From owner-diagnost@hgmp.mrc.ac.uk Tue May 2 13:10:40 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 5A2C517AC3; Tue, 2 May 2000 13:10:38 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 4F21417B18; Tue, 2 May 2000 13:06:35 +0100 (BST) To: diagnost@net.bio.net Newsgroups: bionet.diagnostics From: owner-diagnost@hgmp.mrc.ac.uk Subject: Need the plasmid containing the sequence for CR1 Message-Id: <20000502120635.4F21417B18@mercury.hgmp.mrc.ac.uk> Date: Tue, 2 May 2000 13:06:35 +0100 (BST) Sender: owner-diagnost@hgmp.mrc.ac.uk Precedence: bulk Status: RO Good days, everybody , I have a question : Why there is not transgenic pigs expressing human CR1 to Overcome complement-mediated hyperacute xenograft rejection ? CR1 has extrinsic activity , i.e., it inactivates convertases assembled on external membranes, and it also exhibits intrinsic activity ,i.e., it inactivates convertases formed on the same membrane on which it is expressed. Among the members of the RCA family , CR1 is the only one that possesses dcay-accelerating activity for both C3 and C5 convertases in both the classical and alternative pathways,as well as factor I cofactor activity for the degradation of both C3b and C4b . Would you please send me the plasmid containing the sequence for CR1 ? Department of immunology The Third Military Medical University Gao tanyan,Sha pingba Chongqing , 400038 People's Republic of China. Guo Bo E-mail: immuno06@mail.tmmu.com.cn --- From owner-diagnost@hgmp.mrc.ac.uk Tue May 2 13:15:42 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id EB3B617B31; Tue, 2 May 2000 13:10:42 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 958F117B1A; Tue, 2 May 2000 13:07:35 +0100 (BST) To: diagnost@net.bio.net Newsgroups: bionet.diagnostics From: daemon@hgmp.mrc.ac.uk, [mailto:daemon@hgmp.mrc.ac.uk]@hgmp.mrc.ac.uk, On@hgmp.mrc.ac.uk, Behalf@hgmp.mrc.ac.uk, Of@hgmp.mrc.ac.uk Subject: Need the plasmid containing the sequence for CR1 Message-Id: <20000502120735.958F117B1A@mercury.hgmp.mrc.ac.uk> Date: Tue, 2 May 2000 13:07:35 +0100 (BST) Sender: owner-diagnost@hgmp.mrc.ac.uk Precedence: bulk Status: RO Good days, everybody , I have a question : Why there is not transgenic pigs expressing human CR1 to Overcome complement-mediated hyperacute xenograft rejection ? CR1 has extrinsic activity , i.e., it inactivates convertases assembled on external membranes, and it also exhibits intrinsic activity ,i.e., it inactivates convertases formed on the same membrane on which it is expressed. Among the members of the RCA family , CR1 is the only one that possesses dcay-accelerating activity for both C3 and C5 convertases in both the classical and alternative pathways,as well as factor I cofactor activity for the degradation of both C3b and C4b . Would you please send me the plasmid containing the sequence for CR1 ? Department of immunology The Third Military Medical University Gao tanyan,Sha pingba Chongqing , 400038 People's Republic of China. Guo Bo E-mail: immuno06@mail.tmmu.com.cn --- From owner-diagnost@hgmp.mrc.ac.uk Tue May 2 16:53:14 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 5BB7117B2A; Tue, 2 May 2000 16:53:12 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 5D36217AE9; Tue, 2 May 2000 16:53:05 +0100 (BST) To: diagnost@net.bio.net Newsgroups: bionet.diagnostics From: daemon@hgmp.mrc.ac.uk, [mailto:daemon@hgmp.mrc.ac.uk]@hgmp.mrc.ac.uk, On@hgmp.mrc.ac.uk, Behalf@hgmp.mrc.ac.uk, Of@hgmp.mrc.ac.uk Subject: apologies to diagnost Message-Id: <20000502155305.5D36217AE9@mercury.hgmp.mrc.ac.uk> Date: Tue, 2 May 2000 16:53:05 +0100 (BST) Sender: owner-diagnost@hgmp.mrc.ac.uk Precedence: bulk Hi all, I have recently taken over the moderation of the diagnost newsgroup and in my enthusiasm to forward messages to the newsgroup forwarded a list of diagnost recipient email addresses to the group. This list was intended for administration use only and I apologise for making it public. I have contacted Bionet support and they have cancelled the message from the webpages and have attempted to recall the original posting. Sorry once again. Robert Burns Antibody Unit SASA Craigs Road Edinburgh EH12 8NJ burns@sasa.gov.uk --- From owner-diagnost@hgmp.mrc.ac.uk Fri May 5 09:25:33 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 21CBE17AA8; Fri, 5 May 2000 09:25:33 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id C4ED317A96; Fri, 5 May 2000 09:25:31 +0100 (BST) To: diagnost@net.bio.net Newsgroups: bionet.diagnostics From: custom@abcam.com, [mailto:custom@abcam.com]@hgmp.mrc.ac.uk Subject: 2-in-1 custom antibodies Message-Id: <20000505082531.C4ED317A96@mercury.hgmp.mrc.ac.uk> Date: Fri, 5 May 2000 09:25:31 +0100 (BST) Sender: owner-diagnost@hgmp.mrc.ac.uk Precedence: bulk Abcam has introduced a new 2-in-1 custom antibody production service that increases the chances of your peptide antibodies recoginising your target protein. For further details please go to: http://www.abcam.com/public/fs_base.cfm?sp=antibody_production.cfm which outlines our custom antibody services. Thinking of your new wardrobe for the summer? If you recommend us to a friend who orders a custom antibody project from Abcam, then you and your friend will both receive one of Abcam's phenomonally popular t-shirts. Good luck with your research. Best regards, Mark Abcam Marketing Department http://www.abcam.com ************************************************** abcam.com - the world's antibody gateway ************************************************** ------------------------------------ * Abcam is against spamming and will only contact you when we have information we genuinely believe will benefit you * To be removed from the Abcam mailing list simply return this email with 'remove' in the subject header ------------------------------------ [ref23622:4-May-2000] From owner-diagnost@hgmp.mrc.ac.uk Thu May 11 12:27:44 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id D781117AAB; Thu, 11 May 2000 12:27:43 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id A3E9E17A4E; Thu, 11 May 2000 12:27:41 +0100 (BST) To: diagnost@net.bio.net Newsgroups: bionet.diagnostics From: daemon@hgmp.mrc.ac.uk, [mailto:daemon@hgmp.mrc.ac.uk]@hgmp.mrc.ac.uk, On@hgmp.mrc.ac.uk, Behalf@hgmp.mrc.ac.uk, Of@hgmp.mrc.ac.uk Subject: unmoderated messages Message-Id: <20000511112741.A3E9E17A4E@mercury.hgmp.mrc.ac.uk> Date: Thu, 11 May 2000 12:27:41 +0100 (BST) Sender: owner-diagnost@hgmp.mrc.ac.uk Precedence: bulk Hi, It has been brought to my attention that junk messages are making their way onto diagnost without being moderated by me. I have contacted bionet admin to see if we can fix this. Robert Burns Antibody Unit SASA Craigs Road Edinburgh EH12 8NJ burns@sasa.gov.uk ---