From owner-repertoires@net.bio.net Sun Sep 06 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: Rania Horaitis <horaitis@ariel.ucs.unimelb.edu.au>
Newsgroups: bionet.molecules.repertoires
Subject: Registration reminder
Date: 7 Sep 1998 09:42:07 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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Here is a reminder to those who have not yet registered. This is a group
email so  you may have registered. Some confirmed speakers are listed below.

Hugo Mutation Database Initiative
5th International Meeting
Denver, Colorado, USA, 1998

This meeting will be held the day before the Denver meeting of the American
Society of Human Genetics- 

TIME:			8.00am-7.00pm
DATE:			27th October 1998
VENUE:		Denver Marriot City Centre, Denver Ballroom I/II/III
REGISTRATION:	Academic & Non-Commercial registrants-US$85
			Commercial registrants:-US$150
			Lunch is included.
ORGANISERS:	R. Horaitis, R.G.H. Cotton (Australia)
REGISTRATION:	Fill in attached form and return. If you cannot open
attachment, form 			is available on our website.
			Contact R. Horaitis
				Email:	  horaitis@ariel.ucs.unimelb.edu.au
				Fax:   61-3-9288-2988
WEBSITE:		http://ariel.ucs.unimelb.edu.au:80/~cotton/mut_database.htm

In association with the annual meeting of the ASHG (American Society of
Human Genetics), the HUGO Mutation Database Initiative is hosting its 5th
International Meeting in Denver on the 27th October, 1998. The initiative
aims to co-ordinate the collection and distribution of accurate information
via the www. In earlier meetings the emphasis was on identifying the issues
and hearing of new projects and proposals. Lately, with the two meetings
per year and with the ease of electronic publication a one day meeting
appears appropriate with talks mainly being working group reports. Some
talks however will be invited. It is expected that registrants will take
the opportunity to present new databases or ideas as posters. Talks may be
invited from these. Anyone interested in this worldwide Initiative is
invited to attend. We are charging a registration fee to offset costs and
lunch will be included. If you are interested in participating, please fill
in the attached registration form below as soon as possible for
organisational reasons.

Poster entries are to submit abstracts as soon as possible.

Sponsorship is invited from those companies interested in mutation databases.

Reports from Working Groups-

*confirmed speaker

    Nomenclature				Stylianos Antonarakis
*  Content & Software			Charles Scriver
*  HGMD					Michael Krawczak
*  EBI						Heikki Lehvaslaiho
*  NCBI					Steve Sherry
    OMIM					Victor McKusick
*  Alliance					Dick Cotton
*  Copyright & Intellectual Property	Doug Wallace or Michael Brown
*  SNP/Polymorphism			Pui-Yan Kwok or Michael Brown
    National & Ethnic databases		?
*  Patient aspects of databases		Sue Mize or Chester Whitley
*  Quality control and peer review	Dick Cotton
*  Spectral databases.			Tina Hernandez


Scientific Presentations-Oral:

*  P.S.Harper		"The Frequency of Inherited disease database"
*  C. Beroud			"Universal Mutation Database"
*  R. Hardison		"Human Haemoglobin variants"


Scientific Presentations-Oral and Poster.

To be confirmed

Proposals & Plans-Ratification Meeting.


***

TO REGISTER:	Fill in registration form available on our
website- http://ariel.ucs.unimelb.edu.au:80/~cotton/register.htm and 
return





From owner-repertoires@net.bio.net Tue Sep 08 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: "Dr. Wendy A. Warr" <wendy@WARR.COM>
Newsgroups: bionet.molecules.repertoires
Subject: Combinatorial catalysis etc.
Date: 9 Sep 1998 03:15:06 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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The following message, sent to me by John Hewes of NIST, might be of
interest to members of this list. He has given me permission to post it.
Please contact him directly if you want to follow up on this.
Wendy
_____________________________________________________________________

I am encouraging industry to start thinking about
submitting NIST/Advanced Technology Program
competition proposals in the area of combinatorial
methodologies applied to catalysis (widely
interpreted). The NIST/ATP combinatorial web page
url is
http://www.atp.nist.gov/www/ccmr/ccmr_off.htm.

I will be hosting a one-day workshop on
combinatorial chemistry at the ATP "annual
convention" in Atlanta November 18. This will
feature industry leaders discussing combinatorial
chemistry applied to catalysis and its high-risk
technology needs. You might like to browse
http://www.atp.nist.gov/fallmeeting for more info.

ATP does not announce Focused Programs until after
funding is approved by Congress in
October-November.  Again,  Proposers should NOT
wait until competition announcements to put a
proposal/team together!

Please do not hesitate to contact me for
additional information.

Best regards,

John Hewes
tel :(301) 975-5416


--
Dr Wendy A Warr
Wendy Warr & Associates, 6 Berwick Court
Holmes Chapel, Cheshire CW4 7HZ, England
Tel/fax +44 (0)1477 533837
wendy@warr.com   http://www.warr.com




From owner-repertoires@net.bio.net Tue Sep 08 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: "Lindberg, Iris" <ilindb@LSUMC.EDU>
Newsgroups: bionet.molecules.repertoires
Subject: postdoctoral position for enzymologist
Date: 9 Sep 1998 02:58:49 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 29
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Postdoctoral position available any time in 1999 to study the enzymology
and cell biology of
peptide hormone/neurotransmitter synthesizing enzymes (the eukaryotic
subtilisins known as prohormone convertases; see for example Muller et al,
J. Cell. Biol. 139, 625-638, 1997; or Zhu et al, J. Biol. Chem. 273,
1158-1164, 1998). Current projects involve transgenic technology (7B2 ko),
and/or PC  PC inhibitor structure-function analyses. Prefer motivated
recent Ph.D. with experience in enzymology and/or neuroendocrinology for
this position in med school laboratory in New Orleans, an exciting, low
cost-of-living city. Competitive salary w/yearly travel to relevant
meetings. If interested, please send your CV and names and phone numbers of
three references to:

Iris Lindberg, Ph.D.
Dept. of Biochem & Mol Biol/Neuroscience Center, LSU Med Ctr
1901 Perdido St New Orleans, LA 70112
email: ilindb@lsumc.edu
http://www.lsumc.edu/campus/bioc/Lindberg/Lindberg.htm

Iris Lindberg,
Professor, Biochem & Mol Biol
LSUMC
1901 Perdido St
New Orleans LA 70112
phone 504-568-4799
fax 504-568-3370




From owner-repertoires@net.bio.net Tue Sep 08 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: lefranc@ligm.igh.cnrs.fr
Newsgroups: bionet.molecules.repertoires
Subject: IMGT News - August 1998
Date: 9 Sep 1998 09:18:24 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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Dear Colleague,

Please find below the IMGT NEWS - August 98 announcement.
Best Regards

Marie-Paule Lefranc
----------
IMGT NEWS - August 1998 - IMGT, http://imgt.cnusc.fr:8104

"IMGT Scientific Chart - IMGT Repertoire - New Interface"

IMGT, the international ImMunoGeneTics database, announces:

- IMGT Scientific Chart: A description of IMGT standardized rules to ensure
the highest quality data (unique numbering, gene name nomenclature, FR-IMGT
and CDR-IMGT regions,...)
- IMGT Repertoire: IMGT expertised immunoglobulin and T cell receptor gene
tables ("colliers de perles" representations, alignments and tables of
alleles, protein displays,...)
- a New IMGT/LIGM-DB interface and eight choices to see results (IMGT
annotations, IMGT flat files, coding regions with protein translation,
external references,...)

Also new:

- the Mouse (Mus musculus) germline IGKV gene table
- IMGT reference sequences in FASTA format, accessible from IMGT Repertoire
and from IMGT/DNAPLOT search page, for downloading

IMGT is freely accessible at http://imgt.cnusc.fr:8104

Flash on IMGT:
> 27 000 Ig and TcR sequences of 81 species
> 26 000 sites connected since 1st of january 96
> 4 000 requests a week

IMGT Initiator and coordinator:
Prof. Marie-Paule Lefranc
Laboratoire d'ImmunoGenetique Moleculaire, LIGM
UPR CNRS 1142, IGH, 141 rue de la Cardonille
34396 Montpellier Cedex 5 - France
T=E9l. : +33 (0)4 99 61 99 65 - Fax : +33 (0)4 99 61 99 01
lefranc@ligm.igh.cnrs.fr

IMGT references :
Lefranc M.-P., Immunology Today, 18, 509 (1997)
Lefranc M.-P., Exp. Clin. Immunogenet., 15, 1-7 (1998)
Pallares N. et al., Exp. Clin. Immunogenet., 15, 8-18 (1998)
Lefranc M.-P. et al., Nucleic Acids Research, 26, 297-303 (1998)
-------------

_____________________________________________
Laboratoire d'ImmunoGenetique Moleculaire, LIGM
UPR CNRS 1142, IGH
141 rue de la Cardonille
34396 Montpellier Cedex 5 - France
Tel: +33 (0)4 99 61 99 65 - Fax: +33 (0)4 99 61 99 01
IMGT, the international ImMunoGeneTics database
http://imgt.cnusc.fr:8104




From owner-repertoires@net.bio.net Mon Sep 14 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: John Porco <JPorco@ARGOTECH..COM>
Newsgroups: bionet.molecules.repertoires
Subject: Scientist/Postdoctoral Positions
Date: 15 Sep 1998 07:52:35 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 37
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Argonaut Technologies is a leading developer of new technologies for
automated synthesis and drug discovery, and currently has two 
positions open in our parallel medicinal chemistry group:

 SCIENTIST (98-022) and POSTDOCTORAL SCIENTIST (98-018)

Responsibilities include research on polymer reagents/ scavengers and
utilization of novel instrumentation for parallel synthesis and 
combinatorial chemistry. You will be demonstrating parallel 
synthesis, purification, and characterization of organic compounds 
using both solution and solid phase methods. In addition, you will 
also develop new methodologies for parallel medicinal chemistry and 
reaction execution. A Ph.D. in organic chemistry is required. 
Duration for the postdoctoral appointment is two years.

Interested parties should send their resumes to:

                                    Argonaut Technologies
                                    Attn: Human Resources
                                    Job Number (#)
                                    887 Industrial Road, Suite G
                                    San Carlos, CA 94070
                                    FAX: 650-598-1359

John A. Porco, Jr.
Director, Parallel Medicinal Chemistry
Argonaut Technologies
887 Industrial Road, Suite G
San Carlos, CA  94070
phone: 650-598-1350 x 213
fax: 650-598-1359







From owner-repertoires@net.bio.net Mon Sep 14 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: Binghe Wang <Binghe_Wang@NCSU.EDU>
Newsgroups: bionet.molecules.repertoires
Subject: postdoctoral positions
Date: 15 Sep 1998 07:50:19 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 39
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POST-DOCTORAL POSITIONS:There are three  post-doctoral positions 
available immediately in the general area of medicinal/bioorganic 
chemistry.  The first one will be focused on the synthesis and 
biological evaluation of targeted drug delivery systems.  The second 
position is on the development of new linkers for solid phase 
peptide/organic synthesis.  The third position is on either the 
development of new MRI contrast agents or new fluorescent sensors.  
All positions require strong synthetic skills.  A Ph.D. in organic, 
or medicinal, or bioorganic chemistry is required.  If interested, 
please send a CV and arrange to have three reference letters sent to:

Dr. Binghe Wang
Department of Chemistry
North Carolina State University
Raleigh, NC 27695-8204
(919) 515-2948 (phone)
(919) 515-3757 (fax)
binghe_wang@ncsu.edu
http://www2.ncsu.edu/ncsu/chemistry/bw.html


******************************************************************************
Binghe Wang
Department of Chemistry
430 Dabney Hall
North Carolina State University
Raleigh, NC 27695-8204

Phone (919) 515-2948
fax (919) 515-3757
e-mail: binghe_wang@ncsu.edu
Learn more about the Wang group at http://www2.ncsu.edu/ncsu/chemistry/bw.html
******************************************************************************







From owner-repertoires@net.bio.net Mon Sep 21 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: "Rich Lysakowski, Ph.D." <rich@CENSA.ORG>
Newsgroups: bionet.molecules.repertoires
Subject: Career Opening at CENSA - Senior Member Recruitment Specialist
Date: 22 Sep 1998 07:48:07 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 170
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CENSA, the Collaborative Electronic Notebook Systems Association is
searching for Senior Member Recruitment Specialists to help continue
our excellent growth.  Our group has developed a successful record
of growth over the last 2 =BD years and we are looking for senior
people to help us manage and accelerate the growth.  Please
consider the attached job description and let us know if you want
to help us to continue our success.  Following is a description of
our group, goals, and members.

CENSA is the first market development association.  CENSA focuses
on creating and accelerating markets for "new information automation"
for science and technical applications.  By "new automation" we mean
electronic notebooks and related recordkeeping systems, integrated
document management and workflow systems, groupware and information
sharing, collaborative computing, and knowledge management systems.

CENSA works in pharmaceutical, biotechnology, chemical, healthcare,
food, beverage, consumer products, high technology, and other
industries where government regulations or patents are fundamental
to product research, development, and manufacturing.

CENSA is comprised of the following Fortune 200 and other
organizations:

Abbott Laboratories
Adobe Systems
Boehringer Ingelheim
Bristol-Myers Squibb
Computer Sciences Corporation
Documentum
Dow Chemical Company
Dow AgroSciences
Doxis
GlaxoWellcome
Monsanto Life Sciences
Pfizer
Procter and Gamble
PSSoftware
Purdue Pharmaceuticals
Rohm and Haas Company
ScriptSafe
United States Department of Energy
UOP, LLC (an Allied Signal Company)

We will announce several new members as soon as we get clearance from
them to do so.

We look forward to hearing from you.

Sincerely,


Dr. Rich Lysakowski
Executive Director



Member Recruitment Specialist  (Technical Salesperson)

Our exciting leading-edge collaborative programs improve a
ns in pharmaceutical, chemical,
biotechnology, healthcare, and high technology companies.  As our
recruitment specialist, you will lead and manage member recruitment
and product sales for the company.  Your business skills, market insight
and knowledge will help drive our work in market development for
electronic notebook and recordkeeping systems, collaborative computing
systems, scientific software, groupware, document management, Intranets,
client/server systems, and application integration tools.

Your overall responsibilities will include:

=B7    Lead the company's recruitment and product sales efforts
=B7    Design and implement programs to attract new members
=B7    Manage the sales effort within budget and expense goals

You will be responsible for qualifying prospective members, forming
relationships and educating them, negotiating contracts and finalizing
new memberships.  You will be expected to review, approve (and if
necessary, improve) all collateral and materials that you will use
with prospective members.  Prior experience doing consultative sales,
solution selling and/or concept selling will serve you well in this
job.   Process support systems will be provided to assist you.

KNOWLEDGE OF TECHNOLOGIES AND PRODUCTS:

Familiarity and working knowledge of one or more of the following
relevant technologies and products will be helpful to you in this
job.  The ability to quickly pick up technologies unfamiliar to you
is important.

=B7    Groupware, document and workflow management, and collaborative
computing tools,
=B7    World Wide Web and Internet protocols,
=B7    Electronic recordkeeping and records management systems and
applications,
=B7    Middleware and systems integration tools,
=B7    Lab automation and robotics, LIMS, instrument interfacing;
=B7    Chemical, biological and materials informatics systems from
various vendors (e.g., CAS, MDL, Beilstein, Daylight, Synopsis,
Oxford Molecular Group, MAG, others)
=B7    Combinatorial chemistry, synthesis, and high throughput
screening technologies.

AVAILABILITY=20

Start immediately.  Strong preference given to people already living
in the Northeast United States.  Must relocate to Boston area.

SALARY RANGE:  Expected compensation can go over $150K including
bonuses if you achieve revenue goals.  Actual compensation will depend
on the prior experience, qualifications, skills and motivation you
bring to the job,.  Stock options or other ownership options may be
given to the right person with the appropriate level of commitment.


WORK DIRECTION:  You will work with and under the direction of the
Association Executive Director, who indicates general assignments, and
priorities.   You will be expected to independently perform recurring
assignments such as conducting recruitment events, and communicating
with current and prospective members and customers.  Some administrative
support will be available.

EDUCATION AND TRAINING:  A background in chemical or life sciences
or biomedical engineering will be very helpful since we work mainly
in the pharmaceutical, chemical, biotech, healthcare, consumer packaged
goods, high technology and related industries.  A good understanding of
R&D, testing lab and office automation and information technology will
help you succeed because computing directors and R&D managers in
regulated industries are often main points of contact.

ASSOCIATION MISSION: Our mission is to catalyze emerging markets and
creation of leading-edge technologies that make it easier to discover
and develop new products that improve the quality of life.  We drive
the creation, convergence, effective usage, and continuous improvement
of automation technologies and methodologies that facilitate scientific
discovery, collaboration, and product development by technical and
business professionals.

ASSOCIATION PHILOSOPHY:  Everyone in our association succeeds best by
bringing a fun-loving spirit and a missionary zeal and commitment to
delivering leading edge research, engineering, technologies, and
business deals.  We have fun meeting complex technical and business
challenge
to our
members.   We employ bright, young-minded professionals who are highly
competent and accomplished in multi-company business and technology
development projects.  We reward our employees generously and give
them appropriate opportunities and challenges to stimulate their
professional growth.  Our success is measured by how well we delight
our members by defining and driving new markets that serve them.  We
love learning from others, and teaching and mentoring our members and
other customers.  We transfer the results of our research and
engineering work in ways that greatly improve their business operations
and make us all members of the association more profitable.

CONTACT:

Karen Coste, Office Manager
Collaborative Electronic Notebook Systems Association
800 West Cummings Park, Suite 5400
Woburn, MA 01801
(781) 935-9600 phone
(781) 935-3113 fax
e-mail: kcoste@censa.org
website: www.censa.org

Copyright  1998 - CENSA




From owner-repertoires@net.bio.net Mon Sep 21 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: Hakan Molin <Hakan.Molin@PAIN.SE.ASTRA.COM>
Newsgroups: bionet.molecules.repertoires
Subject: Positions available - MEDICINAL CHEMISTRY
Date: 22 Sep 1998 07:45:17 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 56
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> RESEARCH SCIENTISTS, MEDICINAL CHEMISTRY
> The Medicinal Chemistry Department at Astra Pain Control AB is in a phase
> of significant expansion. This will provide employment opportunities for
> chemists with skills in Organic chemistry/Medicinal chemistry ,
> Combinatorial chemistry, and Chemoinformatics.
> The research is project oriented and the main goal is to design and
> synthesize biologically active compounds for the discovery and development
> of new and improved drugs for the treatment of pain.
> For our laboratories at Novum Research Park, in Huddinge, outside
> Stockholm, Sweden we are seeking two candidates.
>
> RESEARCH SCIENTIST - COMBINATORIAL CHEMISTRY
> The successful candidate will take part in all aspects of the build-up and
> development of combinatorial chemistry within the department. Relevant
> background is a PhD degree in organic chemistry with experience in the
> field.
>
> RESEARCH SCIENTIST - ORGANIC CHEMISTRY/MEDICINAL CHEMISTRY
> The successful candidate will work in a drug discovery project team and
> primarily be engaged with the design and synthesis of substances for
> biological testing and in the development of synthetic methods. Relevant
> background is a PhD degree in organic chemistry or BS/MS degree with 2-5
> additional years of experience in the field.
> A pronounced interest in practical synthetic work and in project oriented
> teamwork is essential.
>
> We welcome your application to become a member of a research-intensive
> department in a growing international organisation.
>
> For further information, please contact:
> Jan-Erik Nystrom +46-(0)31-7762396 or +46-(0)8 55325439
> jan-erik.nystrom@pain.se.astra.com
> or
> Alf Claesson +46 - (0)8-553 27174, fax +46 (0)8-553 254 21
> alf.claesson@pain.se.astra.com
>
> Applications with full details should be sent no later than October 2
> 1998, to the following adress: Astra Pain Control AB, Claes-Gran Persson,
> Personnel Support & Information, S-15185 S=F6dert=E4lje, Sweden
>
> ASTRA is an international, research-based pharmaceutical company with
> subsidiaries in some fifty countries.. Every day millions of people all
> around the world use pharmaceuticals from Astra. Astra has approximately
> 20,000 employees, of whom a third are in Sweden. Sales in 1996 totaled
> approximately SEK 39 billion. For more information about Astra, see:
> www.astra.com.
>
> ASTRA PAIN CONTROL AB in S=F6dert=E4lje is a research company belonging to the
> Astra Group, with about 300 employees. Our products dominate the world
> market for local anaesthetics. Through research and development we create
> local anaesthetic and analgesic agents.
>
>




From owner-repertoires@net.bio.net Mon Sep 21 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: Linda Fei <lindafei@SYNCOMMBDL.COM>
Newsgroups: bionet.molecules.repertoires
Subject: Publication News
Date: 22 Sep 1998 02:15:18 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 37
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Dear Colleagues:

Here follows is the Publication News from Syncomm Corp.:

Dr. Jianping Qiu's article Protein Expression System has been presented in
the August Issue of Genetic Engineering News, overviewing the currant trend
in system for protein expression. Anyone who might be interested in
recombinant protein engineering and expression may request as electronic
copy of this article at linderfei@syncommbdl.com. You are also welcome to
discuss any protein expression issues with Dr.Jianping Qiu at
jpq@syncommbdl.com

Any reques or inquiry about the biotech services are also welcome:

1. Recombinant protein (including human recombinant antibodies) engineering
and expression
2. Recombinant protein production
3. Custom construction and biopanning of phage display system.
4. In vitro mutagenesis
   (see more at hppp://www.syncommbdl.com)

Thanks and regards.


Linda Fei
e-mail: lindafei@syncommbdl.com
Linda Fei
Marketing Manager
Syncomm Corporation
3401 Market Street
Philadelphia, PA 19104, U.S.A.
T. 215.387.2811
F. 215.387.2886
E-mail: lindafei@syncommbdl.com




From owner-repertoires@net.bio.net Wed Sep 23 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: "Dr. Wendy A. Warr" <wendy@WARR.COM>
Newsgroups: bionet.molecules.repertoires
Subject: Combinatorial chemistry - materials
Date: 24 Sep 1998 04:00:37 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 27
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The following is an upcoming meeting in the field of combinatorial
chemistry for materials science. It is the first major conference I have
come across that specializes in this interesting new field. I hope that
some of you will be interested.

Combinatorial Approaches for New Materials Discovery: Polymers,
Catalysis, Electronic Materials
January 21-22, 1999, The Fairmont Hotel, San Jose, CA, USA
Contact: Kim Takita, The Knowledge Foundation, 101 Merrimac Street,
Boston, MA, USA
Tel. 617 367 7979
Fax: 617 367 7912
E-mail kmtakita@knowledgefoundation.com
WWW http://www.knowledgefoundation.com

Apologies for duplicate postings.

Wendy
--
Dr Wendy A Warr
Wendy Warr & Associates, 6 Berwick Court
Holmes Chapel, Cheshire CW4 7HZ, England
Tel/fax +44 (0)1477 533837
wendy@warr.com   http://www.warr.com




From owner-repertoires@net.bio.net Wed Sep 30 23:00:00 1998
Path: biosci!biosci!not-for-mail
From: BIOSCI Administrator <biohelp@net.bio.net>
Newsgroups: bionet.molecules.repertoires
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 1 Oct 1998 04:40:52 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 236
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Message-ID: <199809280900.CAA01353@net.bio.net>
NNTP-Posting-Host: net.bio.net

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.





