From owner-diagnostics@net.bio.net Sat Jun 03 23:00:00 1995
Path: biosci!MERCURY.UARK.EDU!DRHOADS
From: DRHOADS@MERCURY.UARK.EDU ("Douglas Rhoads")
Newsgroups: bionet.diagnostics
Subject: Re: Roche vs Promega Latest
Date: 4 Jun 1995 08:11:30 -0700
Organization: University of Arkansas
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> To:            diagnost@net.bio.net
> From:          odonnell@sasa.gov.uk (Kevin O'Donnell)
> Subject:       Roche vs Promega Latest
> Date:          Thu, 1 Jun 1995 13:15:57 GMT

> Scientists are getting caught in the cross-fire in the legal battle between 
> Roche and promega over the taq polymerase (used in PCR)patent. 
> Briefly, Promega are trying to get the patent overturned in the US 
> because it is 'prior art'  i.e. they maintain that taq had been described 
> previous to the patent being granted to Cetus (who sold it to Roche).
> 
> The latest thing is that Roche have compiled a list of over 200 US 
> scientists in universities and laboratories who they say have acted illegally. 
> The list seems to consist of people who have published papers in which 
> the source of their taq was Promega.   The full list is available on 
> Promega's WWW page (http://www.promega.com) as are more details 
> about the litigation.
> 
> The European taq patent has been withdrawn, pending further 
> investigation, partly as a result of the Promega action.
> 
> I should say here that this info is distilled from the Promega press release 
> which may not be the most objective source. 
> 
> I would also like to declare an interest: I am sick and tired of being ripped 
> off by taq prices several times the real cost.
>   
> Kevin O'Donnell
> Scottish Agricultural Science Agency    
> Edinburgh
> Scotland                                           
> 

Darn, I hate being no one.  I'm not on the list.  I couldn't agree 
more about being extorted.  Even Promega's price for Taq is extremely 
high when you consider how long it takes to purify that enzyme.  From 
the published reports it looks like you can make about $2,000,000 
(US) worth of Taq Pol (using Promega's discount price) or about 
$5,000,000 if you use PE prices, in about 2 days and the equipment is 
nothing.  The list of names looks like they only went through a few 
selected journals, nothing I publish in.  I just wonder how long the 
slide towards patent-and-sue, will continue in science.  If Hoffman 
can make stand a Universal monopoly on use of any thermal stable 
polymerase and every possible use of PCR then we will all be paying 
massive tariffs and that will drive most of us out of the business.  
Money is too tight right now in funding sources without having the 
Taqs (Tax) Man raising the rates.

//========================================================\\
||Doug Rhoads              || Dept. of Biological Sciences||
||drhoads@mercury.uark.edu || 601 Science Engineering     ||
||drhoads@uafsysb.uark.edu || University of Arkansas      ||
||501-575-3251             || Fayetteville, AR 72701      ||
==========================================================||
||     My Dogma Just Got Run Over by Someone's Karma      ||
\\========================================================//

From owner-diagnostics@net.bio.net Sat Jun 03 23:00:00 1995
Newsgroups: bionet.diagnostics
Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!pipex!sasa.gov.uk!news
From: odonnell@sasa.gov.uk (Kevin O'Donnell)
Subject: Roche vs Promega Latest
Organization: Scottish Agricultural Science Agency
Date: Thu, 1 Jun 1995 13:15:57 GMT
Message-ID: <D9HwuL.H5A@jura.sasa.gov.uk>
X-Newsreader: WinVN 0.91.6
Sender: news@jura.sasa.gov.uk (Usenet)
Lines: 26

Scientists are getting caught in the cross-fire in the legal battle between 
Roche and promega over the taq polymerase (used in PCR)patent. 
Briefly, Promega are trying to get the patent overturned in the US 
because it is 'prior art'  i.e. they maintain that taq had been described 
previous to the patent being granted to Cetus (who sold it to Roche).

The latest thing is that Roche have compiled a list of over 200 US 
scientists in universities and laboratories who they say have acted illegally. 
The list seems to consist of people who have published papers in which 
the source of their taq was Promega.   The full list is available on 
Promega's WWW page (http://www.promega.com) as are more details 
about the litigation.

The European taq patent has been withdrawn, pending further 
investigation, partly as a result of the Promega action.

I should say here that this info is distilled from the Promega press release 
which may not be the most objective source. 

I would also like to declare an interest: I am sick and tired of being ripped 
off by taq prices several times the real cost.
  
Kevin O'Donnell
Scottish Agricultural Science Agency    
Edinburgh
Scotland                                           

From owner-diagnostics@net.bio.net Mon Jun 05 23:00:00 1995
Path: biosci!III1.III.NET!irc
From: irc@III1.III.NET
Newsgroups: bionet.diagnostics
Subject: MS CONFERENCE - CALL FOR STUDENTS
Date: 6 Jun 1995 07:45:39 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 113
Sender: daemon@net.bio.net
Distribution: world
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Reply-To: irc@iii1.iii.net
NNTP-Posting-Host: net.bio.net

> In response to queries for discounted
> rates for students, a discounted
> registration fee is now available.
> 
>       STUDENT REGISTRATION: $125.
> 
> The registration includes all sessions,
> speaker documentation, breakfast on both
> days, lunch on monday, and a reception
> on monday evening.  Register Now!
> 
>  ***********************************
>                ADVANCES
>             
>                 IN THE
>   
>        DIAGNOSIS AND TREATMENT
>       
>                   OF
>    
>          MULTIPLE SCLEROSIS
>   *********************************
>   
>             **************
>           *JUNE 19-20, 1995*
>            The Charles Hotel
>        Cambridge, Massachusetts
>         **********************
>              sponsored by
>   
>              NATIONAL
>              MULTIPLE SCLEROSIS
>              SOCIETY
>          (Massachusetts Chapter)
>   
>   International Research Communications
>   
>   _________________________________________
>   The exponential growth in our knowledge
>   of multiple sclerosis has led to exciting 
>   new diagnostic and treatment
>   methodologies.  This program brings
>   together the most prominent scientists
>   from both clinical and basic research set-
>   tings to discuss current progress in the
>   diagnosis and treatment of multiple
>   sclerosis.  Topics covered at this conference
>   will provide a comprehensive survey of 
>   specific laboratory and clinical issues
>   within the context of four broad sessions;
>   novel diagnostic procedures, experimental
>   animal models, leukocyte trafficking and 
>   specific treatments.
>   
>   This conference will be of interest to re-
>   searchers and physicians involved in the 
>   study of multiple sclerosis, autoimmune 
>   diseases and other neuroimmunological
>   disorders.  The program is designed to
>   encourage interaction between clinicians
>   and basic researchers.  The laboratory re-
>   search and clinical findings presented at this
>   conference will help to form the basis for 
>   new diagnostic and treatment strategies 
>   into the next century.
>   _________________________________________
>   
>   *****************************************
>   KEYNOTE ADDRESS
>   Dr. Abul K. Abbas, Harvard Medical School
>   
>   DIAGNOSIS AND COURSE OF MS
>   Dr. John F. Kurtzke, VAMC, Washington DC (chair)
>   Dr. William A. Sibley, University of Arizona
>   Dr. Gary Birnbaum, University of Minnesota
>   Dr. Donald W. Paty, University of British Columbia
>   
>   EXPERIMENTAL MODELS OF MS
>   Dr. Stephen D. Miller, Cleveland Clinic Foundation (chair)
>   Dr. William J. Karpus, Northwestern University
>   Dr. Vijay Kuchroo, Harvard Medical School
>   Dr. Arthur A. Vandenbark, VAMC, Portland, Oregon
>   Dr. Caroline Whitacre, Ohio State University
>   
>   LEUKOCYTE TRAFFICKING IN MS AND EAE
>   Dr. Richard M. Ransohoff, Cleveland Clinic Foundation (chair)
>   Dr. Bruce D. Trapp, Cleveland Clinic Foundation
>   Dr. William F. Hickey, Dartmouth Medical School
>   Dr. Mariano Elices, Cytel Corporation
>   Dr. Donald E. Staunton, ICOS Corporation
>   
>   SPECIFIC TREATMENTS FOR MS
>   Dr. Anthony T. Reder, University of Chicago (chair)
>   Dr. Robert Knobler, Thomas Jefferson University
>   Dr. Jeffrey A. Cohen, Cleveland Clinic Foundation
>   Dr. John H. Noseworthy, Mayo Clinic
>   Dr. Howard L. Weiner, Harvard Medical School
>   
>   *********************************************
>   For more information about the conference
>   and how to register, please call International
>   Research Communications at (617) 489-0443
>   or (800) 495-1073 or send E-mail to 
>                  
>                  IRC@iii.net
>   
>   
>  
>  
> 
> 



From owner-diagnostics@net.bio.net Tue Jun 06 23:00:00 1995
Newsgroups: bionet.diagnostics
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!news.sprintlink.net!crash!kiehl
From: b3748@cts.com (Bryan Kiehl)
Subject: Borrelia Evaluatoin
Organization: CTSNET
Date: Wed, 7 Jun 1995 01:10:50 GMT
Message-ID: <3r2uaq$97s_003@kiehl.cts.com>
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We have finished a controlled field evaluation of a new Lyme disease serology 
product and would like to "beta" test it in several US sites. These kits will 
not be sold into the US until FDA cleared. Sites must have reasonable access 
to patient history and use serology test methods that include a western blot 
analysis using criteria similar to those described by Dressler.

If interested, please contact me at b3748@cts.com or by FAX at 619-592-9400.

Thanks,
Bryan Kiehl

Bryan Kiehl
GenBio
15222-A Avenue of Science
San Diego, CA 92128
(619) 592-9300, ext 309
(619) 592-9400 [FAX]

From owner-diagnostics@net.bio.net Tue Jun 06 23:00:00 1995
Path: biosci!OP1.UP.AC.ZA!KPAT1
From: KPAT1@OP1.UP.AC.ZA ("Fred Reyers")
Newsgroups: bionet.diagnostics
Subject: HELP - Protein Electrophoresis on Cellulose Acetate Foil
Date: 7 Jun 1995 01:18:34 -0700
Organization: University of Pretoria
Lines: 34
Sender: daemon@net.bio.net
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Message-ID: <71DCFB68EA@op1.up.ac.za>
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Diagnost boffins

We have used the Beckman Microzone Electrophoresis system with their 
CA foil for decades (and have been VERY satisfied). We are informed 
that Beckman no longer make the foil (57 x 145 mm) and have found 
another source (Merck markets the BDH product # 44319). This seemed 
to be the answer to our prayers (those who run electrophoresis will 
know that once you have a system that works - you hang on to it). 
However, we cannot get good clearing of the BDH membrane for 
densitometric scanning using the Methanol/Acetic Acid/Heat method 
that worked on the Beckman foils.
We have contacted Merck repeatedly but they appear to have no 
interest in finding the answer. We have tried a variation of 
Methanol/Acetic acid concentrations as well as different temperatures 
- all to no avail.

Is there anyone out there who has experience with this product who 
can advise us?

Thanks, in anticipation of a flood of solutions (excuse the pun).

Fred

Fred Reyers (Prof & Head: Section of Clinical Pathology)
Department of Medicine
Faculty of Veterinary Science
P.Bag X04, ONDERSTEPOORT, 0110,
Rep. of South Africa
Tel: 27-12-529 8288
FAX: 27-12-529 8308 or 27-12-344 2107 (Home)

                       "The great tradgedies of science
            are the slaying of beautiful hypotheses by ugly facts"
                              (Huxley)

From owner-diagnostics@net.bio.net Thu Jun 08 23:00:00 1995
Path: biosci!ZEUS.DATASRV.CO.IL!ila2027
From: ila2027@ZEUS.DATASRV.CO.IL (Falk Fish)
Newsgroups: bionet.diagnostics
Subject: Re: HELP - Protein Electrophoresis on Cellulose Acetate Foil
Date: 8 Jun 1995 16:38:02 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 8
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <Pine.3.89.1.2.9506090204.A16705-0100000@zeus.datasrv.co.il>
References: <71DCFB68EA@op1.up.ac.za>

I do not know about this technology, but if CA stands for Cellulose 
Acetate, try toluene or other solvents.

I hope it works for you, otherwise it is a nice theory.

Falk Fish, Tel-Aviv, Israel



From owner-diagnostics@net.bio.net Thu Jun 08 23:00:00 1995
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!uunet!in1.uu.net!news3.digex.net!access1.digex.net!rschifre
From: Richard Schifreen <rschifre@access1.digex.net>
Newsgroups: bionet.diagnostics
Subject: Help with FDLI Presentation
Date: Fri, 9 Jun 1995 09:04:31 -0400
Organization: Express Access Online Communications, USA
Lines: 32
Message-ID: <Pine.SUN.3.91.950609085340.7168A-100000@access1.digex.net>
NNTP-Posting-Host: access1.digex.net
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=US-ASCII

I have been asked to join a panel discussion at this year's Biologics 
Update sponsored by the Food and Drug Legal Institute and the American 
Bar Association.  The topic I've been asked to cover is "ancillary 
reagents" which CBER defines as being used in the manufacture or 
preparation of the biologic, but not a component of the biologic.  This 
might include cell culture media used to expand cells for ex vivo therapy 
or recombinant cytokines used in ex vivo therapy to modify cellular 
growth characteristics.  In general, CBER appears to be taking a 
reasonable approach to trying to make these reagents available for 
clinical research.

These "ancillary reagents" may also be viewed as devices and fall under 
the strict regulation of CDRH.  It is illegal to promote the use of a 
"device" for an application which is not included in its approved 
labelling.  The FDA typically requires manufacturers to perform due 
diligence that devices are not being promoted "off label."  This was the 
basis for taking the Centocor 19.9 test off the market and the recent 
changes in the labelling and approval of monoclonal antibodies used in 
immunopathology.  This is all despite the right of physicians to pretty 
much do as they please with respect to their own practice or hospital.

Can anyone help me with specifics.  I know there was a post here about a 
month ago on monoclonal antibodies which I didn't save - does anyone have 
a copy?  Does anyone have any specific examples which I could use in my 
presentation?

Best regards,
Rich Schifreen          phone: 301-840-4163
Life Technologies       fax:   301-670-1493
   E-Mail: rschifre@access.digex.net



From owner-diagnostics@net.bio.net Fri Jun 09 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!gatech!news.sprintlink.net!howland.reston.ans.net!vixen.cso.uiuc.edu!news.uoregon.edu!news.u.washington.edu!uw-beaver!cornellcs!travelers.mail.cornell.edu!newsstand.cit.cornell.edu!NewsWatcher!user
From: pts3@cornell.edu (phil)
Newsgroups: bionet.diagnostics
Subject: Help!! Paper Wasps Needed
Followup-To: bionet.diagnostics
Date: 7 Jun 1995 02:41:43 GMT
Organization: cornell
Lines: 24
Sender: pts3@cornell.edu (Verified)
Message-ID: <pts3-060695225048@132.236.236.185>
NNTP-Posting-Host: cu-dialup-0615.cit.cornell.edu

Hello.  My name is Phil Starks.  I am a graduate student at Cornell
University in the field of NeuroBiology and Behavior.  I am currently
examining paper wasps, specifically Polistes dominulus.  I am evaluating
their nesting behavior and population genetics.

I want to compare animals from different regions -- mostly from the
Northeast in areas between Boston, MA and Ithaca, NY.  My problem is
finding these critters.  They tend to congregate in the eves of man-made
structures.  I have searched state parks and some universities but have
only found 4 usable sites.  A usable site is one that has been relatively
undisturbed (not sprayed with insecticides) for a few years and contains 18
or more colonies.  

These wasps make un-enveloped nests -- you can plainly see the cells of the
comb (it looks much like a gray honeycomb).  P. dominulus  is the more
yellow and smaller of the 2 Polistes  species in this region (P. fuscatus 
is dark brown and the larger of the two animals).  At this time of year you
may see colonies with anywhere from 1 to 10 individuals, and nests that may
contain 8 to 100 cells.  If you know of any potential sites please email
me.  I am offering a $20.00 finder fee for useful sites.

Thanks for reading this message

Phil Starks (pts3@cornell.edu)

From owner-diagnostics@net.bio.net Sun Jun 11 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!Germany.EU.net!EU.net!news.sprintlink.net!sundog.tiac.net!cil.tiac.net!lynneb
From: lynneb@isotope.com (Lynne S. Batchelder)
Newsgroups: bionet.diagnostics
Subject: Re: Helicobacter sites
Date: Mon, 12 Jun 1995 13:55:40
Organization: Cambridge Isotope Laboratories
Lines: 11
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Message-ID: <lynneb.4.000DED97@isotope.com>
References: <199506121351.VAA32661@einstein.technet.sg>
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X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

In article <199506121351.VAA32661@einstein.technet.sg> pohyam@TECHNET.SG (Lim Pohyam) writes:
>From: pohyam@TECHNET.SG (Lim Pohyam)
>Subject: Helicobacter sites
>Date: 12 Jun 1995 06:52:19 -0700

>Does anyone know about URL sites for Helicobacter pylori? I would like to 
>know more about the treatment regime and serological diagnosis of the 
>bacterium, including ways of monitoring the serological profiles. 

I would also be interested in URL's for H. pylori. Any information would be 
helpful.

From owner-diagnostics@net.bio.net Sun Jun 11 23:00:00 1995
Path: biosci!TECHNET.SG!pohyam
From: pohyam@TECHNET.SG (Lim Pohyam)
Newsgroups: bionet.diagnostics
Subject: Helicobacter sites
Date: 12 Jun 1995 06:52:19 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 4
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NNTP-Posting-Host: net.bio.net

Does anyone know about URL sites for Helicobacter pylori? I would like to 
know more about the treatment regime and serological diagnosis of the 
bacterium, including ways of monitoring the serological profiles. 


From owner-diagnostics@net.bio.net Sun Jun 11 23:00:00 1995
Newsgroups: bionet.diagnostics
Path: biosci!bloom-beacon.mit.edu!usc!crash!kiehl
From: b3748@cts.com (Bryan Kiehl)
Subject: ROC Statistics
Organization: CTSNET
Date: Sun, 11 Jun 1995 23:26:00 GMT
Message-ID: <3rfu28$amc_001@kiehl.cts.com>
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I would like to find statistics programs for the Windows environment that 
include receiver-operator curve statistics. Does anyone know where these may 
be found?

Thanks!

Bryan Kiehl
GenBio
15222-A Avenue of Science
San Diego, CA 92128
(619) 592-9300, ext 309
(619) 592-9400 [FAX]

From owner-diagnostics@net.bio.net Mon Jun 12 23:00:00 1995
Path: biosci!rutgers!gatech!news.mathworks.com!news.ultranet.com!news.sprintlink.net!howland.reston.ans.net!math.ohio-state.edu!uwm.edu!newsspool.doit.wisc.edu!news.doit.wisc.edu!alpha.adp.wisc.edu!user
From: Fariello@doit.wisc.edu (Gabriele R. Fariello)
Newsgroups: bionet.immunology,bionet.diagnostics,sci.med.immunology,sci.bio.microbiology,sci.med
Subject: Information Wanted: EOSINOPHILIA
Date: Tue, 13 Jun 1995 14:35:43 -0500
Organization: UW
Lines: 14
Message-ID: <Fariello-1306951435430001@alpha.adp.wisc.edu>
NNTP-Posting-Host: alpha.adp.wisc.edu
Xref: biosci bionet.immunology:4494 bionet.diagnostics:151 sci.med.immunology:1769 sci.bio.microbiology:1078 sci.med:82122

would anyone with information on the diagnosis and treatment of
eosinophilia (hypereosinophilia)  Please forward that information, or a
decription of how to get to that information, to me. It would be GREATLY
appreciated.

Thanks

-- 
Gabriele (Guido) R. Fariello   |University of Wisconsin - Madison
                               |    Molecular Biology, Student
                               |Chemistry Curriculum Reform Effort,
                               |    Project Assistant
fariello@doit.wisc.edu         |Division of Information Technology,
fariello@students.wisc.edu     |    Computer Systems Engineering

From owner-diagnostics@net.bio.net Tue Jun 13 23:00:00 1995
Path: biosci!daresbury!sunsite.doc.ic.ac.uk!warwick!news.ncl.ac.uk!usenet
From: Roger Hayes <R.J.Hayes@ncl.ac.uk>
Newsgroups: bionet.diagnostics
Subject: Glutamate
Date: 14 Jun 1995 14:05:45 GMT
Organization: University of Newcastle
Lines: 3
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NNTP-Posting-Host: anaes18.ncl.ac.uk
Mime-Version: 1.0
X-Newsreader: WinVN 0.99.3

Anyone know a non HPLC method of measuring Glutamate in biological 
samples ? Cheers, Roger.


From owner-diagnostics@net.bio.net Tue Jun 13 23:00:00 1995
Path: biosci!U.WASHINGTON.EDU!rajs
From: rajs@U.WASHINGTON.EDU (Raj Shankarappa)
Newsgroups: bionet.diagnostics
Subject: single strand DNA-specific monoclonal antibody?
Date: 14 Jun 1995 09:04:43 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 21
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <v01510100ac04b83a0e0e@[128.95.235.6]>
NNTP-Posting-Host: net.bio.net

Is anyone aware of the availability of monoclonal antibody that binds
specifically to single stranded, but not double stranded DNA?  Please post
or reply directly.

Thank you in advance for the info.
-Raj.



* * * * * * * * * * * * * * * * * * * * * * * * * * *
Raj Shankarappa, Ph.D.
Univ of Washington School of Medicine
Microbiology 357740
Room K463 Health Sciences Building
Seattle WA 98195-7740
Tel: (206) 616-4282
Fax: (206) 616-1575
email: rajs@u.washington.edu
        



From owner-diagnostics@net.bio.net Tue Jun 13 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!news.sprintlink.net!uunet!worm.inch.com!usenet
From: ims@inch.com
Newsgroups: bionet.diagnostics
Subject: Diagnostic Kit Info Needed
Date: 14 Jun 1995 22:43:27 GMT
Organization: The Internet Channel
Lines: 15
Message-ID: <3rnomf$e5h@worm.inch.com>
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Hello,

I'm looking for some information on the size of the immunoassay 
diagnostic kit market in Latin American countries.  Test include 
pregnancy, HIV, ovulation, chlamydia, herpes, strep A and others.  
Countries include Mexico, Brazil, Peru, Colombia, Chile, and Costa Rica.

Any information is greatly appreciated.

Please email ims@inch.com

Best regards,

Scott Kushnick


From owner-diagnostics@net.bio.net Wed Jun 14 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!torn!uunet.ca!news.uunet.ca!inforamp.net!usenet
From: Ian Clarke <intermed@inforamp.net>
Newsgroups: bionet.diagnostics
Subject: Ortho PAP Stains
Date: 13 Jun 1995 14:03:43 GMT
Organization: InfoRamp Inc., Toronto, Ontario (416) 363-9100
Lines: 14
Message-ID: <3rk5rv$iau@inforamp.net>
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Hi everyone,

Inter Medico (Toronto) has recently purchased the exclusive world-wide 
rights for supply and distribution of Ortho PAP stains. The Ortho PAP 
stains are renowned for their superior stability and lot-to-lot 
consistency.

I am interested in getting in touch with companies who are interested in 
distributing these products in their home markets.

Ian




From owner-diagnostics@net.bio.net Wed Jun 14 23:00:00 1995
Path: biosci!sasa.gov.uk!odonnell
From: odonnell@sasa.gov.uk ("Kevin O'Donnell")
Newsgroups: bionet.diagnostics
Subject: Re: Ortho PAP Stains
Date: 15 Jun 1995 04:08:03 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 16
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <MAPI.Id.0016.00646f6e6e656c6c3132303130303137@MAPI.to.RFC822>
References: <3rk5rv$iau@inforamp.net>
NNTP-Posting-Host: net.bio.net

This is a commercial posting and therefore inappropriate for any of the =
bionet newsgroups (see the BIOSCI  faq at http://www.bio.net/).  My sugge=
sted home for commercial posts is the biz-bitotech list. You can subscrib=
e to this by sending the message: 

subscribe biz-biotech

to the address:

listserv@netcom.com

Hope this is helpful to anyone wishing to make posts of this kind.

Dr Kevin O'Donnell
co-discussion leader, bionet.diagnostics


From owner-diagnostics@net.bio.net Fri Jun 16 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!nic-nac.CSU.net!csulb.edu!info.ucla.edu!unixg.ubc.ca!port53.annex3.net.ubc.ca!garyd
From: garyd@unixg.ubc.ca (Gary C. Donaldson)
Newsgroups: bionet.diagnostics
Subject: pharmaceutical companies on the net
Date: Sat, 17 Jun 1995 15:51:42 UNDEFINED
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Anybody know of any pharmaceutical companies on the net?  Better still, how 
about one site with a list of them?  Thanks in advance.

Gary C. Donaldson
Dept. of Plant Science
University of British Columbia
garyd@unixg.ubc.ca


From owner-diagnostics@net.bio.net Sat Jun 17 23:00:00 1995
Path: biosci!ZEUS.DATASRV.CO.IL!ila2027
From: ila2027@ZEUS.DATASRV.CO.IL (Falk Fish)
Newsgroups: bionet.diagnostics
Subject: Re: single strand DNA-specific monoclonal antibody?
Date: 18 Jun 1995 15:02:03 -0700
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There should be plenty of those.  Search the literature.  Names that may 
be of high probability:

David(?) Stollar (USA)
Norman Staines (UK)
Dan Eilat (Israel)

And many others.


Falk Fish, Tel-Aviv, Israel.



From owner-diagnostics@net.bio.net Sat Jun 17 23:00:00 1995
Path: biosci!ZEUS.DATASRV.CO.IL!ila2027
From: ila2027@ZEUS.DATASRV.CO.IL (Falk Fish)
Newsgroups: bionet.diagnostics
Subject: Re: pharmaceutical companies on the net
Date: 18 Jun 1995 15:08:02 -0700
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Try http://www.promega.com


F. Fish


From owner-diagnostics@net.bio.net Sun Jun 18 23:00:00 1995
Path: biosci!bloom-beacon.mit.edu!usc!howland.reston.ans.net!news.sprintlink.net!demon!btnet!matsu.nis.co.jp!wnoc-tyo-news!wnoc-sfc-news!wnoc-kyo-news!news.csi.ad.jp!rerf!usenet
From: Chiyoko_Satoh@rerf.or.jp (Chiyoko Satoh)
Newsgroups: bionet.diagnostics
Subject: frequency ob hereditary non-polyposis colorectal cancer in Japanese or in Chinese?
Date: 19 Jun 1995 07:22:30 GMT
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Is there anyone who knows frequency of HNPCC in Japanese in Japan or
Japanese or oriental populations in western world?


         chiyoko satoh


From owner-diagnostics@net.bio.net Sun Jun 18 23:00:00 1995
Newsgroups: bionet.diagnostics
Path: biosci!bloom-beacon.mit.edu!usc!elroy.jpl.nasa.gov!swrinde!cs.utexas.edu!news.sprintlink.net!demon!plug.news.pipex.net!pipex!soap.news.pipex.net!pipex!edi.news.pipex.net!pipex!sasa.gov.uk!news
From: odonnell@sasa.gov.uk (Kevin O'Donnell)
Subject: Re: pharmaceutical companies on the net
Organization: Scottish Agricultural Science Agency
Date: Mon, 19 Jun 1995 16:22:14 GMT
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In article <garyd.12.00238095@unixg.ubc.ca>, garyd@unixg.ubc.ca 
(Gary C. Donaldson) says:
>
>
>Anybody know of any pharmaceutical companies on the net?  Better 
still, how 
>about one site with a list of them?  Thanks in advance.
>

Aside from Martin Leach's excellent site, try:

http://web.frontier.net/MEDMarket/indexes/indexmfr.html

and

http://www.gemini.co.uk/gemini/biopages/



Kevin O'Donnell
Scottish Agricultural Science Agency    
Edinburgh
Scotland                                           

From owner-diagnostics@net.bio.net Mon Jun 19 23:00:00 1995
Path: biosci!CAT.CCE.USP.BR!lpereira
From: lpereira@CAT.CCE.USP.BR (Lygia Pereira)
Newsgroups: bionet.diagnostics
Subject: microssatelites for paternity testing
Date: 20 Jun 1995 11:04:43 -0700
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Dear netters,

I would like to know which are the most used microsatelite markers 
for DNA fingerprinting using PCR (and silver staining).

In addition, does anybody know the references for the following markers?

	VWF1/F2
	D12-4815
	Y-27H39

Thanks a lot for the help,

L.Pereira, Ph.D.

From owner-diagnostics@net.bio.net Mon Jun 19 23:00:00 1995
Path: biosci!sasa.gov.uk!wood
From: wood@sasa.gov.uk (John Wood)
Newsgroups: bionet.diagnostics
Subject: unsubscribe
Date: 20 Jun 1995 01:32:13 -0700
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unsubscribe diagnost

John Wood
SASA
UK


From owner-diagnostics@net.bio.net Tue Jun 20 23:00:00 1995
Newsgroups: bionet.diagnostics
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!psgrain!agora!agora.rdrop.com!wayne
From: wayne@agora.rdrop.com (Wayne D. Rosenfield)
Subject: "Jewish" Genetic Diseases
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Date: Wed, 21 Jun 1995 22:01:05 GMT
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There is now a genetic disease mailing list, for discussions of diseases 
known to occur at an increased frequency among Jewish populations.
To subscribe, send email to the address: listproc@shamash.nysernet.org
with the message: subscribe genetic-disease <your name>

Wayne Rosenfield, Moderator
wayne@agora.rdrop.com


From owner-diagnostics@net.bio.net Wed Jun 21 23:00:00 1995
Path: biosci!POST.TAU.AC.IL!gynec9
From: gynec9@POST.TAU.AC.IL (Adam Sartiel)
Newsgroups: bionet.diagnostics
Subject: ALFexpress DNA sequencer
Date: 21 Jun 1995 23:59:54 -0700
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Hello,

I would like to have some information about the possible use of the 
Pharmacia ALF machines, especially the ALFexpress, for diagnostic and confirmatory 
sequence analysis. Is it actually preferrable to ABI's?

Adam Sartiel, M.Sc.
Department of Human Genetics
Sackler School of Medicine
Tel-Aviv University
Ramat-Aviv, ISRAEL
E-mail: gynec9@ccsg.tau.ac.il
Fax: 972-3-6407471


From owner-diagnostics@net.bio.net Thu Jun 22 23:00:00 1995
Path: biosci!VTH1.VTH.COLOSTATE.EDU!dgetzy
From: dgetzy@VTH1.VTH.COLOSTATE.EDU (David Getzy)
Newsgroups: bionet.diagnostics
Subject: Background staining in autoradiography.
Date: 22 Jun 1995 03:27:30 -0700
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Folks,

I have recently reviewed an autoradiography study for an experimental 
compound.  The control animals of the group received saline only.  In 
viewing the slides of the skin from the control animals, there is an 
increased deposition of silver grains between dermal collagen bundles.  
These spaces between collagen bundles are either processing artifacts or 
regions of cutaneous glycosaminoglycan accumulation.

Any thoughts on the non-specific deposition of silver grains in this area 
of skin (as well as increased non-specific deposition on hair shafts)?  
Is is possible that the high GAG content of these tissues would bind 
silver cations through electrostatic forces?

Thanks in advance for any help.

DMG

*********************************************************************
* Dave Getzy, Director                                              *
* Colo State Univ  Diagnostic Laboratories                          *
* 300 West Drake, Fort Collins, Co  80523                           * 
* PHONE 970-491-1281  FAX 970-491-0320                              *
* EMAIL dgetzy@vth1.vth.colostate.edu                               *
* http: //www.vth.colostate.edu                                     *
*********************************************************************


From owner-diagnostics@net.bio.net Thu Jun 22 23:00:00 1995
Path: biosci!OP1.UP.AC.ZA!CHIRG12
From: CHIRG12@OP1.UP.AC.ZA ("Dr A Goodhead")
Newsgroups: bionet.diagnostics
Subject: unsubscribe
Date: 23 Jun 1995 07:21:11 -0700
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unsubscribe diagnost

From owner-diagnostics@net.bio.net Thu Jun 22 23:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!news.moneng.mei.com!uwm.edu!uwvax!newssinet!news.u-tokyo.ac.jp!wnoc-tyo-news!wnoc-sfc-news!wnoc-kyo-news!news.csi.ad.jp!rerf!usenet
From: Chiyoko_Satoh@rerf.or.jp (Chiyoko Satoh)
Newsgroups: bionet.diagnostics
Subject: Frequency of HNPCC in Japanese?
Date: 22 Jun 1995 01:39:21 GMT
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Dear Dr.Perucho:

I sent a fax letter to you last night and this morning,but "error"  
returned.Is your fax no (619-535-5486,in USA) which was shown in 
your email is correct? If yuo give me yuor email adress,I greatly 
appreciate your kindness.
 
                                                csatoh


From owner-diagnostics@net.bio.net Thu Jun 22 23:00:00 1995
Path: biosci!VTH1.VTH.COLOSTATE.EDU!dgetzy
From: dgetzy@VTH1.VTH.COLOSTATE.EDU (David Getzy)
Newsgroups: bionet.diagnostics
Subject: Background staining in autoradiography. (fwd)
Date: 22 Jun 1995 03:29:16 -0700
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*********************************************************************
* Dave Getzy, Director                                              *
* Colo State Univ  Diagnostic Laboratories                          *
* 300 West Drake, Fort Collins, Co  80523                           * 
* PHONE 970-491-1281  FAX 970-491-0320                              *
* EMAIL dgetzy@vth1.vth.colostate.edu                               *
* http: //www.vth.colostate.edu                                     *
*********************************************************************

---------- Forwarded message ----------
Date: Thu, 22 Jun 1995 04:27:31 -0600 (MDT)
From: David Getzy <dgetzy@vth1.vth.colostate.edu>
To: diagnost@bio.net
Subject: Background staining in autoradiography.


Folks,

I have recently reviewed an autoradiography study for an experimental 
compound.  The control animals of the group received saline only.  In 
viewing the slides of the skin from the control animals, there is an 
increased deposition of silver grains between dermal collagen bundles.  
These spaces between collagen bundles are either processing artifacts or 
regions of cutaneous glycosaminoglycan accumulation.

Any thoughts on the non-specific deposition of silver grains in this area 
of skin (as well as increased non-specific deposition on hair shafts)?  
Is is possible that the high GAG content of these tissues would bind 
silver cations through electrostatic forces?

Thanks in advance for any help.

DMG

*********************************************************************
* Dave Getzy, Director                                              *
* Colo State Univ  Diagnostic Laboratories                          *
* 300 West Drake, Fort Collins, Co  80523                           * 
* PHONE 970-491-1281  FAX 970-491-0320                              *
* EMAIL dgetzy@vth1.vth.colostate.edu                               *
* http: //www.vth.colostate.edu                                     *
*********************************************************************



From owner-diagnostics@net.bio.net Fri Jun 30 23:00:00 1995
Path: biosci!agate!howland.reston.ans.net!news.sprintlink.net!news.clark.net!usenet
From: systems@khem.com (bob diggs)
Newsgroups: bionet.diagnostics
Subject: SOFTWARE: Chemical Inventory/Waste Management/Material  Safety Data
Date: 1 Jul 1995 15:52:56 GMT
Organization: khem products incorporated
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If you are interested in the following -
    
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THEN YOU SHOULD VISIT OUR WEB HOME PAGE!!!
  
URL  :  http://www.khem.com/khem/home.html
EMAIL:  info@khem.com
  
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


