From owner-embldatabank@net.bio.net Mon Jan 05 22:00:00 1998
Path: biosci!fcs280s.ncifcrf.gov!cpk-news-feed4.bbnplanet.com!cpk-news-feed1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!rill.news.pipex.net!pipex!server1.netnews.ja.net!server5.netnews.ja.net!daresbury!not-for-mail
From: Eugene Kolker <eugene@genome.biotech.washington.edu>
Newsgroups: bionet.molbio.embldatabank
Subject: Recomb98: Registration
Date: 6 Jan 1998 00:09:40 -0000
Lines: 8
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <68rso4$1i1@mserv1.dl.ac.uk>
Original-To: embl-db@dl.ac.uk


                CALL FOR RECOMB 98 Registration

Registration is now starting for RECOMB 98. Please visit our website for
registration instructions:  http://www.mssm.edu/biomath/recomb98.html

If you do NOT want to be in our mailing list, please reply with Subject 
line "Recomb98: remove". 

From owner-embldatabank@net.bio.net Mon Jan 05 22:00:00 1998
Path: biosci!internet!biosci!not-for-mail
From: biohelp (BIOSCI Administrator)
Newsgroups: bionet.molbio.embldatabank
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 6 Jan 1998 02:00:28 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 233
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199801061000.CAA23147@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.


From owner-embldatabank@net.bio.net Wed Jan 07 22:00:00 1998
Path: biosci!agate!logbridge.uoregon.edu!newsfeed.direct.ca!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!stoehr
From: stoehr@ebi.ac.uk (Peter Stoehr)
Newsgroups: bionet.molbio.embldatabank,embnet.general
Subject: EMBL release 53 available
Date: 8 Jan 98 15:41:04 +0000
Organization: European BioInformatics Institute
Lines: 208
Distribution: embnet
Message-ID: <1998Jan8.154104@ebi.ac.uk>
NNTP-Posting-Host: earth.ebi.ac.uk

Release 53 of the EMBL Nucleotide Sequence Database is now available from the
EMBL-EBI ftp site: ftp://ftp.ebi.ac.uk/pub/databases/embl/release

This release is already installed on other EBI query/search servers, 
SRS/Blast/Fasta. A few extracts from the release notes follow, but they can
be read in full at:
 ftp://ftp.ebi.ac.uk/pub/databases/embl/release/relnotes.doc or
 http://www.ebi.ac.uk/ebi_docs/embl_db/relnotes53/relnotes.html

For those who maintain local copies using our cumulative update file in
ftp://ftp.ebi.ac.uk/pub/databases/embl/new/cumulative.dat.Z, please note that
this file will be changed to include only post- release 53 data on Friday
Jan 9th at 15:00 GMT (ie it gets smaller then).

Regards,
Peter Stoehr
EMBL-EBI
--------

1 RELEASE 53

The EMBL Nucleotide Sequence Database was frozen to make Release 53 on the  16th
December  1997.   The  release  contains  1,917,868  sequence entries comprising
1,281,391,651 nucleotides.  This represents an increase of about 8% over Release
52.  A breakdown of Release 53 by division is shown below:

                  Division             Entries     Nucleotides
                  -----------------    -------     -----------
                  Bacteriophage           1388         2188305
                  ESTs                 1343796       496603984
                  Fungi                  18137        44602064
                  GSSs                  100154        49099107
                  HTG                     1868       102763872
                  Human                  74384       139022655
                  Invertebrates          28126       107524431
                  Organelles             24715        22870076
                  Other Mammals          14429        13785092
                  Other Vertebrates      13145        14653255
                  Plants                 22136        37736590
                  Patent                 91221        29511807
                  Prokaryotes            42666       102750354
                  Rodents                37043        46489741
                  STSs                   51172        17685717
                  Synthetic               2424         5377292
                  Unclassified            2380         2387088
                  Viruses                48684        46340221
                  -----------------   --------    ------------
                  Total                1917868      1281391651
                  -----------------   --------    ------------


1.1  EST Database Files

In order to keep the size  of  the  data  files  within  reasonable  limits  for
handling  purposes,  we have split the EST division into several files.  At this
release we have created one extra files of EST data named EST14.DAT.  Additional
files will be added in subsequent releases as appropriate.


1.2  Feature Table Qualifiers

1.2.1  New SOURCE Qualifier /specimen_voucher

This new source feature qualifier valid at this release indicates the source  of
a sample , eg a museum identification tag, of the sequenced material.
Qualifier       /specimen__voucher="text"
Definition      an identifier of the individual or collection of the source
                organism and the place where it is currently stored, usually
                an institution.
Value format    "text"
Example         /specimen__voucher="Smith s. n. 4-IV-1995 (U. S. Natl.
                Herbarium)"


1.2.2  New /focus

This new source feature qualifier valid at this release defines the main  source
feature  for  records with more than one source feature (e.g.  proviral/cellular
sequences)
Qualifier       /focus
Definition      defines the preferred source feature for records that
                have more than one source feature
Value format    none
Example         /focus
Comment         this qualifier is to be used only if there is more than
                one source feature. The preferred source feature is
                used to determine which organism is displayed in
                the SOURCE and ORGANISM lines and to determine the
                EMBL division in which it is placed.

For sequences derived from more than one organism, and therefore containing more
than  one  'source'  feature  key,  the /focus qualifier will be attached to the
source key which represents the major organism, that which was the focus of  the
sequencing  effort.   If  no  translation  table is specified, the organism with
/focus will define the translation table.


2  FORTHCOMING CHANGES

2.1  Nucleotide And Protein Identifiers

2.1.1  Nucleotide Indentifiers

The NI linetype of  the  EMBL  flat-file  format  currently  contains  a  unique
identifier for the nucleotide sequence.  While the sequence remains the same, so
does the value of this identifier.   When  a  sequence  change  occurs,  however
minor,  a  new  NI  value will be assigned whilst the accession number on the AC
line may remain unchanged.  These  identifiers  are  collaboratively  maintained
with GenBank and DDBJ, for example:

     NI   g21954

It has become clear from users and other database groups that confusion has been
created  about  the  relationship between these identifiers and the GenBank 'gi'
numbers.

It  has  been  decided  therefore  to  introduce  a  new  system  of  nucleotide
identifiers  of the form 'accession.version', eg:  X12345.3, where the accession
number part will be stable, but the version part  will  be  incremented  if  the
sequence changes.

Subject to synchronisation of this change with GenBank  and  DDBJ,  we  plan  to
implement this new form of nucleotide identifier during 1998.



2.1.2  Protein Identifiers

Protein identifiers are currently assigned to all CDS features in the nucleotide
sequence database and are found in the feature table qualifier /db_xref, eg:


     /db_xref="PID:e123456789"

As for nucleotide identifier values (above), confusion  resulted  amongst  users
concerning  the  relationship  of these to GenBank 'gi' numbers also assigned to
CDS features.  To clarify this, and to adopt a comparable scheme of  identifiers
for  both  nucleotides and proteins, the collaborating databases have decided to
create a new feature table qualifier /protein_id, eg:

     /protein_id="AAA12345.1"

This form  of  identifier  also  allows  easier  tracking  of  changing  protein
identifiers by external databases than the previous PIDs.


This qualifier consists of a stable ID portion  (3+5  format  with  3  positions
letters and 5 numbers) plus a version number after a decimal point.  The version
number will change only when the protein sequence  coded  by  the  CDS  changes,
while  the stable part will remain unchanged.  This qualifier will be valid only
on CDS features which translate into a valid protein.

Subject to synchronisation of this change with GenBank  and  DDBJ,  we  plan  to
implement this new form of protein identifier during 1998.


2.2  Feature Table Qualifiers

2.2.1  New /protein_id

As mentioned above a new feature table qualifier /protein_id will be created:
Qualifier       /protein_id="<identifier>"
Definition      Protein Identifier, issued by International collaborators.
                This qualifier consists of a stable ID portion (3+5 format
                with 3 positions letters and 5 numbers) plus a version number
                as the decimal point.
Example         /protein_id="AAA12345.1"
Comment         Only when the protein sequence coded by the CDS changes, the
                version number will change, while the stable part will remain
                unchanged. This qualifier is valid only on CDS features which
                translate into a valid protein. The list of 3-letter prefixes
                will be maintained by EBI


Subject to synchronisation of this change with GenBank  and  DDBJ,  we  plan  to
implement this new form of protein identifiers during 1998.


2.2.2  /translation And Related Feature Qualifiers

The collaborating databases  DDBJ/EMBL/GenBank  have  decided  that  translation
related qualifiers should only be used with the primary CDS feature key.

These translation related qualifiers are:

  /codon
  /codon_start
  /exception
  /translation
  /transl_table
  /transl_except


Starting at release 54, translation related qualifiers will only be  valid  with
the  CDS  feature  key  and  will  be removed from the following list of non-CDS
features:

  C_region
  D_segment
  exon
  J_segment
  mat_peptide
  N_region
  sig_peptide
  S_region
  transit_peptide
  V_region
  V_segment

From owner-embldatabank@net.bio.net Wed Jan 14 22:00:00 1998
Path: biosci!agate!ihnp4.ucsd.edu!sdd.hp.com!vixen.cso.uiuc.edu!howland.erols.net!news-peer.gip.net!news.gsl.net!gip.net!peerfeed.ncal.verio.net!Supernews60!supernews.com!uunet!in4.uu.net!news.anet-chi.com!not-for-mail
From: toddc-NoSpAm@NoSpAm-anet-dfw.com (Todd C.)
Newsgroups: bionet.molbio.embldatabank
Subject: PEDANT ?
Date: Thu, 15 Jan 1998 22:22:19 GMT
Organization: ANET Internet Services
Lines: 6
Message-ID: <34be8c0f.106732849@news.anet-dfw.com>
Reply-To: toddc-NoSpAm@NoSpAm-anet-dfw.com
NNTP-Posting-Host: 206.103.93.55
X-Newsreader: Forte Free Agent 1.1/32.230

Does anyome know what happened to PEDANT. Is it no longer publicly
accessable? 

http://pedant.mips.biochem.mpg.de/frishman/pedant.html



From owner-embldatabank@net.bio.net Mon Jan 19 22:00:00 1998
Path: biosci!agate!newsfeed.kornet.nm.kr!nntp.kreonet.re.kr!news.maxwell.syr.edu!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!not-for-mail
From: "Open Windows (John Dawson)" <JLD1@cam.ac.uk>
Newsgroups: bionet.molbio.embldatabank,bionet.molbio.genbank
Subject: Mitochondrial DNA Concordance - new URL
Date: Tue, 20 Jan 1998 12:05:18 +0000
Organization: Open Windows (mail-order book service)
Lines: 10
Message-ID: <34C492F7.7C4C@cam.ac.uk>
Reply-To: Open@ajcox.demon.co.uk
NNTP-Posting-Host: jld.sidg.pwf.cam.ac.uk
Mime-Version: 1.0
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
X-Mailer: Mozilla 3.01 (Macintosh; I; PPC)
CC: kmiller@sscf.ucsb.edu
Xref: biosci bionet.molbio.embldatabank:1061 bionet.molbio.genbank:2865

Please note that the Mitochondrial DNA Concordance
formerly found at  http://alishaw.sscf.ucsb.edu/~kmiller

is now at          http://sscf.ucsb.edu/~kmiller

because of a change of machine names.  We apologise for
any inconvenience.  The Concordance is now being updated; 
the next version should be ready by the end of March 1998.
        John Dawson      JLD1@cam.ac.uk
        Kevin Miller     kmiller@sscf.ucsb.edu

From owner-embldatabank@net.bio.net Mon Jan 26 22:00:00 1998
Path: biosci!daresbury!uninett.no!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!ebi.ac.uk!tome
From: tome@ebi.ac.uk (Patricia Rodriguez-Tome)
Newsgroups: bionet.software,bionet.general,bionet.molbio.embldatabank
Subject: BioCatalog release 5.6
Date: 27 Jan 1998 16:52:13 GMT
Organization: European Bioinformatics Institute (EMBL) - UK
Lines: 21
Distribution: world
Message-ID: <6al3bt$9km$1@niobium.hgmp.mrc.ac.uk>
Reply-To: tome@ebi.ac.uk
NNTP-Posting-Host: sol6.ebi.ac.uk
Xref: biosci bionet.software:20376 bionet.general:29230 bionet.molbio.embldatabank:1064



Release 5.6 of the Biocatalog is out., it contains now 555 entries.
As always the Web server is :
http://www.ebi.ac.uk/biocat

Ascii files are available at : ftp://ftp.ebi.ac.uk/pub/databases/biocat

Submissions are welcome, use the form at :
http://www.ebi.ac.uk/biocat/biocat_form/html

For contact please email biocat@ebi.ac.uk


-- 
=======================================================================
Dr. Patricia Rodriguez-Tome		| URL:  http://www.ebi.ac.uk
The EMBL Outstation, Hinxton - The European Bioinformatics Institute
Wellcome Trust genome Campus, Hinxton	| Tel:	+44 (0)1223 494 409
Cambridge CB10 1SD, UK			| Fax:	+44 (0)1223 494 468
========================================================================

