From owner-chromosomes@net.bio.net Mon Mar 01 22:00:00 1999 From: "Hank Burr" Newsgroups: bionet.genome.chromosomes Subject: human 2,3 translocations Date: Tue, 2 Mar 1999 13:15:23 -0500 Lines: 7 X-Newsreader: Microsoft Outlook Express 4.72.3110.5 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 NNTP-Posting-Host: 206.175.51.149 Message-ID: <36dc2aab.0@news.netwalk.com> X-Trace: 2 Mar 1999 13:15:07 -0500, 206.175.51.149 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!newspeer.monmouth.com!dca1-hub1.news.digex.net!digex!WCG!arl-news-svc-3.compuserve.com!news-master.compuserve.com!compuserve.com!news.netwalk.com!206.175.51.149 Does anyone have information or literature references on human 2,3 translocations? Hank Burr hburr@0hiohills.com From owner-chromosomes@net.bio.net Tue Mar 02 22:00:00 1999 Path: biosci!AOL.COM!SPhil79466 From: SPhil79466@AOL.COM Newsgroups: bionet.genome.chromosomes Subject: Explosive New Marketing Strategy 800 607-6006 Ex 2492 Date: 2 Mar 1999 17:12:14 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 34 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net This is a 1 time mailing Fire the Boss and break the Alarm Clock! I did! after eleven years, I left a $140,000 a year income for this opportunity I can truly say it was one of the best decisions of my life!!! Never commute again! make $2000-$5000 per week from home with a turn key marketing system! To find out how our system works call the 800#. You can start out in your spare time, work part time or work up to full time if you want to! It's your business! Call 1-800 607-6006 ex 2492# then press 1 no selling! stay home with the family! Proven track record of success! 1 800-607-6006 ex 2492# call now! Profit From The Internet Growth-Explosion 800 607-6006 Ex 2492 Thank You From owner-chromosomes@net.bio.net Tue Mar 02 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.tli.de!newsfeed.nacamar.de!nntp.news.xara.net!xara.net!server6.netnews.ja.net!daresbury!not-for-mail From: SPhil79466@aol.com Newsgroups: bionet.genome.chromosomes Subject: Explosive New Marketing Strategy 800 607-6006 Ex 2492 Date: 3 Mar 1999 01:06:55 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 34 Message-ID: <7bi1vf$sfr$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk content-length: 716 Return-Path: Apparently-To: This is a 1 time mailing Fire the Boss and break the Alarm Clock! I did! after eleven years, I left a $140,000 a year income for this opportunity I can truly say it was one of the best decisions of my life!!! Never commute again! make $2000-$5000 per week from home with a turn key marketing system! To find out how our system works call the 800#. You can start out in your spare time, work part time or work up to full time if you want to! It's your business! Call 1-800 607-6006 ex 2492# then press 1 no selling! stay home with the family! Proven track record of success! 1 800-607-6006 ex 2492# call now! Profit From The Internet Growth-Explosion 800 607-6006 Ex 2492 Thank You From owner-chromosomes@net.bio.net Wed Mar 03 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!209.44.33.119!hub1.ispnews.com!news13.ispnews.com.POSTED!not-for-mail From: "Neel / Cameron" Newsgroups: bionet.genome.chromosomes References: <19990222185449.02887.00001811@ng-fx1.aol.com> Subject: Re: Hey PLEASE SOMEBODY ANWSER THIS!!! Lines: 13 X-Newsreader: Microsoft Outlook Express 4.72.3155.0 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3155.0 Message-ID: NNTP-Posting-Host: 209.144.27.139 X-Trace: news13.ispnews.com 920511799 209.144.27.139 (Wed, 03 Mar 1999 20:43:19 EDT) NNTP-Posting-Date: Wed, 03 Mar 1999 20:43:19 EDT Date: Wed, 3 Mar 1999 19:40:34 -0600 Males have one y and one x. Females have two x. Brookie624 wrote in message <19990222185449.02887.00001811@ng-fx1.aol.com>... >ok I need to know the anwser to this.. >IN X AND Y CHROMOSOMES WHICH IS THE MALE AND WHICH IS THE FEMALE...??? > >Thanx, >Brooke >P.S. Please anwser I am confused > From owner-chromosomes@net.bio.net Wed Mar 03 22:00:00 1999 From: MCG123@webtv.net (FREDERICK MCGRANTHAM) Newsgroups: bionet.genome.chromosomes Subject: TRANSLOCATION OF THE 2 & X CHROMOSOMES...PLEASE HELP Date: Thu, 4 Mar 1999 15:48:52 -0500 (EST) Organization: WebTV Subscriber Lines: 9 Message-ID: <13340-36DEF1B4-11@newsd-294.iap.bryant.webtv.net> NNTP-Posting-Host: localhost.webtv.net Mime-Version: 1.0 (WebTV) Content-Type: Text/Plain; Charset=US-ASCII Content-Transfer-Encoding: 7Bit X-WebTV-Signature: 1 ETAsAhQQDD5EhqaVN7eNv8w5WBw372RbYAIUWhkHDzBh6OqvusklDoULqBNuMFo= Content-Disposition: Inline Path: biosci!news.stanford.edu!su-news-feed4.bbnplanet.com!news.gtei.net!enews.sgi.com!news.sgi.com!news.spies.com!webtv.net!not-for-mail MY DAUGHTER WAS BORN 2 1/2 YRS AGO WITH A BALANCED TRANSLOCATION OF THE 2 & THE X CHROMOSOMES. SO FAR NONE OF THE DRS. OR GENETICISTS KNOW ANYTHING ABOUT THIS COMBO..RIGHT NOW SHE IS PRETTY NORMAL, HAPPY & HEALTHY WITH A FEW PHYSICAL ABNORMALITIES...PLEASE HELP WITH ANY INFO YOU MIGHT HAVE ON THIS SUBJECT. THANKS !!! HRE="http://www.slambook.com/slambooks/signsb.asp?sb=kmbrly"> From owner-chromosomes@net.bio.net Wed Mar 03 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!newsfeed1.earthlink.net!nntp.earthlink.net!posted-from-earthlink!not-for-mail From: Pablo Newsgroups: bionet.genome.chromosomes Subject: genetic theory in homosexuality Date: Wed, 03 Mar 1999 20:58:51 -0800 Content-Transfer-Encoding: 7bit X-Posted-Path-Was: not-for-mail Content-Type: text/plain; charset=us-ascii X-ELN-Date: 4 Mar 1999 04:57:00 GMT X-ELN-Insert-Date: Wed Mar 3 21:05:04 1999 Organization: EarthLink Network, Inc. Lines: 101 Mime-Version: 1.0 NNTP-Posting-Host: sdn-ar-004waseatp331.dialsprint.net Message-ID: <36DE130B.710408AC@earthlink.net> X-Mailer: Mozilla 4.05 [en] (Win95; I) The following is a discussion I recently had over the genetics or non genetics of homosexuality. I've reprinted it here in its original form and would like someone to critique my position, or just tell me why I'm plain wrong, and thus help me understand that, if it is or might be genetic, how the genetics work to sustain the homosexual population in society. Disclaimer: I am not, repeat NOT tying to make political statements with my argument. I'm purely interested in the science of the issue. Also, not being a scientist, my argument is based upon logical deduction, and a possible if not probable misunderstanding of how species genetics work. The other day, I got into a discussion with my girlfriend about homosexuality, and whether their sexual preference was genetic, or 'learned' behaviour. I suggested offhand that I believed that gay people become gay at a very early stage in life (too early to really pinpoint or control) due to experiences which cause them to not relate sexually to their biological opposites. This initially offended her, which in turn offended me because she felt it was too 'politically incorrect' to suggest that, as it further suggests that their behaviour is therefore 'deviant'. Well, unfortunately 'behavioral deviancy' had to be the furthest thing from my mind, but my girlfriend, being of the more 'politically correct' set, didn't see it that way so a tense discussion ensued. I told her that I was further disturbed that she was making scientific assessments because of socio-political reasons, not because she had amassed any evidence in her own favour. So we got down to brass tacks. I told her that I believed that the 'natural' way for humans was heterosexuality, and there was no 'gay gene'. She, thinking on her feet asked me "what is the heterosexual gene, then". I was thinking on my feet equally as quickly and I said "penises and vaginas are what denote or signify the existence of a biological trend or gene towards heterosexuality". This stumped her a bit and we had a few more exchanges and, once we got over the fact that I was not trying to make socio-political assessments based on my theory and was not suggesting supporting anti-gay legislation, I asked her how she would support her argument. She replied "I don't think there's any evidence either way, and I don't think that there's any way anyone can say or know either way." I couldn't let this one go because it came right out of page one in my "how to debate post modernist/subjectivist positions" book. The problem with that position that she suddenly took, or should I say, the problem with the CONTRAST of her TWO positions was that at first, she made an empirical statement that my theory wasn't true. Therefore she had an absolute statement about the fact of my position on homosexuality not being genetic. Homosexuality coming from childhood experience<>truth. This is an equally absolute statement as me saying Homosexuality coming from childhood experience=truth. So I called her on it. I told her that she can't hold both positions. That either she disagrees with me, and gives me her reasons for disagreeing- good, bad or indifferent. Or, she takes the position that there is no evidence either way, and can hold no definite disagreement or agreement with my theories and refuse to discuss it any further. I think she realized this when I called her on it and so the discussion pretty much ended there. I continued to think about it, however. I went back to the science of the issue. The genetics or non genetics of it. I thought about everything I knew about Darwinism. What was the essence of Charles Darwin's theory of evolution? It was the theory of evolution through natural selection. Now, normally when we think of natural selection, we describe it in terms of who or what has superior genes and therefore is more successful in getting its genes into the gene pool, where what doesn't adapt or mutate most favorably to its surroundings, doesn't breed. What is the single unique quality of homosexuals? They don't breed. They don't breed. Not because they're slower, less intelligent, or weaker- they don't breed because of preference. So what we have is a situation which in the description of evolution is actually reversed. If it were genetic, as my girlfriend suggests, then they have a genetic mutation which causes them to lose desire to breed with their biological opposites, without which, no new genes can be added to the gene pool. Instead of 'that which survives breeds', you have, in the case of the homosexual population, 'that which survives doesn't breed'. As a result, the world gay population should be shrinking. Now, it's going to be obvious that someone somewhere will argue that some gay people do breed because, fankly, some of them do. However, I would argue that that would require the homosexual population breed at a rate high enough to sustain a constant or growing number of homosexual genes in the gene pool. I would further argue that if the gay population is at 10% as has been suggested, that less then 50% of that 10% have bred or will breed. I would go further and suggest that probably less than 20% of that 10% will and are breeding. This is where I now need to get some education in genetics. I don't fully understand how genetics work, and thus may be wrong in that it only requires a tiny amount of the gene to be reentered into the stream of the species to maintain the population. For instance, if having the gene doesn't automatically make you homosexual, you would be of course, heterosexual. Therefore, the heterosexual population which carries the 'gay gene' could be bolstering the homosexual population through its own breeding. Any help and understanding on this issue, or more theories would be appreciated. From owner-chromosomes@net.bio.net Wed Mar 03 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!diablo.theplanet.net!news-lond.gip.net!news.gsl.net!gip.net!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail From: TopMan6304@aol.com Newsgroups: bionet.genome.chromosomes Subject: Serious? Date: 4 Mar 1999 03:43:59 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 115 Message-ID: <7bkvhv$hml$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk content-length: 4895 Return-Path: Apparently-To: TO REMOVE YOUR EMAIL ADDRESS, CALL 1 (800) 242-0363 #2155. --------------------------------------------------------------- IF YOU ARE SERIOUS ABOUT PROMOTING A PRODUCT, A SERVICE, A BUSINESS, OR A SITE ON THE NET, YOU NEED TO READ THIS MAILER! ================================================================== We offer an affordable range of unique softwares, services & products to help you to achieve your above objectives! ---------------------------------------------------------- 1)SOFTWARES: ___________ A)SENSOR PLUS!: a new & unique software that identifies a visitor to your site by detecting and grabbing the e-mail address of visitors to your site, and sending the visitors an email from you thanking them for the visit, and offering specials, etc. Try SENSOR PLUS! 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From owner-chromosomes@net.bio.net Sun Mar 07 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!wn4feed!worldnet.att.net!135.173.83.225!attworldnet!newsadm From: frank1492@worldnet.att.net (frank1492) Newsgroups: bionet.genome.chromosomes Subject: Eye Color Question Date: 8 Mar 1999 14:26:01 GMT Organization: AT&T WorldNet Services Lines: 4 Message-ID: <36e3ddd1.3794364@netnews.worldnet.att.net> Reply-To: frank1492@worldnet.att.net NNTP-Posting-Host: 12.79.222.212 X-Newsreader: Forte Free Agent 1.1/32.230 If both parents have blue eyes, MUST their children also have blue eyes? (Explanation also appreciated!) THank you!! Frank From owner-chromosomes@net.bio.net Sun Mar 07 22:00:00 1999 From: "SciMedWeb" Newsgroups: bionet.genome.chromosomes Subject: SciMedWeb news Date: Mon, 8 Mar 1999 20:41:33 +0100 Organization: EUnet Belgium, Leuven, Belgium Lines: 11 Message-ID: <7c19ta$a1n$13@news3.Belgium.EU.net> NNTP-Posting-Host: adial051.liege.eunet.be X-Newsreader: Microsoft Outlook Express 4.71.1712.3 X-MimeOLE: Produced By Microsoft MimeOLE V4.71.1712.3 Path: biosci!news.ic.sunysb.edu!news-nysernet-16.sprintlink.net!news-east1.sprintlink.net!-program!news-peer-europe.sprintlink.net!news.sprintlink.net!Sprint!news-feed.inet.tele.dk!bofh.vszbr.cz!newsfeed.tli.de!newsfeed.ecrc.net!newsrouter.chello.at!amsnews!news.tvd.be!news0.Belgium.EU.net!newsr.Belgium.EU.net!not-for-mail SciMedWeb, molecular aspects of breast cancer: http://www.geocities.com/HotSprings/Spa/3430/intro1.htm Breast cancer metastasis - Papers Nov-Dec 1998: http://www.geocities.com/HotSprings/Spa/3430/1998_6.htm Estrogen receptors and breast cancer - Papers Nov-Dec 1998: http://www.geocities.com/HotSprings/Spa/3430/er1998_6.htm Breast cancer and gene therapy - Papers 1998: http://www.geocities.com/HotSprings/Spa/3430/bcther98.htm From owner-chromosomes@net.bio.net Mon Mar 08 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!152.163.199.19!portc03.blue.aol.com!audrey01.news.aol.com!not-for-mail From: rcjohnsen@aol.com (Rcjohnsen) Newsgroups: bionet.genome.chromosomes Subject: Re: Eye Color Question Lines: 23 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 9 Mar 1999 01:37:21 GMT Organization: AOL http://www.aol.com References: <36e3ddd1.3794364@netnews.worldnet.att.net> Message-ID: <19990308203721.04004.00000174@ng02.aol.com> << If both parents have blue eyes, MUST their children also have blue eyes? (Explanation also appreciated!) THank you!! Frank >> NO! It is common for teachers talking about general inheritance patterns inn eye color to tell students that eye color is a single Mendelian factor-that brown wyw color is dominant to blue eye color. Hence most people believe that brown yed parents*BB X BB) will have all brown eyed children, that Bb X Bb will have 3 brown to one blue and that bb X bb blue X blue must have all blue eyed children. Eye color is not monogenic but inherited polygenetically ie. there are several different genes that contribute to eye color. The blue one sees depends upon very small granules in the iris which are coated with pigment(in the case of blue--not very much). Light is refoected back to the observer in the blue spectrum. As eyecolor becomes darker the granules become more numerous, larger and coated with more pigment. I have seen eyes that were violet, blue, greenish, yellowish, light hazel, brown, black, as I'm sure you have. I have know blue eyed couples with brown eyed children and as a brown eyed man I can assure you I had nothing to do with it. Enjoy, Roger From owner-chromosomes@net.bio.net Mon Mar 08 22:00:00 1999 Path: biosci!AOL.COM!SRock1158 From: SRock1158@AOL.COM Newsgroups: bionet.genome.chromosomes Subject: per request Date: 8 Mar 1999 23:22:19 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 35 Sender: daemon@net.bio.net Distribution: world Message-ID: <2c9a3237.36e4c66e@aol.com> NNTP-Posting-Host: net.bio.net INTERNATIONAL DRIVER'S LICENSE Need a new driver's license? Too many points or other trouble? Want a license that can never be suspended or revoked? Want ID for nightclubs or hotel check-in? Avoid tickets, fines, and mandatory driver's education. Protect your privacy, and hide your identity. The United Nations gave you the privilege to drive freely throughout the world! (Convention on International Road Traffic of September 19, 1949 & World Court Decision, The Hague, Netherlands, January 21, 1958) Take advantage of your rights. Order a valid International Driver's License that can never be suspended or revoked. Confidentiality assured. CALL NOW!!! 1-937-586-9313 From owner-chromosomes@net.bio.net Mon Mar 08 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news.maxwell.syr.edu!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail From: SRock1158@aol.com Newsgroups: bionet.genome.chromosomes Subject: per request Date: 9 Mar 1999 07:32:57 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 35 Message-ID: <7c2ir9$6qa$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk content-length: 697 Return-Path: Apparently-To: INTERNATIONAL DRIVER'S LICENSE Need a new driver's license? Too many points or other trouble? Want a license that can never be suspended or revoked? Want ID for nightclubs or hotel check-in? Avoid tickets, fines, and mandatory driver's education. Protect your privacy, and hide your identity. The United Nations gave you the privilege to drive freely throughout the world! (Convention on International Road Traffic of September 19, 1949 & World Court Decision, The Hague, Netherlands, January 21, 1958) Take advantage of your rights. Order a valid International Driver's License that can never be suspended or revoked. Confidentiality assured. CALL NOW!!! 1-937-586-9313 From owner-chromosomes@net.bio.net Tue Mar 09 22:00:00 1999 Path: biosci!news.stanford.edu!su-news-feed4.bbnplanet.com!su-news-hub1.bbnplanet.com!news.gtei.net!newsfeed.wli.net!portc04.blue.aol.com!audrey01.news.aol.com!not-for-mail From: rcjohnsen@aol.com (Rcjohnsen) Newsgroups: bionet.genome.chromosomes Subject: Re: gene formula? Lines: 17 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 10 Mar 1999 18:04:13 GMT Organization: AOL http://www.aol.com References: <36E69801.AD5C4263@hotmail.com> Message-ID: <19990310130413.19492.00000723@ng07.aol.com> << 1. What is the general unique molecular structure formula of a gene? 2. What is the reason for a specific mRNA molecule(coming from a specific gene or genes) to come to expression in a specific cel and not in a differend? How does this work on a molecule level? 3. >> etc. I recommend a good text on genetics like Suzuki (Genetic Analysis) or Lewin(Genes V or later). Rcjohnsen@aol.com From owner-chromosomes@net.bio.net Tue Mar 09 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!207.97.14.174!europa.clark.net!205.231.236.10!newspeer.monmouth.com!rill.news.pipex.net!pipex!newsfeed.amsterdam.nl.net!sun4nl!surfnet.nl!eur.nl!news.fgg.eur.nl!usenet From: Edward van Harskamp Newsgroups: bionet.genome.chromosomes Subject: gene formula? Date: Wed, 10 Mar 1999 17:04:17 +0100 Organization: University Hospital Rotterdam Lines: 29 Message-ID: <36E69801.AD5C4263@hotmail.com> NNTP-Posting-Host: gateway.azr.nl Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.05 [en] (Win95; I) 1. What is the general unique molecular structure formula of a gene? 2. What is the reason for a specific mRNA molecule(coming from a specific gene or genes) to come to expression in a specific cel and not in a differend? How does this work on a molecule level? 3. How does the translation of mRNA into a protein precisely work on a structural molecular level? 4. How does the gene proces of transcription and after that translation work on a structural molecular level? 5. How does the entire translation of mRNA molecule to the even-tually 3D molecular protein structure work? I already looked in the book called The Cell: A Molecular Approach and other books, but it was not advanced enough to round off the study project I am working on. If you have an answer to this question, please, mail this answer to EF_v_Harskamp@hotmail.com From owner-chromosomes@net.bio.net Tue Mar 09 22:00:00 1999 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.cwix.com!194.72.7.126!btnet-peer!btnet!news-lond.gip.net!news.gsl.net!gip.net!nntp.news.xara.net!xara.net!server6.netnews.ja.net!daresbury!not-for-mail From: "Karin.Metzlaff" Newsgroups: bionet.genome.chromosomes Subject: Phytosfere'99 Date: 10 Mar 1999 11:26:06 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 715 Message-ID: <7c5kse$58$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk Alternate-Recipient: allowed Original-To: biochrom@dl.ac.uk content-length: 51607 Disclose-Recipients: prohibited Return-Path: Auto-Forwarded: prohibited Importance: normal X-Dmw-Body-Names: C:\Karin\Phytosfereupdate2.doc Sensitivity: Company-Confidential --mw000000013A26371836E64C9B3FFC02027B00000028Fmw Content-Type: text/plain; charset="ISO-8859-1"; Type="Text"; name="Phytosfere_99_.TXT"; x-dmw-oid="2A864886F70F0301"; x-dmw-btname="PlainText" Dear Colleagues, please find attached the Phytosfere'99 programme and registration information. topics: Plant Biotech talks from Framework IV successes Panel Discussion on Plant Biotechnology Framework Programme V Science into Practice - start a company Speakers are top scientists, representatives from major European Companies, key persons from the EC(DGXII)and experts from Venture Capital/Finance. Journalists from at least 6 European countries are invited as rapporteurs. I am looking forward to see you there! Karin Metzlaff (AMICA & EPBN manager; http://www.epbn.de/announce/phytosfere99.html) --mw000000013A26371836E64C9B3FFC02027B00000028Fmw Content-Type: application/octet-stream; name="C:\Karin\Phytosfereupdate2.doc"; x-dmw-oid="2B0C02877305018339"; x-dmw-btname="MSWord97Doc" Content-Transfer-Encoding: base64 0M8R4KGxGuEAAAAAAAAAAAAAAAAAAAAAPgADAP7/CQAGAAAAAAAAAAAAAAABAAAAMAAAAAAA AAAAEAAARwAAAAEAAAD+////AAAAADEAAAD///////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// 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//////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////////////////////////////////////////////////////////////////// //////////8= --mw000000013A26371836E64C9B3FFC02027B00000028Fmw-- From owner-chromosomes@net.bio.net Tue Mar 09 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail From: FoxeTopp@aol.com Newsgroups: bionet.genome.chromosomes Subject: Strengthen your marrige or relationship Date: 10 Mar 1999 06:48:15 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 37 Message-ID: <7c54jf$kq0$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk content-length: 813 Return-Path: Apparently-To: ------------------------------------------------------------------------------ --------------------------- -Increase your sexual potential -Strengthen your marriage or relationship -Increase lust and romance -Better foreplay -Exercises anyone can do -Increase passion and desire -Be able to have sex more times a day -Satisfy your partners needs Its time to put futher enjoyment into your life, time is limited so use it to its full pleasure. Order our informational guide to Strengthen your marriage or relationship for our print value of $9.00. We will rush your guide to you within days of you receiving your payment. Ordering instructions are below. Order by mail send payment to: K.C. Smith 10 East Louisiana Evansville, IN 47711 Make sure to write your address twice to ensure delivery. From owner-chromosomes@net.bio.net Tue Mar 09 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!152.163.199.19!portc03.blue.aol.com!audrey01.news.aol.com!not-for-mail From: thevagirl@aol.com (The VAgirl) Newsgroups: bionet.genome.chromosomes Subject: genetic disorders Lines: 1 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 10 Mar 1999 20:55:09 GMT Organization: AOL http://www.aol.com Message-ID: <19990310155509.28644.00000649@ng126.aol.com> what is triple (xxx) mean ? what genetic disorder is this ? From owner-chromosomes@net.bio.net Wed Mar 10 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!205.252.116.205!howland.erols.net!portc02.blue.aol.com!audrey01.news.aol.com!not-for-mail From: rcjohnsen@aol.com (Rcjohnsen) Newsgroups: bionet.genome.chromosomes Subject: Re: genetic disorders Lines: 9 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 11 Mar 1999 21:00:03 GMT Organization: AOL http://www.aol.com References: <19990310155509.28644.00000649@ng126.aol.com> Message-ID: <19990311160003.06380.00001184@ng-fz1.aol.com> << what is triple (xxx) mean ? what genetic disorder is this ? >> To my knowledge, it is simply known as triplo-X syndrome which most often are normal females in appearance and many are married with children who are generally normal chromosomally. I assume you're referring to humans, but triple XXX refers to anything with 3 X's. I can't be more specific unless you are. From owner-chromosomes@net.bio.net Thu Mar 11 22:00:00 1999 Path: biosci!health.adelaide.edu.au!gkremmid From: gkremmid@health.adelaide.edu.au (Gabriel Kremmidiotis) Newsgroups: bionet.genome.chromosomes Subject: overlaping genes Date: 11 Mar 1999 18:21:20 -0800 Organization: WCH - Cytogenetics Lines: 30 Sender: daemon@net.bio.net Distribution: world Message-ID: <36E8784A.973F522D@pulse.adelaide.edu.au> NNTP-Posting-Host: net.bio.net Hi all, Can anyone supply an example (with reference if possible) of overlaping genes transcribed in the same direction, in higher eukaryotic genomes? Thanks. Gabriel -- \\|// (o o) C e n t r o m e r e -. .-. .-oOOo~(_)~oOOo-. .-. .-. .-. .-. ||X|||\ /|||X|||\ /|||X|||\ /|||X|||\ /|||X|||\ |/ \|||X|||/ \|||X|||/ \|||X|||/ \|||X|||/ \|||X ' `-' `-' `-' `-' `-' `-' `-' `-' `-' Dr Gabriel Kremmidiotis Department of Cytogenetics & Molecular Genetics Women's & Children's Hospital 72 King William Rd North Adelaide SA 5006 Australia From owner-chromosomes@net.bio.net Sat Mar 13 22:00:00 1999 Path: biosci!rutgers!gatech!cpk-news-hub1.bbnplanet.com!news.gtei.net!news1.bellglobal.com!198.235.216.4.POSTED!not-for-mail From: shyqnj@fakeaddressforyourlist.com Newsgroups: taos.forsale,bionet.genome.chromosomes,su.class.me217c,alt.tv.melrose-place Subject: $6 INTO THOUSANDS! 6800 [1/2] Lines: 3 Message-ID: Date: Sun, 14 Mar 1999 08:10:00 GMT NNTP-Posting-Host: 209.226.55.170 X-Trace: 198.235.216.4 921399000 209.226.55.170 (Sun, 14 Mar 1999 03:10:00 EDT) NNTP-Posting-Date: Sun, 14 Mar 1999 03:10:00 EDT Organization: Bell Solutions CHECK OTHER POSTING FOR MESSAGE! revdfkbzqfiiejbubxxupewzuzcptmeesptlbpgtvzvfjhrqevqiuwsovwlnxcvqckbyljdx From owner-chromosomes@net.bio.net Sun Mar 14 22:00:00 1999 Path: biosci!cnn.nas.nasa.gov!newsfeed.berkeley.edu!news.maxwell.syr.edu!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail From: WToler5973@aol.com Newsgroups: bionet.genome.chromosomes Subject: MAIL ORDER KNOW HOW! 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BOX 7247 GARDEN CITY, NY 11530 U.S.A From owner-chromosomes@net.bio.net Sun Mar 14 22:00:00 1999 From: Daniel =?iso-8859-1?Q?Schr=F6der?= Newsgroups: bionet.genome.chromosomes Subject: searching for information about down syndrom Date: Mon, 15 Mar 1999 21:38:57 +0000 Organization: BITEL GmbH Lines: 7 Message-ID: <36ED7DF1.229F13EC@Bitel.net> NNTP-Posting-Host: 62.144.119.186 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.5 [de]C-CCK-MCD QXW03207 (Win98; I) X-Accept-Language: de,sv,en Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.cwix.com!205.252.116.205!howland.erols.net!panix!yellow.newsread.com!netaxs.com!newsread.com!uunet!ffx.uu.net!in1.uu.net!news.planetc.com!news.bicos.de!news.bitel.net!usenet Hello! I'm searching for information about Trisomie21 / Down Syndrom. Please send info or links to: DS@Bitel.net Thanks before From owner-chromosomes@net.bio.net Mon Mar 15 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!207.97.14.174!europa.clark.net!205.252.116.205!howland.erols.net!portc02.blue.aol.com!audrey01.news.aol.com!not-for-mail From: liplollie@aol.com (Liplollie) Newsgroups: bionet.genome.chromosomes Subject: question abt chromosome 9 Lines: 18 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 16 Mar 1999 12:47:41 GMT Organization: AOL http://www.aol.com Message-ID: <19990316074741.01637.00000010@ng-fv1.aol.com> I dont know if anyone in this newsgroup will be ablt to help me out here, but I have a question dealing with Chromosomes...... My friend just had a baby about 3 weeks ago and the pediatrician that saw the baby in the hospital wanted to test the baby for Downs Syndrome. The test results came back yesterday and it has been determined that the baby does not have downs syndrome but the doctor has referred my friend to go to genetic counseling because the test that they ran came back abnormal. He said that there is something wrong with the baby's chromosome # 9. What does this mean? I don't have any idea how this chromosome thing works....does this mean that the baby has some kind of a disorder? If so , then what could possibly be wrong with her? The doctor didnt go into detail as to what could be wrong, he just said that there was something wrong with the chromosome. Any help here would be great Thank you.... Kim Hendricks From owner-chromosomes@net.bio.net Tue Mar 16 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!192.26.210.166!sunqbc.risq.qc.ca!carnaval.risq.qc.ca.POSTED!not-for-mail Message-ID: <36F01CC5.C4F7B077@agora.ulaval.ca> From: Tahar aboulkassim X-Mailer: Mozilla 4.05 [en] (WinNT; I) MIME-Version: 1.0 Newsgroups: bionet.molbio,bionet.biology,bionet.cellbiol,bionet.molbio.methds-reagnts,bionet.molbio.oncogenes,bionet.genome.chromosomes,abh346@agora.ulaval.ca Subject: Northern blot problem(s) Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit Lines: 27 Date: Wed, 17 Mar 1999 21:18:16 GMT NNTP-Posting-Host: 132.203.232.7 X-Complaints-To: abuse@ulaval.ca X-Trace: carnaval.risq.qc.ca 921705496 132.203.232.7 (Wed, 17 Mar 1999 16:18:16 EDT) NNTP-Posting-Date: Wed, 17 Mar 1999 16:18:16 EDT Xref: biosci bionet.cellbiol:11500 bionet.molbio.methds-reagnts:74849 bionet.genome.chromosomes:2351 Hi, There, I have always a problem when I do my northern blot experience. The problem is the non-specific hybridization of my probes with 28S and 18S and I have a strong signal for these RNAs. furthermore, the specific signal is either weak or absent. I have changed many parameters in order to improve or to resolve this problem. But, always have the same problem. It is suspected that the blocking agents may be the source of the problem, I then used other blocking agents like poly A+, with those used previously e.g. Salmon sperm DNA (Gibco), and Denhardt solution. We used several different probes ( DNA and RNA probes) and conditions of prehybridization/hybridization : 60°C for RNA probe and 42° for DNA probe (with formamide), but the result remained the same. I would be grateful if someone can give me an idea ( may be someone had already the same problem) of what could be the problem. Thank you M. Taha Aboulkassim Onco-urological laboratory Cancer Research Center Laval university Quebec (Canada) E-mail : abh346@agora.ulaval.ca From owner-chromosomes@net.bio.net Tue Mar 16 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.atl!upstream.atl!news2.mia.POSTED!not-for-mail Message-ID: <36F020EF.998F4C38@bellsouth.net> From: Waldo Ramos X-Mailer: Mozilla 4.04 [en]C-bls40 (Win95; U) MIME-Version: 1.0 Newsgroups: bionet.genome.chromosomes Subject: I HOPE YOU UNDERSTAND MY EXPLANATION Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit Lines: 9 Date: Wed, 17 Mar 1999 21:39:08 GMT NNTP-Posting-Host: host-209-214-3-121.mia.bellsouth.net NNTP-Posting-Date: Wed, 17 Mar 1999 16:39:08 EST FIRST OF ALL BLUE IS A RECESSIVE GENE.FOR A PERSON TO HAVE BLUE EYES HE MUST HAVE A PAIR OF BLUE (HOMOZYGOUS RECESSIVE GENE).THE DAD HAS TO HAVE ALL HIS GENES, RELATED TO THE EYECOLOR, BLUE.SO THAT MEANS IF THEY BOTH HAVE BLUE EYES THEY CAN ONLY SEND BLUE INFORMATION. YSE THEIR CHILDREN MUST HAVE BLUE EYES From owner-chromosomes@net.bio.net Wed Mar 17 22:00:00 1999 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.cwix.com!195.252.142.5!newsfeed.tli.de!newsfeed.nacamar.de!dispose.news.demon.net!demon!news.demon.co.uk!demon!deadline-comms.demon.co.uk!none444.yet From: no.email.address.entered@none444.yet Newsgroups: bionet.genome.chromosomes Subject: URGENT! WINTESLA NEEDED SOFTWARE FOR NOKIA MOBILE PHONES URGENT! Date: Thursday, 18 Mar 1999 20:26:10 -0600 Organization: Message-ID: <18039920.2610@none444.yet> Reply-To: wintesla@deadline-comms.demon.co.uk NNTP-Posting-Host: deadline-comms.demon.co.uk X-NNTP-Posting-Host: deadline-comms.demon.co.uk:194.222.222.150 X-Trace: news.demon.co.uk 921788918 nnrp-06:28239 NO-IDENT deadline-comms.demon.co.uk:194.222.222.150 X-Complaints-To: abuse@demon.net Lines: 8 Hi I'm looking for wintesla the software needed to change the firmware if you have seen such software please post it to this address or a URL for it wintesla@deadline-comms.demon.co.uk Thanx Wayne From owner-chromosomes@net.bio.net Thu Mar 18 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!207.97.14.174!europa.clark.net!194.162.162.196!newsfeed.nacamar.de!newsfeed.nacamar.de!unlisys!news.snafu.de!fu-berlin.de!news.ruhrgebiet.individual.net!news-koe1.dfn.de!uni-muenster.de!ASTERIX.UNI-MUENSTER.DE!hohoff From: "Carsten Hohoff" Newsgroups: bionet.genome.chromosomes Subject: double signal in chromos. FISH ? Date: Fri, 19 Mar 1999 13:34:13 +0100 Organization: Westfaelische Wilhelms-Universitaet Muenster, Germany Lines: 13 Sender: "Carsten Hohoff" Message-ID: NNTP-Posting-Host: asterix.uni-muenster.de Mime-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII Dear experts in the field of chromosomal FISHing ! I expected a double-signal on metaphase chromosomes (due to the occurrence of the gene on both chromatides) - but what I observe in nearly half of the chromosomes inspected is that there is just ONE fluorescence signal ! What may be the reason ? Is the chromatide DNA not denatured well enough ? Any helpful comment is appreciated Carsten Hohoff From owner-chromosomes@net.bio.net Thu Mar 18 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news.maxwell.syr.edu!news.eecs.umich.edu!news.bu.edu!dip15-ppp-222.bu.edu!user From: gilbride@bu.edu (kevin gilbride) Newsgroups: bionet.genome.chromosomes Subject: South of Boston Date: Thu, 18 Mar 1999 21:12:58 -0500 Organization: b.u. Lines: 4 Message-ID: NNTP-Posting-Host: dip15-ppp-222.bu.edu Bench scientist with over nine years of protein biochemistry and molecular biology experience seeks ground floor oportunity with genomics or diagnostic lab south of Boston. For more information email gilbride@bu.edu From owner-chromosomes@net.bio.net Thu Mar 18 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!128.230.129.106!news.maxwell.syr.edu!howland.erols.net!portc02.blue.aol.com!audrey01.news.aol.com!not-for-mail From: rcjohnsen@aol.com (Rcjohnsen) Newsgroups: bionet.genome.chromosomes Subject: Re: question abt chromosome 9 Lines: 7 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 19 Mar 1999 15:32:38 GMT Organization: AOL http://www.aol.com References: <19990316074741.01637.00000010@ng-fv1.aol.com> Message-ID: <19990319103238.15198.00000403@ng144.aol.com> << I dont know if anyone in this newsgroup will be ablt to help me out here, but I have a question dealing with Chromosomes...... >> The onus is on the doctor to explain the anomaly in detail or refer the parents to the cytogeneticist that did the test. From owner-chromosomes@net.bio.net Sun Mar 21 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!152.163.199.19!portc03.blue.aol.com!audrey01.news.aol.com!not-for-mail From: jsmith2743@aol.com (JSmith2743) Newsgroups: bionet.genome.chromosomes Subject: chromosomal disorders Lines: 1 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 22 Mar 1999 04:26:21 GMT Organization: AOL http://www.aol.com Message-ID: <19990321232621.08202.00000233@ng-cf1.aol.com> what does xyy mean, what kind of disorder is this? From owner-chromosomes@net.bio.net Wed Mar 24 22:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!128.230.129.106!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail From: baron0805@aol.com (Baron0805) Newsgroups: bionet.genome.chromosomes Subject: Re: question abt chromosome 9 Lines: 7 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 25 Mar 1999 15:41:35 GMT Organization: AOL http://www.aol.com References: <19990316074741.01637.00000010@ng-fv1.aol.com> Message-ID: <19990325104135.16375.00000084@ng140.aol.com> Did they say what exactly was wrong with chromosome number 9? There could be what the call a trisomy. There could also be structural damage. Find that out and let me know. Meanwhile, I will try to find problems associated with chromosome 9. Baron. Question everything!!!! From owner-chromosomes@net.bio.net Wed Mar 24 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.stanford.edu!news-feed.inet.tele.dk!bofh.vszbr.cz!newsfeed.wli.net!portc04.blue.aol.com!audrey01.news.aol.com!not-for-mail From: baron0805@aol.com (Baron0805) Newsgroups: bionet.genome.chromosomes Subject: Re: chromosomal disorders Lines: 4 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 25 Mar 1999 15:07:00 GMT Organization: AOL http://www.aol.com References: <19990321232621.08202.00000233@ng-cf1.aol.com> Message-ID: <19990325100700.16375.00000059@ng140.aol.com> If I am right (undergrad), this is what they call a supermale. It is a genotype in which a cell undergoes meiosis and receives an extra y chromosome. If I am wrong, let me know. Question everything!!!! From owner-chromosomes@net.bio.net Fri Mar 26 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.stanford.edu!news-feed.inet.tele.dk!bofh.vszbr.cz!newsfeed.gamma.ru!Gamma.RU!nntpgate.globalserve.net!news.globalserve.net!not-for-mail From: "Donald Cameron" Newsgroups: bionet.genome.chromosomes Subject: chromosome 12 disorder Date: Sat, 27 Mar 1999 13:36:26 -0600 Organization: Globalserve Communications Inc. Lines: 6 Message-ID: <7dj8li$i5e$1@whisper.globalserve.net> NNTP-Posting-Host: dialin156.hamilton.globalserve.net X-Trace: whisper.globalserve.net 922559986 18606 209.90.138.219 (27 Mar 1999 18:39:46 GMT) X-Complaints-To: abuse@globalserve.net NNTP-Posting-Date: 27 Mar 1999 18:39:46 GMT X-Newsreader: Microsoft Outlook Express 4.72.3110.5 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 I am looking for information about living with someone who suffers from chromosome 12 disorder. Any help you can provide will be appreciated From owner-chromosomes@net.bio.net Fri Mar 26 22:00:00 1999 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.genome.chromosomes Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 27 Mar 1999 02:00:14 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 233 Sender: daemon@net.bio.net Distribution: world Message-ID: <199903271000.CAA25741@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-chromosomes@net.bio.net Sat Mar 27 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.stanford.edu!news-feed.inet.tele.dk!bofh.vszbr.cz!eyre.news.pipex.net!pipex!bore.news.pipex.net!pipex!not-for-mail From: "RossB" Newsgroups: bionet.genome.chromosomes Subject: Deletion in chromosome 10. Date: Sun, 28 Mar 1999 19:37:38 +0100 Organization: UUNET WorldCom server (post doesn't reflect views of UUNET WorldCom) Lines: 31 Message-ID: <7dlt89$3uv$1@plug.news.pipex.net> NNTP-Posting-Host: userc661.uk.uudial.com X-Newsreader: Microsoft Outlook Express 4.71.1712.3 X-MimeOLE: Produced By Microsoft MimeOLE V4.71.1712.3 Dear all, Our 2 year old daughter has recently been diagnosed as having a disorder of chromosome 10 specifically.... monosomy at 10p15 -> pter and trisomy 10q26.1 -> qter. The results were obtained using the F.I.S.H technique. We are aware of Cri Du Chat syndrome that affects chromosome 5, as this is what the doctor originally thought she may have. However once the cytogenetic tests were returned it has turned out that she has the deletion / duplication anomaly described above. I understand that some of the symptoms/affects of this will be the same as in all deletion syndromes(possible developmental delays etc) but we are trying to gain a more in depth understanding of the short and long term effects that it may have on her. We are awaiting results of blood test also, to see if this was passed down genetically. We can find very little about syndromes relating to chromosome 10 so any advice,information or pointers to good reference sources would be appreciated. Many Thanks, Ross Email : 400tech@msn.com From owner-chromosomes@net.bio.net Sat Mar 27 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail From: liplollie@aol.com (Liplollie) Newsgroups: bionet.genome.chromosomes Subject: Re: question abt chromosome 9 Lines: 3 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 28 Mar 1999 04:54:40 GMT Organization: AOL http://www.aol.com References: <19990325104135.16375.00000084@ng140.aol.com> Message-ID: <19990327235440.26299.00000279@ng67.aol.com> No not yet, the doctor said that he didn't know and that my friend has to go to genetic counseling but their appointment isn't until May 23, we kind of didn't want to have to wait that long..... thanks for your help From owner-chromosomes@net.bio.net Mon Mar 29 23:00:00 1999 From: "jiajun" Newsgroups: bionet.genome.chromosomes References: <36C9ADD0.FAC43113@rdg.ac.uk> Subject: Re: university project Date: Tue, 30 Mar 1999 13:09:57 +0800 Lines: 4 X-Newsreader: Microsoft Outlook Express 4.72.3115.0 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 NNTP-Posting-Host: 203.116.129.49 Message-ID: <3700d687.0@news.cyberway.com.sg> Path: biosci!pravda.ucr.edu!awabi.library.ucla.edu!128.230.129.106!news.maxwell.syr.edu!news-peer1.sprintlink.net!news-in-west1.sprintlink.net!news.sprintlink.net!news1.kddnet.ad.jp!newsvr.cyberway.com.sg!news.cyberway.com.sg!203.116.129.49 This site may help you www.carbon.wi.mit.edu From owner-chromosomes@net.bio.net Mon Mar 29 23:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!sunqbc.risq.qc.ca!torn!resunix.sickkids.on.ca!not-for-mail From: Abdellah Djebli Newsgroups: bionet.genome.chromosomes Subject: A new WWW accessible Bioinformatics Centre..the BSC Date: Mon, 29 Mar 1999 16:50:40 -0500 Organization: Hospital for Sick Children Lines: 40 Message-ID: <36FFF5B0.E30E8DB0@sickkids.on.ca> Reply-To: help@bioinfo.sickkids.on.ca NNTP-Posting-Host: 142.20.134.90 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.5 [en] (WinNT; U) X-Accept-Language: en The BSC (Bioinformatics Supercomputing Centre) has been established at the Hospital for Sick Children in Toronto, Ontario, Canada. The BSC has recently acquired Canada's most powerful supercomputer devoted to biological and bioinformatics research. In addition to offering the online resources listed below, the BSC provides assistance for bioinformatics programs, databases etc. Contact us (see below) for support. The BSC's Mission: To be the Canadian leader in bioinformatics through innovative computational research and provision of training, support, software, and database access. Currently, the BSC provides, free of charge, the following internet accessible resources to scientists: 1) High-speed BLAST of the most current databases on the Origin 2000 supercomputer (SGI) 2) Canadian Node of the human Genome Data Base (GDB) 3) The Cystic Fibrosis Mutation Database 4) Software enhancement/creation 5) Bioinformatics Training/Data analysis 6) The GCG package and its new web interface--SeqWeb, available to researchers within the Hospital for Sick Children Visit our website http://www.bioinfo.sickkids.on.ca Call our Help Desk at (416) 813-8877 E-mail help@bioinfo.sickkids.on.ca Brenda Muskat, Analyst/Trainer Bioinformatics Supercomputing Centre Hospital for Sick Children 555 University Ave. Elm 10-104 Toronto, Ontario M5G 1X8 From owner-chromosomes@net.bio.net Mon Mar 29 23:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!128.230.129.106!news.maxwell.syr.edu!howland.erols.net!portc02.blue.aol.com!audrey01.news.aol.com!not-for-mail From: demian999@aol.com (Demian999) Newsgroups: bionet.genome.chromosomes Subject: NEED INFO ON CHROMOSOMES 4,6,13,15 and 18 Lines: 8 NNTP-Posting-Host: ladder05.news.aol.com X-Admin: news@aol.com Date: 30 Mar 1999 22:01:10 GMT Organization: AOL http://www.aol.com Message-ID: <19990330170110.13184.00000125@ng-ce1.aol.com> I am currently doing a paper on Bipolar Disorder and I have discovered that the gene for that disease is thought to be found on Chromosomes 4, 6, 13, 15 and 18. The only problem i am facing is the fact that I can't find a site or anyone that can tell me what those Chromosomes are for. My paper is due tomorrow<3/31> and i am panicing...PLEASE HELP!!! Sincerely, Jayson From owner-chromosomes@net.bio.net Mon Mar 29 23:00:00 1999 From: "jiajun" Newsgroups: bionet.genome.chromosomes References: <36ED7DF1.229F13EC@Bitel.net> Subject: Re: searching for information about down syndrom Date: Tue, 30 Mar 1999 21:55:16 +0800 Lines: 12 X-Newsreader: Microsoft Outlook Express 4.72.3115.0 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 NNTP-Posting-Host: 203.116.129.49 Message-ID: <3700d688.0@news.cyberway.com.sg> Path: biosci!agate!newsfeed.berkeley.edu!news-peer1.sprintlink.net!news-in-west1.sprintlink.net!news.sprintlink.net!news1.kddnet.ad.jp!newsvr.cyberway.com.sg!news.cyberway.com.sg!203.116.129.49 Down's Syndrome is caused by having an additional copy of the chromosome 21 meaning the child has three copies of the chromosome 21, this will result in the child having varying degrees of mental retardation, heart defects, a short stocky body, characteristic eye folds and lack of muscle tone. This genetic abnormality can be detected in an unborn foetus if it is afflicted, it is usually prudent to abort the foetus under such circumstances. The probability of such a defect occurring increases with the age of the mother, especially after the age of 35. From owner-chromosomes@net.bio.net Tue Mar 30 23:00:00 1999 Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!207.97.14.174!europa.clark.net!207.114.4.11!nntp.abs.net!newshub2.home.com!newshub1.home.com!news.home.com!news.rdc1.ab.wave.home.com.POSTED!not-for-mail From: "Colin McLellan" Newsgroups: bionet.genome.chromosomes Subject: Meiosis in cells with Trisomy Lines: 12 X-Priority: 3 X-MSMail-Priority: Normal X-Newsreader: Microsoft Outlook Express 5.00.2014.211 X-MimeOLE: Produced By Microsoft MimeOLE V5.00.2014.211 Message-ID: <3ihM2.12546$2t5.23206@news.rdc1.ab.wave.home.com> Date: Wed, 31 Mar 1999 04:13:51 GMT NNTP-Posting-Host: 24.65.146.11 X-Complaints-To: abuse@home.net X-Trace: news.rdc1.ab.wave.home.com 922853631 24.65.146.11 (Tue, 30 Mar 1999 20:13:51 PDT) NNTP-Posting-Date: Tue, 30 Mar 1999 20:13:51 PDT Organization: @Home Network Canada I was wondering if anyone can tell me what occurs when a cell with trisomy undergoes meiosis. Does the extra chromosome prevent this entirely when it cannot form a tetrad in meiosis I, or does it split as in mitosis with only a single chromatid going to the daughter cells? Specifically, this is in reference to the production of gametes in humans with Down's syndrome (trosomy 21). Thank you in advance... Colin