From owner-embldatabank@net.bio.net Thu Feb 05 22:00:00 1998 Path: biosci!internet!biosci!not-for-mail From: biohelp (BIOSCI Administrator) Newsgroups: bionet.molbio.embldatabank Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 6 Feb 1998 02:00:24 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 233 Sender: daemon@net.bio.net Distribution: world Message-ID: <199802061000.CAA09044@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-embldatabank@net.bio.net Fri Feb 06 22:00:00 1998 Path: biosci!daresbury!not-for-mail From: Eugene Kolker Newsgroups: bionet.molbio.embldatabank Subject: Recomb98: student financial support Date: 7 Feb 1998 00:22:38 -0000 Lines: 34 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <6bg9ge$knj@mserv1.dl.ac.uk> Original-To: embl-db@dl.ac.uk Thanks to the generosity of our governmental and corporate sponsors, limited financial support for travel expenses will be available for students attending RECOMB 98. Support is offered on a competitive basis. In order to apply for financial support, you must: 1) be a graduate student or undergraduate student attending RECOMB 98, 2) register for RECOMB 98 including the submission of registration fees by Feb. 20, 1998, 3) submit a one page essay describing why you should receive financial support. The essay (up to *500* words) should include the following information: i) your name, ii) your email address, iii) the school you are attending, iv) the professor who is overseeing your research, v) a short description of your research, vi) the paper title if you have a paper at RECOMB 98, v) a short description of your research, vi) the paper title if you have a paper at RECOMB 98, vii) the poster title if you have a poster at RECOMB 98, viii) any other information that you think would be relevant. The essay should be sent via email to support@ecology.biomath.mssm.edu by Feb. 20, 1998. Those students selected for financial support will be notified by email on or before March 9, 1998. Early registration ends February 20, 1998! Hotel conference rate ends February 24, 1998! From owner-embldatabank@net.bio.net Sun Feb 08 22:00:00 1998 Path: biosci!daresbury!not-for-mail From: Eugene Kolker Newsgroups: bionet.molbio.embldatabank Subject: Recomb98: Deadlines & Preliminary Program Date: 9 Feb 1998 19:12:20 -0000 Lines: 356 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <6bnkek$nnf@mserv1.dl.ac.uk> Original-To: embl-db@dl.ac.uk Early registration ends February 20, 1998! Hotel conference rate ends February 24, 1998! For more details please visit our web site: http://www.mssm.edu/biomath/recomb98.html ---------------------------------------------------------------------------- RECOMB 98 SCHEDULE Saturday, March 21, 1998 7:00 pm - 10:00 pm Welcome Reception Renaissance Room Sunday, March 22, 1998 8:45 am Opening Remarks Embassy Ballroom Pavel Pevzner, RECOMB 1998 Program Committee Chair Gary Benson, RECOMB 1998 Conference Chair Sorin Istrail, RECOMB 1999 Program Committee Chair 9:00 am Distinguished New Technologies Lecture Pavel Pevzner, Chair David Cox The Human Genetic Variation: Oligonucleotide Chips and Human Disease 10:00 am Break Session 1, Chair: Martin Vingron 10:10 am Identifying Satellites in Nucleic Acid Sequences M. Sagot, G. Meyers 10:35 am Genome Analysis Using Clusters of Orthologous Groups (COGs) E. Koonin, R. Tatusov, M. Y. Galperin, M. N. Rozanov 11:00 am Break Session 2, Chair: Gene Myers 11:15 am Non-Adjoining Correlations Within Signals in DNA P. Agarwal and V. Bafna 11:40 am An Algorithm for Finding Tandem Repeats of Unspecified Pattern Size G. Benson 12:05 pm Lunch 1:30 pm Invited Lecture Session Sorin Istrail, Chair Charles Cantor Enhancements in Sequence Analysis With DNA Arrays 2:30 pm Break Session 3, Chair: Gary Benson 2:40 pm Motif Discovery in Biological Sequences Without Alignment or Enumeration I. Rigoutsos, A. Floratos 3:05 pm An Algorithm for Finding Novel Gapped Motifs in DNA Sequences E. Rocke, M. Tompa 3:30 pm A Polyhedral Approach to RNA Sequence Structure Alignment H. Lenhof, K. Reinert, M. Vingron 3:55 pm Break 4:10 pm Stanislav Ulam Computational Biology Address Michael Waterman, Chair Joshua Lederberg 8:00 pm-10:00 pm Business Meeting Renaissance Room Monday, March 23, 1998 Embassy Ballroom 9:00 am Distinguished Conference Lecture Richard Karp, Chair Ron Davis Whole Genome Analysis: Expression, Replication, Recombination, Allelic Variation, and Drug Discovery Function 10:00 am Break Session 4, Chair: David Searls 10:10 am Assessment of Ab Initio Protein Structure Prediction A. M. Lesk 10:35 am A Self-Consistent Field Optimization Approach to Build Energetically and Geometrically Correct Lattice Models of Proteins B. A. Reva, A. V. Finkelstein, J. Skolnick 11:00 am Break 11:15 am Modeling DNA Shuffling F. Sun 11:40 am Multiple Genome Rearrangements D. Sankoff, M. Blanchette 12:05 pm Lunch 1:30 pm Invited Lecture Session Eugene Koonin, Chair Ruben Abagyan Challenges of biomolecular structure prediction 2:30 pm Break Session 5, Chair: Martin Farach 2:40 pm From Four-taxon Trees to Phylogenies: The Case of Mammalian Evolution A. Ben-Dor, B. Chor, D. Graur, R. Ophir, D. Pelleg 3:05 pm On Reconstructing Species Trees From Gene Trees In Term of Duplications B. Ma, M. Li, L. Zhang 3:30 pm The Ordinal Quartet Method P. E. Kearney 3:55 pm Break 4:10 pm Invited Lecture Session Bonnie Berger, Chair Michael Levitt Bridging the Gap Between Sequence and Structure 6:00 pm-10:00 pm Poster Session Renaissance Room Tuesday, March 24, 1998 Embassy Ballroom 9:00 am Invited Lecture Session Ron Shamir, Chair David Schwartz New Approaches to Genomic Analaysis Using Single Molecules 10:00 am Break Session 6, Chair: Minoru Kanehisa 10:10 am Algorithms for Optical Mapping R. M. Karp, R. Shamir 10:35 am Estimation for Restriction Sites Observed by Optical Mapping Using Reversible-jump Markov Chain Monte Carlo J. K. Lee, V. Dancik, M. S. Waterman 11:00 am Break 11:15 am Partitioning K Clones: Hardness Results and a Practical Solution to the K-Popultaion Problem L. Parida, B. Mishra 11:40 am Constructing Maps Using the Span and Inclusion Relations D. Fasulo, T. Jiang, R. M. Karp, N. Sharma 12:05 pm Lunch 1:30 pm Invited Lecture Session Webb Miller, Chair John Yates Mass spectrometry and the proteome 2:30 pm Break Session 7, Chair: Thomas Lengauer 2:40 pm How Fast a Protein Chain Can Fold to Its Most Stable Structure? A. V. Finkelstein, A. Ya. Badretdinov 3:00 pm Algorithmic Determination of Core Positions in the VL and VH Domains of Immunoglobulin Molecules I. Gelfand, A. Kister, C. Kulikowski, O. Stoyanov 3:30 pm Alignments Without Low-Scoring Regions Z. Zhang, P. Berman, W. Miller 3:55 pm Dynamic Programmimg Alignment Accuracy I. Holmes and R. Durbin 4:20 pm Break 4:30 pm Invited Lecture Session David Haussler, Chair Klaus Gubernator Evolutionary drug discovery Wednesday, March 25, 1998 Embassy Ballroom Session 8, Chair: Dan Gusfield 8:30 am Protein Folding in the Hydrophobic-Hydrophilic (HP) Model is NP-Complete B. Berger, T. Leighton 8:55 am On the Complexity of Protein Folding P. Crescenzi, D. Goldman, C. Papadimitriou, A. Piccolboni, M. Yannakakis 9:20 am A New Method for Modeling and Solving the Protein Fold Recognition Problem Y. Xu, D. Xu, E. C. Uberbacher 9:45 am Optimal Detection of Sequence Similarity by Local Alignment T. Hwa, M. Lassig 10:10 am Break Session 9, Chair: Terry Speed 10:20 am A Formally Exact Method to Numerically Analyze Local Denaturation in Superhelical DNA R. M. Fye, C. J. Benham 10:45 am The Theoretical Limits of DNA Sequence Discrimination of Polyamides W. L. Walker, D. S. Goodsell, E. M. Landaw 11:10 am Maxwell Demon and Topology Simplification by Type II Topoisomerases A. Vologodskii 11:35 am A Unified Approach to Word Statistics M. Regnier 12:00 pm Lunch Session 10, Chair: Phil Green 1:00 pm Regression Analysis of Multiple Protein Structures T. D. Wu, S. C. Schmidler, T. Hastie, D. L. Brutlag 1:25 pm Better Methods for Solving Parsimony and Compatiblity M. Bonet, M. Steel, T. Warnow, S. Yooseph 1:50 pm Beyond Mutation Matrices: Physical-Chemistry Based Evolutionary Models J. M. Koshi, D. P. Mindell, R. A. Goldstein 2:15 pm A Structure Based Similarity Measure for Nucleic Acid Sequence Comparison R. Liu, T. W. Blackwell and D. J. States 2:40 pm Break Session 11, Chair: David Benson 2:55 pm The Hierarchical Organization of Molecular Structure Computations C. C. Chen, J. P. Singh, R. B. Altman 3:20 pm Estimaiton of Allele Frequencies From Color-Multiplexed Electropherograms D. G. Politte, D. R. Maffitt, D. J. States 3:45 pm Analysis of the Position Dependent Amino Acid Probabilities and its Applicationts to the Search for Remote Homologues S. R. Sunyaev, I. V. Rodchenkov, F. Eisenhaber, E. N. Kuznetsov 4:10 pm Family-based Homology Detection via Pairwise Sequence Comparison W. N. Grundy End of RECOMB 98 From owner-embldatabank@net.bio.net Mon Feb 09 22:00:00 1998 Path: biosci!daresbury!uninett.no!Cabal.CESspool!bofh.vszbr.cz!logbridge.uoregon.edu!hammer.uoregon.edu!feeder.is.co.za!news.puk.ac.za!sospc22 From: GABRE@wwg3.uovs.ac.za (Gabre Kemp) Newsgroups: bionet.molbio.embldatabank Subject: PLEASE help: wheat genome size??? Date: Tue, 10 Feb 98 11:04:57 GMT Organization: Univ. of the Orange Free State Lines: 11 Message-ID: <6bpc8p$aog_002@uovs.ac.za> NNTP-Posting-Host: sospc22.uovs.ac.za X-Newsreader: News Xpress Version 1.0 Beta #4 Hi all I urgently need to know the size of the wheat genome (in bp). Please mail me at: gabre@wwg3.uovs.ac.za Thank you Gabre Kemp Department of Botany and Genetics University of the Free State SOUTH AFRICA From owner-embldatabank@net.bio.net Tue Feb 10 22:00:00 1998 Path: biosci!daresbury!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!gin.ebi.ac.uk!sterk From: sterk@gin.ebi.ac.uk (Peter Sterk) Newsgroups: bionet.molbio.embldatabank Subject: Re: PLEASE help: wheat genome size??? Date: 11 Feb 1998 13:01:46 GMT Organization: European Bioinformatics Institute (EMBL) - UK Lines: 22 Distribution: world Message-ID: <6bs7fq$3vc$1@niobium.hgmp.mrc.ac.uk> References: <6bpc8p$aog_002@uovs.ac.za> Reply-To: sterk@gin.ebi.ac.uk (Peter Sterk) NNTP-Posting-Host: gin.ebi.ac.uk X-Newsreader: mxrn 6.18-31 In article <6bpc8p$aog_002@uovs.ac.za>, GABRE@wwg3.uovs.ac.za (Gabre Kemp) writes: >Hi all > >I urgently need to know the size of the wheat genome (in bp). >Please mail me at: gabre@wwg3.uovs.ac.za > > >Thank you >Gabre Kemp Dear Gabre, Plant Molecular Biology, 2nd edition, by Grierson & Covey provides a table listing the nuclear DNA content for a number of plants in picograms. For hexaploid wheat (Triticum aestivum) this is 17.3 pg, which corresponds to 17.3 x 965,000,000 / 6 = 2.800,000,000 base pairs per haploid genome, about the size of the human genome. Peter From owner-embldatabank@net.bio.net Wed Feb 11 22:00:00 1998 Path: biosci!daresbury!not-for-mail From: Eugene Kolker Newsgroups: bionet.molbio.embldatabank Subject: Urgent RECOMB 98 registration deadlines approaching! Date: 12 Feb 1998 23:08:22 -0000 Lines: 7 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <6bvvd6$d8b@mserv1.dl.ac.uk> Original-To: embl-db@dl.ac.uk Early registration ends February 20, 1998! Hotel conference rate ends February 24, 1998! For more details please visit our web site: http://www.mssm.edu/biomath/recomb98.html From owner-embldatabank@net.bio.net Wed Feb 18 22:00:00 1998 Path: biosci!agate!logbridge.uoregon.edu!Cabal.CESspool!bofh.vszbr.cz!lyra.csx.cam.ac.uk!hgmp.mrc.ac.uk!not-for-mail From: Rolf Apweiler Newsgroups: bionet.molbio.embldatabank,bionet.general,embnet.general Subject: Release 5 of TREMBL, a protein sequence database supplementing SWISS-PROT Date: Thu, 19 Feb 1998 16:54:21 +0000 Organization: MRC Human Genome Mapping Project Resource Centre Lines: 94 Distribution: embnet Message-ID: <34EC63BC.EE0F457F@ebi.ac.uk> NNTP-Posting-Host: dhcp4.ebi.ac.uk Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.04 [en] (Win95; I) Xref: biosci bionet.molbio.embldatabank:1078 bionet.general:29387 INTRODUCTION ============ TREMBL is a protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TREMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT. TREMBL can be considered as a preliminary section of SWISS-PROT. For all TREMBL entries which should finally be upgraded to the standard SWISS-PROT quality, SWISS-PROT accession numbers have been assigned. RELEASE 5.0 OF TREMBL ===================== This TREMBL release is created from the EMBL Nucleotide Sequence Database release 53 and contains 166'361 sequence entries, comprising 45'671'684 amino acids. TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL: SP-TREMBL (SWISS-PROT TREMBL) contains the entries (140'555) which should be eventually incorporated into SWISS-PROT. SWISS-PROT accession numbers have been assigned for all SP-TREMBL entries. SP-TREMBL is organized in subsections: fun.dat (Fungi): 4694 entries hum.dat (Human): 6101 entries inv.dat (Invertebrates): 18423 entries mam.dat (Other Mammals): 2444 entries mhc.dat (MHC proteins): 3336 entries org.dat (Organelles): 10561 entries phg.dat (Bacteriophages): 1111 entries pln.dat (Plants): 9871 entries pro.dat (Prokaryotes): 34832 entries rod.dat (Rodents): 5976 entries unc.dat (Unclassified): 109 entries vrl.dat (Viruses): 39943 entries vrt.dat (Other Vertebrates): 3154 entries REM-TREMBL (REMaining TREMBL) contains the entries (25'806) that we do not want to include in SWISS-PROT. WEEKLY UPDATES OF TREMBL AND NON-REDUNDANT DATA SETS ==================================================== Weekly cumulative updates of TREMBL are available by anonymous FTP and from the EBI SRS server. We also produce every week a complete non-redundant protein sequence collection by providing three compressed files (these are in the directory /pub/databases/sp_tr_nrdb on the EBI FTP server): sprot.dat.Z, trembl.dat.Z and trembl_new.dat.Z. ACCESS/DATA DISTRIBUTION ======================== FTP server: ftp.ebi.ac.uk/pub/databases/trembl SRS server: http://srs.ebi.ac.uk:5000/ TREMBL is also available on the SWISS-PROT CD-ROM. SWISS-PROT + TREMBL is searchable on the FASTA3, BLAST2 and Bic_sw servers of the EBI. TREMBL HAS BEEN PREPARED BY: ============================ Rolf Apweiler, Sergio Contrino, Wolfgang Fleischmann, Henning Hermjakob, Vivien Junker, Stephanie Kappus, Fiona Lang, Michele Magrane, Maria Jesus Martin, Steffen Moeller, Nicoletta Mitaritonna and Claire O'Donovan at the EMBL Outstation - European Bioinformatics Institute (EBI) in Hinxton, UK; Amos Bairoch and Alain Gateau at the Medical Biochemistry Department of the University of Geneva, Switzerland. ======================================================================= Rolf Apweiler | SWISS-PROT Coordinator EMBL Outstation | Email:apweiler@ebi.ac.uk European Bioinformatics Institute (EBI) | URL: http://www.ebi.ac.uk Wellcome Trust Genome Campus, Hinxton | Tel: +44 (1223) 494435 Cambridge CB10 1SD, UK | Fax: +44 (1223) 494968 ======================================================================== From owner-embldatabank@net.bio.net Mon Feb 23 22:00:00 1998 Path: biosci!daresbury!not-for-mail From: Eugene Kolker Newsgroups: bionet.molbio.embldatabank Subject: RECOMB 98 Hotel Rooms still available! Date: 24 Feb 1998 20:40:33 -0000 Lines: 13 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <6cvb81$gld@mserv1.dl.ac.uk> Original-To: embl-db@dl.ac.uk RECOMB 98 Hotel Rooms still available! Hotel rooms for RECOMB 98 are almost gone! If you act fast, you can still reserve a hotel room for RECOMB 98 at the convention rate. For reservations call 1-800-231-0405. Mention RECOMB 98 when making your reservation. Hotel conference rate ends TODAY, February 24, 1998! For more details please visit our web site: http://www.mssm.edu/biomath/recomb98.html From owner-embldatabank@net.bio.net Thu Feb 26 22:00:00 1998 Path: biosci!agate!logbridge.uoregon.edu!hammer.uoregon.edu!news.niehs.nih.gov!not-for-mail From: Nick Staffa Newsgroups: bionet.molbio.embldatabank Subject: Bioinformatics Position Date: Fri, 27 Feb 1998 12:44:36 -0500 Organization: NIEHS Lines: 39 Message-ID: <34F6FB83.2C23@niehs.nih.gov> NNTP-Posting-Host: mickeyfinn.niehs.nih.gov Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Mailer: Mozilla 3.01 (Macintosh; I; PPC) Technology Planning and Management Corporation in Research Triangle Park, North Carolina provides computational support to biomedical researchers at the National Institute of Environmental Health Sciences. We are looking for candidates to work in genomic bioinformatics providing cutting edge technological support in the development of two core labs for gene sequencing and expression analysis, and to collaborate with NIEHS scientists. Work on a human genomic polymorphism database and a cDNA database for expression analysis is initially envisioned. Requirements: >> A Ph.D {or equivivalent} in genetics, molecular or cell biology or related field. >> An intermediate to detailed level of understanding of molecular genetics. >> Experience with computational tools for searching genomic, chromosome, and other sequence databases to find and analyse homologies, known genes, motifs, mutations, promoters, regulatory sequences and open reading frames. >> Experience with web-based resources for genomics and sequence analysis. >> Experience with GCG package for sequence analysis. >> Experience in Filemaker Pro or similar relational database desirable. >> Good interpersonal and communication skills a must. >> High level of enthusiasm. Successful candidate will join TPMC’s Science Support Group composed of seven Ph.D. level scientists and computer specialists. Collaboration on short term and long term projects from various NIEHS labs is a possibility as is the proposal and development of your own projects related to science applications and the internet. E-mail or FAXed resumes are welcome. Mail resumes to: Jerry MacNabb Assistant Program Manager Technical Planning and Management Corporation 2222 Chapel Hill - Nelson Highway Durham, NC 27713 Phone: (919) 361-5444 ext. 421 FAX: (919) 361-9680