From owner-repertoires@net.bio.net Wed Aug 04 12:22:00 1999
Path: biosci!biosci!not-for-mail
From: BIOSCI Administrator <biohelp@net.bio.net>
Newsgroups: bionet.molecules.repertoires
Subject: BIOSCI/bionet miniFAQ & Fundraiser
Date: 4 Aug 1999 06:22:10 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.





From owner-repertoires@net.bio.net Wed Aug 04 12:25:00 1999
Path: biosci!biosci!not-for-mail
From: Michael Sherrell <grizzlyan@mindspring.com>
Newsgroups: bionet.molecules.repertoires
Subject: 377 seqs, synths, LC/MSs, NMRs for sale
Date: 4 Aug 1999 06:24:53 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 51
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NNTP-Posting-Host: net.bio.net

Sequencers, synthesizers, mass spectrometers, NMRs for sale:

Peptide and oligo synthesizers and sequencers:
     ABI 392: $2,500 (electronics working; add $3,000 for rebuild/warranty)
     ABI 394: $12,500 (Valve blocks rebuilt; warranteed)
     ABI 390Z: $4,000 (50-100uM yields)
     ABI 430: $6,000 (electronics working; add $5,000 for rebuild/warranty)
     ABI 431: $12,500 (Rebuilt, warranteed)
     ABI 433: $19,000 (ABI upgrade)
     PerSeptive 9050+: $6,000 (As is/was working when decommissioned; add $3,500 for rebuild/warranty)
     ABI 373 stretch: $9,000 (Big dye upgrade; under ABI service contract)
     ABI 373 stretch: $7,000 (4-filter)
     ABI 377: $80,000 (96 lanes; under ABI service contract; quantity discounts for 2 or more)
     ABI 377: $60,000 (48-lane; under ABI contract)
     ABI Procise 492: $45,000 obo (ABI-certified)
LC/Mass spectrometers:
     Sciex API III+ LC/MS/MS: $ 59,000 (ES, APCI, under PE service contract)
     Sciex API 300: $100,000 (365 upgrade, PE install/warranty available)
     HP 1100 benchtop LC/MSD: $120,000 (APCI & API-electrospray, autosampler, DAD detector, < 1 year old)
     Finnigan LCQ: $120,000 ("Classic" MS^n; 1.5 yrs old; site license included)
     PE Mariner: $140,000 (1998 model; includes refurb, install and 1 yr. warranty)
     Finnigan Navigator benchtop LC/MS: $ 75,000; 18 mos. old; factory refurb, install & 90-day warr. included
     Finnigan TSQ 7000 LC+GC/MS/MS: $ 97,500; current software; API-1 source; under Finnigan service contract
     Sciex 150 benchtop LC/MS: $ 98,000; 2 yrs old; includes Gilson 215 liquid handler, ELSD detector & HP 1100 HPLC.
      Finnigan SSQ 7000 LC/MS: $130,000; API-2 source, electrospray + APCI, Excaliber software, factory refurb, 90-day warranty, install included
     Micromass II: $50,000; ES, APCI, 3 yrs. old, includes HPLC, NOT Z-spray
     Fisons VG Platform: make offer; to 3000 daltons; under service contract
     HP 5989B LC+GC/MS: $ 35,000; Extended mass range (2000 amu), hex ion guide; HPLC & warranty avail.
     Finnigan MAT 90: $30,000; Hi-resolution magnetic sector
     Fisons VG 2000: <$100,000
MALDI-TOFs:
     Voyager RP: $60,000; NOT DE; 4 yrs. old; running in lab now
     LaserMAT 3000: $24,000; new detector and laser; +$2,000/install; service agreements available
     Hewlett-Packard G2025A $ 50,000
NMRs:
     Bruker AMX 600: call for specs and price
     Varian Unity 500+: $245,000; broadband; includes install/warranty
     Varian Unity 500: $180,000; incl. install/warranty
     Bruker AM360: $85,000; broadband; widebore; install included
     Varian Unity 500: call for price; broadband
Also available:
      Hitachi 570 scanning electron microscope, Kevex detector, running now, $35,000.
      BD FACSVantage and assorted FACScans
Various other seqencers, synthesizers etc. are available; please inquire or check the website.

Michael Sherrell
Grizzly Analytical
707 887 2919/fax 707 887 9834
www.grizzlyanalytical.com



From owner-repertoires@net.bio.net Mon Aug 09 11:26:00 1999
Path: biosci!biosci!not-for-mail
From: Shu-Kun Lin <lin@mdpi.org>
Newsgroups: bionet.molecules.repertoires
Subject: ECSOC-3: Electronic Conference in Organic Synthesis deadline for
Date: 9 Aug 1999 05:26:30 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 28
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Dear Colleagues,

The deadline for submission of papers to the 3rd International
Electronic Conference in Organic Synthesis (ECSOC-3 at
http://www.mdpi.org/ecsoc-3.htm) is postponed to August 20, 1999.

This conference will take place during September 1-30, 1999 on the
Internet, providing the opportunity for immediate feedback
and informal discussions. The organizers would like to
encourage you to use this medium to have your
research results made available to the global
chemistry community. Please visit the ECSOC-3 website
http://www.mdpi.org/ecsoc-3.htm for more information.

Shu-Kun Lin
ECSOC-3 Secretary

--
Dr. Shu-Kun Lin
Molecular Diversity Preservation International (MDPI)
Saengergasse 25, CH-4054 Basel, Switzerland
Tel. +41 79 322 3379, Fax +41 61 302 8918
E-mail: lin@mdpi.org
http://www.mdpi.org/lin/





From owner-repertoires@net.bio.net Mon Aug 09 13:26:00 1999
Path: biosci!biosci!not-for-mail
From: Shu-Kun Lin <lin@mdpi.org>
Newsgroups: bionet.molecules.repertoires
Subject: Great progress in Molecules' MolBank http://www.molbank.org
Date: 9 Aug 1999 07:26:36 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 44
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NNTP-Posting-Host: net.bio.net

(Excuse me for sending to several mailing lists)

Our MolBank section (http://www.molbank.org) of Molecules
is perhaps the first, almost perfect electronic journal in chemistry.
You can already search on the website www.molbank.org all the
published compounds by 2D substructure search.

MolBank new features:
- easy, electronic procedure to submit a paper
- free access from the Internet with powerful searching tools
- IUPAC Names (for the titles) generated by CAD (http://www.acdlabs.com)

in addition to the following
- one-paper for one reaction with one fully characterized product
- very fast publication, particularly suitable for
publishing short communications to have the priority the a chemist
is the first to have synthesized a compound or have fully
characterized a natural product
- easy publication of short notes of scattered unassembled experimental
data for individual compounds which is conventionally not
publishable

I would like to introduce Dr. Luc Patiny as the MolBank
section Editor of MOLECULES
(http://www.mdpi.org/molecules/editors.htm#molbank). Dr. Patiny is from
the Institute of Organic Chemistry, University Lausanne, Switzerland.

We will publish a large issue soon in August 1999.

Enjoy it!

Shu-Kun

--
Dr. Shu-Kun Lin
Molecular Diversity Preservation International (MDPI)
Saengergasse 25, CH-4054 Basel, Switzerland
Tel. +41 79 322 3379, Fax +41 61 302 8918
E-mail: lin@mdpi.org
http://www.mdpi.org/lin/





From owner-repertoires@net.bio.net Fri Aug 13 16:39:00 1999
Path: biosci!biosci!not-for-mail
From: "Dr. Wendy A. Warr" <wendy@warr.com>
Newsgroups: bionet.molecules.repertoires
Subject: "Chemoinformaticians"
Date: 13 Aug 1999 10:39:19 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 38
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Colleagues,

Please excuse multiple postings. In connection with a paper I am giving
in an ACS COMP Division symposium in New Orleans, I want to re-open the
discussion on chemoinformatics that we had on one of these lists some
years ago. Not only has the term "chemoinformatics" become even more
strongly entrenched (though some say "cheminformatics) but some
companies now formally use the awful job title "chemoinformatician".

Leaving aside linguistic considerations, I would be interested in
subscribers' views on the following.

What does a chemoinformatician actually do that a computational chemist
or chemical information professional does not do?

What skills would you look for if you were recruiting one of these
scientists, under whatever job title?

Is there a shortage of such skills and, if so, what should the higher
education establishment be doing (if anything) to help supply meet
demand?

Please reply to me in person but I will summarize the comments for the
list(s) if this seems desirable.

Wendy
--
Dr Wendy A Warr
Wendy Warr & Associates, 6 Berwick Court
Holmes Chapel, Cheshire CW4 7HZ, England
Tel/fax +44 (0)1477 533837
wendy@warr.com   http://www.warr.com







From owner-repertoires@net.bio.net Fri Aug 13 16:50:00 1999
Path: biosci!biosci!not-for-mail
From: Peter Butler <peter.butler@WKAP.NL>
Newsgroups: bionet.molecules.repertoires
Subject: Annual Reports in Combinatorial Chemistry and Molecular Diversity
Date: 13 Aug 1999 10:50:46 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 17
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We are pleased to announce the publication of Annual Reports in
Combinatorial Chemistry & Molecular Diversity Volume 2
edited by Michael R. Pavia & Walter H. Moos

Further information about this publication can be found at:
http://www.wkap.nl/book.htm/0-7923-5722-1

Please feel free to contact me with any questions.

Peter Butler
Kluwer Academic Publishers
peter.butler@wkap.nl






From owner-repertoires@net.bio.net Fri Aug 13 16:57:00 1999
Path: biosci!biosci!not-for-mail
From: Steve Heller <chem@FELDMANN.NIST.GOV>
Newsgroups: bionet.molecules.repertoires
Subject: ChemInt'99 - Upcoming Deadlines/Workshops
Date: 13 Aug 1999 10:57:06 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 76
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Message-ID: <Pine.SOL.3.96.990813111060.20754B-100000@feldmann.nist.gov>
NNTP-Posting-Host: net.bio.net

This note is a reminder that the deadline for poster abstracts for
Chemistry & the Internet - ChemInt'99 is September 1, 1999.  September is
the deadline for the special hotel rates for the conference.

In addition to the previously announced program, two vendor workshops
- from ACD Labs and Synopsys - have been added to the meeting.

The Chemistry and the Internet (ChemInt'99) meeting being held in at
Georgetown University in Washington DC on September 25-27, 1999.

The program of invited speakers and panel members of the 3 panel sessions
is available on the meeting web site - www.chemint.org

You are urged to look at the program and to consider submitting a
poster paper to the meeting.

The main lecturers for the meeting will be:

Alan Arnold, University College (UNSW)
Steven Bachrach, Northern Illinois University
Robert Bovenschulte, ACS
Stephen Boyer, IBM
Donald DeCoste, University of Illinois at Urbana-Champaign
Karl Harrison, Oxford University
Clemens Jochum, Deutsche Bank
Gary Mallard, NIST
Tom Pierce, Rohm & Haas
Jerome Reichman, Vanderbilt
Achim Zielesny, Bayer AG


The (current) corporate sponsors for the meeting are:
ChemWeb and the Internet Journal of Chemistry


Technical Sponsors are:

ACS CINF Division
ACS COMP Division
The Chemical Structure Association (CSA)
Georgetown University - Department of Chemistry
International Union of Pure and Applied Chemistry (IUPAC) (pending)
Japan Association for International Chemical Information (JAICI)
Special Libraries Association (SLA) Chemistry Division
Royal Society of Chemistry (RSC)/ChemSoc



Steve Heller


Steve Heller, Guest Researcher
NIST/SRD, Mail Stop: 820/113
820 Diamond Avenue, Room 101
Gaithersburg, MD 20899-2310 USA
E-mail:  chem@feldmann.nist.gov











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From owner-repertoires@net.bio.net Tue Aug 31 11:00:00 1999
Path: biosci!biosci!not-for-mail
From: Michael Sherrell <grizzlyan@mindspring.com>
Newsgroups: bionet.molecules.repertoires
Subject: ABI 377 for sale
Date: 31 Aug 1999 05:00:54 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 9
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Approved: A.Wallace@Queens-Belfast.AC.UK
Distribution: world
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NNTP-Posting-Host: net.bio.net

ABI 377, 1998 model, 96-lane, still under service contract, Sequence Analysis and Genescan, computer, monitor, buffer chambers, spacers, combs and cassettes, US$72,000. Service records available. Must act by Wednesday Sept. 1.

Michael Sherrell
Grizzly Analytical (USA)
707 887 2919/fax 707 887 9834
www.grizzlyanalytical.com




