From owner-molec-model@net.bio.net Thu Apr 06 23:00:00 1995 Path: biosci!daresbury!bioftp.unibas.ch!news.vub.ac.be!idefix.CS.kuleuven.ac.be!Belgium.EU.net!EU.net!howland.reston.ans.net!quagga.ru.ac.za!inet.up.ac.za!rincewind.up.ac.za!fourie From: fourie@ccnet.up.ac.za (Fourie Joubert) Newsgroups: bionet.molec-model Subject: Raster3D on Solaris 2.3? Date: Fri, 7 Apr 1995 07:49:15 GMT Organization: University of Pretoria Lines: 19 Message-ID: NNTP-Posting-Host: rincewind.up.ac.za Hi Has anyone compiled Raster3D on Solaris? I have compiled it on Linux without problems, and I am really impressed but it is a little slow on my 486. I would prefer to run it on our Sparc1000, but can not get it to compile... Any help would be sincerely appreciated? __________________________________________________________________________ _/_/_/_/ _/_/_/_/_/ Fourie Joubert _/ _/ Department of Biochemistry _/ _/ University of Pretoria _/_/_/_/ _/ South Africa _/ _/ fourie@ccnet.up.ac.za _/ _/_/_/_/ http://suntiger.ee.up.ac.za/biodocs/home.html __________________________________________________________________________ From owner-molec-model@net.bio.net Sun Apr 09 23:00:00 1995 Path: biosci!adam.cc.sunysb.edu!news.sprintlink.net!howland.reston.ans.net!news2.near.net!news3.near.net!yale!usenet From: abonvin@volta.csb.yale.edu ("Alexandre Bonvin") Newsgroups: bionet.molec-model Subject: X-PLOR www pages Date: 10 Apr 1995 17:48:36 GMT Organization: Yale University, Department of Computer Science, New Haven, CT Lines: 16 Message-ID: <3mbr1k$ij3@babyblue.cs.yale.edu> NNTP-Posting-Host: volta.csb.yale.edu Dear netters, Xplor has now a www home page featuring the X-PLOR manual and tutorial files on-line. The address is: http://pauli.csb.yale.edu Alexandre ========================================================================== | Alexandre Bonvin PhD | Phone: (203) 432-5066 | | Mol. Biophys. & Biochemistry | Fax: (203) 432-6946 | | Yale University, PO Box 208114 | Email: abonvin@laplace.csb.yale.edu | | New Haven CT 06511, USA | | ========================================================================== From owner-molec-model@net.bio.net Sun Apr 09 23:00:00 1995 Path: biosci!bloom-beacon.mit.edu!usc!cs.utexas.edu!uunet!newsfeed.ACO.net!fstgds15.tu-graz.ac.at!balu.kfunigraz.ac.at!BKFUG.KFUNIGRAZ.AC.AT!KLINTSCHAR From: KLINTSCHAR@BKFUG.KFUNIGRAZ.AC.AT (Gerd Klintschar) Newsgroups: bionet.molec-model Subject: whre to get GRID? Date: Thu, 6 Apr 1995 22:11:12 Organization: IPC-KFUG Lines: 14 Message-ID: NNTP-Posting-Host: bpch02.kfunigraz.ac.at X-Newsreader: Trumpet for Windows [Version 1.0 Rev Final Beta #10] Dear netters! Can somebody please tell me where to get the program GRID, or/and any other program that does the same. thank you very much! Gerd ------------------------------------------------------------------------------ internet: Klintschar@bkfug.kfunigraz.ac.at voice ++43-316-380/5469, ++43-316-347694 fax ++43-316-32248 Gerd Klintschar, IPC-KFUG, Heinrichstrasse 28/5/516, 8010 Graz, Austria ------------------------------------------------------------------------------ From owner-molec-model@net.bio.net Tue Apr 11 23:00:00 1995 Path: biosci!rutgers!oitnews.harvard.edu!das-news2.harvard.edu!news2.near.net!howland.reston.ans.net!quagga.ru.ac.za!inet.up.ac.za!rincewind.up.ac.za!fourie From: fourie@ccnet.up.ac.za (Fourie Joubert) Newsgroups: bionet.molec-model Subject: To: ML Dodson Date: Wed, 12 Apr 1995 08:10:18 GMT Organization: University of Pretoria Lines: 27 Message-ID: NNTP-Posting-Host: rincewind.up.ac.za Hi Thanks for your message - your return address gets bounced as invalid from my system (bdodson@beowulf). I got raster3d to compile, but the avs2ps fortran code does not work in f77. it complains about a byte comparison in line 48 of modsubs.c. The avs file that gets created differs slightly from the one on my Linux system (1st byte), and I can not view it! Image Magick compiles happily on the Sparc, but when I try to run it I get a memory allocation error. The Sparc has 256M physical and 512M virtual memory..... Thanks for the interest and enjoy your day! __________________________________________________________________________ _/_/_/_/ _/_/_/_/_/ Fourie Joubert _/ _/ Department of Biochemistry _/ _/ University of Pretoria _/_/_/_/ _/ South Africa _/ _/ fourie@ccnet.up.ac.za _/ _/_/_/_/ http://suntiger.ee.up.ac.za/biodocs/home.html __________________________________________________________________________ From owner-molec-model@net.bio.net Wed Apr 12 23:00:00 1995 Path: biosci!biosci!not-for-mail From: andrewt@r-node.io.org (Andrew Thomas) Newsgroups: bionet.cellbiol,bionet.general,bionet.genome.chromosomes,bionet.immunology,bionet.microbiology,bionet.molbio.methds-reagnts,bionet.molbio.proteins,bionet.molec-model,bionet.mycology,bionet.plants,bionet.software,bionet.virology Subject: SURVEY - Things we'd like to see (commercial) Date: 13 Apr 1995 14:44:34 -0700 Organization: Sakura Software Inc., Mississauga, Ontario, Canada Lines: 178 Sender: biohelp@net.bio.net Distribution: world Message-ID: <3mk602$3vm@net.bio.net> NNTP-Posting-Host: net.bio.net Xref: biosci bionet.cellbiol:2072 bionet.general:14638 bionet.genome.chromosomes:541 bionet.immunology:3823 bionet.microbiology:1994 bionet.molbio.methds-reagnts:27180 bionet.molbio.proteins:4282 bionet.molec-model:320 bionet.mycology:1936 bionet.plants:6388 bionet.software:11785 bionet.virology:2246 I am posting this for a business consulting company. It is a questionnaire on the subject of lab techniques, equipment and software in the biotechnology field, with an eye toward introducing prducts into those areas where respondents feel there are weaknesses. This is your chance to complain about everything from overpriced equipment to ergonomic disfunction :-). Please send responses to one of the two addresses below: couper@magi.com andrewt@io.org Thanks in advance, Andrew Thomas ------------------------------------------------------------- April 5, 1995 ADP & Associates 42 Rideau River Lane Ottawa, Ontario K1S 0X1 TEL: (613)526-5609 email: couper@magi.com We are a business consulting company conducting a market study on behalf of a research and development group interested in expanding into biotechnology. Our client is specialized in the creation of new and innovative scientific equipment. The object of this survey is to get the direct input of the actual users of the intended technology. Our client is constantly looking to develop products that will simplify your work, save you time, improve safety and reduce your operating costs. In the questionnaire we have tried to find a balance where the questions will simultaneously cover all our respondants areas of interest and be specific enough for their particular needs. We have also tried to keep it as short as possible. Should you find that our questionnaire does not adequately address your interests, please feel free to add your comments at the end. All of your comments are valuable to us and all of your ideas have potential. Our client is capable of producing products with a varying range of complexity, from the most rudimentary test-tubes to specialized automation hardware and computer software. Should your suggestion be a starting point for an actual product, you will qualify for an idea/development bonus of $500.00 We would like to take this opportunity to thank you for your valuable input. If you have any questions or require further information please feel free to contact us at the above address or telephone number. If you would like to be kept informed of our client's product development, please print your name, address and FAX number at the bottom of the questionnaire. Yours truly, A. Douglas Palmer. -------------------------------------------------------------- Questionnaire 1. What are the three most time consuming tasks or procedures carried out in your laboratory? 2. Is equipment used in performing these tasks? [Yes/No] If so, what? If not, what would you like to see made available? 3. What types of equipment or tools for research, production or management would you like to see made available to you (not currently available on the market)? 1. 2. 3. 4. 5. What improvements (not available on the market) to your current equipment would you like to see? Please describe. 4. What types of equipment or tools, which you are not currently using, would you purchase if it were priced lower? What type of equipment or tools do you feel you are paying too much for? 5. What dangerous activities do you regularly perform? Could they be made safer with better tools or equipment? 6. What are some of the more "menial" tasks performed in your laboratory? (tasks which use up valuable personnel hours, taking away from research). 7. Could your daily operations be improved by the use of specialized computer software? [Yes/No] What should this software be capable of achieving? Please provide as much detail as you feel appropriate. Log book Data Manipulation Data Analysis Database Graphics Product interfaces Simulation and Prediction Control and Monitoring of Equipment Other 8. What are your fields of expertise? Please indicate as many as appropriate. (Please be as specific as you can). Biochemistry Microbiology Genetic Research Virology Plant Research Animal Research Medical Research Pharmaceuticals Other. 9. Is your research primarily market oriented or investigative? 10. What is the size of your laboratory (number of personnel)? 1 - 5 6 - 10 11 - 15 16 - 20 > 20 11. Which trade publications do you read? 1. 2. 3. 4 5 12. If you have any other comments or suggestions please feel free to put them here. Name: Work Address: FAX #: email address: -- Andrew Thomas - President, Sakura Software Inc. Watch for SCADALisp - Real-time control and UI language for QNX/UNIX For information, email andrewt@io.org From owner-molec-model@net.bio.net Fri Apr 14 23:00:00 1995 Path: biosci!biosci!not-for-mail From: Reece Kimball Hart Newsgroups: bionet.biology.computational,bionet.biophysics,bionet.molec-model,bionet.announce Subject: WWW SITE: Washington University in St. Louis Date: 14 Apr 1995 17:54:04 -0700 Organization: Washington University School of Medicine Lines: 17 Sender: biohelp@net.bio.net Approved: comp-bio-moderator@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Xref: biosci bionet.biology.computational:609 bionet.biophysics:859 bionet.molec-model:321 bionet.announce:1999 There is a new WWW Site for the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine in St. Louis. The URL is http://bmb.wustl.edu/ The site includes documents regarding the the department's members and their research interests, the graduate program, and research facilities. A variety of other documents pertaining to the program are planned for the near future. -- Reece Reece Kimball Hart | Internet: reece@dasher.wustl.edu Biophysics & Biochemistry, Box 8231 | WWW URL: http://dasher.wustl.edu/~reece Washington Univ. School of Medicine | Phone: (314) 362-4198 (lab) 660 South Euclid | -7183 (fax) St. Louis, Missouri 63110 (USA) | PGP public key available by finger & WWW From owner-molec-model@net.bio.net Sun Apr 16 23:00:00 1995 Path: biosci!biosci!not-for-mail From: reece@dasher.wustl.edu (Reece Hart) Newsgroups: bionet.biophysics,bionet.biology.computational,bionet.molec-model,bionet.announce Subject: WWW SITE: Washington University in St. Louis Date: 16 Apr 1995 20:27:35 -0700 Organization: Washington University School of Medicine Lines: 17 Sender: biohelp@net.bio.net Approved: bionews-moderator@net.bio.net Distribution: world Message-ID: <3mrdpk$39u@cerberus-138.wustl.edu> NNTP-Posting-Host: net.bio.net Xref: biosci bionet.biophysics:866 bionet.biology.computational:610 bionet.molec-model:322 bionet.announce:2001 There is a new WWW Site for the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine in St. Louis. The URL is http://bmb.wustl.edu/ The site includes documents regarding the the department's members and their research interests, the graduate program, and research facilities. A variety of other documents pertaining to the program are planned for the near future. -- Reece Kimball Hart | Internet: reece@dasher.wustl.edu Biophysics & Biochemistry, Box 8231 | WWW URL: http://dasher.wustl.edu/~reece Washington Univ. School of Medicine | Phone: (314) 362-4198 (lab) 660 South Euclid | -7183 (fax) St. Louis, Missouri 63110 (USA) | PGP public key available by finger & WWW From owner-molec-model@net.bio.net Mon Apr 17 23:00:00 1995 Path: biosci!bloom-beacon.mit.edu!senator-bedfellow.mit.edu!athena.mit.edu!cloutier From: cloutier@athena.mit.edu (Normand J Cloutier) Newsgroups: bionet.molec-model Subject: Would like opinion on Molec. Mod. Book Date: 18 Apr 1995 01:16:59 GMT Organization: Massachusetts Institute of Technology Lines: 28 Distribution: world Message-ID: <3mv3ub$43g@senator-bedfellow.MIT.EDU> NNTP-Posting-Host: m16-034-16.mit.edu Recently, I received a advertisement from the American Chemical Society for some of their publications. The ad for one of the books (which seems interesting to me) is given below. Since the book is not cheap, I would like to know whether anyone has seen this book and has anything to say about whether it is worth getting. While on the topic of molecular modelling books, are there any other texts which offer an introductory overview of the field. Any advice would be appreciated. Thanks in advance. Normand Cloutier cloutier@mit.edu The ad: _Molecular Modeling: From Virtual Tools to Real Problems_ Thomas F. Kumosinski and Michael N. Liebman, Editors ACS Symposium Series No. 576, 522 pages (1994) $119.95 Clothbound, ISBN 0-8412-3042-0 - Provides comprehensive theoretical and experimental methods - from molecular modeling of bioactive systems. Includes a - comprehensive review of the scope and utility of the past and - present broad array of molecular modeling techniques. Provides - detailed experimental studies to be used in conjunction with - molecular modeling to develop structure-function relationships. - Examines the forces involved in protein structure and the - interaction of these forces with cosolutes of biological and - industrial interest. From owner-molec-model@net.bio.net Mon Apr 17 23:00:00 1995 Path: biosci!WUCMD.WUSTL.EDU!stuart From: stuart@WUCMD.WUSTL.EDU (Stuart Green) Newsgroups: bionet.molec-model Subject: Journal of Computer-Aided Molecular Design Date: 18 Apr 1995 08:34:38 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 21 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net ESCOM Publishers B.V. in collaboration with the Center for Molecular Design present an experimental Web based version of the The Journal of Computer-Aided Molecular Design. http://wucmd.wustl.edu/jcamd/jcamd.html This server carries complete articles (equations, text and figures all included) from Volume 9 Number 1 (February 1995), Number 2 coming soon. We welcome your feedback regarding the presentation of such media on WWW. Any thoughts or comments please email jcamd@wucmd.wustl.edu --- Stuart M. Green stuart@wucmd.wustl.edu Center for Molecular Design Campus Box 1099 Washington University Tel 314-935-4671 St. Louis, MO 63130-4899 Fax 314-935-4979 From owner-molec-model@net.bio.net Tue Apr 18 23:00:00 1995 Path: biosci!biosci!not-for-mail From: "Alexander J. Ropelewski" Newsgroups: bionet.molec-model,bionet.molbio.proteins,bionet.cellbiol,bionet.molbio.embldatabank,bionet.molbio.genbank,bionet.molbio.evolution,bionet.announce Subject: CCL:Sequence Analysis Workshop Date: 18 Apr 1995 17:59:59 -0700 Organization: Pittsburgh Supercomputing Center, Carnegie Mellon, Pittsburgh, PA Lines: 113 Sender: biohelp@net.bio.net Approved: bionews-moderator@net.bio.net Distribution: world Message-ID: <0jZ0xSS00WB7FWtlVg@andrew.cmu.edu> NNTP-Posting-Host: net.bio.net Xref: biosci bionet.molec-model:325 bionet.molbio.proteins:4323 bionet.cellbiol:2099 bionet.molbio.embldatabank:493 bionet.molbio.genbank:2010 bionet.molbio.evolution:2702 bionet.announce:2005 NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS WORKSHOP FOR BIOMEDICAL RESEARCHERS Pittsburgh, Pennsylvania June 4-9, 1995 Pittsburgh Supercomputing Center (PSC) is again offering a five-day workshop on "Nucleic Acid and Protein Sequence Analysis," June 4-9, 1995. It is funded by a grant from the National Center for Human Genome Research of the National Institutes of Health. The workshop will familiarize biomedical researchers in applying supercomputing resources to problems of concern in macromolecular sequence analysis. Emphasis will be on alignment of and pattern extraction from multiple sequences. Participants will gain practical experience on PSC's Cray C-90 and T3D in (1) comparing and aligning sequences, (2) identifying informative patterns in a set of sequences; and (3) using extracted informative patterns to identify related sequences. Researchers will also learn several approaches to database searching and multiple sequence alignment, how to use profile analysis effectively, and how to identify patterns in their sequences. Participants are encouraged to bring sequence analysis problems from their current research. Extensive documentation will be given at the outset on the PSC computing environment as well as on the specific programs to be employed in the workshop. No prior supercomputing experience is required. Workshop leaders are Dr. Gary Churchill, Cornell University, Dr. Michael Gribskov, San Diego Supercomputing Center, and Dr. Hugh Nicholas, PSC. A limited number of grants to cover travel and hotel accommodations are available for U.S. academic participants. ALL PARTICIPANTS ARE REQUIRED TO PAY A $135 REGISTRATION FEE, IN ADVANCE, UPON ACCEPTANCE INTO THE WORKSHOP. DEADLINE FOR SUBMITTING APPLICATIONS IS FRIDAY, APRIL 21, 1995. Enrollment is lmited to 20 participants. Additional information about this workshop can be found in http://pscinfo.psc.edu/biomed/workshops95.html * * * * * PITTSBURGH SUPERCOMPUTING CENTER NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS WORKSHOP FOR BIOMEDICAL RESEARCHERS June 4-9, 1995 APPLICATION Name: ________________________________________________________________ Affiliation: ________________________________________________________________ Address: ________________________________________________________________ (Business) ________________________________________________________________ ________________________________________________________________ (Home) ________________________________________________________________ Telephone: ____________________________ ______________________________ (Business) (Home) *Social Security Number: _______-_____-_______ Citizenship:___________________ Electronic Mail Address:_______________________________________________________ Status: ___Graduate ___Post-doctoral Fellow ___Faculty ___Other (specify) In order to attend the workshop, will you need funds for travel?___ lodging?___ Please indicate specifically any special housing, transportation or dietary arrangements you will need: __________________________________________ How did you learn about this workshop:_________________________________________ REQUIREMENTS: Applicants must submit a completed application form and a cover letter. The letter should describe, in one or two paragraphs, the sequence analysis problems encountered in your research, and how participating in the workshop will enhance this research. Please include a brief statement describing your level of experience with computers. Faculty members, staff and post-docs should provide a curriculum vita. Graduate students must have a letter of recommendation from a faculty member. If you have requested travel funds, please include the cost of roundtrip air fare from your home to Pittsburgh and indicate the amount of travel funds you will need. ALL PARTICIPANTS WILL BE REQUIRED TO PAY A $135 ADVANCE REGISTRATION FEE UPON ACCEPTANCE INTO THE WORKSHOP. Please return all application materials by APRIL 21, 1995 to: Biomedical Workshop Applications Committee Pittsburgh Supercomputing Center 4400 Fifth Avenue, Suite 230C Pittsburgh, PA 15213 Direct inquiries to: Nancy Blankenstein, blankens@psc.edu or 412/268-4960. *Disclosure of Social Security Number is voluntary. PSC does not discriminate on the basis of race, color, religion, sex, age, creed, national or ethnic origin, or handicap. From owner-molec-model@net.bio.net Tue Apr 18 23:00:00 1995 Path: biosci!adam.cc.sunysb.edu!news.sprintlink.net!pipex!uunet!in1.uu.net!news.nyc.pipeline.com!news.intercon.com!udel!ssnet.com!dmpcfc!David_H._Rominger From: David_H._Rominger@dmpcfc.com (David H. Rominger) Reply-To: David_H._Rominger@dmpcfc.com Newsgroups: bionet.molec-model Distribution: world Subject: Protein textbook Date: 19 Apr 1995 07:39:42 GMT Message-ID: <4261736446.81099551@dmpcfc.com> Organization: DMPC.PCS Lines: 16 Hello, Is anyone familiar with the book " The Structure and Action of Proteins" by: Dickerson and Geis? It has a copywrite of 1969. Is there a more current edition? Or, is there a better more up-to-date book with a similar coverage of this material. In other words a comparable or superior text that is current. Dave ------------------------------------------------------------------------- All comments/opinions in this message are solely those of the sender, and do not necessarily reflect the views of the employer. ------------------------------------------------------------------------- From owner-molec-model@net.bio.net Wed Apr 19 23:00:00 1995 Path: biosci!biosci!not-for-mail From: "Alexander J. Ropelewski" Newsgroups: bionet.announce,bionet.molec-model,bionet.molbio.proteins,bionet.cellbiol Subject: CCL:Methods of Molecular Mechanics and Dynamics of Biopolymers workshop Date: 19 Apr 1995 19:21:33 -0700 Organization: Pittsburgh Supercomputing Center, Carnegie Mellon, Pittsburgh, PA Lines: 107 Sender: biohelp@net.bio.net Approved: bionews-moderator@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Xref: biosci bionet.announce:2010 bionet.molec-model:327 bionet.molbio.proteins:4337 bionet.cellbiol:2108 "METHODS OF MOLECULAR MECHANICS AND DYNAMICS OF BIOPOLYMERS" WORKSHOP Pittsburgh Supercomputing Center August 16-19, 1995 The Pittsburgh Supercomputing Center (PSC) is hosting a workshop on "Methods of Molecular Mechanics and Dynamics of Biopolymers," August 16-19, 1995. The workshop will familiarize biomedical researchers with computational methods and provide practice in applying supercomputing resources to problems of concern in molecular mechanics. Practical experience on our supercomputers will be gained in the application to: (1) the theory and practice of molecular mechanics and dynamics; (2) the development and refinement of molecular mechanics force fields; (3) the problem of conformation mapping and analysis of polypeptide structures, including the refinement of structure from measured NMR data; and (4) computation of interaction energies and free energies for protein-drug interactions and conformational thermodynamics. Workshop leaders are Dr. Charles L. Brooks III, The Scripps Research Institute and Dr. Alexander D. MacKerell Jr., University of Maryland at Baltimore. The worskhop will consist of lectures and extensive hands-on sessions. General aspects of molecular mechanics software will be discussed and a number of packages are available for use at the PSC. However, the programs CHARMM and QUANTA will be utilized most extensively in demonstrations. Hands-on sessions will be emphasized. Participants will be able to work on the examples provided or on their own experimental data. No prior supercomputing experience is necessary. This workshop is funded by a grant from the Biomedical Research Technology Program, National Center for Research Resources, National Institutes of Health. TRAVEL, MEALS AND HOTEL ACCOMMODATIONS FOR RESEARCHERS AFFILIATED WITH U.S. ACADEMIC INSTITUTIONS ARE SUPPORTED BY THIS GRANT. Enrollment is limited to 20. An application form is included. Deadline for applications is: June 22, 1995. Please direct inquires or send the following application form to blankens@psc.edu. Additional information about this workshop can be found in http://pscinfo.psc.edu/biomed/workshops95.html PITTSBURGH SUPERCOMPUTING CENTER BIOMEDICAL INITIATIVE ************************************** August 16-19, 1995 APPLICATION Name:________________________________________________________________________ Affiliation:_________________________________________________________________ Address:_____________________________________________________________________ (Business) _____________________________________________________________________________ ____________________________________________________________________________ (Home) ____________________________________________________________________________ Telephone: ____________________ ______________________ (Business) (Home) *Social Security Number: _______-_____-_______ Citizenship: ____________ Electronic Mail Address:____________________________________________________ Status: ___Graduate ___Post-doctoral Fellow ___Faculty ___Other (specify) Please indicate specifically any special housing, transportation or dietary arrangements you will need: _______________________________________________ How did you learn about this workshop? _____________________________________ REQUIREMENTS: Applicants must submit a completed application form and a cover letter. The letter should describe, in one or two paragraphs, your current research and how participating in the workshop will enhance this research. Please include a brief statement describing your level of experience with computers. Faculty members, staff and post-docs should provide a curriculum vita. Graduate students must have a letter of recommendation from a faculty member. Please return all application materials by June 22, 1995 to: Biomedical Workshop Applications Committee Pittsburgh Supercomputing Center 4400 Fifth Avenue, Suite 230C Pittsburgh, PA 15213 Direct inquiries to: Nancy Blankenstein, blankens@psc.edu or 412/268-4960. *Disclosure of Social Security Number is voluntary. PSC does not discriminate on the basis of race, color, religion, sex, age, creed, national or ethnic origin, or handicap. From owner-molec-model@net.bio.net Wed Apr 19 23:00:00 1995 Newsgroups: bionet.molec-model Path: biosci!ns1.faseb.org!darwin.sura.net!nih-csl!rvenable From: rvenable@deimos.cber.nih.gov (Rick Venable) Subject: Re: Protein textbook Message-ID: <1995Apr20.040311.19906@alw.nih.gov> Sender: postman@alw.nih.gov (AMDS Postmaster) Nntp-Posting-Host: deimos.cber.nih.gov Organization: FDA/CBER Biophysics Lab X-Newsreader: TIN [version 1.2 PL2] References: <4261736446.81099551@dmpcfc.com> Date: Thu, 20 Apr 1995 04:03:11 GMT Lines: 16 On 19 Apr 1995 07:39:42 GMT David H. Rominger pontificated: > Is anyone familiar with the book " The Structure and Action of Proteins" by: > Dickerson and Geis? > It has a copywrite of 1969. Is there a more current edition? Or, is there a > better more up-to-date book with a similar coverage of this material. In > other words a comparable or superior text that is current. I've gone thru Dickerson and Geis a couple times in the past, and I think a suitable more up to date replacement is a similar book by Branden and Toose (I hope I've spelled the names correctly). -- Rick Venable =====\ |=| "Eschew Obfuscation" FDA/CBER Biophysics Lab |____/ |=| Bethesda, MD U.S.A. | \ / |=| / Not an official statement \ rvenable@deimos.cber.nih.gov \/ |=| \ or position of the FDA. / From owner-molec-model@net.bio.net Wed Apr 19 23:00:00 1995 Path: biosci!bloom-beacon.mit.edu!gatech!swrinde!pipex!oleane!jussieu.fr!univ-lyon1.fr!swidir.switch.ch!scsing.switch.ch!elna.ethz.ch!igc.chem!ana From: ana@igc.chem.ethz.ch (Alain Nanzer) Newsgroups: bionet.molec-model Subject: Re: Protein textbook Date: 20 Apr 1995 10:54:49 GMT Organization: Computational Chemistry, ETH, Zuerich Lines: 12 Sender: ana@sylvaner (Alain Nanzer) Message-ID: <3n5ehp$m69@elna.ethz.ch> References: <4261736446.81099551@dmpcfc.com> <1995Apr20.040311.19906@alw.nih.gov> NNTP-Posting-Host: sylvaner.ethz.ch Not bad is: >> Introduction to Protein Structure by Carl Branden and John Tooze Garland Publishing, Inc. New York and London, 1991 ISBN 0-8153-0344-0 -alain From owner-molec-model@net.bio.net Thu Apr 20 23:00:00 1995 Path: biosci!agate!news.mindlink.net!news.bc.net!unixg.ubc.ca!laue.biochem.ubc.ca!ywchen From: ywchen@laue.biochem.ubc.ca (Y. W. Chen) Newsgroups: bionet.molec-model Subject: protein-protein docking program? Date: 21 Apr 1995 16:27:33 GMT Organization: University of British Columbia, Vancouver, B.C., Canada Lines: 17 Distribution: world Message-ID: <3n8mdl$8j1@nntp.ucs.ubc.ca> NNTP-Posting-Host: laue.biochem.ubc.ca Dear all, I am studying the interaction of a protein enzyme with a protein substrate. From mutation studies, I know roughly which region of the enzyme interacts with which region of the substrate. Can someone recommend a program to predict the docking of these 2 proteins? It would be best if the results can be visualized graphically. Thanks -- =================================================================== Yu Wai CHEN Department of Biochemistry ................................. & Molecular Biology Faculty of Medicine tel: (604)-822 5007 2146 Health Sciences Mall fax: (604)-822 5227 University of British Columbia email: ywchen@laue.biochem.ubc.ca Vancouver BC V6T 1Z3 CANADA =================================================================== From owner-molec-model@net.bio.net Thu Apr 20 23:00:00 1995 Path: biosci!agate!howland.reston.ans.net!swrinde!gatech!newsfeed.pitt.edu!dsinc!ub!csn!magnus.acs.ohio-state.edu!infoserver.bgsu.edu!m32-109.bgsu.edu!user From: mikeh@bgnet.bgsu.edu (Michael A. Halbisen) Newsgroups: bionet.molec-model Subject: looking for grad school in Biotech Date: Fri, 21 Apr 1995 12:13:05 -0500 Organization: Bowling Green State University Lines: 14 Message-ID: NNTP-Posting-Host: m32-109.bgsu.edu Hi, I'm currently a junior chemistry major who is looking to apply to grad school this fall. However, I've been encountering some difficulty finding information on which schools have good Biotechnology programs. If anyone has some suggestions on a good grad school (for Ph.D) for Biotechnology, please let me know. I am mostly interested in projects that involve using molecular biology to genetically engeneer microbes to produce ( or do ) new things, such as making oil eating bacteria (as opposed to pharmacology). Any and all suggestions will be appreciated. Michael A. Halbisen mikeh@bgnet.bgsu.edu From owner-molec-model@net.bio.net Fri Apr 21 23:00:00 1995 Path: biosci!bloom-beacon.mit.edu!gatech!howland.reston.ans.net!vixen.cso.uiuc.edu!uwm.edu!reuter.cse.ogi.edu!netnews.nwnet.net!news.u.washington.edu!NewsWatcher!user From: coventry@chem.washington.edu (Mary Coventry) Newsgroups: bionet.molec-model Subject: Re: protein-protein docking program? Date: 22 Apr 1995 04:23:51 GMT Organization: UW Lines: 16 Distribution: world Message-ID: References: <3n8mdl$8j1@nntp.ucs.ubc.ca> NNTP-Posting-Host: nntp1.u.washington.edu In article <3n8mdl$8j1@nntp.ucs.ubc.ca>, ywchen@laue.biochem.ubc.ca (Y. W. Chen) wrote: > Dear all, > > I am studying the interaction of a protein enzyme with a protein substrate. > From mutation studies, I know roughly which region of the enzyme interacts > with which region of the substrate. Can someone recommend a program to > predict the docking of these 2 proteins? It would be best if the results > can be visualized graphically. Thanks > Well, it depends on does anybody solved (by X-ray or NMR) the 3-D structures of the wild-type or mutated enzymes of interest or not. If yes, there're some prospects but if not, you should satisfied yourself with primitive cartoons. :-< Cheers, Oleg Y. Fedoroff. From owner-molec-model@net.bio.net Mon Apr 24 23:00:00 1995 Path: biosci!SCRI.FSU.EDU!STRELETS From: STRELETS@SCRI.FSU.EDU ("VICTOR B. STRELETS") Newsgroups: bionet.molec-model Subject: Searching for proteins with structures on final stages of refinement Date: 25 Apr 1995 07:46:50 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 26 Sender: daemon@net.bio.net Distribution: world Message-ID: <950425104641.20409f46@scri.fsu.edu> NNTP-Posting-Host: net.bio.net Hi Netters, I'm finishing development of the new algorithm for the prediction of protein secondary structure. Method does not use information from multiple alignments and/or data structure probing experiments. It will be installed soon (in 1-2 weeks) as an e-mail server for open access, for a limited time until improved structure organization model will be finally refined to achieve maximal efficacy of this approach. Accuracy of the method appeared to be unexpectedly high and I would like to find possibilities to use references from experimentalists about structures which are in final stages of refinement to choose corresponding sequences as an prediction illustration in my publication. I don't need any info about structures itself and my interests are limited to aminoacid sequences (or references to PIR or SwissProt) only. Is there anybody who is ready to give such a reference(s)? And probably to discuss later results in comparison with real structure elements placement? I saw (twice) announcements about competition in the prediction of secondary structures for just refined (but still not bublished) structures. In principle this is same effort turned en mass. Could someone give me reference how to reach its organizers? Hope to hear from somebody, V. Strelets From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Newsgroups: bionet.molbio.proteins,bionet.molec-model Path: biosci!ns1.faseb.org!darwin.sura.net!nih-csl!rvenable From: rvenable@deimos.cber.nih.gov (Rick Venable) Subject: Re: Contacts for Molecules R Us? Message-ID: <1995Apr26.225503.23547@alw.nih.gov> Followup-To: bionet.molbio.proteins,bionet.molec-model Sender: postman@alw.nih.gov (AMDS Postmaster) Nntp-Posting-Host: deimos.cber.nih.gov Organization: FDA/CBER Biophysics Lab X-Newsreader: TIN [version 1.2 PL2] References: <95Apr25.214557edt.859@neuron.ai.toronto.edu> Date: Wed, 26 Apr 1995 22:55:03 GMT Lines: 32 Xref: biosci bionet.molbio.proteins:4397 bionet.molec-model:339 On 26 Apr 95 01:46:53 GMT Evan W. Steeg pontificated: > Although I greatly enjoy the NIH "Molecules R Us" web site, > I have some questions/comments for the people who run it, > and there is NO information given anywhere on the www pages > there as to whom I might contact. (That's quite odd -- almost > every site I have ever seen has many listings of the designers, > programmers, support personnel, etc.) The information is there, just not on every .html page. In particular, the "Molecules R Us" page is restricted to NIH only, and is a fill-in form for searching the Cambridge Crystal Data Bank (a commercial database). > If anybody knows whom I might contact about their service, > could you please let me know (NIH is a *big* organization :-) Indeed it is. The molecular modeling pages are maintained by Dr. Peter Fitzgerald, pcf@helix.nih.gov > (By the way, that web site is at > > http://www.nih.gov/htbin/pdb ) > > Evan I'd recommend starting at the top, e.g. http://www.nih.gov or perhaps http://www.nih.gov/molecular_modeling/mmhome.html -- Rick Venable =====\ |=| "Eschew Obfuscation" FDA/CBER Biophysics Lab |____/ |=| Bethesda, MD U.S.A. | \ / |=| / Not an official statement \ rvenable@deimos.cber.nih.gov \/ |=| \ or position of the FDA. / From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Path: biosci!WUCMD.WUSTL.EDU!stuart From: stuart@WUCMD.WUSTL.EDU (Stuart Green) Newsgroups: bionet.molec-model Subject: Tripos User Group Meeting May 24-26 1995 Date: 26 Apr 1995 14:49:55 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 14 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net The 1995 Tripos User Group Meeting takes place May 24-26 at the Ritz Carlton in St. Louis, U.S.A. Details of the meeting including agenda, abstracts, and registration information can be found at http://wucmd.wustl.edu/tug95/meeting.html --- Stuart M. Green stuart@wucmd.wustl.edu Center for Molecular Design Campus Box 1099 Washington University Tel 314-935-4671 St. Louis, MO 63130-4899 Fax 314-935-4979 From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!gatech!udel!ssnet.com!dmpcfc!David_H._Rominger From: David_H._Rominger@dmpcfc.com (David H. Rominger) Reply-To: David_H._Rominger@dmpcfc.com Newsgroups: bionet.molec-model Distribution: world Subject: Helical Wheels Date: 26 Apr 1995 09:49:14 GMT Message-ID: <206827486.117948458@dmpcfc.com> Organization: DMPC.PCS Lines: 14 Does anyone know of a program that will create helical wheels in color display? i know that a program GenWroks displays helical nets and that GCG also creates them, but not in color. Are there any other programs available. we are trying to examine the spanning domains of some GPCR's that are putatively Alpha-helices embeded in the membrane. Thanks Dave ------------------------------------------------------------------------- All comments/opinions in this message are solely those of the sender, and do not necessarily reflect the views of the employer. ------------------------------------------------------------------------- From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Path: biosci!rutgers!uwm.edu!vixen.cso.uiuc.edu!howland.reston.ans.net!swrinde!pipex!sunic!sunic.sunet.se!trane.uninett.no!news.uit.no!atf1!edvard From: edvard@atf1.uit.no (Oyvind Edvardsen) Newsgroups: bionet.molec-model Subject: Re: protein-protein docking program? Date: 26 Apr 1995 09:36:30 GMT Organization: University of Tromsoe, Norway Lines: 34 Distribution: bionet Message-ID: <3nl46u$pr5@news.uit.no> References: Reply-To: edvard@atf1.uit.no NNTP-Posting-Host: atf1.fagmed.uit.no >From bross@splatter.nas.nasa.gov (Bill Ross) >Subject: Re: protein-protein docking program? >Date: Wed, 26 Apr 1995 02:27:44 GMT > >> I am studying the interaction of a protein enzyme with a protein substrate. >> From mutation studies, I know roughly which region of the enzyme interacts >> with which region of the substrate. Can someone recommend a program to >> predict the docking of these 2 proteins? It would be best if the results >> can be visualized graphically. Thanks > >Look in J. Comp. Chem. for papers on Molecular Silverware by >folks at Rohm & Haas. > >Bill Ross Molecular Silverware is described by Blanco, M. in J.Comput.Chem. 12(2)237-47 (1991). -oed. -o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o-o- ___ _ | /| _| |_ _| __ _ _| _ _ |/_| \/ \/ | |\| |_| |_ |_| \/ |_|_ | |_| _\ |_' |\| / _____________________________________________________________________________ Dept. of Pharmacology, IMB | University of Tromsoe | TelePhone: +47 77 64 53 42 MH, Breivika | TeleFax: +47 77 64 53 10 N-9037 TROMSOE | Email: edvard@fagmed.uit.no NORWAY | URL: http://atf1.fagmed.uit.no/mgl.html ------------------------------------------------------------------------------ From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Newsgroups: bionet.molec-model Path: biosci!rutgers!uwm.edu!fnnews.fnal.gov!overload.lbl.gov!ames!cnn.nas.nasa.gov!splatter.nas.nasa.gov!bross From: bross@splatter.nas.nasa.gov (Bill Ross) Subject: Re: protein-protein docking program? Message-ID: Sender: news@cnn.nas.nasa.gov (News Administrator) Nntp-Posting-Host: splatter.nas.nasa.gov Organization: NAS/NASA Ames Research Center References: <3n8mdl$8j1@nntp.ucs.ubc.ca> Date: Wed, 26 Apr 1995 02:27:44 GMT Lines: 10 > I am studying the interaction of a protein enzyme with a protein substrate. > From mutation studies, I know roughly which region of the enzyme interacts > with which region of the substrate. Can someone recommend a program to > predict the docking of these 2 proteins? It would be best if the results > can be visualized graphically. Thanks Look in J. Comp. Chem. for papers on Molecular Silverware by folks at Rohm & Haas. Bill Ross From owner-molec-model@net.bio.net Tue Apr 25 23:00:00 1995 Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!news.cac.psu.edu!news.pop.psu.edu!hudson.lm.com!newsfeed.pitt.edu!uunet!utcsri!yonge.cs.toronto.edu!neuron.ai.toronto.edu!ai.toronto.edu!steeg Newsgroups: bionet.molbio.proteins,bionet.molec-model From: steeg@cs.toronto.edu ("Evan W. Steeg") Subject: Contacts for Molecules R Us? X-Nntp-Posting-Host: yonge.cs.toronto.edu Message-ID: <95Apr25.214557edt.859@neuron.ai.toronto.edu> Originator: root@yonge.cs.toronto.edu Organization: CS Lab, University of Toronto Date: 26 Apr 95 01:46:53 GMT Lines: 23 Xref: biosci bionet.molbio.proteins:4384 bionet.molec-model:334 Although I greatly enjoy the NIH "Molecules R Us" web site, I have some questions/comments for the people who run it, and there is NO information given anywhere on the www pages there as to whom I might contact. (That's quite odd -- almost every site I have ever seen has many listings of the designers, programmers, support personnel, etc.) If anybody knows whom I might contact about their service, could you please let me know (NIH is a *big* organization :-) (By the way, that web site is at http://www.nih.gov/htbin/pdb ) Thanks, Evan Evan W. Steeg (416) 978-5182 steeg@ai.toronto.edu Dept of Computer Science steeg@t13.lanl.gov University of Toronto, Toronto, Canada M5S 1A4 FAX: (416) 978-1455 From owner-molec-model@net.bio.net Thu Apr 27 23:00:00 1995 Path: biosci!SCRI.FSU.EDU!STRELETS From: STRELETS@SCRI.FSU.EDU ("VICTOR B. STRELETS") Newsgroups: bionet.molec-model Subject: Announcement: Protein Secondary Structure Prediction E-mail Server Date: 28 Apr 1995 13:07:38 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 57 Sender: daemon@net.bio.net Distribution: world Message-ID: <950428160727.2040ad67@scri.fsu.edu> NNTP-Posting-Host: net.bio.net Server Help File Prediction of Protein Secondary Structure ----------------------------------------- For a limited time, test version of the new algorithm for the prediction of protein secondary structure will be available through the E-mail server. Algorithm does not use multiple alignments or other homology/evolutionary related information and does not implement neural network techniques. It was designed primarily to handle predictions for the proteins which do not have any significant homology with proteins currently available in PDB. To access the server, send e-mail message containing amino acid sequence of your protein to the address bio@margit.scri.fsu.edu Message should contain: 1. Context -SSP- (Secondary Structure Prediction) in the Subject Line; 2. String -#START- immediately preceeding strings with amino acid sequence; 3. Strings with amino acid sequence; 4. String -#END- immediately following strings with amino acid sequence; 5. No non-aminoacid symbols (except of possible formatting blanks and digits) in the strings between #START and #END strings. Example of message body: ---------------------------- example start ------------------------------ #START PKPIFREYIGVKPNSTTLHD FPTEIINTET LEFHYILGFA IESYYESGKG TGTFEESWDV ELFGPEKVKN L K R R H P EVKV VISIGGRGVN TPF #END ----------------------------- example end ------------------------------- Server is VERY experimental, but I hope that all incoveniences might be compensated by the high prediction accuracy. Installed on the server model of the secondary structure organization will be updated in the process of ongoing model refinement. Prediction accuracy probably will increase, therefore update your results using latest model version. Due to the low restart frequency of the server, delays up to 20 minutes in the return of results should be expected. Note that algorithm have a limited accuracy in analysis of short (less than 60aa) and artificial sequences (like polypeptides with highly biased amino acid composition and/or with artificial pseudo-regularities). For helpful comments, send messages to strelets@scri.fsu.edu. Dr. Victor B.Strelets Supercomputer Computations Research Institute 400 Science Center Library FSU B-186, Tallahassee, FL 32306 Ph. (904) 644-6563 FAX (904) 644-0098 (Attn: Dr. Strelets) From owner-molec-model@net.bio.net Thu Apr 27 23:00:00 1995 Path: biosci!rutgers!gatech!howland.reston.ans.net!news.sprintlink.net!alsys1!stonefly.bioc.aecom.yu.edu!puius From: puius@telico.bioc.aecom.yu.edu (Yoram Puius) Newsgroups: bionet.molec-model Subject: 5'-CMP X-PLOR files Message-ID: <3627@alsys1.aecom.yu.edu> Date: 28 Apr 95 20:17:00 GMT Sender: news@alsys1.aecom.yu.edu Lines: 16 X-Nntp-Posting-Host: stonefly.bioc.aecom.yu.edu Dear netters: Does anyone have the parameter and topology files for cytidine 5'-monophosphate for X-PLOR? 2'-CMP and/or 3'-CMP would also be greatly appreciated. Thanks muchly in advance, Yoram _____________________________________________________________________________ Yoram A. Puius Albert Einstein College of Medicine puius@telico.bioc.aecom.yu.edu Department of Biochemistry M.D.-Ph.D. Class of 1999 [?] Bronx, NY 10461 _____________________________________________________________________________ "GOOD ta meetcha!" - Neelix _____________________________________________________________________________ From owner-molec-model@net.bio.net Thu Apr 27 23:00:00 1995 Path: biosci!adam.cc.sunysb.edu!news.sprintlink.net!howland.reston.ans.net!swrinde!pipex!uunet!juniper.almaden.ibm.com!almaden.ibm.com From: borges@almaden.ibm.com Message-ID: <19950427.091221.445@almaden.ibm.com> Date: Thu, 27 Apr 95 09:05:01 PDT Newsgroups: bionet.molec-model Subject: international conf./molecular modeling/functional dyes/Santa Cruz, Cal Lines: 48 3rd International Symposium on FUNCTIONAL DYES Sponsored by IUPAC & KCS when: July 16-21,1995; where: University of California at Santa Cruz, USA The symposium will be concerned with the following topics: DESIGN OF FUNCTIONAL DYE MATERIALS Novel materials, computer aided design, synthesis and structure, characterization and reactions, PROPERTIES, FUNCTIONS AND APPLICATIONS OF FUNCTIONAL DYES information recording, information display, energy conversion, non-linear optics, medical and biological aspects Plenary Lectures N Hampp(GER)-Functional Dyes from Nature: Potentials for technical applications M Irie(JPN)-Photochromic Diarylethenes for Photonic Devices GD Purvis(USA)-Computer Simulation of Dye absorption for Bench Chemists E Voegel(GER)-Porphyrinoid Macrocycles: A cornucopia of novel chromophores F Wudl(USA)-Photoinduced electron transfer from conjugated polymers to funcitonalized Buckminsterfullerene: Interactions between two unusual dyes *************************************************************************** COMPUTER AIDED DESIGN/invited lecturers: S. Nakamura/A new guiding principle towards the special design of organic functional molecules. J. Rice/Ab intio MO calculation of organic NLO molecules j McKelvey/A comparision of semi-empirical and ab intio dye structures and related Zerner-INDOS/S Hue predictions and more...... *************************************************************************** Invited Lectures JC CRANO(USA), J DAUB((GER), J WHITESELL(USA), F GARNIER(FRANCE), N KARL(GER), J KRUTAK(USA), C McARDLE(IRELAND), J McKELVEY(USA), S MIKI(JPN), JW MILEY(USA), T NAGAMURA(JPN), S NAKAMURA(JPN), H OGOSHI(JPN), K OKAMOTO(JPN), AP DE SILVA (USA), J RICE(USA), J SETO(JPN), H SUEMATSU(JPN), H VAN DEN BERGH(SWISS), Y WANG(USA), CONTRIBUTED PAPERS: will be included as oral and/or poster presentations. DEADLINES: Contributed paper: May 15, 1995(extended) Advanced Registration: May 15, 1995(extended) The 2nd circular is available from: Dr. K. Kanazawa, General Secretary of the Symposium IBM Research Division, Almaden Research Center 650 Harry Rd., K42/802, San Jose CA 95120-6099 USA or fax:(+81)408-927-2213, or e-mail kanazawa@almaden.ibm.com From owner-molec-model@net.bio.net Sun Apr 30 23:00:00 1995 Path: biosci!agate!howland.reston.ans.net!pipex!lyra.csx.cam.ac.uk!news From: Tim Hubbard Newsgroups: bionet.molbio.proteins,bionet.molec-model Subject: Are you interested in a structure prediction of your favourite protein? Date: 1 May 1995 14:20:56 GMT Organization: Centre for Protein Engineering Lines: 20 Message-ID: <3o2qo8$31j@lyra.csx.cam.ac.uk> NNTP-Posting-Host: macx1.mrc-lmb.cam.ac.uk Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 1.1N (Macintosh; I; 68K) X-URL: news:bionet.biology.computational Xref: biosci bionet.molbio.proteins:4426 bionet.molec-model:343 Are you working on a protein for which there is no X-ray or NMR structure at present (or likely soon) and would find even a rough 3-D structure useful? Would you be interested in pursuading a group of 4 people to work on your sequence night and day for a week this October? We are looking for suitable candidate proteins as targets for the IRBM practical course: 'frontiers of protein structure prediction'. If you are interested in your protein being considered as a target, please fill out the web form which can be found on the World Wide Web via: http://www.mrc-cpe.cam.ac.uk/predict/ on-line forms to apply to attend the workshop can also be found at this address (see accompanying email) Tim Hubbard, Anna Tramontano