From owner-gdb@net.bio.net Wed Jan 04 22:00:00 1995
Newsgroups: bionet.drosophila,bionet.general,bionet.genome.arabidopsis,bionet.genome.chrom22,bionet.genome.chromosomes,bionet.immunology,bionet.info-theory,bionet.jobs,bionet.journals.note,bionet.metabolic-reg,bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.genbank,bionet.molbio.gene-linkage,bionet.molbio.genome-program,bionet.molbio.hiv
Path: biosci!bloom-beacon.mit.edu!gatech!newsfeed.pitt.edu!uunet!xnet!quake.xnet.com!research
From: crta@xnet.com (Norman Fraley)
Subject: New Research & Testing Association Formed
Message-ID: <D1yCKn.2By@amiserv.chi.il.us>
Sender: news@amiserv.chi.il.us
Nntp-Posting-Host: research.crta.org
Organization: Contract Research & Testing Association
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Date: Thu, 5 Jan 1995 20:52:00 GMT
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Xref: biosci bionet.drosophila:777 bionet.general:12714 bionet.genome.arabidopsis:2789 bionet.genome.chromosomes:390 bionet.immunology:2755 bionet.info-theory:3047 bionet.jobs:6983 bionet.journals.note:371 bionet.metabolic-reg:390 bionet.molbio.ageing:1085 bionet.molbio.bio-matrix:526 bionet.molbio.embldatabank:419 bionet.molbio.evolution:2265 bionet.molbio.gdb:273 bionet.molbio.genbank:1873 bionet.molbio.gene-linkage:506 bionet.molbio.genome-program:1101 bionet.molbio.hiv:814

As the primary resource of research information, the Internet was the
primary choice for making all concerned individuals aware of the formation
of the Contract Research & Testing Association.

CRTA is an International Association designed to serve the needs of contract
research, product and process development organizations and consultants
throughout the world.  Contract research organizations have specific public,
governmental, and industry perception and promotion needs which are not addressed
by existing scientific industry associations.  CRTA operates as a non-profit,
tax-exempt, corporation eligible for scientific research and public awareness
charitable organization contributions as provided for in the IRC 501(c)(3) provisions.

Being a scientific research and public awareness related organization, CRTA
exists to benefit its members by providing:

  1) An organization devoted to the promotion of Contract Research.
  2) A unified voice on matters of common interest or concern.
  3) Point of contact for media relations relative to contract research.
  4) Business opportunity referrals as a research clearinghouse.
  5) Professional networking opportunities for its members.
  6) Periodic publishing of information beneficial to the membership.
  7) Periodic dissemination of applicable research results to the public.
  8) Governmental representation on issues affecting CRO's.
  9) Public promotion of the strengths of its membership.
 10) A directory of Contract Research Organizations and Consultants.

CRTA will provide:
  1)  A forum for the exchange of information.
  2)  Formal recognition to the CRO's role in business.
  3)  Standards for the professionals so engaged.
  4)  Representation the profession in matters of common interest.
  5)  The development of techniques and methods to improve the practice and
      management of CROs.

CRTA will also offer:
  1)  A monthly news publication.
  2)  Annual meetings
  3)  Active promotional media publicity programs.
  4)  A professional placement service
  5)  A Contract Research Service Directory.
  6)  Media topics and contacts directory

If you have an interest in joining the Contract Research & Testing Association,
please E-mail your reply to crta@xnet.com.  Please include:

1) The word "membership" in your RE: or header information,
2) Your interest in the association / your area of work,
3) Your dues payment preference (check, money order, credit card, company check, wire xfer, etc.)
   DO NOT INCLUDE ANY CREDIT CARD INFORMATION!  Only your preference for the manner of payment.
4) Most importantly, your email address, and additional contact information if you desire.

We will then e-mail membership information and ALL FURTHER INFORMATION
directly to you at your email location.  Thank you for taking the time
to read this announcement.  If membership in this program this does not
appeal to you, thank you for your patience and understanding.

Sincerely,
Membership Department
Contract Research & Testing Association


Best Regards,

Norman Fraley                                         CRTA@xnet.com
Executive Director                                   BBS:708-515-0494
Contract Research & Testing Association

From owner-gdb@net.bio.net Wed Jan 04 22:00:00 1995
Newsgroups: bionet.molbio.gdb
Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!swrinde!gatech!newsfeed.pitt.edu!uunet!fdn.fr!jussieu.fr!univ-lyon1.fr!swidir.switch.ch!scsing.switch.ch!rzusuntk.unizh.ch!lucas
From: lucas@molbio2.unizh.ch (Lucas Leuzinger)
Subject: Warblefly, Botfly or Dermatobia sp. ????
Message-ID: <1995Jan5.184441.24374@rzu-news.unizh.ch>
Sender: newsadm@rzu-news.unizh.ch (CNEWS ADMINISTRATION)
Organization: University of Zurich, Switzerland
X-Newsreader: TIN [version 1.2 PL2]
Date: Thu, 5 Jan 1995 18:44:41 GMT
Lines: 19


Hi !

I need for my diploma-thesis some or any information about the BOTFLY or the
WARBLEFLY,  Dermatobia hominis (Oestridae), that live in warm Central- and
Southamerica ...

Do you know any specialist or person working on this subject, or parasitic
flies in general ???, any source of information ???

I'm very grateful for any kind of help !!!

Please write me : Lucas Leuzinger 
		  lucas@molbio2.unizh.ch

Thanks a lot!




From owner-gdb@net.bio.net Wed Jan 04 22:00:00 1995
Path: biosci!bloom-beacon.mit.edu!uhog.mit.edu!nntp.club.cc.cmu.edu!newsfeed.pitt.edu!uunet!fonorola!inforamp.net!woody16.inforamp.net!intermed
From: intermed@inforamp.net (Ian Clarke)
Newsgroups: bionet.molbio.gdb
Subject: Attention Canadian Researchers
Date: Thu, 5 Jan 1995 12:54:54
Organization: InfoRamp Inc.
Lines: 19
Message-ID: <intermed.38.000CEAAD@inforamp.net>
NNTP-Posting-Host: woody16.inforamp.net
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

Inter Medico is the Canadian distributor for many of the world's leading 
molecular biology companies. Inter Medico represents Genzyme(cytokines, 
chemokines, cell adhesion molecules), Novagen (pET bacterial expression 
systems, mRNA purification systems), Amresco (fine chemicals, thermostable DNA 
polymerases, nucleic acid isolation kits), SLT (ELISA readers, fluorometers, 
microplate washers), BioDesign (a huge selection of biologically important 
antibodies), and The Binding Site ( clinically-relevant antibody-based 
diagnostic systems).

As part of Inter Medico's continuing dedication to the Canadian research 
community, we have established a user-group to share the latest information 
about molecular biology products designed to save you time and money. There 
are valuable discounts available only to subscribers.

There is no charge to join. If you are interested in joining, please send an 
e-mail message to Majordomo@inforamp.net. In the body of the letter, type 
Subscribe Research <your e-mail address>.

Join today, and start enjoying the benefits immediately.

From owner-gdb@net.bio.net Thu Jan 12 22:00:00 1995
Newsgroups: bionet.molbio.gdb
Path: biosci!ns1.faseb.org!darwin.sura.net!news.gdb.org!news
From: help@gdb.org (GDB User Support)
Subject: GDB Unavailable Jan 19 during 5.5.1 installation
Message-ID: <1995Jan13.194940.10786@news.gdb.org>
Sender: news@news.gdb.org
Nntp-Posting-Host: sif.gdb.org
Reply-To: bionet.molbio.gdb
Organization: The Johns Hopkins University - Genome Data Base (GDB)
Date: Fri, 13 Jan 1995 19:49:40 GMT
Lines: 19

GDB Release 5.5.1 is scheduled to be installed on the computer at Johns Hopkins
University in Baltimore on Thursday January 19. The following services will be
unavailable on this day from 8:00am to 12 noon Eastern Time while the database
is converted:

	GDB at JHU
	GDB Browser on WWW

When the new GDB software has been installed, we will post the release notes
describing the enhancements included in the release.

For information about accessing GDB, please contact:
	GDB User Support
	help@gdb.org






From owner-gdb@net.bio.net Sun Jan 15 22:00:00 1995
Newsgroups: bionet.molbio.gdb
Path: biosci!agate!howland.reston.ans.net!EU.net!sun4nl!sci.kun.nl!davidf
From: davidf@caos.kun.nl (David Featherstone)
Subject: GDB & OMIM Training via WWW
Message-ID: <D2HzG5.1K5@sci.kun.nl>
Sender: news@sci.kun.nl (News owner)
Nntp-Posting-Host: cammsg1.caos.kun.nl
Organization: CAOS/CAMM
X-Newsreader: TIN [version 1.2 PL0]
Date: Mon, 16 Jan 1995 12:16:53 GMT
Lines: 59

                    GDB & OMIM On-line Training
                              via the
                           World Wide Web

Dear Users of GDB and OMIM;

	We are pleased to announce our on-line training course for
GDB & OMIM.  If you have a WWW browser on your workstation, PC or
Macintosh, simply point it to:

	http://www.caos.kun.nl/genomics/GDB_OMIM_TOC.html

and begin!

	The course can be taken in two modes: interactively, with
a parallel GDB or OMIM session, so you may try the commands as they
are described, or passively, reading and looking at the results shown
in the screen "snap-shots" included on the pages. I recommend the
interactive mode.

	Users attempting the entire course, trying the examples and
checking the results, should set aside about six hours. Further, I
suggest using three hours on each of two days.

	This course is continually updated. I try to make certain
the answers to the example questions are current with the databases,
but with daily updates to the databases, you might notice some
differences between my answers and yours. Please TELL ME when you
find a discrepancy, and I'll correct it!

	Finally, please note that I have tried to take full advantage
of the graphics capabilities of most WWW servers; if you find yourself
on a S L O W connection to our facility, and the pages take
inconveniently long to load, try turning OFF the "automatic image
loading" feature of your WWW client. For example, in the Options
menu of NCSA Mosaic, select
	"Delay Image Loading".
In Mosaic Netscape, go to the Options menu and de-select
	"Auto Load Images".
Those of you using Lynx, the text-only WWW browsing tool, will miss
the graphics, of course, but can compensate by printing the pages
and using them to guide you through an active GDB or OMIM session.

	Best of luck, and please contact me with suggestions for
improvements!

David Featherston

============================================================================
David Featherston
Research Geneticist &					CAOS/CAMM Center,
	Computational Genetics Consultant		P.O. Box 9010,
davidf@caos.kun.nl					6500 GL, Nijmegen
dwf11@phx.cam.ac.uk					The Netherlands
dfeather@hgmp.mrc.ac.uk					+31 (0)80 653383 tlf
http://www.caos.kun.nl/davidf.html			+31 (0)80 652977 FAX
	--------------------------------------------------------
	The CAOS/CAMM Center is the Dutch GDB Node & EMBnet Node
============================================================================

From owner-gdb@net.bio.net Wed Jan 18 22:00:00 1995
Path: biosci!GDB.ORG!ksg
From: ksg@GDB.ORG (Kay Gottesman)
Newsgroups: bionet.molbio.gdb
Subject: GDB Release 5.5.1 installed Jan 19 at Johns Hopkins University
Date: 19 Jan 1995 12:01:28 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 95
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9501191958.AA28993@dev.gdb.org>

--------------------------------------------------------------------------
	GDB Release 5.5.1 Installed January 19 at JHU
--------------------------------------------------------------------------

The new GDB release installed at Johns Hopkins University in Baltimore
January 19 includes the enhancements summarized in the Release Notes below.

People with GDB/Accessor-5.2 on their Macs should be able to continue using
Accessor-5.2 with the new GDB 5.5.1.

For information about accessing GDB, please contact:
	GDB User Support
	help@gdb.org



	*****  GDB Version 5.5.1		January 19, 1995 *****

This is a minor release which includes bug fixes and the following
enhancements.

ENHANCEMENTS for ALL USERS

Probe	      * Retrieve PCR probes by STS status
Manager
		The Probe Retrieve screen now includes an STS Flag field
		with options [Any, Yes, No], so you can retrieve PCR probes
		based on whether or not they are a Sequenced Tagged Site 
		(STS).
	---------------------------------------------------------------------
Locus         * Retrieve Locus MIM numbers and Disorder MIM numbers
Manager
		The MIM Number field on the Locus Retrieve screen now
		retrieves loci associated with the MIM numbers directly
		and also loci indirectly associated with the MIM numbers
		though MIM disorders.  Previously this field only retrieved
		loci directly associated with the MIM numbers.

	=====================================================================
ENHANCEMENTS for GDB EDITORS

Citation      * Published status has default value "Published"
Manager
		On the Add/Modify Citation screen for journals and book,
		the Published field includes the options:  

			Published (default)
			In Press
			Submitted

		When you enter the screen, the default "Published" is
		automatically filled in.  To change the value, select
		Help->Field Values.

		In GDB 5.5, the default "Published" was not displayed on
		the Add/Modify Citation screen. In GDB 5.4 the field had
		been a Rotating Choice field with options Yes (default
		displayed) and In Press.
	-------------------------------------------------------------------
Messages      * Citations in DB Object field include GDB Id numbers

		The Detail View of messages associated with specific
		citations now includes the GDB Id number of the citation
		in addition to the first author and year. This additional
		information lets you distinguish between different citations
		which have the same first author and year.
	-------------------------------------------------------------------
Locus	      * Associate MIM Disorder Number with Disorder Name
Manager
		On the Edit Disorders screen you can now include a MIM
		Disorder Number associated with a specific MIM Disorder 
		Name. Previously you could only enter the Disorder Name.

		The number and name fields work together as follows:

		  . A disorder can have a name only, but a disorder number 
			must have an associated name.
		  . If you enter a number and the name field is empty, the
			name will automatically be filled in, if available.
			If no name is filled in, you must enter one.
		  . If you enter a number and a name is already there, the
			existing name will remain.

		Note that since retrieving loci by MIM numbers now also
		checks for MIM disorder numbers (as described above), you
		should enter only Locus MIM Numbers on the Add and Modify
		screens, and let the Disorder Numbers be added on the
		Edit Disorders screen.

	===================================================================
PROBLEMS FIXED
All Users:    * In the Citation Manager, all users can select VIEW->LINKS
		to see the objects linked to a specific citation.

				- END -

From owner-gdb@net.bio.net Tue Jan 24 22:00:00 1995
Newsgroups: bionet.molbio.gdb
Path: biosci!ns1.faseb.org!darwin.sura.net!news.gdb.org!news
From: help@gdb.org (GDB User Support)
Subject: GDB/OMIM unavailable Jan 25th at JHU due to Internet problem
Message-ID: <1995Jan25.214613.10775@news.gdb.org>
Sender: news@news.gdb.org
Nntp-Posting-Host: sif.gdb.org
Reply-To: bionet.molbio.gdb
Organization: The Johns Hopkins University - Genome Data Base (GDB)
Date: Wed, 25 Jan 1995 21:46:13 GMT
Lines: 13

GDB and OMIM at Johns Hopkins University were unavailable on Wednesday 
January 25th due to problems at our Internet provider (SURAnet).

We apologize for any inconvenience this may have caused.

For information about GDB and OMIM, please contact:
	GDB User Support
	Genome Data Base
    	help@gdb.org





From owner-gdb@net.bio.net Sun Jan 29 22:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!ix.netcom.com!netcom.com!csus.edu!news.ucdavis.edu!rocky!ez006804
From: Phandaal <ez006804@peseta.ucdavis.edu>
Newsgroups: bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.gene-linkage,bionet.molbio.genome-program,bionet.molbio.hiv,bionet.molbio.rapd,bionet.molbio.yeast
Subject: controversies & ethics
Date: Mon, 30 Jan 1995 11:59:15 -0800
Organization: University of California, Davis
Lines: 37
Message-ID: <Pine.SOL.3.91.950130115343.5258D-100000@rocky>
NNTP-Posting-Host: rocky.ucdavis.edu
Mime-Version: 1.0
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Xref: biosci bionet.molbio.ageing:1203 bionet.molbio.bio-matrix:531 bionet.molbio.embldatabank:430 bionet.molbio.evolution:2374 bionet.molbio.gdb:279 bionet.molbio.gene-linkage:513 bionet.molbio.genome-program:1135 bionet.molbio.hiv:850 bionet.molbio.rapd:949 bionet.molbio.yeast:2260

I've been asked to give a lecture to upper-division college students on
the controversies and ethical considerations in producing transgenic
organisms, especially transgenic plants.  It's been a while since I gave
this lecture, and so I was wondering if anybody had any good examples of
controversies or ethical considerations that I could incorporate into the 
talk.

Two I can think of off-hand are:

1) introducing insecticidal proteins (such as the Bacillus thuringiensis
protein) into plants may create resistant insect populations (under the
force of heavy selection pressure), which could then overrun the resistant
plants and make worthless the efforts by conventional growers who *use* Bt
protein as a topical pesticidal spray. 

2) altering fatty acid metabolism in oil-crops (like canola) so that they 
produce oils found chiefly in palm and coconut could severely damage the 
palm oil and coconut oil industries in Third World countries... thus 
severely depressing the economies of these already struggling countries.

If you are aware of any other similar cases, or simply have a point which 
you think would be useful for the lecture, I'd appreciate hearing from 
you!

Thanks,

Peter Schuerman
plschuerman@ucdavis.edu

/>>/>>/>>      In nature there are neither rewards nor       <<\<<\<<\
\>>\>>\>>      punishments--there are consequences.          <</<</<</
<<\<<\<<\                                                    />>/>>/>>
<</<</<</                          - Robert G. Ingersoll     \>>\>>\>>





From owner-gdb@net.bio.net Mon Jan 30 22:00:00 1995
Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!swiss.ans.net!emi.com!pauling.wadsworth.org!rebecca!labonnes
From: labonnes@csc.albany.edu (S. LaBonne)
Newsgroups: bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.gene-linkage,bionet.molbio.genome-program,bionet.molbio.hiv,bionet.molbio.rapd,bionet.molbio.yeast
Subject: Re: controversies & ethics
Date: 31 Jan 1995 01:21:34 GMT
Organization: University at Albany, SUNY
Lines: 39
Message-ID: <3gk3au$pdp@rebecca.albany.edu>
References: <Pine.SOL.3.91.950130115343.5258D-100000@rocky>
NNTP-Posting-Host: freia.albany.edu
Xref: biosci bionet.molbio.ageing:1206 bionet.molbio.bio-matrix:532 bionet.molbio.embldatabank:431 bionet.molbio.evolution:2376 bionet.molbio.gdb:280 bionet.molbio.gene-linkage:514 bionet.molbio.genome-program:1138 bionet.molbio.hiv:851 bionet.molbio.rapd:950 bionet.molbio.yeast:2266

In article <Pine.SOL.3.91.950130115343.5258D-100000@rocky>,
Phandaal  <ez006804@peseta.ucdavis.edu> wrote:
>I've been asked to give a lecture to upper-division college students on
>the controversies and ethical considerations in producing transgenic
>organisms, especially transgenic plants.  It's been a while since I gave
>this lecture, and so I was wondering if anybody had any good examples of
>controversies or ethical considerations that I could incorporate into the 
>talk.
>
>Two I can think of off-hand are:
>
>1) introducing insecticidal proteins (such as the Bacillus thuringiensis
>protein) into plants may create resistant insect populations (under the
>force of heavy selection pressure), which could then overrun the resistant
>plants and make worthless the efforts by conventional growers who *use* Bt
>protein as a topical pesticidal spray. 
>
>2) altering fatty acid metabolism in oil-crops (like canola) so that they 
>produce oils found chiefly in palm and coconut could severely damage the 
>palm oil and coconut oil industries in Third World countries... thus 
>severely depressing the economies of these already struggling countries.

My problem with these examples is that I see nothing about them that
is unique to transgenic technology.  Similar sorts of problems are
raised all the time by "conventional" technologies, including very
ancient ones like selective breeding.  An analogue to 1 is simply
overuse of pesticides (or antibiotics for that matter), which can
render them worthless in the way you describe.  And 2 in no way
raises ethical issues different from, say, starting a palm oil
industry in Key West, possibly after selective breeding of oil
palms to produce strains that give high yields there.

Indeed, I doubt that there _are_ any ethical issues which depend
_specifically_ on agricultural use of biotechnology as opposed
to agricultural technologies in general.  

-- 
Steve LaBonne *********************** (labonnes@csc.albany.edu)
"It can never be satisfied, the mind, never." - Wallace Stevens

From owner-gdb@net.bio.net Mon Jan 30 22:00:00 1995
Newsgroups: bionet.molbio.gdb
Path: biosci!ns1.faseb.org!darwin.sura.net!nih-csl!helix.nih.gov!luism
From: "Luis M. Alvarez" <luism@helix.nih.gov>
Subject: mammalian cells transfection
Content-Type: TEXT/PLAIN; charset=US-ASCII
Message-ID: <Pine.SGI.3.91.950131141111.7686A-100000@helix.nih.gov>
Sender: postman@alw.nih.gov (AMDS Postmaster)
Organization: National Institutes of Health
Mime-Version: 1.0
Date: Tue, 31 Jan 1995 19:16:38 GMT
Lines: 14


Hi!

Do anyone have a protocol for coupling poly-L-lysine to adenovirus particles?
I am trying to perform receptor-mediated transfection of mammalian 
cells, but for some reason this protocol seems quite a bit elusive.

Thank you.

Dr. Luis M. Alvarez-Salas
Lab. of Biology
NCI/NIH
luism@helix.nih.gov


From owner-gdb@net.bio.net Mon Jan 30 22:00:00 1995
Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!pipex!uunet!news.u.washington.edu!roach
From: roach@u.washington.edu (Jared Roach)
Newsgroups: bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.gene-linkage,bionet.molbio.genome-program,bionet.molbio.hiv,bionet.molbio.rapd,bionet.molbio.yeast
Subject: Re: controversies & ethics
Date: 31 Jan 1995 20:52:25 GMT
Organization: University of Washington
Lines: 28
Message-ID: <3gm7u9$t5e@nntp1.u.washington.edu>
References: <Pine.SOL.3.91.950130115343.5258D-100000@rocky> <3gk3au$pdp@rebecca.albany.edu>
NNTP-Posting-Host: saul3.u.washington.edu
Xref: biosci bionet.molbio.ageing:1212 bionet.molbio.bio-matrix:533 bionet.molbio.embldatabank:432 bionet.molbio.evolution:2379 bionet.molbio.gdb:282 bionet.molbio.gene-linkage:515 bionet.molbio.genome-program:1140 bionet.molbio.hiv:853 bionet.molbio.rapd:951 bionet.molbio.yeast:2273

While it is true that there is to a first approximation
nothing that one can do with transgenic agriculture that could not
be done with traditional plant breeding, there is no denying that
recombinant DNA is MUCH faster.
        This to me is the crux of the ethical issue. Not what, or
even why, but how fast.  It would presumably take a very long time
to breed arctic fish with strawberries to get frost resistant
strawberries (or more likely, to select over umpteen generations
of strawberries for the same trait).
        Now one might argue that the speed of recombinant research
has two dangers:
        1) The rest of the ecosystem is not changing as fast to
modify itself so as to maintain some kind of ecological "balance."
Furthermore, scientists may be slower to understand ecological impact
than they are in developing new organisms.
        2) The human race as a whole (or national governments, or
individuals) is slow to reach consensus on ethical issues (i.e.
religion, abortion, the creation of new species, etc.)  Science
should slow its pace of discovery to allow Ethics to catch up.
 
        There are excellnt counterpoints, but I will allow others
to continue the dialectic.

Jared Roach
Dept. of Molecular Biotechnology
University of Washington
roach@u.washington.edu


From owner-gdb@net.bio.net Tue Jan 31 22:00:00 1995
Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!swiss.ans.net!emi.com!pauling.wadsworth.org!rebecca!labonnes
From: labonnes@csc.albany.edu (S. LaBonne)
Newsgroups: bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.gene-linkage,bionet.molbio.genome-program,bionet.molbio.hiv,bionet.molbio.rapd,bionet.molbio.yeast
Subject: Re: controversies & ethics
Date: 1 Feb 1995 00:39:33 GMT
Organization: University at Albany, SUNY
Lines: 37
Message-ID: <3gml85$fb5@rebecca.albany.edu>
References: <Pine.SOL.3.91.950130115343.5258D-100000@rocky> <3gk3au$pdp@rebecca.albany.edu> <3gm7u9$t5e@nntp1.u.washington.edu>
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In article <3gm7u9$t5e@nntp1.u.washington.edu>,
Jared Roach <roach@u.washington.edu> wrote:

>        Now one might argue that the speed of recombinant research
>has two dangers:
>        1) The rest of the ecosystem is not changing as fast to
>modify itself so as to maintain some kind of ecological "balance."
>Furthermore, scientists may be slower to understand ecological impact
>than they are in developing new organisms.

This is not an ethical issue until the ecological problems are
shown to be more concrete than vague forebodings.  Even then,
it is not an ethical problem of a new _kind_, being nothing
more than the familiar tradeoffs between benefits and environmental
impact that must be considered in the case of virtually _any_
technological change.

>        2) The human race as a whole (or national governments, or
>individuals) is slow to reach consensus on ethical issues (i.e.
>religion, abortion, the creation of new species, etc.)  Science
>should slow its pace of discovery to allow Ethics to catch up.

There is much to be said for this contention, but again biotechnology
is not unique in giving rise to such considerations.

I still say there are _no_ ethical considerations that are _unique to
biotechnology as such_, and I fail to see the case for singling out
biotechnology in an ethics course; what's more, this tends to give
scientifically naive students, and members of the public, an
irrational fear of biotechnology over and above other technologies.
Naturally, biotechnology can serve as a valuable source of _examples_
in discussions of the ethics of applying new technologies in general.


-- 
Steve LaBonne *********************** (labonnes@csc.albany.edu)
"It can never be satisfied, the mind, never." - Wallace Stevens

From owner-gdb@net.bio.net Tue Jan 31 22:00:00 1995
Path: biosci!daresbury!trane.uninett.no!sunic!pipex!pipex!howland.reston.ans.net!news2.near.net!das-news2.harvard.edu!casaba.srv.cs.cmu.edu!bb3.andrew.cmu.edu!andrew.cmu.edu!hb10+
From: "Howard M. Bomze" <hb10+@andrew.cmu.edu>
Newsgroups: bionet.molbio.ageing,bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.genome-program,bionet.molbio.hiv,bionet.molbio.rapd,bionet.molbio.yeast,bionet.molbio.gene-linkage
Subject: Re: controversies & ethics
Date: Wed,  1 Feb 1995 17:31:58 -0500
Organization: Doctoral student, Biology, Carnegie Mellon, Pittsburgh, PA
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References: <Pine.SOL.3.91.950130115343.5258D-100000@rocky> <3gk3au$pdp@rebecca.albany.edu> <3gm7u9$t5e@nntp1.u.washington.edu>
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Xref: biosci bionet.molbio.ageing:1221 bionet.molbio.bio-matrix:535 bionet.molbio.embldatabank:434 bionet.molbio.evolution:2387 bionet.molbio.gdb:284 bionet.molbio.genome-program:1144 bionet.molbio.hiv:858 bionet.molbio.rapd:953 bionet.molbio.yeast:2278 bionet.molbio.gene-linkage:518

   Steve Bonne has been saying that there are no new ethical
considerations for agricultural biotechnologies.  However, he has been
missing one very important one, that is the possibility of an engineered
gene to be transfered to a different species.  The transgenic plant not
only has the sequences of the desired gene, it also contains the
sequences which are necesary to insert the gene into the genome.  So a
question which must be looked at is this:  If a gene for herbicide
resistance has been put into a corn plant so that that herbicide can be
used to kill all of the crab grass in the corn field, what happens if
the gene is transfered to the crab grass?  There are also ethical
problems with other non-agricultural biotechnology.


Howard Bomze
 

