From owner-chromosomes@net.bio.net Thu Apr 01 23:00:00 1999
Path: biosci!UCRAC1.UCR.EDU!judelson
From: judelson@UCRAC1.UCR.EDU ("Howard S. Judelson")
Newsgroups: bionet.genome.chromosomes
Subject: Postdoc positions, Phytophthora ESTs/functional genomics,
 Riverside USA
Date: 2 Apr 1999 11:48:53 -0800
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POSTDOCTORAL POSITIONS AVAILABLE

Functional genomics/molecular genetics
of Phytophthora infestans

Postdoctoral associates are sought to study Phytophthora infestans, the
oomycete fungus that causes the late blight diseases of potato and tomato.
P. infestans is one of the world's most important plant pathogens, with a
direct economic impact exceeding $5 billion per year.

The successful applicants will join projects aimed at identifying and
characterizing genes important in the growth and development of P.
infestans, with an emphasis on sexual and asexual sporulation.  The
projects involve constructing cDNA libraries; identifying genes of interest
from an EST catalogue and an expression profiling database (for example,
microarrays); and characterizing the regulation and function of genes by
manipulating their expression in P. infestans transformants and other
strategies.  Funding for these positions are available for up to 3 years.

The laboratory is located at the Riverside campus of the University of
California, which is situated in a dynamic region of southern California.
Additional information about the laboratory is available at
http://cnas.ucr.edu/~ppath/faculty/hj.html.

Applicants must have a Ph.D. in a relevant discipline and demonstrated
skill in cDNA library construction and/or gene analysis techniques.
Experience with filamentous fungi is NOT required and scientists with
training in other systems (plants, etc.) are encouraged to apply.

To apply, send a curriculum vitae and the names of three references
(including addresses and telephone numbers) to the addresses shown below.
Please label any email attachments with the author's last name!

Dr. Howard Judelson
Department of Plant Pathology
University of California
Riverside, California 92521 USA
email: judelson@ucrac1.ucr.edu
fax: 909-787-4294




From owner-chromosomes@net.bio.net Sat Apr 03 23:00:00 1999
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"giroire.ch" wrote:
> 
> je recherche des renseignements clairs et comprehensibles pour un non
> medecin sur le chromosome 14.
> quel est son role et quelle anomalie peut  il engendrer chez le foetus.
> 
>                                                    merci d'avance
> 
> christophe

deficiencies (diseases) associated with chromosome 14 can be found
on the OMIM site:

http://www.ncbi.nlm.nih.gov/Omim/

Also look at "genes and disease" for a layperson's view of some of 
diseases in humans:

http://www.ncbi.nlm.nih.gov/disease/

But these pages are much less comprehensive than OMIM: 
currenly only 60 "pages" or documents in "Genes and disease" 
and more than 10,000 in OMIM. I'm told more are on the way though.

Hope this helps,

francis

--                                                                 
| B.F. Francis Ouellette                     tel: (604) 875-3815  |
| Director, Bioinformatics Core Facility     fax: (604) 875-3800  |
| Centre for Molecular Medicine and Therapeutics, UBC, Canada     |
| francis@cmmt.ubc.ca                     http://www.cmmt.ubc.ca  |
                                                                   
Canadian Bioinformatics Workshop Series:                           
                             http://www.cmmt.ubc.ca/bioinformatics/

From owner-chromosomes@net.bio.net Sat Apr 03 23:00:00 1999
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From: "giroire.ch" <giroire.ch@infonie.fr>
Newsgroups: bionet.genome.chromosomes
Subject: chromosome 14
Date: Sun, 4 Apr 1999 19:21:15 +0100
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je recherche des renseignements clairs et comprehensibles pour un non
medecin sur le chromosome 14.
quel est son role et quelle anomalie peut  il engendrer chez le foetus.

                                                   merci d'avance

christophe



From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
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From: "Colin McLellan" <colin14@home.com>
Newsgroups: bionet.genome.chromosomes
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giroire.ch:  Si vous ne comprenez pas l'anglais, je peux traduire.


a3a55093 <Francis_Ouellette@bc.sympatico.ca> wrote in message
news:37079A73.AC38504C@bc.sympatico.ca...
>
>
> "giroire.ch" wrote:
> >
> > je recherche des renseignements clairs et comprehensibles pour un non
> > medecin sur le chromosome 14.
> > quel est son role et quelle anomalie peut  il engendrer chez le foetus.
> >
> >                                                    merci d'avance
> >
> > christophe
>
> deficiencies (diseases) associated with chromosome 14 can be found
> on the OMIM site:
>
> http://www.ncbi.nlm.nih.gov/Omim/
>
> Also look at "genes and disease" for a layperson's view of some of
> diseases in humans:
>
> http://www.ncbi.nlm.nih.gov/disease/
>
> But these pages are much less comprehensive than OMIM:
> currenly only 60 "pages" or documents in "Genes and disease"
> and more than 10,000 in OMIM. I'm told more are on the way though.
>
> Hope this helps,
>
> francis
>
> --
> | B.F. Francis Ouellette                     tel: (604) 875-3815  |
> | Director, Bioinformatics Core Facility     fax: (604) 875-3800  |
> | Centre for Molecular Medicine and Therapeutics, UBC, Canada     |
> | francis@cmmt.ubc.ca                     http://www.cmmt.ubc.ca  |
>
> Canadian Bioinformatics Workshop Series:
>                              http://www.cmmt.ubc.ca/bioinformatics/



From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
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From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: chromosomal disorders 
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<< what does xyy mean, what kind of disorder is this?
 >>
XYY are males with two Y chromosomea and a single X as opposed to normal XY
males.
Rcjohnsen@aol.com

From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
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From: spice-girls@tmp.net
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From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
Path: biosci!SILVA.TAMU.EDU!jvb
From: jvb@SILVA.TAMU.EDU ("Dr. van Buijtenen")
Newsgroups: bionet.genome.chromosomes
Subject: Re: Info on chromosomes in general, esp. meiosis
Date: 5 Apr 1999 10:32:46 -0700
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On Mon, 5 Apr 1999, Stephanie wrote:

> Hello,
> I'm Stephanie (13)
> 
> I am trying to plan, over my Easter holidays, a system for introducing
> diploid cell (Is that the right term? I mean the possibility of
> recessive genes, so double the DNA.)  into an artificial life game I
> play. I keep coming up against a major stumbling block: chromosomes.
> 
> I especially want to clear up these points (I will try to get all the
> terms right):
> Do chromosomes carry dominant/recessive forms of the same gene (alleles)
> together on one chromosome, or are they carried on different chromosomes
> and the chromosomes 'pair up'?

Different alleles at the same locus are carried on different chromosomes.
They do pair up.


> 
> If they don't pair up, why does colour blindness affect males
> predominantly?
> 

The gene for color blindness is located on the X chromosome. Since males
have only one X chromosome it will always be expressed in the male if it
is present. 

> What exactly are chromatids, and why do we need them?
> 
> What are double-stranded chromosomes, and why do we need them?
> 
Good questions. I learned my cytology and DNA chemistry about 40 years
apart so I may be connecting them wrong. DNA is naturally double stranded.
The two strands are not identical, but complementary. The cell can
reconstruct double stranded DNA from either single strand. I expect a
single strand corresponds to a chromatid (a cytological term), but I am
not sure of that.

> Why, before a cell is about to undergo meiosis, does it have twice the
> genetic information in a normal cell, when, if it had half, it could
> just divide straight away?

I think your question is based on some wrong assumptions. For all
practical purposes all diploid cells have the same genetic information,
and they can divide any time via mitotic division. 

> 
> What is the point of crossover? Does it give an evolutionary advantage,
> or is it just a side effect?
> 
Crossing over recombines different mutations does giving rise to many new
combinations. This pool of variation is the raw material that natural
selection works on. Evolution would be much slower without recombination.



> I would be very grateful if anyone could give up a few minutes of their
> time to answer some of these questions for me.
> 
> Thanks,
> 
> Stephanie
> 
> 
> opes this helps. J. P. van Buijtenen


From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
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From: Stephanie <steffik@the-funny-farm.freeserve.co.uk>
Newsgroups: bionet.genome.chromosomes
Subject: Info on chromosomes in general, esp. meiosis
Date: Mon, 05 Apr 1999 09:30:23 +0100
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Hello,
I'm Stephanie (13)

I am trying to plan, over my Easter holidays, a system for introducing
diploid cell (Is that the right term? I mean the possibility of
recessive genes, so double the DNA.)  into an artificial life game I
play. I keep coming up against a major stumbling block: chromosomes.

I especially want to clear up these points (I will try to get all the
terms right):
Do chromosomes carry dominant/recessive forms of the same gene (alleles)
together on one chromosome, or are they carried on different chromosomes
and the chromosomes 'pair up'?

If they don't pair up, why does colour blindness affect males
predominantly?

What exactly are chromatids, and why do we need them?

What are double-stranded chromosomes, and why do we need them?

Why, before a cell is about to undergo meiosis, does it have twice the
genetic information in a normal cell, when, if it had half, it could
just divide straight away?

What is the point of crossover? Does it give an evolutionary advantage,
or is it just a side effect?

I would be very grateful if anyone could give up a few minutes of their
time to answer some of these questions for me.

Thanks,

Stephanie



From owner-chromosomes@net.bio.net Sun Apr 04 23:00:00 1999
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From: "Colin McLellan" <colin14@home.com>
Newsgroups: bionet.genome.chromosomes
References: <19990321232621.08202.00000233@ng-cf1.aol.com> <19990404211231.20409.00002126@ng-fr1.aol.com>
Subject: Re: chromosomal disorders 
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Individuals with this disorder is commonly referred to as "supermales."
They are often tall and larger than normal, however they develop primary and
secondary sex characteristics normally, and are usually fertile.

i'm not an expert, but this is what my notes say

Rcjohnsen <rcjohnsen@aol.com> wrote in message
news:19990404211231.20409.00002126@ng-fr1.aol.com...
> << what does xyy mean, what kind of disorder is this?
>  >>
> XYY are males with two Y chromosomea and a single X as opposed to normal
XY
> males.
> Rcjohnsen@aol.com



From owner-chromosomes@net.bio.net Mon Apr 05 23:00:00 1999
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From: illegal@tmp.net
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Subject: ILLEGAL SPICE GIRLS PICS !!! 25919
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From owner-chromosomes@net.bio.net Mon Apr 05 23:00:00 1999
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From: Aoife McLysaght <amclysag@tcd.ie>
Newsgroups: bionet.genome.chromosomes
Subject: Re: Info on chromosomes in general, esp. meiosis
Date: Tue, 06 Apr 1999 18:18:46 +0100
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> Hello,
> I'm Stephanie (13)
>
> I am trying to plan, over my Easter holidays, a system for introducing
> diploid cell (Is that the right term? I mean the possibility of
> recessive genes, so double the DNA.)  into an artificial life game I
> play. I keep coming up against a major stumbling block: chromosomes.
>
> I especially want to clear up these points (I will try to get all the
> terms right):
> Do chromosomes carry dominant/recessive forms of the same gene (alleles)
> together on one chromosome, or are they carried on different chromosomes
> and the chromosomes 'pair up'?

Everybody has two of every chromosome type (types are numbered 1-22 and then
the sex chromosomes X and Y). Each chromosome type consists of what can be
thought of as a particular list of genes. Each chromosome only has one form
of each gene in this list. Two chromosomes of the same type (same number)
will have the same list (e.g. eye colour, hair colour etc.) but will have
different variations/forms(alleles) of this list ... so one might have blue
eyes, brown hair, and the other might have green eyes, blonde hair. Usually,
someone's eyes are the same colour as each other so only one of these eye
colour genes comes through (dominates).

> If they don't pair up, why does colour blindness affect males
> predominantly?

Whenever you see something that predominately affects men you can guess that
it is because it is on the X chromosome. This is because men only have one
of these and women have two. If a woman has an X chromosome with the gene
for colour-blindness on it she will also have another X chromosome with
another gene which may be for 'not colour blind' (or normal) which is
dominant over the other gene. Because men only have one X chromosome, if
they have a gene for colour-blindness it will always come through.

> What exactly are chromatids, and why do we need them?

When a cell is duplicating all of its genetic material in meiosis (like you
talk about later) it does this by making copies of each chromosome ...
before the cell divides the copies stay attached to each other at one point
... each of the copies is called a chromatid. If you ever see a picture
(photograph) of a chromosome, it is usually at this stage of cell division
and looks like a large 'X', however, it is probably better to consider it
like a 'H' with each vertical bar of the 'H' as a chromatid, and the
horizontal bar as the attachment between the two.

> What are double-stranded chromosomes, and why do we need them?

Chromosomes are made of DNA. All of our DNA is double stranded.

> Why, before a cell is about to undergo meiosis, does it have twice the
> genetic information in a normal cell, when, if it had half, it could
> just divide straight away?

It actually doubles everything first then gives half of the original amount
to each of four new cells.

The reason it needs to have half the genetic information is because after
meiosis cells will become either sperm (male) or egg (female) ... when the
sperm and the egg join they then have the correct amount of chromosomes
again (two of each). If you didn't halve the genetic information in these
circumstances the child would have twice the correct amount and the
grandchild would have four times the correct amount of chromosomes and this
can cause many and complex problems.

The way the genetic information in halved is not entirely random. After
meiosis the new cells will each have one (instead of two) of each chromosome
type.

In mitosis (ordinary cell division that takes place as we grow ... and as
our hair and nails grow etc.) is different to this and it involves the cell
making copies of all of the chromosomes and then splitting in half with one
full set of chromosomes in each new cell.

> What is the point of crossover? Does it give an evolutionary advantage,
> or is it just a side effect?

An important part of evolution is allowing changes to happen ... crossing
over is another way of making changes ... so in the above example, a
crossover may have the effect of 'shuffling' the chromosomes so that blue
eyes and blonde hair are together on one chromosome and green eyes and brown
hair are together on the other.

> I would be very grateful if anyone could give up a few minutes of their
> time to answer some of these questions for me.

I hope this helps. I'm sorry if it gets too complicated but they were
complicated questions. I tried my best to explain things in a simple way but
still give you the information you were looking for.  Meiosis and mitosis
are the most difficult to explain ... you probably will need to find a book
or a web page with diagrams to illustrate what is going on. I was so
impressed by the fact that someone your age is interested in these things
(maybe there is such a thing as an educational computer game!) that I
thought I should answer and let you decide for yourself if it is too
difficult.

Good luck,

Aoife


From owner-chromosomes@net.bio.net Mon Apr 05 23:00:00 1999
Path: biosci!MAILHOST.TCS.TULANE.EDU!alustig
From: alustig@MAILHOST.TCS.TULANE.EDU ("Arthur J. Lustig")
Newsgroups: bionet.genome.chromosomes
Subject: (none)
Date: 6 Apr 1999 09:52:34 -0700
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POSTDOCTORAL FELLOWS TO STUDY TELOMERE STRUCTURE AND FUNCTION

        A postdoctoral position is available to investigate telomere
dynamics in Saccharomyces cerevisiae in the laboratory of Dr. Arthr J.
Lustig at Tulane University Medical Center. We have had a long-standing
fascination in telomere structure and function and are currently focusing
on two broad areas:

        1) THE MECHANISM OF TELOMERIC SILENCING
        RECENT REFERENCES
        Park et al., Sir3p Domains Involved in the Initiation of Telomeric
Silencing in Saccharomyces cerevisiae. Genetics 150:  977-986 (1998);
        Lustig, A., Mechamisms of silencing in Saccharomyces cerevisiae.
Current Opinions in Gentetics and Development 8: 233-239 (1998)

	        and

        2) NOVEL MODES OF TELOMERE SIZE CONTROL
        RECENT REFERENCES
         Li et al. A novel mechanism for telomere size control in
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        Lustig, A. The identification of telomerase subunits:  catalysing
telomere research. 7:299-302 (1997);
        Polotnianka et al.  The yeast Ku heterodimer is essential for
protection of the telomere against nucleolytic and recombinational
activities. Current Biology 831-834 (1998)

        Candidates should have a background in molecular biology and/or
genetics.  Background in yeast is preferable but not required. Applicants
must be highly motivated "self-starters".

        Interested candidates should send their c.v. either by e-mail, fax,
or mail to the address listed below.

Arthur J. Lustig
Associate Professor
Department of Biochemistry SL43
Tulane University Medical Center
1430 Tulane Avenue
New Orleans, LA 70112
phone: 504-584-3688
fax: 504-584-2739




From owner-chromosomes@net.bio.net Mon Apr 05 23:00:00 1999
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From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: Info on chromosomes in general, esp. meiosis
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<< Hello,
I'm Stephanie (13)

I am trying to plan, over my Easter holidays, a system for introducing
diploid cell (Is that the right term? I mean the possibility of
recessive genes, so double the DNA.)  into an artificial life game I
play. I keep coming up against a major stumbling block: chromosomes.

I especially want to clear up these points (I will try to get all the
terms right):
Do chromosomes carry dominant/recessive forms of the same gene (alleles)
together on one chromosome, or are they carried on different chromosomes
and the chromosomes 'pair up'?

If they don't pair up, why does colour blindness affect males
predominantly?

What exactly are chromatids, and why do we need them?

What are double-stranded chromosomes, and why do we need them?

Why, before a cell is about to undergo meiosis, does it have twice the
genetic information in a normal cell, when, if it had half, it could
just divide straight away?

What is the point of crossover? Does it give an evolutionary advantage,
or is it just a side effect?

I would be very grateful if anyone could give up a few minutes of their
time to answer some of these questions for me.
 >>


Stephanie;
you need a very basic text on cell division and learn the difference between
asexual division(mitosis) and sexual division(meiosis).
People may have trouble answering your questions for you appear to be asking
several questions as part of the same question.

Rcjohnsen@aol.com

From owner-chromosomes@net.bio.net Tue Apr 06 23:00:00 1999
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From: "giroire.ch" <giroire.ch@infonie.fr>
Newsgroups: bionet.genome.chromosomes
Subject: Re: chromosome 14
Date: Mon, 5 Apr 1999 22:26:51 +0100
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>
>deficiencies (diseases) associated with chromosome 14 can be found
>on the OMIM site:
>
>Hope this helps,
>
>francis
>
>--


je vous remercies pour ces renseignements, je n'y comprends pas grand chose
dans le domaine medicale surtout quand c'est specialisé et en plus ecrit en
anglais. Ce que j'ai cru comprendre c'est que le chromosome 14 avait quelque
chose a voir avec la maladie Alzheimer.

                                                    a bientot



christophe




From owner-chromosomes@net.bio.net Wed Apr 07 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!sunqbc.risq.qc.ca!newsflash.concordia.ca!pitt.edu!portc02.blue.aol.com!audrey01.news.aol.com!not-for-mail
From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: NEED INFO ON CHROMOSOMES 4,6,13,15 and 18<Bipolar Disorder>
Lines: 27
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<< Subject: NEED INFO ON CHROMOSOMES 4,6,13,15 and 18<Bipolar Disorder>
From: demian999@aol.com (Demian999)
Date: Tue, Mar 30, 1999 10:01 PM
Message-id: <19990330170110.13184.00000125@ng-ce1.aol.com>

I am currently doing a paper on Bipolar Disorder and I have discovered that the
gene for that disease is thought to be found on Chromosomes 4, 6, 13, 15 and
18.  The only problem i am facing is the fact that I can't find a site or
anyone that can tell me what those Chromosomes are for.  My paper is due
tomorrow<3/31> and i am panicing...PLEASE HELP!!!

Sincerely,
Jayson
 >>


I know I'm too late to help.  But in the future for medical things and genetic
keep in mind  the Entrez site http://www3.ncbi.nlm.nih.gov/Entrez/

the OMIM site http://www.ncbi.nlm.nih.gov/Omim/

or the   Medline site accessable through the virtual library
http://vlib.org

These are but a few

Roger

From owner-chromosomes@net.bio.net Sat Apr 10 23:00:00 1999
Path: biosci!SLIP.NET!grizzly
From: grizzly@SLIP.NET (Michael Sherrell)
Newsgroups: bionet.genome.chromosomes
Subject: LC/MS et al
Date: 11 Apr 1999 08:09:23 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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Newly available LC/mass spectrometers:
     Finnigan Navigator,18 months old; factory refurbished and installed with 90-day warranty included, $75,000.
     Micromass Platform II LC/MS, 1994, electrospray & APCI, Micromass-certified, LC included, $70,000
     VG Quattro GC/LC-MS/MS, 1993, 4000 amu, EI/CI, LSIMS, ESI and APCI, working in lab now, price negotiable
     IonSpec MALDI FT-MS hi-res hi-sensitivity 1995 model; "most sensitive on market" (for specs see http://www.ionspec.com/hiresmaldi.html); < $100,000
I also have these peptide and oligo synthesizers and sequencers for sale:
    ABI 394                 $12,500 (Valve blocks rebuilt; warranteed)
    ABI 390Z               $4,000 (50-100uM yields)
    ABI 431                 $12,500 (Rebuilt, warranteed)
    ABI 433                 $19,000 (ABI upgrade)
    PerSeptive 9050+,  $6,000 (As is/was working when decommissioned; add $3,500 for rebuild/warranty)
    ABI 373 stretch      $9,000 (Big dye upgrade; still under warranty)
    ABI 373 stretch      $7,000 (4-filter)
    ABI 377                 $97,500 (XL; 96 lanes; transferrable ABI service contract)
    ABI Procise 492     $59,000 obo (ABI-certified)
    ABI Procise 494     $84,000 (ABI-certified)
NMRs:
    Bruker AM360        $85,000 (Broadband; widebore; install included)
    Varian Gemini 300  $69,000 (Proton/carbon probe; freight, install, 90-day warr. included)
    Bruker AMX-500     $175,000 (4 probes; inverse electronics; 90-day warranty)
Also available:
     HP 5989B LC/MS engine, extended mass range (2000 amu), hex ion guide (HPLC, installation & warranty available): $45,000
     Hitachi 570 scanning electron microscope, Kevex detector, running now, $35,000.
     BD FACSVantage and assorted FACScans
Various other seqencers, synthesizers etc. are available; please inquire or check the website.

Michael Sherrell
Grizzly Analytical
707 887 2919/fax 707 887 9834
www.grizzlyanalytical.com

From owner-chromosomes@net.bio.net Sun Apr 11 23:00:00 1999
Path: biosci!daresbury!not-for-mail
From: zali25@cnv.es
Newsgroups: bionet.genome.chromosomes
Subject: ADV: Premium TV Channels......No Monthly Bills!
Date: 12 Apr 1999 07:01:01 +0100
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To be removed from our mailing list please call toll free 
800-242-0363 ext.2748

This is really cool!                    

              
            PREMIUM CHANNELS........Descrambled!              

                                         

EASY to assemble plans for only $6.00 !


YOU WILL BE WATCHING all your FAVORITE PAY STATIONS
featuring  MOVIES, SPORTS. Adult entertainment,
and any other scrambled signal NEXT WEEK!

You can EASILY assemble a cable descrambler in less than 30 minutes!
You have probably seen many advertisments for similar plans.........
BUT OURS are BETTER! 

We have compared it to all the others and have actually
IMPROVED the quality and SIMPLIFIED the design !!!


**  We even include PHOTOS! **


OUR PLANS ARE BETTER! 
We have NEW, EASY TO READ,EASY to assemble plans for only $6.00! 
We have seen them advertised for as much as $29.00 and you have 
to wait weeks to receive them!       


WHAT THE OTHERS SAY IS TRUE!

Parts are available at  "The TV HUT"  or any electronics store.  
Trademark rights do not allow us to use a national electronics 
retail chains' name but there is one in your town!  


Call and ask them BEFORE you order! 
They are very familiar with these plans! 
 


You will need these easy to obtain parts :

 270-235                        mini box
 271-1325                       2.2k ohm resistor 
 278-212                        chasis connectors
 RG59 coaxial cable             #12 copper wire 
 Variable capacitor


     They may have to  special order the variable capacitor,
     But WHY WAIT for a special order?  WE have them!


     WE have secured a supply of the capacitors directly from
     the manufacturer and We WILL include one with your plans
     for an ADDITIONAL  $10.00 only!
    

     All you need now is the EASY TO ASSEMBLE plans to
     show you how to assemble this educational device in 
     only 30 MINUTES! 

 It is LEGAL, providing of course you use these plans for 
 EDUCATIONAL PURPOSES only. See first hand and LEARN how this
 SIMPLE circuitry works! If you intend to use these plans for
 any other purpose DO NOT ORDER them.  
   

 IT'S FUN TO BUILD!  


We're sure you'll enjoy this project!                            
This is a unique opportunity for hobbiest of ANY skill level
to learn simple circuitry!


                Learn how easy descrambling is!           

                $ 6.00     for plans only                        
                
                $10.00     for variable capacitor only            

                $16.00     for The easy to assemble plans and one 
                           variable capacitor!	

                 


Please send check or money order payable to:           

Kraftworks
P.O. Box 11752
San Rafael, Ca.
94912         		            

WE pay postage and handling!          
Please allow 14 days for delivery.


* For express service please include a self address 
  stamped envelope with .66 postage added

Thank
You


11
11
e

From owner-chromosomes@net.bio.net Sun Apr 11 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!europa.clark.net!210.120.128.201!newsfeed.dacom.co.kr!news.bora.net.POSTED!not-for-mail
Newsgroups: sci.bio.technology,bionet.cellbiol,bionet.genome.chromosomes,sci.bio.misc,sci.bio.technology
From: dkim@bio.bmelab.co.kr (Desok Kim)
Subject: database on centromere location
Organization: BIOMEDLAB INC.
Keywords: chromosome, feature extraction, centromere, on-line data base
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Xref: biosci bionet.cellbiol:11628 bionet.genome.chromosomes:2391

Hello, does anyone help me to find some on line database  that
contains information on centromere location of normal  human chromosomes?
According to Jim Piper's 1989 paper on "On fully automatic feature measurement 
for banded chromosome classfification," Cytometry 10:242-255, there must be
at least three data bases on centromere location: MRC, Edinburgh, Scotland
Righospitalet, Copenhagen, Jefferson Medical College, Philadelphia.  Are any 
of them on line?  Please let me know through e-mail.  Thanks in advance. Desok

Desok Kim, PhD
Biomedlab, Inc. Dongsoong Bldg 401
Dongsoong-Dong 1-49, Seoul, Korea 110-510
Tel: 82-2-747-9308
Fax: 82-2-747-4395

From owner-chromosomes@net.bio.net Mon Apr 12 23:00:00 1999
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From: gwilliam@hgmp.mrc.ac.uk (Gary Williams)
Newsgroups: bionet.genome.chromosomes
Subject: Re: database on centromere location
Date: 13 Apr 1999 08:17:08 GMT
Organization: UK HGMP Resource Centre
Lines: 17
Message-ID: <7euui4$ilh$1@niobium.hgmp.mrc.ac.uk>
References: <QehQ2.1263$UC6.2266@news.bora.net> <19990412204700.17768.00001987@ng13.aol.com>
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In article <19990412204700.17768.00001987@ng13.aol.com>,
Rcjohnsen <rcjohnsen@aol.com> wrote:

>The MRC site is apparently 
>http://www.hgmp.mrc.ac.uk/
>but didn't have much luck viewing human chromosomes

You were probably trying to find GenomeWeb:
http://www.hgmp.mrc.ac.uk/GenomeWeb/

This contains a list of human chromosome-specific databases:
http://www.hgmp.mrc.ac.uk/GenomeWeb/human-gen-db-chromosomes.html


Gary Williams               Tel: +44 1223 494522  Fax: +44 1223 494512
mailto:G.Williams@hgmp.mrc.ac.uk            http://www.hgmp.mrc.ac.uk/
Bioinformatics,MRC HGMP Resource Centre,Hinxton,Cambridge, CB10 1SB,UK

From owner-chromosomes@net.bio.net Mon Apr 12 23:00:00 1999
Path: biosci!BWC.DE!dibemoi99
From: dibemoi99@BWC.DE
Newsgroups: bionet.genome.chromosomes
Subject: ADV: Premium TV Channels......No Monthly Bills!
Date: 12 Apr 1999 22:07:17 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 108
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To be removed from our mailing list please call toll free 
800-242-0363 ext.2748

This is really cool!                    

              
            PREMIUM CHANNELS........Descrambled!              

                                         

EASY to assemble plans for only $6.00 !


YOU WILL BE WATCHING all your FAVORITE PAY STATIONS
featuring  MOVIES, SPORTS. Adult entertainment,
and any other scrambled signal NEXT WEEK!

You can EASILY assemble a cable descrambler in less than 30 minutes!
You have probably seen many advertisments for similar plans.........
BUT OURS are BETTER! 

We have compared it to all the others and have actually
IMPROVED the quality and SIMPLIFIED the design !!!


**  We even include PHOTOS! **


OUR PLANS ARE BETTER! 
We have NEW, EASY TO READ,EASY to assemble plans for only $6.00! 
We have seen them advertised for as much as $29.00 and you have 
to wait weeks to receive them!       


WHAT THE OTHERS SAY IS TRUE!

Parts are available at  "The TV HUT"  or any electronics store.  
Trademark rights do not allow us to use a national electronics 
retail chains' name but there is one in your town!  


Call and ask them BEFORE you order! 
They are very familiar with these plans! 
 


You will need these easy to obtain parts :

 270-235                        mini box
 271-1325                       2.2k ohm resistor 
 278-212                        chasis connectors
 RG59 coaxial cable             #12 copper wire 
 Variable capacitor


     They may have to  special order the variable capacitor,
     But WHY WAIT for a special order?  WE have them!


     WE have secured a supply of the capacitors directly from
     the manufacturer and We WILL include one with your plans
     for an ADDITIONAL  $10.00 only!
    

     All you need now is the EASY TO ASSEMBLE plans to
     show you how to assemble this educational device in 
     only 30 MINUTES! 

 It is LEGAL, providing of course you use these plans for 
 EDUCATIONAL PURPOSES only. See first hand and LEARN how this
 SIMPLE circuitry works! If you intend to use these plans for
 any other purpose DO NOT ORDER them.  
   

 IT'S FUN TO BUILD!  


We're sure you'll enjoy this project!                            
This is a unique opportunity for hobbiest of ANY skill level
to learn simple circuitry!


                Learn how easy descrambling is!           

                $ 6.00     for plans only                        
                
                $10.00     for variable capacitor only            

                $16.00     for The easy to assemble plans and one 
                           variable capacitor!	

                 


Please send check or money order payable to:           

Kraftworks
P.O. Box 11752
San Rafael, Ca.
94912         		            

WE pay postage and handling!          
Please allow 14 days for delivery.


* For express service please include a self address 
  stamped envelope with .66 postage added


From owner-chromosomes@net.bio.net Mon Apr 12 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!feeder.qis.net!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail
From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: database on centromere location
Lines: 28
NNTP-Posting-Host: ladder05.news.aol.com
X-Admin: news@aol.com
Date: 13 Apr 1999 00:47:00 GMT
Organization: AOL http://www.aol.com
References: <QehQ2.1263$UC6.2266@news.bora.net>
Message-ID: <19990412204700.17768.00001987@ng13.aol.com>

<< Subject: database on centromere location
From: dkim@bio.bmelab.co.kr (Desok Kim)
Date: Mon, Apr 12, 1999 7:26 AM
Message-id: <QehQ2.1263$UC6.2266@news.bora.net>

Hello, does anyone help me to find some on line database  that
contains information on centromere location of normal  human chromosomes? >>


Try the site
http://www.genlink.wustl.edu/

The MRC site is apparently 
http://www.hgmp.mrc.ac.uk/
but didn't have much luck viewing human chromosomes

also try Normal Human Chromosome at
http://raven.umnh.utah.edu/units/karyotyping/normal.html

or
Introduction to chromosomes at
http://raven.umnh.utah.edu/review/disease/chromosomes.html

or cytogenetics Gallery at
http://www.pathology.washington.edu/Cyto_gallery/

I hope this is helpful
Roger J

From owner-chromosomes@net.bio.net Tue Apr 13 23:00:00 1999
Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!208.134.241.18!newsfeed.cwix.com!152.163.199.19!portc03.blue.aol.com!audrey01.news.aol.com!not-for-mail
From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: database on centromere location
Lines: 17
NNTP-Posting-Host: ladder05.news.aol.com
X-Admin: news@aol.com
Date: 14 Apr 1999 18:11:47 GMT
Organization: AOL http://www.aol.com
References: <7euui4$ilh$1@niobium.hgmp.mrc.ac.uk>
Message-ID: <19990414141147.01907.00000595@ng27.aol.com>

<< You were probably trying to find GenomeWeb:
http://www.hgmp.mrc.ac.uk/GenomeWeb/

This contains a list of human chromosome-specific databases:
http://www.hgmp.mrc.ac.uk/GenomeWeb/human-gen-db-chromosomes.html


Gary Williams               Tel: +44 1223 494522  Fax: +44 1223 494512
mailto:G.Williams@hgmp.mrc.ac.uk            http://www.hgmp.mrc.ac.uk/
Bioinformatics,MRC HGMP Resource Centre,Hinxton,Cambridge, CB10 1SB,UK
 >>



Thanks Gary,

Roger J.

From owner-chromosomes@net.bio.net Thu Apr 15 23:00:00 1999
Path: biosci!ESOTRONIC.DE!kabero75
From: kabero75@ESOTRONIC.DE (wnefexe1)
Newsgroups: bionet.genome.chromosomes
Subject: wine and beer ....
Date: 16 Apr 1999 05:39:56 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 69
Sender: daemon@net.bio.net
Distribution: world
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 TO REMOVE, OR TO SEND MASS EMAIL TO 1 MILLION, SEE END OF MESSAGE.
 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

              wine & beer is a blessing in moderation.

John & Phyllis Rice, Ministers
1268 Cherrybark Rd., Apopka, (Orlando suburb) FL 32703 
To talk to John Email: johnmrice@johnmrice.com Phone/Fax (407) 886-7063
To talk to Phyllis Email: praisesing@earthlink.net Phone (407) 886-1419
Web Page: http://www.johnmrice.com

For prayer/fellowship/counselling or comments/questions/encouragement 
in the spirit of Holy Ghost, please reach us at one of the addresses or 
phone. When calling on phone, leave your phone number & an e-mail/mail 
address. All requests that want a return phone call will be returned 
within the U.S., outside U.S. corresspondance will be by e-mail.

God has put a tremendous desire for us to minister to you by the 
anointing of the Holy Ghost, so I truely count it an honor for you to 
send your needs to us. And we look forward to being a blessing!!! We 
have a special desire for those who desire biblical counseling so 
please feel free to share & we shall give you wisdom from God's word 
with the help of Holy Ghost. We believe wine (or beer) is a blessing 
in moderation, w/o excess. (Many scriptures which confirm this fact.) 
(Gen. 14:18),Heb.7:3,6;Micah5:2;Luke22:14-30;Psalm110, Heb5:10,6:20,
7:3,17,21,23-28;Heb.7:4-8,John8:55-59;Heb.7:2,1Cor.1:30,Heb1:8, 
(Gen 27:28): (John 2:1-11) Many more scriptures on wine which refer 
it as a blessing. (Beer is a weaker alcoholic substance than wine & 
made of rice & wheat which are also found in the Bible.) 

Those who don't know God, but are seeking we believe it is OK for them 
to have some wine/beer in moderation while Studying The New Testament. 
1st, before trying to read God's word in the Old Testament. The OT is 
for mature believers. Cannot be understood (mystery) until living the 
New Testament/Covenant born-again experience. (Look up mystery Mark 
4:11 & others). 

Believe in the Jewishness of God & his special devotion to Israel, 
Jerusalem, & the Jews. that to be better representatives for God, we 
must learn our Jewish roots & be genuine friends to the Jews around the 
world & Israel in prayer & action. This means we must identify 
ourselves as Jews ourselves, adopted into the Jewish family, & be 
willing to be persecuted for this truth, whatever the price, with the 
same perseverence & sacrifice for this fact as our faith in Yeshua as 
Lord & Savior/Messiah, even unto Death.

Look for opportunities to become friends with our Jewish family. Learn 
our culture from them. Learn the Hebrew language, become involved with 
the Jewish community, however, we need to accept them as they are & not 
force Jesus upon them. We need to be genuine friends & learn from them & 
let God take care of bringing them to their Messiah by our love for 
them. God shall bless & fulfill needs that both of us, natural & 
adopted, have in our souls & spirits. Attend a local synagogue. Join a 
Jewish community center. Seek their friendship & then be a genuine 
friend.

Baruch HaShem Adoinai Yeshua HaMashiach/Blessed is the name of our Lord 
Jesus the Messiah,

John & Phyllis Rice
--------------------------------------------------------------------
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d415d65

From owner-chromosomes@net.bio.net Mon Apr 19 23:00:00 1999
Path: biosci!CSHL.ORG!boyce
From: boyce@CSHL.ORG (Joan Boyce)
Newsgroups: bionet.genome.chromosomes
Subject: 1999 Source Book Available Free to Researchers
Date: 20 Apr 1999 11:42:35 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 17
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <371CC948.41AA@cshl.org>
Reply-To: boyce@cshl.org
NNTP-Posting-Host: net.bio.net

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From owner-chromosomes@net.bio.net Tue Apr 20 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!newsfeed.berkeley.edu!dispose.news.demon.net!demon!newsfeed.gamma.ru!Gamma.RU!nntpgate.globalserve.net!news.globalserve.net!not-for-mail
From: "Donald Cameron" <camerdw@globalserve.net>
Newsgroups: bionet.genome.chromosomes
Subject: chromosome 12 disorder
Date: Wed, 21 Apr 1999 12:46:42 -0500
Organization: Globalserve Communications Inc.
Message-ID: <7fkvri$lf6$1@whisper.globalserve.net>
NNTP-Posting-Host: dialin100.hamilton.globalserve.net
X-Trace: whisper.globalserve.net 924713650 21990 209.90.138.163 (21 Apr 1999 16:54:10 GMT)
X-Complaints-To: abuse@globalserve.net
NNTP-Posting-Date: 21 Apr 1999 16:54:10 GMT
X-Newsreader: Microsoft Outlook Express 4.72.3110.5
X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3
Lines: 6

any information about this disorder would be greatly appreiciated.
any web sites books experts support groups etc.

thanks in advance for your help.



From owner-chromosomes@net.bio.net Tue Apr 20 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!newsfeed.amsterdam.nl.net!sun4nl!gate.news.unisource.nl!xs4all!not-for-mail
From: "Dutchy" <kevin1@xs4all.nl>
Newsgroups: bionet.genome.chromosomes
Subject: Re: chromosome 12 disorder
Date: Wed, 21 Apr 1999 21:43:58 +0200
Organization: XS4ALL Internet BV
Lines: 15
Message-ID: <7fl9nk$jeb$1@news1.xs4all.nl>
References: <7fkvri$lf6$1@whisper.globalserve.net>
Reply-To: "Dutchy" <kevin1@xxxiname.com>
NNTP-Posting-Host: dc2-modem475.dial.xs4all.nl
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Donald Cameron wrote <7fkvri$lf6$1@whisper.globalserve.net>...
>any information about this disorder would be greatly appreiciated.
>any web sites books experts support groups etc.
>
>thanks in advance for your help.
>
>
    Donald I know of a disorder of a mutation of chromosome 12 dat is cauld
ORW, Osler-Weber-Rendu syndrome take a look
at my homepage http://www.xs4all.nl/~kevin1
With regards
Kevin



From owner-chromosomes@net.bio.net Sat Apr 24 23:00:00 1999
Path: biosci!info.co.il!info
From: info@info.co.il
Newsgroups: bionet.genome.chromosomes
Subject: You won a prize!
Date: 25 Apr 1999 07:27:54 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 4
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199904251427.HAA13120@net.bio.net>
NNTP-Posting-Host: net.bio.net

Hi biochrom
You've won a Free Web Site!

Go Get It at http://www.treeway.com 

From owner-chromosomes@net.bio.net Sun Apr 25 23:00:00 1999
Path: biosci!bloom-beacon.mit.edu!news.kodak.com!news-nysernet-16.sprintlink.net!news-east1.sprintlink.net!news-peer-europe.sprintlink.net!news.sprintlink.net!howland.erols.net!hub1.ispnews.com!news14.ispnews.com.POSTED!not-for-mail
From: moqegk@virtualbanner.com
Newsgroups: bionet.genome.chromosomes
Subject: Banner Exchange  4309
Lines: 3
Message-ID: <G71V2.13630$qj7.230699@news14.ispnews.com>
NNTP-Posting-Host: 207.252.233.37
X-Trace: news14.ispnews.com 925146726 207.252.233.37 (Mon, 26 Apr 1999 13:12:06 EDT)
NNTP-Posting-Date: Mon, 26 Apr 1999 13:12:06 EDT
Date: Mon, 26 Apr 1999 17:12:06 GMT

Has anyone seen that new banner exchange out there. Its called VirtualBanner. They are giving away 25000 free impressions just for signing up. They also have a FULL TIME 2:1 exchange ratio and do banner promotion. Check them out at http://www.virtualbanner.com
lknqxlbnfcxrpltw


From owner-chromosomes@net.bio.net Sun Apr 25 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!logbridge.uoregon.edu!dispose.news.demon.net!demon!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail
From: fundurloan@aol.com (FUNDURLOAN)
Newsgroups: bionet.genome.chromosomes
Subject: chromosome 1 reversed
NNTP-Posting-Host: ladder05.news.aol.com
X-Admin: news@aol.com
Date: 26 Apr 1999 22:13:06 GMT
Organization: AOL http://www.aol.com
Message-ID: <19990426181306.08645.00001836@ng122.aol.com>
Lines: 11

I am expectant father whose wife is due in August with our 3rd child(a boy as
were the first two both heatlhy active children). My wife had an
amniosyntesis(I am not in the medical or science field so please forgive my
spelling). from the results part of chromosome 1 was reversed.My wife and I
were both tested and the results were normal so i am naturally concerned. All
of the genetic material is there but the geneticist has never seen this before
and is looking into this further. i am trying to find any information i can on
this subject if you know of anywhere i can find more info please let me know. I
am not concerned about anonymity so please forward this to someone who may know
more on the subject. I can be e-mailed at fundurloan@aol.com. thank you.
Scott Bryant

From owner-chromosomes@net.bio.net Mon Apr 26 23:00:00 1999
Path: biosci!newshost.lanl.gov!awabi.library.ucla.edu!128.230.129.106!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail
From: lepler4184@aol.com (LEpler4184)
Newsgroups: bionet.genome.chromosomes
Subject: Huntington's disease
Lines: 5
NNTP-Posting-Host: ladder05.news.aol.com
X-Admin: news@aol.com
Date: 27 Apr 1999 02:09:41 GMT
Organization: AOL http://www.aol.com
Message-ID: <19990426220941.14432.00000263@ng-co1.aol.com>

What is the gene called for Huntington's disease on Chromosome 4?



              Thanks

From owner-chromosomes@net.bio.net Mon Apr 26 23:00:00 1999
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.genome.chromosomes
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 27 Apr 1999 02:00:12 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 233
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199904270900.CAA18484@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.


From owner-chromosomes@net.bio.net Tue Apr 27 23:00:00 1999
Path: biosci!rutgers!rockyd.rockefeller.edu!news-nysernet-5.sprintlink.net!news-east1.sprintlink.net!news-peer1.sprintlink.net!news.sprintlink.net!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey03.news.aol.com!not-for-mail
From: wiserwiz@aol.com (WiserWiz)
Newsgroups: bionet.genome.chromosomes
Subject: Membrane Microarrays
Lines: 22
NNTP-Posting-Host: ladder06.news.aol.com
X-Admin: news@aol.com
Date: 28 Apr 1999 19:59:56 GMT
Organization: AOL http://www.aol.com
Message-ID: <19990428155956.27343.00000004@ng-cs1.aol.com>

I need your help! The Pall Specialty Materials group has begun the Membrane
Microarray Initiative (MMI), a program to optimize membranes for microarrays.
In
addition to our existing membranes, we are developing new materials which will
provide superior benefits for DNA/protein detection in an array format. If you
would like to become part of the MMI program please contact me at 800-362-6276
(
Jason_Alter@Pall.com). As a member you will receive our free, bimonthly,
electronic newsletter with tips, frequently asked questions, protocols, etc.
for
membrane-based diagnostics, arrays and high throughput screening. Also, all
members will receive a free gift for joining, and  a drawing will be held from
everyone who joins the MMI program by August 1, 1999. The winner will receive a
$100 gift check

I hope that you are as interested in membrane-based microarrays as I am. Thank
you for your interest.

Sincerely,

Jason M. Alter, Ph.D.


From owner-chromosomes@net.bio.net Thu Apr 29 23:00:00 1999
From: "Uma Chrissie" <vum@np.edu.sg>
Sender: "Uma Chrissie" <vum@npnsnews>
Reply-To: "Uma Chrissie" <vum@np.edu.sg>
Subject: Karyotyping
Newsgroups: bionet.genome.chromosomes
X-User-Info: 153.20.24.68    vum npnsnews 
NNTP-Posting-Host: 153.20.15.92
Message-ID: <37293750.0@nsuxnews>
Date: 30 Apr 1999 12:53:36 +0800
X-Trace: 30 Apr 1999 12:53:36 +0800, 153.20.15.92
Lines: 17
Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.amsterdam.nl.net!sun4nl!uunet!ams.uu.net!ffx.uu.net!in5.uu.net!newsfeed.attap.net!mango.singnet.com.sg!dahlia.singnet.com.sg!ocean.singnet.com.sg!nsuxnews!153.20.15.92



 Dear Reader,

 I am interested in determining the chromosome number of the red-claw crayfish.
I have done a few trials using the live fries which have been incubated in colchicine, after which they are ground against a wire mesh then treated with a hypotonic solution,fixed and stained.
The results have been very disappointing.
Can someone please tell me what to look for in a metaphase?
Will I always see "X"s and "V"s?
Is there a better way of getting a cell suspension using the fries without lysing the cells?
What are the best ways in achieving well spread chromosomes for crustacean species?

Please help!

Chrissie
vum@np.edu.sg


From owner-chromosomes@net.bio.net Thu Apr 29 23:00:00 1999
Path: biosci!news.stanford.edu!newsfeed.stanford.edu!news-feed.inet.tele.dk!bofh.vszbr.cz!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!spamz.news.aol.com!audrey03.news.aol.com!not-for-mail
From: rcjohnsen@aol.com (Rcjohnsen)
Newsgroups: bionet.genome.chromosomes
Subject: Re: Huntington's disease
Lines: 18
NNTP-Posting-Host: ladder06.news.aol.com
X-Admin: news@aol.com
Date: 30 Apr 1999 07:46:18 GMT
Organization: AOL http://www.aol.com
References: <19990426220941.14432.00000263@ng-co1.aol.com>
Message-ID: <19990430034618.10951.00000397@ng-cm1.aol.com>

<< Subject: Huntington's disease
From: lepler4184@aol.com (LEpler4184)
Date: Tue, Apr 27, 1999 2:09 AM
Message-id: <19990426220941.14432.00000263@ng-co1.aol.com>

What is the gene called for Huntington's disease on Chromosome 4?

 >>


Try the OMIM site at
http://www.ncbi.nlm.nih.gov/Omim/  

search the database using the keyword
Huntington's Disease.

Roger J.


From owner-chromosomes@net.bio.net Thu Apr 29 23:00:00 1999
Path: biosci!MAIL.JINRO.CO.KR!koi8
From: koi8@MAIL.JINRO.CO.KR (tyreorn)
Newsgroups: bionet.genome.chromosomes
Subject: $$$ One Year Guarantee!! $$$ L@@K NOW $$$
Date: 30 Apr 1999 06:55:05 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 35
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <19990430657IAA788@guncerso.verthu.etri.re.kr>
NNTP-Posting-Host: net.bio.net


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