From owner-repertoires@net.bio.net Mon Jul 06 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Shu-Kun Lin Newsgroups: bionet.molecules.repertoires Subject: The 29th monthly release of MDPI samples Date: 7 Jul 1998 02:17:28 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 37 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net The 29th monthly release of MDPI samples Dear Colleagues, The 29th monthly release of MDPI available samples for July 1998 was just uploaded at http://www.mdpi.org/database.htm#new Most of these 546 samples are very interesting synthetic organic samples and natural products collected from a retired professor in the USA. Save the file as (or change the file name from exe file to) mdpi29.db and mdpi29.sdf file names respectively. (We still do not understand why the files, if directly uploaded without changing the names to xxx.exe, the downloaded files cannot be open properly.) Sincerely, Shu-Kun Lin --------------------------------------------------------- Dr. Shu-Kun Lin Molecular Diversity Preservation International (MDPI) Saengergasse 25, CH-4054 Basel, Switzerland http://www.mdpi.org/ MOLECULES http://www.mdpi.org/molecules/ ECSOC-2 http://www.mdpi.org/ecsoc-2.htm E-mail lin@mdpi.org Tel. +41 79 322 3379, Fax +41 61 302 8918 -------------------------------------------------------- From owner-repertoires@net.bio.net Tue Jul 07 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Michael Sherrell Newsgroups: bionet.molecules.repertoires Subject: Sequencers and synthesizers Date: 8 Jul 1998 05:07:02 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 47 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <01BDA9B7.B5F6C680@sf-pm17-36-100.dialup.slip.net> NNTP-Posting-Host: net.bio.net I have a number of peptide and oligo synthesizers and sequencers for = sale: PerSeptive 9050, ~$10K PerSeptive Expedite 8909, <=3D $14K ABI 394, rebuilt, warranteed, Oligonet-ready, ~$12K ABI 394, rebuilt, warranteed, non-Oligonet, ~$11K ABI 391, rebuilt, warranteed, $7K ABI 430, rebuilt, warranteed, ~$12K ABI 433, rebuilt by ABI, warranteed, < $40K ABI 373 stretch, 5-filter, Genescan, 36-lane, $29K ABI 477, <=3D $10K ABI 120, 130, $2.5K also: LC-MS: Finnigan MAT 900, <$50K Finnigan MAT 90, ~$45K MicroMass Quattro II, ~$200K =09 MALDI-TOF: HP, masses to 500 KDa, lightly used, <=3D$60K Finnigan Laser MAT 2000, <$40K Other expensive hi-tech items: Bio-Dot sub-microliter 8-channel aspirate/dispense system (typically = 96-well microplate source, glass slide, microwell plate or membrane = target), < 1 year old Molecular Devices 445SI-MAC Phosphorimagers, ~ 3 years old, currently = operating and under maintenance contact, pretty low price I also have available a few other synthesizers and sequencers and a = wide selection of HPLCs, mass specs, and other lab instruments. Please contact me to discuss any of these items, or if you have any = items you might like to sell. Michael Sherrell Grizzly Analytical (USA) 707 887 2919/fax 707 887 9834 www.grizzlyanalytical.com From owner-repertoires@net.bio.net Sun Jul 19 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Ron Grigg Newsgroups: bionet.molecules.repertoires Subject: CASE studentship available, Leeds, UK Date: 20 Jul 1998 02:09:04 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 21 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Dear All, There is a CASE studentship available at the Department of Chemistry, University of Leeds under the supervision of Prof. Ron Grigg. The ideal start date is 1st October 1998. If anyone is interested, or knows of any current graduate students who are interested, in research in the molecular diversity/combinatorial chemistry field then they should contact Ron Grigg for further details. Tel/Fax 0113-233-6501 mailto:r.grigg@chem.leeds.ac.uk Thanks, Gareth Jenkins. From owner-repertoires@net.bio.net Sun Jul 19 23:00:00 1998 Path: biosci!biosci!not-for-mail From: James Larkin Newsgroups: bionet.molecules.repertoires Subject: Upcoming Meetings Date: 20 Jul 1998 01:52:52 -0700 Organization: Cambridge Healthtech Institute Lines: 22 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <35AA10C8.2D3E@cambridge.org> NNTP-Posting-Host: net.bio.net I thought theses 3 conferences might be of interest to your group Strategies and Techniques for Identification of NOVEL BIOACTIVE COMPOUNDS October 8-9, 1998 Zurich, Switzerland NMR TECHNOLOGY: Developments and Applications October 29-30, 1998 Baltimore, Maryland Advances in MASS SPECTROMETRY for Genomic and Biomolecular Research January 7-8, 1999 Orlando, Florida For more information please contact Cambridge Healthtech Institute 1037 Chestnut St.=20 Newton Upper Falls, MA 02464 PH: 617-630-1300 Fax: 617-630-1325 Email chi@healthtech.com From owner-repertoires@net.bio.net Wed Jul 22 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Shu-Kun Lin Newsgroups: bionet.molecules.repertoires Subject: ECSOC-2 calling for papers Date: 23 Jul 1998 05:07:52 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 27 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Dear Colleagues, The deadline for submission of papers to the Second International Electronic Conference in Organic Synthesis (ECSOC-2) is August 1st, 1998. This Conference will take place during September 1-30 on the Internet, providing the opportunity for immediate feedback and informal discussions. The organisers would like to encourage you to use this medium to have your research results made available to the global chemistry community. Please visit the Conference Website for further information. ECSOC-2 Website: http://www.mdpi.org/ecsoc-2.htm Dr. Esteban Pombo-Villar ECSOC-2 Chairman Novartis Pharma CH-4002 Basel, Switzerland phone +41 61 324 9865, fax +41 61 324 9794 e-mail ESTEBAN.POMBO@pharma.novartis.com From owner-repertoires@net.bio.net Wed Jul 22 23:00:00 1998 Path: biosci!biosci!not-for-mail From: "Rich Lysakowski, Ph.D." Newsgroups: bionet.molecules.repertoires Subject: Deadline rapidly approaching for Electronic Lab Notebooks Course Date: 23 Jul 1998 01:36:30 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 107 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Dear Colleague, The deadline is quickly approaching for course preregistration for the American Chemical Society (ACS) short course covering electronic notebooks, groupware, document management, and related systems. This details of exciting course are given below. It is being held in Boston, one of the world's most exciting cities! Please register directly with the ACS at http://www.acs.org/education/profdevl/sccm01.html. To receive the preregistration discount, please register within the next two weeks. Thank you. =========================================================================== === "Electronic Lab Notebooks and R&D Team Computing Systems" Who Should Attend Scientists, managers, engineers, MIS and computer support personnel, regulatory staff in the chemical, pharmaceutical, environmental, biotech, food and beverage, and related areas. This course will be of interest to anyone needing to know the legal, regulatory, technical, and social aspects of electronic notebooks, recordkeeping, document management, or other collaborative systems used in R&D or testing labs. How You'll Benefit from This Course Stay current with latest technologies, regulations, and legal imperatives for laboratory recordkeeping. Quickly assess your company's infrastructure and cultural readiness to use electronic lab notebooks; learn how to prepare them to use electronic lab notebooks. Learn when to buy versus build electronic notebook systems; how to grow them into full-blown R&D Team Computing Systems. Get practical tips for evaluating and selecting vendors and systems. See key products evaluated and demonstrated without vendor hype. Course Topics Introduction to Collaborative Electronic Lab Notebooks and R&D Team Computing Systems: legal and patent aspects; regulatory requirements and procedures; technical design concepts; social and cultural aspects. Electronic Recordkeeping and Records Management Systems good recordkeeping practices; the 13 fundamental properties of electronic records; electronic records, signatures, notary and security systems for protecting intellectual property; acceptable optical and magnetic storage media for electronic records. Practical Aspects of Applying The Technologies: understanding the costs and benefits of electronic notebooks and team computing systems in your lab; implementing systems to meet legal, regulatory, technical, and social needs; technical requirements: basic and advanced design & usability issues; connecting existing instruments, LIMS, other automation systems; end-user experiences and case studies; addressing social and cultural issues; methodologies to ensure successful pilot projects and system rollouts for small to large organizations; augmenting team intelligence with team computing systems. The Instructors Richard Lysakowski, Ph.D. is Executive Director, Collaborative Electronic Notebook Systems Association (CENSA), Woburn, Massachusetts. James T. Currie Jr., Ph.D. is an instructor, researcher, and engineer for CENSA. Apologies in advance for any duplications in the mailing lists. From owner-repertoires@net.bio.net Sun Jul 26 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Shu-Kun Lin Newsgroups: bionet.molecules.repertoires Subject: "Chemical samples preservation" to be discussed at ECSOC-2 Date: 27 Jul 1998 01:39:47 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 54 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Hi, colleagues, The disposal of old chemical samples is costly and generates environmental problem, while old samples can be used for many other screening purposes. However, there are many technical problems regarding samples management. As one of the two Section Conveners of Section E of The 2nd International Electronic Conference on Synthetic Organic Chemistry (ECSOC-2, at http://mdpi.org/ecsoc-2.htm), I would like to invite chemists contribute short papers expressing ideas on the samples preservation project. The format might be that of the short comments published in many journals. MDPI published MOLECULES (http://mdpi.org/molecules/) is the first journal encouraging chemists to deposit and exchange samples. In order to promote this activity, I thought about purchasing ca. 0.5 g ( or any amount 5mg-500g) of samples of the rare compounds described in any MOLECULES papers. The nonprofit organization MDPI has put great efforts on collecting all old samples from retired professors and in many cases pay cash to purchase all of them. MDPI further rewards sample contributor afterwards if any part of the samples are sold in the worldwide samples exchange project (For more information, please visit http://mdpi.org/ website). It has been my dream that no old samples are trashed but all are preserved by MDPI. I would like to open active discussions at Section E, where the topic includes "Information and Compound Archives Management and Internet Application: Molecular diversity studies, literature, databases, chemical sample libraries, and 2D and 3D structural presentation". If you have any comment, please let me know. I will appreciate it if you support us. Shu-Kun Lin President of MDPI Editor, MOLECULES (vol.3 1998) --------------------------------------------------------- Dr. Shu-Kun Lin Molecular Diversity Preservation International (MDPI) Saengergasse 25, CH-4054 Basel, Switzerland http://www.mdpi.org/ MOLECULES http://www.mdpi.org/molecules/ ECSOC-2 http://www.mdpi.org/ecsoc-2.htm E-mail lin@mdpi.org Tel. +41 79 322 3379, Fax +41 61 302 8918 -------------------------------------------------------- From owner-repertoires@net.bio.net Mon Jul 27 23:00:00 1998 Path: biosci!biosci!not-for-mail From: KRISTEN LANGEVIN Newsgroups: bionet.molecules.repertoires Subject: The World's Drug Discovery Meeting Place Date: 28 Jul 1998 03:30:58 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 38 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net IBC's 3rd International Exposition and Symposium Drug Discovery Technology '98 Breaking the Bottleneck: Innovation and Speed in Drug Discovery August 10-13, 1998, Sheraton Boston Hotel & Hynes Convention Center, Boston, MA Have you registered? Your competitors have! Only 3 weeks left! Don't miss your chance to join industry experts from around the world for 3 days of in-depth discussions and presentations. This event sold out in 1996 and 1997 and is expected to sell out again this year. Special Highlights: *Keynote Address: William A. Haseltine, Chairman & CEO, Human Genome Sciences, Inc. *International assembly of over 50 speakers from top companies *$1000 Poster Award *Over 100 confirmed Exhibitors *Choice of two comprehensive tracks: Genomics and Drug Discovery and/or Chemistry, Screening, and Drug Discovery *A choice of 6 sponsored technology workshops *Numerous Networking events Visit our web site at http://www.ibcusa.com/conf/drugdisc for detailed agendas and registration information or contact Kristen Langevin at 508-804-5257 or klangevin@ibcusa.com. From owner-repertoires@net.bio.net Tue Jul 28 23:00:00 1998 Path: biosci!biosci!not-for-mail From: "ls10@zsu.edu.cn" Newsgroups: bionet.molecules.repertoires Subject: how to draw a recombinat plasmid? Date: 29 Jul 1998 03:21:23 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 8 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <35BFB7DF.2D98@zsu.edu.cn> Reply-To: ls10@zsu.edu.cn NNTP-Posting-Host: net.bio.net hi, i want to make a whole procedure of the construction of some recombinant plasmids which involve drawing some graphs of plasmid. but i don't know any software available for it. anyone has any idea of it? From owner-repertoires@net.bio.net Wed Jul 29 23:00:00 1998 Path: biosci!biosci!not-for-mail From: Tara Dyson Newsgroups: bionet.molecules.repertoires Subject: CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT Date: 30 Jul 1998 07:11:16 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 61 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <6ppqnm$q7o@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net > ANNOUNCING - CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT - A > NEW JOURNAL FOR DRUG R&D CHEMISTS > > FREE SAMPLE COPIES AVAILABLE > > Current Opinion in Drug Discovery and Development is a new bimonthly > review journal published by Current Drugs Ltd, which covers all of the > chemical aspects involved in the drug discovery and development > process. > > Edited by James A Bristol, Simon F Campbell and Paul J Reider, the > journal is designed to combat the proliferation of the scientific > literature by giving the reader an intelligent overview of the > important developments across the entire subject. Its contents are > divided into six major sections, each of which is reviewed in turn > throughout the year. > > Chemistry of Drug Design and Lead Optimization > Chemistry of Biological Processes > Chemistry of Process Development > Chemistry of Metabolic and Toxicological Processes > Chemistry of Biological Products > Management of Biological and Chemical Information > > Contributions from internationally recognized researchers are all > invited and peer-reviewed by an Editorial Board of distinguished > members of the scientific community. The views of experts in the form > of editorial overviews, review articles, annotated paper and patent > coverage and a web watch section are contained in each section. > > For further information, see the Current Drugs website > http://www.current-drugs.com > > To order your FREE SAMPLE COPY, please send an email to > codddsamp@cursci.co.uk > and supply us with your name, company, address, telephone number and > email details. > Kind regards > Tara Dyson > Editorial Director > Current Drugs Ltd > Middlesex House > 34-42 Cleveland Street > London > W1P 6LB > UK > Tel: +44-171-580-8393 > Fax: +44-171-580-5646 > Email: tara@cursci.co.uk > http://www.current-drugs.com > From owner-repertoires@net.bio.net Thu Jul 30 23:00:00 1998 Path: biosci!biosci!not-for-mail From: janet stewart Newsgroups: bionet.molecules.repertoires Subject: Science editing and writing Date: 31 Jul 1998 02:36:39 -0700 Organization: Bell Solutions Lines: 14 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <35C0D374.4071@sympatico.ca> Reply-To: janet.stewart@sympatico.ca NNTP-Posting-Host: net.bio.net [This is not strictly within the charter of molreps, but I thought it might be of interest so I will allow it this time - The Moderator] Scientific articles edited within 2 business days. Experienced editor and writer will render your texts in clear, concise and impeccable English via exchange of attached files over the Internet. For more information about my resume, rates, etc., please consult my Web site at: http://www3.sympatico.ca/janet.stewart/