From owner-embldatabank@net.bio.net Thu Aug 11 23:00:00 1994
Path: biosci!internet!biosci!not-for-mail
From: kristoff (David Kristofferson)
Newsgroups: bionet.molbio.embldatabank
Subject: UNSUBSCRIBING, BIOSCI ARCHIVES, ADDRESS DATABASE & BIOSCI FAQ
Date: 12 Aug 1994 02:02:17 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 322
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199408120900.CAA09936@net.bio.net>
NNTP-Posting-Host: net.bio.net


Four important items follow: How to cancel e-mail subscriptions to
BIOSCI newsgroups, BIOSCI archive searching, the BIOSCI FAQ, and the
BIOSCI User Address Directory form.  If you have not yet listed
yourself in our BIOSCI user directory, please take a few minutes to
complete and return the form below.  If your personal information has
changed since you listed yourself, please send us a complete new
updated form.  We can not make manual revisions to existing entries.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net



	 **** How to cancel a BIOSCI e-mail subscription ****

If you want to cancel your e-mail subscription to this group, 
PLEASE DO NOT POST YOUR UNSUBSCRIBE REQUEST TO THE NEWSGROUP ADDRESS
(NOR REPLY TO A MESSAGE POSTED TO THE NEWSGROUP)!!!

This would send your request to all of the readers of the newsgroup,
but it might still not be seen by the BIOSCI staff - thus you would
annoy many people and possibly not accomplish your goal anyway.

IF YOU ARE LOCATED IN THE AMERICAS OR PACIFIC RIM COUNTRIES, please
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Instructions will be returned automatically, so the contents of your
message do not matter.

IF YOU ARE LOCATED IN EUROPE, AFRICA OR CENTRAL ASIA, please send a
message to

MXT@dl.ac.uk

containing the word 

help

in the body of the message to retrieve e-mail server instructions.
Any text placed on the Subject: line of your message will be ignored,
so be sure to put the "help" command in the body of the message.

If you need personal assistance, a BIOSCI staff member can be
contacted at either of the following addresses.  Please contact the
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Support Address                      Location
---------------                      --------
biosci@daresbury.ac.uk               Europe, Africa, and Central Asia
biosci-help@net.bio.net              Americas and the Pacific Rim


		 **** SEARCHING BIOSCI ARCHIVES ****

The easiest way to search the BIOSCI archives is to use gopher
software and connect over the Internet to net.bio.net, the U.S. BIOSCI
computer.  We maintain three indexes which are searchable from the
main gopher menu on net.bio.net: (1) an index of all BIOSCI postings;
(2) an index of individual journal article references from the Table
of Contents postings on the BIO-JOURNALS newsgroup; and (3) an index
of BIOSCI users including regular mail and e-mail addresses, phone/FAX
numbers, research interests, and newsgroup participation.

E-mail users can search the BIOSCI archives by using our waismail
e-mail server.  For instructions send the message

help

to waismail@net.bio.net.  Leave the Subject: line blank (anything
entered on the Subject: line is ignored).

WAIS software can also be used to search the archives as described in
the BIOSCI FAQ (see below).

Finally, the BIOSCI archive files are accessible by anonymous FTP to
net.bio.net [134.172.2.69] in the directory pub/BIOSCI.


       **** BIOSCI FREQUENTLY ASKED QUESTIONS (FAQ) SHEET ****

New users of BIOSCI/bionet may want to read the "Frequently Asked
Questions" or "FAQ" sheet for BIOSCI.  The FAQ provides details on how
to participate in these forums and is available for anonymous FTP from
net.bio.net [134.172.2.69] in pub/BIOSCI/doc/biosci.FAQ or for
retrieval by gopher to net.bio.net, port 70.  It may also be requested
by sending the command

info faq

in the body of an e-mail message to the Internet address
biosci-server@net.bio.net.  Please do not enter the info faq command
on the Subject: line of your message since the e-mail server ignores
text on the Subject: line.

The FAQ is also posted on the first of each month to the newsgroup
BIONEWS/bionet.announce immediately following the posting of the
BIOSCI information sheet.


	       **** BIOSCI USER ADDRESS DIRECTORY ****

Please take this opportunity to add your name and address information
to the BIOSCI User Address Database if you have not already done so.

Below is the address form that we would like each reader of the
BIOSCI/bionet newsgroups to complete and return if you would like to
be listed in our database.  The database serves as a directory that
enables biologists, who are currently using (or even just reading) the
BIOSCI newsgroups, to look up e-mail addresses and other information
about our users.

The address database is reindexed nightly for WAIS, waismail, and
gopher access.  If you have access to gopher, connect to net.bio.net
to search the database.  If you have access to WAIS, please use our
WAIS source biologists-addresses.src.  If you are not on the Internet,
please use our waismail server (send the word "help" to
waismail@net.bio.net to get instructions; any text on the Subject:
line of your message will be ignored, so put the help command in the
body of the mail message.).

Please carefully follow the instructions for completing the form
below and return it to either of the following two addresses
(whichever is more convenient for you).  Thanks in advance for taking
the time to complete and return the form.

Addresses for returning forms         Location        Network
-----------------------------         --------        -------
biovote@net.bio.net                   U.S.A.          Internet/BITNET
biovote@daresbury.ac.uk               U.K.            JANET


	     MAKING SURE THAT YOUR INFORMATION IS CURRENT

This notice will be mailed bimonthly to each newsgroup.  You should
check your database entry from time-to-time to see if your address
information is still up-to-date.


		  Using Gopher to complete the form
                  ---------------------------------

If you don't want to use a text editor, you can also use Dan
Jacobson's gopher site to fill out the address database form as
follows.  Otherwise skip this section on gopher and proceed to the
instructions for filling out the form below.

> To add yourself to the database just point your
> gopher client at merlot.gdb.org and select the following:
> 
> -->  15. Searching For Biologists/
> 
>  -->  9.  E-mail Addresses of Biosci-Bionet Users/
> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

> Europeans can point their gopher client at gopher.csc.fi and add their
> information to the database. All entries will be mailed directly to
> Dave for incorporation in a wais source.
> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


	    IMPORTANT INSTRUCTIONS - PLEASE READ CAREFULLY

Please enter all responses after the : on each line, leaving one (1)
blank space after the : (i.e., before the start of your text).

Please do NOT extend your responses past the end of each line (80
characters).

PLEASE DO NOT alter any of the field identifiers such as "first name: ". 
If you have nothing to enter after a field identifier, PLEASE LEAVE IT
- do not delete it even if there is no data on the line in question.

Several lines are provided at the end of the form for comments, but,
please adhere to the line length restriction.

On the date: line, please enter the date in the DD-MM-YY format, e.g.,
15-05-93 for 15 May 1993.  This line will tell others when the
information was last updated.  Please be sure to include the 0's for
single digit days or months, e.g., 15-05-93, not 15-5-93.

Note that the "e-mail network: " line below is for specifying, e.g.,
"Internet," "BITNET," "EARN," "JANET," or whatever other network that
your computer may be on.

If you are uncertain about any field, please feel free to leave it
blank, but please DO NOT DELETE the field identifier from the form!

In the first field below, "New information or Update ...", please
enter "N" if this is the first time that you have registered in the
directory or "U" if you are correcting a listing that you sent to us
previously.

The comment: lines may be used for anything that you like but PLEASE
DO NOT DELETE THEM FROM THE FORM OR ALTER THEM.  One suggested use is
to list the names of the newsgroups in which you participate.  Please
use the MAILING LIST name (see below - the latest version of the list
can be requested from biosci@net.bio.net) instead of the USENET name
even if you don't participate by e-mail.  WAIS might get confused by
the periods in the USENET names.  This allows one to retrieve via WAIS
or waismail the list of participants in a particular group.

For example:

comment: ARABIDOPSIS PLANT-BIOLOGY BIONEWS

On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIOPHYSICAL-SOCIETY        bionet.prof-society.biophysics
BIOPHYSICS                 bionet.biophysics
BIO-SOFTWARE               bionet.software
BIOTHERMOKINETICS          bionet.metabolic-reg
CELL-BIOLOGY               bionet.cellbiol
CHLAMYDOMONAS              bionet.chlamydomonas
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
CYTONET                    bionet.cellbiol.cytonet
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
GRASSES-SCIENCE            bionet.biology.grasses
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
MYCOLOGY                   bionet.mycology
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PARASITOLOGY               bionet.parasitology
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
PROTISTA                   bionet.protista
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
STRUCTURAL-NMR             bionet.structural-nmr
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

Listing newsgroups on the comment: line is optional, of course.

Thanks again for your cooperation!



--------------- please cut here and return portion below ---------------

New information or Update to old record (enter N or U): 
date (DD-MM-YY): 
first name: 
middle initial: 
family name: 
job title: 
e-mail address: 
e-mail network: 
phone number: 
FAX number: 
institution: 
address1: 
address2: 
address3: 
city: 
state/province: 
country: 
postal code: 
research interest: 
research interest: 
comment: 
comment: 
comment: 
comment: 
comment: 


From owner-embldatabank@net.bio.net Thu Aug 11 23:00:00 1994
Path: biosci!rutgers!gatech!howland.reston.ans.net!pipex!lyra.csx.cam.ac.uk!doc.ic.ac.uk!charlie.lif.icnet.uk!news.lif.icnet.uk!alex
From: alex@darwin.lif.icnet.uk (Alex Whittaker - BIU)
Newsgroups: bionet.molbio.embldatabank
Subject: EMBL locus name to Accession Number
Date: 12 Aug 1994 14:55:54 GMT
Organization: Imperial Cancer Research Fund
Lines: 31
Distribution: world
Message-ID: <ALEX.94Aug12145554@darwin.lif.icnet.uk>
NNTP-Posting-Host: darwin.lif.icnet.uk


  Hi, I am trying to make a small GCG database containing all sequence
 entries described in the eukaryote promoter database (EPD). I have pulled
 out 60% of the sequences from our GenBank databases, unfortunately however,
 the remainder have EMBL locus names not common with the genbank entries in
 our local sets.

  What would solve this problem would be a utility to change EMBL locus
 names into accession numbers, or a database retrieval program into which I
 can feed a file of 1200 locus names.

  Regards, 


  Alex Whittaker                         ______  \||/_
                                        |      |  oo \   "All I know
  Biomedical Informatics Unit           |      |   L_     is that I know
  Imperial Cancer Research Fund         |______|    \/    nothing"
  London                                ________    |
                                       [========]  /
  alex@bison.lif.icnet.uk                     ---OOO-
                                             |ooooooo|
--
  Alex Whittaker                         ______  \||/_
                                        |      |  oo \   "All I know
  Biomedical Informatics Unit           |      |   L_     is that I know
  Imperial Cancer Research Fund         |______|    \/    nothing"
  London                                ________    |
                                       [========]  /
  alex@bison.lif.icnet.uk                     ---OOO-
                                             |ooooooo|

From owner-embldatabank@net.bio.net Wed Aug 17 23:00:00 1994
Path: biosci!agate!doc.ic.ac.uk!daresbury!not-for-mail
From: Paul Britton <paul.britton@afrc.ac.uk> (Tel \(44\) \(0\)635 578411)
Newsgroups: bionet.molbio.embldatabank
Subject: How to access Geneseq Database
Date: 18 Aug 1994 17:15:38 +0100
Lines: 31
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <3301fa$sb2@mserv1.dl.ac.uk>
Sensitivity: Company-Confidential
Original-To: virology@dl.ac.uk (Receipt Notification Requested) (Non Receipt Notification Requested) (Reply Requested),
 embl-database@dl.ac.uk (Receipt Notification Requested) (Non Receipt Notification Requested) (Reply Requested)


------------------------------ Start of body part 1

Hi
I would like to obtain a copy of a sequence from the Geneseq Database. An
accession number was cited in a recent paper. Any help would be appreciated.

Cheers

Paul Britton

------------------------------ Start of body part 2

*******************************************************************************
*  Paul Britton                   |   Tel : (44) 635 577268                   *
*  Division of Molecular Biology  |   Fax : (44) 635 577263                   *
*  Institute for Animal Health    | Janet : Paul.Britton@bbsrc.ac.uk          *
*  Compton Laboratory             | X.400 : G=Paul; S=Britton; O=BBSRC;       *
*  Compton                        |         P=uk.ac; C=GB                     *
*  Newbury, Berkshire             |                                           *
*  RG16 0NN, UK                   |                                           *
*                                 |                                           *
*   // \\          // \\  // \\          // \\  // \\          // \\  // \\   *
*      | \\      // | :,\\': | \\      // | :,\\': | \\      // | :,\\': | \\ *
*      | | \\  // | | //  \\ | | \\  // | | //  \\ | | \\  // | | //  \\ | |  *
*     \\ | :,\\': | //      \\ | :,\\': | //      \\ | :,\\': | //      \\ |  *
*       \\ //  \\ //          \\ //  \\ //          \\ //  \\ //          \\  *
*******************************************************************************


------------------------------ End of body part 2

From owner-embldatabank@net.bio.net Thu Aug 18 23:00:00 1994
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!stoehr
From: stoehr@embl-heidelberg.de (Peter Stoehr)
Newsgroups: bionet.molbio.embldatabank
Subject: Re: How to access Geneseq Database
Message-ID: <1994Aug19.203038.171492@eros.embl-heidelberg.de>
Date: 19 Aug 94 20:30:38 +0100
References: <3301fa$sb2@mserv1.dl.ac.uk>
Distribution: bionet
Organization: European Molecular Biology Laboratory
Lines: 17

In article <3301fa$sb2@mserv1.dl.ac.uk>, Paul Britton <paul.britton@afrc.ac.uk> (Tel \(44\) \(0\)635 578411) writes:
> 
> Hi
> I would like to obtain a copy of a sequence from the Geneseq Database. An
> accession number was cited in a recent paper. Any help would be appreciated.
> 
Paul,
GeneSeq is a database of sequences extracted from the patent literature which
is commercial product of Intelligenetics & Derwent. You either have to buy
the database, or hope some kind soul who already has will send you the sequence.

If the article happened to quote the patent number, we might be able to find
it here.

Regards,
Peter Stoehr
EMBL Data Library

From owner-embldatabank@net.bio.net Sat Aug 20 23:00:00 1994
Path: biosci!agate!usenet.ins.cwru.edu!news.ecn.bgu.edu!psuvax1!news.pop.psu.edu!news.cac.psu.edu!news.tc.cornell.edu!travelers.mail.cornell.edu!newsstand.cit.cornell.edu!NewsWatcher!user
From: cc37@cornell.edu (CC)
Newsgroups: bionet.molbio.embldatabank
Subject: protein info??
Followup-To: bionet.molbio.embldatabank
Date: 21 Aug 1994 22:05:10 GMT
Organization: Cornell University
Lines: 10
Sender: cc37@cornell.edu (Verified)
Message-ID: <cc37-210894180718@132.236.171.160>
NNTP-Posting-Host: 132.236.171.160

Hi --
      Do there exist databases that have information such as secondary &
tertiary structures, active sites, mutations that disrupt function, etc.,
for highly-conserved proteins?  I am particularly interested in ATP
synthase FO subunits, cytochrome c oxidase subunits, and other H+
pore-forming proteins.  So far I've just been searching through the
literature, and if I could access fairly complete information on line, this
would be a great leap forward for my dissertation.  Any help is
appreciated, and please send e-mail to cc37@cornell.edu.  Thanks!
                                                                      -- CC

From owner-embldatabank@net.bio.net Mon Aug 22 23:00:00 1994
Newsgroups: bionet.molbio.embldatabank
Path: biosci!agate!howland.reston.ans.net!EU.net!sunic!news.lth.se!news.lu.se!bosse-q840.wblab.lu.se!Bo.Servenius
From: Bo Servenius <Bo.Servenius@wblab.lu.se>
Subject: Size and release info for EMBL 39
Message-ID: <1994Aug23.142956.18693@nomina.lu.se>
X-Xxmessage-Id: <AA7FD34AEE013821@bosse-q840.wblab.lu.se>
X-Xxdate: Tue, 23 Aug 94 16:24:42 GMT
Sender: news@nomina.lu.se (USENET News System)
Nntp-Posting-Host: bosse-q840.wblab.lu.se
Organization: Lund university, Sweden
X-Useragent: Version 1.1.3
Date: Tue, 23 Aug 1994 14:29:56 GMT
Lines: 7

Dear Netters:

Could ylu please point me to info about the size and releasedate of EMBL v39.

yours

BOSSE

From owner-embldatabank@net.bio.net Mon Aug 22 23:00:00 1994
Newsgroups: bionet.molbio.embldatabank
Path: biosci!agate!doc.ic.ac.uk!daresbury!bioftp.unibas.ch!doelz
From: doelz@comp.bioz.unibas.ch (Reinhard Doelz)
Subject: Re: Size and release info for EMBL 39
Message-ID: <1994Aug23.153006.5298@comp.bioz.unibas.ch>
Organization: EMBnet Switzerland [Basel]
X-Newsreader: TIN [version 1.2 PL2]
References: <1994Aug23.142956.18693@nomina.lu.se>
Date: Tue, 23 Aug 1994 15:30:06 GMT
Lines: 91

Bo Servenius (Bo.Servenius@wblab.lu.se) wrote:
: Could ylu please point me to info about the size and releasedate of EMBL v39.

As always, it is on bioftp.unibas.ch in one of the root menu items: 


                  EMBnet BioInformation Resource (Switzerland)

      1.  About Gopher, and this bioftp site/
      2.  Biology subject tree in Gopher/
      3.  DIBUG [Discover Insight Biosym User Group] Mailing list/
 -->  4.  EMBNet BioInformation Resource Switzerland/
      5.  GCG Software Manual/
      6.  Infoservers in European Countries/
      7.  and if you have suggestions or problems....  [ 7Jan94, 1kb].
      8.  development site of GOPHER (U Minnesota)/
      9.  selected USENET News/


      1.  About EMBnet/
 -->  2.  Database/
      3.  Hints/
      4.  Info on this EMBNet Information Resource  [ 7Jan94, 4kb].
      5.  Other EMBnet Hosts and Sources of Information/
      6.  Software/

      1.  About these searches  [18Jan94, 1kb].
 -->  2.  EMBL/
      3.  EMBL updates/
      4.  Experimental/
      5.  GENBANK (Indiana)/
      6.  Genomes/
      7.  More DNA searches/
      8.  Protein databases (NIH)/
      9.  general database searches (HOPKINS)/


 -->  1.  Release Notes  [27Jun94, 22kb].
      2.  Search in all EMBL data (last release on CD)             <?>


Excerpts: 

                               EMBL Data Library
                          Nucleotide Sequence Database
                                 Release Notes
                             Release 39, June 1994

...



The EMBL nucleotide sequence database was frozen to make Release 39 on 6th  June1994.   The  release  contains  182,615  sequence entries comprising 192,195,819nucleotides.  This represents an increase of about 8% over  Release  38.   Thesefigures  do  not  include data in the file which contains patent data which havenot yet been fully integrated into the database.  A breakdown of Release  39  bytaxonomic division is shown below:
                  Division             Entries    Nucleotides
                  -----------------    -------    ------------
                  Bacteriophage            991         1343992
                  ESTs                   35353        11177758
                  Fungi                   6639        13114445
                  Invertebrates          11705        20310436
                  Organelles              6071         7682925
                  Other Mammals           5138         6027529
                  Other Vertebrates       5931         6924533
                  Plants                  9030        11350492
                  Primates               29014        30287388
                  Prokaryotes            17640        30484972
                  Rodents                20793        23422518
                  STSs                    5346         1626193
                  Synthetic               6463         3317705
                  Unclassified            5429         3650188
                  Viruses                17072        21474745
                  -----------------    -------    ------------
                  Total                 182615       192195819

                  plus:
                  Other patents           3268          951445
                  -----------------    -------    ------------
                  Grand Total           185883       193147264




regards
Reinhard 



-- 
  +---------------------------+-------------------------------------------+
  |    Dr. Reinhard Doelz     | Tel. x41 61 2672247    Fax x41 61 2672078 |
  |      Biocomputing         | electronic Mail       doelz@urz.unibas.ch |
  |Biozentrum der Universitaet+-------------------------------------------+

From owner-embldatabank@net.bio.net Tue Aug 23 23:00:00 1994
Path: biosci!bcm!gazette.bcm.tmc.edu!rsmith
From: rsmith@dot.bcm.tmc.edu (Randall Smith)
Newsgroups: bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Subject: BCM Sequence Annotation Web Server
Date: 24 Aug 1994 11:14:20 GMT
Organization: Institute for Molecular Genetics, Baylor College of Medicine
Lines: 64
Distribution: world
Message-ID: <RSMITH.94Aug24061420@dot.bcm.tmc.edu>
NNTP-Posting-Host: dot.imgen.bcm.tmc.edu
Xref: biosci bionet.molbio.genbank:1717 bionet.molbio.embldatabank:357 bionet.molbio.genome-program:911 bionet.molbio.proteins:2518


   Announcing a new WWW Server: The BCM Sequence Annotation Server

URL:  http://dot.imgen.bcm.tmc.edu:9331/seq-annot/home.html

Developed by Kanwal Gill, Brent Wiese, and Randall Smith
Human Genome Center, Baylor College of Medicine, Houston TX  USA


We have created a "Sequence Annotation" WWW Server that allows
researchers to add their own annotations to Entrez (NCBI) DNA and
protein sequence reports.  Our Annotation Server is intended as a
method for investigators to easily share new information about
sequences, e.g., new features, interesting sequence matches, domain
identifications, etc.

A user who wishes to make an annotation for an Entrez sequence will be
given the chance to select an annotation type (eg coding region,
variant, etc.). The user is then requested to enter a short annotation
that will appear as an embedded link in an Entrez report.  The
annotator will then be prompted to enter an extended commentary which
gives the further details about the annotation. The annotator may also
enter some keywords that can be searched on and URL's that will lead
to more information (eg, an entry in another database, a file of data
on the annotator's home computer, etc).

Only the annotations themselves are stored on our local server. When a
user wishes to view an annotated record, our server requests a
sequence report from the NCBI Entrez Server. The local annotations are
then embedded within the returned report.

As an initial entry, we have added several hundred annotations based
on data kindly provided by Keith Robison.  The annotations list
probable coding regions within bacterial sequences that are not
annotated as such in GenBank (see Table 2 of K. Robison, W. Gilbert
and G.M. Church, "Large scale bacterial gene discovery by similarity
search", Nature Genetics 7:205, 1994).

We invite the biological community to use the server to view this data
as well as to add data of their own.  Users wishing to view the data
need only the URL listed above and a graphical WWW browser such as
Mosaic or Chimera.  Users wishing to add data would be well-advised to
also prepare the text of their annotation and extended commentary as
well as to have their URL's (if any) in mind before beginning.
Extensive on-line help is provided for both types of users.

Suggestions and comments regarding how the server can best meet the
needs of the biological community are welcome.  There is a comments
form provided in the server for typing in your comments.  Comments may
also be emailed to Randall Smith at rsmith@bcm.tmc.edu.



------------------------------------------------------------------------
Randall F. Smith
Human Genome Center
Department of Molecular and Human Genetics and
W.M. Keck Center for Computational Biology
Baylor College of Medicine
Houston, TX  77030  USA

rsmith@bcm.tmc.edu
713-798-4735; FAX: 713-798-5386
------------------------------------------------------------------------

From owner-embldatabank@net.bio.net Tue Aug 23 23:00:00 1994
Path: biosci!biosci!not-for-mail
From: rsmith@DOT.IMGEN.BCM.TMC.EDU (Randall Smith)
Newsgroups: bionet.announce,bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Subject: BCM Sequence Annotation Web Server
Date: 24 Aug 1994 12:54:21 -0700
Organization: Institute for Molecular Genetics, Baylor College of Medicine
Lines: 63
Sender: kristoff@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: world
Message-ID: <RSMITH.94Aug22133942@dot.bcm.tmc.edu>
NNTP-Posting-Host: net.bio.net
Xref: biosci bionet.announce:1371 bionet.molbio.genbank:1721 bionet.molbio.embldatabank:358 bionet.molbio.genome-program:912 bionet.molbio.proteins:2523

   Announcing a new WWW Server: The BCM Sequence Annotation Server

URL:  http://dot.imgen.bcm.tmc.edu:9331/seq-annot/home.html

Developed by Kanwal Gill, Brent Wiese, and Randall Smith
Human Genome Center, Baylor College of Medicine, Houston TX  USA


We have created a "Sequence Annotation" WWW Server that allows
researchers to add their own annotations to Entrez (NCBI) DNA and
protein sequence reports.  Our Annotation Server is intended as a
method for investigators to easily share new information about
sequences, e.g., new features, interesting sequence matches, domain
identifications, etc.

A user who wishes to make an annotation for an Entrez sequence will be
given the chance to select an annotation type (eg coding region,
variant, etc.). The user is then requested to enter a short annotation
that will appear as an embedded link in an Entrez report.  The
annotator will then be prompted to enter an extended commentary which
gives the further details about the annotation. The annotator may also
enter some keywords that can be searched on and URL's that will lead
to more information (eg, an entry in another database, a file of data
on the annotator's home computer, etc).

Only the annotations themselves are stored on our local server. When a
user wishes to view an annotated record, our server requests a
sequence report from the NCBI Entrez Server. The local annotations are
then embedded within the returned report.

As an initial entry, we have added several hundred annotations based
on data kindly provided by Keith Robison.  The annotations list
probable coding regions within bacterial sequences that are not
annotated as such in GenBank (see Table 2 of K. Robison, W. Gilbert
and G.M. Church, "Large scale bacterial gene discovery by similarity
search", Nature Genetics 7:205, 1994).

We invite the biological community to use the server to view this data
as well as to add data of their own.  Users wishing to view the data
need only the URL listed above and a graphical WWW browser such as
Mosaic or Chimera.  Users wishing to add data would be well-advised to
also prepare the text of their annotation and extended commentary as
well as to have their URL's (if any) in mind before beginning.
Extensive on-line help is provided for both types of users.

Suggestions and comments regarding how the server can best meet the
needs of the biological community are welcome.  There is a comments
form provided in the server for typing in your comments.  Comments may
also be emailed to Randall Smith at rsmith@bcm.tmc.edu.



------------------------------------------------------------------------
Randall F. Smith
Human Genome Center
Department of Molecular and Human Genetics and
W.M. Keck Center for Computational Biology
Baylor College of Medicine
Houston, TX  77030  USA

rsmith@bcm.tmc.edu
713-798-4735; FAX: 713-798-5386
------------------------------------------------------------------------

From owner-embldatabank@net.bio.net Mon Aug 29 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!sun4nl!news.nic.surfnet.nl!news.wau.nl!VLINDERS@rcl.wau.nl
From: vlinders@rcl.wau.nl (Meindert de Jong)
Newsgroups: bionet.molbio.embldatabank
Subject: Invitation for an Academic Promotion
Date: 30 Aug 1994 09:17:56 GMT
Organization: Wageningen Agricultural University
Lines: 20
Message-ID: <33utg4$4j7@trex.iend.wau.nl>
Reply-To: vlinders@rcl.wau.nl
NNTP-Posting-Host: rvd.wau.nl

I just received the PhD Thesis of Dion Florack entitled:
"Application  of Hordothionins and Cecropin B for Engineering
Bacterial Disease Resistance into Plants"
Keywords: biotechnology, genetic engineering, breeding for
bacterial disease resistance;
He will defend his Thesis on September 21 4:00 pm at the
Auditorium of Wageningen Agricultural University.
The promotion will be followed by a reception. A party will be
held in the evening. You are cordially invited to join the
graduation.
Dion's transgenic plants of tobacco and tomato will be exten-
sively tested for field resistance against Xanthomas campes-
tris pv. vesicatoria by the University of Florida.
Dion's business address:
Centre for Plant Breeding and Reproduction Research (CPO-DLO)
P.O.Box 16
6700 AA Wageningen
Netherlands

{Meindert de Jong AKA Vlinders@rcl.wau.NL}

From owner-embldatabank@net.bio.net Tue Aug 30 23:00:00 1994
Newsgroups: bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!library.ucla.edu!agate!dog.ee.lbl.gov!news.cs.utah.edu!emba-news.uvm.edu!brianf
From: brianf@med.uvm.edu (Brian Foley)
Subject: Re: BCM Sequence Annotation Web Server
Message-ID: <1994Aug31.142529.4040@emba.uvm.edu>
Followup-To: bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Sender: news@emba.uvm.edu
Organization: EMBA Computer Facility, University of Vermont
X-Newsreader: TIN [version 1.2 PL1]
References: <RSMITH.94Aug24061420@dot.bcm.tmc.edu>
Date: Wed, 31 Aug 1994 14:25:29 GMT
Lines: 29
Xref: biosci bionet.molbio.genbank:1728 bionet.molbio.embldatabank:360 bionet.molbio.genome-program:921 bionet.molbio.proteins:2562

Randall Smith (rsmith@dot.bcm.tmc.edu) wrote:

:    Announcing a new WWW Server: The BCM Sequence Annotation Server

: URL:  http://dot.imgen.bcm.tmc.edu:9331/seq-annot/home.html

: Developed by Kanwal Gill, Brent Wiese, and Randall Smith
: Human Genome Center, Baylor College of Medicine, Houston TX  USA

: We have created a "Sequence Annotation" WWW Server that allows
: researchers to add their own annotations to Entrez (NCBI) DNA and
: protein sequence reports.  Our Annotation Server is intended as a
: ... deletion to save bandwidth...

	This server appears to require a "forms-based" WWW CLient.
A "forms-based" client has been available for UNIX systems for
a while.  A forms-based client for the Mac was recently released
as well.  It can be obtained from Info-Mac at Sumex-Aim via FTP
it is called Mac-Web and the version there last night was
1.00a.  It works great on my LCIII with only 4Mb or RAM.  The
annotation server above seemed to be down, but I tried it out
on the Genome Database and it worked fine.

--
********************************************************************
*  Brian Foley               *     If we knew what we were doing   *
*  Molecular Genetics Dept.  *     it wouldn't be called research  *
*  University of Vermont     *                                     *
********************************************************************

From owner-embldatabank@net.bio.net Wed Aug 31 23:00:00 1994
Path: biosci!CS.Arizona.EDU!uunet!cs.utexas.edu!howland.reston.ans.net!wupost!bcm!gazette.bcm.tmc.edu!rsmith
From: rsmith@dot.bcm.tmc.edu (Randall Smith)
Newsgroups: bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Subject: Re: BCM Sequence Annotation Web Server
Followup-To: bionet.molbio.genbank,bionet.molbio.embldatabank,bionet.molbio.genome-program,bionet.molbio.proteins
Date: 01 Sep 1994 01:45:29 GMT
Organization: Institute for Molecular Genetics, Baylor College of Medicine
Lines: 46
Distribution: world
Message-ID: <RSMITH.94Aug31204529@dot.bcm.tmc.edu>
References: <RSMITH.94Aug24061420@dot.bcm.tmc.edu> <1994Aug31.142529.4040@emba.uvm.edu>
NNTP-Posting-Host: dot.imgen.bcm.tmc.edu
In-reply-to: brianf@med.uvm.edu's message of Wed, 31 Aug 1994 14:25:29 GMT
Xref: biosci bionet.molbio.genbank:1731 bionet.molbio.embldatabank:361 bionet.molbio.genome-program:923 bionet.molbio.proteins:2572


Brian Foley (brianf@med.uvm.edu's message of Wed, 31 Aug 1994 14:25:29
GMT) wrote:
>Randall Smith (rsmith@dot.bcm.tmc.edu) wrote:
>
>:    Announcing a new WWW Server: The BCM Sequence Annotation Server
>:
>: URL:  http://dot.imgen.bcm.tmc.edu:9331/seq-annot/home.html
>...
>
>	This server appears to require a "forms-based" WWW CLient.
>A "forms-based" client has been available for UNIX systems for
>a while.  A forms-based client for the Mac was recently released
>as well.  It can be obtained from Info-Mac at Sumex-Aim via FTP
>it is called Mac-Web and the version there last night was
>1.00a.  It works great on my LCIII with only 4Mb or RAM.

A forms-based WWW client is needed.  However, Mac Mosaic 2.0a6 *is*
now available from NCSA -- I have it running on my Mac and the forms
work fine.  See:

http://www.ncsa.uiuc.edu/SDG/Software/MacMosaic/MacMosaicHome.html


>The annotation server above seemed to be down, but I tried it out on
>the Genome Database and it worked fine.

Our system disk crashed Mon. afternoon and our machine has been down.
It's up now.  Please try the server out and let us know what you
think.

-Randall Smith


------------------------------------------------------------------------
Randall F. Smith
Human Genome Center
Department of Molecular and Human Genetics and
W.M. Keck Center for Computational Biology
Baylor College of Medicine
Houston, TX  77030  USA

rsmith@bcm.tmc.edu
713-798-4735; FAX: 713-798-5386
------------------------------------------------------------------------


