From owner-evolution@net.bio.net Sun Dec 01 22:00:00 1996
Path: biosci!agresearch.cri.nz!Farr
From: Farr@agresearch.cri.nz ("Farr, Tracy")
Newsgroups: bionet.molbio.evolution
Subject: suggestions for restrctn frag data treat
Date: 1 Dec 1996 18:07:19 -0800
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Can anyone suggest methods and software appropriate for analysis that   
might help us classify"supertypes" obtained from restriction enzyme   
analysis of Mycobacterium bovis (i.e. bacterial) DNA using three separate   
enzymes?

We are currently using Whole Band Analysis software from Bio Image on a   
Sun workstation to match samples on scanned gels to reference type   
patterns for each of three restriction enzymes. Types differ in the   
position of bands (from 22 to around 30 bands depending on enzyme), as   
well as their intensity and width, in some cases. So, bands are not just   
present or absent (1/0), but can also be higher, lower, narrower,   
broader, or of higher or lower intensity compared to any other particular   
reference type within the enzyme set of patterns. The Bio Image software   
can report matching results in dendrogram form (minimum, UPGMA, maximum,   
neighbour joining methods), and I am starting to investigate using this   
tool to generate a  classification, a measure of relatedness, for the   
types for each enzyme.

My question is this, though: what methodology might we use to go one step   
further, to infer/generate measures of similarity or clustering or   
relatedness between the "supertypes" we obtain for each sample by   
combining the types from each of the three enzymes?

We have recorded over 160 "supertypes", comprising the 70, 70 and 45   
different types recorded, respectively, for each of the three enzymes.   
Some of these supertypes differ from others by just one band difference   
in one of the three enzymes, while others show numerous pattern   
differences for all three enzymes.

While a novice in the field of molecular systematics, my preliminary   
reading has made me aware of the inherent problems in dealing with this   
sort of restriction fragment data as opposed to restriction site data.   
Still, we would like to generate some measure of relatedness for these   
supertypes.

I realise that some simplification of the data may be in order (reducing   
it to 1/0 for each possible band position, for instance).

Thanks in advance for any assistance or advice.


 ----------------------------------------------------------------------
Tracy Farr

AgResearch,
Wallaceville A.R.C.,
Upper Hutt,  Phone 64-04-528.6089
New Zealand  Fax 64-04-528.1380
 ----------------------------------------------------------------------
Disclaimer: The above is a personal opinion and does not
reflect the official view of AgResearch Ltd.
 ----------------------------------------------------------------------
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From owner-evolution@net.bio.net Sun Dec 01 22:00:00 1996
Path: biosci!ihnp4.ucsd.edu!swrinde!cs.utexas.edu!howland.erols.net!news-peer.gsl.net!news.gsl.net!ix.netcom.com!tor-nn1.netcom.ca!news
From: Allan <bod@netcom.ca>
Newsgroups: bionet.molbio.evolution
Subject: Help needed for biology project!!!
Date: Sun, 01 Dec 1996 19:35:49 -0500
Organization: Netcom Canada
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Hello! Would anyone who has a career in biology be interested
in letting me do an e-mail interview with them for my OAC (if you don't
live in Ontario Canada you will know OAC as grade 13) biology project.
If anyone is interested PLEASE e-mail me. My name is Allan Graham, and
my e-mail address is bod@netcom.ca .

From owner-evolution@net.bio.net Mon Dec 02 22:00:00 1996
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!news.sprintlink.net!news-peer.sprintlink.net!news.sprintlink.net!news-hub.sprintlink.net!news.sprintlink.net!news-stk-11.sprintlink.net!news.dx.net!portal.dx.net!not-for-mail
From: Xtra_Cash@your.home.com (MoMoney)
Newsgroups: bionet.molbio.bio-matrix,bionet.molbio.embldatabank,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.genbank
Subject: Earn extra cash for the holidays working from home.
Date: 2 Dec 1996 20:42:35 -0500
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       Homeworkers Urgently Needed!
 
   Earn weekly paychecks from the comfort
              of your home.
  FREE details. Send long, self-addressed,
          stamped envelope to:
 
          S.P.E.L.,  Dept IN-2
            PO Box 211-111
          Royal Palm Bch, FL
                   33421-1111
 


From owner-evolution@net.bio.net Mon Dec 02 22:00:00 1996
Path: biosci!daresbury!not-for-mail
From: martar@porthos.bio.ub.es (Marta Riutort)
Newsgroups: bionet.molbio.evolution
Subject: re: ribosomal RNAs
Date: 3 Dec 1996 11:36:13 -0000
Lines: 23
Sender: lpddist@mserv1.dl.ac.uk
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In response to the existence of different sequences for the rDNAs in some
species, we have also found a case, within the Platyhelminthes, in which
various species of a same family have two different types of 18S rDNA
sequences. These two types diverge by around an 8% in their sequence, and
although both seem to be functional (because the secondary structure is
conserved), we have only found one in the form of RNA. (Mol. Biol. Evol.
13(6):824-832). Of course the existence of these two types can affect the
use of this molecule as a phylogenetic tool, if one have (inadvertedly)
sequences of different types for the different species to compare, one will
get a wrong phylogeny.


************************************************
  Marta Riutort
  Dpt. de Genetica
  Fac. de Bilogia
  Av. Diagonal, 645
  08071 Barcelona (Spain)

  Tel: 34-3 402 15 00
  Fax: 34-3 411 09 69
  e-mail: martar@porthos.bio.ub.es


From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
Path: biosci!ed.ac.uk!Mark.Dorris
From: Mark.Dorris@ed.ac.uk (Mark Dorris)
Newsgroups: bionet.molbio.evolution
Subject: Re: DCSE-Nexus-Treecon-help!
Date: 4 Dec 1996 09:12:54 -0800
Organization: Nematode Genetics, ICAPB, University of Edinburgh
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Bart Nelissen wrote:

> The software package TREECON for Windows includes the ReadSeq module,
> with the extra possibility to convert from and to the TREECON format,
> and the LINUX/UNIX version of DCSE (tkDCSE) contains the program
> tkCONVERS which converts from the DCSE alignment format to the TREECON
> format and also includes the ReadSeq module.

I run the UNIX version DCSE and am aware of the tkCONVERS program. My 
original enquiry was more concerned with conversion to and from Nexus 
format from the formats used by DCSE and Treecon. A perl program may 
do the trick. Does anyone know if one exists?

Thanks

Mark Dorris
________________________________________________
Mark Dorris   email Mark.Dorris@ed.ac.uk
Institute of Cell, Animal and Population Biology
Ashworth Laboratories, King's Buildings
University of Edinburgh,  West Mains Road
EDINBURGH  EH9 3JT,  United Kingdom
phone: (+44) 131 650 6760  Fax :...650 5450

From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
Newsgroups: bionet.molbio.evolution
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!news-peer.gsl.net!news.gsl.net!news-dc.gsl.net!news.gsl.net!news.belnet.be!news.vub.ac.be!hnets.uia.ac.be!news
From: Bart Nelissen <nelissen@uia.ua.ac.be>
Subject: Re: DCSE-Nexus-Treecon-help!
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B.L.Cohen wrote:

> Unlikely, because the Antwerp group have been very bad about/ignorant of
> interchange formats.

	Please do not make statements that are completely incorrect. Both
TREECON and DCSE can convert between different file formats. So it is
you who is ignorant about the possibilities of TREECON and DCSE.
	The software package TREECON for Windows includes the ReadSeq module,
with the extra possibility to convert from and to the TREECON format,
and the LINUX/UNIX version of DCSE (tkDCSE) contains the program
tkCONVERS which converts from the DCSE alignment format to the TREECON
format and also includes the ReadSeq module. More information can be
found at the following URL's

DCSE: http://www-rrna.uia.ac.be/~peter/dcse/index.html
TREECON: http://bioc-www.uia.ac.be/u/yvdp/treecon.html

Best wishes,

		Bart Nelissen
-- 
Dr. Bart Nelissen		| Tel:	+ 32 3 820 23 16
Department of Biochemistry	| Fax:	+ 32 3 820 22 48
University of Antwerp (UIA)	| E-mail: nelissen@uia.ua.ac.be
Universiteitsplein 1		| WWW: http://www.uia.ac.be/u/nelissen
B-2610 Antwerp (Wilrijk)	| 
Belgium				|

From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
Path: biosci!ihnp4.ucsd.edu!munnari.OZ.AU!news.ecn.uoknor.edu!feed1.news.erols.com!howland.erols.net!math.ohio-state.edu!jussieu.fr!infobiogen.fr!lovelace.infobiogen.fr!coulier
From: Francois Coulier <coulier@infobiogen.fr>
Newsgroups: bionet.molbio.evolution
Subject: Re: ANTIBIOTICS PROMOTE CANCER
Date: Wed, 4 Dec 1996 08:19:30 +0100
Organization: "GIS INFOBIOGEN, 7 rue Guy Moquet BP8, 94801 VILLEJUIF, France"
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To: Mark Peters <gquest@nol.net>
In-Reply-To: <32A4FEB5.3455@nol.net>

Are you sure you choosed the right newsgroup?

*  *  *  *  *  *  *  *  *  *  *  *  *
Francois Coulier
INSERM Unite 119
27 bd Lei Roure
13009 Marseille
France

tel 33 (0) 4 91 75 84 11
fax 33 (0) 4 91 26 03 64)
email: coulier@infobiogen.fr
*  *  *  *  *  *  *  *  *  *  *  *  *



From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
Path: biosci!ihnp4.ucsd.edu!swrinde!cs.utexas.edu!howland.erols.net!newsfeed.internetmci.com!nol.net!not-for-mail
From: Mark Peters <gquest@nol.net>
Newsgroups: bionet.molbio.evolution
Subject: ANTIBIOTICS PROMOTE CANCER
Date: Tue, 03 Dec 1996 20:31:49 -0800
Organization: GENIUS QUEST
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Who cares? Anyone?  

Antibiotics kill the bad germs. (The ones that don't become antibiotic
resitant).  Antibiotics also kill the good germs that help prevent the
spread of bad germs. (loss of the good germs makes open season for
antibiotic resistant bad germs) "Antibiotics" that do not kill yeast
(open the season) and promote their growth.  The yeast C. albicans can
catalyze nitrosamine (a carcinogen) that causes cancer.  

Wide spread usage of antibiotics gained momentum in the 1950's.  The
incidence of cancer has been rising yearly since then.

Who cares anyway?

More cancer, more money for doctors, more money for research, more new
antibiotics.

The FDA approved them, doctors fear loss of customers($money) if they
don't prescribe them and the patients (victoms)feel cheeted if they
don't get them.  Patients  THINK antibiotics cure everything and then
come to rely on the wolves (capitalism) to guard their health while the
system herds them like sensless sheep into human petrie dishes to test
their latest and greatest kill everyting antibiotic.

It's not really anybody's fault in perticular(we didn't know yeast cause
cacner in 1950) so lets just pretend we didn't even read this message. 
Forget it completely so you won't feel responsible when you or your
loved one is the next one in your family who draws the short straw.
(Murder by cancer is not illegal.)  Infact, it it isn't even recognized
as a "STING", THE.  (great movie) 

OR.  Challenge me, you fearless sole, (hope you have some legal teeth in
your bark or you will be just waisting my time) to back my statements. 
At least act like you care even though you can't do anything about this
world wide medical macicality.  The Presidents have ignored me, the
television stations are silent, the FBI has no jurisdiction, the doctors
are to far along out of medical school to read technical relatinships
from mainstreem medical material.  


WHEN THE LINE OF PRECEPTIN BETWEEN FACT AND FICTION DISAPPEARES, EVIL
HAS WON.

From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
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From: pingouin@crystal.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.molbio.evolution
Subject: Re: ANTIBIOTICS PROMOTE CANCER
Followup-To: alt.conspiracy
Date: 4 Dec 1996 08:43:06 GMT
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In article <32A4FEB5.3455@nol.net>,
	Mark Peters <gquest@nol.net> writes:
>Who cares? Anyone?  
>
>Antibiotics kill the bad germs. (The ones that don't become antibiotic
>resitant).  Antibiotics also kill the good germs that help prevent the
>spread of bad germs. (loss of the good germs makes open season for
>antibiotic resistant bad germs) "Antibiotics" that do not kill yeast
>(open the season) and promote their growth.  The yeast C. albicans can
>catalyze nitrosamine (a carcinogen) that causes cancer.  

	It is not the right group, but I have to answer. AFAIK, 
C albicans is a pathogen yeast, present in minority in mocous
membrane. If the selection by antibiotics make it the majority,
then it provocs a disease called candidose.

	So don't worry, each desequilibrium in epiderm or mucus
microorganic flora is visible.

				If this helps,
						Francois.

P.S.: Follow-Up to alt.conspiracy
-- 
Francois Jeanmougin
Service de bioinformatique / bioinformatics service
IGBMC BP 163 67404 Illkirch France
tel :(France) 03 88 65 32 71 / (international) (+33) 3 88 65 32 71
e-mail : jeanmougin@igbmc.u-strasbg.fr
"C'est pas parcequ'on monte au banc, qu'il faut descendre a jeun." (Thiefaine)


From owner-evolution@net.bio.net Tue Dec 03 22:00:00 1996
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From: Jeffrey Allan Simon <jbsimon@ix.netcom.com>
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: Wed, 04 Dec 1996 23:14:44 GMT
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In article <m0vPkk2-0000JgC@uctmail.uct.ac.za>,
	ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki") wrote:

>> To:            mol-evol@net.bio.net
>> From:          Jeff Bush <jbush@afit.af.mil>
>> Subject:       Re: Anyone Seen Evolution?
>> Date:          Mon, 18 Nov 1996 17:02:34 -0500
>
>Jeff trawled...
>
>>... My question was pointing at *observing* a 
>> benifitial mutation in the genetic code.
>
>sp: beneficial B-)
>
>And yes, if you take BK virus (a polyomavirus) out of the urine of 
>immunosuppressed patients, and cycle it in tissue culture (in which 
>it initially refuses to grow), checking it frequently by PCR and 
>sequencing, you will find that tissue culture-adapted mutants arise, 
>all of which independently have rearranged their "control regions".  
>In other words, the viruses mutate at a hot-spot, and the ones which 
>are viable come through.  VERY beneficial, for the virus.  And can be 
>found in the lit in J Virol by Rubinstein and Harley some years ago.
>
>So sorry, Jeff, one can and does observe beneficial mutations.  
>Another is the one(s) which allow Mycobacterium tuberculosis (causes 
>TB) to become resistant to certain antibiotics - and yes, one can 
>prove it is mutation and not pre-existing sequence by PCRing the 
>gene(s) in question before and after seeing the resistance arise in 
>culture, making a library, and looking for it/them.
>
>Back to the Book, Jeff....
>
>
>
>                     Ed Rybicki, PhD  
>      Dept Microbiology     |   ed@molbiol.uct.ac.za   
>   University of Cape Town  | rybicki@uctvms.uct.ac.za
>   Private Bag, Rondebosch  |  phone: x27-21-650-3265
>      7700, South Africa    |   fax: x27-21-689 7573
>    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
>                                        
>    "Out here on the perimeter, there are no stars..."

Fascinating Ed, but tell me, what is the name of this new species that has "evolved?"  These
appear to be examples of microevolution.  These examples cannot be used to extrapolate from E
coli to man.  An organism adapting to its environment is a great example of natural selection,
but natural selection is just as compatible with creation.  With the billions of years of
evolution, there should be better examples of evolution, both in the present and in the past. 
Back to your hypothesizing Ed.....  

From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
Path: biosci!MOLBIOL.UCT.AC.ZA!ed
From: ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki")
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 04:40:24 -0800
Organization: Dept Microbiology, UCT
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> To:            mol-evol@net.bio.net
> From:          un691cs@genius.embnet.dkfz-heidelberg.de (slavemaster)
> Subject:       Re: Anyone Seen Evolution?

> Problem is the definition of what a species is ! as I recall correctly from
> biology 107: aspecies is defined as an organism that can produce fertile 
> offspring if mated with an organism of the same species.
> With E.coli (a-sexual multiplication) or a virus, the definition of a species is almost
> impossible, 

...but has been done: taxonomy committees for both groups of 
organisms have defined species for both, so the mating concept falls 
away.

                     Ed Rybicki, PhD  
      Dept Microbiology     |   ed@molbiol.uct.ac.za   
   University of Cape Town  | rybicki@uctvms.uct.ac.za
   Private Bag, Rondebosch  |  phone: x27-21-650-3265
      7700, South Africa    |   fax: x27-21-689 7573
    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
                                        
    "Out here on the perimeter, there are no stars..."

From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
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From: un691cs@genius.embnet.dkfz-heidelberg.de (slavemaster)
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 10:04:55 GMT
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In article <58505p$oi7@sjx-ixn10.ix.netcom.com>, jbsimon@ix.netcom.com says...

>Fascinating Ed, but tell me, what is the name of this new species that has "evolved?"  These
>appear to be examples of microevolution.  These examples cannot be used to extrapolate from E
>coli to man.  An organism adapting to its environment is a great example of natural selection,
>but natural selection is just as compatible with creation.  With the billions of years of
>evolution, there should be better examples of evolution, both in the present and in the past. 
>Back to your hypothesizing Ed.....  

Problem is the definition of what a species is ! as I recall correctly from
biology 107: aspecies is defined as an organism that can produce fertile 
offspring if mated with an organism of the same species.
With E.coli (a-sexual multiplication) or a virus, the definition of a species is almost
impossible, and thus talking about observing actual evolution taking place may
be difficult. Even though IMHO opinion micro-evolution (sounds like a creationist 
invention, such an un-word) does point towards evolution taking place.

We humans may simply live too short to observe the actual evolution taking place ?
But certainly there must be numerous breeds of cattle or other animals that have 
been bred to such an extend, that they can't be mated with their forefathers anymore ?

Anybody seen the production of a novel species of sheep or anything ?

 
Clemens


From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
Path: biosci!MOLBIOL.UCT.AC.ZA!ed
From: ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki")
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 00:45:12 -0800
Organization: Dept Microbiology, UCT
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NNTP-Posting-Host: net.bio.net

> From:          Jeffrey Allan Simon <jbsimon@ix.netcom.com>
> Subject:       Re: Anyone Seen Evolution?
I wrote:
> >And yes, if you take BK virus (a polyomavirus) out of the urine of 
> >immunosuppressed patients, and cycle it in tissue culture (in which 
> >it initially refuses to grow), checking it frequently by PCR and 
> >sequencing, you will find that tissue culture-adapted mutants arise, 
> >all of which independently have rearranged their "control regions".  
> >In other words, the viruses mutate at a hot-spot, and the ones which 
> >are viable come through.  VERY beneficial, for the virus.  And can be 
> >found in the lit in J Virol by Rubinstein and Harley some years ago.
...
> >Back to the Book, Jeff....

Jeff wrote:
> Fascinating Ed, but tell me, what is the name of this new species that has "evolved?"  These
> appear to be examples of microevolution.  These examples cannot be used to extrapolate from E
> coli to man.  An organism adapting to its environment is a great example of natural selection,
> but natural selection is just as compatible with creation.  With the billions of years of
> evolution, there should be better examples of evolution, both in the present and in the past. 
> Back to your hypothesizing Ed.....  

You asked for an example one could see/watch: I gave you one.  Now 
you ask for a new species...OK, recombinant geminiviruses, with 
hybrid genomes, that infect wider / different host ranges of plants 
(to be found all over S and N America presently) - and evidence that 
an ancient recombination gave rise to an entire GENUS of 
Geminiviridae (hybrid genome betweem Subgroup I and III 
geminiviruses), with new properties / host range / etc.

Buth that won't satisfy you either, will it?  

                     Ed Rybicki, PhD  
      Dept Microbiology     |   ed@molbiol.uct.ac.za   
   University of Cape Town  | rybicki@uctvms.uct.ac.za
   Private Bag, Rondebosch  |  phone: x27-21-650-3265
      7700, South Africa    |   fax: x27-21-689 7573
    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
                                        
    "Out here on the perimeter, there are no stars..."

From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
Newsgroups: bionet.molbio.evolution
Path: biosci!ihnp4.ucsd.edu!swrinde!news.sgi.com!news.sprintlink.net!news-peer.sprintlink.net!uunet!in1.uu.net!192.35.48.11!hearst.acc.Virginia.EDU!murdoch!avery.med.Virginia.EDU!cbw2c
From: "C.B. Wiegand" <cbw2c@avery.med.Virginia.EDU>
Subject: Re: ANTIBIOTICS PROMOTE CANCER
In-Reply-To: <32A4FEB5.3455@nol.net>
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On Tue, 3 Dec 1996, Mark Peters wrote:

> Who cares? Anyone?  
> 
> Antibiotics kill the bad germs. (The ones that don't become antibiotic
> resitant).  Antibiotics also kill the good germs that help prevent the
> spread of bad germs. (loss of the good germs makes open season for
> antibiotic resistant bad germs) "Antibiotics" that do not kill yeast
> (open the season) and promote their growth.  The yeast C. albicans can
> catalyze nitrosamine (a carcinogen) that causes cancer.  

[excess conspiracy rant deleted]

First, ain't this a little off-topic for this newsgroup?

Nitrosamine IS a mutagen and potential carcinogen, along with
about 10000 other sustances we are exposed to on a daily basis.
It is formed by Candida albicans BUT it is also formed from nitrites via
a reaction with gastric enzymes. So you'd better include the
processed-food folks in your circle of conspirators--hot dog consumption
is even more common than yeast infections.    :)

BTW, the push these days in medical education is to use antibiotics very
sparingly.  Gone are the days when docs would throw penicillin at every
cough, sneeze, and bellyache.  If you think nitrosamines are scary, try
MRSA and VRE!

Ciao,

Chris

--
Christopher B. Wiegand		
UVa School of Medicine `99

But nowadays men cannot love seven night but they must have all
their desires: that love may not endure by reason; for where they
be soon accorded and hasty, heat soon it cooleth.  Right so fareth
love nowadays, soon hot soon cold: this is no stability.

	--from _Le Morte D'Arthur_, Book XVIII, Chapter 25
	  Sir Thomas Malory, 1485



From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
Path: biosci!daresbury!not-for-mail
From: James McInerney <j.mcinerney@nhm.ac.uk>
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 10:02:47 -0000
Organization: The Natural History Museum
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Reply-To: j.mcinerney@nhm.ac.uk
MIME-Version: 1.0
Original-To: Molecular Evolution Group <mol-evol@dl.ac.uk>

Ed,

Don't do it, man.  We have debated what to do about creationists and the
accepted wisdom is to ignore these posts.  The place for that kind of
discussion is on talk.origins or somewhere like that.  This is an
entirely different newsgroup and this discussion is off limits.

James.

--
James O. McInerney, The Natural History Museum, Cromwell Road,
London SW7 5BD, UK.

From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
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From: un691cs@genius.embnet.dkfz-heidelberg.de (slavemaster)
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 16:58:29 GMT
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In article <m0vVd68-0004ZcC@uctmail2.uct.ac.za>, ed@MOLBIOL.UCT.AC.ZA says...
>
>> To:            mol-evol@net.bio.net
>> From:          un691cs@genius.embnet.dkfz-heidelberg.de (slavemaster)
>> Subject:       Re: Anyone Seen Evolution?
>
>> Problem is the definition of what a species is ! as I recall correctly from
>> biology 107: aspecies is defined as an organism that can produce fertile 
>> offspring if mated with an organism of the same species.
>> With E.coli (a-sexual multiplication) or a virus, the definition of a species is almost
>> impossible, 
>
>...but has been done: taxonomy committees for both groups of 
>organisms have defined species for both, so the mating concept falls 
>away.

Hm interesting. I'm not familiar with this: how
is a species defined nowadays ? 
(aslo: I remember a dixussion once on the telly 
between creationists and normal people and in the end
the creationist had to admit that new species are being
formed. But they THEN went ahead and stated that this is still
no proof for evolution, because its unimaginable that
a complete new genus or even taxa are being formed !

But anyway: do you have examples of higher organsims 
where evolution is more or less obvious ?

clemens


From owner-evolution@net.bio.net Wed Dec 04 22:00:00 1996
Path: biosci!BELOIT.EDU!jungck
From: jungck@BELOIT.EDU (John R. Jungck)
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 5 Dec 1996 12:44:18 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 48
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Message-ID: <v01540b02aecc9e5cfff2@[144.89.51.91]>
NNTP-Posting-Host: net.bio.net

Dear unnamed participant,

I have to say that this discussion seems enormously misplaced, but look at
plants: allopolyploidy in the Brassica family is an excellent example.

John

 >In article <m0vVd68-0004ZcC@uctmail2.uct.ac.za>, ed@MOLBIOL.UCT.AC.ZA says...
>>
>>> To:            mol-evol@net.bio.net
>>> From:          un691cs@genius.embnet.dkfz-heidelberg.de (slavemaster)
>>> Subject:       Re: Anyone Seen Evolution?
>>
>>> Problem is the definition of what a species is ! as I recall correctly from
>>> biology 107: aspecies is defined as an organism that can produce fertile
>>> offspring if mated with an organism of the same species.
>>> With E.coli (a-sexual multiplication) or a virus, the definition of a
>>>species is almost
>>> impossible,
>>
>>...but has been done: taxonomy committees for both groups of
>>organisms have defined species for both, so the mating concept falls
>>away.
>
>Hm interesting. I'm not familiar with this: how
>is a species defined nowadays ?
>(aslo: I remember a dixussion once on the telly
>between creationists and normal people and in the end
>the creationist had to admit that new species are being
>formed. But they THEN went ahead and stated that this is still
>no proof for evolution, because its unimaginable that
>a complete new genus or even taxa are being formed !
>
>But anyway: do you have examples of higher organsims
>where evolution is more or less obvious ?
>
>clemens

John R. Jungck
Biology
Beloit College
700 College Street
Beloit, WI 53511

Web site for the BioQUEST Curriculum Consortium:
        http://www.beloit.edu/~bquest



From owner-evolution@net.bio.net Thu Dec 05 22:00:00 1996
Path: biosci!bcm.tmc.edu!cs.utexas.edu!swrinde!www.nntp.primenet.com!nntp.primenet.com!su-news-hub1.bbnplanet.com!news.bbnplanet.com!cam-news-hub1.bbnplanet.com!news.idt.net!cdc2.cdc.net!news.stealth.net!newsfeed.uk.ibm.net!news-m01.ny.us.ibm.net!news-s01.ny.us.ibm.net!not-for-mail
From: "Antonio Machado" <a.machado@ibm.net>
Newsgroups: bionet.molbio.evolution
Subject: Soft introduction to molbio concepts. HELP.
Date: 6 Dec 1996 19:24:00 GMT
Organization: IBCER
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Hallo. I am interested in understanding the basics of molbio assessment of
evolutionary changes (oriented to phylogeny). I work in classic phylogeny &
cladistics via external morphology. Is there a "userfriendly" article or
book to start with?
Thanks & gracias
Antonio

From owner-evolution@net.bio.net Thu Dec 05 22:00:00 1996
Path: biosci!biosci!not-for-mail
From: "E. Kolker" <egn@u.washington.edu>
Newsgroups: bionet.general,bionet.info-theory,bionet.molbio.proteins,sci.med.pharmacy,bionet.molbio.embldatabank,bionet.population-bio,bionet.molbio.evolution,sci.bio.systematics,bionet.software
Subject: New deadline & Web site
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Xref: biosci bionet.general:24391 bionet.info-theory:4414 bionet.molbio.proteins:9500 sci.med.pharmacy:37773 bionet.molbio.embldatabank:729 bionet.population-bio:2126 bionet.molbio.evolution:5408 sci.bio.systematics:1449 bionet.software:17299



                        ANNOUNCEMENT AND CALL FOR PAPERS

                        Computational Biology Session:
                         "Computing in the Genome Era"
                            March 31 - April 1, 1997

         Eleventh International Conference on Mathematical and Computer
                       Modelling and Scientific Computing

                            March 31 - April 3, 1997
                    Georgetown University Conference Center
                              Washington, DC, USA 


	The Eleventh International Conference on Mathematical and Computer
Modelling and Scientific Computing is scheduled to take place March 31 -
April 3, 1997 at the Georgetown University Conference Center, Washington,
DC, U.S.A. The objective of the Computational Biology Session "Computing
in the Genome Era" (March 31 - April 1, 1997) is to discuss the current
state of computational biology, its approaches, methods, general problems,
achievements, and future developments with emphasis on sequence research
and analysis for the Genome Projects. 

SPEAKERS of the session include: 

        S. Altschul     (Natl Center for Biotechnology Iinformation, Bethesda),
        A. Bairoch      (Geneva University, Switzerland),
        T. Clark        (Millenium Pharmaceuticals, Cambridge), 
        W. Gish         (Washington University, St. Louis), 
        T. Gojobori     (Natl Institute of Genetics, Mishima, Japan),
        P. Green        (University of Washington, Seattle), 
        S. Henikoff     (Fred Hutchinson Cancer Research Center, Seattle), 
        L. Hood         (University of Washington, Seattle), 
        A. Kerlavage    (Institute for Genomic Research, Rockville),
        E. Koonin       (Natl Center for Biotechnology Iinformation, Bethesda),
        O. Ritter       (German Cancer Research Center, Heidelberg, Germany),
        D. Searls       (SmithKline Beecham Pharmaceuticals, King of Prussia), 
        E. Shpaer       (Perkin-Elmer Applied Biosystems, Foster City),
        E. Trifonov     (Weizmann Institute of Science, Israel).

STEERING COMMITTEE:

S. Altschul, A. Bairoch, W. Gish, P. Green, S. Henikoff, E. Koonin, E. Trifonov
 
        Papers (Abstracts) are invited on all relevant aspects of
computational biology for presentation at the session (a new deadline is
DECEMBER 23, 1996), to be selected on competitive basis by the steering
committee (notification of acceptance is JANUARY 4, 1997). One-page
abstracts should clearly describe the work and its conclusions. Full
length manuscripts (limited to six pages) of papers presented at the
conference will be published in the Conference Proceedings, in a special
issue of the journal MATHEMATICAL MODELLING AND SCIENTIFIC COMPUTING, Vol. 
8, 1997 (ISSN 1067-0688). The manuscripts for the special issue are due
JUNE 15, 1997. The special issue of the journal will be published by
SEPTEMBER 1997. ALL participants shall pay the registration fee. 

        Abstracts (ONE PAGE, about 200 words, PLAIN JUSTIFIED TEXT) may be
submitted in hard copy or via fax or by e-mail (PREFERRED) under subject
"Abstract". The abstracts must be formatted to fit on 8-1/2 x 11 inch
(approximately 21.5 cm x 28 cm or European Standard A-4 size) paper, typed
in single space. The title must be capitalized and centered followed by
the author's name(s), institution, and full address, including fax and
e-mail.  Send two copies (ONE copy if sent by fax or e-mail) of the
abstract to the session organizer before DECEMBER 23, 1996: 

Eugene Kolker                                         
Dept of Molecular Biotechnology and Genome Center     
Box 357730, University of Washington                  
Seattle, WA 98195-7730, USA           

Fax: +1-206-685-7301
E-mail: egn@u.washington.edu


The Computational Biology Session is proudly sponsored by
        SMITHKLINE BEECHAM and MILLENIUM.


You can find additional info on our Web site:
http://www.genome.washington.edu/~eugene/meeting.html







From owner-evolution@net.bio.net Thu Dec 05 22:00:00 1996
Path: biosci!BELOIT.EDU!jungck
From: jungck@BELOIT.EDU (John R. Jungck)
Newsgroups: bionet.molbio.evolution
Subject: Re: Soft introduction to molbio concepts. HELP.
Date: 6 Dec 1996 13:46:39 -0800
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 25
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <v01540b03aecdfd2fbdb4@[144.89.51.91]>
NNTP-Posting-Host: net.bio.net

The Maddison brothers' MacClade manual (Sinauer Publishers) has an
excellent introduction to phylogenetic systematics (including molecular
characters) which is exceptional readable.

Enjoy,

John

>Hallo. I am interested in understanding the basics of molbio assessment of
>evolutionary changes (oriented to phylogeny). I work in classic phylogeny &
>cladistics via external morphology. Is there a "userfriendly" article or
>book to start with?
>Thanks & gracias
>Antonio

John R. Jungck
Biology
Beloit College
700 College Street
Beloit, WI 53511

Web site for the BioQUEST Curriculum Consortium:
        http://www.beloit.edu/~bquest



From owner-evolution@net.bio.net Fri Dec 06 22:00:00 1996
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From: Douglas Easton <dpeaston@wzrd.com>
Newsgroups: bionet.molbio.evolution
Subject: Genetics Position
Date: Sat, 07 Dec 1996 11:19:52 -0500
Organization: State University College at Buffalo (Biology)
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GENETICIST
                                    
                    STATE UNIVERSITY(SUNY)COLLEGE AT BUFFALO


Applications are invited for a tenure-track ASSISTANT PROFESSOR
to begin September 1997.  We are seeking a colleague who is
enthusiastic about teaching undergraduates.  Teaching
responsibilities will include Genetics, Introductory Biology for
non-majors, and either Botany or Cell Biology.  The successful
candidate will be expected to develop an active research program
involving undergraduate and master's students.  Applicants must
have a Ph.D., and postdoctoral teaching and research experience
is preferred but not required.


The State University College at Buffalo (Buffalo State College)
is the largest arts and science college in the SUNY system with
an enrollment of 13,000 students (including 2000 in graduate
programs).  The campus is located in a residential district in
the city of Buffalo.  The Department of Biology enrolls about 250
undergraduate and about 30 graduate students in MA and MSEd
programs.  Of our 16 faculty, one-half have received their
doctorates within the last 13 years.  We maintain greenhouse
facilities, environmental chambers and research laboratories. 
The College's newly renovated Aquatic Research Laboratory
provides laboratories and research vessels to faculty and
students.


Applicants should send a curriculum vitae with a thoughtful
statement of teaching philosophy, research goals and three
letters of recommendation by January 20, 1997 to:


Dr. Randal Snyder, Chair of Search Committee, Department of
Biology, Buffalo State College, 1300 Elmwood Avenue, Buffalo, NY
14222.  Email: SNYDERRJ@SNYBUFAA.CS.SNYBUF.EDU  Telephone: 716-
878-4314.   We especially encourage applications from women and
minorities.

From owner-evolution@net.bio.net Sun Dec 08 22:00:00 1996
Path: biosci!news.alaska.edu!ftjrd
From: ftjrd@aurora.alaska.edu (John Demboski)
Newsgroups: bionet.molbio.evolution
Subject: 2 job announcements -U Alaska Fairbanks
Date: Sun, 08 Dec 1996 16:20:27 -0800
Organization: University of Alaska Computer Network
Lines: 108
Message-ID: <ftjrd-ya023180000812961620270001@news.alaska.edu>
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X-Newsreader: Yet Another NewsWatcher 2.3.1

The University of Alaska Fairbanks is seeking qualified applicants
for two tenure-track Assistant Professor positions: Cellular/Molecular
Biologist and Vertebrate Nutritional Physiologist/Ecologist.
Descriptions of both vacancies follow below and you can see these
announcements at this URL: http://zorba.uafadm.alaska.edu/iab/index.html.

Please respond to the appropriate Chair of each search committee for more
information.
--------------------------------------------------------------------------
CELL & MOLECULAR BIOLOGY

DEPARTMENT OF BIOLOGY & WILDLIFE
INSTITUTE OF ARCTIC BIOLOGY
UNIVERSITY OF ALASKA
FAIRBANKS ALASKA

The Department of Biology and Wildlife and Institute of Arctic Biology at
the University of Alaska Fairbanks seek qualified applicants for
the tenure-track position of Assistant Professor of Cellular/Molecular
Biology. The appointee is expected to establish a productive research
program at the cellular or molecular level that ideally will integrate
with existing faculty interests including: high latitude physiology,
neurobiology, endocrinology, or chronobiology. The successful applicant
will be expected to teach two courses/year including cell biology
and an additional course such as developmental biology or molecular
biology, and to supervise graduate students. An earned Ph.D. in
biology or related field is mandatory; post-doctoral and teaching
experience are preferred.

Initial support for graduate student teaching assistants, laboratory
space, and start-up funds are included in this appointment which is
expected to begin in fall of 1997. Qualified women and minorities are
encouraged to apply.

Send applications including: statements of research interest, teaching
philosophy, curriculum vitae, and three letters of reference by January
15, 1997 to:

Dr. Gerald Shields
Chair, Cellular/Molecular Search
Department of Biology and Wildlife and
Institute of Arctic Biology,
University of Alaska Fairbanks
Fairbanks AK 99775
(907) 474-7656, Fax
(907) 474-6967
E-mail: gshields@redback.lter.alaska.edu

The University of Alaska Fairbanks is the Land Grant,
Sea Grant, and Space Grant institution in Alaska.

The University of Alaska is an Educational Institution and an EEO and
Affirmative Action Employer. Your Application for Employment
with The University of Alaska May Be Subject to Public Disclosure
...........................................................................



Tenure Track Position
Vertebrate Nutritional
Physiologist/Ecologist


The Department of Biology and Wildlife and the Institute of Arctic
Biology at the University of Alaska Fairbanks seek a faculty member for
a tenure-track position at the level of ASSISTANT PROFESSOR. Candidates
are expected to have an earned doctorate in Biology or closely
related field with expertise in both laboratory and field research, and
interests in working at levels from molecular to the whole animal. The
successful candidate will be a critical member of a group of researchers
by bridging the disciplines of wildlife ecology, physiology, and
molecular biology. This individual also will be expected to:

develop a strong externally funded research program, mentor graduate
students, and
teach two courses per year, including Nutritional and
Physiological Ecology of Wildlife.

Extensive facilities are available including:
captive research herds of muskox and caribou (Large Animal Research
Station),  a remote field station north of the Arctic circle (Toolik
Field Station), animal vivarium equipped to conduct research in
environmental physiology, and a Core DNA Sequencing Facility.

We encourage candidates with the potential for forming collaborative
research programs with applied resource agencies and with existing
faculty having interests in physiological and ecological adaptations to
northern environments and ruminant physiological ecology. We especially
encourage the application of qualified women and minority candidates. The
possibility exists for a shared tenure-track position forcandidates with
spouses. Preference will be given to candidates with
postdoctoral and university teaching experience, and a strong publication
record.

To apply, send curriculum vitae, statements of research interests and
teaching philosophy, copies of pertinent reprints, and have three letters
of reference sent to:

Dr. James Sedinger
Search Chair
Institute of Arctic Biology
University of Alaska Fairbanks
Fairbanks, AK
99775-7000
(907) 474-6598
E-mail: ffjss@aurora.alaska.edu

Closing date: 15 December 1996

From owner-evolution@net.bio.net Sun Dec 08 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!howland.erols.net!math.ohio-state.edu!jussieu.fr!u-psud.fr!univ-lyon1.fr!pasteur.fr!infobiogen.fr!lovelace.infobiogen.fr!coulier
From: Francois Coulier <coulier@infobiogen.fr>
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: Mon, 9 Dec 1996 20:55:31 +0100
Organization: "GIS INFOBIOGEN, 7 rue Guy Moquet BP8, 94801 VILLEJUIF, France"
Lines: 46
Message-ID: <Pine.SOL.3.95.961209205210.27381A-100000@lovelace.infobiogen.fr>
References: <Pine.OSF.3.90.961209164511.6353A-100000@thunder>
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To: Wolfgang Wuster <bss166@bangor.ac.uk>
In-Reply-To: <Pine.OSF.3.90.961209164511.6353A-100000@thunder>

On Mon, 9 Dec 1996, Wolfgang Wuster wrote:

> 
> I was wondering whether there is a widespread consensus among molecular
> biologists regarding the extent to which published sequences can be
> re-used, and published in one's own name without it becoming a case of
> plagiarism. 
> 
> For instance, if researcher A is working on the phylogeny of a group of
> organisms, would he be within his rights to to download a bunch of DNA
> sequences for the same group of organisms, obtained by researcher B,
> integrate them within his analysis, and pubish the results without
> discussion with the researcher who spent years obtaining the sequences in
> the first place? Are there any limits depending on what proportion of 
> another worker's data one uses?
> 
> I'd be grateful for any input from readers of the ng/list.
> --
> Wolfgang Wuster
> School of Biological Sciences, University of Wales, Bangor, UK
> e-mail: w.wuster@bangor.ac.uk
> 
> Thought for the day: If you see a light at the end of the tunnel,
> it is probably a train coming your way.
> 
> 
I would say that when a sequence is release in a public database, it fall
in the bublic domain, and therefore can be used to the same extent as a
sequence published on paper.
It is not the same with private databases (i.e. TIGR database), but for
accessing these, you need to sign an agreement on the first place, which
usually restrict your right to use the sequences.

 *  *  *  *  *  *  *  *  *  *  *  *  *
Francois Coulier
INSERM Unite 119
27 bd Lei Roure
13009 Marseille
France

tel 33 (0) 4 91 75 84 11
fax 33 (0) 4 91 26 03 64)
email: coulier@infobiogen.fr
*  *  *  *  *  *  *  *  *  *  *  *  *



From owner-evolution@net.bio.net Sun Dec 08 22:00:00 1996
Path: biosci!rutgers!uwm.edu!cs.utexas.edu!howland.erols.net!www.nntp.primenet.com!nntp.primenet.com!mindspring!uunet!in2.uu.net!192.109.159.3!news.gtn.com!inn.aball.de!on-line.leine.de!yamato.leine.de
From: mapstool@B-52.zer
Newsgroups: bionet.molbio.evolution
Subject: Autoinit-Mail
Date: 8 Dec 96 01:51:44 +0100
Message-ID: <239DD22014MM001@mapstool.chatline.zer>
X-Gateway: ZCONNECT UH online.leine.de [UUCPfZ V5.81 U055]
Lines: 2

!


From owner-evolution@net.bio.net Sun Dec 08 22:00:00 1996
Path: biosci!bcm.tmc.edu!watson!roxanney
From: roxanney@bcm.tmc.edu (Roxanne A Yamashita)
Newsgroups: bionet.molbio.evolution
Subject: Aspergillus in the wild
Date: 9 Dec 1996 20:37:56 GMT
Organization: Baylor College of Medicine, Houston, Tx
Lines: 11
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NNTP-Posting-User: roxanney
X-Newsreader: TIN [version 1.2 PL2]

Dear Friends,
Hi!  I posted a question about 2 weeks ago and got three responses.  I
would like to know exactly waht is happening on plates where a wild type
strain like GR5 or R153 sectors. Are rearrangements, etc being made.  I
would like to know this because I have made a number of mutants that show
slowed growth and increase sectoring.  Please send any ideas you have to
me at:
roxanney@bcm.tmc.edu


Thank you for your time! 

From owner-evolution@net.bio.net Sun Dec 08 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!usenet.eel.ufl.edu!warwick!yama.mcc.ac.uk!hydraulix.bangor.ac.uk!manager	
From: Wolfgang Wuster <bss166@bangor.ac.uk>
Newsgroups: bionet.molbio.evolution
Subject: Use of sequence databases - ethics?
Date: Mon, 9 Dec 1996 16:51:30 +0000 (GMT)
Organization: University of Wales, Bangor.
Lines: 22
Message-ID: <Pine.OSF.3.90.961209164511.6353A-100000@thunder>
NNTP-Posting-Host: thunder.bangor.ac.uk
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X-Sender: bss166@thunder


I was wondering whether there is a widespread consensus among molecular
biologists regarding the extent to which published sequences can be
re-used, and published in one's own name without it becoming a case of
plagiarism. 

For instance, if researcher A is working on the phylogeny of a group of
organisms, would he be within his rights to to download a bunch of DNA
sequences for the same group of organisms, obtained by researcher B,
integrate them within his analysis, and pubish the results without
discussion with the researcher who spent years obtaining the sequences in
the first place? Are there any limits depending on what proportion of 
another worker's data one uses?

I'd be grateful for any input from readers of the ng/list.
--
Wolfgang Wuster
School of Biological Sciences, University of Wales, Bangor, UK
e-mail: w.wuster@bangor.ac.uk

Thought for the day: If you see a light at the end of the tunnel,
it is probably a train coming your way.

From owner-evolution@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!MOLBIOL.UCT.AC.ZA!ed
From: ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki")
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 10 Dec 1996 05:11:51 -0800
Organization: Dept Microbiology, UCT
Lines: 27
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <m0vXRGw-0000L0C@uctmail.uct.ac.za>
Reply-To: ed@molbiol.uct.ac.za
NNTP-Posting-Host: net.bio.net

> From:          Wolfgang Wuster <bss166@bangor.ac.uk>
> Subject:       Use of sequence databases - ethics?
> Date:          Mon, 9 Dec 1996 16:51:30 +0000 (GMT)

> 
> I was wondering whether there is a widespread consensus among molecular
> biologists regarding the extent to which published sequences can be
> re-used, and published in one's own name without it becoming a case of
> plagiarism. 

I have been in exactly this position a couple of times, with
sequence analyses of both poty- and geminiviruses - and I took the
view that if a sequence is published in a database (which with plant
viruses usually means it has been published in print as well), then
it is "public domain" in that I can use it as long as I correctly
cite who sequenced it.  I think this constitutes "fair use" as far as 
databased sequences are concerned.


                     Ed Rybicki, PhD  
      Dept Microbiology     |   ed@molbiol.uct.ac.za   
   University of Cape Town  | rybicki@uctvms.uct.ac.za
   Private Bag, Rondebosch  |  phone: x27-21-650-3265
      7700, South Africa    |   fax: x27-21-689 7573
    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
                                        
    "Out here on the perimeter, there are no stars..."

From owner-evolution@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!www.nntp.primenet.com!nntp.primenet.com!news.sprintlink.net!news-peer.sprintlink.net!howland.erols.net!math.ohio-state.edu!news.cis.ohio-state.edu!nntp.sei.cmu.edu!fs7.ece.cmu.edu!casaba.srv.cs.cmu.edu!das-news2.harvard.edu!oitnews.harvard.edu!purdue!haven.umd.edu!hecate.umd.edu!phelix.umd.edu!not-for-mail
From: moths@Glue.umd.edu (Andrew Mitchell)
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 9 Dec 1996 16:12:13 -0500
Organization: Project Glue, University of Maryland, College Park, MD
Lines: 15
Message-ID: <58hvbd$91n@phelix.umd.edu>
References: <Pine.OSF.3.90.961209164511.6353A-100000@thunder> <Pine.SOL.3.95.961209205210.27381A-100000@lovelace.infobiogen.fr>
NNTP-Posting-Host: phelix.umd.edu

Surely once you publish a DNA sequence it becomes part of the public
domain, and anybody can use it in a manner they see fit (eg. phylogenetic
analysis), as long as they cite their source - otherwise there appears to
be no point in publishing sequences in the first place.  DNA sequence data
are no different in this regard from descriptions of morphological
characters, being simply observations of tangible biological phenomena. 

*******************************************************************************
Andrew Mitchell
Department of Entomology            E-MAIL: moths@phelix.umd.edu
University of Maryland
College Park, MD 20742
U.S.A.
*******************************************************************************


From owner-evolution@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!agate!howland.erols.net!feed1.news.erols.com!worldnet.att.net!uunet!in2.uu.net!128.250.1.21!munnari.OZ.AU!news.ecn.uoknor.edu!news.ou.edu!aardvark.ucs.ou.edu!roossinck
From: roossinck@aardvark.ucs.ou.edu (ROOSSINCK,MARILYN)
Newsgroups: bionet.molbio.evolution
Subject: Postdoctoral Position
Date: 10 Dec 1996 09:22 CST
Organization: University of Oklahoma - University Computing Services
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News-Software: VAX/VMS VNEWS 1.41    

POSTDOCTORAL FELLOW


Mechanisms of Viral Evolution


	A postdoctoral scientist is sought to fill a position at the Samuel
Roberts Noble Foundation, to join a team of scientists studying the molecular
mechanisms of viral evolution using members of the plant Cucumovirus  genus. 

Requirements:  A Ph.D. degree in Virology, Molecular Biology, or related area. 
Experience in Virology or Molecular Evolution helpful.

Salary and Apointment:  Base salary of $24,000/year plus benefits, increasing
with experience, with funding available for 3 years. 

Starting Date:  January 1997

Please send a complete CV, with the names, addresses, phone numbers and e-mail
addresses of at least three referees

Apply to:	
	Dr. Marilyn J. Roossinck
	Plant Biology Division
	The Samuel Roberts Noble Foundation
	P.O. Box 2180
	Ardmore, OK  73402
	Phone:  405 223-5810
	FAX:  405 221-7380
	e-mail:  mroossinck@noble.org


From owner-evolution@net.bio.net Mon Dec 09 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!news.bbnplanet.com!su-news-hub1.bbnplanet.com!news.sgi.com!esiee.fr!jussieu.fr!lepesant1.ijm.jussieu.fr!user
From: burmeste@ccr.jussieu.fr (Thorsten Burmester)
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 10 Dec 1996 20:59:26 GMT
Organization: Institut Jacques-Monod
Lines: 24
Distribution: world
Message-ID: <burmeste-1012962201030001@lepesant1.ijm.jussieu.fr>
References: <m0vXRGw-0000L0C@uctmail.uct.ac.za>
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Mime-Version: 1.0
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>> I was wondering whether there is a widespread consensus among molecular
>> biologists regarding the extent to which published sequences can be
>> re-used, and published in one's own name without it becoming a case of
>> plagiarism. 
>
>I have been in exactly this position a couple of times, with
>sequence analyses of both poty- and geminiviruses - and I took the
>view that if a sequence is published in a database (which with plant
>viruses usually means it has been published in print as well), then
>it is "public domain" in that I can use it as long as I correctly
>cite who sequenced it.  I think this constitutes "fair use" as far as 
>databased sequences are concerned.

Dear all,

And what is the status of a _patented_ sequence in GenBank etc.? May one
use it e.g. for phylogenetic analysis as if they were "public domain"?

-- 
Thorsten Burmester              Tel: (+33) 1 44 27 40 94
Institut Jacques-Monod          Fax: (+33) 1 44 27 52 65             
CNRS et Universite Paris 7    email: burmeste@ccr.jussieu.fr (preferred)
2 place Jussieu                   or tburmest@infobiogen.fr
F-75251 Paris CEDEX 05, France

From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
Path: biosci!rutgers!uwm.edu!www.nntp.primenet.com!nntp.primenet.com!usenet.eel.ufl.edu!warwick!news.nott.ac.uk!evol.nott.ac.uk!pdxkrb
From: pdxkrb@evol.nott.ac.uk (Keith Bradnam)
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 11 Dec 1996 22:38:50 GMT
Organization: Department of Genetics, University of Nottingham UK.
Lines: 31
Message-ID: <58nd5q$d2t@paperboy.ccc.nottingham.ac.uk>
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NNTP-Posting-Host: evol.gene.nottingham.ac.uk

Ed Rybicki <ed@molbiol.uct.ac.za> wrote:
>> From:          Wolfgang Wuster <bss166@bangor.ac.uk>
>> I was wondering whether there is a widespread consensus among molecular
>> biologists regarding the extent to which published sequences can be
>> re-used, and published in one's own name without it becoming a case of
>> plagiarism. 
>
>I have been in exactly this position a couple of times, with
>sequence analyses of both poty- and geminiviruses - and I took the
>view that if a sequence is published in a database (which with plant
>viruses usually means it has been published in print as well), then
>it is "public domain" in that I can use it as long as I correctly
>cite who sequenced it.  I think this constitutes "fair use" as far as 
>databased sequences are concerned.


I think it would get rather unfeasible to end up citing
all references to all sequences referred to in any given study.
This is particular true when you are dealing with analyses that
compare whole chromosomes or even whole genomes.  This sort
of genome anaylis will continue with the advent of more genome 
sequences being published.  For genomes such as yeast, the total number
of references needed to make sure all sequencing groups had been
acknowledged would be immense.  

Keith B.
-- 
-_-_-_-_-_-_-   The strongest of hearts, are easily broken,                   
  -_-_-_-_-      by the softest of words, so easily spoken 
    -_-_-                                         
      -  	     http://evol.nott.ac.uk/~pdxkrb/ 

From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
Path: biosci!rutgers!gatech!EU.net!usenet2.news.uk.psi.net!uknet!usenet1.news.uk.psi.net!uknet!uknet!newsfeed.ed.ac.uk!singer.cent.gla.ac.uk!b-cohen.molgen.gla.ac.uk!user
From: gbga13@udcf.gla.ac.uk (B.L.Cohen)
Newsgroups: bionet.molbio.evolution
Subject: Re: DCSE-Nexus-Treecon-help!
Date: 11 Dec 1996 17:10:10 GMT
Organization: Genetics, University of Glasgow
Lines: 28
Message-ID: <gbga13-1112961710060001@b-cohen.molgen.gla.ac.uk>
References: <3290653D.83C@ed.ac.uk> <gbga13-2811961745430001@b-cohen.molgen.gla.ac.uk> <32A54CD7.6307@uia.ua.ac.be>
NNTP-Posting-Host: b-cohen.molgen.gla.ac.uk

And I am very embarrassed to have written that because I realised almost
at once that it was an unfriendly, uncharitable and badly expressed
comment.

Indeed, the Antwerp files used to be convertible into standard formats
only with extreme difficulty, and I was careless about stating the current
position, with which I am not very familiar.

Apologies to my friends (ex-friends?) in Antwerp!

In article <32A54CD7.6307@uia.ua.ac.be>, nelissen@uia.ua.ac.be wrote:

> B.L.Cohen wrote:
> 
> > Unlikely, because the Antwerp group have been very bad about/ignorant of
> > interchange formats.
> 
>         Please do not make statements that are completely incorrect. Both
> TREECON and DCSE can convert between different file formats. So it is
> you who is ignorant about the possibilities of TREECON and DCSE.

-- 
Bernie Cohen                   Phone (+44) (0)141 339 8855 ext. 5103/5101
Molecular Genetics              Fax               330 5994
University of Glasgow
56 Dumbarton Rd,
Glasgow G11 6NU
Scotland, UK.

From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
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From: pingouin@crystal.u-strasbg.fr (Francois Jeanmougin)
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 11 Dec 1996 08:00:57 GMT
Organization: IGBMC
Lines: 26
Message-ID: <58lpnp$6q0@arcturus.ciril.fr>
References: <m0vXRGw-0000L0C@uctmail.uct.ac.za>
  <burmeste-1012962201030001@lepesant1.ijm.jussieu.fr>
NNTP-Posting-Host: crystal.u-strasbg.fr
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X-Newsreader: knews 0.9.6

In article <burmeste-1012962201030001@lepesant1.ijm.jussieu.fr>,
	burmeste@ccr.jussieu.fr (Thorsten Burmester) writes:
[...]
>And what is the status of a _patented_ sequence in GenBank etc.? May one
>use it e.g. for phylogenetic analysis as if they were "public domain"?
[...]

	I think it's public domain. You can use it for research, but you
can't use it for commercial applications. I don't think you can sale
your phylogenetic analysis, so it's a non-profit use. The only thing I
found about that at NCBI is :
	"The patent sequences are from the U.S. Patent and Trademark
Office and from the European Patent Office and are being entered into
the database as part of an ongoing cooperative project among the U.S.,
European, and Japanese patent offices and the sequence databases."
	So... I anyone know how this works...We have patented sequences
in some team in the building. I can ask.
							Francois.
-- 
Francois Jeanmougin
Service de bioinformatique / bioinformatics service
IGBMC BP 163 67404 Illkirch France
tel :(France) 03 88 65 32 71 / (international) (+33) 3 88 65 32 71
e-mail : jeanmougin@igbmc.u-strasbg.fr
"C'est pas parcequ'on monte au banc, qu'il faut descendre a jeun." (Thiefaine)


From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
Path: biosci!MOLBIOL.UCT.AC.ZA!ed
From: ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki")
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 10 Dec 1996 23:55:40 -0800
Organization: Dept Microbiology, UCT
Lines: 18
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <m0vXjV3-0004TjC@uctmail2.uct.ac.za>
Reply-To: ed@molbiol.uct.ac.za
NNTP-Posting-Host: net.bio.net

> From:          burmeste@ccr.jussieu.fr (Thorsten Burmester)
> Subject:       Re: Use of sequence databases - ethics?
> And what is the status of a _patented_ sequence in GenBank etc.? May one
> use it e.g. for phylogenetic analysis as if they were "public domain"?

If it is in GenBank, it is published: one can certainly refer to 
accession numbers in a publication, so why shouldn't one use the 
sequence in an analysis?  It's not as if one is actually synthesising 
the sequence and using it for expression purposes.

                     Ed Rybicki, PhD  
      Dept Microbiology     |   ed@molbiol.uct.ac.za   
   University of Cape Town  | rybicki@uctvms.uct.ac.za
   Private Bag, Rondebosch  |  phone: x27-21-650-3265
      7700, South Africa    |   fax: x27-21-689 7573
    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
                                        
    "Out here on the perimeter, there are no stars..."

From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!online.no!sn.no!nntp.uio.no!news-feed.inet.tele.dk!enews.sgi.com!news.sgi.com!su-news-hub1.bbnplanet.com!news.bbnplanet.com!cam-news-hub1.bbnplanet.com!howland.erols.net!swrinde!ihnp4.ucsd.edu!scripps.edu!NewsWatcher!user
From: anthonyp@scripps.edu (Anthony J. Pelletier, Ph.D.)
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: Wed, 11 Dec 1996 08:23:04 -0800
Organization: The Scripps Research Institute
Lines: 22
Message-ID: <anthonyp-1112960823040001@137.131.4.62>
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In article <58505p$oi7@sjx-ixn10.ix.netcom.com>, Jeffrey Allan Simon 
> Fascinating Ed, but tell me, what is the name of this new species that
has "evolved?" 

Name of a new species?  That's easy:  Triticum estivum.  There are more. 
But, I imagine you will find reasons to dismiss all of them.


> but natural selection is just as compatible with creation. 

Well, OF COURSE IT IS. That's why creation is not a scientific hypothesis.
Everything is consistent with creation.  Afterall, you believe in an
omnipotent god, don't you?  So, there can be nothing that God cannot have
done, right?

-- 
Anthony J. Pelletier, Ph.D.
Assistant Member, Department of Cell Biology
The Scripps Research Institute
La Jolla, CA

anthonyp@scripps.edu

From owner-evolution@net.bio.net Tue Dec 10 22:00:00 1996
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Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Message-ID: <32AF3D3D.2755@infect.dmed.iupui.edu>
From: "Diane R. Stothard" <dianes@infect.dmed.iupui.edu>
Date: Wed, 11 Dec 1996 18:01:17 -0500
References: <Pine.OSF.3.90.961209164511.6353A-100000@thunder> <Pine.SOL.3.95.961209205210.27381A-100000@lovelace.infobiogen.fr>
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I have published papers with others' sequences in them. I think they are 
public domain, yes, but I have always cited the references for data that 
are not mine. In this way, the data can be used but credit is still 
given. I think it would be a mistake not to use data in databases...it 
would be like ignoring it. Sometimes, additional data can support or 
refute a previous hypothesis. Therefore, it is always good to include 
whatever is available.


Francois Coulier wrote:
> 
> On Mon, 9 Dec 1996, Wolfgang Wuster wrote:
> 
> >
> > I was wondering whether there is a widespread consensus among molecular
> > biologists regarding the extent to which published sequences can be
> > re-used, and published in one's own name without it becoming a case of
> > plagiarism.
> >
> > For instance, if researcher A is working on the phylogeny of a group of
> > organisms, would he be within his rights to to download a bunch of DNA
> > sequences for the same group of organisms, obtained by researcher B,
> > integrate them within his analysis, and pubish the results without
> > discussion with the researcher who spent years obtaining the sequences in
> > the first place? Are there any limits depending on what proportion of
> > another worker's data one uses?
> >
> > I'd be grateful for any input from readers of the ng/list.
> > --
> > Wolfgang Wuster
> > School of Biological Sciences, University of Wales, Bangor, UK
> > e-mail: w.wuster@bangor.ac.uk
> >
> > Thought for the day: If you see a light at the end of the tunnel,
> > it is probably a train coming your way.
> >
> >
> I would say that when a sequence is release in a public database, it fall
> in the bublic domain, and therefore can be used to the same extent as a
> sequence published on paper.
> It is not the same with private databases (i.e. TIGR database), but for
> accessing these, you need to sign an agreement on the first place, which
> usually restrict your right to use the sequences.

From owner-evolution@net.bio.net Wed Dec 11 22:00:00 1996
Path: biosci!MOLBIOL.UCT.AC.ZA!ed
From: ed@MOLBIOL.UCT.AC.ZA ("Ed Rybicki")
Newsgroups: bionet.molbio.evolution
Subject: Re: Use of sequence databases - ethics?
Date: 12 Dec 1996 00:35:46 -0800
Organization: Dept Microbiology, UCT
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> From:          pdxkrb@evol.gene.nottingham.ac.uk (Keith Bradnam)
> Subject:       Re: Use of sequence databases - ethics?
> I think it would get rather unfeasible to end up citing
> all references to all sequences referred to in any given study.
...For genomes such as yeast, the total number
> of references needed to make sure all sequencing groups had been
> acknowledged would be immense.  

An accession number - or group thereof - is a reference, in that it 
leads straight to the authors of any sequence(s).  As long as some ay 
is figured for credit to be given for citation of accession numbers, 
I can see no problem for their use instead of list of names.

                     Ed Rybicki, PhD  
      Dept Microbiology     |   ed@molbiol.uct.ac.za   
   University of Cape Town  | rybicki@uctvms.uct.ac.za
   Private Bag, Rondebosch  |  phone: x27-21-650-3265
      7700, South Africa    |   fax: x27-21-689 7573
    WWW URL: http://www.uct.ac.za/microbiology/ed.html      
                                        
    "Out here on the perimeter, there are no stars..."

From owner-evolution@net.bio.net Wed Dec 11 22:00:00 1996
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From: teachertom@aol.com (TeacherTom)
Newsgroups: bionet.molbio.evolution
Subject: Re: Anyone Seen Evolution?
Date: 12 Dec 1996 01:44:27 GMT
Organization: AOL http://www.aol.com
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I was Bill Clinton evolve into a moderate conservative Republican.  That
should clinch any doubt about the truth of evolution.


From owner-evolution@net.bio.net Thu Dec 12 22:00:00 1996
Path: biosci!UCRWCU.RWC.UC.EDU!cooperlj
From: cooperlj@UCRWCU.RWC.UC.EDU (Lesta Cooper-Freytag)
Newsgroups: bionet.molbio.evolution
Subject: Unsubscribe
Date: 13 Dec 1996 09:55:39 -0800
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        Please unsubscribe me until Jan. 10, 1997.

Lesta J. Cooper-Freytag
E-MAIL: cooperlj@ucrwcu.rwc.uc.edu



From owner-evolution@net.bio.net Thu Dec 12 22:00:00 1996
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From: krutovsk@fsl.orst.edu (Konstantin Krutovskii)
Newsgroups: bionet.molbio.evolution
Subject: Faculty Research Assistant/Plant Molecular Geneticist
Date: Wed, 11 Dec 1996 23:01:19
Organization: Forestry Sciences Lab
Lines: 102
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Position Number: 002-825

     Faculty Research Assistant/Research Associate, Plant Molecular 
     Genetics

     Location: Department of Forest Science, Oregon State University, 
     Corvallis, OR

     Date Available: March 1, 1997

     Closing Date: January 13, 1997 

     Position Responsibilities:     

     We seek a molecular geneticist to work as part of the Tree Genetic 
     Engineering Research Cooperative (TGERC) at Oregon State University. 
      The TGERC is a consortium supported by 13 Members, mostly forest 
     industries, that are seeking improved means for genetic manipulation 
     of poplar trees.  The applicant's primary responsibility in the Coop 
     will be production of novel plasmid constructs to be used in 
     Agrobacterium transformation, and analysis of the transgenic trees 
     produced.  They will work closely with other TGERC staff doing tissue 
     culture, transformation, and gene isolation.  The constructs will be 
     composed primarily of floral homeotic genes intended for induction of 
     sexual sterility; however, they will also work with other genes 
     relevant to ongoing Cooperative projects on insect, disease, and 
     herbicide resistance.  

     Specifically, responsibilities will include: 

     1.   Development of strategies for producing binary constructs with 
     various genes for Agrobacterium transformation of poplar.  

     2.   Configuration of genes and plasmid vectors, verifying 
     structure/sequence, and transformation into Agrobacterium strains.  

     3.   Analysis of transgenic plants for gene incorporation, 
     expression, and delivery of desired traits.  

     5.   Supervision of students, technicians, and other workers to 
     help carry out laboratory studies.

     6.   Participation in writing Coop reports and publications for 
     scientific journals.  

     7.   Effective oral communication of results at annual Coop meeting 
     and other scientific forums.  

     8.   Collaboration with Coop staff to write grants to obtain 
     supplemental funding for research.  

     Education and experience:    

     A B.S. degree in molecular genetics or a related field, and at 
     least two years of experience with recombinant DNA manipulation, 
     are essential.  Knowledge of plant molecular biology and experience 
     in plant transformation techniques are desirable.  Experience and 
     demonstrated competence in the following areas are particularly 
     important:

     1.   Advanced recombinant DNA manipulation of plasmid vectors. 

     2.   Molecular analyses, including DNA sequencing, PCR, and 
     Southern, northern, and western blots. 

     3.   Written and oral communication. 

     4.   Collaboration with colleagues, subordinates, and superiors. 

     5.   Long- and short-term organization and planning of work. 

     Employment conditions:

     The job will be filled at the rank of either Research Assistant 
     (B.S., M.S., or Ph.D.) or Research Associate (Ph.D.), depending 
     upon career track of candidate, in the Department of Forest Science 
     at Oregon State University.  We are also open to the applicant 
     taking a more scientific role in the work, as would Ph.D.s in a 
     Research Associate position (e.g., writing papers for publication), 
     or a more technical role, as would most with only a B.S. (limited 
     writing, mostly directed lab work).  The appointment is a 
     full-time, 12-month, fixed-term position; reappointment is at the 
     discretion of the Dean.  The employee will report directly to 
     Cooperative Director.  The salary will be in the range of $24,000 
     to $32,004/year, depending on qualifications.  Medical, dental, and 
     life insurance plans are available.  

     To apply:

     Send a letter of application describing your qualifications and 
     interests in the position, a resume, transcripts, and the names, 
     email addresses, and fax numbers of four references by January 13, 
     1997 to Sandra Lewis, Office Manager, Dept. of Forest Science, 020 
     Forestry Sciences Laboratory, Oregon State University, Corvallis, 
     OR 97331-7501.  For more information contact Prof. Steve Strauss, 
     phone 541/737-6578, email strauss@FSL.orst.edu, fax 541/737-1393.  


     OREGON STATE UNIVERSITY IS AN AFFIRMATIVE ACTION/EQUAL OPPORTUNITY 
     EMPLOYER AND HAS A POLICY OF BEING RESPONSIVE TO THE NEEDS OF 
     DUAL-CAREER COUPLES.  


From owner-evolution@net.bio.net Fri Dec 13 22:00:00 1996
Path: biosci!daresbury!not-for-mail
From: Wolfgang Wuster <w.wuster@bangor.ac.uk>
Newsgroups: bionet.molbio.evolution
Subject: Re: Post your AD to 26,000 newsgroups at once for $35.00 , 16551324033101655
Date: 14 Dec 1996 10:35:13 -0000
Lines: 21
Sender: lpddist@mserv1.dl.ac.uk
Distribution: bionet
Message-ID: <58tvt1$7av@mserv1.dl.ac.uk>
X-Sender: bss166@thunder
Original-To: IGMG <igmg@HoTMAIL.CoM>

On Fri, 13 Dec 1996, IGMG wrote:

> To reply to this message use the email address at the end=85=20
>=20
> I have developed a Windows 95 and Windows NT Internet Marketing Solution =
that will
> revolutionize the way you conduct direct marketing over the Internet. Wit=
h one sophisticated
> program your company can contact over 3 MILLION Internet Users.  More det=
ail later, right

Imagine getting your sorry ass flamed by only 0.1% of those users for=20
spamming this into their group - should be quite an experience...

--
Wolfgang Wuster
School of Biological Sciences, University of Wales, Bangor, UK
e-mail: w.wuster@bangor.ac.uk

Thought for the day: If you see a light at the end of the tunnel,
it is probably a train coming your way.

From owner-evolution@net.bio.net Sat Dec 14 22:00:00 1996
Path: biosci!rutgers!uwm.edu!news-peer.gsl.net!news.gsl.net!news-hk.gsl.net!news.gsl.net!newsgate.cuhk.edu.hk!news.att.net.hk!elausrv2.att.net.au!zonk.geko.net.au!usenet
From: Neil Aitchison <mec@adelaide.on.net>
Newsgroups: bionet.molbio.evolution
Subject: truth??...evolution??
Date: Mon, 16 Dec 1996 03:03:49 -0800
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Hi....I'm wondering if evolution is true or not....this web site says 
it's not....


-> http://www.on.net/users/mec/answers/_3_sci.htm

What do you think?

From owner-evolution@net.bio.net Sun Dec 15 22:00:00 1996
Path: biosci!daresbury!not-for-mail
From: Wolfgang Wuster <w.wuster@bangor.ac.uk>
Newsgroups: bionet.molbio.evolution
Subject: Re: truth??...evolution??
Date: 16 Dec 1996 09:20:33 -0000
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Original-To: Neil Aitchison <mec@adelaide.on.net>

On Mon, 16 Dec 1996, Neil Aitchison wrote:

> Hi....I'm wondering if evolution is true or not....this web site says 
> it's not....
> 
> -> http://www.on.net/users/mec/answers/_3_sci.htm

Wow - when someone told me that the bible says that evolution is not 
true, I laughed. But if a web site says so - now that's authoritative!

Take it to talk.origins, or, better than that, get a clue and a life.
--
Wolfgang Wuster
School of Biological Sciences, University of Wales, Bangor, UK
e-mail: w.wuster@bangor.ac.uk

Thought for the day: If you see a light at the end of the tunnel,
it is probably a train coming your way.

From owner-evolution@net.bio.net Mon Dec 16 22:00:00 1996
Path: biosci!rutgers!uwm.edu!www.nntp.primenet.com!nntp.primenet.com!howland.erols.net!vixen.cso.uiuc.edu!usenet
From: dneece@students.uiuc.edu (David Neece)
Newsgroups: bionet.molbio.evolution
Subject: Need reformatting program for DNASIS
Date: 17 Dec 1996 16:30:38 GMT
Organization: University of Illinois
Lines: 16
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Hello,

I'm looking for a Windows based program to reformat DNA sequence files before 
pasting them into DNASIS.  Specifically, I need something that will take 
line-breaks and spaces out of text file sequences.
All suggestions appreciated,

Dave.
________________________________________
David J. Neece,      Research Specialist
Department of Animal Sciences
University of Illinois
"There is no meaning; it's all just a 
bunch of stuff that happened." -Homer
                                 (Simpson)


From owner-evolution@net.bio.net Mon Dec 16 22:00:00 1996
Path: biosci!rutgers!csn!nntp-xfer-1.csn.net!magnus.acs.ohio-state.edu!infoserver.bgsu.edu!m254-152.bgsu.edu!user
From: anikiti@opie.bgsu.edu (Alex Nikitin)
Newsgroups: bionet.molbio.evolution
Subject: Re: truth??...evolution??
Date: Tue, 17 Dec 1996 12:01:20 +0200
Organization: Bowling Green State University
Lines: 58
Message-ID: <anikiti-1712961201200001@m254-152.bgsu.edu>
References: <32B52C95.2AC2@adelaide.on.net>
NNTP-Posting-Host: m254-152.bgsu.edu

In article <32B52C95.2AC2@adelaide.on.net>, Neil Aitchison
<mec@adelaide.on.net> wrote:

> Hi....I'm wondering if evolution is true or not....this web site says 
> it's not....
> 
> 
> -> http://www.on.net/users/mec/answers/_3_sci.htm
> 
> What do you think?

Although it is not wise to even attempt to answer such a question (no
offence), I'd like to mention a few things from that netpage mentioned in
the post, just for the fun of it, and give my brief point of view on each
of the points rised.

Quote 1:

"11. All Mankind came from One Woman. 

"Adam called his wife's name Eve : because she was the mother of all
living." Genesis 3:20. DNA is
found in every cell, in both the nucleus and the mitochondrion (energy
station). Mitochondrial DNA is
always and only inherited from the mother. Analysis of this DNA in humans
from all over the world
shows unmistakably that all humans on earth have inherited it from one
woman. This research was done
by Wilson, Cann, and Stoneking from the University of California, Berkeley."

Whoever whrote this should probably try to read the source again and also
get some background in population genetics and anthropology. The authors
of the mentioned investigation never claimed our mtDNA to decent from one
woman, it is plain impossible from a population genetics point of view.
Besides, the author of the quote did't mention Adam; according to that
logic, there had to be a single Adam, preferrably living in the same
georgaphical regin as mitochondrial Eve. There's a lot more to this
discussion, but it is mostly about the phylogenetic implications of
molecular findings, the basic knowledge of wich the author of the quote
lacks.

Quote 2 (talking about the tapeworm that can be found in pork meat):
"God, by forbidding people to eat or touch pork, shows His care for us. 
Question:How did the Bible know about the dangers of pork in 1500 BC? 
Answer: God wrote the Bible."

Well, how about salmonella in poultry? Bowine tapeworm? Whole bunch of
different parasites in mollusks? Why such a specificity? Besides, in
Eastern Europe pork is the major food source (that and potatoes), and they
are Christians too (most of them, anyway). Now, the question about how did
the Bible know of the dangers of eating pork is very simple to answer:
SOMEBODY TASTED PORK AND GOT SICK! It desn't require God to write the
Bible in order for people to understand such simple things, unless they
(people) are incredibly dumb, which, of course, was not the case.

Overall suggestion: don't try to use netpages like that for a guide
through science; either read the Bible, or read "Science" and "Nature",
the mixture of the two opposite points of view can be dangerous! :)

From owner-evolution@net.bio.net Mon Dec 16 22:00:00 1996
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From: inmanh@cogs.susx.ac.uk (Inman Harvey)
Newsgroups: bionet.molbio.evolution,bionet.neuroscience
Subject: ECAL97 Final CFP
Date: 17 Dec 1996 17:10:12 GMT
Organization: University of Sussex
Lines: 100
Distribution: world
Message-ID: <596k5k$49i@infa.central.susx.ac.uk>
NNTP-Posting-Host: rsunx.crn.cogs.susx.ac.uk
Xref: biosci bionet.molbio.evolution:5440 bionet.neuroscience:17259


Full details on our website http://www.cogs.susx.ac.uk/ecal97

                  FINAL CALL FOR PAPERS
       4th. EUROPEAN CONFERENCE ON ARTIFICIAL LIFE
                          ECAL97
             Brighton, UK, July 28-31 1997

This interdisciplinary conference aims to provoke new understandings of the
relationships between the natural and the artificial. Artificial Life is often
described as the endeavour to synthesize life-like phenomena in artificial
media in an attempt to establish a formal and general understanding of life.
In practice it is something much broader. At its core are exchanges of ideas
and blurring of boundaries between disciplines traditionally constrained to
just the natural or just the artificial.

ECAL97 will foster further cross-fertilisation and hopes to extend the
Artificial Life community by encouraging contributions from people involved in
the Arts and Humanities. The conference will involve oral presentations, both
invited and contributed, poster sessions, debates, exhibitions,
demonstrations, installations and related activities.

Scientific topics to be covered will include, but not be limited to, the list
below. Contributions from biologists are particularly welcome.

Self-organisation. Origins of Life. Prebiotic evolution. RNA Systems. Fitness
Landscapes. Natural Selection. Sexual Selection. Ecosystem evolution.
Evolutionary Optimisation. Evolutionary Computation. Immune Networks. Neural
Networks. Multicellular Development. Natural and Artificial Morphogenesis.
Learning and Development. Communication. Artificial Worlds. Simulations of
Ecological and Evolving Systems. Mobile Agents. Autonomous Robots.
Evolutionary Robotics. Software Agents. Collective Behaviour. Swarm
Intelligence. Cooperation. Evolution of Social Behaviour. Philosophical Issues
in Alife. Ethical problems.

NEW --- Publisher will now be: MIT Press/Bradford Books. Papers should not be
longer than 10 pages (including figures) in MIT Press format. Format
instructions and LaTeX template are available on our web-page. We encourage
paper submissions via the Internet (see web-page) though traditional paper is
also acceptable (4 hard-copies). Demonstrations, Videos, and proposals for
associated workshops are also welcomed.

IMPORTANT DATES
Feb 28, 1997     -- Submission deadline
Apr 12           -- Notification of acceptance
May 1            -- Camera-ready due
May 31           -- Early registration deadline
July 28-31, 1997 --  Conference dates

ECAL97 will be held in Brighton on the South Coast of England. There are good
travel connections; it is just one hour by train from London and conveniently
close to London Gatwick airport. The conference will be inside the Metropole
Hotel on Brighton seafront. Special accomodation rates will be available for
those staying at the hotel, with other cheaper accommodation available
elsewhere.

Please PRE-REGISTER your interest by filling out a form via our WWW site. All
new announcements will be emailed to those who have pre-registered, and will
also be available on this site:
http://www.cogs.susx.ac.uk/ecal97/

Conference organizers:   Phil Husbands and Inman Harvey
Local organization:      Medeni Fordham and Joseph Faith
Conference Secretariat:  Medeni Fordham
ECAL97
COGS, University of Sussex
Brighton BN1 9QH, UK

EMAIL: ecal97@cogs.susx.ac.uk

PROGRAM COMMITTEE

Riccardo Antonini (I) Randall D. Beer (US) Wolfgang Banzhaf (D) George Bekey
(US) Hugues Bersini (B) Maggie Boden (UK) Peter de Bourcier (UK) Paul Bourgine
(F) Rodney Brooks (US) Scott Camazine (D) Peter Cariani (US) Pablo Chacon (E)
Andy Clark (UK) Dave Cliff (UK) Michael Conrad (US) Holk Cruse (D) Jaques
Demongeot (F) Jean-L. Deneubourg (B) Michael Dyer (US) Claus Emmeche (DK)
Dario Floreano (CH) Terry Fogarty (UK) Walter Fontana (A) Brian C. Goodwin
(UK) Howard Gutowitz (US) Horst Hendriks-Jansen (UK) Paulien Hogeweg (NL)
George Kampis (H) Kunihiko Kaneko (JP) Hiroaki Kitano (JP) Chris Langton (US)
Antonio Lazcano (MX) Pier L. Luisi (CH) David McFarland (UK) Pattie Maes (US)
Barry McMullin (IE) Juan J. Merelo (E) Jean-Arcady Meyer (F) Eric Minch (US)
Melanie Mitchell (US) Federico Moran (E) Alvaro Moreno (E) Jim D. Murray (US)
Stefano Nolfi (I) Daniel Osorio (UK) Domenico Parisi (I) Howard Pattee (USA)
Rolf Pfeifer (CH) Steen Rasmussen (US) Tom Ray (JP) Robert Rosen (CA) Chris
Sander (D) Peter Schuster (D) Moshe Sipper (CH) Tim Smithers (E) M.V.
Srinivasan (AU) Luc Steels (B) John Stewart (F) Peter Todd (D) Jon Umerez (US)
Francisco Varela (F) Gunter Wagner (US) Barbara Webb (UK) Hans V. Westerhoff
(NL) Michael Wheeler (UK) William C. Wimsatt (US) Chris Winter (UK) Rene
Zapata (F)
====================================================================

NEW -- European Workshop on Learning Robots

EWLR-6, the 1997 European Workshop on Learning Robots, will be held in
association with ECAL97 on the day after, Friday August 1st 1997, in the same
location, the Metropole Hotel Brighton. The Call For Papers for EWLR-6 will be
issued some time in January 1997; for further information contact Andreas Birk
cyrano@arti14.vub.ac.be.
====================================================================

From owner-evolution@net.bio.net Mon Dec 16 22:00:00 1996
Path: biosci!bcm.tmc.edu!cs.utexas.edu!www.nntp.primenet.com!nntp.primenet.com!howland.erols.net!news-peer.gsl.net!news.gsl.net!portc01.blue.aol.com!newsstand.cit.cornell.edu!news.acsu.buffalo.edu!dsinc!netnews.upenn.edu!central.cis.upenn.edu!tandy
From: tandy@central.cis.upenn.edu (Tandy Warnow)
Newsgroups: bionet.molbio.evolution
Subject: postdoctoral and doctoral fellowships
Date: 17 Dec 1996 15:02:21 GMT
Organization: University of Pennsylvania
Lines: 269
Message-ID: <596clt$jhq@netnews.upenn.edu>
NNTP-Posting-Host: central.cis.upenn.edu


             Doctoral and Postdoctoral Fellowships 
                 in Computational Biology


The Computational Biology Training Program at the University
of Pennsylvania has several fellowships available for highly
qualified students and postdoctoral researchers.  No previous
experience with computational biology is required!  The
program enjoys the participation of many faculty throughout
the University, drawing from the schools  of Medicine,
Engineering, and Arts and Sciences, and has participants
from nearby Biotech companies as well.

For the doctoral fellowships, applicants should be interested
in pursuing a PhD in Computer Science, Biology, Genetics, Mathematics,
or Statistics.  Cross-disciplinary training is provided.

For postdoctoral fellowships, applicants should already have
a PhD in one of the relevant fields (see above), and should have
interest and ability in both scientific and quantitative 
reasoning.   Research areas of interest to the program
are primarily: multiple sequence alignment, sequence comparison,
molecular evolution and phylogenetics, bioinformatics, biological
databases, physical and genetic mapping, and statistical inference in Biology.

Additional information is given below.

**************************************************************
APPLICANTS FOR THE DOCTORAL PROGRAM: 
If you are applying for the doctoral programs, you will have to
apply directly to one of the participating departments.  We do not
offer an interdisciplinary PhD, but rather supplementary training.
Information on how to apply to a doctoral program is given below.
After you have applied to the appropriate doctoral program you should
contact us by email, letting us know which department you have
applied to.  We will keep track of your application, and if it
is accepted, we will consider you for funding through our training
program.

APPLICANTS FOR POSTDOCTORAL POSITIONS:
If you are applying for a postdoctoral position, please send us
the following: 
           (a)  Completed application form.
           (b)  Statement (maximum one page) of your research 
                interests, academic goals,  and why you are 
                interested in computational biology.
           (c)  Four letters of reference -- these should be 
                     sent directly by the referees.
           (d)  Curriculum vita.


                    Yours sincerely,


                       Dr. Warren Ewens (PI), 
                       Computational Biology Training Program
                       Department of Biology
                       University of Pennsylvania
                       Philadelphia PA 19104
                       




    University of Pennsylvania Training Program in
            Computational Biology



The University of Pennsylvania has established an 
interdisciplinary training program for PhD students 
and postdoctoral researchers in computational biology. 
Areas of  interest include:
     biological databases, 
     multiple sequence alignment, 
     molecular evolution and phylogeny construction, 
     physical and genetic mapping, 
     sequence search and analysis, 
     statistical methods, 
     discrete algorithms and combinatorial 
         optimization in biology.

The research training program provides core training
in molecular biology and genetics, discrete algorithms,
mathematical modelling, and probability and statistics,
so that important biological problems can be addressed
effectively through a collaborative effort between 
researchers in these different fields. 
Advanced training draws on the expertise of the faculty, and
includes both advanced seminars and laboratory research
opportunities.

Participating faculty include the following:



Peter Buneman (Computer and Information Science):
Programming languages: applicative 
and functional languages, type systems.

Fan Chung (Mathematics):
Combinatorics and algorithms.

Susan Davidson (Computer and Information Science):
Real-time database systems: language 
support and formal methods for distributed real-time programs.

Arthur Dunham (Biology): Mathematical models at the interface 
of physiological ecology and population dynamics.

Joe Ecker (Biology):
Biochemical mechanisms involved in plant hormone signalling;
genome mapping.


Warren Ewens (Biology):
Mathematical population genetics.

Ellis Golub (Biochemistry, Dental School):
The relationship between protein sequence, structure and 
function.

Greg Guild (Biology):
Sequential activation of ecdysone-regulated genes in 
Drosophila development; mechanisms of 
transcriptional regulation.

Aravind Joshi (Computer and Information Science):
Problems that overlap computer science and linguistics.

Sampath Kannan (Computer and Information Science):
algorithms in computational biology, complexity theory,
randomization and computation.

Haig Kazazian (Genetics):
The analysis of mutational mechanisms in humans.

Steve Liebhaber (Genetics):
DNA structure-function relationships.

Mitch Marcus (Computer and Information Science):
Natural language processing.

Max Mintz (Computer and Information Science):
Decision making under uncertainty.

Chris Overton (Genetics):
Genome informatics and biological databases.

Peter Petraitis (Biology):
Community ecology of marine ecosystems:
theoretical ecology.

David Roos (Biology):
Molecular genetics and cell biology of protozoan parasites; Host-pathogen 
interactions; Eukaryotic evolution.

David Searls (Genetics):
Linguistics of biological sequences; genome informatics.

Neil Shubin (Biology):
Evolution of developmental patterns; origins of the vertebrate limb; 
Comparative molecular and paleontological phylogenies.

Eero Simoncelli (Computer and Information Science):
Representation and analysis of visual imagery: 
distributed parallel representation and computation.

Rich Spielman (Genetics):
Genetics of susceptibility to complex human diseases.

Chris Stoeckert (Children's Hospital of Philadelphia):
Understanding the regulation of fetal and adult globin genes in human 
adults.

Santosh Venkatesh (Electrical Engineering):
computational learning theory.

Tandy Warnow (Computer and Information Science):
combinatorial and graph-theoretic algorithms for 
evolutionary tree construction.

All applicants (predoctoral and postdoctoral) to this interdisciplinary 
program should contact:



           Computational Biology Training Program
           Department of Biology
           University of Pennsylvania
           Philadelphia, PA 19104-6018
           compbio@central.cis.upenn.edu

Admission to the predoctoral program requires acceptance
into a regular PhD program at the University 
of Pennsylvania. For application materials
contact one of the following:



Graduate Admissions
Department of Computer and Information Science
200 S. 33rd Street
University of Pennsylvania, Philadelphia PA 19104-6389


Graduate Admissions 
Department of Biology
University of Pennsylvania
Philadelphia, PA 19104-6018



Biomedical Graduate Studies (Molecular Biology)
240 John Morgan
University of Pennsylvania
Philadelphia, PA 19104-6064






****************************************************************************
Please return this form with the information filled out to 
          Computational Biology Training Program
          Department of Biology
          University of Pennsylvania
          Philadelphia PA 19104-6018
          compbio@central.cis.upenn.edu



                  Computational Biology at Penn
                          Application

Name

U.S. Citizen, Permanent Resident, or other?

Address

Email

Fax

Phone

Degree(s)

Coursework (undergraduate and graduate) in Mathematics, Computer Science,
        Probability and Statistics:

Coursework (undergraduate and graduate) in Biology, Molecular Genetics, etc.:


Coursework (undergraduate and graduate) in other relevant disciplines:

Undergraduate GPA and institution

Graduate GPA and institution

Research interests






From owner-evolution@net.bio.net Tue Dec 17 22:00:00 1996
Path: biosci!rutgers!gatech!csulb.edu!hammer.uoregon.edu!news.uoregon.edu!newsfeed.orst.edu!news.orst.edu!gus.FSL.ORST.EDU!krutovsk
From: krutovsk@fsl.orst.edu (Konstantin Krutovskii)
Newsgroups: bionet.molbio.evolution
Subject: GRADUATE ASSISTANTSHIPS - PLANT/TREE MOLECULAR GENETICS
Date: Tue, 17 Dec 1996 21:12:29
Organization: Forestry Sciences Lab
Lines: 44
Message-ID: <krutovsk.150.001535E6@fsl.orst.edu>
NNTP-Posting-Host: gus.fsl.orst.edu
X-Newsreader: Trumpet for Windows [Version 1.0 Rev A]

GRADUATE ASSISTANTSHIPS - PLANT/TREE MOLECULAR GENETICS

Two Graduate Research Assistantships are available in the Department of Forest 
Science at Oregon State University beginning July 1997.  Students must apply and
be accepted into either the Department of Forest Science, the Molecular and 
Cellular Biology Program, or the Genetics Program at OSU.  Doctoral students are
preferred, but outstanding students who lack a Masters are also encouraged to 
apply.  Students should have excellent grades and GRE scores; strong course 
and/or research experience in molecular genetics; and demonstrated ability to 
write and speak English well.  Three to five years of half-time support, and 
tuition remission, are available subject to adequate performance in research and
coursework.  

Students may work on a variety of topics related to gene identification, genetic
engineering, and genome mapping.  Most work in the laboratory deals with poplars
and Douglas-fir.   Students may develop other areas for research, however, 
current topics of interest include:

- Isolation and manipulation of floral homeotic genes for engineering of 
reproductive development

-Effects of matrix attachment regions on gene silencing in transgenic poplars

-Population genetic studies of gene diversity and gene flow using microsatellite
markers

-Genetic engineering of systems for inducible sterility/fertility 

-Molecular engineering of genotype independent transformation systems

-Ecophysiological consequences of genetic engineering for lignin modification

-Development of microsatellite marker-maps and use for QTL analysis 


For information or an application form (specify department), contact Steve 
Strauss, Dept. of Forest Science, Oregon State University, Corvallis, OR 
97331-7501, fax 541 737 1393, phone -6578, strauss@FSL.orst.edu







From owner-evolution@net.bio.net Tue Dec 17 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!online.no!sn.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!news-peer.gsl.net!news.gsl.net!portc01.blue.aol.com!newsstand.cit.cornell.edu!news.acsu.buffalo.edu!dsinc!netnews.upenn.edu!central.cis.upenn.edu!tandy
From: tandy@central.cis.upenn.edu (Tandy Warnow)
Newsgroups: bionet.molbio.evolution
Subject: Programmer sought
Date: 17 Dec 1996 22:19:38 GMT
Organization: University of Pennsylvania
Lines: 76
Message-ID: <59769q$nn7@netnews.upenn.edu>
NNTP-Posting-Host: central.cis.upenn.edu

Newsgroups: comp.theory
Subject: algorithms programmer sought
Summary: 
Expires: 
Sender: 
Followup-To: 
Distribution: 
Organization: University of Pennsylvania
Keywords: 
Cc: 

         ALGORITHMS PROGRAMMER POSITIION
     for Evolutionary Tree Construction Methods

          at the University of Pennsylvania
      Department of Computer and Information Science
            Philadelphia PA 19104-6389

 
I have a position available for a programmer who is
highly trained in discrete algorithms. The position will involve
algorithm design, implementation, experimental performance 
analysis, and analysis of hard biological data sets
(such as HIV sequences or the mitochondrial DNA data for
the African-Eve hypothesis).  The project is to design and
test new methods for inferring evolutionary history
in Biology.

I am seeking a programmer who is well-trained theoretically
with a solid background in Discrete Algorithms.  The undergraduate
major should be either Mathematics or Computer Science, with
significant coursework in programming languages, algorithms, and
data structures.  The language we will implement the methods
in will be C.

Applicants with advanced degrees (Masters and/or PhD) are
also sought for positions which may include experimental 
work in algorithms and implementation.

 
The research team includes Scott Nettles, an experimental
computer scientist; Ken Rice, a systematic biologist, and
Tandy Warnow, a theoretical computer scientist.  The
University of Pennsylvania has an active research program
in Discrete Mathematics and Theoretical Computer 
Science, and an NSF-funded training program in Computational
Biology.  We are also located close to other universities
and research laboratories, and are 1.5 hours south of DIMACS.

The position is available now and will remain open until filled.
Please send:

          list of courses taken in computer science and
               mathematics, along with grades
          names and phone numbers of people willing to
               write reference letters
          vita and list of publications, if applicable
           
    to:   tandy@central.cis.upenn.edu
 
       or Tandy Warnow
          200 S. 33rd Street
          Department of Computer and Information Science
          University of Pennsylvania
          Philadelphia PA 19104-6389
    

Students considering applying for the PhD program in
Computer Science who are interested in theoretical computer
science and/or computational biology are also encouraged to 
apply. For information on how to apply to Penn's PhD program
in Computer and Information Science, contact Mike Felker
at mfelker@central.cis.upenn.edu.


Tandy Warnow

From owner-evolution@net.bio.net Tue Dec 17 22:00:00 1996
Path: biosci!agate!spool.mu.edu!newspump.sol.net!howland.erols.net!dciteleport.com!newsfeed.internetmci.com!compuserve.com!news.production.compuserve.com!news
From: Bob Obar <102063.2640@CompuServe.COM>
Newsgroups: bionet.cellbiol,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.genbank,bionet.molbio.proteins
Subject: Alu sequences within dbEST entries
Date: 18 Dec 1996 12:50:36 GMT
Organization: Matritech, Inc.
Lines: 17
Message-ID: <598pas$1s2$1@mhafc.production.compuserve.com>
Xref: biosci bionet.cellbiol:6233 bionet.molbio.evolution:5444 bionet.molbio.gdb:549 bionet.molbio.genbank:2444 bionet.molbio.proteins:9576

  Several of the EST sequences I've been analyzing contain Alu 
sequences (specifically, the warning that shows up in the Definition
field is something like "similar to contains Alu repetitive 
element;contains element L1 repetitive element."

  Can anyone explain: 
  A) Why these sequences should be present AT AL in ESTs, which are 
supposed to represent cDNAs; or 
  B) What to do about them when aligning the ESTs and e.g. trying to
make contigs from them?  
  I'd like to just ignore them when analyzing the DNA they're fused 
to, but is this acceptable practice?  Is there any meaning in the 
presence of these sequences in some cDNAs but not others?
  Any help by email or posting would be greatly appreciated.

-- Bob Obar
102063.2640@compuserve.com

From owner-evolution@net.bio.net Wed Dec 18 22:00:00 1996
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From: Jeffrey Sonnentag <sonnjef@sc.llu.edu>
Newsgroups: bionet.molbio.evolution
Subject: Iguana Symposium
Date: Thu, 19 Dec 1996 09:24:41 -0800
Organization: Loma Linda University Medical Center
Lines: 49
Message-ID: <32B97A59.71A@sc.llu.edu>
Reply-To: sonnjef@sc.llu.edu
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MEETING ANNOUNCEMENT

                       IGUANA SYMPOSIUM

To be held at the 77th Annual Meeting of the American Society of
Ichthyologists and Herpetologists, 26 June - 2 July 1997, at the
University of Washington, Seattle, WA.  The Herpetologists League (HL),
the Society for the Study of Amphibians and Reptiles (SSAR), the Early
Life History (ELH) Section of the American Fisheries Society (AFS), the
American Elasmobranch Society (AES), and the Gilbert Ichthyological
Society (GIS) will all meet jointly with ASIH (See
http://artedi.fish.washington.edu/asih/asih97.html).


                       Symposium Title

      EVOLUTION, ECOLOGY AND CONSERVATION OF IGUANAS


Ronald L. Carter and William K. Hayes, Co-organizers

======================================================================

Interest in the biology of iguanas has greatly increased in the last few
years. A list of current iguana researchers is in excess of sixty
individuals.  Many iguana specialists have expressed the desire to
dialogue with the full community of investigators who are working with
iguanas in various disciplines such as systematics, evolution, behavior,
physiology and ecology.  It has been 14 years since publication of the
important book "Iguanas of the World", edited by Gordon M. Burghardt and
A. Stanley Rand.  Once again it appears timely to amass a new corpus of
data for publication.  New data on the biology of iguanas are being
collected and much of these data are yet unpublished.  The purpose of
this symposium is to facilitate communication of ideas, the networking
of iguana researchers and ultimately a better understanding of iguana
biology and the conservation of these marvelous organisms.

For additional information contact Ronald L. Carter or William K. Hayes,
Department of Natural Sciences, Loma Linda University, Loma Linda, CA
92350 USA; telephone (909) 824-4530; or send E-mail to
rcarter@ccmail.llu.edu or whayes@ccmail.llu.edu

======================================================================

If you are interested in presenting a paper, you may wish to inform us
soon of your desire and provide a tentative title or topic.  We would
like to create a list of tentative speakers and add it to the ASIH
meeting announcement on the internet, as other symposia organizers have
already done.

From owner-evolution@net.bio.net Wed Dec 18 22:00:00 1996
Path: biosci!daresbury!nntp-trd.UNINETT.no!nntp.uio.no!www.nntp.primenet.com!nntp.primenet.com!howland.erols.net!math.ohio-state.edu!jussieu.fr!fdn.fr!med.univ-tours.fr!univ-angers.fr!ciril.fr!cnusc.fr!univ-lyon1.fr!news
From: duret@misa.univ-lyon1.fr (Laurent Duret)
Newsgroups: bionet.cellbiol,bionet.molbio.evolution,bionet.molbio.gdb,bionet.molbio.genbank,bionet.molbio.proteins
Subject: Re: Alu sequences within dbEST entries
Date: 19 Dec 1996 08:59:35 GMT
Organization: Universite Claude Bernard - Lyon 1
Lines: 73
Message-ID: <59b05n$j0@tempo.univ-lyon1.fr>
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Xref: biosci bionet.cellbiol:6243 bionet.molbio.evolution:5446 bionet.molbio.gdb:552 bionet.molbio.genbank:2446 bionet.molbio.proteins:9581

In article <598pas$1s2$1@mhafc.production.compuserve.com>, Bob Obar <102063.2640@CompuServe.COM> writes:
>  Several of the EST sequences I've been analyzing contain Alu 
>sequences (specifically, the warning that shows up in the Definition
>field is something like "similar to contains Alu repetitive 
>element;contains element L1 repetitive element."
>
>  Can anyone explain: 
>  A) Why these sequences should be present AT AL in ESTs, which are 
>supposed to represent cDNAs;  

[...]
> Is there any meaning in the 
>presence of these sequences in some cDNAs but not others?


Repeats such as Alu have been found inserted not only in intergenic
sequences, but also within genes: within introns, 5'UTRs, 3'UTRs
and even - albeit less frequently - in coding regions. 
A simple (simplistic) model of selection can explain the distribution 
of repeated elements in a genome: repeated elements may insert themselves 
anywhere, but insertions that disrupt an essential function are
eliminated by selection. In other words, any insertion that does not
disrupt an essential function can be tolerated and fixed in the
population. This model can explain why repeated
elements are more common in intergenic regions or introns than
in UTRs and even more than in coding regions. Hence if you find
an Alu repeat within a gene, then it probably just means that
it does not affect the function of this gene (although there are also a
few cases where repeated elements have been shown to be involved
in the regulation of a gene... evolution is opportunistic:
if an insertion appears be useful then it may be positively selected).
Eventually, it is not surprising to find Alu repeats within
some mRNAs. 

Moreover, EST sequences do not all correspond to functional mRNAs.
Any polyadenylated transcript can be found among ESTs (e.g. it is
likely that some pseudogenes are still transcribed). So it is
not surprising to find "junk transcripts" (by analogy to junk DNA)
among EST sequences.




>  B) What to do about them when aligning the ESTs and e.g. trying to
>make contigs from them?  

For similarity searches (BLAST, FASTA, ...), you can use the XBLAST
program to mask Alu (or other) repeats within sequences and thus
avoid the spurious matches with the thousands of Alu-containing
sequences. XBLAST is available by anonymous FTP at ncbi.nlm.nih.gov in 
/pub/jmc/xblast. For a discussion of this problem see Claverie & States
1993  Comput. Chem. 17:191-201 or Altschul et al. 1994 Nature 
genet. 6:119-129

This solution could be suitable for contiging if the repeat is
not too long. Otherwise I don't know if there is any
simple solution.


Hope this helps,

Laurent Duret

__________________________________________________________________________
Laurent Duret                           
Laboratoire BGBP - UMR CNRS 5558     Phone  : +33 472 44 80 00  p.34 39
Universite Claude Bernard - Lyon 1   FAX    : +33 478 89 27 19
43 Bd du 11 Novembre 1918            e-mail : duret@biomserv.univ-lyon1.fr
F-69622 Villeurbanne Cedex           ========================
France
__________________________________________________________________________



From owner-evolution@net.bio.net Fri Dec 20 22:00:00 1996
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From: mkolkkal@cc.Helsinki.FI (Mikko J Kolkkala)
Newsgroups: bionet.molbio.evolution
Subject: Re: Why aren't rabbits green?
Date: 21 Dec 1996 18:00:48 GMT
Organization: University of Helsinki
Lines: 19
Message-ID: <59h8kg$53i@oravannahka.Helsinki.FI>
References: <5417h1$32ag@uvaix3e1.comp.UVic.CA> <Pine.HPP.3.91.961020034223.28734A-100000@csws12.ic.sunysb.edu>
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Grace K Hsu (ghsu@ic.sunysb.edu) wrote:
: > 
: > Given the fact that rabbits are rather defenceless prey animals that
: > spend almost all of their life outside the warren eating against a
: > green background, why haven't they evolved to be green?

Partial explanation could be the poor ability of mammalian predators to see
colours - grass is not green for them! 

On the other hand some avian predators have excellent colour vision, so
green fur _could_ be useful for rabbits.


--
 (:  Mikko Kolkkala                   :) (:  Department of Biosciences, :)
 :)  email: mkolkkal@helsinki.fi      (: :)  Division of Genetics       (:
 (:  tel +358-9-70859115              :) (:  P.O. box 56, FIN-00014     :) 
 :)  http://www.helsinki.fi/~mkolkkal (: :)  University of Helsinki     (:
 			

From owner-evolution@net.bio.net Fri Dec 20 22:00:00 1996
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From: Jan Kim <kim@violet.mpiz-koeln.mpg.de>
Newsgroups: bionet.info-theory,bionet.molbio.evolution
Subject: CFP: German Workshop on Artificial Life
Date: 20 Dec 1996 23:40:33 GMT
Organization: MPI fuer Zuechtungsforschung
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Xref: biosci bionet.info-theory:4445 bionet.molbio.evolution:5448

Call for papers and participation for the

SECOND GERMAN WORKSHOP ON ARTIFICIAL LIFE (GWAL'97)

Dortmund, April 17-18, 1997.


Intention

Artificial Life (AL) is an interdisciplinary field of science that is
focused on abstracting the essential features and dynamics of living
systems in order to create models of these systems in "artificial"
media, i.e.  media that are man-made and different from the media in
which the systems live in Nature. The major goals of such activities
are:

    * To open up new pathways for investigating and understanding
      living systems.
    * To make complex features of living systems available for the
      design of artificial systems, such as computer programs and
      robots.
    * To contribute to the building of formal theories describing
      living systems.

Relevant contributions to Artificial Life have originated from
mathematics, physics, information and computer sciences, biosciences,
medicine, psychology, social sciences, and many other disciplines.
While the emergence of Artificial Life as a scientific community took
place about a decade ago, opportunities for scientists who use AL
approaches in their work to communicate with their interdisciplinary
colleagues are still rather scarce. The German Workshop on Artificial
is intended to bring together scientists from Germany and other
countries who are pursuing Artificial Life projects. Equally
importantly, the workshop is intended as a forum for scientists who
would like to get into contact with the Artificial Life community.


Workshop Format

The GWAL is intended to mediate lively discussions and exchange of
ideas in addition to providing an impression of AL related activities
in Germany and other countries. To allow participants to get a survey
of the diversity of AL, and to provide ample opportunity for individual
discussions, poster sessions and demonstrations of Artificial Life
systems will be the main element of the GWAL. Furthermore, there will
be workgroup sessions. In the workgroups, subfields of AL will be
introduced by presenting substantial work from the area, thus providing
a starting point for a thorough and in-depth discussion of the subject
by all participants in the workgroup.


Submissions

A. Submissions for talks and posters

Submissions are invited for oral and poster sessions. They should
be sent as extended abstracts no longer than two pages of text and
two pages of accompanying figures. Submissions are invited on all
issues pertaining to artificially living and life-like systems,
including the following topics:

    * Modelling biological processes and living systems, such as
      evolution, ecology, morphogenesis, immune systems, neuronal
      systems, perception and pattern recognition, intelligence,
      adaptive behaviour, learning, and others.
    * Emergence of biological complexity.
    * Dynamics of information in living and life-like systems.
    * Self-organization in living and life-like systems (e.g. swarms,
      hypercycles, multicellular systems, artificial multi-agent systems).
    * Applications of principles and features of living systems, such
      as intelligence, self-organization, evolution, adaptation,
      learning, for the design of artificial systems and technical
      solutions such as robots, computer programs, and hardware.
    * Philosophical and ethical issues.
    * Other issues relevant to Artificial Life.

In addition to reporting research work, submissions may describe research
projects or discuss interesting open questions. Submissions will be
accepted either for talks or for posters.
    Communication about Artificial Life systems can often be strongly
improved by demonstrations, therefore, all presentations may be
accompanied by demonstrations (e.g. of computer programs or robots).
Arrangements regarding technical equipment necessary for demonstrations
can be made with the local workshop organizers.


B. Proposals for workgroups

Workgroups are intended to allow  in-depth discussions of
specific subfields of Artificial Life. Workgroups will be organized by
groups of at least two scientists who are willing to give an introductory
survey of the subject. Workgroup organizers should focus on describing
the essence of the subfield, i.e. the fundamental motivations, major
approaches and achievements, open questions etc. to the other
participants.
    Proposals for workgroups should be submitted as descriptions of
up to three pages. Descriptions should include:

    * An outline of the subject of the proposed workgroup.
    * An indication what audience would be interested in participating
      in the proposed workgroup.
    * Some references to substantial contributions that have been made
      in the subfield.

All submissions should be sent to:

    German Workshop on Artificial Life
    Lehrstuhl fuer Systemanalyse (LS 11)
    Fachbereich Informatik
    Universitaet Dortmund
    D-44221 Dortmund

    email: gwal@ls11.informatik.uni-dortmund.de


Organization

The GWAL is organized by the Lehrstuhl fuer Systemanalyse,
Institut fuer Informatik, Universitaet Dortmund (Chair of Systems
Analysis, Dept. of Computer Science, University of Dortmund). 
The GWAL is co-organized by the Fachgruppe 4.0.2
"Informatik in den Biowissenschaften" of the Gesellschaft fuer
Informatik (GI) and by the Arbeitskreis "Artificial Life" of
the GI. The program committee for the GWAL is:

    Wolfgang Banzhaf, Dortmund
    Wilfried Brauer, Muenchen
    Thomas Christaller, Sankt Augustin
    Kerstin Dautenhahn, Bruessel
    Jochen Heistermann, Muenchen
    Ralf Hofestaedt, Magdeburg
    Frieder Lohnert, Berlin
    Hanspeter A. Mailot, Tuebingen
    Christian Mueller-Schloer, Hannover

The organizing committee for the GWAL is:

    Wolfgang Banzhaf, Dortmund
    Peter Dittrich, Dortmund
    Jan T. Kim, Koeln
    Hilmar Rauhe, Dortmund


Conference language

Submissions may be written in English or in German. We encourage
submitters to prepare their communications in English (so that
participants from other countries can follow their presentations).


Important dates:

Deadline:      February 14., 1997
Notification:  March 14., 1997 
Workshop:      April 17.-18., 1997


Location

The GWAL will be held in Haus Bommerholz, a guest house run by the
University of Dortmund. The address is:

    Haus Bommerholz
    Bommerholzer Str. 60
    58456 Witten-Bommerholz
    Tel. +49-(0)2302 39 60
    Fax. +49-(0)2302 39 63 20

The number of participants of the GWAL is limited to 100. Haus Bommerholz
can provide accomodation for up to 50 participants. Rooms are available
on a first come, first serve basis. Prices for accomodation in  Haus
Bommerholz for the two workshop days are 

                double room (*)  single room (*)     no room (**)
--------------------------------------------------------------------
regular            178,-           198,-              112,-
university staff   152,-           165,-               94,-
Uni DO staff       104,-           123,-               76,-
student             66,-            72,-               46,-

(**) includes: usage of seminar and recreation  facilities for 2 days, 
               2 (warm) lunches, 4 coffee breakes
(*) includes: (**) and 1 breakfast, 1 dinner, bed for one night (17. to 18.)
The rooms are hotel-like and comfortable (bathroom, shower, TV, phone).

If you like to stay additional days (e.g. 16. to 17. Apr.)
the prices for a room incl. breakfast are:

                  double room          single room 
--------------------------------------------------------------------
regular                 61,-               104,-
university staff  about 55,-          about 90,-
student                 25,-                31,- 

Prices in DM (german mark) without guaranty of correctness. 
Payable on site in bar or via EC card (no credit cards).

In addition to the cost for accomodation we may have to
collect a small fee covering our expenses for 
advertising, workshop handouts etc.
 


Registration and further information.

If you are interested in participating in the GWAL, please pre-register
by sending email to gwal@ls11.informatik.uni-dortmund.de as soon as
possible. Please use the form attached to this document. You will then
receive further information by email. Information regarding registration
for the GWAL will also be announced in the WWW on the GWAL homepage:

    http://ls11-www.informatik.uni-dortmund.de/GWAL/

For any further information, please feel free to contact the GWAL organizers:

    German Workshop on Artificial Life
    Lehrstuhl fuer Systemanalyse (LS 11)
    Fachbereich Informatik
    Universitaet Dortmund
    D-44221 Dortmund

    email: gwal@ls11.informatik.uni-dortmund.de

----------------8<-------------- BEGIN FORM -------------8<-------------

                                 GWAL '97
                   2. German Workshop on Artificial Life


Yes, I am interested in the participation of the GWAL '97. Please send
me more information.



Surname:         ___________________________  First name: ______________

Title:           o   Prof.    o Dr.    o Mrs.     o Mr.

Institution/
Company:         _______________________________________________________
         
                 _______________________________________________________

Mailing Address: _______________________________________________________

Postal Code:     _______________________________________________________

City:            _______________________________________________________

Country:         _______________________________________________________

Phone:           _______________________________________________________

Fax:             _______________________________________________________

E-Mail:          _______________________________________________________

WWW(URL):        _______________________________________________________


Planed arrival:     o 16. April   o 17. April   o 18. April

Planed departure:                 o 17. April   o 18. April   o 19. April

Planed accomodation:    o Haus Bommerholz       o other

Planed contribution:    o talk     o poster    o work group   o demo   o none


----------------8<--------------- END FORM -----------------8<----------------


From owner-evolution@net.bio.net Sun Dec 22 22:00:00 1996
Path: biosci!unq.edu.ar!gustavo
From: gus