From owner-embl-db@hgmp.mrc.ac.uk  Tue Feb  1 11:25:11 2000
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From: Sergio <sergioal@solea.quim.ucm.es>
X-Newsgroups: bionet.molbio.embldatabank
Subject: Re: help on bioinformatics
Date: Thu, 27 Jan 2000 01:53:18 +0100
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Check this URL, there are tons of different bioinformatical servers on the net,
but most of them are listed in this one:

http://www.biophys.uni-duesseldorf.de/bionet/rt_1.html

This other one is great to find sequences (proteins or DNA) on the net:

http://srs6.ebi.ac.uk/

And, finally, to aling different sequences or check the homology:

http://www.hgsc.bcm.tmc.edu/SearchLauncher/


hope this help, good luck.


Sergio


Rein wrote:

> Dear Madam/Sir,
>
> We are students of the University of Leuven (Leuven) where we study Applied
> Economical Sciences. We're in the second grade now and some fellow students
> and we were instructed to write a book on bioinformatical software,
> algorithms & applications.
> The problem is that we have problems finding a structure in the
> bioinformatical world due to too much information. Another problem that has
> occured, is that we hardly have any knowledge of biology. We are stuck in a
> labyrinth and therefore I'm posting this to ask wether it would be possible
> if anyone can send us an overview of:
> 1. databases,
> 2. software,
> 3. other usefull information available.
>
> We would be very grateful for any kind of information.
> We thank you in advance and we are looking forward to hearing from you.
>
> Yours sincerely,
>
> Reinout Decock & Catherine Vertriest
> 2nd canditature Applied Economical Sciences,
> University of Leuven, Belgium
> reinout_decock@yahoo.com



From owner-embl-db@hgmp.mrc.ac.uk  Wed Feb  2 05:38:06 2000
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From owner-embl-db@hgmp.mrc.ac.uk  Wed Feb  2 07:51:19 2000
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Subject: Private Offshore Club Pays You by the Minute!
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From owner-embl-db@hgmp.mrc.ac.uk  Fri Feb  4 17:49:10 2000
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http://finance.yahoo.com/q?s=URL.V&d=1d
http://canada.stox.com/
http://www.stox.com/

"The new Stox web site looks interesting and offers a lot of material for
the investor. If this works out it could well be an excellent Canadian
technology story."

"I am surprise that still not too many people use this forum yet. I have
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"Get Ready! Spoke to Dave Perse in investor Relations he said Stox is now
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From owner-embl-db@hgmp.mrc.ac.uk  Fri Feb  4 17:54:24 2000
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From: Richard Friedman <friedman@cuccfa.ccc.columbia.edu>
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Subject: Re: help on bioinformatics
Date: Fri, 04 Feb 2000 12:57:41 -0500
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Dear Reinout & Catherine,

        Being instructre to write a book on a subject you
know nothing about ( as distinct from voluntarily doing
so) sounds horrible. My course notes at:

http://www.ccc.columbia.edu/onlinedocs.html

and

http://www.columbia.edu/itc/hs/medinfo/friedman/g4020/

may help.
Best wishes,
Rich
------------------------------------------------------------
Richard A. Friedman, PhD
Associate Research Scientist
Herbert Irving Comprehensive Cancer Center Computer
and Informatics Resource Center
Lecturer
Department of Medical Informatics
Box 95, Room 130BB or P&S 1-420C
Columbia University
630 W. 168th St.
New York, NY 10032
(212)305-6901 (voice) (212)305-1667 (fax)
friedman@cuccfa.ccc.columbia.edu

"Is ambidextrous mean or good?"
 -Rose Friedman, age 3


From owner-embl-db@hgmp.mrc.ac.uk  Tue Feb  8 00:45:39 2000
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From owner-embl-db@hgmp.mrc.ac.uk  Thu Feb 10 20:30:16 2000
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From owner-embl-db@hgmp.mrc.ac.uk  Thu Feb 10 20:44:27 2000
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From: Peter Stoehr <stoehr@ebi.ac.uk>
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Subject: EMBL cumulative updates
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For those who use the version of the EMBL cumulative update file from the
EBI which has been split into 5 parts, please note that the next incarnation of
this will be in 6 parts, the additional file being cum_htg2.dat.gz

This obviously is the result of a huge increase in the flow of 'high throughput'
genome sequence, especially human, and this change is necessary to prevent
the cum_htg1.dat uncompressed file growing over 2GB

Regards,
Peter Stoehr
EMBL-EBI


From owner-embl-db@hgmp.mrc.ac.uk  Mon Feb 14 01:14:31 2000
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From owner-embl-db@hgmp.mrc.ac.uk  Mon Feb 14 02:32:08 2000
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From: DarlaJones@asiansonly.net
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Subject: Stock  Holders  an  Investors  Dream,  please read
Date: 14 Feb 2000 02:32:04 -0000
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SHAREHOLDER & INVESTOR  ALERT! 
http://216.32.170.10/other/7904568/immce.html

ImmuNis Corp a small Biotech Stock with Big Potential.

The Stock Savvy Investor Forum recommends that you
evaluate the investment potential of ImmuNis Corp shares.

ImmuNis Corp (OTCBB: IMMCE), owns a major interest
in a new class of oral diabetes medication. The drug is referred to as        
DIAB II and has been approved for sale in China and is the final             
stages of the application and registration process in Brazil. 

ImmuNis purchased its 25% interest in the commercial rights
to DIAB II in 1998 for territories outside of Oriental Asia. DIAB II       
is an insulin-receptor sensitizer, a new class of drugs for        
controlling the chronically high blood sugar levels that typify        
adult-onset or Type II diabetes. DIAB II works by improving the        
patient's ability to utilize both endogenous and
injected insulin, the hormone that controls blood sugar levels.

Adult-Onset Diabetes is an illness affecting more than 15
million Americans and more than 150 million people around the world.        
The drug -- DIAB II -- provides excellent control of diabetes symptoms        
without the side-effects of many competing drugs that are already on  the market. 

ImmuNis Corp. has about 8.5 million shares outstanding and
at $1.50 per share price has a market capitalization of under $15        
million in a market segment where the majority of companies trade with        
$100 million valuations in anticipation of a new discovery or               
development. DIAB II confirmed the DIAB II is safe and effective. 

The market for Type II diabetes drugs is over $15 billion
annually. We believe that one should carefully evaluate the potential        
for a much higher stock market valuation of ImmuNis's share price.        
Many analysts are pointing out that companies like ImmuNis with the        
potential of success could produce gains comparable to what has been        
realized in the Dot Com sector.

DIAB II was developed by Biotech Holdings Ltd., a
Canadian-based pharmaceutical company, which controls the 
worldwide manufacturing and marketing rights to the drug. 

In a June 9, 1999 announcement Biotech also pointed out
that there is a sizable and very lucrative market potential for DIAB       
II in Brazil and throughout Latin America -- that for each one percent        
of the diabetic population in Brazil, Argentina and Venezuela using        
DIAB II (a total of 100,000 one-year prescriptions) -- DIAB II sales         
revenues generated would be over $20,000,000 annually. ImmuNis has a        
25% interest in all net revenues from the sale of DIAB II in these        
Latin American Territories as well as in North America and Europe.

In addition to its focus on Latin American markets where
license agreements have been completed in Brazil with Biobras, which        
is the fourth largest insulin manufacturer in the world with 75% of       
the diabetes medication market in Brazil. Agreements have also been          
completed in Argentina, Venezuela, Peru and Chile.

An agreement with a major (more than $10 billion in sales)
pharmaceutical company was announced in September of 1999, that
foresees potential licensing of DIAB II, for the U.S. market. Biotech        
expects to be working closely with this prospective licensing partner       
to review data and arrange for testing of DIAB II. The goal is to        
reach a licensing agreement that would provide for testing of DIAB II        
and filing of an application with the U.S. FDA, with the possibility        
that other markets could also be included in a final agreement.

Biotech Holdings completed the first phase of its drug
production facility Canadian Health Pr otection 
Branch, that certifies that Biotech has met GMP (Good
Manufacturi in Richmond, B.C. This notice of approval brings DIAB II        
to the final stages of entering the market in Brazil and throughout        
Latin American. Registration dossiers for the sale of DIAB II are now        
planned for submission in Chile, Argentina, Venezuela and Peru.        
Registration filings are also expected in the Middle East, Southern        
Europe and Africa.

The DIAB II Brazilian clinical trials provided supplementary
information for the regulatory application for approval of DIAB II, in        
Brazil as a prescription treatment for Type II or Adult-Onset        
Diabetes. The trial was carried out by one of the largest independent        
contract research laboratories in Brazil, working with Brazilian             
doctors specializing in diabetes. The trials showed that during DIAB        
II treatment that no adverse clinical events were reported. Plasma       
insulin, HDL/LDL ratio and triglycerides were controlled equally well        
with DIAB II treatment as on the patients' accustomed medication. The        
critical Hb A1c measurement showed
reduced levels during the course of the study, to an average of 5.85%,        
(well within normal ranges) indicating excellent diabetic control

The shares of ImmuNis represent a opportunity for very
substantial gains.  However, the shares must be regarded as        
speculative. Even though the indications are that the drug will        
continue to prove to be safe and effective, obtaining final approval        
for sale and distribution in Western Countries may take time or may        
not occur at all. We always recommend that one investigate and        
evaluate the potential and risks of any investment. 

       Visit the company's website at
      http://216.32.170.10/other/7904568/immce.html

         or send us an E-mail at   ebi@katchup.co.nz
       or call 1-714-877-2785 for more info today.
       : : : : : : : : : : : : : : : : : : : : : : : : : : :
Nothing in this e-mail shou ld be construed as a solicitation.
Please consult an investment professional.
This is an alert and is for INFORMATIONAL purposes only.

       - - - - - - - - - - - - - - - - - - - - - - - - - - - -
The Stock Savvy Investor takes pride in our careful efforts
to reach people who are truly interested in what we have to offer. 

You have received this message via a news service subscription or an       
affiliation of such. 

       
If in error, please delete hit button to hear no more.
       
---


From owner-embl-db@hgmp.mrc.ac.uk  Mon Feb 14 15:27:54 2000
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From: Peter Sterk <sterk@ebi.ac.uk>
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Subject: Campylobacter jejuni genome available from EBI genome web server
Date: Mon, 14 Feb 2000 15:27:45 +0000
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The complete Campylobacter jejuni NCTC 11168 genome sequence, 
sequenced by the Sanger Centre and published in Nature 403, 
665-668 (2000), is available from the EBI Genome Web Server, URL
http://www3.ebi.ac.uk/Services/genomes/ and through SRS, URL
http://srs6.ebi.ac.uk/ . The complete sequence is 1,641,481 bp in length
and can be accessed under accession number AL111168.


==========================================================================
Dr. Peter Sterk                                     Email: sterk@ebi.ac.uk
Genome Project Curator                              Tel  : +44 1223 494464
EMBL Nucleotide Sequence Database                   Fax  : +44 1223 494468

EMBL Outstation Hinxton, The European Bioinformatics Institute,
Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, U.K.
WWW homepage: http://www.ebi.ac.uk
==========================================================================


From owner-embl-db@hgmp.mrc.ac.uk  Mon Feb 14 16:47:49 2000
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From: "Faramarz Valafar" <faramarz@cns.bu.edu>
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Subject: METMBS'2000 Call for PApers
Date: Mon, 14 Feb 2000 11:49:55 -0500
Organization: Boston University
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The 2000 International Conference on Mathematics and Engineering
Techniques in Medicine and Biological Sciences
(METMBS'2000)
<http://www.cns.bu.edu/metmbs/>

June 26 - 29, 2000
Monte Carlo Resort, Las Vegas, Nevada, USA
Call for Papers



Recent advances in computer technology have provided the tools and the
environment to study, analyze, and better understand complex systems. This
technological development has enabled researchers to collect and analyze
massive amounts of data to a scale previously not possible. The impact of
this technology is now being felt in the medical field and in the biological
sciences.   In recent years, research in interdisciplinary areas such as
Bioinformatics and computer assisted medical decision-making has
dramatically intensified.  METMBS'2000 aims to provide a platform for
researchers to present and discuss recent breakthroughs in this area.

The METMBS'2000 Conference will be held concurrently (i.e., same location
and dates) with the International Conference on Parallel and Distributed
Processing Techniques and Applications (PDPTA'2000), the International
Conference on Imaging Science, Systems, and Technology (CISST) and the
International Conference on Artificial Intelligence (IC-AI).

You are invited to submit a draft paper of about 4 pages and/or a proposal
to organize a technical session (see below for submission information).  All
accepted papers will be published in the conference proceedings.

THE NAMES OF TECHNICAL SESSION CHAIRS WILL APPEAR AS ASSOCIATE EDITORS ON
THE COVER OF THE CONFERENCE PROCEEDINGS.



SCOPE

Topics of interest include, but are not limited to, the following:

o Bioinformatics: This includes informatics techniques in genomics gene
sequencing, gene pattern discovery, gene pattern-function studies, and other
genomics related studies).

o Data mining in medicine and biological sciences.

o Pattern recognition in medicine and biological sciences.

o Signal processing in medicine and biological sciences (e.g. biomedical
signal processing, etc.)
o Image processing in medicine and biological sciences (e.g. biomedical
image processing, biomedical imaging, etc.)

o Medical decision-making.
o Medical Physics.
o Biomedical Engineering.
o Biomedical Electronics.
o Biosignal interpretation.
o Any application of computers in Medicine and biological sciences (protein
structure-function analysis, drug and protein design, molecular modeling and
simulation, etc.)
o Application of information technology in biomedicine (e.g. medical
database management, information retrieval and use of computers in
hospitals)
o Application of Computational Intelligence (artificial neural networks,
fuzzy logic, and evolutionary computing) in medicine and biological sciences
o Medical and bio-computing.
o Computer-based medical systems (automation in medicine, etc.)
o Recent history (1990-1999) of Mathematics and engineering techniques in
medicine and biological sciences, and what to expect during the next decade
(2000-2009); New horizons. Review articles)
o Other aspects and applications relating to technological advancements in
medicine and biological sciences.



SUBMISSION OF PAPERS

Prospective authors are invited to submit three copies of their draft paper
(about 4 pages) to F. Valafar (address is given below) by February 28, 2000.
E-mail and Fax submissions are also acceptable.  The length of the
Camera-Ready papers (if accepted) will be limited to 7 pages.  Papers must
not have been previously published or currently submitted for publication
elsewhere.

The first page of the draft paper should include: title of the paper, name,
affiliation, postal address, E-mail address, telephone number, and Fax
number for each author.  The first page should also include the name of the
author who will be presenting the paper (if accepted) and a maximum of 5
keywords.


PROPOSAL FOR ORGANIZING TECHNICAL SESSIONS

Each technical session will have  at least 6 paper presentations.  The
session chairs will be responsible for all aspects of their sessions,
including soliciting papers, reviewing, selecting, ...

The names of session chairs will appear as Associate Editors in the
conference proceedings.  After the conference, some sessions will be
considered for publication in appropriate journals as Special Issues with
the session proposer as the Guest Editor of the journal.

Proposals to organize technical sessions should include the following
information: name and address (+ E-mail) of the proposer, title of session,
a 100-word description of the topic of the session, and a short description
on how the session will be advertised (in most cases, session proposers
solicit papers from colleagues and researchers whose work is known to the
session proposer).

Mail your proposal to F. Valafar (address is given below); E-mail
submissions are preferred.


EVALUATION PROCESS

Papers will be evaluated for originality, significance, clarity, and
soundness.  Two researchers in the topical area will referee each paper.
The Camera-Ready papers will be reviewed by one person.


PUBLICATION

The conference proceedings will be published by CSREA Press (ISBN).  The
proceedings will be available at the conference.  Some accepted papers will
also be considered for journal publication (soon after the conference).


ORGANIZERS/SPONSORS

A number of university faculty members and their staff, in cooperation with
the Monte Carlo Resort (Conference Division, Las Vegas), will be organizing
the conference.  The conference will be sponsored by Computer Science
Research, Education, & Applications Press (CSREA: USA Federal EIN #
58-2171953) in cooperation with research centers, international
associations, international research groups, and developers of
high-performance machines and systems.  The complete list of sponsors and
co-sponsors will be available at a later time.

The last conference's sponsors included: CSREA, the National Supercomputing
Center for Energy and the Environment - DOE, The International Association
for Mathematics and Computers in Simulation, The International Technology
Institute (ITI), The Java High Performance Computing research group, Korea
Information Processing Society, World Scientific and Engineering Society,
Sundance Digital Signal Processing Inc., the Computer Vision Research and
Applications Tech., and more.


LOCATION OF CONFERENCE

The conference will be held in the Monte Carlo Resort Hotel, Las Vegas,
Nevada, USA.  This is a mega hotel with excellent conference facilities and
over 3000 rooms.  The hotel is minutes from the Las Vegas airport with free
shuttles to and from the airport.  This hotel has many vacation and
recreational attractions, including: waterfalls, casino, spa, pools & kiddie
pools, sunning decks, Easy River water ride, wave pool with cascades,
lighted tennis courts, health spa (with workout equipment, whirlpool, sauna,
...), arcade virtual reality game rooms, nightly shows, snack bars, a number
of restaurants, shopping area, bars, ...  Many of these attractions are open
24 hours a day and most are suitable for families and children.  The
negotiated hotel's room rate for conference attendees is very reasonable
($79 + tax) per night (no extra charge for double occupancy) for the
duration of the conference.

The hotel is within walking distance from most other Las Vegas attractions
(major shopping areas, recreational destinations, fine dining and night
clubs, free street shows, and more).

For the benefit of our international colleagues: the state of Nevada
neighbors with the states of California, Oregon, Idaho, Utah, and Arizona.
Las Vegas is only a few driving hours away from other major cities and
attractions, including: Los Angeles, San Diego, Phoenix, the Grand Canyon,
and more.


EXHIBITION

An exhibit is planned for the duration of the conference.  We have reserved
20+ exhibit spaces.  Interested parties should contact F. Valafar (address
is given below).  All exhibitors will be considered to be the co-sponsors of
the conference.


IMPORTANT DATES

February 28, 2000 (Monday): Draft papers (about 4 pages) due
April 3, 2000 (Monday):  Notification of acceptance
May 1, 2000 (Monday):  Camera-Ready papers & Prereg. due
June 26 - 29, 2000:  PDPTA'2000 Conference

Proposals to organize technical sessions should be submitted as soon as
possible.  All accepted papers are expected to be presented at the
conference.


MEMBERS OF PROGRAM & ORGANIZING COMMITTEES

The Program Committee is currently being formed.  Those interested in
joining the Program Committee should e-mail F. Valafar (faramarz@cns.bu.edu
<mailto:faramarz@cns.bu.edu>) the following information: Name, affiliation
and position, complete mailing address, e-mail address, tel/fax numbers, a
short biography together with research interests.


OTHER INFORMATION

Last year PDPTA, CISST, and IC-AI had research contributions from over 44
countries (over 900 participants from all over the world.)  To make this a
more complete suite of conferences, we have added METMBS.  METMBS will also
have a strong international flavor and offers its participants an
introduction to a wide range of related interdisciplinary subjects through
the other three conferences.


CONFERENCE CONTACT:

          Faramarz Valafar
          Cognitive and Neural Systems
          Boston University
          677 Beacon Street
          Boston, MA 02215

          Tel: (617) 353-5134
          Fax: (617) 353-7755
          E-mail: Faramarz@cns.bu.edu <mailto:Faramarz@cns.bu.edu>

















---









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From owner-embl-db@hgmp.mrc.ac.uk  Fri Feb 18 17:12:06 2000
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From: rls@ebi.ac.uk (Rodrigo Lopez)
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Subject: server changes at the EBI
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From owner-embl-db@hgmp.mrc.ac.uk  Sat Feb 19 03:24:28 2000
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From owner-embl-db@hgmp.mrc.ac.uk  Mon Feb 28 11:32:49 2000
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 This newgroup message changes bionet.molbio.embldatabank to moderated
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