From owner-repertoires@net.bio.net Sun Jan 10 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Shu-Kun Lin Newsgroups: bionet.molecules.repertoires Subject: 1998 MDPI Prize Announcement Date: 11 Jan 1999 01:46:05 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 36 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <76pvq7$r6v$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net 1998 MDPI Prize Announcement The first recipient of 1998 MDPI Prize is Dr. Jean-Pierre Vigneron from Paris, France. He is rewarded with this prize for his contribution in molecular diversity preservation by depositing a large number of chemical samples, many of them are natural products. The recipient will receive 3000 Swiss Francs and will be invited to visit Basel in 1999. The selection of recipient is carried out by discussions among the MDPI Foundation members. MDPI Prize will be announced every year to recognize the great efforts of chemists who significantly contributed to MDPI activities. Dr. Shu-Kun Lin President of MDPI Basel, 23 December 1998 --------------------------------------------------------- Dr. Shu-Kun Lin Molecular Diversity Preservation International (MDPI) Saengergasse 25, CH-4054 Basel, Switzerland http://www.mdpi.org/ E-mail lin@mdpi.org Tel. +41 79 322 3379, Fax +41 61 302 8918 -------------------------------------------------------- From owner-repertoires@net.bio.net Sun Jan 10 22:00:00 1999 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.molecules.repertoires Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 11 Jan 1999 01:29:06 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 238 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <199812281000.CAA07495@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-repertoires@net.bio.net Sun Jan 10 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Guenter Grethe Newsgroups: bionet.molecules.repertoires Subject: Fifth International Conference on Chemical Structures - Call for Date: 11 Jan 1999 02:12:10 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 22 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Dear colleagues, just a reminder that the deadline for submitting abstracts for oral or poster presentations at the Fifth International Conference on Chemical Structures is January 15, 1999. This is your chance to present your research at this important conference and to interact with your peers. For details about the conference and submitting abstracts please check our website at http://ChemWeb.com/conference/5iccs/5iccs.html Hope to hear from you soon. Sincerely yours, Guenter Grethe Conference Chair From owner-repertoires@net.bio.net Sun Jan 10 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "Z. G. Zhao" Newsgroups: bionet.molecules.repertoires Subject: Fwd: new conference Date: 11 Jan 1999 01:49:41 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 42 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <774jsb$gp7$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net >>Dear Colleagues, >> >>We would like to call to your attention the 16th American Peptide >>Symposium which will be held in Minneapolis from June 26-July 1, 1999. The >>"Call for Papers & Registration Information" was mailed to current members >>of the American Peptide Society just before Thanksgiving and should have >>been received by now. Requests for information should be sent via e-mail >>to 16aps@chem.umn.edu. In addition, please check our web site at >>www.chem.umn.edu/16aps, which contains all of the pertinent information >>and is now set up to accept both abstracts and registrations >>electronically. >> >>In setting as the theme for the meeting "Peptides for the New Millennium," >>we want to highlight how peptide science can play a role in fields as >>diverse as synthetic chemistry, pharmaceutical discovery, biomaterials, >>and proteomics, among the topics that will be featured. We hope that you >>will consider attending, and perhaps submit one or more abstracts. Feel >>free to pass along your suggestions to us, and also to spread the news >>about the Symposium to others in your professional circle. ============== Michael Bruck University of Arizona email: mbruck@u.arizona.edu Department of Chemistry voice: 520-626-6313 Old Chemistry Bldg, Room 329D fax: 520-621-8407 Tucson, AZ 85721 From owner-repertoires@net.bio.net Sun Jan 10 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Guenter Grethe Newsgroups: bionet.molecules.repertoires Subject: 5th Chemical Structures Conference - Abstract Submission Date: 11 Jan 1999 01:47:31 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 22 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <76skiv$epr$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net Happy New Year! !999 has arrived and the Fifth International Conference on Chemical Structures (June 6-10, 1999) in Noordwijkerhout, The Netherlands, is rapidly taking shape. This is just a short reminder that the deadline for submitting abstracts for oral presentations and/or posters is January 15, 1999. Details can be found at: http://ChemWeb.com/conference/5iccs/5iccs.html Best regards, Guenter Grethe Conference Chair From owner-repertoires@net.bio.net Wed Jan 13 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Frank Church Newsgroups: bionet.molecules.repertoires Subject: Postdoctoral Position Available! Date: 14 Jan 1999 06:40:36 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 78 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <77kda3$m7f$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net Dear Colleagues, Please circulate this ad to any graduate students in your laboratory that may be interested in the position described below. Thanks for your consideration of this request! Frank Church ********************************** Postdoctoral Research Associate Position Available Description of Position: Available immediately; Salary negotiable; Suggest background in biochemistry, molecular-cell biology or related field. Prior research experience in proteases and/or their inhibitors is very desirable, but not required. Research experience in one or more of the following areas is required: protein biochemistry-expression and characterization of recombinant proteins, molecular/cellular biology, enzymology; site-directed mutagenesis, immunohistochemistry/in situ hybridization, or tumor cell biology. Area of research project will be focused in structure-function relationships of serpins and serine proteases and in pathophysiology of thrombosis/hemostasis and tumor cell biology. The research area of this laboratory is concerned with serine proteases and their inhibitors (serpins) in human biology and in various disease processes (including thrombosis, tumor cell metastasis and wound healing). We study the following proteins: antithrombin III, heparin cofactor II, protein C inhibitor, plasminogen activator inhibitor-1, plasminogen activator inhibitor-2, maspin, thrombin, activated protein C, factor Xa, chymotrypsin, trypsin, and urokinase. Representative Recent Publications: (1) Myles, T., F.C. Church, H.C. Whinna, D. Monard, and S.R. Stone (1998) Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes. J. Biol. Chem. 273: 31203-31208; (2) Ciaccia, A.V., D.M. Monroe, and F.C. Church (1997) Arginine 200 of heparin cofactor II promotes intramolecular interactions of the acidic domain: Implications for thrombin inhibition. J. Biol. Chem. 272: 14074-14079; (3) Cooper, S.T., L.L. Neese, M.N. DiCuccio, D.K. Liles, M. Hoffman and F.C. Church (1996) Vascular localization of the heparin-binding serpins antithrombin, heparin cofactor II and protein C inhibitor. Clin. Appl. Thromb./Hemost. 2: 185-191; (4) Shirk, R.A, F. C. Church and W.D.. Wagner (1996) Arterial smooth muscle cell heparan sulfate proteoglycans accelerate thrombin inhibition by heparin cofactor II. Arterioscl. Thromb. Vasc. Biol. 16: 1138-1146; (5) Cooper, S.T., H.C. Whinna, T.P. Jackson, J.M. Boyd and F.C. Church (1995) Intermolecular interactions between protein C inhibitor and coagulation proteases. Biochemistry 34: 12991-12997; (6) Wu, H.-F., R.L. Lundblad, and F.C. Church (1995) Neutralization of heparin by neutrophil lactoferrin. Blood 85: 421-428. To pursue this opportunity (or to request further information): Please send CV, names and addresses of 2 or 3 references, and a cover letter indicating research experience to the address below (either by email or by normal mail). Frank C. Church, Ph.D. Division of Hematology-Oncology/Medicine Campus Box 7035; 932 Mary Ellen Jones Bldg. University of North Carolina at Chapel Hill School of Medicine Chapel Hill, NC 27599-7035 U.S.A. FAX- 919/966-7639 Email-fchurch@email.unc.edu Internet- http://serpins.med.unc.edu From owner-repertoires@net.bio.net Wed Jan 13 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Kim Takita Newsgroups: bionet.molecules.repertoires Subject: materials informatics Date: 14 Jan 1999 06:38:37 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 30 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <77kd9k$m6t$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net We are organizing a meeting focusing on informatics specifically for materials and chemicals (non-pharmaceutical). Our hope is that this meeting could help spur initiatives similar to Bioinformatics activities. We are finding quite a bit on bioinformatics, but having difficulty finding companies with a focus on materials. Topics we are interested in include both technological, as well as business issues associated with integration, management and sharing of information/databases. Are any of you aware of individuals or organizations we might speak to? Any help would be greatly appreciated. ------------------------------------------------------------------------ ---------- Kim Takita Vice President The Knowledge Foundation, Inc. 101 Merrimac Street Boston, MA 02114 Phone: 617-367-7979 ext. 202 Fax: 617-367-7912 E-Mail: kmtakita@knowledgefoundation.com http://www.knowledgefoundation.com From owner-repertoires@net.bio.net Tue Jan 19 22:00:00 1999 Path: biosci!biosci!not-for-mail From: MICHAEL KEENAN Newsgroups: bionet.molecules.repertoires Subject: Screening and Miniaturization Update Date: 20 Jan 1999 07:24:18 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 51 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <784i3r$esq$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net Back-to-Back Conferences Reveal the Latest Technical Advancements for Discovery IBC's 8th Annual International Conference on High-Throughput Screening March 1-3, 1999 The Claremont Resort, Berkeley, CA http://www.ibcusa.com/usc2270 * Featuring critical evaluations from big pharma! * Keynote: Timothy J. Rink, MA, MD, ScD, Aurora Biosciences * Network Reception in Large Exhibit Hall (sponsored by Molecular Devices) Plus! Two value-added symposia: * Engineering Cell Lines for Productive HTS (March 1, 1999) * Early High-Throughput ADME & Toxicology Screening (March 3, 1999) Conveniently scheduled back-to-back with IBC's 2nd Annual Conference on Miniaturization Technologies: Practical Applications for Drug Discovery and the Life Sciences March 4-5, 1999 The Claremont Resort, Berkeley, CA http://www.ibcusa.com/usc2269 * Moving to 1536 * Biochip Technologies & Microchannel Fluidics * Screening Applications and Challenges * Fluorescence Imaging Plus! "Instrumentation for 1536" Luncheon Demonstration Contact Dave Garcia at (508) 804-5428 for more information on participating in this demonstration. * Over SIXTY presentations, including Tutorials, Critiques, and Exhibit Demonstrations * Don't miss out -- reserve your place today! To reserve your place or request more information, please contact: Jeffrey Levinson IBC USA Conferences 225 Turnpike Road Southborough, MA 01772-1749 Tel: (508) 481-6400 ext. 632 Fax: (508) 481-4473 Email: jlevinson@ibcusa.com From owner-repertoires@net.bio.net Tue Jan 19 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Ed Madison Newsgroups: bionet.molecules.repertoires Subject: Postdoctoral Position Available! Date: 20 Jan 1999 07:29:51 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 26 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <784hvp$enp$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net One postdoctoral position is available at The Torrey Pines Institute for Molecular Studies to study serine protease structure/function relationships (particularly with respect to zymogen activation and substrate specificity), design of protease inhibitors, and/or the development of new technologies and techniques to study protease biochemistry and "chemical biology". Extensive experience in molecular biology, including PCR, site directed mutagenesis, phage display, and in vitro evolution of nucleic acids or proteins, is preferred. Experience with protease expression and purification, and kinetic analysis of enzyme activity and inhibition is also preferred. Representative publications from the laboratory include Nature 339, 721-723; Science 262, 419-421; PNAS 92, 7627-7631; JBC 270, 30486-30490; JBC 271, 28749-28752; JBC 272, 28-32; JBC 272, 16603-16609; NAR 25, 3371-3372; and Chemistry and Biology 5, 475-488. The Torrey Pines Institute for Molecular Studies provides a very stimulating scientific environment, and San Diego provides an exceptionally pleasant climate and much natural beauty. To apply, please send a curriculum vitae to - Edwin L. Madison, Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, CA 92121. From owner-repertoires@net.bio.net Wed Jan 20 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Dan Kenan Newsgroups: bionet.molecules.repertoires Subject: Postdoctoral Research Position Available Date: 21 Jan 1999 08:18:20 -0800 Organization: Duke University, Durham, NC, USA Lines: 15 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <7850ct$1ro$1@news.duke.edu> NNTP-Posting-Host: net.bio.net Postdoctoral research position available to study molecular alterations in breast and lung cancer using molecular profiling technologies. Position requires experience with molecular biology, protein biochemistry and cell culture. Experience with phage display and immunohistochemistry a strong plus. Send a letter of research experience, curriculum vitae, and the contact information for three references to: Daniel Kenan, M.D., Ph.D, Assistant Professor; Department of Pathology; Box 3020 Duke University Medical Center; Durham, NC 27710; Email: kenan001@mc.duke.edu. Duke University is an Equal Opportunity Employer. From owner-repertoires@net.bio.net Tue Jan 26 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Leemor Joshua-Tor Newsgroups: bionet.molecules.repertoires Subject: POSTDOCTORAL POSITION in STRUCTURAL BIOLOGY at COLD SPRING HARBOR Date: 27 Jan 1999 01:51:16 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 42 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <78mm51$jrt$1@mserv2.dl.ac.uk> NNTP-Posting-Host: net.bio.net POSTDOCTORAL POSITION in STRUCTURAL BIOLOGY at COLD SPRING HARBOR Applications are invited for a postdoctoral position in macromolecular crystallography at Cold Spring Harbor Laboratory to work on complexes involved in gene expression. The positions are available for highly motivated applicants with a Ph. D. and experience in either protein crystallography or a related field or those with experience in biochemistry or molecular biology and a keen interest in protein crystallography and structural biology. Experience in protein purification is an advantage. The position is available starting Spring 1999. Our X-ray crystallography facilities include a Rigaku generator, mirrors, an R-axis detector, an Oxford cryosystem and several graphics workstations. We share a beamline at the nearby National Synchrotron Light Source (NSLS) at Brookhaven. We also have state-of-the-art facilities for carrying out biochemical and molecular biology studies. Cold Spring Harbor provides a unique stimulating and very collaborative environment for rich scientific interactions. For details about CSHL please see our web site at: http://www.cshl.org/ Please send CV, list of publications, a summary of research experience and interests, and names and numbers of three references to Dr. Leemor Joshua-Tor, Cold Spring Harbor Laboratory, P. O. Box 100, Cold Spring Harbor, NY 11724. Tel. (516) 367 8821. For additional information or informal inquiries, please call or send e-mail to leemor@cshl.org ******************************************************************* Leemor Joshua-Tor, Ph.D. Assistant Investigator Keck Structural Biology Cold Spring Harbor Laboratory Tel. (516) 367 8821 1 Bungtown Road Fax (516) 367 8873 Cold Spring Harbor, NY 11724 e-mail: leemor@cshl.org ******************************************************************* From owner-repertoires@net.bio.net Sun Jan 31 22:00:00 1999 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.molecules.repertoires Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 1 Feb 1999 02:06:56 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 236 Sender: daemon@net.bio.net Approved: A.Wallace@Queens-Belfast.AC.UK Distribution: world Message-ID: <199901281000.CAA03561@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms.