From owner-genome-program@net.bio.net Mon Feb 03 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: Peter Karp <pkarp@ai.sri.com>
Newsgroups: bionet.molbio.genome-program
Subject: ISMB-97 paper deadline extended
Date: 4 Feb 1997 14:48:02 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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    ** Extension of ISMB-97 Paper Submission Deadline **

The ISMB organizers are extending the deadline for submission
of ISMB-97 papers.  If you wish to take advantage of the extended
deadline, please:

o Submit the following information by email to gaasterl@mcs.anl.gov
  in a message whose subject is "ISMB extension":
   - Title
   - Authors
   - Abstract
  This information must be received by Friday, Feb 7.

o Submit a hardcopy version of your paper to EBI to be received
  by Wednesday, Feb 12, at the standard submission address listed
  on the ISMB WWW page.  E-mail paper submissions will not be
  accepted for this extended deadline.

If at all possible, please try to meet the earlier deadline of
submitting the paper by Friday, Feb 7.

Peter Karp




From owner-genome-program@net.bio.net Tue Feb 04 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: pdxrmb@vaxb.ccc.nottingham.ac.uk
Newsgroups: bionet.molbio.genome-program
Subject: Human Genetic Variation conferences.
Date: 5 Feb 1997 10:36:06 -0800
Organization: University of Nottingham, UK
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Hi netters'
		I'm lookig for a conference on Human Molecular Genetics to
attend in the summer. My primary interest is in the origin and maitainance
of human genetic varation, as well as general human genome research. If any
conference organisers are out there, or you have advance warning about such a
meeting I would very much appreciate an email.

Thanks in Advance.
			Richard M Badge.



From owner-genome-program@net.bio.net Wed Feb 05 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: bkq@ornl.gov (Betty K Mansfield)
Newsgroups: bionet.molbio.genome-program
Subject: Re: Human Genetics conferences.
Date: 5 Feb 1997 18:07:27 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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Richard,

For starters, check out the calendar of genetic events at:
http://www.ornl.gov/TechResources/Human_Genome/CAL.HTML

The following Gordon Research Conference is held August 
10-15. Human Molecular Genetics; Newport, RI [GRC, 401/783-4011, Fax:
-7644, grc@grcmail.grc.uri.edu, http://www.grc.uri.edu/] 


Then check out the Training calendar at:
http://www.ornl.gov/TechResources/Human_Genome/TRCAL.HTML

Hope there is something useful for you on one of these calendars. 
---Betty



At 11:18 AM 2/5/97 +0000, you wrote:
>Hi netters'
>		I'm lookig for a conference on Human Molecular Genetics to
>attend in the summer. My primary interest is in the origin and maitainance
>of human genetic varation, as well as general human genome research. If any
>conference organisers are out there, or you have advance warning about such a
>meeting I would very much appreciate an email.
>
>Thanks in Advance.
>			Richard M Badge.


From owner-genome-program@net.bio.net Wed Feb 05 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: "X=--> aLeX jOsIaH tAn  <s4464182@mercury.np.ac.sg>"@triton
Newsgroups: bionet.molbio.genome-program
Subject: Beta - gluc gene of E.coli ..!
Date: 6 Feb 1997 05:48:36 -0800
Organization: Ngee Ann Polytechnic, Singapore
Lines: 18
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hi all who read this mail..!!
there is a few qns just like to ask..!!
1)do plant have any basal lvl of expressing beta-gluc the enzymes..??
cos we r doing a project abt using this beta-gluc gene...!!
this gene is orginated from the bacteria E.coli.
so i was wondering if plant will have the gene if this bacteria..??

2)do acetosyringone will be able to enhance the infectivity of
Agrobacterium..??....

thank for the comment..!
pls reply to this address..!!
s4464182@np.ac.sg
thank a lot..& have a good day..!!




From owner-genome-program@net.bio.net Thu Feb 06 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: Computer Contact-Carlos Enrile <ccontact@isid.es>
Newsgroups: bionet.molbio.genome-program
Subject: Jornadas Genoma y Etica
Date: 7 Feb 1997 13:22:21 -0800
Organization: Unisource Espana NEWS SERVER
Lines: 8
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Jornadas de Reflexi=F3n sobre el Genoma  Humano
Fundacion Ramon Areces
Madrid, Febrero de 1997

Mas informaci=F3n en:
http://ourworld.compuserve.com/homepages/computercontact/conghom.htm



From owner-genome-program@net.bio.net Thu Feb 06 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: bkq@ornl.gov
Newsgroups: bionet.molbio.genome-program
Subject: Biomarkers, the Genome & the Individual---
Date: 7 Feb 1997 15:51:25 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
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                             TENTATIVE  MEETING OUTLINE

                  BIOMARKERS, THE GENOME & THE INDIVIDUAL---

         WORKPLACE AND MEDICAL IMPLICATIONS OF A RAPIDLY EVOLVING
                                TECHNOLOGY

                        Charleston, South Carolina
                               May 4-8, 1997

SUNDAY MAY 4 (The Francis Marion Hotel, Charleston)

4-7 PM    Registration
7 PM      Keynote address: Dr. Joshua Lederberg* (Nobel Laureate)
8 PM      Reception
                           ____________________


MONDAY MAY 5 (Physicians Memorial Auditorium-The College of Charleston)

SECTION:  INTRODUCTION AND BACKGROUND

                Session Chairman:  Dr. Lawrence Mohr*, MUSC

8:20 AM   Special Announcements
8:30 AM   Introduction and Goals (Dr. Lawrence Mohr*, MUSC)
8:45 AM   What is a Valid Biomarker ? (Dr. Paul Schulte*, NIOSH)
9:05 AM   Historical Perspectives (Dr. Michael Gochfeld*, EOSHI)
9:25 AM   Laboratory Perspectives (Dr. Rogene Henderson*, ITRI)

9:45 AM   Panel Discussion:  (Chair:  Dr. Carol Henry*, DOE)

10:15 AM  COFFEE BREAK

10:45 AM  Clinical Perspectives (Dr. Robert McCunney*, MIT)
11:05 AM  Ethical Perspectives (Dr. Tom Murray*, Case Western)
11:25 AM  Public Policy and Costs (Dr. Bernard Goldstein*, EOSHI)

11:45 AM  Panel Discussion:  (Chair:  Dr. Paul Schulte*, NIOSH)

12:15 PM  LUNCH BREAK

SECTION:  TECHNOLOGIES FOR MEASURING PRIOR EXPOSURES

               Session Chairman:  Dr. Mort Mendelsohn*, LLNL

1:30 PM   Technical Basis for ESR dosimetry (Dr. Marc Desrosiers*, NIST)
1:50 PM   Validation of ESR in the Atomic Bomb Survivors Studies (Dr.
          Nori Nakamura*, RERF, Japan)
2:10 PM   X-ray Fluorescence (Dr. Howard Hu*, Harvard)

2:30 PM   Panel Discussion:  (Chair:  Dr. Dieter Regulla*, GSF, Munich,
          Germany)

3:00 PM   COFFEE BREAK

3:30 PM   Stable Chromosomal Aberrations (Dr. Jim Tucker*, LLNL)
3:50 PM   Immune Biomarkers (Dr. Bob Vogt*, CDC)
4:10 PM   Isotopic Ratios (Dr. Joseph Graziano*, Columbia)

4:30 PM   Panel Discussion:  (Chair:  Dr. Bernard Goldstein*, EOSHI)

SECTION:       STORAGE OF DNA SAMPLES

           Session Chairman:  Dr. Mark Rothstein*, U. of Houston

5:00 PM   Large Scale Genomic Tagging at DOD (Dr. Victor Weedn*, AFIP)
5:20 PM   Issues Related to the Re-analysis of Stored Samples (Dr. Ellen
          Clayton*, Vanderbilt Medical School)

5:40 PM   Panel Discussion:  (Chair:  Dr. Eula Bingham*, U. of Cincinnati)
                           ____________________


TUESDAY MAY 6 (Physicians Memorial Auditorium-The College of Charleston)

SECTION:  TECHNOLOGIES FOR MEASURING RECENT EXPOSURES

         Session Chairman:  Dr. Richard Albertini*, U. of Vermont

8:20 AM   Special Announcements
8:30 AM   Volatile Chemicals and the E2R Monitor (Dr. Karla Thrall*, PNL)
8:50 AM   Tubular Proteinurea (Dr. Richard Wudeen*, New Jersey)
9:10 AM   DNA Adducts (Dr. Kari Hemminki*, Karolinska, Sweden)

9:30 AM   Panel Discussion:  (Chair:  Dr. Leopold Miksche*, Bayer AG,
          Germany)

10:00 AM  COFFEE BREAK

10:30 AM  DNA Adducts using Accelerator Mass Spec (Dr. Ken Turtletaub*,
          LLNL)
10:50 AM  Protein/haemoglobin Adducts for TCE exposure (Dr. David
          McMillan*, MUSC)

11:10 AM  Panel Discussion:  (Chair:  Dr. Mort Mendelsohn*, LLNL)

SECTION:  BIOMARKERS OF METABOLIC SUSCEPTIBILITY

            Session Chairman:  Dr. Paul Brandt-Rauf*, Columbia

11:30 AM  P 450 and Chemical Metabolism (Dr. Peter Shields*, NCI)
11:50 PM  Acetylation-Related Susceptibilities of Metabolism (Dr. F.
          Kadlubar*, NCTR)
12:10 PM  Glutathione S-transferase (Dr. Brian Ketterer*, UK)

12:30 PM  Panel Discussion:  (Chair:  Dr. Roger McClellan, CIIT)

1:00-2:00 PM   LUNCH BREAK

SECTION:  GENOMICS AND TECHNOLOGY DEVELOPMENTS

            Session Chairman: Dr. Lee Hood*, U. of Washington

2:00 PM   Scientific Basis of Genomic Technologies (Dr. Lee Hood*, U. of
          Washington)
2:20 PM   High Density DNA Chip Arrays (Dr. Rob Lipshutz*, Affymetrix)
2:40 PM   mRNA and the Analysis of Expressed Genes (David Botstein,
          Stanford)

3:00 PM   Panel Discussion:  (Chair: Dr. Marvin Frazier*, DOE)

3:30 PM   COFFEE BREAK

4:00 PM   Lab-on-a-chip (Dr. Lawrence A. Bock, Caliper Technologies)
4:20 PM   Mass Spectra DNA Tags for Multiplex Sequencing (Dr. George Church,
          Harvard)
4:40 PM   Biomarker Potential of PCR (Dr. Glen Evans*, U. of Texas)

5:00 PM   Panel Discussion:  (Chair:  Dr. Elbert Branscomb*, LLNL)

                           ____________________

7-9:00 PM POSTERS AND DISPLAYS (Cash Bar) -The Francis Marion Hotel

Progress in Diagnostics Kit Technology for Screening for Susceptibility:

o    Large pharmaceutical companies (Bayer AG*, Glaxo Wellcome, Smith-
     Kline, Merck, Pfizer)
o    Other companies:    Monsanto, Sequana Therapeutics, Nanogen, Hyseq,
                    Pharmacia Biotech, Vysis, Amgen, etc.

                           ____________________


WEDNESDAY MAY 7 (Physicians Memorial Auditorium-The College of Charleston)

SECTION:  PRACTICAL APPLICATIONS OF BIOMARKERS

          Session Chairman:  Dr. Barry Johnson*, Director, ATSDR

8:20 AM   Special Announcements
8:30 AM   Practical Uses of Biomarkers in Population Studies (Dr. Geoffrey
          Howe*, Columbia)
8:50 AM   Beryllium Biomarkers (Dr. Lee Newman*, National Jewish)
9:10 AM   Biomarkers for Aflatoxin (Dr. Regina Santella*, Columbia)

9:30 AM   Panel Discussion (Chair:  Dr. Robert McCunney* MIT)

10:00 AM  COFFEE BREAK

10:30 AM  Biomarkers and Models of Radiation Exposure (Dr. Mort
          Mendelsohn*, LLNL)
10:50 AM  Biomarker Calibration for Estimating Risk (Dr. Leopold Miksche*,
          Bayer AG, Germany)
11:10 AM  Biomarkers of Pulmonary Toxicity (Dr. Alfred Bernard*, Louvain,
          Belgium)
11:30 AM  Biomarkers of Reproductive Toxicity (Dr. Don Mattison*, U. of
          Pittsburgh)

11:50 AM  Panel Discussion (Chair:  Dr. Paul Seligman*, DOE)

12:30-1:30 PM  LUNCH BREAK

SECTION:  PRACTICAL APPLICATIONS OF BIOMARKERS (Cont.)

          Session Chairman:  Dr. Eula Bingham*, U. of Cincinnati

1:30 PM   Mutant Oncoprotein Biomarkers in Chemical Carcinogenesis
          (Dr. Paul Brandt-Rauf*, Columbia)
1:50 PM   Benzene Metabolites and Benzene Chromosomal Biomarkers
          (Dr. Martyn Smith, Berkeley)
2:10 PM   Somatic Mutations (Dr. Richard Albertini*, U. of Vermont)

2:30 PM   Panel Discussion (Chair:  Dr. Dale Hattis*, Clark U.)

3:00 PM   COFFEE BREAK

3:30 PM   Cotinine as a Biomarker of Smoke Exposure (Dr. Linda Youngman*,
          Oxford, UK)
3:50 PM   Ethnic Variation and Genetic Susceptibility: G6PD (Dr. David
          Jollow*, MUSC)
4:10 PM   Breast Cancer Screening and Ethnic Variation (David Goldgar,
          IARC, France)

4:30 PM   Panel Discussion  (Chair:  Dr. Carol Redmond*, MUSC)
                           ____________________

THURSDAY MAY 8 (Physicians Memorial Auditorium-The College of Charleston)

SECTION:  ETHICAL CONSIDERATIONS

               Session Chairman:  Dr. Charles Epstein, UCSF

8:20 AM   Special Announcements
8:30 AM   Ethical Issues (Dr. Charles Epstein, UCSF)
8:50 AM   Government Uses of Genetic Information (Dr. Barry Johnson*,
          ATSDR)
9:10 AM   The Uses of Genetics in the Workplace (Dr. Eula Bingham*,
          U. of Cincinnati)
9:30 AM   Employers Perspective (Dr. Joe Cannola, Mobil Corporation)

9:50 AM   COFFEE BREAK

10:20 AM  Non-Medical Uses of Genetic Information (Mark Rothstein*,
          U. of Houston)

10:50 AM  JUDICIAL PANEL

          Biomarkers, Scientific Validity and the Judicial Process
          (The Hon. Richard A. Levie*, Deputy Presiding Judge, Civil
          Division, Superior Court  of the District of Columbia,
          The Hon. Thomas S. Ellis, III*, Judge, United State District
          Court for the District of Eastern Virginia, and Dr. Franklin
          Zweig*, President, EINSHAC)

11:30 AM  GENERAL DISCUSSION

          Panel:    Drs. Charles Epstein, Barry Johnson*, Larry Mohr*,
               Mort Mendelsohn*, Carol Henry*, Judges Richard Levie*,
               and Thomas Ellis*.

12:30          Closing remarks (Dr. Lawrence Mohr*, MUSC)

                           ____________________

MEETING ADJOURNS

* Confirmed as of 02/05/97
                                  HOTELS

May is peak tourist season in Charleston, SC and we advise you to make your
room reservations as early as possible.  To receive special rates, please
contact one of the following hotels on or before April 1, 1997, and refer to
the MUSC BIOMARKER CONFERENCE room block. Please add 12% tax to these hotel
room rates.

Francis Marion Hotel:  $109.00 per night  (803) 722-0600
(Please inform reservationist if you are a federal government employee for
a discounted room rate.  A limited number of these rooms are available on a
first call-first serve basis.)

Quality Inn:  $74.00 per night  (803) 722-3391

Hampton Inn:  $89.00 per night (803) 723-4000

Hawthorn Suites Hotel: $115.00 per night (803) 577-2644

To receive a full registration packet, please call 1-800-277-3239 or fill
out the form below and fax to Jill Yarnall at 1-803-727-6464 or mail to:

Biomarker Conference
Medical University of South Carolina
Environmental Hazards Assessment Program
156 Rutledge Avenue
Charleston, South Carolina  29403

Registration information is available on the Internet through our website
www.ehap.musc.edu

-----------------------------------------------------------------------------


From owner-genome-program@net.bio.net Tue Feb 11 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: grahamb@odder.nhgri.nih.gov (Bettie Graham)
Newsgroups: bionet.molbio.genome-program
Subject: AVAILABILITY OF FELLOWSHIPS
Date: 11 Feb 1997 20:22:01 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 67
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The National Human Genome Research Institute, formerly the National   
Center for Human Genome Research, National  Institutes of Health, is   
offering individual fellowships to highly qualified students and   
scientists who are seeking training that will enable them to engage in   
research relevant to the Human Genome Project. Training of scholars in   
examining the ethical, legal and social  Implications of human genome   
research is also encouraged, but is not available for pre-doctoral   
students.

Three types of fellowships are offered:

 1.  Postdoctoral fellowships for indivduals who have received their
doctoral degree within the last seven years.  The application receipt
dates are  April 5, August 5 and December 5.

 2.  Senior postdoctoral fellowships for individuals who received their   
    

doctoral degree  more than seven years ago.  The application receipt
dates are April 5, August 5 and December 5.

 3.  Pre-doctoral Minority fellowships for underrepresented minority
graduate students to pursue a doctoral degree.  The application receipt   
    

dates are May 1 and November 15.

Fellowship support is provided through the National Research Service
Award.  Only U.S. citizens or permanent residents of the United States   
are eligible to apply.

For additional information about fellowship opportunities available
through the NCHGR, please visit our home page at:
 http://www.nhgri.nih.gov.  You may also contact the following staff:

Individual and Senior Postdoctoral Fellowships and Minority Pre-Doctoral   
Fellowships in Genomic Analysis and Technology:

Bettie J. Graham, Ph.D..
TEL:  (301) 496-7531
e-mail:  bettie_graham@nih.gov


Individual and Senior Postdoctoral Fellowships in ELSI Topics:
Eric M. Meslin, Ph.D..
TEL:  (301) 402-4997
e-mail:  eric_meslin@nih.gov

For information about PHS Grant Policy, applicants may contact:

Ms. Jean Cahil
TEL:  (301) 402-0733
e-mail:  jean_cahill@nih.gov










From owner-genome-program@net.bio.net Mon Feb 17 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: NEWSMGR@selu.edu
Newsgroups: bionet.molbio.genome-program
Subject: Impact on human genetic diseases
Date: 18 Feb 1997 11:50:42 -0800
Organization: Southeastern Louisiana University
Lines: 40
Sender: daemon@net.bio.net
Approved: k76@ornl.gov
Distribution: world
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NNTP-Posting-Host: net.bio.net

Relay-Version: VMS News - V6.1 24/02/92 VAX/VMS V6.2; site altair.selu.edu
Path:
altair.selu.edu!te6000.otc.lsu.edu!news.cis.uab.edu!gatech!news.sprintlink.n
et!
 news-peer.sprintlink.net!howland.erols.net!newsxfer3.itd.umich.edu!
 portc01.blue.aol.com!wcnews01.ops.aol.com!newsjunkie.ans.net!

newsfeeds.ans.net!lantana.singnet.com.sg!peony.singnet.com.sg!nuscc.nus.sg!t
ehjinsi
Newsgroups: bionet.molbio.genome-program
Subject: Impact on human genetic diseases
Message-ID: <5e13u5$h2k@nuscc.nus.sg>
From: tehjinsi@iscs.nus.sg (Jin Sim)
Date: 14 Feb 1997 07:23:49 GMT
Organization: National University of Singapore
NNTP-Posting-Host: tehjinsi@decunx.iscs.nus.sg
X-Newsreader: TIN [version 1.2 PL2]
Lines: 19

Hi,

Currently, I'm doing a project on:
 
'The impact of the Human Genome Project on human genetic diseases and
their diagnosis, prevention and therapy.'

I'd appreciate it if I could hear your opinions on this.

Thanks :)

--
Jeanie Teh                                             	  		
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-==-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=
Most people are other people, their thoughts are someone else's opinions,
their lives a mimicry, their passions a quotation.
							 - Oscar Wilde -
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-==-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=




From owner-genome-program@net.bio.net Tue Feb 18 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: bkq@ornl.gov (Betty K Mansfield)
Newsgroups: bionet.molbio.genome-program
Subject: DOE Microbial Genome Program Notice 97-10 -
Date: 19 Feb 1997 09:04:32 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 9
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Approved: k76@ornl.gov
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NNTP-Posting-Host: net.bio.net

A call for proposals on an HGP spin off program  is located at:
     
     The Program Notice 97-10 on the Department of Energy Microbial Genome
Program was published today, February 19, 1997, in the Federal Register.
It is also available at the ER Grants and Contracts Web Site:
     
              http://www.er.doe.gov/production/grants/grants.html
     
     

From owner-genome-program@net.bio.net Tue Feb 18 22:00:00 1997
Path: biosci!biosci!not-for-mail
From: BIOSCI Administrator <biohelp@net.bio.net>
Newsgroups: bionet.molbio.genome-program
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 19 Feb 1997 09:04:33 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 241
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NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net



