From owner-repertoires@net.bio.net Mon Dec 01 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Stefan Unger Newsgroups: bionet.molecules.repertoires Subject: CYPRUS '98: New Technologies and Frontiers in Drug Research Date: 2 Dec 1997 09:28:08 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 146 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <660l5f$37b@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net CYPRUS '98: New Technologies and Frontiers in Drug Research May 4-8, 1998 Hawaii Beach Hotel Limassol, Cyprus Co-Sponsored by International Organization of Chemical Sciences in Development (IOCD) and ARRT International This remarkable conference addresses emerging technologies in drug discovery with special attention to their impact on the chemical and biochemical sciences. Sessions have been designed to present both background and futures and to provide optimal opportunity for discussion. In addition, special symposia on Applications of Structure-Based Design and Genomics in the Discovery of New Antimalarials and Challenges in Drug Design in Tropical Diseases have been included to bring forth the remarkable research advances in mechanism-based drug design in this area and the critical need for increased industrial participation in the resolution of a major worldwide health problem. The lecturers who have been invited to participate in Cyprus '98 have been selected on the basis of their prominence in the fields addressed. The program is designed for research managers and other pharmaceutical executives seeking a frontline view of emerging technologies and the associated opportunities in drug discovery. PROGRAM * Monday, May 4th Morning: The Changing Role of Chemistry in Drug Discovery (Chair: Harold Meyers, Sphinx/Lilly, USA) Beyond Rational Drug Design and Combinatorial Chemistry - What Lies Ahead? (Harold Meyers, Sphinx/Lilly, USA) Dynamic Combinatorial Chemistry: Evolutionary Formation and Screening of Molecular Libraries (Alexey Eliseev, SUNY Buffalo, USA) Integration of Structure-Based Design and Combinatorial Chemistry (Jin Li, Proteus Molecular Design, UK) Afternoon: Systematics in the Design and Production of Combinatorial Libraries (Petr Kocis, Zeneca Pharmaceuticals, DE, USA) New Methods of Small Molecule Detection in Mixture-Based Combinatorial Chemistry (Edward Wintner, Neogenesis, USA) Selected Short Oral Papers from Poster Presentations Evening: Conference Reception (Hawaii Beach Hotel) * Tuesday, May 5th Morning: Chemical Aspects of Membrane Components and Drug Transport (Chair: TBA) Topics: Macromolecular Interactions in Receptor-ligand Coupling; Signal Transduction; Role and Stereochemical Characteristics of Membrane Carbohydrates in Transport Mechanisms Afternoon: Artificial Membrane Applications in Lead Detection and Drug Development (Chair: Bruce Cornell, AMBRI/CRC Chatswood, Australia) Topics: Trans-membrane Measurements; Ion Channel Structure and Mimicry; Molecular Self-assembly Mechanisms Selected Short Oral Papers from Poster Presentations Evening: Civic Reception at Limassol City Hall * Wednesday, May 6th: Full Day Break Relax and enjoy Cypriot sun and hospitality, or join your colleagues in the full day Excursion into ancient Cyprus (optional, separate charge). * Thursday, May 7th Morning: Biomolecular Detection Mechanisms at Picomolar Concentrations (Chair: Alfred Kolb, Packard Instrument, USA) Nanoscale Detection of Biochemical Interactions (Alfred Kolb) High Density Imaging (J. Rushbrooke, Cambridge Imaging, UK) New Luminescence Technologies for Biochemical Assays (C.G.Morgan, Salford U, UK) Afternoon: Measurement of Single Molecule Binding (Chair: Hermann Gaub, Techn U Munich, Germany) The Chemical Physics of Single Molecule Action (Hermann Gaub) Biosensors Based on Molecular Recognition Force Measurements Between Individual Molecules (Richard J. Colton, Naval Research Laboratory, Washington, DC) Silicon Micromechanics and Fluidics in the Array Analysis of Biochemical Reactions (James Gimzewski, IBM Research, Switzerland) Selected Short Oral Papers from Poster Presentations Evening: Discussion Panel on Limits of Micronization in Chemical Synthesis and Biology (Coordinator: John Devlin, ARRT International, USA) * Friday, May 8th Morning: Applications of Structure-Based Design and Genomics in the Discovery of New Antimalarials (Chair: Thomas Wellems, Laboratory of Parasitic Diseases, NIAID/NIH, USA) Identification of a Key Protein in the Chloroquine Resistance Mechanism, Implications for Drug Development Strategies (T.E. Wellems, NIH) Plasmodium falciparum Dihydrofolate Reductase: From Molecular Cloning to Structural-based Design of Novel Antifolates (W. Sirawaraporn, Mahidol University, Thailand) Aspects of Antimalarial Drug Design (title tentative) (R. Ridley, Hoffmann LaRoche) Afternoon: Challenges in Drug Design in Tropical Diseases (Chair: Fred Opperdoes, Research Unit for Tropical Diseases, Catholic U Louvain, Belgium) Selected Short Oral Papers from Poster Presentations Evening: Conference Farewell Banquet (Hawaii Beach Hotel) REGISTRATION * Deadline for Posters: March 15, 1998 * Attendance Limited, Register Today! * Registration Fees: before February 1, 1998: US$695, academic $395 after February 1, 1998: US$795, academic $445 * Hotels range from $54 to $108 per person per day single occupancy CONTACT Contact ARRT International for full information: PO Box 1838 New Milford, CT 06776 Tel: 860-355-5195 Fax: 860-355-5975 email: arrtintl@prodigy.net note: please do NOT "REPLY" to this note, contact ARRT International at their emial address or phone. NEW CONTACT INFO!**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**& Stefan Unger, Ph.D. BioSoftware Marketing 2250 Webster, Ste B Palo Alto, CA 94301-4053 ph: 650-858-0522 fx: 650-494-6564 email: URL: http://bio.com/home/bsm/bsm.html BioSoftware Marketing specializes in a full range of marketing services (market studies to collateral design) for technical software and hardware companies. Product Manager, Scientific Software, Bio Online Store (http://store.bio.com/) **&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**&**& From owner-repertoires@net.bio.net Sun Dec 07 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Shu-Kun Lin Newsgroups: bionet.molecules.repertoires Subject: The 22nd monthly release of MDPI samples Date: 8 Dec 1997 02:10:11 -0800 Organization: University of Basel, Switzerland Lines: 37 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <66ggas$9pv@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net Dear Colleagues, We have just uploaded the 22nd monthly release of MDPI available samples for December 1997. There are 850 compounds. The database files can be downloaded from website http://www.mdpi.org/database.htm (or the mirror site in Europe http://www.unibas.ch/mdpi/database.htm). For obtaining the MDPI samples free of charge for academic research use or at low prices for companies, please visit http://www.mdpi.org/ or http://www.unibas.ch/mdpi/ websites for information. If you have any suggestions, please tell us so that we can improve MDPI samples exchange services. Happy holidays! Sincerely, Dr. Shu-Kun Lin Dr. Regis Turin -------------------------------------------------------- Molecular Diversity Preservation International (MDPI) A nonprofit organization for samples exchange services Saengergasse 25, CH-4054 Basel, Switzerland MDPI Website: http://www.mdpi.org/ e-mails: Info@mdpi.org Tel. +41 79 322 3379, Fax +41 61 302 8918 -------------------------------------------------------- From owner-repertoires@net.bio.net Tue Dec 09 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Claus Hultschig Newsgroups: bionet.molecules.repertoires Subject: Anti pVIII-Antibody - AP conjugate Date: 10 Dec 1997 09:43:09 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 15 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <66mipo$a5v@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net Dear all (in particular the Phage Displayers among you), Is anyone aware of an anti pVIII-AP conjugate? Unfortunately the HRP conjugate of Pharmacia might impose problems to my work and I would like to avoid the formation of Hydrogen Peroxide. A secondary antibody might not necessary be a real substitute either. Thank you very much for your time. Sincerely, Claus From owner-repertoires@net.bio.net Wed Dec 10 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Andrew Wallace Newsgroups: bionet.molecules.repertoires Subject: UK Lectureship in Molecular Cell Biology Date: 11 Dec 1997 05:18:48 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 48 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <66oohi$j6@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net LECTURESHIP IN MOLECULAR CELL BIOLOGY (as advertised in Nature, 11/12/1997, Classified 22) The Queen's University of Belfast School of Biology and Biochemistry Centre for Peptide and Protein Engineering Applications are invited from individuals with an excellent research record in molecular cell biology and, preferably, proven ability in teaching, for the above mentioned post. Applicants must have an honours degree (or equivalent) and a Ph.D. in Biochemistry, Molecular Biology, or a closely related subject. Research experience of applying molecular biology techniques to the study of the following areas of protein biochemistry: signal transduction pathways, protein processing and proteolysis, or mode of action of transcription factors, is essential. Expertise in differential display and yeast two-hybrid systems, would also be highly desirable. The successful candidate will be expected to develop an independent research programme and to foster collaborative links with other members of the Centre for Peptide and Protein Engineering, to which he/she will be associated. The successful candidate must also be committed to research-led teaching and will be expected to make an immediate (although relatively light) contribution to undergraduate teaching. Commencement date will be 1 October 1998 or an earlier agreed date. Informal enquiries may be directed to Dr. A. Wallace, School of Biology and Biochemistry, telephone +44 (0)1232 272089, FAX +44 (0)1232 236505, Email: a.wallace@qub.ac.uk. Salary Scale: 16,045 - 21,016 pounds Sterling per annum (Lecturer Grade A) placement depending on qualifications, research record and experience. Closing date: 30 January 1998 Committed to an Equal Opportunities policy and selection on merit, the University welcomes applications from all sections of the community. Under its affirmative action programme, the University particularly welcomes applications from women for academic posts. ------------------------------------------------------------------ Andrew Wallace, Ph.D, Queens University Belfast, N. Ireland (UK) a.wallace@qub.ac.uk http://web.qub.ac.uk/bb/awpage/wallace.html From owner-repertoires@net.bio.net Thu Dec 11 22:00:00 1997 Path: biosci!biosci!not-for-mail From: kshreder@znet.com Newsgroups: bionet.molecules.repertoires Subject: Updated WWWsite: The Antibody Resource Page Date: 12 Dec 1997 02:21:41 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 40 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <66r0bl$2k7@mserv1.dl.ac.uk> Reply-To: kshreder@znet.com NNTP-Posting-Host: net.bio.net Updated WWWsite: The Antibody Resource Page The Antibody Resource Page has been recently updated. The page will be invaluable to researchers and educators alike. Here is just some of what can be found on the page: 1. How to Find an Antibody - a variety of ways on and off the web to find the antibody you are looking for. 2. Online Companies - links to over 110 companies that sell antibodies or antibody related products. Is your company listed on this page? 3. Antibody Image Gallery - some animated gifs have recently been added 4. Bulletin Board - Have a question or have an answer? Then stop by and post a message. 5. Educational Resources - a variety of new links have been added. There are links to pages on immunochemistry, antibody production, autoimmunity, vaccines, immunology and much more. This page is divided up into sections on research, educational, and health resources. 6. The Latest in Antibody News - Get up-to-date, antibody-related articles on topics from academia and industry. ...and there is much more. Check it out at: http://www.antibodyresource.com/ Ps. Don't forget to visit our sponsors, Research Diagnostics, Inc. (http://www.researchd.com/absort1.htm) and Lab Vision Corporation (http://www.labvision.com/)! From owner-repertoires@net.bio.net Mon Dec 15 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Val Gillet Newsgroups: bionet.molecules.repertoires Subject: MGMS/CSA Conference announcement Date: 16 Dec 1997 09:50:13 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 34 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <676efq$nhr@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net CONFERENCE ANNOUNCEMENT Computational Approaches to the Design and Analysis of Combinatorial Libraries April 14-16th, 1998 Sheffield UK. A joint meeting by the Molecular Graphics and Modelling Society (MGMS) and the Chemical Structure Association (CSA) The conference will emphasise the design of diverse and focussed libraries; algorithms and methods for the selection of database subsets; the representation and searching of combinatorial libraries and analogous virtual databases; the design and use of both in-house and commercial software for diversity analysis; diversity indices; and the integration of diversity analysis with other computational tools, such as docking and QSAR. The meeting will be limited to 110 participants. Speakers include: John Blankley, Mark Bures, Alain Calvet, Keith Daves, Geoff Downs, Johann Gasteiger, Darren Green, Mark Hermsmeir, Robert Jilek, Victor Lobanov, Jonathon Mason, Chris Murray, Nick Pery, Stephen Pickett, Matthias Rarey, Marvin Waldman and Bohdan Waszkowycz. Further information including a Preliminary Programme and Registration Details can be found at: http://panizzi.shef.ac.uk/cisrg/mgms/index.html From owner-repertoires@net.bio.net Thu Dec 18 22:00:00 1997 Path: biosci!biosci!not-for-mail From: Andrew Wallace Newsgroups: bionet.molecules.repertoires Subject: Meetings Update 1998 Date: 19 Dec 1997 07:52:49 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 87 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <67e45p$d1o@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net Meetings and courses on combinatorial libraries and phage display. ***************************************************************** _________________________________________________________________ *** MEETINGS *** _________________________________________________________________ __________________________________________________________________ The 8th Cyprus Conference on New Methods in Drug Research Limassol, Cyprus May 4-9, 1998 Conference Executive: Chair: Alex Makriyannis (U. Conn. Storrs, USA) Committee: N. Castagnoli (USA), J.P. Devlin (USA), U.. Hacksell (Sweden), L.H. Hurley (USA) and M. Abou-Gharbia (USA) Conference Location Time and Registration: The Conference will take place from Monday, May 4th through Friday, May 9th 1998 at the five-star Hawaii Beach Hotel, Limassol, Cyprus. Attendance is restricted to 150 participants to encourage interaction. Registration fees ($595 per person; $395 for academics) includes attendance at all sessions and morning and afternoon breaks, but not meals. Sponsor: The European Federation of Medicinal Chemistry Contact: ARRT International, Inc., P.O. Box 1838, New Milford, CT 06776, USA Telephone: 860-355-5195; Facsimile: 860-355-5975; e-Mail: arrtintl@prodigy.net _________________________________________________________________ COMPUTATIONAL APPROACHES TO THE DESIGN AND ANALYSIS OF COMBINATORIAL LIBRARIES April 14-16th, 1998 Sheffield UK. A joint meeting by the Molecular Graphics and Modelling Society (MGMS) and the Chemical Structure Association (CSA) The conference will emphasise the design of diverse and focussed libraries; algorithms and methods for the selection of database subsets; the representation and searching of combinatorial libraries and analogous virtual databases; the design and use of both in-house and commercial software for diversity analysis; diversity indices; and the integration of diversity analysis with other computational tools, such as docking and QSAR. The meeting will be limited to 110 participants. Speakers include: John Blankley, Mark Bures, Alain Calvet, Keith Daves, Geoff Downs, Johann Gasteiger, Darren Green, Mark Hermsmeir, Robert Jilek, Victor Lobanov, Jonathon Mason, Chris Murray, Nick Pery, Stephen Pickett, Matthias Rarey, Marvin Waldman and Bohdan Waszkowycz. Further information including a Preliminary Programme and Registration Details can be found at: http://panizzi.shef.ac..uk/cisrg/mgms/index.html _________________________________________________________________ _________________________________________________________________ *** COURSES *** _________________________________________________________________ Phage Display of Combinatorial Antibody Libraries November 11 - 24 Organised by: C. Barbas, D. Siegel, G. Silverman Contact: Cold Spring Harbor Laboratory The Meetings & Courses Office PO Box 100, 1 Bungtown Road Cold Spring Harbor, NY 11724-2213 Phone: 516-367-8346 Fax: 516-367-8845 Email: meetings@cshl.org _________________________________________________________________ ------------------------------------------------------------------ Andrew Wallace, Ph.D, Queens University Belfast, N. Ireland (UK) a.wallace@qub.ac.uk http://web.qub.ac.uk/bb/awpage/wallace.html From owner-repertoires@net.bio.net Sun Dec 28 22:00:00 1997 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.molecules.repertoires Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 29 Dec 1997 03:00:49 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 236 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <199712281000.CAA20538@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-repertoires@net.bio.net Mon Dec 29 22:00:00 1997 Path: biosci!biosci!not-for-mail From: ic@clara.net (AT) Newsgroups: bionet.molecules.repertoires Subject: Amino Acid Transportation in bacteria Date: 30 Dec 1997 03:59:05 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 19 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <68anm9$ia3@net.bio.net> NNTP-Posting-Host: net.bio.net Hi, Does anyone have any idea about what (and which) web sites would be the best to look for different properties of chemicals listed, and how they effect the Amino Acid Transportation in bacteria:- carbonylcyanide m-chlorophenyl hydrazone (CCCP) Valinomycin Nigericin Thank you. John K. King Please reply to ic@clara.net