cardiors@hgmp.mrc.ac.uk Sat Jul 22 18:39:06 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 8CB0317B26; Sat, 22 Jul 2000 18:39:05 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 64BE917B24; Sat, 22 Jul 2000 18:39:04 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id D5D0A415DD for ; Sat, 22 Jul 2000 18:39:03 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id SAA24767 for cardiors-list@hgmp.mrc.ac.uk; Sat, 22 Jul 2000 18:39:03 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: info4me@myrealbox.com X-Newsgroups: bionet.biology.cardiovascular Subject: Earn 150k Your First Year!! 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To be removed from our mailing list please send an email to: listremoval@unbounded.com and place remove in the subject Thank you ********************************************************* --- From owner-cardiors@hgmp.mrc.ac.uk Mon Jul 24 05:43:02 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 4776A17A96; Mon, 24 Jul 2000 05:43:02 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 289DD17A93; Mon, 24 Jul 2000 05:43:01 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 86E62415DC for ; Mon, 24 Jul 2000 05:43:00 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id FAA06783 for cardiors-list@hgmp.mrc.ac.uk; Mon, 24 Jul 2000 05:43:00 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: greatbiz2000@myrealbox.com X-Newsgroups: bionet.biology.cardiovascular Subject: Fantastic Home Based Opportunity!!!! Date: 24 Jul 2000 05:42:59 +0100 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 77 Message-ID: <20000724044255.E1474415DC@mercury.hgmp.mrc.ac.uk> X-Trace: niobium.hgmp.mrc.ac.uk 964413779 6781 193.62.192.80 (24 Jul 2000 04:42:59 GMT) X-Complaints-To: news@net.bio.net X-Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 0EA0617A93; Mon, 24 Jul 2000 05:42:57 +0100 (BST) X-Received: from dns.netmark.ne.jp (dns.yakult21.co.jp [210.164.151.115]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id E1474415DC for ; Mon, 24 Jul 2000 05:42:55 +0100 (BST) X-Received: from ts014d03.phx-az.concentric.net by dns.netmark.ne.jp with SMTP (Microsoft Exchange Internet Mail Service Version 5.0.1460.8) id 32HYVD2Q; Mon, 24 Jul 2000 13:23:14 +0900 X-To: dfsls@fjlesjd.it To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk LOOKING FOR GEMS! It's so simple To Earn $2,000 - $5,000 Per Week Nowadays... 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To be removed from our mailing list please send an email to: listremoval@unbounded.com and place remove in the subject Thank you ********************************************************* --- From owner-cardiors@hgmp.mrc.ac.uk Tue Jul 25 07:27:44 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 0577717B04; Tue, 25 Jul 2000 07:27:43 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id A26F417ABE; Tue, 25 Jul 2000 07:27:42 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id CD323415D4 for ; Tue, 25 Jul 2000 07:27:41 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id HAA14655 for cardiors-list@hgmp.mrc.ac.uk; Tue, 25 Jul 2000 07:27:41 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: info4me@myrealbox.com X-Newsgroups: bionet.biology.cardiovascular Subject: Earn 150k Your First Year!! Date: 25 Jul 2000 07:27:39 +0100 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 58 Message-ID: <20000725062736.02665415D4@mercury.hgmp.mrc.ac.uk> X-Trace: niobium.hgmp.mrc.ac.uk 964506460 14653 193.62.192.80 (25 Jul 2000 06:27:40 GMT) X-Complaints-To: news@net.bio.net X-Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 2065317B38; Tue, 25 Jul 2000 07:27:37 +0100 (BST) X-Received: from rubis.intra.quebec-amerique.com (unknown [206.162.176.146]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 02665415D4 for ; Tue, 25 Jul 2000 07:27:35 +0100 (BST) X-Received: from default (ts002d48.phx-az.concentric.net [208.176.168.108]) by rubis.intra.quebec-amerique.com with SMTP (Microsoft Exchange Internet Mail Service Version 5.5.2650.21) id 3ZHXJWSX; Sat, 22 Jul 2000 12:37:40 -0400 X-To: dfsls@fjlesjd.it To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Hello, I'll get right to the point. 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In fact, I'm so sure that I can do so, I am willing to put my money where my mouth is! Upon accepting you as a member of my team, I will provide you with complete training and advertising assistance to help put you on the road to success. Call 1-800-320-9895 Ext. 6131 (Free Recorded Message) Prosperous Regards ********************************************************************** All REMOVE requests AUTOMATICALLY honored upon receipt. PLEASE understand that any effort to disrupt, close or block this REMOVE account can only result in difficulties for others wanting to be removed from our mailing list as it will be impossible to take anyone off the list if the remove instruction can not be received. To be removed from our mailing list please send an email to: listremoval@unbounded.com and place remove in the subject Thank you ********************************************************* --- From owner-cardiors@hgmp.mrc.ac.uk Thu Jul 27 16:00:13 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id B868117BC4; Thu, 27 Jul 2000 16:00:12 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 2F21817BC3; Thu, 27 Jul 2000 16:00:10 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 48657415DA for ; Thu, 27 Jul 2000 16:00:10 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id QAA13770 for cardiors-list@hgmp.mrc.ac.uk; Thu, 27 Jul 2000 16:00:09 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: lliberti@my-deja.com X-Newsgroups: bionet.biology.cardiovascular Subject: New news summaries on cardiology web site Date: Thu, 27 Jul 2000 14:47:18 GMT Organization: Deja.com - Before you buy. Lines: 33 Message-ID: <8lpi1k$jhp$1@nnrp1.deja.com> X-Article-Creation-Date: Thu Jul 27 14:47:18 2000 GMT X-Http-User-Agent: Mozilla/4.0 (compatible; MSIE 5.0; Windows NT; DigExt) X-Http-Proxy: 1.1 x70.deja.com:80 (Squid/1.1.22) for client 151.197.122.34 X-MyDeja-Info: XMYDJUIDlliberti To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk CardioExchange is a web site for cardiovascular researchers and clinicians. The site includes: „h topical news summaries about advances in the diagnosis, prevention, and treatment of cardiovascular diseases „h interactive self-guided clinical cases presented by nationally- recognized cardiovascular specialists „h a newsletter series that provides highlights from key international scientific meetings with all past issues archived on this site „h a moderated discussion group for clinicians The topical news summaries for the month of May are now available online at CardioExchange, so be sure to check them out. While you¡¦re there, why not sign up for our moderated discussion group to experience high-level interactions with other cardiovascular professionals and to receive periodic e-mail alerts when new material becomes available on CardioExchange. We hope that you will find the CardioExchange site to be among the most interesting and clinically relevant cardiology sites available on the Internet. Visit CardioExchange at http://www.cardioexchange.com today! Sincerely, Lawrence E. Liberti, MSc, RPh President Pharmaceutical Information Associates, Ltd P: 215-949-0490 F: 215-949-2594 Sent via Deja.com http://www.deja.com/ Before you buy. From owner-cardiors@hgmp.mrc.ac.uk Fri Jul 28 20:45:13 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id D3B9217A69; Fri, 28 Jul 2000 20:45:12 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 8332A17B0A; Fri, 28 Jul 2000 20:45:11 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 6D4D8415DA for ; Fri, 28 Jul 2000 20:45:10 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id UAA13539 for cardiors-list@hgmp.mrc.ac.uk; Fri, 28 Jul 2000 20:45:09 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: smisba@west.net (Herman Barrantes) X-Newsgroups: alt.russia,alt.sci,alt.taiwan,be.science,bionet.biology.cardiovascular, Subject: Clinical Laboratory Message-ID: Organization: SMI Lines: 34 Date: Fri, 28 Jul 2000 12:40:58 -0700 X-Complaints-To: abuse@avtel.com X-Trace: newsfeed.avtel.net 964813496 207.71.233.219 (Fri, 28 Jul 2000 12:44:56 PDT) X-Received-Date: Fri, 28 Jul 2000 12:44:56 PDT (newsfeed.avtel.net) To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk If you would like to begin receiving, CLINICA, a FREE, NO OBLIGATION E-mail Newsletter, please send us your E-mail address. Periodically we will prepare different articles on medical history, tales of medical detection, special foods, wines and travel. We hope you enjoy them and invite you to share with a friend. We've included a list of available issues. Just let us know which one interests you. Thank you and enjoy ! Francisco Pizarro / Gunshot Wounds / Hepatitis / Latin America Medical History 1 & 2 / The Eiffel Tower / Torcolato Wine / New Zealand Gloworm Caves ----------------------------------------------------------------------------- If you would also like to receive COLOR PHOTOS (again under no OBLIGATION) and Product Information of the following clinical laboratory products, please let us know. A. Monoclonal Antisera for ABO and Rare Blood Typing (NUBIO) B. SUPREME Petit Blood Glucose Meter: Determines Blood Glucose levels rapidly and quantitively. The system has been on the market for several years. It is now available in Latin America, Europe, the Far and Middle East. (SYNTRON) C. 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Sincerely, Director SMI From owner-cardiors@hgmp.mrc.ac.uk Sat Jul 29 01:02:16 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 99E7317A59; Sat, 29 Jul 2000 01:02:15 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 1FD9717A5B; Sat, 29 Jul 2000 01:02:13 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 4EECC415DD for ; Sat, 29 Jul 2000 01:02:13 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id BAA25100 for cardiors-list@hgmp.mrc.ac.uk; Sat, 29 Jul 2000 01:02:12 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: A.Shameli@btinternet.com (Ashley Shameli) X-Newsgroups: uk.people.health,sci.med.cardiology,own.health.misc,misc.health,bionet.biology.cardiovascular,alt.support-heart,alt.support.heart-defects Subject: Low Blood Pressure post AORTIC VALVE surgery - Help and Advice needed urgently Date: Thu, 27 Jul 2000 23:48:51 GMT Organization: BT Internet Lines: 29 Message-ID: <3987c8f6.648903@news.btinternet.com> Reply-To: A.Shameli@btinternet.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Newsreader: Forte Agent .99g/32.339 To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Hello members, My mother, three/four days post op (on Monday GMT 4PM) had her aortic valve replaced at Queen Elizabeth Hospital, Birmingham, by Mr Keogh, with a carbon fibre St.Jude valve (possibly not a St.Jude but definatly mechanical). She seemed to come out of intensive care well, but has spent a long time (nearly three days) in the high-dependance ward (the second stage of monitoring here in the UK) while other patients have spent only a day or two, because her blood pressure is still low. I am not sure exactly what it is, but the surgeon said it is low because her heart was so swollen when they operated, and they hope the heart will return to its normal shape and as a result the blood pressure return to normal. Now, they are not sure that the heart will return to normal, and while her blood pressure doesn't drop as they wean her off her drugs neither has it risen. Is this in any way normal, and can anyone spread any light on this mystery to put our minds at rest. Thanks a lot, Ashley a.shameli@btinternet.com From owner-cardiors@hgmp.mrc.ac.uk Sat Jul 29 19:13:49 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 975A517AA5; Sat, 29 Jul 2000 19:13:48 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 48EB317A9C; Sat, 29 Jul 2000 19:13:46 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 110A2415D4 for ; Sat, 29 Jul 2000 19:13:45 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id TAA07916 for cardiors-list@hgmp.mrc.ac.uk; Sat, 29 Jul 2000 19:13:45 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: fmorales X-Newsgroups: uk.people.health,sci.med.cardiology,own.health.misc,misc.health,bionet.biology.cardiovascular,alt.support-heart,alt.support.heart-defects Subject: Re: Low Blood Pressure post AORTIC VALVE surgery - Help and Advice needed urgently Date: Sat, 29 Jul 2000 13:21:17 -0700 Organization: http://members.tripod.com/mor_f/index.htm UPDATED 7-28-2000 Lines: 40 Message-ID: <39833CBD.BEE3D8A8@hotmail.com> References: <3987c8f6.648903@news.btinternet.com> Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Trace: Masala.CC.UH.EDU 964894421 29232 129.7.65.120 (29 Jul 2000 18:13:41 GMT) X-Complaints-To: abuse@UH.EDU X-Mailer: Mozilla 4.7 [en] (Win98; I) X-Accept-Language: en To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk hello, i am writing to you in reply: i have a g-mother who had this same operation in Seattle here in the States. Same results. it took some time but recovery ensued and she is on medication to 'raise' her BP a little. she has lived eight more years and still going strong. her meds give her a little edema but she says 'still around to enjoy family so it is worth it.' best of luck. fm Ashley Shameli wrote: > Hello members, > > My mother, three/four days post op (on Monday GMT 4PM) had her aortic > valve replaced at Queen Elizabeth Hospital, Birmingham, by Mr Keogh, > with a carbon fibre St.Jude valve (possibly not a St.Jude but > definatly mechanical). > > She seemed to come out of intensive care well, but has spent > a long time (nearly three days) in the high-dependance ward (the > second stage of monitoring here in the UK) while other patients have > spent only a day or two, because her blood pressure is still low. > > I am not sure exactly what it is, but the surgeon said it is low > because her heart was so swollen when they operated, and they > hope the heart will return to its normal shape and as a result the > blood pressure return to normal. > > Now, they are not sure that the heart will return to normal, and while > her blood pressure doesn't drop as they wean her off her drugs neither > has it risen. > > Is this in any way normal, and can anyone spread any light on this > mystery to put our minds at rest. > > Thanks a lot, > Ashley > > a.shameli@btinternet.com From owner-cardiors@hgmp.mrc.ac.uk Sun Jul 30 12:31:12 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 2264E17A99; Sun, 30 Jul 2000 12:31:12 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id B26ED17A97; Sun, 30 Jul 2000 12:31:10 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 11C31415CF for ; Sun, 30 Jul 2000 12:31:09 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id MAA28884 for cardiors-list@hgmp.mrc.ac.uk; Sun, 30 Jul 2000 12:31:09 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: A.Shameli@btinternet.com (Ashley Shameli) X-Newsgroups: uk.people.health,sci.med.cardiology,own.health.misc,misc.health,bionet.biology.cardiovascular,alt.support-heart,alt.support.heart-defects Subject: Alternatives to WARFARIN - re: aortic valve surgery Date: Sun, 30 Jul 2000 11:28:13 GMT Organization: BT Internet Lines: 8 Message-ID: <39851117.45956251@news.btinternet.com> Reply-To: A.Shameli@btinternet.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Newsreader: Forte Agent .99g/32.339 To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk Hello, Could anyone point me in the way of information / web links about possible alternatives to Warfarin, (probably still being developed) which are safter to take? (if such a thing does exist) Thanks, Ashley. From owner-cardiors@hgmp.mrc.ac.uk Mon Jul 31 14:00:09 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id DA2A417AB5; Mon, 31 Jul 2000 14:00:08 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6024) id 7560517A99; Mon, 31 Jul 2000 14:00:07 +0100 (BST) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id D2854415D4 for ; Mon, 31 Jul 2000 14:00:06 +0100 (BST) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id OAA25640 for cardiors-list@hgmp.mrc.ac.uk; Mon, 31 Jul 2000 14:00:06 +0100 (BST) X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: Andy Anderson X-Newsgroups: uk.people.health,sci.med.cardiology,own.health.misc,misc.health,bionet.biology.cardiovascular,alt.support-heart,alt.support.heart-defects Subject: Re: Alternatives to WARFARIN - re: aortic valve surgery Date: Mon, 31 Jul 2000 13:57:01 +0100 Organization: leptis Message-ID: References: <39851117.45956251@news.btinternet.com> X-NNTP-Posting-Host: aicuk.demon.co.uk:158.152.140.10 X-Trace: news.demon.co.uk 965048342 nnrp-07:11427 NO-IDENT aicuk.demon.co.uk:158.152.140.10 X-Complaints-To: abuse@demon.net MIME-Version: 1.0 X-Newsreader: Turnpike Integrated Version 4.02 U Lines: 21 To: cardiors@hgmp.mrc.ac.uk Sender: owner-cardiors@hgmp.mrc.ac.uk Precedence: bulk In article <39851117.45956251@news.btinternet.com>, Ashley Shameli writes >Hello, > >Could anyone point me in the way of information / web links about >possible alternatives to Warfarin, (probably still being developed) >which are safter to take? (if such a thing does exist) > >Thanks, >Ashley. Hi Ashley, I`m so pleased you mum has at LAST had her surgery but what a long wait for you all! Good luck. Go to: www.google.co.uk and do a search. I`ve just done it by using the words " alternative warfarin heart patients" A lot of info. came up which may help. Google seems like a great place for info. searching. pat@aicuk.demon.co.uk I`m still checking my husband`s heart NG! Pat -- Andy Anderson