From owner-chromosomes@net.bio.net Sat Mar 02 22:00:00 1996 Path: biosci!agate!howland.reston.ans.net!math.ohio-state.edu!jussieu.fr!rain.fr!news From: dgieff@mail.sdv.fr (Didier Georgieff) Newsgroups: bionet.genome.chromosomes,sci.med Subject: Looking for Trisomy 1 info Date: Sun, 03 Mar 1996 21:43:17 GMT Organization: Christian Debs (Strasbourg Medical University - France) Lines: 21 Message-ID: <4hd7j7$gvr@obelix.rain.fr> NNTP-Posting-Host: sdvip09.sdv.fr Keywords: health trisomy X-Newsreader: Forte Free Agent 1.0.82 Xref: biosci bionet.genome.chromosomes:1055 sci.med:113300 Hi, I'm involved in research for trisomy 1 (q 32 q ter) for completing a case study. I looked a www pages via search engine, but found nothing. So i try usenet. I'm particulary interested in biography, article reference ans especially in case study. If any physician had such patient, i greatly appreciate any info on the age, the patology, and any special thing with that trisomy. If you are interested in such case, i can (when the article will be over) send clinical observations about the case we are studing. PS : I'm french so .... don't pay attention to that special kind of english :-) -- Didier Georgieff -/- dgieff@mail.sdv.fr -/- DDAF du Bas-Rhin, France From owner-chromosomes@net.bio.net Sat Mar 02 22:00:00 1996 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.genome.chromosomes Subject: AUTOMATED-SEQUENCING/bionet.genome.autosequencing PASSES: 197-3 Date: 3 Mar 1996 15:32:52 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 96 Sender: biohelp@net.bio.net Distribution: world Message-ID: <4hda74$lq@net.bio.net> NNTP-Posting-Host: net.bio.net I am pleased to announce that the proposal to create the mailing list & newsgroup AUTOMATED-SEQUENCING/bionet.genome.autosequencing (moderated) passed by 197 YES votes to 3 NO votes. We will proceed to create this group as soon as possible. E-mail users: please wait until you see an announcement in BIONEWS/bionet.announce that the group is ready for operation before you request an e-mail subscription. Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net ---------------------------------------------------------------------- Proposal to create AUTOMATED-SEQUENCING/bionet.genome.autosequencing (moderated) USENET newsgroup name: bionet.genome.autosequencing Status: Moderated One line Description: Research and support on automated DNA sequencing Moderation address: bionet-genome-autosequencing@net.bio.net (autoseq-moderator@net.bio.net is an alias for bionet-genome-autosequencing@net.bio.net) Administrator: David Cain Mailing list name: AUTOMATED-SEQUENCING E-mail addresses: autoseq@net.bio.net autoseq@daresbury.ac.uk Newsgroup character: AUTOMATED-SEQUENCING/bionet.genome.autosequencing is a forum for the concentrated discussion and source of assistance on issues relating to automated DNA sequencing and fragment analysis such as microsatellite analysis and SSCP . AUTOMATED-SEQUENCING has been chosen as the name to represent the many different systems currently avaliable . Functions of the newsgroup: The newsgroup will offer a well needed focus for the discussion of automated DNA sequencing / fragment analysis which has until now been spread across a number of newsgroups resulting in many cross postings . The newsgroup will replace the one currently running on mailbase which has been running for just under a year and proaved to be well supported . Topics for discussion will include sequencing chemistries , template preparation methods , hints and tips for optimisation , recommended protocols for both large and small scale projects as well as providing a forum for support between scientists. Other aspects of the post-sequencing process will also be dealt with, for example, sequence troubleshooting and software issues. The newsgroup will also serve as a bulletin board for the announcement of meetings , conferences , job opportunities within the rapidly expanding sequencing market . Subscriptions are welcome from all academic institutions , hospitals , government agencies and other research facilities as well as commercial and industrial organisations . Contributions which support the outlined functions of the newsgroup will be actively encouraged . Moderation Policy: Chain letters , mass posted commercial messages and other messages deemed to be "Junk mail" will be deleted without comment . Inappropriate messages for commercial or legal reasons will be returned to the originator for editing and re-submission . Messages which are not strictly within the terms of the charter but still deemed to be of interest to the subscribers will be accepted as long as they do not breach any of the terms and conditions of the charter . Due to the commercial competitive nature of the subject companies with a vested interest will be encouraged to limit their activities on the newsgroup to replying directly to questions posted or clearing an article with the moderators prior posting to the list. Advertisements for commercial products are prohibited on the BIOSCI/bionet newsgroups. Proposed Moderators David Cain DNA sequencing Unit , Institute of Cancer Research , Chester Beatty Labs , London , UK Robert Feakes Department of Genetics , University of Cambridge , Cambridge , UK ---------------------------------------------------------------------- From owner-chromosomes@net.bio.net Mon Mar 04 22:00:00 1996 Path: biosci!ODYSSEE.NET!dellaire From: dellaire@ODYSSEE.NET (Graham Dellaire) Newsgroups: bionet.genome.chromosomes Subject: FISH probes for Murine alpha satellite DNA? WHo sells them (or reference) Date: 4 Mar 1996 19:44:15 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 14 Sender: daemon@net.bio.net Distribution: world Message-ID: <313BB74B.53C5@odyssee.net> NNTP-Posting-Host: net.bio.net Hello, I am trying to do a karyotype of a murine cells line (LTA(a derivative of L M tk- ) that appears to have quite a few anomolies. Does anyone know of a company ( or the ref on a paper) that sells paints for alphoid DNA or for murine centromeres? Thanks Graham dellaire@odyssee.net From owner-chromosomes@net.bio.net Wed Mar 06 22:00:00 1996 Path: biosci!SURGERY.BSD.UCHICAGO.EDU!ewhite From: ewhite@SURGERY.BSD.UCHICAGO.EDU (Eileen White) Newsgroups: bionet.genome.chromosomes Subject: mouse chr 11and human chr 17 Date: 7 Mar 1996 09:56:14 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 5 Sender: daemon@net.bio.net Distribution: world Message-ID: <199603071756.LAA19772@surgery.bsd.uchicago.edu> NNTP-Posting-Host: net.bio.net I am trying to locate any individuals or labs that are currently studying the region of mouse chr 11 that shares homology with human chr 17p. Any e-mail addresses or phone numbers would be greatly appreciated. Eileen White From owner-chromosomes@net.bio.net Wed Mar 06 22:00:00 1996 Path: biosci!genetics.adelaide.edu.au!rsaint From: rsaint@genetics.adelaide.edu.au Newsgroups: bionet.genome.chromosomes Subject: Faculty Positions in Genetics Date: 6 Mar 1996 23:15:55 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 50 Sender: daemon@net.bio.net Distribution: world Message-ID: <01I22DGMTQNAB7CCXL@mulga.itd.adelaide.edu.au> NNTP-Posting-Host: net.bio.net TWO LECTURESHIPS IN GENETICS Applications are invited for two Lectureships in genetics in the Department of Genetics, University of Adelaide, Australia. Lecturer (tenurable) (Ref: 8893) Lecturer (limited term, 3 years) (Ref: 8892) The successful applicants, who will have an appropriate doctoral degree (or equivalent qualification) and a record of productive and innovative research, will be expected to establish vibrant research programs and teach in various undergraduate genetics courses. Research areas of particular interest are those that strengthen or extend current areas of expertise within the Department and that will provide high quality training for postgraduate students. These include (but are not limited to) any aspect of human genetics, neurogenetics, behavioural genetics, genome and chromosome structure and function, gene expression and developmental genetics. It is expected that one of the two appointees will be actively involved in human genetics research. The Department of Genetics has excellent postgraduate and research programs with strengths in gene expression, chromosome structure, developmental genetics, cell cycle genetics, evolutionary genetics and genetic engineering of plants and microbes. Affiliates include members of the Department of Cytogenetics and Molecular Genetics, the Women's and Children's Hospital, the Evolutionary Biology Unit of the South Australian Museum and the South Australian Forensic Science Centre. The positions are available from 1 July 1996. Further details about the Department and duties of the positions, including a selection criteria, may be obtained from Professor Robert Saint, Department of Genetics, telephone 61-8-303 4043, facsimile 61-8-303 4399 or via http:// www.science.adelaide.edu.au/genetics/home.html. Salary per annum: Lecturer (Level B): Aust$42,198 - $50,111 Applications, in duplicate, quoting reference numbers 8893/8892 and giving full personal particulars (including whether candidates hold Australian permanent residency status), details of qualifications, current salary and names and full addresses of three referees should reach the Director, Personnel Services, University of Adelaide, Australia 5005, no later than 12 April 1996. Applicants should clearly address the selection criteria in their applications. The University reserves the right to make enquiries of any person regarding any candidate's suitability for appointment, not to make an appointment or to appoint by invitation. The university of adelaide is an equal opportunity employer. From owner-chromosomes@net.bio.net Wed Mar 06 22:00:00 1996 Path: biosci!lhc.nlm.nih.gov!darwin.sura.net!news.sesqui.net!news.ti.com!news.dseg.ti.com!news From: shelton@adrs1.dseg.ti.com (Anne Shelton) Newsgroups: bionet.genome.chromosomes Subject: Genetics questions Date: 7 Mar 1996 18:55:01 GMT Lines: 22 Distribution: world Message-ID: <4hnbe5$l4g@mksrv1.dseg.ti.com> Reply-To: shelton@adrs1.dseg.ti.com NNTP-Posting-Host: adr15.dseg.ti.com 1) In another newsgroup, the question of eye color came up. How many genes does it take to determine eye color. I know there's more than 1 because there are many shades and different eye colors. Some people can't get over high school biology: Brown is dominant over blue. Some references and quotable sources would help. 2) Second Question: is the X sex chromosome required for viability? A single X (Turner's Syndrome) is a sterile female but are there any single Y syndromes (living)? If so, what is it called and what are the syndrome effects? 3) Third Question: In the Trisomy combinations of the sex chromosomes, XXX, XXY, XYY, (YYY?) what are the different effects of these genetic combinations? (i.e. XYY = aggressive male) I hope someone with firsthand knowledge out there can provide the answers to the above questions. Thanks in advance. Regards, Anne Shelton From owner-chromosomes@net.bio.net Thu Mar 07 22:00:00 1996 Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!usenet From: line.roed@kjemi.uio.no (Line R|ed) Newsgroups: bionet.genome.chromosomes Subject: Primers for PCR? Date: 8 Mar 1996 10:01:26 GMT Organization: Universitet i Oslo Lines: 18 Message-ID: <4hp0hm$l5f@ratatosk.uio.no> NNTP-Posting-Host: pckjemi103.uio.no Mime-Version: 1.0 Content-Type: Text/Plain; charset=US-ASCII X-Newsreader: WinVN 0.99.7 Hi! We are to do PCR on whole blood from dogs. We have no information on sequences, restriction maps or anything - all we want is to get a PCR product of reasonable length (1000-2000 bp). Is there anyone who could suggest what primers to use? We have considered using random primers of ca. length 12 bp. Are there any other suggestions? Please mail us directly: line.roed@kjemi.uio.no Regards, Irina Arsky and Line Roed From owner-chromosomes@net.bio.net Fri Mar 08 22:00:00 1996 Path: biosci!agate!howland.reston.ans.net!news-e2a.gnn.com!newstf01.news.aol.com!newsbf02.news.aol.com!not-for-mail From: rcjohnsen@aol.com (Rcjohnsen) Newsgroups: bionet.genome.chromosomes Subject: Re: Genetics questions Date: 8 Mar 1996 18:41:45 -0500 Organization: America Online, Inc. (1-800-827-6364) Lines: 21 Sender: root@newsbf02.news.aol.com Message-ID: <4hqgjp$fiq@newsbf02.news.aol.com> References: <4hnbe5$l4g@mksrv1.dseg.ti.com> Reply-To: rcjohnsen@aol.com (Rcjohnsen) NNTP-Posting-Host: newsbf02.mail.aol.com Reply to asking 3 genetics questions: I doubt there's an answer to the first question about the number of genes controlling eye color. Eye color appears to dependent upon the number, shape, and size of pigment granules in the iris as well as the type and amount of pigment deposited on them. The number of genes controlling this is speculative. On the second question about the X chromosome necessary for viability, the answer is, most definitely yes. Research in Drosophila and mice where 0/Y zygotes can be produced experimentally shows that such zygotes die in the early stages of zygotic division. Hence, most scientists feel this is true for 0/Y human zygotes too and you might find something more concrete about it in a University or good community library with journals on in vitro fertilization research. The NY Academy of Sciences has published a couple of volumes on this research. On the third question, there is a lot of literature on the various syndromes you had questions about. I suggest you try searching Searching OMIM Using Fill-In Forms http://gdbwww.gdb.org/omim-bin/omim/bin/omimq an online searchable database in human genetics. Rcjohnsen@aol.com From owner-chromosomes@net.bio.net Sat Mar 09 22:00:00 1996 Path: biosci!CS.Arizona.EDU!noao!ennfs.eas.asu.edu!gatech!newsfeed.internetmci.com!usenet.eel.ufl.edu!psgrain!nntp.teleport.com!usenet From: saramac@teleport.com Newsgroups: bionet.genome.chromosomes Subject: Congenital Hypothyroidism Date: 10 Mar 1996 03:16:30 GMT Organization: Teleport - Portland's Public Access (503) 220-1016 Lines: 8 Distribution: world Message-ID: <4hthie$fgh@nadine.teleport.com> NNTP-Posting-Host: ip-pdx04-22.teleport.com X-Newsreader: AIR News 3.X (SPRY, Inc.) I'm looking for information on this one. The symptoms: an underdeveloped/atrophied thyroid gland, unable to produce any thyroxine. What chromosome does it happen on???? Poly From owner-chromosomes@net.bio.net Sat Mar 09 22:00:00 1996 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.genome.chromosomes Subject: AUTOMATED-SEQUENCING/bionet.genome.autosequencing is ready! Date: 10 Mar 1996 14:29:23 -0800 Organization: BIOSCI International Newsgroups for Biology Lines: 330 Sender: biohelp@net.bio.net Distribution: world Message-ID: <4hvl43$nc5@net.bio.net> NNTP-Posting-Host: net.bio.net The AUTOMATED-SEQUENCING/bionet.genome.autosequencing newsgroup is ready for operation. This newsgroup is moderated, i.e., all postings are forwarded to a moderator/editor and are reviewed prior to distribution. The newsgroup charter is appended below followed by detailed usage instructions and information on how to search the newsgroup archives. *Please save* this message for future reference if you intend to participate in this newsgroup. IMPORTANT - All member's of David Cain's autoseq mailing list (regardless of their geographical location) have been added to the autoseq mailing list at net.bio.net. If you were on that mailing list and would prefer to access this group through USENET (check first and make sure that it has been set up properly at your site!!) or through the WWW at http://www.bio.net, you can cancel your e-mail subscription by sending a message addressed to biosci-server@net.bio.net containing the line unsubscribe autoseq Please put the command in the body of the message. The server ignores the Subject: line of your mail. This will only succeed if the address on your mail matches the address on the mailing list at net.bio.net. If you have problems or get a message saying that you were not on the list (because the addresses did not match exactly), please contact biosci-help@net.bio.net for human assistance. If you want to receive messages by e-mail, but reside in Europe, Africa, or Central Asia, you may want to cancel your e-mail subscription as described above, and sign up at our UK distribution site as detailed further below. ---------------------------------------------------------------------- Information for AUTOMATED-SEQUENCING/bionet.genome.autosequencing (moderated) USENET newsgroup name: bionet.genome.autosequencing Status: Moderated One line Description: Research and support on automated DNA sequencing Moderation address: bionet-genome-autosequencing@net.bio.net (autoseq-moderator@net.bio.net is an alias for bionet-genome-autosequencing@net.bio.net) Moderator: David Cain Mailing list name: AUTOMATED-SEQUENCING E-mail addresses: autoseq@net.bio.net autoseq@daresbury.ac.uk Newsgroup character: AUTOMATED-SEQUENCING/bionet.genome.autosequencing is a forum for the concentrated discussion and source of assistance on issues relating to automated DNA sequencing and fragment analysis such as microsatellite analysis and SSCP. AUTOMATED-SEQUENCING has been chosen as the name to represent the many different systems currently avaliable. Functions of the newsgroup: The newsgroup will offer a well needed focus for the discussion of automated DNA sequencing / fragment analysis which has until now been spread across a number of newsgroups resulting in many cross postings. The newsgroup will replace the one currently running on mailbase which has been running for just under a year and proaved to be well supported. Topics for discussion will include sequencing chemistries , template preparation methods , hints and tips for optimisation , recommended protocols for both large and small scale projects as well as providing a forum for support between scientists. Other aspects of the post-sequencing process will also be dealt with, for example, sequence troubleshooting and software issues. The newsgroup will also serve as a bulletin board for the announcement of meetings , conferences , job opportunities within the rapidly expanding sequencing market. Subscriptions are welcome from all academic institutions , hospitals , government agencies and other research facilities as well as commercial and industrial organisations. Contributions which support the outlined functions of the newsgroup will be actively encouraged. Moderation Policy: Chain letters , mass posted commercial messages and other messages deemed to be "Junk mail" will be deleted without comment. Inappropriate messages for commercial or legal reasons will be returned to the originator for editing and re-submission. Messages which are not strictly within the terms of the charter but still deemed to be of interest to the subscribers will be accepted as long as they do not breach any of the terms and conditions of the charter. Due to the commercial competitive nature of the subject companies with a vested interest will be encouraged to limit their activities on the newsgroup to replying directly to questions posted or clearing an article with the moderators prior posting to the list. Advertisements for commercial products are prohibited on the BIOSCI/bionet newsgroups. Moderators: David Cain DNA sequencing Unit , Institute of Cancer Research , Chester Beatty Labs , London , UK Robert Feakes Department of Genetics , University of Cambridge , Cambridge , UK ---------------------------------------------------------------------- SUBSCRIPTION/USAGE INFORMATION All BIOSCI/bionet newsgroups are now accessible via the World Wide Web. Please go to URL http://www.bio.net, click on the "Access the BIOSCI/bionet Newsgroups" option, and then click on the AUTOMATED-SEQUENCING/bionet.genome.autosequencing hyperlink. You can read, reply to, or post new messages through our Web site if your Web browser is configured properly to send e-mail. If you prefer to use your local USENET newsreader, PLEASE NOTE that many USENET sites do not allow automatic creation of new USENET groups!!! If you do not see bionet.genome.autosequencing in your newsreader within another day or two, ask your news system administrator to act on our "newgroup" message to enable the group at your site. We have already done several tests and are certain that the group is currently propagating around the network. If he/she can not find the newsgroup message, have them retrieve the bionet checkgroups message from URL ftp://net.bio.net/pub/BIOSCI/doc/bionet-checkgroups-msg This file contains the latest list of bionet USENET newsgroups and can be used to update your bionet distribution. 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How to look at archives of the list: ------------------------------------ Archives for AUTOMATED-SEQUENCING/bionet.genome.autosequencing are available on the World Wide Web at URL http://www.bio.net. Please look under the "Access the BIOSCI/bionet Newsgroups" hypertext link and then click on the AUTOMATED-SEQUENCING/bionet.genome.autosequencing hyperlink. Each monthly archive directory is assigned a date such as 9509 for September 1995. You can read, reply to, or post new messages through our Web site if your Web browser is configured properly to send e-mail. Postings to bionet.genome.autosequencing are also indexed and can be searched at our site. Once again, if you have any administrative questions that require personal assistance, please address them to biosci-help@net.bio.net in the U.S. or biosci@daresbury.ac.uk in the UK. Best wishes for a successful newsgroup! Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net From owner-chromosomes@net.bio.net Sun Mar 10 22:00:00 1996 Path: biosci!rutgers!uwm.edu!lll-winken.llnl.gov!fnnews.fnal.gov!nntp-server.caltech.edu!news From: "Dr. Ung-Jin Kim" Newsgroups: bionet.genome.chromosomes Subject: Caltech: lab assistants and a bioinformatician Date: Mon, 11 Mar 1996 10:46:06 -0800 Organization: Division of Biology, Caltech Lines: 48 Message-ID: <314474EE.5BC1@ash.tree.caltech.edu> NNTP-Posting-Host: apple.tree.caltech.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.4 sun4m) Genome Research Laboratory at Caltech: Please see our WEB page, http://www.tree.caltech.edu Job 1: We are looking for a few lab assistants Caltech Genome Resaerch Laboratory is looking for qualified full time technicians with experiences in laboratory works involving recombinant DNA procedures. Works will require skills in colony hybridization, PCR screening of genomic libraries, DNA preparation, restriction fingerprint analysis, and more. Positions are open immediately. College or higher degrees in Biological sciences or other sciences required. Interested parties should send cv to Dr. Ung-Jin Kim. Electronic submissions are welcome. Job 2: We are looking for a bioinformatician Caltech Genome Research Laboratory is looking for a full time informatician to manage and analyze laboratory data, and help operate robotic workstations. Knowledge and experieince in handling biological information, especially in the analysis and management of physcal mapping and DNA sequence data is essential. We also expect the person to be familiar with Unix server/workstations and PC/MacIntosh platforms. Interested parties should send CV to Dr. Ung-Jin Kim. Electronic submissions are welcome. We will notify the applicants if an interview is necessary soon after reviewing their applications. Ung-Jin Kim, Ph.D. 147-75, Division of Biology, Caltech, Pasadena, CA 91125 ung@caltech.edu (818)395-4901 (office) (818)395-4154 (lab) (818)796-7066 (fax) From owner-chromosomes@net.bio.net Mon Mar 11 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!gatech!newsfeed.internetmci.com!news.sprintlink.net!news.nis.net!slip-ppp5.paramus.nis.net!sengelke From: sengelke@nycradio.com (Stuart engelke) Newsgroups: bionet.genome.chromosomes Subject: Chromosome 17 Date: Tue, 12 Mar 1996 15:06:21 UNDEFINED Organization: National Internet Source, Inc. Lines: 4 Message-ID: NNTP-Posting-Host: slip-ppp5.paramus.nis.net Summary: want info Keywords: newborn X-Newsreader: Trumpet for Windows [Version 1.0 Rev B] I am considering adoption of a little girl that "had her #17 chromosome flip". The doctors do not know if any of the chromosome "broke off" or not. I am wondering what implications this may have to her future health.The doctors tell me she passes all her 6 month milestones now. From owner-chromosomes@net.bio.net Mon Mar 11 22:00:00 1996 Path: biosci!rutgers!gatech!newsfeed.internetmci.com!in2.uu.net!brighton.openmarket.com!decwrl!lll-winken.llnl.gov!fnnews.fnal.gov!nntp-server.caltech.edu!news From: "Dr. Ung-Jin Kim" Newsgroups: bionet.genome.chromosomes Subject: Caltech: lab assistants and a bioinformatician Date: Mon, 11 Mar 1996 17:20:11 -0800 Organization: California Institute of Technology Lines: 51 Message-ID: <3144D14B.3558@ash.tree.caltech.edu> NNTP-Posting-Host: apple.tree.caltech.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.4 sun4m) Genome Research Laboratory at Caltech: Please see our WEB page, http://www.tree.caltech.edu Job 1: We are looking for a few lab assistants ------- Caltech Genome Resaerch Laboratory is looking for qualified full time technicians with at least 1 year experience in laboratory works involving recombinant DNA procedures. Works will require skills in colony hybridization, PCR screening of genomic libraries, DNA preparation, restriction fingerprint analysis, and more. Positions are open immediately. A college degree in Biological sciences or other sciences required. Interested parties should send and salary requirement to Dr. Ung-Jin Kim. Electronic submissions are welcome. Job 2: We are looking for a bioinformatician ------- Caltech Genome Research Laboratory is looking for a full time informatician to manage and analyze laboratory data, and help operate robotic workstations. Knowledge and experieince in handling biological information, especially in the analysis and management of physcal mapping and DNA sequence data is essential. We also expect the person to be familiar with Unix server/workstations and PC/MacIntosh platforms. Interested parties should send CV and salary history to Dr. Ung-Jin Kim. Electronic submissions are welcome. We will notify the applicants if an interview is necessary soon after reviewing their applications. Caltech provides employees with excellent work environment and benefit plans. Ung-Jin Kim, Ph.D. 147-75, Division of Biology, Caltech, Pasadena, CA 91125 ung@caltech.edu (818)395-4901 (office) (818)395-4154 (lab) (818)796-7066 (fax) From owner-chromosomes@net.bio.net Wed Mar 13 22:00:00 1996 Path: biosci!rutgers!gatech!newsfeed.internetmci.com!sgigate.sgi.com!nntp.coast.net!swidir.switch.ch!scsing.switch.ch!elna.ethz.ch!usenet From: Alexander Kraev Newsgroups: bionet.genome.chromosomes Subject: Re: Primers for PCR? (Dog genomic) Date: 14 Mar 1996 18:12:38 GMT Organization: ETH Zentrum Zurich, Switzerland Lines: 25 Message-ID: <4i9nim$3k8@elna.ethz.ch> References: <4hp0hm$l5f@ratatosk.uio.no> NNTP-Posting-Host: bcmac6.ethz.ch Mime-Version: 1.0 Content-Type: multipart/mixed; boundary="-------------------------------320131692358" X-Mailer: Mozilla 1.1N (Macintosh; I; PPC) X-URL: news:4hp0hm$l5f@ratatosk.uio.no This is a multi-part message in MIME format. ---------------------------------320131692358 Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=us-ascii Hi there, Dog sodium-calcium exchanger gene NCX1 happens to have two very large exons, so that the primers can be inferred from the cDNA sequence. Accession M36119 contains the coding sequence, bases from 11 to 1840 can be used for PCR from genomic DNA, since this is an exon. Good luck, ---------------------------------320131692358 Content-Transfer-Encoding: 7bit Content-Type: text/plain Alexander Kraev, PhD Internet: kraev@bc.biol.ethz.ch > Lab.of Biochemistry III Phone: 0041-1-632-31-47 > Swiss Federal Inst. Of Technology FAX: 0041-1-632-12-13 > Universitaetsstr. 16 Home Page: http://www.bc.biol.ethz.ch/BiochemistryIII/ > CH-8092 Zurich /Sasha/kraev.html ---------------------------------320131692358-- From owner-chromosomes@net.bio.net Wed Mar 13 22:00:00 1996 Path: biosci!rutgers!gatech!news.jsums.edu!news2.cais.net!news.cais.net!news.ac.net!imci4!newsfeed.internetmci.com!in2.uu.net!news.accessone.com!not-for-mail From: rivero@accessone.com (Michael Rivero) Newsgroups: bionet.genome.chromosomes Subject: Question about eye color. Date: 14 Mar 1996 06:51:28 -0800 Organization: Accessone Lines: 14 Message-ID: <4i9bpg$fv0@pulm1.accessone.com> NNTP-Posting-Host: pulm1.accessone.com There doesn't seem to be a newsgroup specific to questions of heredity. What is the likelyhood that two blued parents will produce a brown eyed child? Thanks. -- ============== P I X E L O D E O N P R O D U C T I O N S ============== | Mike & Claire - The Rancho Runnamukka http://www.accessone.com/~rivero | =========================================================================== From owner-chromosomes@net.bio.net Thu Mar 14 22:00:00 1996 Path: biosci!daresbury!bioftp.unibas.ch!infobiogen.fr!jussieu.fr!oleane!tank.news.pipex.net!pipex!usenet.eel.ufl.edu!gatech!newsfeed.internetmci.com!hookup!news.nstn.ca!news.dal.ca!news From: "A. WILSON" Newsgroups: bionet.genome.chromosomes Subject: Re: Question about eye color. Date: 15 Mar 1996 13:20:33 GMT Organization: Nova Scotia Agricultural College Lines: 10 Message-ID: <4ibqr1$ojd@News.Dal.Ca> References: <4i9bpg$fv0@pulm1.accessone.com> NNTP-Posting-Host: cox-23-7b.nsac.ns.ca Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; I; 16bit) To: rivero@accessone.com The chances of two blue-eyed parents producing a brown-eyed child is about one in many many million. Brown eyes are dominant to blue. The only way this could happen could be through mutation (very rare). --------------------------------- |A microbiologist is someone who| |won't say that a restaurant was| | good for at least 24 hours. | --------------------------------- From owner-chromosomes@net.bio.net Thu Mar 14 22:00:00 1996 Path: biosci!daresbury!nntp-trd.UNINETT.no!newsfeed.sunet.se!news00.sunet.se!sunic!mn6.swip.net!plug.news.pipex.net!pipex!tank.news.pipex.net!pipex!newsfeed.internetmci.com!gatech!rutgers!csn!news-1.csn.net!csn!nntp-xfer-2.csn.net!tali.UCHSC.edu!essex.UCHSC.edu!binstoct From: Teresa Binstock Newsgroups: bionet.molbio.yeast,bionet.molbio.proteins,bionet.molbio.evolution,bionet.genome.chromosomes,bionet.general Subject: DATA BASE?: STE2 & STE3: yeast & humans. Date: Thu, 14 Mar 1996 18:08:09 -0700 Organization: University of Colorado, Health Sciences Center Lines: 39 Message-ID: References: NNTP-Posting-Host: essex.uchsc.edu Mime-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII In-Reply-To: Xref: biosci bionet.molbio.yeast:4953 bionet.molbio.proteins:7346 bionet.molbio.evolution:4329 bionet.genome.chromosomes:1073 bionet.general:20426 On Thu, 14 Mar 1996, Teresa Binstock wrote: > QUESTION about data base, if any: > > In one study findable via OVID search of Medline, STE2 and STE3 are > described as occurring in the human thymic epithelium. Otherwise, all the > other STE2 and STE3 studies refer to cell-surface receptors occurring in > Saccharomyces Cerevisiae. Many S. Cerevisiae genes and molecules have > homologues in mammals including humans. In fact, some human molecules > function in yeast and vice versa. > I would like to "pin-down" whether or not the human STE2 and STE3 > molecules reported by Patel et al are homologous to S. Cerevisiae > molecules with the same nomenclature. > Are there data bases other than Medline that would yield such > information? > > I would be very appreciative of being informed about such data bases and > how to access them. E-mails directly to me would be appreciated and/or to > the newsgroups if such distribution is appropriate. > > > > au: Patel et al > so: Journal of Clinical Immunology 15.2.80-92 1995 > ti: Characterization of human thymic epithelial cell surface antigens: > phenotypic similarity of thymic epithelial cells to epidermal > keratinocytes. > > > Thank you, > > > Teresa > > > Teresa C. Binstock, Researcher > Developmental & Behavioral Neuroanatomy > Denver CO USA > Teresa.Binstock@uchsc.edu From owner-chromosomes@net.bio.net Thu Mar 14 22:00:00 1996 Path: biosci!MENDEL.LLNL.GOV!greg From: greg@MENDEL.LLNL.GOV Newsgroups: bionet.genome.chromosomes Subject: Re: Question about eye color Date: 15 Mar 1996 12:47:30 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 40 Sender: daemon@net.bio.net Distribution: world Message-ID: <9603152044.AA01035@mendel.llnl.gov> NNTP-Posting-Host: net.bio.net This is incorrect. As stated in OMIM, "eye color is likely to be a polygenic trait. The early view that blue is a simple recessive has been repeatedly shown to be wrong by observation of brown-eyed offspring of 2 blue-eyed parents." To access the OMIM (Online Mendelian Inheritance in Man) database through the WWW, go to either the current URL: http://www3.ncbi.nlm.nih.gov/Omim/ or to the now historic URL: http://gdbwww.gdb.org/gdb-bin/omim/bin/omimq Greg Lennon Lawrence Livermore National Laboratory > From BIOSCI-REQUEST@net.bio.net Fri Mar 15 06:11:15 1996 > To: biochrom@net.bio.net > From: "A. WILSON" > Subject: Re: Question about eye color. > Date: 15 Mar 1996 13:20:33 GMT > Nntp-Posting-Host: cox-23-7b.nsac.ns.ca > Mime-Version: 1.0 > Content-Type> : > text/plain> ; > charset=us-ascii> > Content-Transfer-Encoding: 7bit > X-Mailer: Mozilla 1.22 (Windows; I; 16bit) > To: rivero@accessone.com > Content-Length: 465 > > The chances of two blue-eyed parents producing a brown-eyed child is > about one in many many million. Brown eyes are dominant to blue. The > only way this could happen could be through mutation (very rare). > > --------------------------------- > |A microbiologist is someone who| > |won't say that a restaurant was| > | good for at least 24 hours. | > --------------------------------- > > > From owner-chromosomes@net.bio.net Fri Mar 15 22:00:00 1996 Path: biosci!AIX1.UOTTAWA.CA!s060965 From: s060965@AIX1.UOTTAWA.CA Newsgroups: bionet.genome.chromosomes Subject: Re: methylation of DNA in mice Date: 16 Mar 1996 06:08:21 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 35 Sender: daemon@net.bio.net Distribution: world Message-ID: References: NNTP-Posting-Host: net.bio.net Expensive?????? Relative to what??? I've been using HpaII and MspI for years and doing similar experiments. I suspect it is one of the cheaper pairs. Certainly it is more expensive than things like BamHI or EcoRI .... but not much .... compare it to the price of Taq polymerase or some of the other stranger restriction enzymes. And considering that almost everyone using these two enzymes for methylation studies, it probably would be unwise to alter from this. Cris Martin On 15 Mar 1996 mrtour@stud.med.cornell.edu wrote: > I want to examine DNA methylation differences in two types of mice....i > plan to do this by utilizing 2 restriction enzymes which are isoschizomers > (recognize the same cut site) but one is sensitive to methylation at the > site and the other isn't... > > one pair of which i am absolute sure of is MspI and HpaII...but these are > expensive....would anyone know of another pair which would do the same > thing but perhaps be cheaper? > > thank you for your help. > > please post here or to mrtour@stud.med.cornell.edu > > michelle > > -- > db > > or Michelle > > From owner-chromosomes@net.bio.net Fri Mar 15 22:00:00 1996 Path: biosci!CS.Arizona.EDU!noao!ennfs.eas.asu.edu!gatech!newsfeed.internetmci.com!howland.reston.ans.net!vixen.cso.uiuc.edu!uwm.edu!msunews!netnews.upenn.edu!sanger.bcm.tju.edu!tromp From: tromp@sanger.bcm.tju.edu (Gerard Tromp) Newsgroups: bionet.genome.chromosomes Subject: Re: Question about eye color. Date: 15 Mar 1996 19:48:34 GMT Organization: Biochemistry Lines: 24 Distribution: world Message-ID: <4ichii$qli@netnews.upenn.edu> References: <4i9bpg$fv0@pulm1.accessone.com> <4ibqr1$ojd@News.Dal.Ca> NNTP-Posting-Host: sanger.bcm.tju.edu In article <4ibqr1$ojd@News.Dal.Ca>, "A. WILSON" writes: > The chances of two blue-eyed parents producing a brown-eyed child is > about one in many many million. Brown eyes are dominant to blue. The > only way this could happen could be through mutation (very rare). > Patently false. Assumes that eye color is inherited as a simple single-locus mendelian trait, it is not. Also, in some simple single-locus mendelian traits which are caused predominantly by de novo mutations, the mutation rate can be much higher, in the range of 1 in 10 or 20 thousand. Simply put, it is not possible to give and estimate without considerable additional information (data). Gerard Tromp -- ======================================================================= Gerard Tromp, Ph.D. Assistant Professor Vox: 313-577-8773 Center for Molecular Medicine and Genetics Fax: 313-577-5218 Wayne State University 540 East Canfield Ave., Room 3116 E-mail: tromp@sanger.med.wayne.edu Detroit, MI 48201 gtromp@cmb.biosci.wayne.edu U.S.A. From owner-chromosomes@net.bio.net Fri Mar 15 22:00:00 1996 Path: biosci!rutgers!csn!news-1.csn.net!magnus.acs.ohio-state.edu!lerc.nasa.gov!purdue!haven.umd.edu!hecate.umd.edu!research-01.ski.mskcc.org!ski-h-99-094.ski.mskcc.org!user From: mrtour@stud.med.cornell.edu,dburtrum@ski.mskcc.org (michelle or doug......) Newsgroups: bionet.molbio.methds-reagnts,bionet.genome.chromosomes, Subject: methylation of DNA in mice Date: 15 Mar 1996 22:33:25 GMT Organization: Memorial Sloan-Kettering Cancer Center Lines: 19 Message-ID: NNTP-Posting-Host: ski-h-99-094.ski.mskcc.org Xref: biosci bionet.molbio.methds-reagnts:41917 bionet.genome.chromosomes:1077 I want to examine DNA methylation differences in two types of mice....i plan to do this by utilizing 2 restriction enzymes which are isoschizomers (recognize the same cut site) but one is sensitive to methylation at the site and the other isn't... one pair of which i am absolute sure of is MspI and HpaII...but these are expensive....would anyone know of another pair which would do the same thing but perhaps be cheaper? thank you for your help. please post here or to mrtour@stud.med.cornell.edu michelle -- db or Michelle From owner-chromosomes@net.bio.net Sat Mar 16 22:00:00 1996 Path: biosci!ns1.faseb.org!lamarck.sura.net!newsfeed.internetmci.com!howland.reston.ans.net!newsjunkie.ans.net!newsfeeds.ans.net!news.rmii.com!estreet.com!user From: kcollins@estreet.com (Kent F. Collins) Newsgroups: bionet.genome.chromosomes Subject: HELP< HELP Date: Sat, 16 Mar 96 16:24:09 -0700 Organization: E Street Denver Lines: 5 Message-ID: <4949566.ensmtp@estreet.com> NNTP-Posting-Host: news.estreet.com X-Newsreader: ExpressNet/SMTP v1.1.5 I need some clip art of cell miosis, mitosis and fertilization of 2 haploid cells. Thanks E-mail to kcollins@estreet.com From owner-chromosomes@net.bio.net Sat Mar 16 22:00:00 1996 Path: biosci!UCRAC1.UCR.EDU!judelson From: judelson@UCRAC1.UCR.EDU (Howard S. Judelson) Newsgroups: bionet.genome.chromosomes Subject: postdoc positions: fungal genetics/map-based cloning/gene analysis Date: 17 Mar 1996 14:23:05 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 43 Sender: daemon@net.bio.net Distribution: world Message-ID: <199603172220.OAA07602@click.ucr.edu> NNTP-Posting-Host: net.bio.net POSTDOCTORAL POSITIONS Molecular genetics of the oomycete fungus, Phytophthora infestans Candidates are sought for two postdoctoral positions in a laboratory investing the molecular genetics of Phytophthora infestans, an oomycete fungus that causes the important late blight diseases of potato and tomato. Successful applicants can join either of several on-going projects. These include the positional cloning of genes determining mating type (sexual compatibility type; see Judelson et al. 1995, Genetics 141:503-512); the analysis of genome rearrangements associated with a system of balanced lethals in Phytophthora; the characterization of mating-induced genes (isolated by differential display and subtraction cloning); and the analysis of genes determining resistance to fungicides. Major funding for these positions comes from grants from the USDA and NSF. Applicants should have a Ph.D. and some experience in molecular biology. Depending on the project, the experiments will involve techniques such as genetic mapping, long-range restriction mapping, chromosome walking in cosmid and BAC libraries, and fungal transformation; experience with these would be helpful but is not required. Please sent a curriculum vitae and the names of three references (including addresses and telephone numbers) to: Howard Judelson Department of Plant Pathology University of California Riverside, California 92521 USA email: judelson@ucrac1.ucr.edu fax: 909-787-4294 Howard Judelson (judelson@ucrac1.ucr.edu) Assistant Professor Department of Plant Pathology University of California Riverside, California 92521 USA Tel: 909-787-4199 Fax: 909-787-4294 From owner-chromosomes@net.bio.net Sun Mar 17 22:00:00 1996 Path: biosci!rutgers!uwm.edu!cs.utexas.edu!howland.reston.ans.net!newsfeed.internetmci.com!in1.uu.net!news.epix.net!usenet From: wild@epix.net (Wild Dude) Newsgroups: bionet.genome.chromosomes Subject: a biology students wants your help Date: Mon, 18 Mar 1996 00:35:23 GMT Organization: epix.net Lines: 16 Message-ID: <4iib1m$egf@guava.epix.net> NNTP-Posting-Host: lsptppp68.epix.net X-Newsreader: Forte Free Agent 1.0.82 Dear scientists, I'm a 16 year old high school biology student. In class, we are studying genetics, and your project came up in discussion. I admire your work, and wish you well in it. My teacher said, jokingly, that she'd give an "A" to anyone who could put together a Punnett Square for a human being, showing all chromosomes and possible crosses. I know that creating a Punnett Square of this size would be impossible to do with a pencil and paper, but I thought that there might be a way to do it with a computer. I'd really like to do this, just to see what my teacher says about it. Please respond to me by email at WILD@EPIX.NET . Thank you VERY much for your valuable time. Sincerely, Brian Snyder wild@epix.net From owner-chromosomes@net.bio.net Sun Mar 17 22:00:00 1996 Path: biosci!daresbury!bioftp.unibas.ch!infobiogen.fr!jussieu.fr!oleane!tank.news.pipex.net!pipex!swrinde!howland.reston.ans.net!nntp.coast.net!swidir.switch.ch!scsing.switch.ch!elna.ethz.ch!smac.ethz.ch!user From: tan@mol.biol.ethz.ch (Song Tan) Newsgroups: bionet.molbio.yeast,bionet.molbio.proteins,bionet.molbio.evolution,bionet.genome.chromosomes,bionet.general Subject: Re: DATA BASE?: STE2 & STE3: yeast & humans. Date: Mon, 18 Mar 1996 16:38:54 +0100 Organization: ETH-Honggerberg (Swiss Federal Institute of Technology) Lines: 43 Message-ID: References: NNTP-Posting-Host: smac.ethz.ch Xref: biosci bionet.molbio.yeast:4969 bionet.molbio.proteins:7367 bionet.molbio.evolution:4345 bionet.genome.chromosomes:1082 bionet.general:20514 In article , Teresa Binstock wrote: > On Thu, 14 Mar 1996, Teresa Binstock wrote: > > > QUESTION about data base, if any: > > > > In one study findable via OVID search of Medline, STE2 and STE3 are > > described as occurring in the human thymic epithelium. Otherwise, all the > > other STE2 and STE3 studies refer to cell-surface receptors occurring in > > Saccharomyces Cerevisiae. Many S. Cerevisiae genes and molecules have > > homologues in mammals including humans. In fact, some human molecules > > function in yeast and vice versa. > > I would like to "pin-down" whether or not the human STE2 and STE3 > > molecules reported by Patel et al are homologous to S. Cerevisiae > > molecules with the same nomenclature. > > > > au: Patel et al > > so: Journal of Clinical Immunology 15.2.80-92 1995 > > ti: Characterization of human thymic epithelial cell surface antigens: > > phenotypic similarity of thymic epithelial cells to epidermal > > keratinocytes. I find Entrez to be the best tool for tracking down sequences. However, I didn't find any non-yeast STE2 or STE3 sequences in the GenBank database that Entrez uses, nor any relevant epithelial sequences from authors named Patel. Since I don't have access to the article you cited, I wasn't able to figure out if the authors published the sequences of the human STE2 and STE3 genes. If they did, it would be easy to compare them against the yeast STE2 and STE3 genes. If they didn't publish any sequence, I'm not sure you will find any other publicly available databases that might answer whether the human and yeast genes are related. Hope this helps. -- Song Tan Institute for Molecular Biology and Biophysics ETH-Honggerberg (Swiss Federal Institute of Technology) 8093 Zurich, Switzerland email: tan@mol.bio.ethz.ch From owner-chromosomes@net.bio.net Sun Mar 17 22:00:00 1996 Path: biosci!lhc.nlm.nih.gov!borduas!francis From: francis@borduas.nlm.nih.gov (Francis Ouellette) Newsgroups: bionet.molbio.yeast,bionet.molbio.proteins,bionet.molbio.evolution,bionet.genome.chromosomes,bionet.general Subject: Re: DATA BASE?: STE2 & STE3: yeast & humans. Followup-To: bionet.molbio.yeast,bionet.molbio.proteins,bionet.molbio.evolution,bionet.genome.chromosomes,bionet.general Date: 18 Mar 1996 22:06:52 GMT Organization: National Library of Medicine Lines: 18 Message-ID: <4ikmps$lkg@lhc.nlm.nih.gov> References: NNTP-Posting-Host: 130.14.25.167 X-Newsreader: TIN [version 1.2 PL2] Xref: biosci bionet.molbio.yeast:4971 bionet.molbio.proteins:7372 bionet.molbio.evolution:4348 bionet.genome.chromosomes:1083 bionet.general:20525 Song Tan (tan@mol.biol.ethz.ch) wrote: > I find Entrez to be the the proper URL for Entrez is: http://www3.ncbi.nlm.nih.gov/Entrez/ regards, francis -- | B.F. Francis Ouellette | GenBank | | francis@ncbi.nlm.nih.gov From owner-chromosomes@net.bio.net Mon Mar 18 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!newsfeed.internetmci.com!in2.uu.net!fdn.fr!r2d2.fdn.org!med.univ-tours.fr!news.univ-angers.fr!jussieu.fr!univ-lyon1.fr!news From: 4BC Newsgroups: bionet.genome.chromosomes Subject: help RETROTRANSPOSONS Date: 19 Mar 1996 18:38:26 GMT Organization: insa-lyon.fr Lines: 7 Message-ID: <4imuv2$g74@tempo.univ-lyon1.fr> NNTP-Posting-Host: pc406-07.insa-lyon.fr Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; I; 16bit) Sorry I sent an article named "re : retrotransposon" but I made a mistake I'm actually looking for synthetic easy to understand paper or book on this topic Thanks to email me Eric From owner-chromosomes@net.bio.net Mon Mar 18 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!newsfeed.internetmci.com!in2.uu.net!fdn.fr!med.univ-tours.fr!news.univ-angers.fr!jussieu.fr!univ-lyon1.fr!news From: 4BC Newsgroups: bionet.genome.chromosomes Subject: RE : retrotransposon Date: 19 Mar 1996 18:31:01 GMT Organization: insa-lyon.fr Lines: 9 Message-ID: <4imuh5$g74@tempo.univ-lyon1.fr> NNTP-Posting-Host: pc406-07.insa-lyon.fr Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; I; 16bit) I'm a student in biochemistry and I have to work on retrotransposon to make a presentation in my course of genetic of microorganisms. If you know a good,easy to understand reference on this topic could you please email me. I'm looking for synthetic book or paper thank you in advance Eric From owner-chromosomes@net.bio.net Mon Mar 18 22:00:00 1996 Path: biosci!ns1.faseb.org!lamarck.sura.net!newsfeed.internetmci.com!tank.news.pipex.net!pipex!lade.news.pipex.net!pipex!bbc!news From: KathyBarnby Newsgroups: bionet.genome.chromosomes Subject: BBC TV Natural History of Human Body Date: 19 Mar 1996 12:25:28 GMT Organization: BBC Lines: 26 Message-ID: <4im93o$22c@bbcnews.rd.bbc.co.uk> NNTP-Posting-Host: 132.185.52.216 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; I; 16bit) BBC Needs Help With Natural History of Human Body The BBC are making a series of programmes about the Human Body. They will illustrate what science can currently tell us about how the human body works and how it evolved. If you have research that you think would help us to visualise human biological processes in a new and enlightening way, please contact me at kathy.barnby@bbc.co.uk *+44.181.752.6210 and fax +44.181.752 6810 in London. I would love to see examples of images created by new technologies such as magnetic resonance imaging, ultrasound, computer analysis of X-ray and PET scans. Also film or video images, no matter how old, which show the processes of our bodies. We want to illustrate human life from conception, through foetal development, into babyhood, childhood, before and after puberty, the ageing process, death and beyond. Examples of the moments we might capture on film are: 1 Meiosis 2 SEM images of chromosomes 3 how small can you go? From owner-chromosomes@net.bio.net Mon Mar 18 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!in2.uu.net!fdn.fr!r2d2.fdn.org!med.univ-tours.fr!news.univ-angers.fr!jussieu.fr!univ-lyon1.fr!news From: 4eme annee biochimie Newsgroups: bionet.genome.chromosomes Subject: heterologous expression Date: 19 Mar 1996 19:14:09 GMT Organization: Biochimie Lines: 9 Message-ID: <4in121$j8k@tempo.univ-lyon1.fr> NNTP-Posting-Host: pc406-08.insa-lyon.fr Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; I; 16bit) hi! I'm student in national institut of applied science of lyon (France), in biochemistry department. I have to work on heterologous expression for my course of molecular genetic. I'm looking for documents about it. It would be very nice of you if you email me some informations. Thank you Nico. From owner-chromosomes@net.bio.net Mon Mar 18 22:00:00 1996 Path: biosci!CGNET.COM!A.VALLADOLID From: A.VALLADOLID@CGNET.COM ("Valladolid, Andres") Newsgroups: bionet.genome.chromosomes Subject: (none) Date: 19 Mar 1996 14:22:22 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 2 Sender: daemon@net.bio.net Distribution: world Message-ID: <314F325D@msm.cgnet.com> NNTP-Posting-Host: net.bio.net subscribe chromosomes From owner-chromosomes@net.bio.net Tue Mar 19 22:00:00 1996 Path: biosci!rutgers!gatech!newsfeed.internetmci.com!hookup!news.nstn.ca!coranto.ucs.mun.ca!leif!pallderdice From: pallderdice@kean.ucs.mun.ca Newsgroups: bionet.genome.chromosomes Subject: Is there anyone who has two translocation chromosomes from #21 & #22? Date: 19 Mar 96 21:07:14 -0330 Organization: Memorial University. St.John's Nfld, Canada Lines: 19 Message-ID: <1996Mar19.210714.1@leif> NNTP-Posting-Host: leif.ucs.mun.ca I know a mother and daughter who are physically and mentally normal and each has two translocation chromosomes. One includes the long arm of chromosome 21 and the long arm of chromosome 22. The second is formed by the short arm of chromosome 21 and the short arm of chromosome 22. I am writing the karytoype: 46,XX,-21,-22,+t(21q22q),+t(21p22p). The mother had a normal daughter, and then repeated apontaneous abortions. The daughter had a spontaneous abortion, with a karyotype like the mothers' .Her next pregnancy was a Down syndrome (trisomy 21). The chromosomes for the Down syndrome were the same as the mothers' plus another chromosome 21. The daughter would like to correspond with someone else who has the same balanced chromosome rearrangement as her own. Specifically, she would like to hear that this unknown person, has had some normal liveborn infants. Thank you, Penny From owner-chromosomes@net.bio.net Tue Mar 19 22:00:00 1996 Path: biosci!agate!howland.reston.ans.net!newsfeed.internetmci.com!uwm.edu!news.inap.net!news From: Nick Golas Newsgroups: bionet.genome.chromosomes Subject: Smith's Lemli Opitz Syndrome Date: 20 Mar 1996 10:44:09 GMT Organization: NAP.NET -- Milwaukee, WI Lines: 3 Message-ID: <4ionhp$2ct@news.inap.net> NNTP-Posting-Host: 207.7.32.115 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; U; 16bit) To: ALl My friend's little boy has this (he's 14). Are there any other parents who have children diagnosed with SLO out there? From owner-chromosomes@net.bio.net Tue Mar 19 22:00:00 1996 Path: biosci!agate!howland.reston.ans.net!news.moneng.mei.com!uwm.edu!news.inap.net!news From: Nick Golas Newsgroups: bionet.genome.chromosomes Subject: Smith's Lemli Opitz Syndrome Date: 20 Mar 1996 10:44:46 GMT Organization: NAP.NET -- Milwaukee, WI Lines: 24 Message-ID: <4ioniu$2ct@news.inap.net> NNTP-Posting-Host: 207.7.32.115 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.22 (Windows; U; 16bit) To: ALl My friend's little boy has this (he's 14). Are there any other parents who have children diagnosed with SLO out the> > -------------------------------------------------------------------- > > Newsgroup: bionet.genome.chromosomes > > * HELP< HELP - Kent F. Collins (5) > * postdoc positions: fungal genetics/map-based cloning/gene > analysis - Howard S. Judelson (43) > * a biology students wants your help - Wild Dude (16) > * Re: DATA BASE?: STE2 & STE3: yeast & humans. - Song Tan (43) > o Francis Ouellette (18) > * BBC TV Natural History of Human Body - KathyBarnby (26) > * RE : retrotransposon - 4BC (9) > * help RETROTRANSPOSONS - 4BC (7) > * heterologous expression - 4eme annee biochimie (9) > * (none) - "Valladolid, Andres" (2) > * Is there anyone who has two translocation chromosomes from #21 > & #22? - pallderdice@kean.ucs.mun.ca (19) > > -------------------------------------------------------------------- > re? From owner-chromosomes@net.bio.net Wed Mar 20 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!in2.uu.net!newsfeed.pitt.edu!news From: jcard+@pitt.edu (John J. Cardamone Jr.) Newsgroups: bionet.genome.chromosomes Subject: Used Dupont Genesis DNA Sequencers FOR SALE Date: 21 Mar 1996 20:31:18 GMT Organization: University of Pittsburgh Lines: 10 Sender: jcard@pop.pitt.edu Message-ID: <4iseam$hef@usenet.srv.cis.pitt.edu> NNTP-Posting-Host: quad840av.mgen.pitt.edu X-Posted-From: InterNews 1.0.1b23@quad840av.mgen.pitt.edu X-Authenticated: jcard on POP host pop.pitt.edu University of Pittsburgh, Dept. of Molecular Genetics & Biochemistry, Research Support Facilities. We have 2 Genesis Automated DNA sequencers in good condition. Please contact John Cardamone 412-383-9769 jcard+@pitt.edu From owner-chromosomes@net.bio.net Wed Mar 20 22:00:00 1996 Newsgroups: bionet.genome.chromosomes Path: biosci!ns1.faseb.org!lamarck.sura.net!fconvx.ncifcrf.gov!tobin From: tobin@ncifcrf.gov (Greg Tobin) Subject: in situ hybridization Message-ID: Organization: Frederick Cancer Research and Development Center Date: Thu, 21 Mar 1996 18:24:43 GMT Lines: 16 Our lab is getting into in situ hybridization to identify tissues containing specific DNA or RNA. This would entail standard in situ hybridization, PCR in situ, and RT-PCR in situ. There are many, many protocols out there for doing these experiments. At first, I would like to try in situ hyb with a radioactive probe and then move to a fluorescent probe. The PCR-based assays would be fluorescent. Can I get some opinions on how to make the best probe? How long should it be for in situ hyb? Would a random primed or PCR-generated probe have higher sp. activity than the nick-translation probes? If the target is 2.5 kb, would it be better to use a 2.5 kb probe or an 0.5 kb probe (the smaller probe might penetrate and bind better). Any advice would be appreciated. From owner-chromosomes@net.bio.net Wed Mar 20 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!tank.news.pipex.net!pipex!oleane!jussieu.fr!univ-compiegne.fr!u-picardie.fr!usenet From: ghislaine.grenier@isab.fr Newsgroups: bionet.genome.chromosomes Subject: Lipid Transfer Protein cDNAs Date: Thu, 21 Mar 1996 18:23:36 GMT Organization: Universite de Picardie-Jules Verne - Amiens - France Lines: 9 Distribution: inet Message-ID: <4ir7gs$phv@gip.u-picardie.fr> NNTP-Posting-Host: pc3.isab.fr X-Newsreader: Forte Free Agent 1.0.82 I'd like to know if there is a data base about LTP cDNAs. I would be very appreciative of being informed about such data bases and how to access them. E-mails directly to me would be appreciated and/or to the newsgroups if such distribution is appropriate. E-mail : ghislaine.grenier@isab.fr From owner-chromosomes@net.bio.net Wed Mar 20 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!in2.uu.net!newsfeed.pitt.edu!news From: jcard+@pitt.edu (John J. Cardamone Jr.) Newsgroups: bionet.genome.chromosomes Subject: University of Pittsburgh, Dept. of Molecular Genetics & Biochemistry's New Home Page Date: 21 Mar 1996 20:32:03 GMT Organization: University of Pittsburgh Lines: 5 Sender: jcard@pop.pitt.edu Message-ID: <4isec3$heg@usenet.srv.cis.pitt.edu> References: <4gddtm$grq@usenet.srv.cis.pitt.edu> NNTP-Posting-Host: quad840av.mgen.pitt.edu X-Posted-From: InterNews 1.0.1b23@quad840av.mgen.pitt.edu X-Authenticated: jcard on POP host pop.pitt.edu Please visit our new Home Page http://www.pitt.edu/~rsup/mgb From owner-chromosomes@net.bio.net Wed Mar 20 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!in2.uu.net!newsfeed.pitt.edu!news From: jcard+@pitt.edu (John J. Cardamone Jr.) Newsgroups: bionet.genome.chromosomes Subject: University of Pittsburgh, Dept. of Molecular Genetics & Biochemistry's New Home Page Date: 21 Mar 1996 20:32:23 GMT Organization: University of Pittsburgh Lines: 5 Sender: jcard@pop.pitt.edu Message-ID: <4isecn$hgq@usenet.srv.cis.pitt.edu> References: <4gddtm$grq@usenet.srv.cis.pitt.edu> NNTP-Posting-Host: quad840av.mgen.pitt.edu X-Posted-From: InterNews 1.0.1b23@quad840av.mgen.pitt.edu X-Authenticated: jcard on POP host pop.pitt.edu Please visit our new Home Page http://www.pitt.edu/~rsup/mgb From owner-chromosomes@net.bio.net Thu Mar 21 22:00:00 1996 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!chi-news.cic.net!news.compuserve.com!news.production.compuserve.com!news From: Mark Langan <100071.3213@CompuServe.COM> Newsgroups: bionet.genome.chromosomes Subject: Chromosomes 7 & 8. Translocation Pr Date: 22 Mar 1996 19:17:48 GMT Organization: CompuServe, Inc. (1-800-689-0736) Lines: 13 Message-ID: <4iuucs$h2$1@mhafc.production.compuserve.com> I am not sure I have the right newsgroup. I am looking for information on an unbalanced translocation of chromosomes 7 and 8. It has caused a physical development to slow in the body of a male 2 year old child. The head is growing normally and is as it should be. I would appreciate any information on, or treatments for this condition or sources of information etc. TIA Mark Langan From owner-chromosomes@net.bio.net Fri Mar 22 22:00:00 1996 Path: biosci!biosci!not-for-mail From: white@pobox.upenn.edu (Peter White) Newsgroups: bionet.genome.chromosomes Subject: Human chromosome 1 WWW site Date: 22 Mar 1996 21:00:35 -0800 Organization: Children's Hospital of Philadelphia Lines: 25 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Human chromosome 1 WWW site Announcing the opening of a human chromosome 1 World Wide Web site. This resource is available on-line at: http://linkage.cpmc.columbia.edu/chr1/ The WWW site contains pertinent information regarding cytogenetic, genetic, physical, and transcript mapping exclusively of or including the largest human chromosome. Current resources include: -Repository of meeting information and report of the September 1995 chromosome 1 workshop -Directory of links to available chromosome 1-specific mapping information -On-line forum for discussion of chromosome 1 mapping and sequencing issues This resource is sponsored by a collaboration between the Statistical Genetics Group at Columbia University and the Division of Oncology at the Children's Hospital of Philadelphia, with guidance from much of the chromosome 1 mapping community. For further information, please contact Pete White at white@kermit.oncol.chop.edu or Tara Matise at tara.matise@columbia.edu. From owner-chromosomes@net.bio.net Tue Mar 26 22:00:00 1996 Message-ID: <190328Z26031996@anon.penet.fi> Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!usc!elroy.jpl.nasa.gov!swrinde!howland.reston.ans.net!EU.net!news.eunet.fi!anon.penet.fi Newsgroups: alt.drugs.pot.cultivation,alt.hemp,bionet.plants,bionet.genome.chromosomes,alt.sustainable.agriculture,rec.gardens,carleton.clubs.cannabis,sdnet.hemp From: an307269@anon.penet.fi (Alien Anthropologist) X-Anonymously-To: alt.drugs.pot.cultivation,,alt.hemp,bionet.plants,bionet.genome.chromosomes,alt.sustainable.agriculture,rec.gardens,carleton.clubs.cannabis,sdnet.hemp Organization: Anonymous forwarding service Reply-To: an307269@anon.penet.fi Date: Tue, 26 Mar 1996 18:57:40 UTC Subject: Re: (fwd) Botany of Skunk/Northern-Lights/Kush cross Lines: 20 Xref: biosci bionet.plants:10675 bionet.genome.chromosomes:1099 rec.gardens:103584 People with a moral problem with a plant, please read no further (get an education while you're at it) Cannabis: Last year AFOAF had the most amazing hybrid (what they say was a Northern Lights x Skunk hybrid. Unfortunately his/her last clone died, but not before s/he had a chance to cross with a Kush male. My questions stemming (no punn intended) purely from a curiosity standpoint, and a haphazard genetic education are as follows: 1) Why did the plant seem to remain with only 3 blades per leaf, long after reverting from flowering cycle - would it ever have changed back to 5? --****ATTENTION****--****ATTENTION****--****ATTENTION****--***ATTENTION*** Your e-mail reply to this message WILL be *automatically* ANONYMIZED. Please, report inappropriate use to abuse@anon.penet.fi For information (incl. non-anon reply) write to help@anon.penet.fi If you have any problems, address them to admin@anon.penet.fi From owner-chromosomes@net.bio.net Tue Mar 26 22:00:00 1996 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.genome.chromosomes Subject: IMPORTANT - BIOSCI Fundraising Update! Date: 27 Mar 1996 02:00:38 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 149 Sender: daemon@net.bio.net Distribution: world Message-ID: <199603271000.CAA20959@net.bio.net> NNTP-Posting-Host: net.bio.net I'm interrupting the usual monthly posting of the BIOSCI miniFAQ to bring you up to date on BIOSCI fundraising progress, a topic of concern to your future use of this resource. Thank you in advance for taking the time to read this message carefully. Last year we announced that BIOSCI was going to adopt the U.S. Public Broadcasting System model to fund its operations after our DOE/NSF grant runs out later this year. Unlike PBS, we are not soliciting contributions from users; we are only selling ads on our Web pages solely to cover our operating costs. Our goal is to seek sponsorships until we build up an operating reserve of about $100,000 and then cease further promotions until we need to build the reserve back up. (The accountants among our readership will be familiar with the problem of deferred revenue which we can not safely utilize until ads have been displayed for a period of time.) We have three sponsors to date with a couple more pending. The process is time-consuming, however, and we need your help as explained further below. Our operating costs consist of our network connection, phone lines, hardware maintenance (we hope to have new and faster hardware soon!), plus 0.7 FTE of salaries covering UNIX systems admin, technical support, quality assurance, i.e., testing, of our system, and administrative costs (such as the time it takes to actually find/write/call potential sponsors and raise money!). Although the BIOSCI staff does get compensated for a portion of the work that they do, this project has always received a lot of free after-hours and "vacation" time labor, so we hope that no one will begrudge the time that we do charge to the project to serve you. All of the three part-time staff members, Dave Mack, Julie Lawrence, and myself, have full time day jobs and families in addition to working hard to keep this service running for all of you. Julie and Dave Mack are subcontractors for BIOSCI; my time that is charged to the project defrays a portion of my regular salary instead of adding to my income. Besides having to relocate the project, we were very busy this last year building new infrastructure such as our WWW hypermail interface to the system. This was released last December along with scores of WAIS indices for the newsgroups. Virtually everything is complete, although we do continue to find and fix bugs (many through your helpful feedback!). We are still having some problems with our WAIS indexing. The archives continue to grow rapidly. We are running over 100 indexes now versus three previously and any systems crashes cause greater havoc with the indexing than before! We are still working to fix this as fast as our resources permit and appreciate your patience, but we have been able to automate a lot of the infrastructure to reduce labor as compared to past requirements. We have also implemented new software to make moderation of BIOSCI/bionet newsgroups much easier and combat the growing problem of Internet junk mail and USENET "spamming." About 20% of our groups are now moderated, many of them by the BIOSCI staff! This, for example, made a major difference last year in the quality of content in our EMPLOYMENT/bionet.jobs.offered newsgroup which many commercial concerns and recruiting firms are using **without charge** to recruit candidates for positions in the biological sciences. We are also now in a position to have sponsors for individual newsgroups as you will have noticed if you have visited http://www.bio.net/ and clicked on "Access the BIOSCI/bionet newsgroups" recently. So, how can you help?? ---------------------- As noted above it can take a lot of time to contact potential sponsors if I have to do it all myself. Our request is quite simple. You can do two important things which will take very little time for you individually. First, please use our WWW system at http://www.bio.net/ to access the archives. You can now post or reply to messages via your Web browser. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. Our hope is to quickly raise several large corporate/institutional sponsors on our heavily-used WWW locations (some stats appended below), and then end this sponsorship campaign so that our resources can continue to be used for service provision, not fundraising. Many of our specialty newsgroup WWW archives are still used by small communities of scientists (and they haven't been heavily promoted yet). While these may be valuable niche markets to some advertisers, it will generate more labor and overhead having to find these sponsors, fairly price the locations, and deal with lots of smaller sponsorships than fewer mid-to large sponsors. We are striving to keep our operation as lean and efficient as possible since we are not trying to make careers out of running BIOSCI. We are trying if at all possible to avoid the administrative overhead entailed with processing lots of small payments to reach our fundraising goals. I'd like to thank all of you for your help in advance. In helping us, you are also helping yourselves, not only in keeping this resource available for all of the both large and small research communities that we serve, but also by alleviating the need for us to go back and compete with researchers for tight grant dollars! We promised NSF when we were awarded the BIOSCI grant that we would carry out this mission to make the service self-supporting. With your help, we will succeed in continuing BIOSCI's work into its second decade. Thank you very much! Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net A list of our prime WWW sponsorship locations follow. Statistics are for the four week period from 22 Jan. - 18 Feb. 1996 and usage continues to grow. ---------------------------------------------------------------------- The overall BIOSCI WWW pages are currently visited by users from close to 5000 unique computer hosts per week. Web servers only log the Internet computer/host name and frequently more than one individual can connect to us from a particular host. Main home page, http://www.bio.net, visited recently by about 2100 unique hosts per week Main Newsgroups archives page, http://www.bio.net/archives.html, visited recently by about 1200 Unique hosts per week BIO-JOURNALS archive page, http://www.bio.net/BIO-JOURNALS.html, visited recently by about 1000 unique hosts per week. EMPLOYMENT archive pages: http://www.bio.net:80/hypermail/EMPLOYMENT/ and monthly header pages, visited recently by about 600 unique hosts per week. Address database search page, http://www.bio.net/addrsearch.html, visited recently by about 450 unique hosts per week. Methods newsgroup archive pages, http://www.bio.net:80/hypermail/METHDS- REAGNTS/ and monthly header pages, visited recently by about 350 unique hosts per week. ---------------------------------------------------------------------- From owner-chromosomes@net.bio.net Wed Mar 27 22:00:00 1996 Path: biosci!MAIL.MED.UPENN.EDU!dnaseq From: dnaseq@MAIL.MED.UPENN.EDU (Vahe Bedian) Newsgroups: bionet.genome.chromosomes Subject: Position at Penn Date: 28 Mar 1996 07:55:07 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 37 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net University of Pennsylvania Department of Genetics DNA Sequencing Facility 455 CRB, Philadelphia, PA 19104-6145 Phone: 573-7407 Fax: 573-9327 E-mail:dnaseq@mail.med.upenn.edu -------------------------------------------------------------------- Position Available: Research Specialist I or II The facility has two ABI 373 Stretch Automated Sequencers, one ABI 377 Automated Sequencer, and one ABI 394 Oligonucleotide Synthesizer. It provides template preparation, DNA sequencing, primer walking, GeneScan (fragment sizing), oligonucleotide synthesis, sequence assembly and analysis, and other molecular biological services. Applicants should have a B.S. in a biological field or equivalent; 1-2 years experience also required for Research Specialist I level, 2-3 years of experience for the Research Specialist II level. Previous experience in DNA sequencing, molecular biology, and computers desirable. Duties include: Prepare templates and samples for automated sequencing Pour & run DNA sequencing and GeneScan gels Operate ABI 373 and 377 sequencers with Sequencing and GeneScan software Synthesize oligonucleotides on the ABI 394 synthesizer Manage large sequencing projects Provide technical support and consultation to facility users Perform sequence analysis and computerized searches If interested send resume' to Dr. Vahe Bedian at the above address or fax resume' to 215-573-9327 Call 215-573-7407 or e-mail dnaseq@mail.med.upenn.edu for inquiries From owner-chromosomes@net.bio.net Thu Mar 28 22:00:00 1996 Path: biosci!rutgers!gatech!swrinde!newsfeed.internetmci.com!news.dacom.co.kr!nntp.coast.net!fu-berlin.de!rag2.rz-berlin.mpg.DE!leser From: Ulf Leser Newsgroups: bionet.genome.chromosomes Subject: An X chromosome YAC map Date: Fri, 29 Mar 1996 18:31:54 +0100 Organization: MPI: "Molekulare Genetik", Berlin, Dahlem Lines: 51 Message-ID: <315C1E8A.2781@mpimg-berlin-dahlem.mpg.de> NNTP-Posting-Host: rag2.rz-berlin.mpg.de (141.14.130.102) Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit NNTP-Posting-User: leser X-Access: 16 25 816 X-Mailer: Mozilla 2.0 (X11; I; OSF1 V3.0 alpha) Max-Planck-Institut fuer Molekulare Genetik ANNOUNCEMENT An X chromosome YAC map - IXDB release 1.0 - The X chromosome YAC map constructed at the ICRF Genome Analysis lab (London) and later at the Max-Planck-Institut fr Molekulare Genetik (Berlin) is now available. Approximately 125 Mb are covered (80 %) in 25 contigs, and include 906 YAC clones. The data is stored and graphically displayed in an acedb database (version 4.1) named IXDB release 1.0. To facilitate the integration and comparison with other maps from the X chromosome community, we have kept the same scale and banding pattern as for the consensus map constructed at the last X chromosome workshop. To access the data, simply connect to http://www.mpimg-berlin-dahlem.mpg.de/~xteam using a World Wide Web browser. Follow the instructions to first install the acedb program on your local computer, and then download the X chromosome data from our server. The database contains results from about 2000 hybridisations, 972 gel fingerprints of Alu-PCR products and 172 FISH mapping experiments. We strongly encourage you to also download the X chromosome subset of the Integrated Genome Database (IGD), fully compatible with our dataset. This will enable you to merge the experimental YAC mapping data with information from GDB, OMIM, EMBL, RLDB, and other genome related databases in a single step. Dept. H. Lehrach Max-Planck-Institut fuer Molekulare Genetik Ihnestrasse 73 14195 Berlin Germany _____________________________________________________________________ Hugues Roest Crollius Tel: +49 30 8413 1612 Abt. Lehrach FAX: +49 30 8413 1380 Max-Planck-Institut fuer Molekulare Genetik Ihnestrasse 73 14195 Berlin Germany e-mail: roest@mpimg-berlin-dahlem.mpg.de _____________________________________________________________________ From owner-chromosomes@net.bio.net Sun Mar 31 23:00:00 1996 Path: biosci!rutgers!gatech!newsfeed.internetmci.com!in2.uu.net!brighton.openmarket.com!decwrl!waikato!midland.co.nz!newsource.ihug.co.nz!usenet From: anghara@ihug.co.nz (Alma Hromic) Newsgroups: bionet.genome.chromosomes Subject: long arm of fourth chromosome Date: 1 Apr 1996 07:52:25 GMT Organization: The Internet Group Lines: 8 Message-ID: <4jo1vp$91u@newsource.ihug.co.nz> Reply-To: anghara@ihug.co.nz NNTP-Posting-Host: ppp183.ihug.co.nz Mime-Version: 1.0 X-Newsreader: WinVN 0.99.4 Help! I have a friend with a learning-impaired daughter who has just had a blood test and has been diagnosed as having the long arm of chromosome 4 deleted. Does anyone know anything about this deletion and what effect it might have on people? Any information gratefully received. Alma