From owner-chromosomes@net.bio.net Tue Jan 07 22:00:00 1997 Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!arclight.uoregon.edu!enews.sgi.com!news.sgi.com!howland.erols.net!EU.net!Norway.EU.net!sn.no!news-stkh.gsl.net!news.gsl.net!news-paris.gsl.net!news.gsl.net!rain.fr!world-net!not-for-mail From: Timo Rinttila Newsgroups: bionet.genome.chromosomes Subject: Bacteria becomming resistant?? Date: Wed, 08 Jan 1997 18:57:57 +0100 Organization: sct.fr Lines: 6 Message-ID: <32D3E024.5A31@worldnet.fr> Reply-To: timo-r@worldnet.fr NNTP-Posting-Host: 194.206.158.150 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01 (Win95; I) Hi, I'm doing an research paper on how Bacteria are comming resistant to antibiotics by the changes of plasmids. Does anyone have any information about this subject? Timo Rinttila timo-r@worldnet.fr From owner-chromosomes@net.bio.net Tue Jan 07 22:00:00 1997 Path: biosci!agate!howland.erols.net!news.sprintlink.net!news-peer.sprintlink.net!uunet!in3.uu.net!198.151.175.33!news.xensei.com!news From: chi@healthtech.com (Cambridge Healthtech Institute) Newsgroups: bionet.genome.chromosomes Subject: HUMAN GENOME PROJECT EUROPE: Genomes, Diseases, Drugs, and Diagnostics Date: Wed, 08 Jan 1997 19:02:09 GMT Organization: Cambridge Healthtech Institute Lines: 74 Message-ID: <5b0rir$47u@xensei3.xensei.com> Reply-To: chi@healthtech.com NNTP-Posting-Host: chi.xensei.com X-Newsreader: Forte Free Agent 1.0.82 If you wish to recieve an update program and registration form, please contact: Cambridge Healthtech Institute 1037 Chestnut Street Newton Upper Falls, MA 02164 Phone :617-630-1300 Fax: 617-630-1325 E-mail: chi@healthtech.com http://www.healthtech.com/conferences/ Cambridge Healthtech Institute's HUMAN GENOME PROJECT EUROPE: Genomes, Diseases, Drugs, and Diagnostics May 19-21, 1997 Loews Hotel Monte Carlo Monte Carlo, Monaco Corporate Sponsor Perkin-Elmer, Applied Biosystems Division Pharmacia-Biotech AB Merck Research Laboratories Corporate Support Glaxo Wellcome Genset Scientific Advisory Board Dr. David Bailey, Pfizer Central Research Dr. Colin Dykes, Glaxo-Wellcome Dr. Chris Sander, European Molecular Biology Laboratory Dr. Alan Williamson, Merck Research Laboratories Genome Sequencing Contributions of CEPH to the Human Genome Project Prof. Jean Dausset, CEPH Human Genome Sequencing Dr. David Buck, Sanger Center Human Disease Gene Hunting Gene Hunting in Human Diseases: From Gene Paradigms to Complex Traits Dr. Philippe Froguel, Institute Pasteur of Lille Using Positional Cloning to Find Disease Genes Dr. Tim Harris, Sequana Therapeutics Novel Platform for Clinical Mapping of Human Genome Dr. Steve Peroutka, Spectra Biomedical The Human Genome and Ethics Dr. Carmen Rauch, Hopital d'Enfants de la Timone Reducing Genomic Information to Drug Discovery Practice From Merck Gene Index to Information to Novel Drugs Dr. Alan Williamson, Merck Research Laboratories Medical Genomics: From Genes to Products Dr. William Haseltine, Human Genome Sciences Genomics and Pharmacogenomics Prof. Daniel Cohen, Genset Tumor Suppressor Genes: From Signaling Pathway Analysis To Drug Discovery Target Identification Dr. Bernd R. Seizinger, Genome Therapeutics Corporation From Genes to Screens Dr. Norman J.W. Russell, Zeneca Pharmaceuticals Parallel Drug Development with Gene Expression Micro-Arrays Dr. Dari Shalon, Synteni, Inc. Application of Diagnostics to Non-Infectious Diseases: Connecting Genes to Diseases Use of SAGE Technology to Analyze Colorectal Cancer Dr. Lin Zhang, Johns Hopkins University School of Medicine Expression Measurement by "Hybridization Signature" Methods Dr. Bertrand Jordan, Centre d'Immunologie, INSERM/CNRS Identification of Disease-Associated Genes Using High-Density cDNA Arrays From owner-chromosomes@net.bio.net Wed Jan 08 22:00:00 1997 Path: biosci!rutgers!gatech!csulb.edu!hammer.uoregon.edu!news-peer.gsl.net!news.gsl.net!news-penn.gsl.net!news.gsl.net!news.NetVision.net.il!news From: Mark Klein Newsgroups: bionet.cellbiol.cytonet,bionet.general,bionet.genome.chromosomes Subject: FREE pH measurement booklet Date: 9 Jan 1997 10:43:25 GMT Organization: NetVision LTD. Lines: 9 Message-ID: <5b2i4d$2bp@news.NetVision.net.il> NNTP-Posting-Host: ts006p13.pop2a.netvision.net.il Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.2N (Windows; I; 16bit) Xref: biosci bionet.cellbiol.cytonet:755 bionet.general:25064 bionet.genome.chromosomes:1491 A free pH booklet is available which contains valuable information on basic pH measurement theory, pH measurement techniques, selecting the proper pH electode for a particular application, and a pH troubleshooting guide. The booklet is available from Lazar Research Labs. Inc. by emailing service@lazarlab.com or faxing 1-213-931-1434. The booklet can also be obtained from the Lazar web site at http://www.lazarlab.com From owner-chromosomes@net.bio.net Wed Jan 08 22:00:00 1997 Path: biosci!agate!howland.erols.net!worldnet.att.net!arclight.uoregon.edu!news.bbnplanet.com!su-news-hub1.bbnplanet.com!su-news-feed4.bbnplanet.com!news1.slip.net!not-for-mail From: Michael Alden Newsgroups: bionet.genome.chromosomes Subject: genetics Date: Thu, 09 Jan 1997 07:30:49 -0800 Organization: Alden Computing Consultants Lines: 19 Message-ID: <32D50F28.198D@slip.net> Reply-To: alden@slip.net NNTP-Posting-Host: sr-pm1-29-249.dialup.slip.net Mime-Version: 1.0 Content-Type: multipart/alternative; boundary="----------2B5B320563D00" X-Sender: Michael Alden (Unverified) X-Mailer: Mozilla 4.0b1 (Win95; I) X-Priority: Normal ------------2B5B320563D00 Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=us-ascii ------------2B5B320563D00 Content-Transfer-Encoding: 7bit Content-Type: text/html; charset=us-ascii
 
------------2B5B320563D00-- From owner-chromosomes@net.bio.net Sat Jan 11 22:00:00 1997 Path: biosci!daresbury!not-for-mail From: Rifat Hamoudi Newsgroups: bionet.genome.chromosomes Subject: Sequencing directly from PACs & YACs Date: 12 Jan 1997 14:58:23 -0000 Lines: 14 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <5bau6f$kiv@mserv1.dl.ac.uk> Delivery-Receipt-To: Rifat Hamoudi MIME-Version: 1.0 X-Authentication: IMSP Original-To: biochrom@dl.ac.uk Hi, Has anyone managed to auto sequence directly from PACs and/or YACs. If so i would be grateful for any advise on reaction conditions and template concentrations and primer concentrations used. Thanks. Rifat. rifat@icr.ac.uk From owner-chromosomes@net.bio.net Sun Jan 12 22:00:00 1997 Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!feed1.news.erols.com!news.idt.net!nntp.farm.idt.net!news From: cybek@mail.idt.net (William Theaux) Newsgroups: bionet.genome.chromosomes Subject: Laymen’s association search for DNA information Date: Mon, 13 Jan 1997 22:09:06 GMT Organization: IDT Lines: 8 Message-ID: <5bebm3$7ql@nnrp1.farm.idt.net> Reply-To: cybek@mail.idt.net NNTP-Posting-Host: ppp-31.ts-15.nyc.idt.net X-Newsreader: Forte Free Agent 1.0.82 Independant association of people who want to preserve their DNA by themselves are searching for conservation technic. We have heard about some very simple and safe non-cryogenic proceduresf - anyone with information, please contact us. Thanks. CYBEK\William Theaux From owner-chromosomes@net.bio.net Tue Jan 14 22:00:00 1997 Path: biosci!daresbury!nntp-trd.UNINETT.no!sn.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!enews.sgi.com!news.sgi.com!news.msfc.nasa.gov!bcm.tmc.edu!news From: Kim Worley Newsgroups: bionet.genome.chromosomes Subject: Re: Chr12 sequence information Date: Wed, 15 Jan 1997 13:59:30 -0500 Organization: Baylor College of Medicine Lines: 20 Message-ID: <32DD2912.2EDB@bcm.tmc.edu> References: NNTP-Posting-Host: hen.imgen.bcm.tmc.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.0 (X11; I; SunOS 5.5 sun4m) The Chromosome 12 Genome Center, a collaborative research effort of the Albert Einstein College of Medicine and the Yale University School of Medicine has targeted to sequence 12q13. Hugo (http://hugo.gdb.org/hsmindex.htm) had no mention of 12q14. Kim Worley Michael C. Gorry wrote: > > I am interested in finding any sequence information for 12q13-14. Are > there any projects currently sequencing this region? > > Thanks > > MIke > > -- > Michael Gorry > mcgorry@med.pitt.edu From owner-chromosomes@net.bio.net Tue Jan 14 22:00:00 1997 Path: biosci!rutgers!news.sgi.com!howland.erols.net!netnews.com!news.intercon.com!news5.digex.net!haven.umd.edu!purdue!oitnews.harvard.edu!das-news2.harvard.edu!fas-news.harvard.edu!slippp2-20.fas.harvard.edu!user From: bttran@law.harvard.edu (tran) Newsgroups: bionet.genome.chromosomes Subject: behavioral differences in the sexes and biology Date: Wed, 15 Jan 1997 08:26:02 -0500 Organization: Harvard University, Cambridge, Massachusetts Lines: 8 Message-ID: NNTP-Posting-Host: slippp2-20.fas.harvard.edu I'm taking a gender class and need to prsent the perspective that some behavioral differences between men and women are the result of biological differences and not the result of socialization. Please share your perspective on this, and provide me with any scientific data, studies, or articles that support this view or refutes it. I thank you in advance for your input. Please e-mail me with any information you can provided. My e-mail address is bttran@law.harvard.edu. The class will end on January 24th. Thank you. From owner-chromosomes@net.bio.net Tue Jan 14 22:00:00 1997 Path: biosci!ihnp4.ucsd.edu!swrinde!news.sgi.com!csulb.edu!hammer.uoregon.edu!arclight.uoregon.edu!news.bbnplanet.com!su-news-hub1.bbnplanet.com!newsxfer3.itd.umich.edu!portc01.blue.aol.com!newsstand.cit.cornell.edu!news.acsu.buffalo.edu!dsinc!newsfeed.pitt.edu!quadra950.pathology.pitt.edu!user From: mcgorry@med.pitt.edu (Michael C. Gorry) Newsgroups: bionet.genome.chromosomes Subject: Chr12 sequence information Date: 15 Jan 1997 00:51:06 GMT Organization: Univ of Pittsburgh, Center for Genomic Science Lines: 10 Message-ID: NNTP-Posting-Host: quadra950.pathology.pitt.edu I am interested in finding any sequence information for 12q13-14. Are there any projects currently sequencing this region? Thanks MIke -- Michael Gorry mcgorry@med.pitt.edu From owner-chromosomes@net.bio.net Wed Jan 15 22:00:00 1997 Path: biosci!daresbury!not-for-mail From: Stephane.Pasteau@pasteur-lille.fr (Stephane Pasteau) Newsgroups: bionet.genome.chromosomes Subject: Duck female specific nucleic probe Date: 16 Jan 1997 11:10:18 -0000 Lines: 17 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <5bl2aq$f1j@mserv1.dl.ac.uk> Original-To: biochrom@dl.ac.uk I'm looking for a nucleic probe that I could use for sexing a duck female. I know that it exists specic probes on chicken W chromosome. Does anybody know if probes like that exist for the duck and if not, can I use chicken probes on the duck. Last question, could anybody give me such a probe. Thank you in advance for answers (you can use my email) Dr Stephane PASTEAU Institut Pasteur de Lille Service de Recherche et D=E9veloppement Domaine du CERTIA 369, rue Jules Guesde - B.P. 39 59651 VILLENEUVE D'ASQ cedex tel. : (33) 03-20-43-86-67 fax. : (33) 03-20-43-86-66 e.mail : Stephane.Pasteau@pasteur-lille.fr From owner-chromosomes@net.bio.net Wed Jan 15 22:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.sgi.com!news-out.microserve.net!news-in.microserve.net!news-xfer.netaxs.com!feed1.news.erols.com!arclight.uoregon.edu!leto!news.ou.edu!news.ecn.uoknor.edu!news.ysu.edu!odin.oar.net!malgudi.oar.net!nike.heidelberg.edu!NewsWatcher!user From: bhenders@nike.heidelberg.edu (Bethany Henderson) Newsgroups: bionet.genome.chromosomes Subject: request:chromosome 7 Date: 16 Jan 1997 22:54:36 GMT Organization: Heidelberg College Lines: 5 Message-ID: NNTP-Posting-Host: 141.139.3.28 I'm a college student at Heidelberg College. I'm looking for information on chromosome 7. Any information that you could give me would be of great help. Thank you for your time. Bethany Henderson From owner-chromosomes@net.bio.net Wed Jan 15 22:00:00 1997 Path: biosci!mad.adelaide.edu.au!rwallace From: rwallace@mad.adelaide.edu.au (Robyn Wallace) Newsgroups: bionet.genome.chromosomes Subject: chromosome 18 Date: 15 Jan 1997 19:45:47 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 23 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Is anyone working on integrating chromosome 18 genetic markers into one map. I am having difficulty determining the order and distance between markers from different sources (eg Weber, Gyapay, etc). Any help (or perhaps a www address!) is greatly appreciated. ============================================================================ Robyn Wallace Department of Cytogenetics and Molecular Genetics Womens and Childrens Hospital North Adelaide, South Australia 5006 Ph 61 08 204 6442 Fax 61 08 204 7342 Email rwallace@mad.adelaide.edu.au ============================================================================ From owner-chromosomes@net.bio.net Thu Jan 16 22:00:00 1997 Path: biosci!U.WASHINGTON.EDU!kswiss From: kswiss@U.WASHINGTON.EDU (Karen Swisshelm) Newsgroups: bionet.genome.chromosomes Subject: Re: Laymens association search for DNA information Date: 16 Jan 1997 18:37:23 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 25 Sender: daemon@net.bio.net Distribution: world Message-ID: References: <5bebm3$7ql@nnrp1.farm.idt.net> NNTP-Posting-Host: net.bio.net Reply to William Theaux: I saw your request for DNA storage information. Your resource is in Seattle, a Ph.D. who has been a leader in DNA storage since 1992. He is reliable, efficient, and has a price well below what any other laboratory would charge. His name is Dr. James Bicknell and can be reached at 73021,506@compuserve.com Karen Swisshelm Dept. of Pathology University of Washington Seattle. WA On Mon, 13 Jan 1997, William Theaux wrote: > > Independant association of people who want to preserve their DNA by > themselves are searching for conservation technic. We have heard about > some very simple and safe non-cryogenic proceduresf - anyone with > information, please contact us. Thanks. > > CYBEK\William Theaux > > > From owner-chromosomes@net.bio.net Thu Jan 16 22:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!news.sgi.com!news.sprintlink.net!news-peer.sprintlink.net!uunet!in2.uu.net!198.151.175.33!news.xensei.com!news From: chi@healthtech.com (Cambridge Healthtech Institute) Newsgroups: bionet.genome.chromosomes Subject: Gene Transcription and Therapeutic Intervention Date: Fri, 17 Jan 1997 14:26:24 GMT Organization: Cambridge Healthtech Institute Lines: 119 Message-ID: <5bo2vd$fga@xensei3.xensei.com> Reply-To: chi@healthtech.com NNTP-Posting-Host: chi.xensei.com X-Newsreader: Forte Free Agent 1.0.82 If you wish to receive more information please contact: Cambridge Healthtech Institute 1037 Chestnut Street Newton Upper Falls, MA 02164 Phone: 617-630-1300 Fax: 617-630-1325 E-mail: chi@healthtech.com http://www.healthtech.com/conferences/ Gene Transcription and Therapeutic Intervention June 2-3, 1997 The Loews L’Enfant Plaza, Washington D.C. Regulation of gene transcription lies in the heart of signal transduction process. Changes in cell behavior during health and disease induced by growth factors or cytokines, require execution of selective gene transcription. Significant progress has been made in our understanding of how extracellular or intracellular signals can regulate sets of genes in a selective fashion. Cloning and identification of novel transcription factors (from genomics projects) gives us the opportunity for developing pioneering therapeutic approaches. Development of agents that regulate gene expression represent a new and unexploited area for small molecule therapeutics. Selective regulation of transcription with small molecules will emerge as a dominant gene therapy mode in 21st century. This conference brings together leaders in the field of transcription regulation, both from academia and industry. First session deals with basic aspect of signal transduction, gene regulation and its importance in drug development. Enormous progress has been made in nuclear receptor function and how they are used as models for transcription factors-drug interaction. Sessions are also planned that discuss roles of specific transcription factors in diseases, for example, cancer, cardiovascular disease and inflammation. Pathogen transcription apparatus is discussed as a therapeutic target from fungal and bacterial and viral perspective. A full session is devoted to exciting development from genomics and its impact in generation of transcription factors as drug targets. Signal Transduction and Transcription Regulation Regulation of Transcription: An Emerging New Area for Therapeutic Intervention Dr. Tauseef R. Butt, Gene Transcription Technologies; University of Pennsylvania School of Medicine (confirmed) In Vivo and In Vitro Analyses of the hsp70 Heat Shock Gene Promoter in Drosophila Dr. David S. Gilmour, The Pennsylvania State University (confirmed) Lac Repressor: A Model Transcription Factor with Fascinating Regulatory Modes of Action Dr. Mitch Lewis, University of Pennsylvania Medical School Activation of Latent Transcription Factors in Response to Signal Transduction Dr. Joseph Didonato, University of California School of Medicine Nuclear Receptors as Model Transcription Factors Human Estrogen Receptor: A Rich History of a Receptor With Multiple Physiological Effects Dr. Leslie Pike, University of Cincinnati Nuclear Receptor Coregulatory Proteins: A New Frontier of Hormone Action and Transcriptional Regulation Dr. Paul G. Walfish, University of Toronto Medical School and Mount Sinai Hospital(confirmed) Androgen Receptor and Co-activator Interaction Dr. Chawshang Chang University of Wisconsin Expression of PPARs and Their Role in Physiology Dr. Walter Wahli, University of Lausanne Emerging Concepts and Bioinformatics Approaches in Transcription Regulation Advanced Data Management Tools for the Study of Gene Expression Dr. G. Christian Overton, University of Pennsylvania (confirmed) Patterns of Gene Expression: A Bioinformatics Approach to Identifying Master Transcription Regulators Dr. Frank Tobin, SmithKline Beecham Pharmaceuticals (tentative) Gene Expression Micro-Arrays: A New Tool for Genomics Dr. Deval A. Lashkari, Synteni, Inc. (confirmed) Sequencing and Analysis of Human Regulatory Regions Dr. Marc Vasseur, Genset (confirmed) Transcription Regulation: The Other End of Gene Therapy Challenge Dr. Inder Verma, The Salk Institute Transcription Factors, Apparatus and Therapeutic Intervention Rapid Screening of DNA Binding Molecules in Developing Small Molecule Gene-regulating Drugs Dr. Cynthia Edwards, Genelabs Technologies, Inc. Microbial Transcription Apparatus as a Novel Antimicrobial Drug Target Dr. C. Richard Wobbe, Scriptgen Pharmaceutical (confirmed) Activation of RXR Pathway Modulates Apoptosis in Myeloid and Lymphoid Cells Dr. Richard A. Heyman, Ligand Pharmaceuticals E2F Transcription Factor as Anticancer Targets Dr. Roberto Wienman, Bristol-Myers Squibb Pharmaceutical Research Institute (confirmed) Topic to be Determined Dr. David Kirn, Onyx Pharmaceuticals Oncogene Sciences, Inc. Regulation of HDL Gene Expression and Cardiovascular Function Dr. Sotirios K. Karathanasis, Wyeth-Ayerst Research (confirmed) Peroxisome Proliferator Receptor Modulating Drugs and Their Role in the Treatment of Non-Insulin Dependent Diabetes Dr. Paul Young, SmithKline Beecham Pharmaceuticals (confirmed) Therapeutic Intervention of Cytokine Signaling: Molecular Targets and Screening Strategies Dr. Casey C. Case, Tularik, Inc. (confirmed) Complex Regulation of NF-Kappa B During the Inflammatory Response Dr. Steven M. Taffet, State University of New York Health Science Center at Syracuse (confirmed) NF-AT Family of Transcription Factors and Cytokine Gene Regulation Dr. Anjana Rao, Harvard Medical School From owner-chromosomes@net.bio.net Thu Jan 16 22:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!feed1.news.erols.com!howland.erols.net!newspump.sol.net!mindspring!uunet!in2.uu.net!204.96.36.2!wizard.pn.com!news.xensei.com!news From: chi@healthtech.com (Cambridge Healthtech Institute) Newsgroups: bionet.genome.chromosomes Subject: HUMAN GENOME PROJECT EUROPE: Genomes, Diseases, Drugs, and Diagnostics Date: Fri, 17 Jan 1997 12:50:41 GMT Organization: Cambridge Healthtech Institute Lines: 74 Message-ID: <5bntbu$ce9@xensei3.xensei.com> Reply-To: chi@healthtech.com NNTP-Posting-Host: chi.xensei.com X-Newsreader: Forte Free Agent 1.0.82 If you wish to recieve an update program and registration form, please contact: Cambridge Healthtech Institute 1037 Chestnut Street Newton Upper Falls, MA 02164 Phone :617-630-1300 Fax: 617-630-1325 E-mail: chi@healthtech.com http://www.healthtech.com/conferences/ Cambridge Healthtech Institute's HUMAN GENOME PROJECT EUROPE: Genomes, Diseases, Drugs, and Diagnostics May 19-21, 1997 Loews Hotel Monte Carlo Monte Carlo, Monaco Corporate Sponsor Perkin-Elmer, Applied Biosystems Division Pharmacia-Biotech AB Merck Research Laboratories Corporate Support Glaxo Wellcome Genset Scientific Advisory Board Dr. David Bailey, Pfizer Central Research Dr. Colin Dykes, Glaxo-Wellcome Dr. Chris Sander, European Molecular Biology Laboratory Dr. Alan Williamson, Merck Research Laboratories Genome Sequencing Contributions of CEPH to the Human Genome Project Prof. Jean Dausset, CEPH Human Genome Sequencing Dr. David Buck, Sanger Center Human Disease Gene Hunting Gene Hunting in Human Diseases: From Gene Paradigms to Complex Traits Dr. Philippe Froguel, Institute Pasteur of Lille Using Positional Cloning to Find Disease Genes Dr. Tim Harris, Sequana Therapeutics Novel Platform for Clinical Mapping of Human Genome Dr. Steve Peroutka, Spectra Biomedical The Human Genome and Ethics Dr. Carmen Rauch, Hopital d'Enfants de la Timone Reducing Genomic Information to Drug Discovery Practice From Merck Gene Index to Information to Novel Drugs Dr. Alan Williamson, Merck Research Laboratories Medical Genomics: From Genes to Products Dr. William Haseltine, Human Genome Sciences Genomics and Pharmacogenomics Prof. Daniel Cohen, Genset Tumor Suppressor Genes: From Signaling Pathway Analysis To Drug Discovery Target Identification Dr. Bernd R. Seizinger, Genome Therapeutics Corporation From Genes to Screens Dr. Norman J.W. Russell, Zeneca Pharmaceuticals Parallel Drug Development with Gene Expression Micro-Arrays Dr. Dari Shalon, Synteni, Inc. Application of Diagnostics to Non-Infectious Diseases: Connecting Genes to Diseases Use of SAGE Technology to Analyze Colorectal Cancer Dr. Lin Zhang, Johns Hopkins University School of Medicine Expression Measurement by "Hybridization Signature" Methods Dr. Bertrand Jordan, Centre d'Immunologie, INSERM/CNRS Identification of Disease-Associated Genes Using High-Density cDNA Arrays From owner-chromosomes@net.bio.net Fri Jan 17 22:00:00 1997 Path: biosci!daresbury!nntp-trd.UNINETT.no!hermod.uio.no!nntp.uio.no!newsfeeds.sol.net!uwm.edu!fnnews.fnal.gov!nntp-server.caltech.edu!news From: "Dr. Ung-Jin Kim" Newsgroups: bionet.genome.chromosomes Subject: Postdoctoral position at CalTech Genome Research Laboratory Date: Sat, 18 Jan 1997 12:00:37 -0800 Organization: CalTech Lines: 35 Message-ID: <32E12BE5.1F7C@caltech.edu> NNTP-Posting-Host: date.tree.caltech.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.5 sun4u) Caltech Genome Research Laboratory is looking for a postdoctoral fellow to work on developing technologies for advanced genomic research. We expect the person to work on human genome mapping and characterization, and participate in the development of new high density DNA arraying technology. The research will entail using computer-based data acquisition and analysis as well as molecular biology-related works. The position is open immediately. A Ph. D. degree in biological sciences and strong background in recombinant DNA techniques are desirable. Interested parties should send CV and to Dr. Kim. Electronic submissions are welcome (please send your CV in ascii format). Caltech provides employees with excellent work environment and benefit packages. We will notify the applicants if an interview is necessary soon after reviewing their applications. Please see our WEB page http://www.tree.caltech.edu for more information. *************************************************************** * * * Ung-Jin Kim, Ph.D. * * Director, Genome Research Laboratory * * Division of Biology, 147-75, Caltech, Pasadena, CA 91125 * * (818)395-4901 (office) (818)395-4154 (laboratory) * * (818)796-7066 (fax) (818)548-7555 (home) * * ung@caltech.edu http://date.tree.caltech.edu * * * *************************************************************** From owner-chromosomes@net.bio.net Fri Jan 17 22:00:00 1997 Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!newsfeeds.sol.net!newspump.sol.net!howland.erols.net!EU.net!Germany.EU.net!main.Germany.EU.net!news-koe1.dfn.de!uni-muenster.de!cuba.uni-muenster.de!hohoff From: "Carsten Hohoff" Newsgroups: bionet.genome.chromosomes Subject: mouse chromosome Date: Sat, 18 Jan 1997 18:19:49 +0100 Organization: Westfaelische Wilhelms-Universitaet Muenster, Germany Lines: 13 Sender: "Carsten Hohoff" Message-ID: NNTP-Posting-Host: cuba.uni-muenster.de Mime-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII What mouse chromosone is homologous to human chromosome 17? Carsten Hohoff Department of Biochemistry University of Muenster Wilhelm-Klemm-Str. 2 D-48149 Muenster Phone: ++49-251-8333209 Fax: ++49-251-8333206 E-Mail: hohoff@uni-muenster.de From owner-chromosomes@net.bio.net Fri Jan 17 22:00:00 1997 Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!newsfeeds.sol.net!uwm.edu!fnnews.fnal.gov!nntp-server.caltech.edu!news From: "Dr. Ung-Jin Kim" Newsgroups: bionet.genome.chromosomes Subject: Staff scientist positions at CalTech Genome Research Lab. Date: Sat, 18 Jan 1997 12:08:07 -0800 Organization: CalTech Lines: 51 Message-ID: <32E12DA7.9A1@caltech.edu> NNTP-Posting-Host: date.tree.caltech.edu Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.0 (X11; I; SunOS 5.5 sun4u) Job 1: We are looking for a few lab assistants Caltech Genome Research Laboratory is looking for qualified full time technicians with experiences in laboratory works involving recombinant DNA procedures. Works will require skills in colony hybridization, PCR screening of genomic libraries, DNA preparation, restriction fingerprint analysis, and more. Positions are open immediately. A college degree in Biological sciences or other sciences required. Interested parties should send CV and salary requirement to Dr. Ung-Jin Kim Electronic submissions are welcome (please send your CV in ascii format). Job 2: We are looking for a bioinformatician Caltech Genome Research Laboratory is looking for a full time informatician to manage and analyze laboratory data, and help operate robotic workstations. Knowledge and experieince in handling biological information, especially in the analysis and management of physcal mapping and DNA sequence data is essential. Familiarity with ACeDB database is critical. We also expect the person to be familiar with Unix platforms as well as PC/MacIntosh. Interested parties should send CV and salary history to Dr. Kim. Electronic submissions are welcome (please send your CV in ascii format). Caltech provides employees with excellent work environment and benefit packages. We will notify the applicants if an interview is necessary soon after reviewing their applications. Please see our WEB page http://www.tree.caltech.edu for more information. *************************************************************** * * * Ung-Jin Kim, Ph.D. * * Director, Genome Research Laboratory * * Division of Biology, 147-75, Caltech, Pasadena, CA 91125 * * (818)395-4901 (office) (818)395-4154 (laboratory) * * (818)796-7066 (fax) (818)548-7555 (home) * * ung@caltech.edu http://date.tree.caltech.edu * * * *************************************************************** From owner-chromosomes@net.bio.net Sat Jan 18 22:00:00 1997 Path: biosci!agate!howland.erols.net!torn!ccshst05.cs.uoguelph.ca!wright.aps.uoguelph.ca!yeganehh From: yeganehh@wright.aps.uoguelph.ca (Hassan Mehrabani-Yeganeh) Newsgroups: bionet.genome.chromosomes Subject: How to increase buffer size for LaTeX Date: 19 Jan 1997 19:16:16 GMT Organization: University of Guelph Lines: 25 Message-ID: <5btru0$oi@ccshst05.cs.uoguelph.ca> NNTP-Posting-Host: wright.aps.uoguelph.ca X-Newsreader: TIN [version 1.2 PL2] Subject: How to increase buffer size for LaTeX Newsgroups: comp.msdos.programmer Summary: Keywords: X-Newsreader: TIN [version 1.2 PL2] Subject: How to increase buffer size for LaTeX Newsgroups: comp.text.tex Summary: Keywords: X-Newsreader: TIN [version 1.2 PL2] Dear fellow LaTeX users. I have created an eps file with GNUplot and \input it into a LaTeX file. When I run LaTeX on it I receive the followin message: Tex Capacity exceeded [buffer size=4096] I am running LaTeX 2.09 under DOS. I appreciate it if you could send me a remedy either something related to DOS or to LaTeX itself. Best Regards, Hassan -- From owner-chromosomes@net.bio.net Sat Jan 18 22:00:00 1997 Path: biosci!U.WASHINGTON.EDU!kswiss From: kswiss@U.WASHINGTON.EDU (Karen Swisshelm) Newsgroups: bionet.genome.chromosomes Subject: Re: Laymens association search for DNA information Date: 19 Jan 1997 13:33:32 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 4 Sender: daemon@net.bio.net Distribution: world Message-ID: References: NNTP-Posting-Host: net.bio.net The correct email for DNA preparation is 73021.506@CompuServe.COM. Dr. James Bicknell, Seattle, WA. From owner-chromosomes@net.bio.net Tue Jan 21 22:00:00 1997 Path: biosci!bcm.tmc.edu!cs.utexas.edu!howland.erols.net!newsfeed.internetmci.com!newsfeed.direct.ca!nntp.portal.ca!van-bc!n1van.istar!van.istar!west.istar!ott.istar!istar.net!tor.istar!east.istar!news From: Stephanie St-Pierre Newsgroups: bionet.genome.chromosomes Subject: #11 & #19 chrom. Date: 22 Jan 1997 21:20:25 GMT Organization: International 11;22 Translocation Network Lines: 6 Message-ID: <5c60ap$8sd@nr1.toronto.istar.net> NNTP-Posting-Host: timmins-190.nt.net Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 2.01KIT (Win16; U) Hi, I'm looking for a friend of mine, for any match for her son...he has 11q+ and 19q- syndrome. I know it's a long shot, but any info would be appreicted. Please e-mail me directly, stpierre@nt.net. Thanks, Stephanie From owner-chromosomes@net.bio.net Thu Jan 23 22:00:00 1997 Path: biosci!rutgers!news-server.ncren.net!newsgate.duke.edu!news.duq.edu!newsfeed.pitt.edu!quadra800.pathology.pitt.edu!user From: rapr@med.pitt.edu (Robert Preston) Newsgroups: bionet.genome.chromosomes Subject: Re:: ALEXIS NZILA Date: Fri, 24 Jan 1997 15:20:53 -0500 Organization: U.Pittsburgh Sch. Med. Lines: 27 Distribution: world Message-ID: References: <32E8D7B9.2D59@users.africaonline.co.ke> NNTP-Posting-Host: quadra800.pathology.pitt.edu In article <32E8D7B9.2D59@users.africaonline.co.ke>, wellcome@USERS.AFRICAONLINE.CO.KE ("Wellcome Trust Research Labs, Nairobi") wrote: edits > to 50 times more. How can someone explain this difference in the PCR > efficiency. The gene target is the same only the site of primers > annealing differs. Moreover, Tm primers are quite similar and I used very > low Tm (40 °C) for amplification. edits PCR is an exponential process. A very slight difference in efficiency per cycle can easily make the difference between results and no results in any exponential process. Forty degrees annealing is way too low for those primer Tm's... most likely you're getting non-specific amplification that diminishes the efficiency. Try raising the annealing temp to 55 or even 60 C. R.A.Preston Univ Pittsburgh -- Rob Preston Pittsburgh, PA rapr@med.pitt.edu From owner-chromosomes@net.bio.net Thu Jan 23 22:00:00 1997 Path: biosci!USERS.AFRICAONLINE.CO.KE!wellcome From: wellcome@USERS.AFRICAONLINE.CO.KE ("Wellcome Trust Research Labs, Nairobi") Newsgroups: bionet.genome.chromosomes Subject: ADVICE FOR PCR: ALEXIS Date: 24 Jan 1997 01:15:59 -0800 Organization: Wellcome Trust Research Labs Lines: 21 Sender: daemon@net.bio.net Distribution: world Message-ID: <32E8D7B9.2D59@users.africaonline.co.ke> NNTP-Posting-Host: net.bio.net To the news group I am amplifying 2 fragments of an unique DNA sequence of malaria; pfmdr1 gene with 2 different sets of primers. All primers are 21 nucleotides length .Set1 primers have Tm of 59 and 61 °C and Set2 have 61.7 and 51.2°C. PCR is carried out in standard condition and the Tm=40 °C. Using a same amount of DNA template (5 ul) of purified culture DNA, only Set2 give an amplification. Set1 give an amplification if the template is 20 to 50 times more. How can someone explain this difference in the PCR efficiency. The gene target is the same only the site of primers annealing differs. Moreover, Tm primers are quite similar and I used very low Tm (40 °C) for amplification. So, when amount of DNA is not high (naturally infected sample), Set2 can not amplify the gene however Set1 does. Is there a problem in my PCR condition? As the PCR conditions are the same for the 2 sets, why this difference? Alexis FOR ANSWER: PLEASE PRECISE MESSAGE FOR ALEXIS NZILA From owner-chromosomes@net.bio.net Fri Jan 24 22:00:00 1997 Path: biosci!rutgers!gatech!arclight.uoregon.edu!feed1.news.erols.com!howland.erols.net!swrinde!sdd.hp.com!hamblin.math.byu.edu!acs2.byu.edu!usenet From: "Roberto Galindo" Newsgroups: bionet.genome.chromosomes Subject: Re: Gene Transcription and Therapeutic Intervention Date: 25 Jan 1997 16:03:09 GMT Organization: Preferred Company Lines: 13 Message-ID: <01bc0ad9$29699ea0$2159c9cf@Robert.byu.edu> References: <5bo2vd$fga@xensei3.xensei.com> NNTP-Posting-Host: byur-033.ln.byu.edu X-Newsreader: Microsoft Internet News 4.70.1155 > Gene Transcription and Therapeutic Intervention > June 2-3, 1997 > The Loews L’Enfant Plaza, Washington D.C. > > Regulation of gene transcription lies in the heart of signal > transduction process. Changes in cell behavior during health > and disease induced by growth factors or cytokines, require > execution of selective gene transcription. Which signals (intracellular or ektracellular) regulate gene p53? Are those factors inherited? From owner-chromosomes@net.bio.net Sun Jan 26 22:00:00 1997 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.genome.chromosomes Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 27 Jan 1997 02:00:12 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 239 Sender: daemon@net.bio.net Distribution: world Message-ID: <199701271000.CAA18808@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. Sincerely, Dave Kristofferson BIOSCI/bionet Manager biosci-help@net.bio.net From owner-chromosomes@net.bio.net Sun Jan 26 22:00:00 1997 Path: biosci!CS.Arizona.EDU!news.Arizona.EDU!hamblin.math.byu.edu!acs2.byu.edu!news.cuny.edu!news.sprintlink.net!news-pen-15.sprintlink.net!cs.utexas.edu!news-xfer.netaxs.com!su-news-hub1.bbnplanet.com!news.bbnplanet.com!cpk-news-hub1.bbnplanet.com!cam-news-feed3.bbnplanet.com!adna.cshl.org!usenet From: David_Stewart Newsgroups: bionet.announce;,bionet.general;,bionet.genome;,bionet.molbio.genome-program;,bionet.molbio.methds-reagnts;,bionet.genome.arabidopsis;,bionet.genome.autosequencinq;,bionet.genome.chromosomes Subject: 1997 Genome Sequencing Course at Cold Spring Harbor Date: Mon, 27 Jan 1997 12:43:47 -0500 Organization: Cold Spring Harbor Laboratory Lines: 46 Message-ID: <32ECE953.26EC@cshl.org> Reply-To: meetings@cshl.org NNTP-Posting-Host: caracas.cshl.org Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.0 (Win95; I) CC: mccombie@cshl.org 1997 COLD SPIRNG HARBOR LABORATORY COURSE ADVANCED GENOME SEQUENCE ANALYSIS March 14 - 27, 1997 EXTENDED APPLICATION DEADLINE: JANUARY 31, 1997 Ellson Y. Chen, Perkin Elmer Corporation Richard Gibbs, Baylor College of Medicine W. Richard McCombie, Cold Spring Harbor Laboratory Richard K. Wilson, Washington University The purpose of the course is to teach students the range of techniques and project management skill required to carry out a large scale sequencing project. The course provides a two week, extensive laboratory experience in which the students work as a team to carry out a large-scale sequencing project. Recent advances in the automation of DNA sequencing have opened new possibilities for the analysis of complex genomes at the DNA sequence level. This two week course will provide intensive training in this rapidly evolving field. The course will emphasize techniques and strategies for using automated sequences to sequence large, contiguous genomic regions. Students will carry out all of the steps in the sequencing process from preparing cosmid DNA to computer analysis of the finished sequence. Topics will include subclone library generation, large-scale template purification, sequencing reactions, gel analysis on automated sequencers, sequence assembly, gap filling and conflict resolution, Students will work in groups to sequence a large region of DNA. For instance, in the first year's course a 45kb cosmid was sequenced (GenBank) accession #U23729). Through this process they will be trained in crucial project and data management techniques. A series of lecturers will discuss their applications of these techniques as well as alternate strategies for high speed automated DNA sequencing. Last year's speakers included: E. Chen, R. Gibbs, R. Mathies, W. McCombie, M. Metzger, B. Roe, M. Uhlen and R. Wilson. See the CSHL web site http://www.cshl.org/meetings/97c_info.htm for how to apply. -- Meetings & Courses Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 Tel 516 367 8346**Fax 516 367 8845**meetings@cshl.org general info at www.cshl.org/meeting/ ** general enquiries: meetings@cshl.org From owner-chromosomes@net.bio.net Tue Jan 28 22:00:00 1997 Path: biosci!rutgers!gatech!csulb.edu!hammer.uoregon.edu!arclight.uoregon.edu!worldnet.att.net!hunter.premier.net!news.lightlink.com!news.xensei.com!news From: chi@healthtech.com (Cambridge Healthtech Institute) Newsgroups: bionet.genome.chromosomes Subject: Fourth Annual HUMAN GENOME PROJECT: Commercial Implications Meeting Date: Wed, 29 Jan 1997 17:53:08 GMT Organization: Cambridge Healthtech Institute Lines: 106 Message-ID: <5co2t0$7o8@xensei3.xensei.com> Reply-To: chi@healthtech.com NNTP-Posting-Host: chi.xensei.com X-Newsreader: Forte Free Agent 1.0.82 For registration and hotel information please contact: Cambridge Healthtech Institute 1037 Chestnut Street Newton Upper Falls, MA 02164 USA Phone: 617-630-1300 Fax: 617-630-1325 E-mail: chi@healthtech.com http://www.healthtech.com/conferences/ Fourth Annual HUMAN GENOME PROJECT: Commercial Implications Meeting February 24-26, 1997 San Francisco, California Scientific Advisors Dr. Carol Dahl, National Cancer Institute Dr. Glen Evans, University of Texas Dr. Christopher Fields, National Center for Genome Resources Dr. Robert Strausberg, National Cancer Institute Overview: Where is Genomics Heading? Keynote Address: Dr. Ronald Davis, Stanford University School of Medicine Dr. Elbert Branscomb, Lawrence Livermore National Laboratory The Cancer Genome Anatomy Project: Dr. Robert L. Strausberg and Carol A. Dahl, National Cancer Inst. Computer-Aided Reconstruction of Extant and Ancient Metabolisms Based on Genome-Scale Protein Sequence Analysis: Dr. Archady Mushegian, National Center for Biotechnology Inform. The Investor's Roadmap to Profiting from the Genomics Revolution: Dr. Wolé M. Fayemi, Genesis Merchant Group Strategies for Sequencing the Human Genome Genomics Mapping and Clone End Sequencing- A Strategy for Efficient Completion of the Human Genome Sequence: Dr. Glen Evans, University of Texas Human Whole Genome Shotgun Sequencing: Dr. James Weber, Marshfield Medical Foundation Genome Analysis by Large Scale DNA Sequencing: Dr. Stephanie Chissoe, Washington University School of Medicine Dynamics of Gene Expression and Massively Parallel Signature Sequencing: Dr. David Martin Jr., Lynx Therapeutics High Throughput Technology for Biomolecular Analysis DNA Sequencing and Sizing by Mass Spectrometry: Dr. Christopher Becker, GeneTrace Systems Inc. High Throughput DNA Sequencing and Mapping Using Capillary Array Electrophoresis: Dr. David Barker, Molecular Dynamics Multiple Capillary Array Sequencers: Dr. Norman Dovichi, University of Alberta Single Molecular Approaches to Genomic Analysis: Dr. David Schwartz, New York University School of Medicine New Tools for Genetic Analysis: Dr. William Efcavitch, Perkin-Elmer Corporation Capillary Automated Submicroliter Sample Preparation: Dr. Deirdre R. Meldrum, University of Washington Emerging Genomic Strategies Genes, Chips, and the Human Genome: Dr. Stephen Fodor, Affymetrix DNA Sequence Manufacturing and Mining: The Industrial Age of Genomics: Dr. Randy Scott, Incyte Pharmaceuticals Human Genome Project: Next Generation Opportunities: Dr. Geoffrey Duyk, Millenium Pharmaceuticals (tentative) Towards Whole Genome Expression Analysis: Dr. Mark Schena, Stanford University Medical Center Gene to Screen: Accelerated Functional Analysis and Lead Discovery: Dr. Frank Craig, Aurora Biosciences Novel Platform for Clinical Mapping of Human Genome: Dr. Stephen Peroutka, Spectra Biomedical Identifying Genetic Networks Functional Genomics and CD-Taggingä: Dr. Jonathan Jarvik, Vyrex A Systematic Approach to the Identification of Surrogate Ligands for Seven Transmembrane, Orphan Receptors Using a Self-Selecting, Combinatorial Peptide Libraryãin Yeast: Dr. David R. Webb, Cadus Pharmaceutical Corporation Functional Genomics: Harnessing the Power of Genetics to Discover Gene Function: Dr. Corey Goodman, Exelixis Pharmaceuticals, Inc. Mining Genomes with Tandem Mass Spectrometry: Dr. John Yates, University of Washington The Genome Operating System and the Informatics of Protein Expression: Dr. Leigh Anderson, Large Scale Biology Corporation A Comprehensive Analysis of Yeast Cell Cycle Pathway: Dr. Gregory T. Went, CuraGen Corporation Genomic Drug Development Genomics: New Paradigms for Small Molecule Drug Discovery: Dr. Martin Rosenberg, SmithKline Beecham Pharmaceuticals Functional Genomics and Pharmacology: Prof. Marc Vasseur, Genset Discovery and Characterization of Novel Therapeutic Protein Candidates from Large cDNA Databases: Dr. Craig Rosen, Human Genome Sciences Use of Genomics in the Drug Discovery Process: Dr. Michael Fogliano, Pfizer Central Research From owner-chromosomes@net.bio.net Fri Jan 31 22:00:00 1997 Path: biosci!daresbury!nntp-trd.UNINETT.no!sn.no!nntp.uio.no!news.maxwell.syr.edu!insync!uunet!in1.uu.net!151.99.250.2!server-b.cs.interbusiness.it!usenet From: Giuliano Meini Newsgroups: bionet.genome.chromosomes Subject: xeroderma and heterozygotes Date: Sat, 01 Feb 1997 19:04:46 +0100 Organization: CIVICAE Lines: 4 Message-ID: <32F385BE.755E@tol.it> Reply-To: g.meini@tol.it NNTP-Posting-Host: ip046.tol04.interbusiness.it Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01Gold (Win95; I) i am a italian student. i am looking for bibliography about xeroderma and heterozygotes for mutation. Thank Tiziana Meini