From owner-gdb@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!darwin.sura.net!news.gdb.org!freya.gdb.org!patty
From: patty@gdb.org (Patty Haley)
Newsgroups: bionet.molbio.gdb
Subject: GDB Services on Monday, Nov. 8th
Message-ID: <1993Nov1.144727.13337@news.gdb.org>
Date: 1 Nov 93 14:47:27 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Organization: Genome Database
Lines: 17
Nntp-Posting-Host: freya.gdb.org



        Some GDB Services Unavailable Monday November 8 from 7-11am EST
==============================================================================
 
Due to computer maintenance, the following GDB services will be unavailable 
on Monday November 8, 1993 from 7-11am EST (Eastern Standard Time) from
Johns Hopkins University in Baltimore, MD.
 
        . FTP server (ftp.gdb.org)
        . GDB/Accessor
        . Public ISQL
 
We apologize for any inconvenience this may cause.
 
Please note that access to the GDB application via telnet to Johns Hopkins 
University (gdb.gdb.org) WILL BE AVAILABLE as usual during this time.

From owner-gdb@net.bio.net Mon Nov 01 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!darwin.sura.net!news.gdb.org!freya.gdb.org!patty
From: patty@gdb.org (Patty Haley)
Newsgroups: bionet.molbio.gdb
Subject: Services on November 8th
Message-ID: <1993Nov1.185803.15110@news.gdb.org>
Date: 1 Nov 93 18:58:03 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Organization: Genome Database
Lines: 17
Nntp-Posting-Host: freya.gdb.org



        Some GDB Services Unavailable Monday November 8 from 7-11am EST
==============================================================================
 
Due to computer maintenance, the following GDB services will be unavailable 
on Monday November 8, 1993 from 7-11am EST (Eastern Standard Time) from
Johns Hopkins University in Baltimore, MD.
 
        . FTP server (ftp.gdb.org)
        . GDB/Accessor
        . Public ISQL
 
We apologize for any inconvenience this may cause.
 
Please note that access to the GDB application via telnet to Johns Hopkins 
University (gdb.gdb.org) WILL BE AVAILABLE as usual during this time.

From owner-gdb@net.bio.net Tue Nov 02 22:00:00 1993
Path: biosci!CHPC.UTEXAS.EDU!mwitten
From: mwitten@CHPC.UTEXAS.EDU
Newsgroups: bionet.molbio.gdb
Subject: URGENT: DEADLINE CHANGE FOR WORLD CONGRESS
Message-ID: <9311031731.AA07956@morpheus.chpc.utexas.edu>
Date: 3 Nov 93 17:31:16 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 68


		   UPDATE ON DEADLINES
FIRST WORLD CONGRESS ON COMPUTATIONAL MEDICINE, PUBLIC
	     HEALTH, AND BIOTECHNOLOGY
		    24-28 April 1994
                   Hyatt Regency Hotel
                     Austin, Texas
----- (Feel Free To Cross Post This Announcement) ----

Due to a confusion in the electronic distribution of
the congress announcement and deadlines, as well as 
incorrect deadlines appearing in a number of society
newsletters and journals, we are extending the abstract
submission deadline for this congress to 31 December 1993.
We apologize to those who were confused over the differing
deadline announcements and hope that this change will
allow everyone to participate. For congress details:

To contact the congress organizers for any reason use any of the
following pathways:

ELECTRONIC MAIL - compmed94@chpc.utexas.edu

FAX (USA)       - (512) 471-2445

PHONE (USA)     - (512) 471-2472

GOPHER: log into the University of Texas System-CHPC
select the Computational Medicine and Allied Health
menu choice

ANONYMOUS FTP: ftp.chpc.utexas.edu
	     cd /pub/compmed94
	(all documents and forms are stored here)

POSTAL:
            Compmed 1994
      University of Texas System CHPC
            Balcones Research Center
            10100 Burnet Road, 1.154CMS
            Austin, Texas 78758-4497

SUBMISSION PROCEDURES: Authors must submit 5
copies of a single-page 50-100 word abstract clearly
discussing the topic of their presentation. In
addition, authors must clearly state their choice of
poster, contributed paper, tutorial, exhibit, focused
workshop or birds of a feather group along with a
discussion of their presentation. Abstracts will be
published as part of the preliminary conference
material. To notify the congress organizing committee
that you would like to participate and to be put on
the congress mailing list, please fill out and return
the form that follows this announcement.  You may use
any of the contact methods above. If you wish to
organize a contributed paper session, tutorial
session, focused workshop, or birds of a feather
group, please contact the conference director at
mwitten@chpc.utexas.edu . The abstract may be submitted
electronically to  compmed94@chpc.utexas.edu  or
by mail or fax. There is no official format.


If you need further details, please contact me.

Matthew Witten
Congress Chair
mwitten@chpc.utexas.edu

From owner-gdb@net.bio.net Tue Nov 09 22:00:00 1993
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!news.gdb.org!org.gdb!help
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: GDB Release 5.2 Coming November 29 Features Enhanced Output
Message-ID: <1993Nov10.182902.13906@news.gdb.org>
Date: 10 Nov 93 18:29:02 GMT
Sender: news@news.gdb.org
Reply-To: bionet.molbio.gdb
Organization: Johns Hopkins University Genome Data Base (GDB)
Lines: 28
Nntp-Posting-Host: velociraptor.gdb.org

GDB Release 5.2 Coming November 29 Features Enhanced Output
-----------------------------------------------------------

The new GDB release is scheduled to be installed on the computer at Johns
Hopkins University in Baltimore on Monday November 29. Access to GDB and to
the Public ISQL server at JHU will be unavailable on this day while the 
database is converted.

This release of the software will feature revised output report generation 
and includes an Output Manager with the look-and-feel of the data managers as
well as several new output features requested by the user community.

Due to the change in how output is handled, any User Defined reports saved in
GDB 5.1 will be lost when the conversion to 5.2 occurs. Users will need to 
define and save these reports again. We apologize for the inconvenience and
will be glad to provide assistance in redefining reports for 5.2.

When the new GDB software has been installed, we will post a detailed 
description of how to use the Output Manager as well as other enhancements 
included in this release.

People with GDB/Accessor installed on their Macs will be able to update
their software automatically. We will post a description of how to do this
as soon as the new version of the GDB/Accessor software is available.

For information about accessing GDB, please contact:
        GDB User Support
        help@gdb.org

From owner-gdb@net.bio.net Wed Nov 10 22:00:00 1993
Path: biosci!daresbury!bioftp.unibas.ch!embl-heidelberg.de!rice
From: rice@embl-heidelberg.de (Peter Rice)
Newsgroups: bionet.molbio.gdb
Subject: Re: GDB Release 5.2 Coming November 29 Features Enhanced Output
Message-ID: <1993Nov11.173546.127366@embl-heidelberg.de>
Date: 11 Nov 93 16:35:46 GMT
References: <1993Nov10.182902.13906@news.gdb.org>
Organization: EMBL, European Molecular Biology Laboratory
Lines: 17

In article <1993Nov10.182902.13906@news.gdb.org>, help@gdb.org writes:
> GDB Release 5.2 Coming November 29 Features Enhanced Output
>
> People with GDB/Accessor installed on their Macs will be able to update
> their software automatically. We will post a description of how to do this
> as soon as the new version of the GDB/Accessor software is available.

I saw a nice demo of GDB/Accessor on the Mac recently, but when will an
MS-Windows or an X-Windows version appear?

 -----------------------------------------------------------------------------
 Peter Rice, EMBL                             | Post: Computer Group
                                              |       European Molecular
 Internet:    Peter.Rice@EMBL-Heidelberg.DE   |            Biology Laboratory
                                              |       Postfach 10-2209
 Phone:   +49-6221-387247                     |       69012 Heidelberg
 Fax:     +49-6221-387306                     |       Germany

From owner-gdb@net.bio.net Thu Nov 11 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!pipex!sunic!trane.uninett.no!nntp.uio.no!NewsWatcher!user
From: olam@radium.uio.no (Ola Myklebost)
Newsgroups: bionet.molbio.gdb
Subject: GDB/Accessor in Sweden
Message-ID: <olam-121193110448@129.240.38.55>
Date: 12 Nov 93 10:04:48 GMT
Followup-To: bionet.molbio.gdb
Organization: Inst for Cancer Research, Oslo
Lines: 19
NNTP-Posting-Host: pcdnr05.uio.no
Mime-Version: 1.0
Content-Type: text/plain; charset=ISO-8859-1
Content-Transfer-Encoding: 8bit

I have just received a version of GDB/Accessor 1.0b which is set up to work
on the Swedish GDB node. This works very well in this part of the world and
can be highly recommended.

I assume the program can be obtained from through help@gdb.embnet.se,
although I never got any response directly from them (I got the program
from our local embnet administrator after his visit there).

Thanks to everyone who has helped me on the way!

Ola

-- 
Ola Myklebost             Email  ola.myklebost@dnr.uio.no
Dept of Tumor Biology
Inst for Cancer Research
The Norwegian Radium Hospital
N-0310 OSLO, Norway
Tel +47-22-50-60-50, xtn 9830, Fax +47-22-52-24-21

From owner-gdb@net.bio.net Mon Nov 15 22:00:00 1993
Path: biosci!lhc!darwin.sura.net!paladin.american.edu!europa.eng.gtefsd.com!uunet!EU.net!hp4at!news.univie.ac.at!swidir.switch.ch!news.unige.ch!medsun.unige.ch!mike
From: mike@medsun.unige.ch (Mike Morris)
Newsgroups: bionet.molbio.gdb
Subject: Re: GDB Release 5.2 Coming November 29 Features Enhanced Output
Message-ID: <1993Nov15.162412.22180@news.unige.ch>
Date: 15 Nov 93 16:24:12 GMT
References: <1993Nov10.182902.13906@news.gdb.org> <1993Nov11.173546.127366@embl-heidelberg.de>
Sender: usenet@news.unige.ch
Organization: University of Geneva, Switzerland
Lines: 13


  I too vote for an X-Windows version! 

  Who else?


*******************************************************************
Mike Morris PhD               * *
Division of Medical Genetics  * *  tel (Switzerland) (22) 702.56.94
University of Geneva          * *  fax (Switzerland) (22) 702.57.06
Geneva                        * *        email mike@medsun.unige.ch
Switzerland                   * *
*******************************************************************

From owner-gdb@net.bio.net Fri Nov 19 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!agate!howland.reston.ans.net!darwin.sura.net!news.gdb.org!org.gdb@help
From: help@gdb.org (GDB User Support)
Newsgroups: bionet.molbio.gdb
Subject: New Genethon Data Entered Into GDB
Message-ID: <1993Nov18.210551.16240@news.gdb.org>
Date: 18 Nov 93 21:05:51 GMT
Sender: news@news.gdb.org
Reply-To: bionet.molbio.gdb
Organization: Johns Hopkins University Genome Data Base (GDB)
Lines: 24
Nntp-Posting-Host: velociraptor.gdb.org

New Genethon Data Entered Into GDB
==================================
 
        The PCR and microsatellite data from the latest set of highly-
informative markers from Genethon have been loaded into GDB. This set
consists of over 1200 new clone, PCR, polymorphism and locus records, complete 
with PCR conditions and allele frequency information.
 
        The easiest way to access this data in GDB is to first retrieve the
GDB ID # G00-230-332, then call the Locus, Probe or Polymorphism Managers
to retrieve the Genethon data.


======================================================================

David Kitaguchi, Sr. User System Specialist  WHOIS - DGK2
GDB/OMIM User Support                            Phone: (410) 955-9664
Johns Hopkins University School of Medicine      FAX:   (410) 614-0434 
2024 E. Monument Street
Baltimore, MD  21205-2100                          
help@gdb.org 
davidk@gdb.org

======================================================================

From owner-gdb@net.bio.net Fri Nov 19 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!agate!library.ucla.edu!europa.eng.gtefsd.com!darwin.sura.net!news.gdb.org!oscar.gdb.org!ken
From: ken@oscar.gdb.org (Ken Fasman)
Newsgroups: bionet.molbio.gdb
Subject: Re: GDB Release 5.2 Coming November 29 Features Enhanced Output
Summary: we're working on it
Keywords: GDB Macintosh Windows
Message-ID: <1993Nov20.221508.16358@news.gdb.org>
Date: 20 Nov 93 22:15:08 GMT
References: <1993Nov10.182902.13906@news.gdb.org> <1993Nov11.173546.127366@embl-heidelberg.de>
Sender: Ken Fasman
Followup-To: bionet.molbio.gdb
Organization: Genome Data Base, Johns Hopkins University
Lines: 39
Nntp-Posting-Host: oscar.gdb.org

In article <1993Nov11.173546.127366@embl-heidelberg.de> rice@embl-heidelberg.de (Peter Rice) writes:
>
>I saw a nice demo of GDB/Accessor on the Mac recently, but when will an
>MS-Windows or an X-Windows version appear?

GDB/Accessor was written at Cold Spring Harbor by Corp Reed and Tom Marr, 
using MPW C, a development system native to the Macintosh.  Because of this, 
it cannot be easily ported to other systems.

We will shortly release an experimental SmallTalk-based GUI browser for GDB 
which will run on Macs, MS Windows, and Unix systems using ParcPlace's 
SmallTalk 80 run time system.  Watch this newsgroup or the Human Genome News 
newsletter for more details about this software, including how to get the 
necessary run-time license for SmallTalk.

We are also working with another group on implementing a program comparable 
to GDB/Accessor under MS-Windows, possibly using MS Access as the development 
system.  We are shooting for delivery by the end of 1994 (possibly sooner) 
for this program.

For further information, please contact GDB User Support at:

help@gdb.org

(410) 955-7058 (voice)
(410) 614-0434 (fax)

2024 E. Monument St.
Baltimore MD  21205


Ken Fasman
Informatics Director
Genome Data Base
Johns Hopkins University School of Medicine
2024 E. Monument St.
Baltimore MD  21205

ken@gdb.org

From owner-gdb@net.bio.net Tue Nov 23 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!uunet!news.moneng.mei.com!howland.reston.ans.net!darwin.sura.net!news.gdb.org!org.gdb!help
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: Internet access to GDB unavailable for short time on Friday Nov. 26
Message-ID: <1993Nov23.220137.29685@news.gdb.org>
Date: 23 Nov 93 22:01:37 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Followup-To: bionet.molbioo.gdb
Organization: Johns Hopkins University Genome Data Base (GDB)
Lines: 7
Nntp-Posting-Host: velociraptor.gdb.org


Internet access to GDB unavailable for short time on Friday Nov. 26
===================================================================

On Friday November 26, 1993 the SURAnet router which provides Internet
access to GDB will be down for maintenance between 4am-5am Eastern Time.
Total downtime once maintenance is started should not exceed 15 minutes.

From owner-gdb@net.bio.net Tue Nov 23 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!uknet!pipex!howland.reston.ans.net!paladin.american.edu!darwin.sura.net!news.gdb.org!org.gdb!help
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: GDB Release 5.2 Coming November 29 Features Enhanced Output
Message-ID: <1993Nov23.220900.29830@news.gdb.org>
Date: 23 Nov 93 22:09:00 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Followup-To: bionet.molbio.gdb
Organization: Johns Hopkins University Genome Data Base (GDB)
Lines: 29
Nntp-Posting-Host: velociraptor.gdb.org


GDB Release 5.2 Coming November 29 Features Enhanced Output
-----------------------------------------------------------

The new GDB release is scheduled to be installed on the computer at Johns
Hopkins University in Baltimore on Monday November 29. Access to GDB and to
the Public ISQL server at JHU will be unavailable on this day while the 
database is converted.

This release of the software will feature revised output report generation 
and includes an Output Manager with the look-and-feel of the data managers as
well as several new output features requested by the user community.

Due to the change in how output is handled, any User Defined reports saved in
GDB 5.1 will be lost when the conversion to 5.2 occurs. Users will need to 
define and save these reports again. We apologize for the inconvenience and
will be glad to provide assistance in redefining reports for 5.2.

When the new GDB software has been installed, we will post a detailed 
description of how to use the Output Manager as well as other enhancements 
included in this release.

People with GDB/Accessor installed on their Macs will be able to update
their software automatically. We will post a description of how to do this
as soon as the new version of the GDB/Accessor software is available.

For information about accessing GDB, please contact:
        GDB User Support
        help@gdb.org

From owner-gdb@net.bio.net Mon Nov 29 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!warwick!pipex!howland.reston.ans.net!darwin.sura.net!news.gdb.org!org.gdb!hgelp
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: New GDB 5.2 Temporarily 0ff-line
Message-ID: <1993Nov30.184110.25375@news.gdb.org>
Date: 30 Nov 93 18:41:10 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Followup-To: bionet.molbio.gdb
Organization: The Johns Hopkins University - Genome Data Base (GDB)
Lines: 24
Nntp-Posting-Host: velociraptor.gdb.org

*******************************************************************************
*                                                                             *
*                     New GDB 5.2 Temporarily 0ff-line                        *
*                                                                             *
*******************************************************************************


        GDB Version 5.2 was due to be installed and loaded by 8:00am 

        this morning.  


        As we are in the process of completing the load of GDB data 

        into the new software, the database has been taken 

        off-line until late this afternoon (30 November 93).


        We will post an additional message once the database is fully 
        
        loaded and on-line for use.  Any questions or comments, please

	contact us at help@gdb.org

From owner-gdb@net.bio.net Mon Nov 29 22:00:00 1993
Path: biosci!mrc-crc.ac.uk
From: smercer@mrc-crc.ac.uk (Mr. S.J. Mercer)
Newsgroups: bionet.announce,bionet.genome.chromosomes,bionet.molbio.gdb
Subject: Chromosome Database available on Gopher
Keywords: Chromosome Database Gopher
Message-ID: <1993Nov30.145230.28881@crc.ac.uk>
Date: 30 Nov 93 14:52:30 GMT
Sender: kristoff@net.bio.net
Followup-To: poster
Organization: MRC Human Genome Resource Centre
Lines: 31
Approved: bionews-moderator@net.bio.net
Xref: biosci bionet.announce:814 bionet.genome.chromosomes:115 bionet.molbio.gdb:135


                              ANNOUNCEMENT

The Chromosome Abnormality Database is now available by Gopher from the
UK Human Genome Mapping Project Resource Centre (HGMP-RC).

This database was established early in 1991,to collect records of chromsosome 
abnormalities (of all types) from the fifty or so laboratories in the United 
Kingdom which perform routine diagnostic karyotyping. Ordinarily, the records 
of abnormal samples were held separately by each laboratory, but the Chromosome
Abnormality Database (CAD) acts as a centralised repository for this 
information and enabling researchers to locate samples of interest without 
having to contact all of the laboratories individually.

The CAD now stores over forty thousand records of chromosome abnormality
and for each record holds the sex, date of birth, tissue type and karyotype,
as well as details of the lab from which the record was collected. It also
holds information on the availability of stored samples and cell lines where
these are available.

Point your gopher at menu.hgmp.mrc.ac.uk port 70 or make a link:

Name: Chromosome Abnormality Database
Type: 1
Port: 70
Path: 1/HGMP_DBs/Cad_DB
Host: menu.hgmp.mrc.ac.uk

If you have any further questions, please email me at simon@bioch.ox.ac.uk.
Applications for an account at the UK HGMP-RC should be made to
cbates@hgmp.mrc.ac.uk  Tel: +44 81 869 3446  Fax: +44 81 869 3807

From owner-gdb@net.bio.net Mon Nov 29 22:00:00 1993
Path: biosci!GAS.UUG.ARIZONA.EDU!covingtt
From: covingtt@GAS.UUG.ARIZONA.EDU (Tatiana A Covington)
Newsgroups: bionet.molbio.gdb
Subject: enzymes in glucose pathway to ascorbic acid
Message-ID: <9311301121.AA18560@GAS.uug.Arizona.EDU>
Date: 30 Nov 93 11:21:41 GMT
Sender: daemon@net.bio.net
Distribution: bionet
Lines: 7

I already know the genetic sequence for gulonolactone oxidase, which is the
lAst in the set of 4 which take glucose to ascorbic acid. But the first 3 are,
in order, UDP-glucose dehydrogenase (EC 3.1.1.8), glucoronate reductase
(EC 1.1.1.19), and aldonolactonase (EC 1.1.1.22). Does anyone have any more
info on these--where the genes are, their sequences, enzymology, etc.?
Tatiana Covington
covingtt@gas.uug.arizona.edu

From owner-gdb@net.bio.net Mon Nov 29 22:00:00 1993
Path: biosci!daresbury!doc.ic.ac.uk!warwick!uknet!pipex!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!news.gdb.org!freya.gdb.org!patty
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: new GDB 5.2 online
Message-ID: <1993Nov30.214310.28221@news.gdb.org>
Date: 30 Nov 93 21:43:10 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Organization: Genome Database
Lines: 2
Nntp-Posting-Host: freya.gdb.org

Effective 4:30 pm EST, the new GDB 5.2 has been installed and the data loaded.
It is online for use.

From owner-gdb@net.bio.net Tue Nov 30 22:00:00 1993
Path: biosci!CS.Arizona.EDU!organpipe.uug.arizona.edu!uunet!cs.utexas.edu!howland.reston.ans.net!darwin.sura.net!news.gdb.org!org.gdb!help
From: help@gdb.org
Newsgroups: bionet.molbio.gdb
Subject: Bionet posting - Internet down Dec 2
Message-ID: <1993Dec1.160038.10032@news.gdb.org>
Date: 1 Dec 93 16:00:38 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Followup-To: bionet.molbio.gdb
Organization: The Johns Hopkins University - Genome Data Base (GDB)
Lines: 6
Nntp-Posting-Host: velociraptor.gdb.org


Internet access to GDB unavailable for short time on Thursday Dec. 2
====================================================================

On Thursday December 2, 1993 the SURAnet router which provides Internet access
to GDB will be down for maintenance between 6:00am - 6:30am Eastern Time.

From owner-gdb@net.bio.net Tue Nov 30 22:00:00 1993
Path: biosci!daresbury!keele!uknet!pipex!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!news.gdb.org!sif.gdb.org!ksg
From: GDB User Support
Newsgroups: bionet.molbio.gdb
Subject: GDB 5.2 Release Notes
Message-ID: <1993Dec1.191640.12931@news.gdb.org>
Date: 1 Dec 93 19:16:40 GMT
Sender: news@news.gdb.org
Reply-To: help@gdb.org
Organization: The Johns Hopkins University - Genome Data Base (GDB)
Lines: 642
Nntp-Posting-Host: sif.gdb.org


GDB Release 5.2 Featuring New Output Manager Installed November 29
------------------------------------------------------------------
    
The new GDB release was installed on the computer in Baltimore November 29.
This release of the software features the new Output Manager for user defined
and standard reports. 

A description of how to use Output Manager as well as a summary of other 
enhancements are included in the Release Notes below.
 
For information about accessing GDB, please contact:
 	GDB User Support
 	help@gdb.org



        *****  GDB Version 5.2                29 November 1993 *****

ENHANCEMENTS for ALL USERS

Output        * Output report generation with "look-and feel" of data managers.
Manager         
                The new Output Manager is similar to the data managers with a
                retrieve and a Table/Detail view screen. It has two additional
                screens for defining and scheduling reports. The notes below
                about Output Manager provide details about using each screen.
                
                Output Manager provides all the functions of output in GDB 5.1
                and includes new features. In the following descriptions,
                major new features are marked with =======> .

             *  Two types of reports for output

                Output Manager lets you output two types of reports:

                   User Reports are defined by the user and can include:
                        Retrieved data from any data manager and user management
     =======>           Field Values
     =======>           Online Help topics 
           
                   Standard Reports are generated by GDB staff and include:
                        GDB statistics
                        GDB and OMIM documentation and release notes
                        News about meetings, exhibits, training
                    Note: Chromosome reports in HGM11 report format will be
                          available soon


             *  Overview of Output Manager 

                The following descriptions briefly summarize the Output screens.
                See further below for detailed instructions on using each one.

                   ADD/MODIFY REPORT DEFINITION - define the sub-options 
                        and format of User Reports based on your search 
                        criteria. You cannot modify the content of Standard
                        Reports.

                   SCHEDULE REPORT - define where and when User Reports or
                        Standard Reports will be sent. You can modify your own
                        schedule for Standard Reports.

                   OUTPUT RETRIEVE - use to retrieve User or Standard reports
                        to view on Output Manager screen. You can modify the
			definition and/or schedule of a report by selecting
			an Edit option from Output Manager screen.

                   OUTPUT MANAGER - Table/Detail display of the definition and
                        output schedule of retrieved User or Standard reports.

                Note that to get a report you must 
                   1. define the report (except Standard reports) AND
                   2. schedule the report

                The Output Manager is available from the MAIN MENU and from
                all data managers by selecting TOOL->OUTPUT. If you select
                Output Manager from the MAIN MENU, you will go to the OUTPUT
                RETRIEVE screen. If you select it from any screen within a data
                manager where a retrieve has been defined, you will go to the 
                ADD/MODIFY REPORT DEFINITION screen. 

                You can define and schedule a report without actually
                retrieving data. In any manager, fill in the retrieve screen
                with your search criteria. Instead of retrieving the data,
                select TOOL->OUTPUT from the retrieve screen. Select a sort
                option and you will go to the ADD/MODIFY REPORT DEFINITION 
                screen. The same search results will be available for output
                as if you had retrieved the data and then called Output.


             *  Field Values fields in Output Manager accept single letters.

                To enter a value in any Field Values field on an Output 
                Manager screen, you can just type the unique letter(s) for the
                value you want. The complete value will be filled in when you
                either <Tab> out of the field or select a menu option. 
                To change a value, first erase the current value and then type
                the unique letter(s). Note that the Output Manager is the
                *only* manager in GDB that will accept field values entered
                this way.

                Example from OUTPUT RETRIEVE screen
                        
                   To retrieve your User Reports, type 'u' in the Report
                   Category field -  
                        Report Category: (u                )
                   When you select Retrieve & Sort from the menu, the complete
                   value is displayed -
                        Report Category: (User Reports     )

                You may also select a value through HELP->FIELD VALUES.


             *  ADD/MODIFY REPORT DEFINITION screen for defining user reports

                Use this screen to define new user reports and modify
                previously saved user reports. The Category field will be
                automatically filled in with "User Reports".  

                The information you fill in on this screen will be displayed
                in OUTPUT MANAGER Table/Detail view.

                The following fields let you specify the content and format 
                of the report:

                   Report Name:  free text field - type in a unique name 

     =======>      Include: SQL? include the Sybase SQL query used to
                                 generate the report - default is No
     =======>      Include: Page Brks ?  include page breaks and page headers
                                 in the report - default is Yes

                   Content:      Field Values field for defining the data
                                 includes the following:
                      Retrieve Set:     all objects retrieved by the query
                      Selected Objects: all objects selected from the current
                                          retrieve set
                      Current Object:   only the object where the cursor was
                                          located when entering Output Manager
     =======>         Updates:          only those objects modified or added to
                                          the retrieve set since the last time
                                          the report was generated. The first
                                          time the report is generated, it will
                                          include the entire retrieve set.
                                        The following objects currently do not
                                        support updates: Locus Breakpoint Set,
                                        PCR Condition, Population, Consensus
                                        Map, Field Values, and Online Help.

                                  If you do not select any objects, the default
                                  content is Retrieve Set. If you do select
                                  one or more objects, the default content
                                  is Selected Objects.
                                        
                   Brief Description: free text field - up to 72 characters
                   Detailed Description: free text field - up to 255 characters

                   Sub-Options:  The types of related data available for 
                                 inclusion in a report depend on the data 
                                 manager where you did your retrieve. 
                                 Some data managers have unique data, such as
                                 Abstracts and MeSH Headings for Citation data.
                                 Some types of data, such as Locus, are
                                 available through several managers.

                        The following is part of the sub-options list for 
                        defining reports generated in the Locus Manager.

                        Order            Locus Sub-Options
                          1  [>>] Locus         (Table Format           )
                             [  ] Polym         (Table Format           )
                             [  ] Disorders     (Fixed Format           )
                             [  ] Citation      (Table Format           )

    =======>    The Locus sub-option is already selected with the 
                        number "1" in the Order column. To select additional
                        types of data, <Tab> to the data you want and press
                        <Return>. The sub-options will be numbered in the
                        order you select them, and will appear in your report
                        in this order. If you deselect a sub-option by moving
                        the cursor to it and pressing <Return>, the remaining
                        selected ones will be automatically renumbered.

                        Some sub-options are available in either Table or 
                        Detail format; Table is the default. To change
                        Table to Detail, <Tab> to the format column, erase the
                        current value, and type the letter "d".  Fixed format
                        cannot be changed.

                When you have finished defining the report, select SAVE!
                         
                Once the report is saved, you can select SCHEDULE! to specify
                when and where to send the output. 

    =======>    Note that you can define or modify a report independent of
                scheduling it. You define a report one day and while still
                logged in schedule it to run whenever you want. You can also
                define it one day, log out, and log back in another time to
                schedule it.

                Remember that you *must* schedule the report in order to
                receive it.


             *  SCHEDULE REPORT screen for specifying when/where to send output

                When you enter this screen, the schedule status of your report
                is shown in the upper left corner. The possible statuses are:

                   INACTIVE     report is not currently scheduled
                   WORKING      output program is working on the report
                   WAITING      report is waiting for the next run date
                 + FAILED       report is unable to advance to next run date
                 + GEN-FAILED   report generation has failed
                 + ACC-FAILED   report distribution has failed

                + If you see a report status indicating your report has FAILED,
                  contact GDB User Support.

                The Report Name and Brief Description fields filled in on the
                ADD/MODIFY REPORT DEFINITION screen are displayed on this
                screen but cannot be changed here.

                The information you fill in on this screen will be displayed
                in OUTPUT MANAGER Table/Detail view.

                The Run field is a rotating choice field. Press <Return> to
                cycle through the choices:

                   Once:            runs the report once and saves it (default)
                   Repeating:       runs the report according to your specified
                                        repeat intervals
                   Once and Delete: runs the report once and then deletes it

                If you select Repeating, you must also specify how often you 
                want the report generated. 
                   <Tab> to the Repeat Every field. The number "1" appears
                        as the default in the first half of this field;
                        Month appears as the default in the second half.
                                Repeat Every:  1 [Month]

                   To specify a different number, erase the "1" and type a new
                        number between 1 and 99. 
                   To change to a week-based cycle, <Tab> to the second half of
                        the field and press <Return> to change [Month] to [Week].

                The following three Field Values fields all have default values
                and cannot be blank.

                   Format:      the format of the data or text in the report
                           ASCII text:  all user defined reports
                                        some standard reports
                           PostScript:  some documentation standard reports
                           Tab Delimited: some standard reports
                        When you are scheduling a report, the appropriate
                        format appears as the default in this field.

                   Access Method:  type of output to be generated
                        The available access methods depend on your GDB site
                        and are listed in Field Values.

                        Users accessing GDB at JHU in Baltimore can send output
                        by EMAIL or FTP.

                        Other sites may also provide the PRINT or COPY option.

                   Destination: the specific destination where report will go
                        A default destination is automatically filled in for
                        the Access Method you choose.

                        If you choose EMAIL and you have an email address
                        saved in GDB, it appears in this field. To send
                        the report to a different email address, erase the
                        current address and type in the complete new address.
                        You can email a report to multiple addresses by 
                        separating them with a space or comma.

                        If you choose FTP, the name of the FTP server and the
                        appropriate directory will appear in this field.
                            Example for JHU: ftp.gdb.org/outgoing/

                        You must add a filename after the final "/". Use a
                        filename you will easily recognize when you FTP to that
                        directory.
                            Example: ftp.gdb.org/outgoing/locus-c8.yourname

                Output reports should normally appear at their destination 
                within one day. Small reports will arrive more quickly.


             *  OUTPUT RETRIEVE screen for retrieving User and Standard reports.

                You can define a search for user or standard reports based on a
                variety of data associated with report definitions or schedules.

                   Report Category is a Field Values field for retrieving all
                   the reports in a specified category.
                        "User Reports" will retrieve all your personal reports.
                        The other categories are different types of Standard 
                        Reports and will retrieve all the available reports for
                        that category.

                   You can also retrieve user or standard reports based on the
                   fields on the Detail View screen related to:
                        Report names and descriptions
                        Output schedule and status
                        Output format, method, and specific destination
                        Dates reports were run or modified
                   
                The Retrieve & Sort menu lets you sort the retrieved reports
                by Name, Status, Next Run Date, and Category.


             *  OUTPUT MANAGER screen for displaying retrieved reports

                Table and Detail views of the definition, output schedule, and
                current status of retrieved User or Standard reports. This
                screen displays the information filled in on the ADD/MODIFY
                REPORT DEFINTITION screen and the SCHEDULE REPORT screen.
                To change the definition or the schedule, you must use the
                the appropriate EDIT->MODIFY menu option described below.
                
                This screen includes the following menu options not found on
                the data manager screens.

    =======>        VIEW->SQL QUERY     
                                displays the Sybase SQL query used to generate
                                the report. This information can also be 
                                included in the output report.
                                                                        
                    EDIT->MODIFY->DEFINITION            
                                displays the ADD/MODIFY REPORT DEFINITION
                                screen so you can change the descriptions,
                                sub-options, or format of the report.

                    EDIT->MODIFY->SCHEDULE
                                displays the SCHEDULE REPORT screen so you can
                                change where and/or when the report will be sent.
                        
                    EDIT->DELETE  use to delete the current report where your
                                cursor is located. This deletes the report
                                definition and it cannot be restored.

    =======>        EDIT->UNSCHEDULE  use to cancel either the next or all
                                scheduled output for the current report,
                                without deleting the report itself.


             *  Summary of how to output different types of reports

                To output a NEW user defined report:
                   1. define your search in one of the data managers
                   2. select TOOL->OUTPUT from retrieve or Table/Detail screen
                   3. fill in the ADD/MODIFY REPORT DEFINITION screen and save
                   4. fill in the SCHEDULE REPORT screen and save

                To change the content, format, or output schedule of a 
                previously defined and saved user report:
                   1. select TOOL->OUTPUT from the MAIN MENU or select RETRIEVE
                        from the OUTPUT MANAGER Table/Detail screen.
                   2. from the OUTPUT RETRIEVE screen, retrieve 
                        Category: (User Reports  )
                   3. from the OUTPUT MANAGER screen, select
                        EDIT->MODIFY->DEFINITION - change content and/or format
                                    ->SCHEDULE   - change output schedule
                   4. edit the appropriate fields and save
                        
                To output a standard report:
                   1. from the OUTPUT RETRIEVE screen, enter the unique letter(s)
                        or select HELP->FIELD VALUES from the Category field to
                        enter the appropriate category of standard reports
                   2. from the OUTPUT MANAGER screen, select
                        EDIT->MODIFY->SCHEDULE 
                   3. edit the appropriate fields and save

                To output Field Values or Online Help topics
                   1. from the FIELD VALUES screen or the GDB HELP screen,
                        select TOOL->OUTPUT
                   2. follow the same procedure described above for new
                        user defined reports
                   3. your report will contain the Field Values or the Help 
                        topic displayed when you called output


    =======> *  Save and use session defaults (optional)

                When you change the default values for content, format, or
                output destination, you can save them for the duration of
                your GDB session and use them for other reports.

                Both the REPORT DEFINITION and SCHEDULE REPORT screens have
                a CUSTOMIZE menu.                 
                   CUSTOMIZE->SAVE SESSION DEFAULTS - save current settings
                            ->USE SAVED DEFAULTS    - use saved settings for a
                                                      another report

                On the REPORT DEFINITION screen, defaults can be saved for:
                        Content field
                        Sub-options:  Selection, Order, and Format

                On the SCHEDULE REPORT screen, defaults can be saved for:
                        Run, Repeat Every, Next Run Date,
                        Format, Access Method, Destination

        ---------------------------------------------------------------------
Locus         * Expressed Sequence Tag (EST) numbers now available for loci
Manager
                The EST Number field has been added to the LOCUS RETRIEVE and 
                LOCUS MANAGER (Detail View) screens. The format of these
                numbers is ESTnnnnn, where 'n' is a number.

              * Retrieve reference marker loci
                        
                To retrieve reference markers, set the Reference Marker
                field on the LOCUS RETRIEVE screen to [Yes].    

              * Unassigned loci can be excluded from a query

                To retrieve only loci with an assigned location on *any*
                chromosome, enter 'assigned' or 'asgn' in the Cyto Location
                field.

              * Mitochondrial loci can be retrieved

                To retrieve all the mitochondrial loci, enter 'mt' in the
                Location field.  Cyto Location: mt
                If you sort by location, heavy chain loci sort before light 
                chain loci.

                The format of the location field is:

                        MT[L,H]seqstart-seqend

                     All mitochondrial locations begin with "MT"
                     The third letter is
                           L   for Light Chain
                           H   for Heavy Chain

                     The start and end nucleotide numbers are given as follows:

                        Heavy chains are numbered "clockwise"
                           ex. MTH545-567       MTH"low-high"

                        Light chains are numbered "counterclockwise"
                           ex. MTL260-233       MTL"high-low"

              * Call OMIM with 200 selected loci

                You can select up to 200 loci to send to OMIM.
        ---------------------------------------------------------------------
Probe         * Expressed Sequence Tag (EST) numbers now available for probes
Manager
                The EST Number field has been added to the PROBE MANAGER
                (Detail View) screen. The format of these numbers is ESTnnnnn,
                where 'n' is a number.
        ---------------------------------------------------------------------
Citation      * Citation rank displayed in Table and Detail views
Manager
                When you call Citation Manager from another manager and only
                send one object, the rank of each citation relative to that
                object is now displayed.  

                Table View has a new column, 'R', to display the Rank left of
                the 'Year' column. The Important citation(s) for the object 
                are indicated by an 'I'.  Note that a locus can have two 
                important citations, while all other objects can only have one.

                In Detail View, the Rank field is under the Language field
                and indicates Important, Supportive, or Background.
                
                If you call Citation Manager with more than one object, the
                Rank field does not appear because all citations linked to 
                *any* of the objects are displayed together.

              * Meeting Abstracts available

                Meeting Abstract has been added as a new type of citation.
                To retrieve abstracts, select 'Abstracts' in the Type field
                on the CITATION RETRIEVE screen. The Detail View screen for
                Meeting Abstracts includes the name and dates of the meeting;
                and the country and city where the meeting occurred. 

                If the meeting name is too long to fit on the screen, <Tab>
                to the Meeting field and you will see '>' at the end of the
                text. Press <Return> to see the more text.
                        
                Table View of CITATION MANAGER displays an abbreviation for
                the meeting name; for example, SCWX for Single Chromosome
                Workshop, Chromosome X.
        ---------------------------------------------------------------------
GDB Id        * Count number of GDB IDs before retrieving data
Manager
                The menu option Count! has been added to the GDB Id RETRIEVE
                screen and works the same way as other managers. Fill in
                the retrieve screen and select Count! The total number of
                objects that would be retrieved by your search is displayed.
        ---------------------------------------------------------------------
Contact       * Pre-city post code displayed
Manager
                The PreCity PostCode field has been added to the Detail View
                screen of CONTACT MANAGER.
        ---------------------------------------------------------------------
User Management
              * Output available from User Management

                You can now define and send output reports from User 
                Management. The reports can be for user account records
                actually retrieved or those merely defined on the retrieve
                screen. The reports have the same format as Contact Manager 
                reports.

              * Pre-city post code displayed

                The PreCity PostCode field has been added to the Detail View
                screen of USER MANAGEMENT.
        =====================================================================
ENHANCEMENTS for GDB EDITORS

All           * Edit citation rank from the Edit menu
Manager
                In all managers that can link to citations, there is a new
                edit option on the main manager screen, the edit screen, and
                the Link Manager.
                
                When you select EDIT->CITATION RANK, you will see a table
                view of all the citations linked to the current object.
                The ranks are listed in a rotating choice field on the left:
                I (Important), S (Supportive), or B (Background).
                The important citation(s) are listed first.

                To change the rank of a citation, move the cursor to the field
                and press <Return> to cycle through the options. You can change
                the rank of multiple citations before saving. When you are 
                done, select SAVE!
        ---------------------------------------------------------------------
Locus         * Add GenBank and EST numbers to loci
Manager
                You can now add/modify GenBank numbers and EST numbers for
                genes and DNA segments.

              * Consensus Map feature available

                The description of the how to define a consensus order of
                markers for a chromosome will be distributed to the editors
                by December 1.
        ---------------------------------------------------------------------
Probe         * Add GenBank and EST numbers to probes
Manager
                You can now add/modify GenBank numbers and EST numbers for
                PCR and Cloned probes. You can also add/modify GenBank numbers
                for ASO probes.
        ---------------------------------------------------------------------
Map           * All committees update maps and add/modify map distances
Manager
                All committees (including NC, MDNA, DNA, and MIM) that can add
                maps can now also update them and add/modify map distances. 

              * Zero map distance automatically set to 0

                When the map string indicates that the distance between two 
                loci is zero (denoted by a "/" separating the loci), the entry
                for that pair of loci in the EDIT MAP DISTANCES table is
                automatically set to '0'.
        ---------------------------------------------------------------------
Citation      * Note: Meeting Abstracts cannot be added or modified by the 
Manager         editors. They are entered by GDB staff.
        ---------------------------------------------------------------------
Contact       * Contacts can be deleted
Manager
                You can delete any contact that has not added, modified, or
                been linked to GDB data.
        =====================================================================
PROBLEMS FIXED
All Users:    * In the Locus Manager, you can retrieve loci assigned to a
                linkage group by entering 'ulg' (unassigned linkage group) and
                the number (1-5) of the linkage group in the Location field.

              * When calling the Citation Manager or the GDB Id Manager from
                Polymorphism Manager, all selected Polymorphisms are sent
                to the new manager.

              * The Max Het field in Polymorphism and Probe Managers displays
                the highest heterozygosity value associated with that
                particular polymorphism or probe.

              * In the Cell Line Manager, the Coriell number is correctly
                displayed in the Coriell field.

              * In Map Manager, angle brackets <   > are not displayed
                around the Map Symbol for maps that are not fully approved.
                Use of angle brackets is now consistent in Locus and Map
                Managers; only genes and breakpoint sets which are not fully
                approved have angle brackets.

              * A VIEW STATE screen has been added to the Map Manager.
        =====================================================================
PROBLEMS FIXED
Editors:      

Locus         * The date in the Last Modified field is updated only when a
Manager         field on the MODIFY LOCUS screen is modified. It is not updated
                when objects linked to the locus are modified.
                Note that if you do a Save from the MODIFY LOCUS screen without
                changing any fields, the Last Modified date will still be
                updated.

              * One History record is now generated correctly when a field 
                on the MODIFY LOCUS screen is modified.

                NOTE: the two items above also apply to the other data managers
                that have a Last Modified field or maintain History records.

              * The database can only process one data save command at a time.
                If you are trying to save a new or modified locus or any other
                object at the same time another editor is trying to save a
                different object, you will now get a "Please Note:" message
                describing the situation, rather than Error Code 1205.

              * Breakpoint sets that span multiple chromosomes can now be 
                added. 

              * Loci can be modified regardless of whether they are in an 
                active or deleted map string.

              * The Link button on the ADD/MODIFY DNA SEGMENT screen is now
                greyed/ungreyed correctly.
        ---------------------------------------------------------------------
Citation      * A citation can be deleted by any committee, regardless of
Manager         which committee added it; provided that the citation is not
                the only citation linked to a GDB data object (e.g. locus,
                probe, map) or is included in the most recent HGM/CCM report.
        ---------------------------------------------------------------------
Cell Line Manager
Library Manager
              * All chromosome committees can link and unlink cell lines
                and libraries.

                                - END -

 
 

